LOCUS       c00145_gnlPro..        25206 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GAGFMGDE_145.
ACCESSION   c00145_gnlPro..
VERSION     c00145_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 00:36:58
            Original ID  :: gnl|Prokka|GAGFMGDE_145
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 57277
            Orig. end    :: 82483
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25206
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[67277:72483]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15206
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..25206
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25206
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             1402..2286
                     /locus_tag="ctg145_58"
                     /transl_table=11
                     /translation="MEQRIKGTTGLMALIGSPVGHSGSPAMYNFSFRYHNLDYAYMAFD
                     IKEDQVPAALDAIRLFKMRGANVTMPCKNEVAKHMDELSPAARIIGAVNTIVNEDGKLV
                     GHITDGIGFVRNLKEHGVDVKGKKMVVLGAGGAATAIQVQCALDGAESISIFNPKDPFF
                     ARAESTAEKLSKETPDCKVSVFDLEDEAKLKEEVANADILVNATLAGMKPHEELTLIKD
                     KSMFRPDLVVADVVYNPAETRMVKEAKEAGCKLAIGGKGMLLWQGAAAYKLYTGLEMPT
                     AEYQKFQEENENK"
     CDS             2307..3506
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 49.7; E-value: 8.6e-16)"
                     /gene_kind="transport"
                     /locus_tag="ctg145_59"
                     /sec_met_domain="MFS_1 (E-value: 1.2e-15, bitscore: 49.7,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQKTNKMLIFTSLAAYFTYFIHGIGASILGQYKPEFAAAWGAKP
                     LADGTLDVSMVVSVIAALGLGRLISLPFSGPLSDKYGRKLSGIIGVLCYVAYFFGMANS
                     TSMAMGYAFAVIGGIANSFLDTCVSPTCMEIYVNNPSVANLFTKFSICLSQFLLPFLIG
                     IVASANMSYKTIFIVAGIAILIDGILILILPFPAREKAVQAKADKKKSGHKISPAAIAA
                     ILIGFTSSSTFMLWLNCNQELARSYGMADPSKIQSLYALGTATAILATAAFIKKGLKEI
                     NVLILYPLISTIMLLLCYFIQAPFICLIGGFVIGYAGAGGVLQLAVSTTAEFFPENKGT
                     ATSLVMIASSIANYTILSLAGYITKVGGSSAPRMILLLNMAVTIVGILLALFVKKNRNQ
                     "
     CDS             3798..5156
                     /locus_tag="ctg145_60"
                     /transl_table=11
                     /translation="MAHTRTQRRENELPYIPFGPFQIRLPFIHYKIESVEFIQGLILGV
                     TALAAVPYLEQYLGLPYELAWSCVIIETFLYLLHSLLGDPVVPGWITPTLPLTIVFLEG
                     FPMGEERIQAMIALQMLVGLVFIFMGVTRLADKFVHAVPNSVKGGILLAAPVTVMAGQL
                     GENGNMHKYPLAIVAGVGLLILISFSDKYQEKRKTNKFLDLVARYGNLFPYLIAMVVGL
                     LVGELDAPGLEIGTFIKIPQFKDIIDQVSIFGVGIPPASMFIKALPLALVCYVIAFGDF
                     VTTETLVSEARQARDDEYIDFNSSRSNLVSGLRNLILSIIAPFPPLSGPLWVGMTVSVS
                     MRYKEGKKAMKSLLGGMASFRLATFLSVLIIPVVSFFRPIFGVGSSITLMFQAFVCARI
                     GMDYCKSDRDKMIAGVMAAVLATQGTAWASAWALAVGFGLNIFLSNWNPFEKK"
     CDS             complement(5337..6098)
                     /locus_tag="ctg145_61"
                     /transl_table=11
                     /translation="MNTVQVKNTVIGEGRPKICVPIVGKTKTDILEEAKKITTLPVDVV
                     EWRVDWFDDVFATEKVLETVKELQEVLKDIPVLLTFRTSKEGGEKEISVSDYAALNIAA
                     AQSGYVDLIDVEAFTGDDIVKTIIDAAHEAGVKVIASNHDFFKTPEKEEIIRRLRMMQD
                     FGADIPKMAVMPTCKQDVLTLLSATLEMSEKYADRPIITMSMAGTGVVSRLTGETFGSA
                     LTFGAASKASAPGQVGVHELKQVLDIIHSSL"
     CDS             complement(6367..7245)
                     /locus_tag="ctg145_62"
                     /transl_table=11
                     /translation="MAERITGHTELIGLMAYPIRHSSSPAMQNEAFAKLGYDYAYLAFE
                     VGADEIEDAVKAIRTLKMRGSNVSMPNKTLVGKYLDELSPAAELCGAVNTIVNDNGHLT
                     GHITDGIGFMSALKDNDIDVIGKKMTIVGAGGAATAIEIQAALDGVAEITIFNRKDEFW
                     DRAVSTVEKINTKTSCHAVLYDLADLDKLKTEMDDSYIFVNATGVGMKPLEGQSVVPDK
                     SYFRPELIVIDVPYSPLETKMRSMAKEVGCKTMNGLGMMLFQGSAAFELWTGEPMPIEH
                     MKEILHISYDD"
     CDS             complement(7285..9282)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) baiH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_63"
                     /sec_met_domain="baiH (E-value: 2.1e-143, bitscore: 471.4,
                     seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSNYQHIFTPLTVKNMTIKNRIVMMPMGTNYGEQNGEMSFLHIN
                     YYKERAKGGTGLIIVENASVDSPQGSNGTTQLRIDHDNYLPRLYKFCEEIHKYGTCIAI
                     QINHAGASAVSARTNMQPVSASDVPSKEGGEIPRTLSVEEIHHIVKKYGEAAKRAQAAG
                     FDAVEIHAGHSYLISQFLSPLTNKRTDEFGGSVENRTRFCRMVIEEVRKQVGPFFPIML
                     RLSADELMEGGNTLEDTLEYLEYIQDEVDIFDVSCGLNGSIQYQIDANYMKDGWRSYMP
                     KAVREKFGKPCISMGNIRNPKVAEQILADGDADLIGMGRGLIAEPAWVNKVATGRECDL
                     RKCISCNIGCAGNRIGFNRPIRCTVNPAVLEGDVYKNQKVNKNCNVVVIGGGTAGLEAA
                     CTAAEVGCNTFLLEKGETLGGLASVISKIPAKKRLADFPNYLIHRAAQLENLYIFTNTE
                     GTPENIRKFHPNLIVSSTGSAPLLPPIKGLHDRIDKEGSKIASILGMINHINDYPEDMT
                     GKKVVVVGGGAVGLDVVEFFAARNAEISIVEMMDQIGRDLDPVTKNDMKDQMKKHHVAQ
                     LTKTALQEVKDSSFLVKDVEGERELPFDYGFVCLGMRAQGQPFTELSDAFVSDDVEILN
                     IGDSKRARRIIDGTLEGRNILNTLTQMGYL"
     CDS             10001..11437
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_64"
                     /sec_met_domain="CT_Vparvula (E-value: 9.2e-136, bitscore:
                     445.7, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNATQSLAGTRITSLLDANSFVEIGQGVTARSTDFNMTANKAPS
                     DGVITGYGVIDDKLVYVYSQDASVLNGTVGEMHAKKITRLYDLAMKTGAPVIGLVDCAG
                     IRLQEATDALEAFGQIYLKQTLASGVIPQITAIFGTCGGGMAVIPSLTDFTFMESKKGK
                     MFVNTPNALEGNNTDKCDTAAADFQSKETGVIDGVGTEDEILGQIRSLVSLLPSNNEDT
                     DNYTECTDDLNRVCADLANCAGDTAIALSQIADNGEFFETKADYAKDMVTGFIRLNGAT
                     VGAVANRSEVYDAEGKKTETFDGSISARGARKAADFVKFCDAFDIPVLTLTNATGFMAT
