LOCUS       gnlProkkaGAGFMGDE_97   15841 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GAGFMGDE_97.
ACCESSION   gnlProkkaGAGFMGDE_97
VERSION     gnlProkkaGAGFMGDE_97
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 22:06:51
            Original ID  :: gnl|Prokka|GAGFMGDE_97
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15841
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15841
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5107:5841]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5108..5841
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..15841
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15841
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             814..1467
                     /locus_tag="ctg97_1"
                     /transl_table=11
                     /translation="MDYQSIVTFVMEMAGSVAFAASGAMVGVERNMDIFGVSVLGVATA
                     VGGGMIRDIVLGIIPPAVFTNPVYALVSVLASCIVFFIFYFKRELLQGHRRETYDKIML
                     AMDSVGLGIFTVVGVNTGIRQGYMDNVFLLVFLGTITGVGGGLLRDMMASVPPYIFVKH
                     IYACASIIGAVVCVYMNRFVGNVQAMVVSSIVVVLIRYLAAHYRWNLPRLSPHE"
     CDS             complement(1376..1912)
                     /locus_tag="ctg97_2"
                     /transl_table=11
                     /translation="MNLKGAVVMRKKLNITEGIFPMPVLMVATYNEDGSINVMNAAWGT
                     MQERDTVALNLTETHKTVQNIKARGAFTVSIADAAHVTEADYFGVESGNREPDKFARSR
                     LTATKSETVDAPIINNFPPRTKRQSDKLSLTALNITCLILYGILPIHVVTAWADSSGNV
                     LPDIGSAPLQLMILP"
     CDS             complement(2379..3677)
                     /locus_tag="ctg97_3"
                     /transl_table=11
                     /translation="MEYIILLIFSFFTEAVILWQYAASLFSPSHSGKKRLTLLSVLYVL
                     LFFLSLLGQTWLNIISFFVINTVFLYIMFNLKLLLALFHSAILTAIMGISELAVLGMIS
                     RFFPHFLLEASVGLVFYTVFSKITFFAVVYLLSWLFKGNKAAQEPYGHSEILLMFIPLS
                     SILMMFTLLSIGETTAYAPPVDFLVTICAVFLLLVNLLVFGINQYNTKRSQEYADLQLL
                     LQKESDSVEYYEMMLAQNENQSILIHDIKKHLQSIRLLNEKNDSDKINDYIQQLMESSD
                     LKETTKLCDHEMLNSILCRYQRHCNDKHIIFHTDIRSGTVQHIYPRDLTSLFCNLLENA
                     VESAENIPDSFIELTVQKKENSPFLIIILINSCQNTPVYNPEGLPISHKSDNGRHGFGI
                     KSIKKVVKQYHGNLQMYYDNDSGTFHTILTLKQ"
     CDS             complement(3684..4391)
                     /locus_tag="ctg97_4"
                     /transl_table=11
                     /translation="MRILICDDDTLIIEQLKKYIESYFESNHLKCPELVSFTSGEALLT
                     DKGEKDIVFLDIEMPGMNGIYVGNELKKANRNVIVFVVTSYSEYLDEAMRFHVFRYLSK
                     PLDKQRFFRNLKDALAYYNSITLKIPVETKQAVYSFPASQIIAIEAQGRKVIVHTARQD
                     FDSIHNMNYWLEKLPQNSFFQTHRSFIVNFEHIVDFDHSTVHLSNPQITAYLTRRKYSS
                     FRNAYLLYLESMR"
     CDS             complement(4483..4812)
                     /locus_tag="ctg97_5"
                     /transl_table=11
                     /translation="MGNRIKIRRKELRIKQAELAERLNISNNHMSSIENGRQKSSLDIF
                     IQICNLLNVTPDYLLLGSMHAYNIPQDIIDKLRLCNQSDIELAGDFIELLVKRNNKATH
                     NEPKL"
     CDS             5108..5257
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg97_6"
                     /sec_met_domain="TIGR04223 (E-value: 1.1e-14, bitscore:
                     44.5, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKEVTKSVAKGMKAALDVVLRTEANTASCLIMYQPKAPKELMNY
                     RRNK"
     CDS             5257..5841
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg97_7"
