LOCUS       c00119_gnlPro..        14406 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GAGFMGDE_119.
ACCESSION   c00119_gnlPro..
VERSION     c00119_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 00:36:58
            Original ID  :: gnl|Prokka|GAGFMGDE_119
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14406
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14406
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4918:13334]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4919..13334
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14406
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14406
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             328..816
                     /locus_tag="ctg119_1"
                     /transl_table=11
                     /translation="MPKNKFQEVIFTIIMVFVMVYAMICYNIVLNTGTMTNETFLLAFH
                     ELTFMGPIAFILDFFIIGGLAKKIAFGVVDMRRDNPFHLVLAISAVSVAFMCPCMSFAA
                     TVLIKHAPASQIIPTWLQTTAMNFPMAFFWQIFYAGPFVRFIFGKLFPEKEKAAASAE"
     CDS             1018..2016
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SBP_bac_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1044:Bacterial extracellular solute-binding protein
                     (Score: 57.1; E-value: 9.5e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg119_2"
                     /sec_met_domain="SBP_bac_1 (E-value: 2.3e-18, bitscore:
                     57.1, seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRKLFAFGLAVVLALMPVQAFGKTVSITNVSYDPTREMFEQYNK
                     IFEDHWKEKTGDDVEVIQSHGGSGKQALEVANGLDADVVTLALEYDIESIENAGLIKAG
                     WKDKFDNDSSPYTSTIVFLVKKGNPRDIKDWDDLTKKGVGVVTPNPKTSGGARWNYMAA
                     WAYADKKYGGDEAQMKEFIKKLYRNVVVLDSGARGATTSFVENGQGDVLVAWENEAYLS
                     MRDYPDEYEIVTPSVSILAQPSVAVVDEVVDYRDTRDVATEYLNYLYSDEAQEIAAENY
                     FRPTNEKILKKHSNTFDLNINLANISDYGGWDKVQEKHFTDGGIFDQIYER"
     CDS             2087..2923
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 83.5; E-value: 5.1e-26)"
                     /gene_kind="transport"
                     /locus_tag="ctg119_3"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.2e-26, bitscore:
                     83.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRNKPVIPGFGLSMGITISILSLVVLIPLASLVVYTAKLSFKD
                     FIETITRARVLASFYTSFVCAFAAAVINGIMGTILAWVLVKYDFPGKRLMDGMIELPFA
                     LPTAVAGIALTSLTSDSGIVGSFFAGFGIKIAYTRIGITVAMIFVGIPFVVRSVQPVLE
                     KMDNSYSEAAGVLGAKKTTIFWKVIFPELKPAIFAGTGLAFGRCLGEYGSVVFIAGNKP
                     YYTEITPLVIMSELQEFDYSSATAIALVMLAVSFFILFLNSMIQQRNARILRGGNA"
     CDS             2923..3747
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 59.2; E-value: 1.5e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg119_4"
                     /sec_met_domain="BPD_transp_1 (E-value: 3.6e-19, bitscore:
                     59.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNNEKTSEKITKWLLVGISVLFLAVMLLLPLITVITEALRSGWK
                     VYAAAVTDEYTIKALLLTVKATLFAVVFNTVFGVFAAWALTKFQFRGKKLLTTLIDLPV