                     LCSEKMMAKSVGELVAAFADATVPKVNVIIGKAYGTAYVAMNSKSIGADLVYAWDNAEI
                     GMMDASLAAKIMYADADAAELNEKAAQYRELQNGVASAAARGYVDTVISPADTRKYVIG
                     AFEMLFTKREDRPSKKHGTV"
     CDS             11452..12207
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_65"
                     /sec_met_domain="OAD_gamma (E-value: 6e-27, bitscore: 86.6,
                     seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKMIKKITSVFMTFLVMAALVIGSTSVVFAADKVDDTVKSTLVTT
                     AEGLTDAIVQLKDEEIENYMSSGDDFTTSAMQSWQTSKDELGAKKDSNGETTVTFKDDQ
                     YTVTVPLKFEKAEANFVYVFDSQGTPTSMSVDVQYGMGKTLQRAGLNTLMGIGTVFVML
                     ILLSLLISLFRFIPNPEAKKAAEAKAAKAAKEAEAAAIAQTAPAQAEENLADDGELVAV
                     IAAAIAAAEGTTTDGFVVRSIRKVKRNRR"
     CDS             12235..12603
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 63.1; E-value:
                     5.3e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_66"
                     /sec_met_domain="Biotin_lipoyl (E-value: 7.5e-20, bitscore:
                     63.1, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYTITVNGTAYEVTVEETGSVSAPAAAPKAAPKAAPAAAPKAA
                     APAAGAGAVKVTASVPGKVVKVAASVGQAVKAGDSVIILESMKMEIPVVAPQDGTIASI
                     DVAEGASVENGDTLATMN"
     CDS             12620..13768
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_67"
                     /sec_met_domain="OAD_beta (E-value: 9.5e-156, bitscore:
                     510.5, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYVTETLSNLIHQTAFFNLTWGNYLMIAVACVFLYLAIKKGFEP
                     LLLVPIAFGMLLVNIYPDIMANPEDMSNGVGGLLHYFYILDEWSILPSLIFMGVGAMTD
                     FGPLIANPISFLMGAAAQLGIYAAYFLAIFLGFNGKAAAAISIIGGADGPTSIFLAGKL
                     GQSALMGPIAVAAYSYMSLVPIIQPPIMKLCTTEKERKIKMDQLRPVSKLEKILFPIVI
                     TIVVCLILPTTAPLVGMLMLGNLFRECGVVKQLTETASNALMYIVVILLGTSVGASTSA
                     EAFLNADTLKIVVLGLVAFAIGTFGGCMLGKLLCKLTHGRINPLIGSAGVSAVPMAARV
                     SQKVGAEADPTNFLLMHAMGPNVAGVIGTAVAAGTFMAIFGV"
     CDS             13794..15206
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: PYC_OADA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: HMGL-like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_68"
                     /sec_met_domain="HMGL-like (E-value: 3.1e-46, bitscore:
                     150.5, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 3.5e-58, bitscore:
                     189.1, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELEKKPVKIVETILRDAHQSQIATRMTTEQMLPIVDKLDKVGY
                     HAVECWGGATFDASLRFLHEDPWERLRKLRDGFKNTKLQMLFRGQNILGYRPYADDVVE
                     YFVQKSAANGIDIIRIFDCLNDLRNLQTAVSAANKEKAHAQVALSYTLGDAYTLEYWTD
                     IAKRIEDMGADSICIKDMAGLLLPNKATELVTALKETVKIPIDLHTHYTSGVASMTYLK
                     AVEAGVDIIDTAMSPFALGTSQPATEVMVETFKDTPYDTGFDQKLLSEIADYFRPIRDE
                     ALDSGLLNPKNLGVNIKTLLYQVPGGMLSNLTSQLKEQHAEDKFYDVLEEVPRVRKDLG
                     EPPLVTPSSQIVGTQAVFNVLMGERYKMVTKETKDILLGKYGATVKPFNPEVQKKCIGD
                     EKPITCRPADLLDNELEKLESEMAQYKEQDEDVLTYALFPQVAMDFFKYRQAQKTKVDE
                     KAADKKNGAYPV"
     CDS             15318..16766
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HI0933_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_69"
                     /sec_met_domain="HI0933_like (E-value: 9.2e-128, bitscore:
                     418.8, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMPEVHIYIDRSEAETWNHDEIDNLQGKINTGEYSMSKVIIIGGG
                     AAGMMAGVFAARNHHEVHILEKNEKLGKKVFITGKGRCNVTNACDTEELFPAMMSNPKF
                     LYSSFYSFTPQDVMEFFEKAGVPLKVERGNRVFPQSDHSSDIIRALERELKKAGAKIHL
                     HTAVREIVKKPVTDSANTLESEAALTESGSDAGKGRKGKKSPDIPQEKIAGVILTDGTF
                     MEGDAVIVATGGFSYQSTGSTGDGYRFARELGLKVTDIAPSLVPLKTKEDYVPKLQGLS
                     LKNTGLTIKNGKKVLYEDFGEMMFTHFGVTGPMILSASAHIGAKLAKAPNGELSAYLDL
                     KPALTKEQLDARILREFEAGPNKQFKNVIGVLFPSSLTPVMIELGGIPAEKKIHDISRE
                     ERQHFIDLIKAFPFTITGMGEFKEAIITRGGVSVKEINPGTMESKKISGLYFAGEVLDL
                     DAVTGGYNLQIAWSTAYLAAQAIQ"
     CDS             16925..17596
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytidylate_kin"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_70"
                     /sec_met_domain="Cytidylate_kin (E-value: 2.7e-77,
                     bitscore: 251.7, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGCNIAIDGPAGAGKSTIAKKVAKELSFIYVDTGAMYRAMALYLL
                     NHGVNGENQEEIEAVCSGADISIEYKNGEQIVILNGENVNAMIRTEQVGNMASKSSANP
                     KVRAHLLKLQRTLAEKNDVVMDGRDIGTTILPNAEVKIYLTASADTRAKRRALEYEQKG
                     ESFDLDQIRKDIIERDERDMNREISPLKQADDAVLVDSSEMGIDQVVDAILDVYNKKIQ
                     K"
     CDS             17785..18663
                     /locus_tag="ctg145_71"
                     /transl_table=11
                     /translation="MKVKVAETAGFCFGVKRAVDKVYELIGTEQKPIYTLGPIIHNEGV
                     VADLEARGVHVITEADLDSPDDTLQNGTVVIRSHGVGKAIYDKLKEKNISYVDVTCPFV
                     LKIHRIVEKESLAGNHIIIIGDKDHPEVQGICGWCQGPYTVIRNKEEAEVFVPPKGKKI
                     SIVSQTTFNYNKFKDLVEILCKKRYDNNVLNILNILNTICNATEERQREAKNIAGEVDT
                     MLVVGGRHSSNTQKLFEICKKECGNTYYIQTPVDLDSEMFQCSSYVGITAGASTPNKII
                     EEVQEHVRIKF"
     CDS             18644..19720
                     /locus_tag="ctg145_72"
                     /transl_table=11
                     /translation="MSELSFEQMLEDSVKTIRNGEIVQGTVIDVKEDEIILNIGYKADG
                     IITKNEYSNDASLVLTDAVHVGDTMEAKVLKVNDGEGQVTLTYKRLAAEKGNKRLEEAF
                     ENQEVLKAPVTQVLDGGLCVNVDEARVFIPASLVSDTYEKDLSKYADQEIEFVITEFNP
                     RRRRIIGNRKQLLLAEKAEKQKELMEKIHVGDTVEGTVKNVTDFGAFIDLGGADGLLHI
                     SEMSWGRVENPKKVFTVGDKVKVLIKEINGEKIALSLKFPEANPWLTAAEDFAVGNVVK