                     /sec_met_domain="AgrB (E-value: 1.3e-36, bitscore: 115.9,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKCTDTVVNWMIRCNAINEADKELYKYALYSFFLLVSPLILAGV
                     IGFGLGSVKHGVALIFPFVVLRKFSGGYHAKNLHTCILGSGFLLFLCIMLSMHVQCDLK
                     LAIATVIASVSLITFSPIDSENRRLDTNEKRTYKKTTVFFVILFGLLDIALFLLGKYIY
                     TICFSVGILLTAGLQVPCIVKKMCKSTKNRL"
     CDS             5842..5952
                     /locus_tag="ctg97_8"
                     /transl_table=11
                     /translation="MSFGAKGVEIMAKIKIIKFVIDLIKVLYLQLIQFVH"
     CDS             6056..6439
                     /locus_tag="ctg97_9"
                     /transl_table=11
                     /translation="MTHKKEVVFSLLFVIMVLCTGCSDKDNGDTSKNNRTSGESFVQEE
                     TIESTDNTDNADGSSAPTPELKTPRTKKELEDALGTVNESGKWTPPAGSHIDPKTGNIL
                     NKDGVVVGTTQEPYSKARPGSQG"
     CDS             7005..7211
                     /locus_tag="ctg97_10"
                     /transl_table=11
                     /translation="MIKIETKVLFQERVMVMALAQATKSHEPTYTINDAMDVLLSRLDE
                     AIDDMESDRVQIVEEAWAEIDAI"
     CDS             complement(7550..9073)
                     /locus_tag="ctg97_11"
                     /transl_table=11
                     /translation="MFGAGNGFIGKIGGIATEAHYGSGMLPDGVPFWAFLIFQTVFCAT
                     SATIVSGAMAERTKFLSYCVYSLMISLVVYPVSGHWIWGGGFISQMGFHDFAGSCAVHM
                     VGGVAALIGAIILGPRIGKYTKDGKSKAIPGHNLTVGALGVFILWFCWFGFNGASTVSM
                     EGDAIVSAGKIFVTTNLAAAVATVTVMIITWVRYKKPDVSMSLNGSLAGLVAITAGCDT
                     VSPTSAAIIGIASGFIVVFGIEFIDKVLKIDDPVGAVGVHGLNGAFGTLAVGLFSDGSG
                     TDWKGLLTGGGFHGFGVQFTGMIITIAWVVVTMTIIFQVIKHTIGLRVSAEEEIAGLDS
                     KEHGLASAYDGFAMAGVPTPMGTSIKAPVVTARPSAPAESVPELPKEGVHKLTKVVIIT
                     RQNKLDEFMQAMNEIGVTGITITNVLGCGVQKGAPSYYRGVEMEMNLLPKVKIEIVVSL
                     VPVQKVIETAKAVLHTGQIGDGKVFVYDIENVVKIRTGEEGYLALQDTK"
     CDS             complement(9561..11660)
                     /locus_tag="ctg97_12"
                     /transl_table=11
                     /translation="MAQNIPELYGSLVFNDKVMRSKLPKDMYKALKKTIESGTHLELDV
                     ANSVAVAMKEWATENGATHYTHWFQPMTNVTAEKHDSFISPTGDGQVIMDFSGKELVKG
                     EPDASSFPSGGLRATFEARGYTAWDPTSPAFIKDGTLYIPTAFCSYSGEALDKKTPLLR
                     SMQTLDKEATKLLHIIGNKDVKHVNTTVGPEQEYFLVDKELYKQRKDLVFCGRTLIGAP
                     APKGQEMEDHYFGALKPRVAAYMHDLDVELWKLGIPAKTKHNEVAPAQHELAPVFDTTN
                     VAVDHNQLTMEVMKKVADKHGLVCLLHEKPFEGINGSGKHNNWSMITDTGVNILDPGKT
                     PAENTQFLIFLTAVIKAVDEYADVLRISVASAGNDHRLGANEAPPAVVSVFLGDELTEV
                     LKSIENDEYFAGSRAVQMDIGAKVLPHFVKDNTDRNRTSPFAFTGNKFEFRMLGSEASV
                     ANPNIILNTAVAECVHQFAEQLKDVPEDKMEDAIHELIKKTIIDHKRVIFNGNGYTDEW
                     IEEAEKRGLFNLKSTPDALPQWIADKNIELFTKYHIFTKEEIESRYEIWLESYSKILNI
                     ESNTMVEMVQKDFLPSVFAYIDKVAATAVAKKSVVSDVSTASEGKLIKELSQLADEIST
                     GLETLKADTAKALATEDPLANAKAYQTVVLSDMDELRKSVDAAETLIPDALLPYPTYDK
                     LLFSV"
     CDS             12014..13498
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg97_13"
                     /sec_met_domain="GATase_7 (E-value: 1.5e-23, bitscore:
                     73.3, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAGFESKVKVRQENTIGGNQMAGIKEECGVFGIYDLDGGNVVPS
                     IYYGLTSLQHRGQESCGLAVSDTKGERGNVKFHKDLGLVSEVLRQDVVRKYEGDIGIGH