                     TISPVIAGLIFLLIFGRQSPVYFFLMKLGIKVVFSVPGIIIATVFVTFPFISRELIPVL
                     EAEGSDEEEAAALMGAGGWTIFWKITFPHIKWALLYGVVLCTARAMGEFGAVSVLSGHL
                     RGKTNTLPLHVEILFNEFQYVPAFAVSSLLVIMAVIILVVRNLIEYKGKKEA"
     CDS             3749..4807
                     /locus_tag="ctg119_5"
                     /transl_table=11
                     /translation="MYVELKNINKTYGSYQASRNVNFGIEKGKLIGLLGPSGSGKTTIL
                     RMIAGLEIPDSGEVIIDGKVVNDVPASQRGIGFVFQNYALFRYMTVYDNVAFGLKVQKA
                     DKKKIDARVRELIKLVGLEGLEKRYPSQLSGGQRQRVAFARALAPNPQVLLLDEPFAAI
                     DAKIRQELRSWLKEMIGKLGITSIFVTHDQDEAIEVADEIIITNAGRIEQKGTPIGVYR
                     NPETAFTASFFGQPSVLKNADDFHTFAQAEGADKIIVRPEFVKISKLDEVEKFKTSVSR
                     GVVEQVSFRGDNLELQVRVNNSVVTARRSLEKADIREGETVNVFLYRIFALRGDSVQLI
                     ENEAVRDDFVII"
     CDS             4919..6664
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 71.4; E-value:
                     2.7e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg119_6"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.4e-23, bitscore:
                     71.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.2e-08,
                     bitscore: 25.0, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTERIRTDVLIIGGGTAGCFAAYVIGKKSGRKVLIAEKANIKRS
                     GCLAAGVNALNAYITEGRVPQDYVDYAKKDAHGIVREDLLLTMSERLNHVTKVMEDLGL
                     VILKDENGKYVARGNRNIKINGENMKPILAKAAAEQENVTVLNHVNITDYKTENKKVTG
                     AVGFSVNEDIFYDIDAKAVLCATGGAAGLYRPNNPGFSRHKMWYPPFNTGAGYAMGLLS
                     GAEMTTFEMRFIALRCKDTIAPTGTIAQGVGARQVNAHGDIYETKYGLTTSQRVYGTVM
                     ENREGNGPCYLRTEGISKEQEQDLYKAYLNMAPSQTLKWMEAGKGPSEENVEIEGTEPY
                     IVGGHTASGYWVDNNRATTIEGLYAAGDVAGGCPQKYVTGALAEGEIAAEAILEYLNGK
                     DDDRIAAENKEEALERGGEQELSQTAIAKKAEYESHLNASRSLMNAEQLEEAMQKIMDQ
                     YAGGIGTDYRYSGMSLAKADEKIAALLPVVDTLAATDTYELMQIYELRERLILCQAVIA
                     HLAARKETRWHSFGENTDYPQQSEEWMKYVNSRMENGEIKILYRDLITKENTGLNTAEK
                     GAGER"
     CDS             6661..6975
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg119_7"
                     /sec_met_domain="Fer4_9 (E-value: 2e-13, bitscore: 40.4,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 2.9e-09, bitscore: 26.9,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.9e-05, bitscore: 14.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIRIQKSKCAGCGRCIEACPGNLIKKDKENKAFIRQVRDCWGCT
                     SCIKECRHDAIRFFLGADVGGRGASMVVSEKPDISTWTVEKPDGTKITIQVNKKDANKY
                     "
     CDS             7006..8124
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAPS_reduct"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg119_8"
                     /sec_met_domain="PAPS_reduct (E-value: 4.5e-65, bitscore:
                     208.9, seeds: 27, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VCLKNALRKMCVTICGRFCSDEGVVAGYDNRIRTKYTAKWGVQIA
                     GMIFQTRSSVFAQVRKDSEYKQTEEDNAMSNVSHLDALEAEAIYIMREVAAECEKPVML