                     GKVARMTDFGAFVELAPGVDALLHVSQISREHVAKPADVLSIGQEIEAKVVDFNGEDKK
                     ISLSMKALEAPAEEATEE"
     CDS             19868..20614
                     /locus_tag="ctg145_73"
                     /transl_table=11
                     /translation="MSIKGIYDIHCHIVPGVDDGATDIGETVKLLRMEYEQGVRTVIAT
                     PHFRFRMFETPAEKVREQFRLVEKAASEISPDLHVYLGCEFHANMEMLPMLREQKVMTM
                     AGSRYVLTEFSHNSEESYIRERLGALLSGGYKPIMAHIERYEATRNSLDFVEELADMGV
                     YMQINADSITGKDGFFTKRYCNKIMKDGLLHFVGSDCHNSTKRSSRIGEAYRMVSAKFG
                     QDYADELFIHNPAEILKQKQKHEATD"
     CDS             20755..21534
                     /locus_tag="ctg145_74"
                     /transl_table=11
                     /translation="MLDNLNSNFESSKAQRPDANDDEVEIDLLEIFYALKKKILLVLMV
                     ALAGGCIAAAYTQFLMTPIYSSTSSILVLSKETTLTSLADLQLGASLTSDYTVLITSTP
                     VMEQVISDLDLDMTAEQLKGSVSINNPTDTRILEITVNNTDSKMAKKIVDEIANVSSSY
                     IGDKMEVIPPKIIEVGKIATVRTSPSVKKNAALGFLLGFLACAAIVVVYAVMDDTIKTE
                     EDIEKYLGVSVLAKVPDRKDFINSKNRKSKNKNKKHH"
     CDS             21556..22266
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_75"
                     /sec_met_domain="CbiA (E-value: 2.6e-08, bitscore: 26.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLNLTDKRNPDYFYSEAIKTLRTNIQLSGQSIKTILVTSCYPN
                     EGKSDIVLSLAQELGSIGKKVLLLDADIRKTAYAGRLGVEEEVKGLSQLLSGQVGLQEV
                     IYSTNFPNMDIIFGGPSAPNPSGLLSENIFKVFLKEIREYYNYILIDTPPIGTVIDAAV
                     IGRCCDGAVFLIEPGNVRYRDAQKAFKQLERSGCRILGAVMNKIDTSDDKYYSSYYKHY
                     GEYYRRSDEEAQIK"
     CDS             22300..23292
                     /locus_tag="ctg145_76"
                     /transl_table=11
                     /translation="MINDKGEFGKVSKIRNKKIKKTNILLGFICILLAVLLGFILVTSY
                     KSEQKESRHLSEIADDQQSGIEDYEAVKERAKELEEVSSEEAEDTEDIKSKNTEDTKDT
                     EKTDTADTEDADKTEDTKDKTTAASGIVCWGDDLINGEESNTYSYMTVLQKLLTDNGYN
                     MTVVNKTLQGGGTLSMMKMAGVSDETIQSYITRHQQAANGAQLNVTETGIRDLTEEQTT
                     RNDMDCIPVIFMGYYGGWNHDPAELADQQEQILNTFQNKDQFIVVGTRPMDGSVTSEAL
                     DQVLSQKWGEHYISLADVTAQPSSTYEAQQAMAEAILQKLQELNYISKN"
     CDS             23329..24360
                     /locus_tag="ctg145_77"
                     /transl_table=11
                     /translation="MKKTTRKAIRQRKICMLLIIILIIVLSILGGGYYLLSQKNAASSK
                     AGGQNSDSRNQTDLNQNSDTVEYKGEIYKYNNHLSNYLFLGIDTREAVDTYQSQADAGQ
                     ADAIFLVSMDRATEKIKVLFIPRDSMTRIEVFNPYGQSLGETTDHLNIQYAFGDGKEKS
                     CELMKTAVSDMLDGLPIQGYCSMNMDGISVITDFVGGIQLTIPDDSLADVNSEYKKGAV
                     VDITGETAEQFVRYRDIDKTQSALVRQERQKTFLQALVQKAQEKAGEDAGFVTGLYDSV
                     KSYTVTNMGNDIFAKLLAASQNGITDTETVPGEGTHGENFDEYHIDEDALSDLIISMFY
                     EKI"
     CDS             24501..25127
                     /locus_tag="ctg145_78"
                     /transl_table=11
                     /translation="MKIAKKFMTLALVAALGVGCATVGVGAAPSNTSDLAAVAPSKTSE
                     ITVDSKQSSIYEVVKELEKTQGFADLQAKYKDLADAFKKINDGTMKMEDFIKVLKSLSV
                     DEADKADLEDAIAKLEGKMIVTFVYEFNVLKPEEAKPNDDGTYEVKLNVPSLTDTMEGI
                     QLWVYSKDGTKKFVVIDPVNIDKEGKTLTVTLNDGDFFMVIADAK"
ORIGIN
        1 catgtatcca gagctgttca catccgcgat gaatttatgt gggcaccgac agttacacac
       61 ggcggtttct ccgcttctca ggtagaagag atcaaacgtg ccgtatctat cccggtgatc
      121 acagtaggac gttatacaga accgcagttt gcggaattaa tggtaaaaga aggacgctgt
      181 gacctggttg cattcggacg tcagagcctt gcagatcctt atatgccatt aaaagcgcag
      241 gaagaaagac tggaggatat gatcccatgt atcgcatgtc ttcagggctg cgtggcaaac
      301 atgtatgcag gaaaccctgt atgctgtctt gtaaacccat tccttggaca tgaagctgag
      361 ggtattgctc ctgcagaaaa agctaagaaa gtaatggtaa tcggcggcgg tgttgcaggt
      421 ctttgcgctg catttatcgc acaggaaaaa ggtcatcagg taacacttta tgaagcaagt
      481 gataaacttg gcggaaacat gcgtcttgct gcttatcctc cgggaaaagg cgacatcaca
      541 aacatgatcc gcagctatat cgtacgctgc cagaaagcag gcgtaacaat taaaatgaat
      601 caggaagtaa ctctggatct tatcagggaa gagaaaccag acagcgtaat tgttgcttcc
      661 ggttccagaa cactgatcct tccgatcgaa ggtatcgaca atcctgcaat tatccatggc
      721 tctgatctcc ttgacggaaa gagagcagca ggaaagaaag tactggttgt aggtggcgga
      781 atggtgggat gcgagacagc agcattcctc ggtgagcaga accatgatgt aacagtcatt
      841 gagttcagag acactgtagg tgccgacgtg atccacgagc atagagttta cctgatgaaa
      901 gatttcgaag attacaagat caaagagatc acaggtgcaa aggtatgcaa attctatgag
      961 gacggcgtag agtacgagac agcagacgga cagagacatg aatccagagg atatgattct
     1021 gtcatccttt ccatgggatt cagaaactac aacccattcg gcgaagagat caaagctatc
     1081 gtaccggata cctatgtgat tggcgatgcc acccgcgcaa gaagagcact tgatgctacg
     1141 aaagaagcgt atgaggtagc ttccacatta tgatgatatc agggtcaaaa gttcaaaaag
     1201 tcgttcgtgc ttgcacgata agatttttga acctgggacc cgccaaacat gagaaagcag
     1261 cgatttacgc agtaaatcag cgaatttcga atcttataat ttattcgttt tatagttgca
     1321 gttaagagac gctgtatgat attatcagcg gacagcagct tgaaaatgat tttacaaaaa
     1381 aattcaggag gcaaacagga aatggaacag agaattaaag gaacaacagg attaatggca
     1441 cttatcggaa gcccggtagg acactcagga tcaccggcaa tgtataactt cagcttccgt
     1501 tatcacaacc ttgattatgc ttacatggcg tttgacatca aggaagacca ggttccggct
     1561 gctctggatg caatccgtct tttcaaaatg agaggcgcaa acgtaactat gccatgcaag
     1621 aacgaagttg caaaacacat ggatgagctt tcacctgcag caagaatcat cggtgcagtt
     1681 aacacaatcg ttaatgaaga cggcaaatta gtaggacata tcacagacgg tatcggattt
     1741 gtccgcaact taaaagaaca tggcgttgac gtaaaaggca aaaaaatggt agttctcggt
     1801 gcaggcggtg ctgcaacagc aatccaggta cagtgtgcat tagacggagc agaatccatt
     1861 tctatcttca atccgaaaga cccattcttt gcacgtgcag agtccacagc agagaaactg
     1921 agcaaagaaa caccggattg taaagtttct gtatttgatc tggaagatga ggcaaaactg
     1981 aaagaagagg ttgcaaacgc agacatcctc gtaaacgcaa cacttgcagg aatgaaacct