                     VRYSTTGASVAENAQPLVLSYVKGTLALAHNGNLVNTPELKWELIQNGAIFHTTTDSEV
                     IAFHIARERVHSKTVEEAVLKTAKKIKGAYGLVVMSPRKLIAVRDPYGLKPLCLGKRGN
                     AYVIASESCALTSVSAEFIRDIEPGEILTITKDGLKSNKELASAAAKRAHCVFEYIYFA
                     RLDSTIDGVKVYDARIRGGKSLAKSYPVEADIVTGVPESGLPAAKGYSEASGIPFAFAF
                     YKNSYIGRTFIKPTQEERESSVHLKLSVLESVVKDKRIVLVDDSIVRGTTIANLIHMLK
                     EAGAKEVHVRISSPPFLHPCYFGTDVPSNDQLIAASHSTEEICKMIGADSLGYMQTDYL
                     EGMAGGLPLCKACFDGNYPMEIPDYTNAEFADIVKC"
     CDS             13744..13995
                     /locus_tag="ctg97_14"
                     /transl_table=11
                     /translation="MFSERVITMSQSKIKLNATEEVQEFVNAASRCDFDIDVYYNRFLI
                     DAKSILGVLSLDLTRELTVDCHGESREFDRTLKKFAVA"
ORIGIN
        1 tctgttttac ggacgcgaag tccaaggaag aaaaagatat ccaattgcta cctacattct
       61 aacagcttaa gcaacaagat ggataattcc ttactggatg taagggatat taaccataaa
      121 tatattgtag taggaagaaa gttataccag ccagtgcagt ccgctgtcac cgaaagtggg
      181 gaaaagatat gcagagccgt ccaaacggaa agagagaggg ttgtacagag atggaaacag
      241 aacctataac gcagatgccg taggcgcata taatatcctg agaaaatatc actccgtatc
      301 cggagtaaaa aagaactgtc cgtaaccgga ctgaaaacac cggaaataat aaaagtagct
      361 gtatagctct aaagagcaaa cagtagtggt gtcatggatg caccctgaaa aaaaggcggt
      421 atcccgcctt aattcagatg ctctggtaac tcagttgccg agtaattcac ttactatact
      481 atgctgaagg tgttcgcgaa gtatataagt ttatctatat gaaatggaat aaatagtcga
      541 ttttctgata ctgattgaga gtaaagactc tttcacgtga cgttcaaaaa atcgactttt
      601 tatcttggat aattcagtgg aatctcctgc ttcaattatg aaaacattaa gtgatgaacg
      661 gagatttact gatattttta tagcaattcc agaaaataat gcaattaaga cagttcagca
      721 ttttcctgtc tttcgtgctt tgcaggagtg cattagttgc attgttttct gggattataa
      781 aagaaagata ggatggggag ttaaaaaaca aatatggatt atcagtcaat tgtaacattt
      841 gttatggaaa tggccggttc agtggcgttt gctgcttccg gagcgatggt gggcgttgaa
      901 cggaatatgg atattttcgg cgtgagcgtt ctgggagttg caacagcagt aggcggagga
      961 atgatcaggg atattgttct ggggatcatc cctccggctg tatttaccaa tcctgtatat
     1021 gcactggtgt cagtgcttgc ttcctgcatt gttttcttta ttttttattt caagagagaa
     1081 ttgcttcagg ggcacaggcg tgagacctac gataaaatca tgctggcaat ggactctgtc
     1141 gggcttggga tttttacagt agtaggagta aatacaggaa tccgccaggg atatatggac
     1201 aatgtgttcc tgcttgtatt tcttggaacc attacgggag taggcggcgg tctgcttaga
     1261 gatatgatgg cgagtgtacc gccgtatatt tttgtaaaac atatctatgc ctgtgcctcc
     1321 atcattggtg cagttgtatg cgtatatatg aatcgatttg tgggaaatgt acaggctatg
     1381 gtagtatcat caattgtagt ggtgctgatc cgatatctgg cagcacatta ccgctggaat
     1441 ctgcccaggc tgtcaccaca tgaataggaa ggataccgta taaaatcaga caggtaatat
     1501 ttagcgcagt caggctgagt ttgtctgact gtctttttgt tcgaggagga aaattattga
     1561 taatcggagc atctacagtt tcagattttg tggcggtcag acggctgcgg gcaaatttat
     1621 caggctcgcg attaccggat tctacaccga aatagtcagc ttctgttaca tgtgcggcat
     1681 ccgcgatgct gacggtaaat gcaccgcgtg ctttgatatt ctgtacggtt ttatgggtct
     1741 cggtaaggtt caatgcaact gtgtcacgtt cctgcatcgt accccaggca gcgttcatta
     1801 cattgatgct tccgtcttca ttataggttg caaccatcaa tacaggcata ggaaaaatgc
     1861 cttctgtaat atttaatttt tttctcatta caacagcccc tttcagattc aattgacagg
     1921 ataatatatc ctgctataaa tgagcaagtt tgaaaaaatg cacaaaatta tcctgctaat
     1981 ttcataaatg cttcaaaatc atcacttgct tttgcacata ggaatagata ctgatacttt
     2041 tcctgatgaa cggcactaca gattcgatga tatccatctt gaaaagatcg atatttgcca