                     YSIGKDSSVMLHLAMKAFYPEKPPFPFLHIDTTWKFHEMIEFRDRIAKENGIDMLVYTN
                     EEGVKAGINPFDNGSAYTDIMKTQALKQALTKYGFTAAFGGGRRDEEKSRAKERIFSFR
                     NSAQAWDPKNQRPEMWKLYNTKIQKGESMRVFPISNWTEKDIWQYIQRENIEIVPLYFA
                     KERPVIYRDGNIIMVDDDRLKLRPGEKIENKKVRFRTLGCYPLTGGIESEADTLDEIID
                     ETLSAVSSERTSRVIDHEAAGSMERRKREGYF"
     CDS             8126..9766
                     /locus_tag="ctg119_9"
                     /transl_table=11
                     /translation="MKGLLKFITCGSVDDGKSTLIGHILYDAKLLYADQEKALELDSKV
                     GSRGGAIDYSLLLDGLMAEREQGITIDVAYRYFTTDNRSFIVADTPGHEEYTRNMAVGA
                     SFADLAVILVDASQGVLVQTRRHARICALMGIRYFVFAVNKMDLIEYDEKRFRDIENQI
                     AALIEELKLANVTIIPVSATEGDNVTTKSDNMPWYKGEALLSHLETVDIKEDTEKGFYM
                     PVQRVCRPNHEFRGFQGQIENGAIRAGDLVTTLPSKEEAHVKSILVGDKEVQEAVQGQP
                     VTIQLDREVDVSRGCVLTIDSGAVLTDSVEADILWMDDNALTDGKNFFVKIGTKMIPGL
                     VTKINYSVDVNTGEKKSAYTLKKNEIASCTLEFSEKIVVDEFDRHRTLGELILIDRVTN
                     MTSACGVVRKTFVSQDRSQIGKVDEQVRAGLKGQTPVVVEFPIGKEGITLDFAEQVEKG
                     LTVLGKHTYLYHPAASENYAETVRHLKAAGLIVLLVLDENTAKDETLKTLDGFYANWQI
                     DGITVKDAIDFVKKKSAFTVQSVHDGNYI"
     CDS             10436..10690
                     /locus_tag="ctg119_10"
                     /transl_table=11
                     /translation="MRLEKVQEALKTKKIHYEYTEENGCGSIDFMFRGLRFHIWEYEDR
                     VWGAETNVFEAGRSQDIEGDYEEIISGEILSWPDMLPGM"
     CDS             10663..10791
                     /locus_tag="ctg119_11"
                     /transl_table=11
                     /translation="MAGYAAWDVSMLLFTATHSRELGYVKSNVSITAEGNDIYEKI"
     CDS             10769..11551
                     /locus_tag="ctg119_12"
                     /transl_table=11
                     /translation="MIFTKKYRTGQIVLTACIAAVCMFSDVHGAEVAGPPAPKSKSALT
                     QKPEATPMPEATPIPASTPTPEQETETDKQNPADQGTLSKPDHPDTISADKLVFIGDSR
                     TEGLRDAVNDDSIWSCLSSMGYDWMVSTGVPQVEDQIEDNTAVIILMGVNDLYHVNDYI
                     SYINSKAAEWGNRGAQTYFVSVGPVQNDPYCSNAEIESFNAAMQASLSGVTYIDVYSHL
                     VSEGFSTVDGTHYPDSVSVDIYNYILDHLEEQMSGIWG"
     CDS             11817..13334
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg119_13"
                     /sec_met_domain="Fer4_7 (E-value: 1.3e-11, bitscore: 35.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.6e-11, bitscore: 33.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.4e-06, bitscore: 16.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGLYSSKTEIRHKIFTEIARMAYEGQSPEMLEELPYKIVPGEIA
                     TYRDSIFLERAVVGERLRVAMGMSLRKVTEHAPISKGVEASVIEEKYYEPPLINVIKFA
                     CNSCPEKRVMITEGCQGCLEHPCVEVCPKKAVHMEGGRSHIDEDACIKCGKCLEACPYN
                     AIIKQERPCSKACGMNAIGSDEYGRAEIDQDKCVSCGQCLVSCPFSAIVDKGQIFQTIM
                     ALKSETPVYAIVAPAIAGQFPGMENNKIRGAFQALGFTDVREVAVGADLCTVEEAKDFL
                     EEVPEKLPFMATSCCPSWSMMAKKLFPEQAKCISMALTPMVLTARLIKQKEPDCKIVFV
                     GPCAAKKLEASRKSIRSYVDFVLTFEEVAGMFDAKGVDWKDIPEGEPLFHASADGRGFA