     2041 cacgaagagc ttactctgat caaagataaa tccatgttcc gccctgacct tgtagtagca
     2101 gacgttgttt acaatcctgc tgaaacaaga atggtaaaag aagccaaaga agcaggctgc
     2161 aagcttgcaa tcggcggaaa aggaatgttg ttatggcagg gagctgcagc ttacaaactc
     2221 tacacaggac tggaaatgcc aacagctgaa taccagaaat tccaggaaga aaacgaaaac
     2281 aagtaataat aacccaggag accaaaatga aacagaaaac aaacaaaatg ctcattttca
     2341 cctcccttgc agcatatttc acttatttca tccatggaat cggtgcttct atcctggggc
     2401 agtacaaacc ggagtttgca gctgcctggg gtgcgaagcc cctggccgat ggcacactgg
     2461 atgtaagtat ggtagtatct gtaattgcag cacttggact gggacgtctg atttctcttc
     2521 ctttctccgg ccctctgtct gacaaatacg gaagaaaact gagcggaatt atcggtgtgc
     2581 tctgttatgt agcatacttc tttggaatgg ctaattccac atccatggca atgggatatg
     2641 catttgcagt gatcggcgga attgcaaact ctttcctcga tacctgcgta agccccacct
     2701 gtatggaaat ctatgtaaac aacccgtcag tagccaacct gtttacaaaa ttttccatct
     2761 gcctgagcca gttcctgctt ccattcctga tcggaatcgt agcatctgca aatatgtcat
     2821 ataagacaat ctttattgtt gcaggtattg caatcctcat tgacggaatc ctgatcctga
     2881 tcctcccttt tccggcgaga gagaaggcag tacaggctaa agctgataag aagaaatccg
     2941 gacacaagat ttcccctgca gcgattgctg caattctgat cggattcacc agttcctcaa
     3001 cctttatgtt atggctgaac tgtaatcagg aacttgcccg ttcctatggt atggcagacc
     3061 cttcaaagat ccagtccctg tatgccctgg gaactgcaac tgccatcctt gcaacagcag
     3121 catttatcaa aaaaggtctg aaagagatta acgtcctgat cctctatccg ttaatctcca
     3181 ctatcatgct gctcctatgt tactttatcc aggccccgtt tatttgcctg atcggtggct
     3241 ttgtgatcgg atatgcaggt gcaggcggtg ttctccagct ggcagtttcc accacagcag
     3301 agttcttccc tgagaataag ggaacagcaa catcactggt aatgatcgca tccagcatcg
     3361 cgaactacac aatcttaagc cttgcagggt acattaccaa agttggcgga agcagtgctc
     3421 cgagaatgat ccttcttctg aacatggcag tgaccatcgt cggtatcctg ctcgccctct
     3481 ttgtaaagaa gaacagaaat cagtaaggca gtgtgccaac aagttgattt cctgaataat
     3541 ctcgcatcta aatttcttat tttcgcgttg ttgtcgggtg tcgtagctac cgctatgcct
     3601 cctttctacg ccttgaaata aaaaattatt aaaatccaat ccaactgaag atatgtttgg
     3661 acgttacaag tttcagattt tttccggtcg gattggattt tattaaaatc tggattgttt
     3721 aaaaattaac aaaaagatag aatatacaag ctgaaatata gaagtaatct aacaattcac
     3781 tgaaaaggag aaattgtatg gcacatacaa gaacacaaag aagagaaaat gaactgccct
     3841 acatcccctt tggaccattt cagataagac ttccattcat acactacaag atagaatctg
     3901 ttgagttcat tcagggtctg atcctgggcg taacagcact ggcagctgtt ccttatctgg
     3961 agcaatatct ggggcttcct tatgagctgg cgtggagctg tgtaattatt gagacatttc
     4021 tttatctgct ccacagtctg cttggcgatc cggtagtacc ggggtggatc acacccacac
     4081 tgcctctgac catcgtattt ctggaaggct tccctatggg agaggagagg atccaggcaa
     4141 tgatcgcact gcagatgctg gtaggtctgg tatttatctt tatgggtgtg accagactgg
     4201 cggataaatt tgttcatgca gttcccaatt ctgtcaaagg cggaatcctt cttgcagcac
     4261 ctgttacagt tatggcaggg cagctgggag agaatggaaa tatgcacaaa tatcctctgg
     4321 ctattgttgc aggtgtaggc ctcctgatcc tgatcagctt ctctgacaaa tatcaggaga
     4381 agagaaaaac aaataagttt cttgatcttg ttgcaagata tggaaatctc ttcccatatc
     4441 ttatcgcaat ggtagtagga cttctggttg gagaactgga tgctccggga ctggagattg
     4501 gtacttttat caagattcct cagtttaaag atatcattga tcaggtgagc atttttggcg
     4561 tagggattcc tcctgcatct atgtttatca aagcattgcc gctggcactg gtgtgctatg
     4621 ttattgcatt tggtgatttt gttactacag agactcttgt atcagaggca cgtcaggcga
     4681 gagatgatga gtatattgat ttcaattcca gccgttccaa tctggtcagt ggtctgagaa
     4741 atctgatcct gtccatcatt gcaccatttc ctccactttc cggtccgtta tgggttggaa
     4801 tgactgtatc cgtatccatg cgttacaaag aaggaaagaa agctatgaag tcccttctcg
     4861 gaggaatggc ttctttcaga ctggccacat tcttaagcgt gctgatcatt cctgtggtaa
     4921 gcttcttccg tcccatcttc ggagtaggct cttccattac tctgatgttc caggcatttg
     4981 tatgtgcgag aattggtatg gattactgca agagcgacag agacaagatg atcgcaggcg
     5041 taatggcagc agtcctcgca acccagggaa ctgcatgggc atctgcatgg gcactggcag
     5101 ttggcttcgg actgaatatc ttcctgtcca actggaatcc ctttgagaaa aaataatata
     5161 aacgaaaacc aagaagaaca gccgggattc ggggctgttc ttcttggttt tcatcaatta
     5221 ttattttaag gagtcataat tattaaattc aaattctgta acaatctgtt gacgaatata
     5281 agtgatatca gctataggca agaataacat ctgatatcac atcattcatc aacagatcac
     5341 agactgctgt gaatgatatc cagcacctgt tttaattcat gcacaccgac ctgtcccgga
     5401 gcagaagctt tggaagcagc accgaaggtg agagcggagc cgaatgtctc acctgtcagg
     5461 cggctgacaa cgcctgttcc tgccatggac atggtaatga tcgggcggtc tgcatatttc
     5521 tcagacattt ccagagtagc agagaggagt gtaagaacat cctgtttgca ggtcggcata
     5581 acagccattt tcggaatatc agcaccgaaa tcctgcatca tacgaagacg tctgataatc
     5641 tcctccttct caggagtctt aaagaaatca tggttggaag caattacctt cacacctgcc
     5701 tcgtgagcag cgtcaatgat cgtttttaca atatcatcgc ctgtaaatgc ttctacatcg
     5761 attaaatcta cataaccgct ctgagcagcc gcgatattta aagcagcgta atcacttaca
     5821 gaaatctctt tttccccgcc ctctttggaa gtacggaatg taagaagaac agggatatct
     5881 tttaaaactt cctgaagctc tttaacggtt tctaatactt tctcagtagc aaagacatca
     5941 tcaaaccagt ctacacgcca ctcaactaca tcaacaggaa gagtagtgat ctttttggct
     6001 tcttcgagaa tgtctgtttt tgtttttcct acgatgggaa cgcagatctt aggtctgccc
     6061 tcgccgatca cagtgttttt tacctgaact gtgttcatct gtttatcctc atattttctg
     6121 ttgtattata gtagttccgg attattatgg aactgttata agaataaccg taacataacc
     6181 gcatgatcaa cagctttttg aagcaaactg caggatatgt acattctgcg cggagtaata
     6241 tatcagtaca tctcctgcag tacgccgaaa agcggtatat atcaaatatt atgtgcagaa
     6301 agatcagtga aatgatctgt tctgcatcac aatatgagat atccatactg aagataccat
     6361 caggtatcag tcatcatagg agatgtgaag aatctctttc atatgttcga taggcattgg
     6421 ttcgcctgtc cataactcaa atgcagcgga accctggaat aacatcattc ccagaccgtt
     6481 cattgtcttg catcctacct ctttggccat ggaacgcatc tttgtttcca gcggagagta
     6541 aggaacatca ataacgatca gctcaggacg gaagtaagac ttgtccggaa caacggactg
     6601 gccttccaga ggtttcattc ccacacctgt agcatttacg aaaatgtagc tgtcatccat