     2101 gttcctgtga cacaaataca atgtgccagt gacatcagca gccagtatct ctgtatttcc
     2161 tttgagaaac ggatctggta tgtatccagt gccagacggt ttttacattg cctgaaaaat
     2221 atctcgatcg gccatcgaca cacataacag gaaaagatct ctttctttta tgcaaaatca
     2281 cgaacttgct catttatagt gatataaaac aacatcaatg catgctgaaa tatgtaaaaa
     2341 ggcaatcgta taaaattgcg attgccagat tttaatattt actgctttaa ggttaggatt
     2401 gtatggaagg taccggaatc attatcataa tacatttgca aatttccatg gtactgtttt
     2461 acgacttttt taatgctttt gattccgaat ccatgtctgc cattgtctga tttatgggat
     2521 ataggaagtc cctctggatt atatacaggg gtattttggc aggagttgat gagtatgata
     2581 ataagaaagg gtgaattttc tttcttttgt acggtgagct caataaaaga gtctggaata
     2641 ttctctgctg attccactgc attctccaat aagttacaga ataaagaagt caaatcgcgc
     2701 ggatatatat gttgtaccgt gccgcttctg atgtcagtgt gaaaaataat gtgcttatca
     2761 ttgcagtggc gctgatagcg gcacagaatg gagtttagca tttcatgatc acagagtttt
     2821 gtggtttcct ttaagtcgga agattccatg agttgttgta tatagtcatt tattttatcg
     2881 gaatcatttt tttcgttcag taatctgatt gattgaagat gtttctttat atcgtggatc
     2941 aaaatgctct ggttctcgtt ttgtgcaagc atcatttcat agtattcaac agaatcggat
     3001 tctttctgga gcagtaactg caaatcggca tattcctgtg atctttttgt gttatattgg
     3061 ttgattccaa atacaagtag gttgaccagc aacagaaaaa cggcacagat tgttactaga
     3121 aaatcaaccg gtggggcata tgcggttgtt tcaccaatag aaagaagagt aaacatcata
     3181 agaatagagg aaagcgggat gaacatcaag agaatttcgg agtgaccgta cggttcttga
     3241 gctgctttgt tccccttgaa gagccaactt aacaagtaaa cgactgcaaa aaaggtaatt
     3301 ttgctaaata cggtataaaa aacaagtccg acacttgctt ctaagagaaa atggggaaag
     3361 aatcttgata tcatccccaa aactgcaagt tcagatattc ccataatcgc tgtaagtata
     3421 gcggaatgga agagtgccaa taataacttg aggttaaaca ttatatagag gaaaacagtg
     3481 tttatcacaa aaaaactgat aatattcagc catgtttgcc caagcaggga aagaaaaaac
     3541 aacagtacat aaagaacact taatagagtc agtctctttt taccgctatg agaaggggaa
     3601 aaaaggctgg cggcgtactg ccataagata accgcttctg taaaaaaact aaaaataagt
     3661 aaaataatat attccattta ttttcacctc atgctttcca gatatagtag atatgcattt
     3721 ctgaaggaac tgtatttcct gcgtgtcagg taagcggtaa tctgaggatt tgataaatgt
     3781 acggtggagt gatcaaagtc cacaatatgt tcgaagttaa caataaagct ccggtgtgtc
     3841 tgaaaaaaac tgttttgggg aagcttttcc aaccagtaat tcatattatg aatagagtca
     3901 aagtcctgac gggcagtatg tacaattact tttcgcccct gagcttctat ggcaataatc
     3961 tgcgaagcag gaaacgaata taccgcctgt tttgtttcca caggaatttt gagtgtaatg
     4021 gaattgtaat aagctaaggc atccttcaga tttcggaaaa aacgctgctt atctagaggt
     4081 ttggaaaggt aacggaatac atgaaaacgc attgcttcat ccaaatattc agaataagag
     4141 gtgacaacaa aaacgatcac atttctattt gcttttttta attcattccc aacatagatt
     4201 ccattcatgc caggcatttc gatatccaga aaaacaatat ccttttcacc tttgtcagtt
     4261 aacaaagctt caccactggt aaaagaaact aattcaggac attttaaatg gttggactca
     4321 aagtaggatt cgatatactt cttcaattgt tcaatgatca gagtgtcatc atcacaaatt
     4381 aaaatacgca ttttttcacc tgactttcta aatagatgta tgtgtacatc ttatcacata
     4441 gaatttccaa atgcaaaaaa tgcgtatgaa aagacaattt aattacaatt ttggttcatt
     4501 atgtgttgct ttgttatttc gttttacaag cagttcgata aagtctccgg caagctctat
     4561 gtcggattga ttacataacc gtagtttatc aataatatcc tgtggaatat tataagcgtg
     4621 catactgccg agcagaaggt agtcaggtgt aacattgagt aaattacaaa tctgaatgaa
     4681 aatatccaga cttgattttt gccttccgtt ttcgattgat gacatatggt tattggatat
     4741 atttaatctt tcggcaagtt ctgcctgttt tatccgtaat tcttttctgc gtattttgat
     4801 gcggtttccc ataccttcat attgaaattc tatttatccc accttctttc agtagaattt