                     VSGGVAEAVVHAVKRIDPDREVKVMNAEGLQNCKKMLQMAKIGKYNGYLLEGMACPGGC
                     VAGAGTIQTVKKAAAALEKMKKEASFTDAYDSKYRARLESLEKFDVE"
     CDS             13273..13398
                     /locus_tag="ctg119_14"
                     /transl_table=11
                     /translation="MPMTPNTEQDWKAWRNLMWSEILTESVKSYMDCKCLNAISI"
     CDS             complement(13506..14405)
                     /locus_tag="ctg119_15"
                     /transl_table=11
                     /translation="ERDTDRVRLSLPKTLKKYMEETYQIHENFLYLENKIFRGMDQIKQ
                     LRIYPPEKGSCKIIVVYEVPDQEELPQNGHELSIDLGLHNLMTCYDSENGNTFILGRKY
                     LGLERYFHKEIARVQAQWYGQQSGKGVKHPTTSKHIRKLYKRKHDSVTDYLHKVTRYLA
                     EYCREQGITCVIAGDIRNIRREKDLGHRTNQKFHSLPYNRIYIMLEYKLKRYGIRFIKQ
                     EESYTSQCSPLSPKVEKRYAEPSKRKERGLYRDGNRTYNADAVGAYNILRKYHSVSGVK
                     RELSVTGLKTPEIIKVAV"
ORIGIN
        1 ctgttcacac accactatcc cgcgaggtgt tttggcatga atatgccaaa atcccgagac
       61 atacaagcca aaattccatt gccgcaggca atctggaatg aattttggct acgttactgt
      121 gaacggagtg aacagtaacg ttccctgatt cacactgcag gtactgaaaa aatccttgac
      181 tttttttata acagtccgta taataatcaa cggtaaattt gtgaaacaga tatttggtat
      241 tattggaaac ggtacatcct cctggatggt tatgaacaac acaaatctct aattgatgtt
      301 attcatacta tctaaggagg attttttatg cctaaaaaca agtttcagga agttattttt
      361 acgattatca tggtgtttgt aatggtttat gccatgatct gctacaacat tgtactgaac
      421 acagggacaa tgacaaatga gacatttctg ttagcttttc atgaattaac attcatggga
      481 ccgattgcat ttattcttga tttctttatc atcggtggtc ttgcaaagaa gattgcattt
      541 ggtgttgtgg atatgagaag agataatccg ttccaccttg tacttgcaat ctcagcagta
      601 tccgttgcat ttatgtgtcc atgtatgagc tttgcggcaa ctgtgctgat caaacatgca
      661 ccggcaagtc agatcattcc cacatggctc cagacaacag caatgaactt tccgatggca
      721 ttcttctggc agatttttta tgccggacca ttcgtaagat ttattttcgg aaagcttttt
      781 ccggagaaag aaaaggcagc agcttctgcc gaataaaaaa tatgtaattt tgactgcagc
      841 attctgtatt tcaggatgct gcttttttgt gttcttatct acacaacata aattgtactt
      901 attttaatac actattgaca aattctgtca tttcttgtaa tatcatataa aacatatcga
      961 ataactatga aaagtagaga atgcaaaaaa ctactggtac cttaaaggag atgaaacatg
     1021 atcagaaaat tatttgcctt tggtcttgca gttgtactgg cactgatgcc ggtacaggct
     1081 tttggaaaaa cggtgtctat cactaatgtt tcctatgatc ctaccagaga gatgtttgaa
     1141 cagtataata aaatatttga agaccactgg aaggagaaga ccggggatga tgtggaagtg
     1201 atacagtccc atggtggttc agggaaacag gcacttgagg tagccaatgg tctggatgca
     1261 gatgtggtaa ccctggcact ggaatatgat atagagtcta ttgaaaatgc agggctgatc
     1321 aaggcaggat ggaaagataa atttgacaat gacagttctc cttatacatc cactatcgta
     1381 tttctggtga agaaaggaaa tcccagggat atcaaagact gggacgatct gacgaaaaaa
     1441 ggagtgggag tagtaacacc aaatccgaaa acctccggcg gtgccagatg gaactacatg
     1501 gcagcgtggg cttacgcaga taaaaagtat ggtggcgatg aagcgcagat gaaggaattt
     1561 attaagaaac tttaccggaa tgtggtggtt cttgactcag gcgcaagagg tgcaacgacc
     1621 tctttcgtgg agaacggaca aggagatgtg ctggttgcgt gggaaaatga agcttatcta