     6661 ctcagttttc agtttatcaa gatctgccag atcataaaga actgcatggc aggaggtctt
     6721 tgtgttgatc ttctctactg tggatactgc acgatcccag aattcatcct tgcggttaaa
     6781 gattgtgatc tcggcaacgc cgtccaaagc agcctggatc tcgatagcag tggcagcacc
     6841 gcctgcaccg acgatagtca ttttctttcc gatcacatca atatcattat ctttcagggc
     6901 agacataaac ccaataccgt cagtgatatg acctgtaaga tgaccgttgt catttacgat
     6961 cgtgttaact gcaccgcata attctgctgc aggagaaagc tcatccaggt attttccaac
     7021 cagagttttg tttggcatgg aaacattgga tcctctcatt ttcagagtgc ggattgcttt
     7081 tactgcatcc tcaatctcat ctgcgccaac ctcgaaagca aggtaagcgt agtcataccc
     7141 gagttttgca aaagcctcat tctgcattgc aggagagctg gagtgacgga tcgggtaagc
     7201 catcaggccg attaattcag tatgtccggt aattctttca gccattataa tatccccttt
     7261 cgtattttgt tgtaaaggtt tttattaaag gtatcccatc tgagtcagtg tattaaggat
     7321 atttcttcct tccagagttc cgtcgatgat ccttcttgca cgtttgctgt ctccgatgtt
     7381 cagaatctca acatcatcag aaacaaaagc atcggaaagc tctgtgaaag gctgtccctg
     7441 agctctcata ccaagacata cgaatccgta gtcaaatgga agctcacgtt caccttctac
     7501 atcttttaca aggaaagagc tgtcttttac ttcctgaaga gctgtctttg taagctgagc
     7561 cacatgatgt ttcttcatct ggtccttcat gtcattcttt gtaacaggat ccaggtcacg
     7621 tccaatctga tccatcatct ccacaataga aatctcggca tttcttgctg caaagaattc
     7681 cacaacatca agaccaacag cgccgccgcc cacaacaaca accttcttgc ctgtcatgtc
     7741 ttccggataa tcattgatgt gattaatcat tcccaggata gaagcaatct tgctgccttc
     7801 tttgtcaatg cggtcgtgaa gtcccttgat cggaggaagc agtggtgcgg aacctgtgga
     7861 gcttacgatc aggttcggat ggaacttgcg gatattttcc ggtgttccct ctgtgtttgt
     7921 aaagatataa agattctcaa gttgcgctgc tctgtggatc agatagttcg ggaaatcagc
     7981 cagacgcttc tttgcaggaa tcttagagat cacagaagca agaccgccaa gagtctcacc
     8041 tttttccaga aggaaggtat tacagcctac ttctgcggct gtacaggcag cttccagtcc
     8101 ggccgtaccg cctccgatta ctacaacgtt acagttcttg ttcactttct gattcttata
     8161 aacatcacct tccagaacag ctgggtttac agtacagcgg atcggacggt taaagccgat
     8221 tctgtttcct gcacatccga tgttacagga gatacatttg cgaaggtcac attctctgcc
     8281 tgtagctact ttgtttaccc atgcaggttc tgcgataaga ccacgtccca taccgatcag
     8341 gtctgcatcg ccgtcagcga ggatctgctc ggcaaccttc gggttacgga tatttcccat
     8401 ggagatacat ggtttgccga atttctctct gacagcttta ggcatatagg aacgccatcc
     8461 gtctttcatg tagttggcat cgatctgata ctggatagaa ccgtttaaac cgcaggaaac
     8521 atcgaagata tcaacttcat cctgaatata ttccagatat tcaagagtat cctcgagagt
     8581 attgccgcct tccatcagct catctgcgct gagacggagc atgatcggga agaaaggtcc
     8641 aacctgtttt cttacttcct caatgaccat acggcagaaa cgtgttctgt tttccacaga
     8701 tccgccgaac tcatctgtac gtttgtttgt aagaggagag aggaactggc tgatcagata
     8761 ggaatgtccc gcatggatct ctactgcgtc aaaacctgca gcctgtgccc tctttgcagc
     8821 ctcgccgtat ttctttacaa tgtgatggat ttcttccact gataacgtac gcgggatttc
     8881 tccgccttct ttggacggaa catcagatgc ggaaaccggc tgcatatttg tacgtgcgga
     8941 aacagcggaa gcacctgcgt ggttgatctg gattgcaata caggtaccat atttgtggat
     9001 ctcttcacag aatttgtaca gacgcggcag atagttgtcg tggtcaatac gaagctgagt
     9061 agttccgttg gaaccctgcg gagaatctac gcttgcattc tctacgatga tcagacctgt
     9121 gccgcctttg gcacgctctt tataataatt aatgtgaaga aaactcattt cgccgttctg
     9181 ttccccgtaa ttggttccca taggcatcat aacgatacgg tttttgatag tcatattttt
     9241 tactgtgagt ggtgtgaaaa tatgctggta attgcttttc attacgtctt tcatcctgaa
     9301 attttctgtt ggatctatag caatactcta aaataatgca ttttaatcaa gtccatcaga
     9361 gtgtgaaatc ctgcgtcaga tatctttgcc gtgcgtcagc acgcctgcag atagagtact
     9421 gggctttcgc actctgctgc actgtcttaa atgcattatt tacgaggagt tctatataat
     9481 tgttcagtgc tttagctgtg gcctgaattt ctttgatgtg ttaattatat aacgggataa
     9541 tccataaatc taattgataa ttcgtgctat ataataaaaa acatctatgg ttttgctgag
     9601 acttttatac ctgtgcagtc ggattcgcag acaagtgaga ggtatagtta cctcaaacac
     9661 gctctggtgt gccgacaagt tgattcttga aacaatcttg caggatagaa ataagaaatt
     9721 cagacgcagg attgttcgag aaatcaactt gtcgacacac tggtttgcgg gagagggtga
     9781 aatacaggac aatacaaaat aaccgtaata ccctctatta aataggaaga aatgctcaaa
     9841 aaaacaaaat ttggagaaac ctgacaaatt tttctgctat atttttaacg aaaatgacaa
     9901 ataaatgttg aaattttctg ccggaaaagg taaaattaaa atcggctaaa tttttgggtt
     9961 aacttttaaa tattctcata aagatggagg gcaaacaaga atgagtaatg caacacaaag
    10021 cttagcaggc acaagaatta cttctttgct tgacgcaaac agttttgtcg aaatcggaca
    10081 gggtgtaaca gccagatcca cagatttcaa catgactgca aacaaggcac catctgacgg
    10141 tgttatcacc ggatatggtg tgatcgatga caaactggtt tatgtataca gccaggatgc
    10201 atctgtatta aacggtactg ttggtgaaat gcatgcaaag aagatcacaa gactttatga
    10261 tcttgccatg aaaacaggcg ctccggttat cggacttgtt gactgtgcag gtatccgtct
    10321 tcaggaagca acagacgcac tggaagcttt cggacagatc tatctgaaac agacactggc
    10381 atccggtgtg atcccgcaga tcacagcaat cttcggaaca tgcggcggtg gtatggcagt
    10441 tatcccgtcc ctgacagatt tcacattcat ggaatccaaa aaaggaaaaa tgttcgtcaa
    10501 cacaccaaac gcactggaag gaaacaacac agacaaatgc gacacagcag cagctgattt
    10561 ccagagcaaa gagacaggtg tgatcgatgg cgttggtaca gaggatgaga ttcttggcca
    10621 gatccgttcc ttagtatcac ttcttccttc taataatgaa gacacagaca attacacaga
    10681 gtgtacagat gatcttaacc gcgtatgcgc agatcttgca aactgtgcag gtgacacagc
    10741 aatcgcactt tcccagatcg ctgacaacgg tgaattcttc gagacaaaag cagactatgc
    10801 aaaagacatg gttacaggct ttatccgttt aaacggcgct acagtaggtg ctgttgcaaa
    10861 cagaagcgaa gtatatgacg cagaaggtaa gaaaacagaa acatttgacg gaagcatctc
    10921 tgcaagaggc gcaagaaaag cagcagattt cgtgaaattc tgcgacgctt ttgatattcc
    10981 ggtacttaca cttacaaacg caacaggctt catggcaacc ttatgcagcg agaagatgat
    11041 ggcgaaatcc gtaggtgaac tggtagctgc attcgcagat gcaactgttc cgaaggtaaa
    11101 tgtgatcatc ggcaaagctt acggtacagc ttacgtggca atgaacagca aatctatcgg
    11161 tgcagacctt gtatatgcat gggataacgc agagatcggt atgatggatg cttccctggc
    11221 agccaagatc atgtatgcag atgcagatgc tgctgaactg aatgagaaag ctgctcagta