     4861 taccaataga actaaataaa aagaagaatg taacaaagaa ctattctgca atatattaaa
     4921 caaactgata tttatatata aataattctg tatcacatat tatttttcgt agaaaagagg
     4981 gaaattatcc aatattgtaa agaatcattc cgttcattcc aaaggggtcg tttatttgat
     5041 taaagtggta tatgattgct tatgtgaaaa tcaatgacaa attttagtgg aaaggagaga
     5101 ggtcattatg aagaaagagg taactaaatc ggttgcaaaa ggaatgaaag cagcattaga
     5161 tgttgtgtta cggacagaag ctaacacagc ttcttgtctt atcatgtatc agcctaaggc
     5221 accgaaagaa ttaatgaact acaggagaaa caagtaatgg aaaaatgtac agatacagta
     5281 gtaaattgga tgatccggtg taatgcgata aacgaggcgg ataaggaact ttacaagtat
     5341 gcattatata gtttttttct attggtatca ccacttatcc ttgcaggagt tattggcttt
     5401 ggcttgggaa gcgtaaaaca cggagttgct cttatttttc cgtttgtggt tctgagaaaa
     5461 tttagtggtg gttatcatgc aaaaaatttg cacacttgta ttcttggatc tggttttcta
     5521 ttgtttctgt gcataatgtt atcaatgcat gtgcaatgtg atttgaagtt ggcaatagct
     5581 acagttattg cgtctgtgag cctgattaca tttagtccaa tagacagtga aaacagaaga
     5641 cttgatacta acgagaaaag gacatataaa aaaacaacag tgttcttcgt gatactgttt
     5701 gggctgttag atatagcttt atttttgctg ggaaagtaca tctatacaat ctgtttttct
     5761 gttgggatat tactgacagc aggcttacaa gtaccttgta tcgtaaagaa aatgtgtaaa
     5821 tcgaccaaaa acagactgta aatgtcgttt ggtgcaaaag gggttgaaat catggcaaaa
     5881 ataaagataa taaagtttgt cattgatttg atcaaagttc tttatttaca gttaattcag
     5941 tttgttcatt gaaagggagt ggattccaat gggacaatga tagaattcta tcactttaaa
     6001 ttgagtagtt cggttcggag tagttaaacg ggcataatgg aggtaaaaga ttaaaatgac
     6061 acataagaaa gaagttgttt ttagcttgtt gtttgtaata atggtgttat gtacaggctg
     6121 cagtgataaa gataatggag atacgtctaa aaataacagg acttcaggag aatcatttgt
     6181 tcaagaagaa actattgaga gtactgacaa tacagacaat gcagacggca gctcggcacc
     6241 aacgccagaa ctgaaaacgc cccgaacgaa aaaggaattg gaagatgcgc ttggtacagt
     6301 gaatgagtcg ggaaaatgga cgccaccagc cggttctcat atagatccca aaacaggtaa
     6361 tatactgaat aaagatgggg tcgtggttgg aactacgcag gaaccttata gtaaagcacg
     6421 tccaggttct caaggatgat gatatggtgt aaaaaaatta tgggaggaaa agattatgaa
     6481 gtatatgaga aaaaactcat ttgtagtgtg tttggtcata agtgcaattc ttttgacaag
     6541 ttcatttgca atgccggtgc ttgctgcgga aaatacagga attgaaacaa gctctgtcac
     6601 gagaagcgta ccgggatatt acaagtgcac agggtcggat gtaaatatca gatcaggccc
     6661 tggaacacaa tatacaatag taggcacatt gaattatggc acaaaagtat atgtatattc
     6721 tatcagtaat gggtgggcca aaatttctct tggcggcatt taccgttatg ttagtgccga
     6781 ttaccttcgg gagctttaag gaaaaacatt taatataaac gaggcatagg taaatagctg
     6841 tatgggctgc cgcactgaaa agtttggtgc ggcagcactt ttatttactt ttttaattga
     6901 aactacaaat ggacaaattc taaaaaacgt cccaaaaaca gtattctgtg tttgggttat
     6961 aaagacaaat ttaaaatata tagatatttc cggtggttcg tggtatgata aaaatagaaa
     7021 caaaagtgct atttcaagaa agggtgatgg ttatggcatt ggcacaggca acaaaatccc
     7081 atgaaccaac ttatacaatc aatgatgcaa tggatgttct tttgtcaagg ctggatgaag
     7141 ccattgatga tatggaaagt gacagagtgc agatagtgga agaagcatgg gcagaaattg
     7201 atgcaatata aggggtacgg atggaaaaaa gaaaatacaa agttgtaatt gcccagagcg
     7261 gcaagctgga tgtgaaggaa aaaagaaata tatccttcag caatttaaat accgggagta
     7321 tgcagaggat ttttcccaaa agattaaaaa gcggttcttg cacttgacac acttcctacc
     7381 agatataata caataggctt ccgatatcgt ggctatgata tttacatgaa atatactgcc
     7441 tgttttttaa cgccattgga attgttagaa agaaagatta aaataagaga caccagcaat
     7501 caatacgctg atgtctctta ttaatattac ctgattgttg ataaataatt tactttgtat
     7561 cctgcagtgc gagataacct tcttcgcctg tacggatctt aacgacattt tcaatgtcat