     1681 tccatgcggg attatccgga tgagtatgag attgttactc caagcgtaag tattctggca
     1741 cagccttctg tggcggtggt agatgaagtg gtggattaca gagatacaag agatgtggca
     1801 acagagtatt tgaattatct gtattccgac gaagcacagg agatcgcagc agagaattat
     1861 ttccgcccca ccaatgagaa aatcctgaag aagcacagta atacgtttga tctgaatata
     1921 aatctggcaa atatcagtga ttatggcgga tgggataaag tgcaggagaa acatttcaca
     1981 gatggcggaa ttttcgatca gatttatgag agataaagga agacaagatg aagcaagagc
     2041 ataagcacag acagaatata tgagacagga gaggtggtaa ttgattatga aaaaaagaaa
     2101 taaaccggtg attccagggt ttgggctctc catgggaatt accatttcca tattgagtct
     2161 ggtagttctg attcccctgg caagcctggt ggtctacaca gcgaagctga gttttaaaga
     2221 ttttatcgaa accatcacaa gggccagagt gctggcatcc ttttatacca gttttgtatg
     2281 tgcttttgca gcagcagtaa taaatggaat aatgggaact attcttgcgt gggtgcttgt
     2341 gaaatatgat tttccgggca agagacttat ggatgggatg atcgaacttc cctttgctct
     2401 tcccacagcg gtagcgggta ttgcactgac atccctgacc tcagattcgg gaattgtcgg
     2461 cagctttttt gcaggattcg gtatcaagat cgcatacaca agaataggta ttacagtggc
     2521 tatgatattt gtaggaatac cgttcgttgt gcgaagtgta cagccggttc tggaaaagat
     2581 ggataattct tacagcgagg cagcaggagt gctgggagca aagaaaacaa ctatcttctg
     2641 gaaggtcatt tttccggaac tgaagcccgc gatctttgcg ggaaccggac ttgcgttcgg
     2701 aagatgtctg ggtgaatatg gaagtgttgt atttatcgca ggaaataaac cctattatac
     2761 agaaatcaca ccgctggtta ttatgtcaga gcttcaggaa tttgattatt caagtgcaac
     2821 ggcaatcgca cttgtgatgt tggcagtttc atttttcatt ctgtttctta acagtatgat
     2881 acagcagaga aatgcaagaa ttttaagagg aggaaatgcc tgatggacaa caatgaaaag
     2941 acttcggaga aaattacaaa atggctgctt gtcgggatca gtgttctgtt tctggcagtc
     3001 atgctccttc ttcctctgat cactgtgatc acagaagcat tgcggagcgg atggaaggtc
     3061 tatgcagctg cagtgacaga tgagtacacc atcaaagcac ttcttcttac agtgaaggca
     3121 acactctttg cagttgtttt taacactgtt tttggtgttt ttgcagcctg ggcactgacg
     3181 aagtttcagt tcaggggtaa aaagcttctc actaccctga tcgaccttcc ggttactatt
     3241 tcccctgtta ttgcaggttt gatctttctt ctgattttcg gacgacagag tcctgtttac
     3301 ttttttctca tgaagttagg gattaaagtt gtattctctg taccgggaat cattattgca
     3361 actgtatttg taacctttcc ttttatttcc agagaactga ttccggttct ggaagcagaa
     3421 ggaagcgatg aggaggaagc ggcagccctg atgggagcag gtggatggac cattttctgg
     3481 aagatcacat tccctcatat caaatgggca ttactgtatg gagttgtgct ctgtacggca
     3541 agagcaatgg gagagtttgg agcggtatct gtactttccg gacatttaag aggaaagacc
     3601 aatacacttc ctcttcatgt agagattttg tttaatgagt ttcagtatgt tccggcgttt
     3661 gccgtatctt cgctgcttgt gatcatggca gttatcattc tggtagtcag aaacctgatt
     3721 gaatataaag gaaagaagga agcctgatat gtatgtagag ttaaaaaata tcaataagac
     3781 atatggttct taccaggcat caaggaatgt gaatttcgga attgagaaag gtaaactgat
     3841 tggtctgttg ggaccaagcg gaagcggaaa aacaactatt cttcgaatga tcgcaggtct
     3901 ggaaatcccg gacagcggag aggtcattat tgatggaaaa gtggtaaatg atgttccggc
     3961 cagtcagcgt gggattggat ttgtatttca gaattatgcg ttgtttcgct atatgacagt
     4021 ttatgataac gttgcatttg gtttgaaggt tcagaaggct gataagaaga aaattgatgc
     4081 cagagtcaga gagctgatca aactggtggg gctggaagga ctggaaaaaa gatatccaag