    11281 cagagagctt cagaatggtg ttgcttccgc agcagcaaga ggctatgttg acactgtgat
    11341 cagcccggct gacacaagaa aatatgtaat cggtgcattt gagatgctgt tcacaaagag
    11401 agaagatcgt ccgtctaaga aacatggaac ggtctaagcg gggtgacgca tatgaaaatg
    11461 atcaaaaaaa taacttctgt attcatgaca tttctcgtaa tggctgcgct ggtgatcggc
    11521 agcacctctg tggtatttgc cgcagataag gttgatgata ctgttaagtc cacactggta
    11581 actacagcag aaggactgac agatgccatt gtccagctta aagatgaaga aatcgagaat
    11641 tacatgagtt caggagatga ctttacaaca agtgccatgc agtcctggca gacatccaag
    11701 gatgaacttg gcgcaaagaa ggacagcaat ggtgaaacta ctgtaacttt caaagatgat
    11761 cagtacacag ttactgttcc tcttaaattt gagaaagcag aagcaaactt tgtatatgtc
    11821 tttgactcac agggaacacc gacttccatg tctgtagatg tacagtatgg tatgggcaag
    11881 actcttcaga gagcaggcct taatactttg atgggtattg gaactgtatt cgtaatgctg
    11941 attttattaa gccttctgat ttctctgttc agatttattc cgaatccgga agcaaagaaa
    12001 gcagcagaag caaaagcagc caaagctgca aaagaggcag aggcagcagc catcgcacag
    12061 acagcacctg cacaggcaga agagaacctt gcagatgacg gagagctggt agctgttatc
    12121 gcagcagcca tcgcagcagc agaaggaact acaacagatg gcttcgtagt tcgttccatc
    12181 cgtaaagtaa aaagaaatag aagataattg tcatttattt aggaggattt taaaatgaaa
    12241 agctatacaa ttacagtaaa tggtacagca tatgaagtaa ctgttgaaga aacaggaagc
    12301 gtatccgctc ctgcagcagc tccaaaagca gcacctaagg ctgcacctgc agcagctccg
    12361 aaagcagcag ctcctgcagc aggcgccggc gcagtgaaag taactgcttc cgtacctggt
    12421 aaagttgtca aagtagcagc aagcgttgga caggcagtaa aagccggaga cagcgtaatt
    12481 attcttgaat ccatgaaaat ggaaatccct gtagtagctc ctcaggacgg tactatcgca
    12541 agcattgatg ttgcagaagg tgcctctgta gaaaacggag atactttagc aacaatgaac
    12601 taagacggga ggtagtcaaa tgtcttatgt aacagaaaca ttgtccaacc tgattcacca
    12661 gacagcattc ttcaatctga catggggcaa ttacctgatg atcgcagtag cctgcgtatt
    12721 cctttatctt gctatcaaga agggattcga gccgcttctg cttgttccta tcgcattcgg
    12781 tatgctgctt gtaaatatct atccggacat tatggcaaac ccggaagata tgtccaatgg
    12841 tgtaggtgga cttcttcatt atttctacat ccttgatgag tggagtatct taccatccct
    12901 gatcttcatg ggtgtaggtg ccatgacaga cttcggtccg ctgatcgcaa acccgatcag
    12961 cttcctgatg ggtgctgcag cacagcttgg tatctatgca gcttacttcc ttgcaatctt
    13021 ccttggattc aacggaaaag cagcggcagc tatctccatc attggtggtg ctgacggccc
    13081 gacttccatt ttccttgcag gtaaacttgg acagtctgca ctgatgggac cgattgcagt
    13141 ggcagcatat tcctatatgt cactggttcc gatcatccag ccgcctatca tgaaactctg
    13201 cacaacagag aaagaacgta agatcaaaat ggatcagctt cgcccggttt ccaaactgga
    13261 gaagatcctg ttcccgatcg ttatcacaat cgttgtctgc ctgatcctgc ctacaacagc
    13321 tccgctggtt ggtatgctca tgcttggtaa cctgttcaga gagtgcggtg ttgtaaaaca
    13381 gctgacagaa acagcttcca atgccctgat gtatatcgta gttatccttc tgggtacatc
    13441 cgtaggtgct tccacaagtg cagaagcatt cttaaacgca gatactctga agatcgtagt
    13501 tttaggtctt gttgcattcg caatcggtac attcggcgga tgtatgcttg gtaaactgct
    13561 ctgcaaactg actcacggac gtatcaaccc gctgatcggt tccgcaggtg tatccgcagt
    13621 acctatggca gcccgtgtat cccagaaagt gggtgcagag gcagatccta caaacttcct
    13681 tctgatgcac gcaatgggcc cgaacgttgc cggtgttatc ggtacagccg tagcagccgg
    13741 aacattcatg gctattttcg gtgtataatt gaatttataa aggagattta ataatggcag
    13801 aattagagaa aaaacctgtt aaaattgtgg aaaccattct ccgtgatgct catcagtccc
    13861 agattgcaac acgtatgacc acagaacaga tgcttccgat cgtagataaa cttgacaaag
    13921 tcggctatca cgcagtagag tgctggggtg gtgcaacatt cgatgcatcc cttcgtttcc
    13981 ttcacgaaga tccatgggaa agacttcgta aattacgtga cggcttcaaa aacacaaaac
    14041 ttcagatgct tttccgtgga cagaacatcc ttggataccg tccatatgca gatgacgttg
    14101 tagaatactt cgtacagaaa tctgctgcaa acggaataga catcatccgt atttttgact
    14161 gcctcaatga ccttcgtaac ctgcagacag cagtaagcgc tgcaaacaaa gagaaggctc
    14221 atgcacaggt agctctttcc tacacattag gagatgctta cacactggaa tactggacag
    14281 acattgcaaa acgtatcgaa gatatgggcg ctgattccat ctgtatcaaa gatatggcag
    14341 gtcttctcct tccaaacaaa gctacagagc ttgttacagc attaaaagaa acagttaaga
    14401 tcccgatcga ccttcataca cattacacct caggtgtagc ttccatgact tacttaaaag
    14461 cagtagaagc aggtgtggat atcatcgata cagcaatgtc tccatttgca ctgggaacat
    14521 cccagcctgc aacagaggtt atggttgaga cattcaagga tacaccatac gacacaggat
    14581 ttgatcagaa gcttctctcc gagatcgctg actacttccg tccgatccgt gacgaagctc
    14641 ttgacagcgg actgctcaat ccgaagaacc ttggtgttaa catcaaaact ttactgtacc
    14701 aggtaccggg cggtatgctc tccaacctga cttctcagtt aaaagaacag cacgcagaag
    14761 acaaattcta cgatgttctc gaggaagttc cgcgtgtacg taaagacctt ggtgaaccgc
    14821 cacttgttac tccgtcttcc cagatcgttg gtacacaggc tgtattcaac gtactcatgg
    14881 gcgagagata caaaatggtt acaaaagaaa caaaagatat cctgttagga aaatacggcg
    14941 caactgtaaa accgtttaat ccggaagtac agaagaagtg catcggcgat gagaaaccaa
    15001 tcacatgccg tcctgcagac cttcttgaca acgagcttga gaaacttgag agcgaaatgg
    15061 ctcagtacaa ggaacaggat gaagacgtat taacatacgc actgttccca caggtagcta
    15121 tggacttctt caaataccgt caggctcaga aaacaaaagt tgacgagaaa gcagctgaca
    15181 aaaagaacgg agcatatcct gtataattga tcagtaatta aatatgtcca aacgaaaaaa
    15241 ggagcttgcg caagcaggct cctttgcgtt attatgaaag aatatgatac ccgggaatat
    15301 aatgtgccaa tgggtatatg atgccagagg tacatatcta tattgatcgt agtgaagcgg
    15361 agacgtggaa ccatgatgaa atagacaatc tgcagggtaa aataaataca ggagaatatt
    15421 ccatgagcaa agttataata atcggcggcg gagccgccgg aatgatggca ggggtttttg
    15481 cagcccgtaa ccatcatgaa gttcatatat tagagaagaa cgagaaactg ggaaagaaag
    15541 tcttcatcac aggaaaaggc agatgcaatg tgacaaatgc ctgcgacaca gaagaactct
    15601 ttcctgcaat gatgagcaat cccaagttcc tctacagcag tttctattca tttacccctc
    15661 aggatgtaat ggagttcttt gagaaagcag gtgtccctct gaaggtagag cgtggaaacc
    15721 gcgtatttcc acagtctgac cattcctcag acatcatccg cgcattggaa cgtgaactga
    15781 agaaagcagg agcaaagatt catcttcaca ctgctgtacg ggaaattgta aagaaacctg
    15841 taacagattc ggcaaatacc ctggaatcag aagccgcatt aacagaatca ggatctgatg
    15901 caggaaaagg cagaaaagga aaaaaatcac ctgacatacc gcaggagaag atcgcaggag