     7621 atacaaatac tttaccatca ccaatctgac cggtatggag gactgccttg gcagtttcga
     7681 taactttctg tacaggtacg agacttacaa caatctcaat tttgacctta ggaagaagat
     7741 tcatttccat ctcaacacca cgatagtagg atggagcacc tttctgtaca ccgcatccga
     7801 gaacgttcgt aatagtgata cctgtaacac cgatctcatt cattgcctgc ataaattcat
     7861 caagcttatt ctgacgggtg atgataacaa cttttgtaag cttatgaacg ccttctttcg
     7921 gaagttcagg aactgattca gcaggagcag aaggtctggc tgtgacaaca ggagctttta
     7981 tggaagttcc cataggagtc ggaacgccag ccattgcgaa accgtcataa gcacttgcaa
     8041 gaccatgttc tttggagtca agacctgcga tctcttcttc agctgaaaca cgaagtccga
     8101 ttgtatgctt gattacctgg aagataattg tcatagtaac aacaacccat gcgattgtga
     8161 tgatcatacc tgtgaactga acaccaaatc cgtggaagcc gccgcctgta agaagtcctt
     8221 tccagtctgt gcctgatcca tcggagaaaa gaccaactgc aagagtaccg aaagcaccgt
     8281 ttaaaccatg aacaccgaca gcaccaacag ggtcatcgat tttcaggact ttgtcaataa
     8341 attcaatacc aaatactacg ataaaaccgg aagcaatacc gatgattgct gcggatgtag
     8401 gagaaactgt gtcgcatcct gccgtaattg ctacaagtcc tgcaagagaa ccgttcagag
     8461 acatggaaac atccggtttt ttgtaacgta cccatgtgat gatcataaca gttacagttg
     8521 caacagctgc tgcaaggtta gtagtaacga agattttacc tgcacttacg attgcatcgc
     8581 cttccatact tactgtggaa gcaccgttaa atccgaacca gcagaaccag aggataaata
     8641 cacctaaagc accaactgta aggttgtgtc cagggatagc ttttgatttg ccgtcctttg
     8701 tatatttacc gatacgaggt ccaaggatga tggcaccgat cagagctgcc acaccaccta
     8761 ccatatgtac tgcacaggaa cctgcgaaat cgtggaatcc catctggctg ataaatccac
     8821 cgccccagat ccagtgtccg gataccggat atacaacaag actgatcata aggctgtaga
     8881 cgcaatagga aagaaacttg gtacgttctg ccattgcacc ggaaacaatt gttgcggatg
     8941 ttgcacagaa tactgtctgg aagattaaga atgcccagaa aggaactccg tcaggaagca
     9001 ttcctgaacc atagtgtgct tctgttgcaa taccaccgat ctttccgata aatccattac
     9061 ctgcaccgaa catcagaccg aagccgacca gccagaagac cggggttccg atacagaagt
     9121 ccatcaggtt tttcataata atgttacctg cgtttttggc tcgtgtgaag cctgtttcta
     9181 ccattgcgaa tccggcctgc ataaagaaga ccagcgcggc gccgaccagc acccatattg
     9241 tgtttactgc ggaaaattcc ataataatat tcctccctca taaaaatttc ctcatatttt
     9301 ataaaatgca aaaagcgcga tgcctggaaa tgtagccagt tcatcgcgct tttgcgaata
     9361 taaaatccat atttatagtg tattgcataa ctgatgtaat agaaaagaca tttcgtatga
     9421 ctgtatgcaa tgcagtttaa aatcaaaatt atatgtaaaa caggggaaca tcaaaatatc
     9481 gtgtgattaa tggatgagga aatcgataat gaattatgaa gtagagttca taaagatatt
     9541 cccctgttat tacctgttaa ttaaacggaa aacagaagct tgtcatatgt aggatatgga
     9601 agcagtgcat ccggaatcag agtttctgct gcatctacag actttctgag ttcatccata
     9661 tcagaaagaa caactgtctg gtatgctttt gcattagcca gaggatcttc tgtagcaagc
     9721 gctttggcag tatctgcttt taaggtctca agacctgtgg aaatctcatc agcaagctgt
     9781 gacagctctt tgatcagttt tccttcagaa gctgtgctga catctgaaac aactgatttt
     9841 ttagcaacag cagtagctgc aactttgtcg atatatgcga atacagatgg aaggaaatcc
     9901 ttctgtacca tttcaaccat agtattggac tcaatgttaa gaatcttgga ataggattcc
     9961 agccagatct cataacggga ttcaatttct tcttttgtga agatatgata tttggtaaag
    10021 agttcaatat ttttatctgc gatccactga ggaagagcat ccggtgtaga tttcaggtta
    10081 aagagacctc gtttctcagc ttcttcgatc cattcatctg tataaccgtt tccattaaag
    10141 ataacacgtt tatgatcaat aattgtcttc ttgatcagct cgtggattgc atcctccatc
    10201 ttgtcttccg gtacatcttt taactgttct gcaaactggt gaacacactc agcgacagca
    10261 gtgtttaaga taatgttcgg gtttgcaaca gaagcctcgg aaccaagcat acggaattca
    10321 aatttgtttc ctgtaaatgc gaatggtgaa gtacggtttc tgtctgtatt gtcttttacg