     4141 ccagttatct ggcggccaga ggcaaagggt ggcatttgcc agagcccttg ctccaaatcc
     4201 ccaggtgctg cttctggatg agccctttgc agccattgat gcaaaaatcc gtcaggaact
     4261 gcgaagctgg ttaaaagaga tgatcggaaa gctgggaatt accagtattt tcgttactca
     4321 tgatcaggat gaggccattg aagtagcaga tgagattatt atcactaatg caggacggat
     4381 cgaacagaaa ggaactccca taggggttta cagaaatcct gagacagctt ttacagcgtc
     4441 cttcttcgga cagccatctg tgttgaaaaa tgcggatgat ttccatacct ttgctcaggc
     4501 agaaggagca gacaagatta ttgtccgccc ggaatttgta aaaatctcca aactggatga
     4561 ggtggagaag ttcaaaactt ccgtatcccg gggagtggtt gaacaggttt ctttcagggg
     4621 agataatctg gaacttcagg tgagagtcaa caattccgta gtaactgcca gaagaagcct
     4681 ggagaaagca gatatccggg aaggtgagac tgtgaatgta ttcctttaca ggatttttgc
     4741 actgagaggt gacagtgtac agctgatcga aaatgaggct gtaagggatg actttgtaat
     4801 tatctgacag cggtggctgc ggcgactgac gataatgaag aaataagaaa ttcagacgca
     4861 agactgatcg ggaaatcaac ttgttggcac actggtatgg aggaaagggt aagagagaat
     4921 gagaacagag agaatcagga cagatgtgct gatcatcggc ggcggtacgg caggatgctt
     4981 tgcagcctat gtgatcggca aaaaaagcgg cagaaaagtt ctgatcgcag agaaagcgaa
     5041 tattaagcga agcggatgtc tggcggcggg cgtgaatgca ttgaacgcat atattacaga
     5101 aggcagagtg ccgcaggatt atgtggatta tgccaaaaag gatgcccatg gaatcgtaag
     5161 agaagacctt cttcttacca tgtcagagag actgaatcat gtgacaaagg tgatggaaga
     5221 tctggggctg gtcatcctga aggacgaaaa cggaaaatat gttgccagag gaaaccgaaa
     5281 catcaagatc aatggcgaaa atatgaagcc aatccttgca aaggcggcag ctgaacagga
     5341 gaatgttacg gttctcaatc atgtaaatat tacagattat aaaacagaaa acaaaaaagt
     5401 tacaggcgca gttggattta gcgttaatga ggatattttc tatgacattg atgcgaaagc
     5461 agttctttgt gccacaggtg gtgcagcggg actttacaga ccgaataatc cgggattttc
     5521 cagacataag atgtggtatc ctccgtttaa cacaggtgca ggatatgcaa tgggacttct
     5581 ttccggtgcg gagatgacaa cctttgagat gcgtttcatt gcattgagat gtaaggacac
     5641 gattgctcct acaggaacta ttgctcaggg tgttggggcc agacaggtca atgcacatgg
     5701 tgatatttat gaaacaaaat atggtctgac aacttcccag cgagtttacg gtacagtcat
     5761 ggagaacaga gaaggaaacg gtccatgtta tctcagaacg gaaggtattt ccaaagaaca
     5821 ggagcaggac ctttacaaag cttacctgaa tatggcaccg tcccagactc tgaaatggat
     5881 ggaagccgga aaaggaccat ccgaagagaa tgtagagatt gagggcacag agccatatat
     5941 tgtaggcgga catacagcca gcggttactg ggtagataat aacagagcta caactattga
     6001 aggtttatat gcagccggag acgtagcagg aggatgtccg cagaaatatg taaccggcgc
     6061 actggcagaa ggtgagatcg cagcagaggc gattttggaa tatctgaatg gcaaagatga
     6121 tgaccggatc gcagcagaaa ataaggaaga ggctttagag cgtggcggag aacaggagct
     6181 gtctcaaact gcaatagcta agaaggcaga atacgaatca catttgaatg cttcccgttc
     6241 tttgatgaat gcagagcagc ttgaggaagc catgcagaag atcatggatc agtacgcagg
     6301 aggaatcggt acagactaca gatacagcgg gatgagtctt gcaaaggcag atgaaaagat
     6361 cgcagcattg ttgccagtag ttgacactct ggcagcaaca gatacttatg aactgatgca
     6421 gatttatgaa cttcgcgaac gactgatctt gtgccaggca gtgatcgcac atctggcagc
     6481 cagaaaggaa accagatggc atagtttcgg agagaataca gactacccgc agcagagcga
     6541 agagtggatg aaatatgtaa actcccgtat ggaaaacggc gagattaaga tcttatatcg