    15961 tcatccttac agacggaacc ttcatggaag gcgatgcagt catcgtggca accggcggat
    16021 tctcttatca gagtacaggc tccacaggtg acggataccg cttcgcaaga gaactgggac
    16081 tgaaagtcac ggacattgct ccctcccttg tgccattaaa gacaaaagaa gactatgtcc
    16141 ctaagcttca gggactttcc cttaagaata caggacttac cataaagaat ggaaagaaag
    16201 tactctatga ggatttcgga gagatgatgt tcacccattt cggagtcaca ggccccatga
    16261 tcctttcagc cagtgcccac atcggtgcaa aactggcaaa agcaccaaac ggcgaactgt
    16321 ccgcatatct ggatctgaag cctgcactca caaaggagca gctggatgcc agaattctgc
    16381 gtgaattcga ggcaggacct aacaaacagt tcaagaacgt gatcggagta cttttcccat
    16441 catctctgac acctgtaatg atagagctgg ggggtattcc tgcagagaaa aagatccacg
    16501 atatctccag ggaagaacgt cagcacttca tagatcttat caaagccttc ccattcacga
    16561 tcacaggaat gggcgaattc aaggaagcca ttatcaccag aggcggcgtc tctgtcaagg
    16621 agatcaaccc cggaacaatg gaatcaaaga aaatttcagg cctctacttc gcaggtgaag
    16681 tgctggatct ggatgcagtg acaggcggat acaatctgca gatagcatgg tcaaccgcat
    16741 atctggcagc acaggctata cagtaagctg tttattatag aaacaaacaa atgatgagca
    16801 ccttgtaagt ggattatatc tatgatatga ttcgactata cattatctaa cgattaataa
    16861 acatcaatca ataataaaac agagaaaatc tgtttgaata atagaaacag gaggaaccgc
    16921 gaaaatggga tgtaacatag ccatcgacgg acctgcagga gcaggtaaga gcaccatcgc
    16981 aaaaaaagta gcaaaagaat tatcatttat ttacgtagac acaggagcta tgtacagagc
    17041 aatggcttta tatcttctga accatggcgt aaacggagaa aatcaggaag agatcgaagc
    17101 cgtatgttcc ggcgctgaca tctccatcga atacaaaaac ggagaacaga ttgttatcct
    17161 caacggagag aacgtaaatg ctatgatccg cactgaacag gtaggaaaca tggcatccaa
    17221 aagctccgca aacccgaaag tcagagccca ccttctgaaa cttcagagaa ctctggcaga
    17281 gaaaaacgac gtagtcatgg atggcagaga tatcggcaca actatccttc caaacgcaga
    17341 agtaaaaatc tacctcacag caagcgcaga caccagagca aaaagaagag cactggaata
    17401 tgaacagaag ggagaatcct tcgacctgga ccagatccga aaagacatca tcgagcgcga
    17461 cgaacgcgac atgaaccgcg aaatctcccc tctgaaacag gcagacgacg cagtgctcgt
    17521 agattcctcg gaaatgggaa ttgatcaggt tgtagatgct attcttgatg tgtataataa
    17581 gaagatacag aaataacggt caggcggaca gattatctgt ttcagactac gctatctgcc
    17641 cgtcaactac ctatcaccta aagtggtgct gcatcatagg gtggttgaca gcacccttta
    17701 cagacaagat atactcatct gtaactgtaa acttcccatg ctatacagca aacattcttt
    17761 tacgggtaag gaaaggattt atttatgaaa gttaaagtag cagagacagc aggcttctgc
    17821 ttcggcgtca aacgggcagt agacaaagtc tacgaactga tcggcacaga acagaaacca
    17881 atctacactc tgggtccgat catccacaac gaaggtgtag tagcggatct ggaagcccgt
    17941 ggcgtccacg ttatcacaga agcagacctg gattccccgg atgacaccct gcagaacgga
    18001 acagtagtca tccgctctca cggtgtaggc aaagccatct acgataagct gaaagaaaaa
    18061 aacatctctt atgtagatgt gacctgcccc ttcgttctga aaatccacag gatcgtggaa
    18121 aaagaaagcc ttgcaggaaa ccacatcatc atcatcggcg acaaagacca ccccgaagta
    18181 cagggcatct gcggctggtg tcagggaccg tacacggtga tcagaaacaa agaagaagcc
    18241 gaagtatttg tacccccaaa aggcaaaaaa ataagtattg tgtcccagac gacatttaat
    18301 tacaacaaat ttaaagattt agttgaaatt ctttgcaaaa agaggtatga taataatgtt
    18361 ttaaatattc tcaatatttt aaacactatt tgtaatgcta ccgaagaacg gcagagagaa
    18421 gcaaaaaaca tagccggaga ggtagacact atgctggtcg taggcggccg gcacagttcc
    18481 aatactcaaa agctgtttga aatatgtaaa aaggaatgtg gaaatactta ctatatacaa
    18541 acacctgtag acttggattc tgaaatgttc caatgcagta gttatgtagg tattacagca
    18601 ggggcttcca ccccaaacaa aattattgag gaggttcaag aacatgtcag aattaagttt
    18661 tgaacaaatg ctggaagatt ccgtaaagac tatcagaaat ggagagattg tacagggtac
    18721 tgtcatcgat gtaaaagaag atgagattat tctgaatatc ggttataaag cagacggtat
    18781 tatcacaaag aacgaatact ctaacgatgc aagccttgta ctcacagatg ctgtccacgt
    18841 tggagacaca atggaagcaa aagttctcaa agtcaatgac ggagaaggtc aggtaactct
    18901 tacttacaag agactggcag cagagaaagg caacaaacgt cttgaagaag catttgagaa
    18961 tcaggaagta ttaaaagctc ctgtaactca ggtacttgac ggtggacttt gtgtaaacgt
    19021 agacgaagca agagtattca ttcctgcaag cctcgtttcc gacacatatg agaaagacct
    19081 ttccaaatat gcagatcagg agattgaatt cgttatcaca gaattcaacc cgagaagacg
    19141 ccgcatcatc ggtaaccgta agcagcttct tcttgctgag aaagcagaga aacagaaaga
    19201 attaatggag aagatccatg ttggcgacac agttgaagga acagttaaga acgttacaga
    19261 tttcggtgca ttcatcgatc ttggcggagc agacggactt cttcacatct ccgaaatgtc
    19321 ctggggcaga gtagagaacc cgaagaaagt attcactgtt ggcgataaag ttaaagttct
    19381 tatcaaagag atcaacggag agaagatcgc actttccctt aaattcccgg aagcaaatcc
    19441 atggctcaca gcagctgagg acttcgctgt aggaaacgta gttaaaggta aagttgcacg
    19501 tatgacagac ttcggtgcat tcgtagagct tgcacctggt gtagatgcac ttcttcatgt
    19561 atcccagatt tccagagagc acgttgccaa accagcagac gtactgtcaa tcggacagga
    19621 gatcgaagct aaggttgttg acttcaacgg cgaagataag aagatcagcc tgagcatgaa
    19681 agctcttgag gcaccggctg aggaagctac agaagaataa ttaagagaat actcataaat
    19741 attcagcaac cggctttgta tgaggatgat catacagagc cggttgatta tttttttaga
    19801 ttacgaatgt ggtcagcagt tacaggagca tcagaaatgc tgcagacagt caggaaggaa
    19861 tgataggatg tccataaaag gaatttatga tatacactgt catattgtac ccggtgtaga
    19921 cgatggagcc acagatatag gagaaaccgt aaaattactc cggatggaat atgaacaggg
    19981 tgtgcggacg gttattgcaa ctccccattt ccgctttcgg atgtttgaaa cacctgcgga
    20041 gaaagtcaga gagcagttca gactggtgga gaaagcggca tcagagatca gcccggatct
    20101 ccatgtgtat ctgggatgtg agtttcacgc caatatggag atgcttccca tgctcagaga
    20161 acagaaagta atgacaatgg ccggttcgcg gtatgttctt acagaatttt cccataactc
    20221 ggaagaaagc tatatacggg aacgtctcgg tgcattgctc tccggaggat ataagcctat
    20281 catggcacat atagaacgtt acgaagccac acgtaacagt ctggattttg tggaagaact
    20341 ggcagatatg ggcgtctata tgcagatcaa tgcagacagc atcacaggaa aagatggatt
    20401 ttttactaaa cggtactgta ataaaatcat gaaagacgga ctccttcatt tcgtcggatc
    20461 agactgtcac aacagtacaa agaggagcag caggattgga gaggcatatc gtatggtttc
    20521 agcgaaattc gggcaggact atgcagatga actgtttatt cataatcctg cagaaattct