    10381 aaatgtggaa gtacttttgc accgatatcc atctggactg cgcggcttcc tgcaaagtat
    10441 tcatcatttt cgatagattt taatacttct gtcagttcat cgccgaggaa tacggataca
    10501 acagcaggcg gagcctcgtt tgcaccgaga cggtgatcat ttcctgcact tgctacagaa
    10561 atacgaagta catctgcata ttcatcaact gctttgataa cagctgtcag gaaaatcagg
    10621 aactgtgtat tttcagcagg tgtttttccc ggatcaagga tatttacacc agtatctgtg
    10681 atcatagacc agttgttgtg tttaccgctt ccgttgattc cctcaaatgg tttctcatga
    10741 aggaggcata caagtccatg cttgtcggca actttcttca ttacttccat tgttaactgg
    10801 ttgtgatcaa ccgcaacgtt tgttgtatcg aatacaggag ccagctcatg ctgtgcagga
    10861 gcaacttcgt tatgttttgt tttggcagga ataccaagtt tccagagctc tacatccagg
    10921 tcatgcatat aagctgcaac acgaggtttc agagcaccga agtaatgatc ttccatttcc
    10981 tgacccttag gagcaggagc accgatcagt gtacgtccgc agaatacaag gtcttttctc
    11041 tgcttgtata attccttgtc taccaggaag tattcctgtt caggacctac agttgtattt
    11101 acgtgtttga catctttatt acctattata tggagaagtt ttgtagcttc tttatcaagt
    11161 gtctgcatgg aacgaaggag aggagtcttt ttatcaagag cttctccgct gtaggagcag
    11221 aatgctgtag gaatgtaaag ggttccgtct ttgatgaatg ccggtgatgt cggatcccat
    11281 gctgtatatc ctcttgcctc gaatgtggca cgaagaccgc ctgacgggaa actggaagca
    11341 tccggctcac cttttacaag ttctttacct gagaaatcca tgatcacctg accatctcct
    11401 gtaggagaaa tgaaactgtc atgtttctct gcagttacgt ttgtcattgg ctggaaccag
    11461 tgagtataat gagtggcgcc gttctcggta gcccattctt tcattgcaac agcaacggag
    11521 ttggcaacat caagttcaag gtgtgtaccg ctctcgattg ttttctttaa tgctttgtac
    11581 atgtcttttg gcagtttact tctcattact ttgtcgttga agaccaggct gccgtacagt
    11641 tcagggatat tctgtgccat ataggtactc tcctttcggt ttgcaatatt ttctgaatat
    11701 gtgtagtgcc gctacagatc accattgtga ctgcctgcgg ttttcgtctc atagaaaatt
    11761 cctcatcgaa cattttctat gaaacgaaag ttttataaaa cgaaaaaggc gccctggatg
    11821 agatctctgt agatctttcc aaagcgcctt tgctttatgt gctgtactat aaacgaaatg
    11881 aaaacagatg tcaagcactt tttttgaaaa aattcagaaa aaatttttga gatatggcaa
    11941 aaaaaggata ggttgacaaa tttgtttcta ttattataat ttgattttgg aacccaccaa
    12001 acataagaaa acaatgtcag cgggttttga aagtaaagtt aaagtcagac aagagaatac
    12061 gatcggagga aatcagatgg ctggaataaa agaagagtgc ggcgtctttg gaatttatga
    12121 tctggatggc ggcaatgtag ttccgtccat atattatgga ctgacttccc tgcagcacag
    12181 aggacaggaa tcctgcggac ttgcagtttc tgatactaag ggagagcgtg gaaatgtgaa
    12241 gtttcataag gatctgggac ttgtaagtga agttctcaga caggatgttg tccgtaaata
    12301 tgagggggat attggtattg gtcatgtaag atattccaca acaggagctt ctgttgcaga
    12361 gaatgcacag ccccttgttt tgtcttatgt aaagggaact cttgcacttg cacataacgg
    12421 aaatctggtt aatacaccgg aactgaaatg ggaactgatc cagaatggag cgattttcca
    12481 tacaactaca gattcagagg ttattgcgtt ccatatcgca agagaacgtg tgcattctaa
    12541 aacagtagaa gaggcagtgc taaagactgc aaagaagatc aaaggtgcat atggtctggt
    12601 agttatgagc ccgagaaaac tgatcgcagt ccgcgaccca tatggactga aaccattgtg
    12661 tctcggtaaa agaggaaatg cttatgttat tgcttctgag agctgtgctc tgacatctgt
    12721 aagtgcggaa tttatccgtg acattgagcc gggtgagatt cttacgatca caaaagacgg
    12781 actgaagtca aataaagagc ttgcgtctgc tgctgcaaaa cgcgcgcatt gtgtgtttga
    12841 gtatatatat tttgcaagac ttgacagtac cattgatggg gtgaaggtct atgatgccag
    12901 aatccgcggc ggtaaatctc ttgccaagtc ttatcctgta gaggcagata ttgtaacagg
    12961 tgtaccggag tccggactcc ctgctgcaaa gggatactcc gaagcatcag gaatcccgtt
    13021 tgcatttgcg ttttataaaa acagctatat tggaagaaca tttatcaaac cgactcagga