     6601 tgacctgatc acaaaggaaa atacaggttt gaatacagca gagaaaggag caggtgagag
     6661 atgagcattc ggattcagaa aagtaaatgt gcaggatgcg gcagatgtat cgaagcctgt
     6721 cccggaaatc tgatcaaaaa ggataaagag aacaaagcct ttatccgtca ggtaagagac
     6781 tgctgggggt gtacttcctg tattaaggaa tgcaggcatg atgccatccg ctttttcctt
     6841 ggcgctgatg tgggaggcag aggtgcaagt atggttgtat cagagaaacc ggatatttcc
     6901 acatggacag tggagaagcc ggatggcact aagatcacta ttcaggttaa taagaaagac
     6961 gctaataaat attaaacata agtatgtact ctcagagtct ttagagtgtg tttgaaaaat
     7021 gctttacgca agatgtgcgt cacaatttgt gggagatttt gttcggatga gggcgtcgta
     7081 gcgggctacg acaaccgaat tcggacaaaa tataccgcaa agtggggcgt gcagattgcg
     7141 ggaatgattt ttcagacacg ctctagtgta tttgctcaag tacgaaaaga ttccgagtat
     7201 aaacaaacag aggaggataa tgcaatgagt aacgtatctc atcttgatgc gcttgaggca
     7261 gaggcgattt atattatgcg agaagtagca gccgagtgtg aaaagccggt tatgctctat
     7321 tctataggaa aggacagctc cgttatgctc catctggcga tgaaggcatt ttacccggag
     7381 aaacctccat tcccgttcct tcacattgat actacatgga aattccatga gatgatcgaa
     7441 ttccgcgaca gaatcgcaaa ggaaaacgga attgatatgc tggtttacac caatgaagag
     7501 ggtgtaaagg caggaatcaa tccatttgac aatggttctg catatacaga tatcatgaaa
     7561 acacaggcgt taaaacaggc tctgaccaaa tatggattta cagcggcatt tggaggcggc
     7621 cgccgtgatg aggagaaatc cagagcaaaa gagagaatct tttctttccg taattcagct
     7681 caggcatggg atccgaaaaa ccagagaccg gagatgtgga agctttataa cactaagatc
     7741 cagaagggag agagtatgcg agtattccca atttccaact ggacagaaaa ggatatctgg
     7801 cagtacattc agcgtgaaaa tatcgaaatt gtaccgttat attttgcgaa agaaagaccg
     7861 gtcatctaca gagacggaaa tatcattatg gtggatgatg acagattaaa actccgtccg
     7921 ggtgaaaaga ttgaaaacaa aaaagtcaga ttccgtactc ttggatgcta tccgcttact
     7981 ggaggtattg aatctgaagc agatactctg gatgagatta ttgatgagac gttaagtgct
     8041 gtttcttctg aacgtaccag cagggtgatc gaccacgagg cagcaggcag catggagaga
     8101 agaaagagag aggggtattt ctagaatgaa aggattattg aaatttatta catgcggaag
     8161 tgtggatgat ggaaaatcca ctctgatcgg acatattctt tatgatgcaa agcttctcta
     8221 tgcagatcag gagaaagctc tggagttgga ttccaaagta ggaagcagag gcggtgccat
     8281 tgattattct cttcttctgg acggtctgat ggcagagcgt gaacagggaa tcaccattga
     8341 tgttgcatac cgttatttta caacagataa cagaagcttc attgttgcag atacacccgg
     8401 acatgaagaa tatacaagaa acatggcagt gggtgcgtcc tttgcagatc tggcagttat
     8461 cctggtggat gcttcacagg gagtactggt acagacaaga cgtcatgcaa gaatctgcgc
     8521 attgatggga atccgttact ttgtatttgc agtaaacaaa atggatctta ttgaatatga
     8581 tgaaaaacgt ttccgcgaca ttgagaatca gatcgcagca ctgatagaag aactgaaact
     8641 tgccaatgta actattattc cggtatctgc cacagaaggt gacaacgtta caaccaaatc
     8701 tgacaacatg ccatggtata aaggtgaggc gcttctttcc catctggaaa ccgtagacat
     8761 taaggaagat acagagaagg gcttctatat gcctgtacag agagtctgca gaccaaacca
     8821 tgagtttcgc ggattccagg gacagattga gaatggtgcc atcagggcag gcgaccttgt
     8881 gactactctt cccagtaaag aagaagctca tgtaaagagt attcttgttg gcgataaaga
     8941 agttcaggaa gcggtacagg gacagcctgt taccatccag cttgacagag aagtagatgt