    20581 gaaacagaaa caaaaacatg aggctacaga ttgacttttt ttattggctg atatacaata
    20641 aaatcggttt atgtcaattt tgctgtttac tttcagaaat acataagaca gaatattacc
    20701 tgtgaacagt aatgtacaaa actataaaga aaaaagggaa aaggaaatta tcagatgtta
    20761 gacaatttga acagtaactt tgagagcagc aaagcacaga gacccgatgc aaatgatgat
    20821 gaagtcgaaa tcgacttact ggaaatattt tatgcgctca agaaaaaaat ccttctggta
    20881 ctgatggttg ctcttgccgg aggctgtatt gcagcagcat atacgcagtt tttaatgaca
    20941 ccgatctaca gctccacatc cagtatcctt gtactttcga aagaaaccac actgacatca
    21001 ctggcggatc tgcagttagg tgccagcctg accagtgatt atacagttct gatcacaagt
    21061 acccctgtga tggaacaggt gatttcagat ttggatctgg atatgactgc agaacagctg
    21121 aaaggaagcg taagtatcaa taatcctaca gatacccgta tccttgagat tactgtcaat
    21181 aatacagatt ctaaaatggc aaagaagatc gtagatgaga ttgcgaatgt ttcttcatcc
    21241 tatattggcg ataaaatgga agttattccg ccaaagatta ttgaagttgg taagattgct
    21301 actgtaagaa cttctccaag cgtaaagaag aatgcagcac tcggcttctt actcggtttc
    21361 cttgcatgtg cggcaatcgt ggttgtatac gctgtaatgg atgatactat taagacagag
    21421 gaagatattg agaaatacct gggagtttct gttcttgcca aggttcctga cagaaaagat
    21481 tttataaatt cgaagaacag gaaatcaaag aacaagaata agaagcacca ttaaactgat
    21541 ggaggaatct gagcaatgaa gaaactcaat ttaacagata aaagaaatcc ggattatttt
    21601 tacagtgagg cgatcaaaac tctgcgtacc aatattcagc tgtcgggtca gagcataaag
    21661 acaattctgg ttacaagctg ttatccaaac gaaggtaaga gtgatatagt actcagtctt
    21721 gcccaggagc ttgggagtat tggcaagaag gttctccttc tggatgcgga tatcaggaag
    21781 actgcatatg ccggacgact gggtgtggaa gaggaagtga aaggtctctc acagcttctg
    21841 agcggtcagg tgggattaca ggaggttatt tattctacaa actttccgaa tatggatatc
    21901 atattcggag gcccaagtgc accgaacccg tcaggacttc tcagtgagaa tatctttaag
    21961 gtattcttaa aggaaatcag agaatattat aattatatcc tgatcgatac accgcctatc
    22021 ggaacagtaa ttgatgcggc agtgatcgga agatgctgcg atggtgcagt ctttctgatt
    22081 gaaccgggaa atgtcaggta ccgggacgca cagaaagcat ttaaacagct ggaaagaagc
    22141 ggatgccgta ttcttggagc tgttatgaac aagatagata ccagtgatga caaatattat
    22201 tcttcctatt ataagcatta tggagagtat tatcgcagaa gcgacgaaga agcccagatt
    22261 aaataatacg ggcagttatc tggcagtaag acagaaacca tgatcaatga taaaggagaa
    22321 tttggaaaag tgagcaaaat aaggaataaa aaaataaaaa agacgaatat cttactgggc
    22381 tttatctgca ttctgctggc agttctcctg ggctttattc ttgtgaccag ttataaatcg
    22441 gaacagaagg aatccagaca cctgtcagaa attgcggacg accagcagag tgggattgaa
    22501 gattacgaag cagtaaaaga acgtgcaaaa gagctggagg aggtatcttc cgaagaagca
    22561 gaagatacag aagacattaa atcaaagaac acagaagaca caaaagacac agaaaaaacg
    22621 gatacagctg acacagaaga tgcagataag acagaagata caaaagataa gacgacagct
    22681 gcttcaggta ttgtgtgctg gggagatgat ctgatcaatg gggaagaatc caatacatat
    22741 tcctatatga cagtacttca gaagcttctg accgataatg gctataatat gacagtagtc
    22801 aataaaacgc ttcagggagg cggcactctc tccatgatga agatggctgg tgtaagtgat
    22861 gaaactattc agagctatat taccagacat cagcaggctg caaacggtgc ccagttgaat
    22921 gtaacagaga ccggaatacg tgatctgaca gaagaacaga ctacaagaaa tgatatggat
    22981 tgtattccag ttattttcat gggatattat ggcggctgga atcatgatcc tgcagaactg
    23041 gcagaccagc aggaacagat tttaaataca tttcagaata aagatcagtt tattgtagta
    23101 ggaacacgcc ctatggacgg aagcgtaacc tctgaagcac ttgatcaggt gctcagccag
    23161 aaatggggag aacactatat cagtcttgca gatgtgactg cacagccgtc ttctacctat
    23221 gaggctcagc aggcaatggc agaggcaata ttacagaaac tgcaggagct taattatatc
    23281 agcaaaaact gatgagataa ctgaaataca gagattgaag gaatgaaaat gaaaaaaacc
    23341 acaagaaaag ccatcagaca gcgtaagatt tgtatgcttt tgattattat cctgattata
    23401 gttctttcca ttcttggcgg cggttattat ctgttaagcc agaaaaatgc tgcatcgtca
    23461 aaagccggtg gtcagaacag tgacagccgg aatcagacgg atttgaacca aaacagtgat
    23521 accgtggaat ataaaggtga gatatacaaa tataacaatc atctcagcaa ttatttattc
    23581 ctgggaattg acacaaggga agctgtagat acttatcagt cacaggcaga tgccgggcag
    23641 gcagatgcga ttttcctggt gtccatggat cgtgcaacag agaagataaa ggttctgttt
    23701 attccacgag attccatgac caggatagaa gtatttaatc catatggtca gagccttgga
    23761 gagacaacag atcatctgaa tatacagtat gctttcgggg acggaaaaga gaaaagctgt
    23821 gaactgatga aaacagcagt ttccgatatg ctggacggac ttccgatcca ggggtattgt
    23881 tccatgaaca tggatggcat ttcagtgatt acagatttcg taggtggaat acagctcaca
    23941 atccctgatg acagtctcgc agatgtgaat tcggaatata aaaaaggtgc tgttgtggat
    24001 atcacagggg aaactgcaga acagtttgta agatatcgtg acattgacaa aacccagagt
    24061 gctctggtcc gtcaggagag acagaaaacc tttcttcagg cactggtgca gaaggctcag
    24121 gaaaaagcag gagaggacgc cggatttgtg acaggtcttt atgacagtgt taagagctat
    24181 acagttacaa atatgggaaa tgatatattt gccaaattgc tggctgcatc acagaatgga
    24241 atcactgata cagagacagt accgggtgag ggaacacatg gggagaactt tgatgagtat
    24301 catatcgatg aagatgcatt gtcggatttg attatttcca tgttttatga gaaaatttga
    24361 ttgtattagt catagtatga tgaatacaga atacactgta ctgtgataaa taattatcac
    24421 tgttattatt cagagatagt ccgtgcagac attctgtacg gttatctata taaaaattaa
    24481 tccaaaagga gaggtgcatt atgaaaatcg cgaagaaatt tatgacactt gctttagtag
    24541 ctgcccttgg agtaggatgt gctactgtag gtgtcggtgc agcgccaagc aacacgagtg
    24601 atttggccgc ggtagcgcca agtaagacaa gcgaaattac tgtggattct aaacagtctt
    24661 caatttatga agttgttaag gaacttgaga aaacacaggg ctttgctgat ctgcaggcaa
    24721 aatataaaga tctggcagat gcttttaaaa aaatcaatga tggtacaatg aagatggaag
    24781 atttcataaa agtattgaaa tccctttctg tagatgaagc agacaaggca gaccttgaag
    24841 atgccattgc taaactcgaa ggaaaaatga ttgttacatt tgtctatgaa ttcaacgtac
    24901 tgaagccgga agaagcaaag cctaatgatg acggaacata tgaagtaaag cttaatgttc
    24961 cgagtcttac agacactatg gaaggtattc agctttgggt ctacagcaaa gacggcacaa
    25021 agaagtttgt agtcattgat ccggttaata ttgacaaaga gggcaaaact cttactgtta
    25081 ccttaaacga tggagatttc ttcatggtaa tcgcagacgc aaaataatca ataattcgga
    25141 atcagaacgc agtcgccaga gatggcggct gtttttttgt agaaatatgt tgcatttttt
    25201 tattga
//