    13081 agaacgtgag tccagtgttc atctgaaact gagtgtgctg gaatctgttg taaaagataa
    13141 gaggattgtt ttggtggatg attctattgt tcgtggaaca accattgcaa acctgatcca
    13201 catgttaaaa gaggcgggag caaaggaagt gcacgtacgt atcagttcac cgccattttt
    13261 acatccatgc tatttcggaa cggatgtgcc gtcaaatgat cagctcattg cagccagcca
    13321 cagcacggag gaaatctgta aaatgatcgg agcagattct cttggctaca tgcagacaga
    13381 ttatctggaa ggcatggcgg gcggcctgcc cttatgtaag gcatgcttcg atggaaatta
    13441 tccgatggag attccggatt atacaaatgc ggagtttgca gatattgtga agtgttaagt
    13501 cgcaaaaatt cataaaaaat gcagaaacct gtcgataata tatggaatca atctcatata
    13561 atggtaaaac caatatagaa tgaaaccata cataatgtat aaaataatgc tgtgaaaaca
    13621 tatataaacg aataaaatgc acaatagaac ccctgtgctt tatgaaaatt ggataaattt
    13681 aaaaacttga caaattctga aatgtggaac ataatatggg cgtctgatag aaaaaaacaa
    13741 agaatgtttt cagaaagggt gatcacgatg tcacagagta aaatcaagtt aaatgcaact
    13801 gaagaggtgc aggaatttgt gaatgctgca agcagatgtg attttgatat tgatgtttat
    13861 tacaacagat ttttaattga tgccaaatca atccttggtg tacttagtct ggatctgacc
    13921 agagaactta cagtagactg ccacggggag agccgggaat ttgatcgtac attgaagaaa
    13981 tttgcagttg cataaatttt gcatttttat aaccgaataa ttattgcaga gaagacgggt
    14041 ctggaagatg aacttctaca gattcgtttt ttctgtatta tgactgtgtt cagagtaatt
    14101 ccataaaata taactgcttc atagtttatc agaaggaact tatttgattt gtttttgctt
    14161 aaaaacggga aattcattat tgacaaacga aaaaaaatgt tttatagtat agcatatttt
    14221 taaagaaagc caattgaaca tattattata gaagatatga tgatctgaca aaggcgtcag
    14281 atgcagaata ccagatgggt caagtgccct ctgatagctg tatctgacgc ttttttatta
    14341 acaaaggatg atggaggagg aaatcaaaat ggcagtgaaa tacgtatttg ttacaggagg
    14401 agttgtttcc ggtctcggaa agggaatcac agctgcatct ctggggcgtc ttctgaaagc
    14461 gagaggatac caggtaacca tgcagaagtt tgatccttat atcaatatcg accccggaac
    14521 catgaacccg attcagcacg gagaagtttt tgtaacagac gatggtacag agacagacct
    14581 ggatctggga cattatgaga gattcattga tgagagtctt gataaaaatt ccaatgtgac
    14641 aaccggtaag gtttactggt ctgttcttca gaaagaacgt cacggggatt tcggcggggg
    14701 taccgtacag gtaattcctc atattacaaa tgagattaag agccgtttct accgcgccaa
    14761 atcaccggag gaaaacaaga ttgccattat cgaggtggga ggaacagtcg gtgatattga
    14821 aagccaaccg ttcctggaag caattcgtca gttccagctc aatgtgggac atgacaatgc
    14881 aatcctgatc cacgtaacat taattcctta tttaaaggca tctgaagaac tgaaaacaaa
    14941 acctacacag gcaagcgtaa aggaacttca gggaatggga atccagccgg atgtactggt
    15001 gtgcagaagt gaacatgagc tgacagagga cattaaagaa aaaatcgctt tattctgcaa
    15061 cgtacctgta tcacatgtac ttcagaacct ggatgtggaa tatttatatg aagctcctct
    15121 tgcaatggaa agagagaagc ttgcagatgt agttctttca agtctccgtc tggaaaacag
    15181 aaaaccggat ttaagtgact gggaggaaat ggtagaaagt ctgagaaatc cgaataaaac
    15241 agtaaagatc gcaattgtag gaaaatatac acagcttcat gatgcatatc tcagtgtagt
    15301 agaggcactg aaacatggtg gaatttcctg cagagccaaa gtagagcttg actggattga
    15361 ttccgaagaa ctgacagaga aaaatctgga tcagcagctt cacaatgtag atggtatcct
    15421 ggttccgggt ggtttcggaa acagaggtac agaaggaatg atcctggcag cacagtatgc
    15481 aagggtacat aagattccat atcttggaat ctgtctggga atgcagatgg caatcgtaga
    15541 atttgcccgc catgtacttg gatacgaaga tgcaaacagt attgaactga atccggagac
    15601 aaagcatccg gtaattgcat taatgccgga tcaggaagat atcgaagata tcggtggaac
    15661 cttaagactt ggaagttatc catgtattct tgcagaaggt tccagatcct atgaactttt
    15721 tggtaaaaaa gaaatccaag agcgccacag acatcgttat gaagtaaata atgcattccg
    15781 taaagaactc caggagaagg gaatgaatat tgtaggaact tcccctgata atcatatcgt
    15841 a
//