     9001 ttcccgcgga tgtgtactta ccattgattc cggcgcagtt cttacagact ctgtggaagc
     9061 agatatcctc tggatggatg acaatgctct tacggatggc aagaacttct ttgtaaaaat
     9121 cggtacaaag atgatccccg gcctggttac aaagatcaat tattctgtgg atgttaatac
     9181 aggtgaaaag aaaagcgcat ataccttaaa gaagaatgag attgcttcct gtactctgga
     9241 attctcagag aagatcgttg tagacgaatt tgacaggcac agaacactgg gtgagctgat
     9301 cctgatagat cgtgtcacaa atatgacttc tgcctgcggt gttgtgagaa aaacctttgt
     9361 ttctcaggat agatctcaga tcggaaaagt ggatgagcag gttcgtgcag gactgaaagg
     9421 tcagacaccg gtagtagtgg aattcccgat cggtaaagaa ggaatcactc ttgattttgc
     9481 agagcaggta gaaaagggac tgactgtact tggaaaacat acctatctgt atcatccggc
     9541 agcgagtgaa aactatgcag aaactgtccg ccatcttaag gcagcaggtc tgatcgtact
     9601 tcttgttctt gatgaaaata cagcaaaaga cgagacatta aagactctgg atggtttcta
     9661 tgcgaactgg cagattgacg gaattactgt gaaagatgcg attgatttcg tgaaaaagaa
     9721 atctgcattt acagtgcaga gtgtacatga tggaaattat atctgattat aacagggcta
     9781 taaatcgccg cagagacaaa gaaagtctct gcggtatttt gttttcttga caagtgtcgt
     9841 tacagcggat tatacttatt ttcaaatatc cagaatccat aataatacag acaggaaaga
     9901 taacagaaat atgcaaacga acaatgaaag taaacaaaac caaaaaaaga gatgatgctt
     9961 ggaactttgt ttgtaattgc tacgatcatc atcctggcga taccaacgaa gaaaagacag
    10021 aaataaagat gagtgaatat cgatcagaat gtagaatggg caattggtta ctgttcacac
    10081 accactatcc cgcgaggtgt tttggcatga atatgccaaa atcccgagac atacaagcca
    10141 aaattccatt gacacaggca atctgaaatg aattttggct aagttactgt gaacggagtg
    10201 aacagtaacg gcaattgtga agtggcattc agattacata ttatgcagca gagtatgata
    10261 taattcgttt tgtataatgg cgtcaggatt aagagcatat gtagagctgt gtagcgaagc
    10321 ggattgcgaa tatctgtttg acttttgatg ggtgtacacg agaacatttt tttacagtga
    10381 aagttatctg tattatatta cagaaggtac tgtacagata atcaggaggt attttatgcg
    10441 tttggaaaaa gtacaggaag cgttaaaaac aaagaaaatt cattatgaat atacagagga
    10501 aaacggatgc ggaagcatcg actttatgtt tcgcggtctg agattccata tatgggaata
    10561 tgaagatcgt gtctggggag cggagacaaa cgtgttcgaa gcaggcagaa gccaggatat
    10621 tgagggagat tacgaggaaa ttatttccgg agaaatcctc tcatggccgg atatgctgcc
    10681 tgggatgtaa gtatgttact gttcacagca acacactcca gggagttggg atatgtgaaa
    10741 agtaacgtaa gtattactgc agaagggaat gatatttacg aaaaaatata gaaccggaca
    10801 aatcgtatta accgcatgta ttgcagctgt ctgtatgttt tcagatgtcc atggggcaga
    10861 agtggcaggt ccgccggcac cgaaatccaa atcggcactg acacaaaaac ctgaagcaac
    10921 accaatgcct gaagcaacac caatacctgc atctactcca acaccggagc aggaaactga
    10981 gacagataaa cagaatccgg cagaccaggg aactttaagc aagccagacc atccggacac
    11041 tatctccgca gataaactgg tatttatcgg agattccaga acagagggat tgagggatgc
    11101 ggtaaacgat gacagcattt ggtcctgtct ttcttctatg ggatatgact ggatggtatc
    11161 tacaggagtg ccgcaggtag aagatcagat tgaggacaat acagcggtta ttatcctgat
    11221 gggtgttaat gatctttatc atgtcaatga ctacatcagt tatattaatt ccaaagctgc
    11281 tgaatggggg aacagaggag cgcagactta tttcgtgtct gtaggtccgg tgcagaatga
    11341 tccctattgc agtaatgcgg agattgaaag ttttaacgcg gcaatgcagg caagcctgag
    11401 tggagttacc tacatagacg tatattccca tctggtatct gagggatttt ccaccgtaga
    11461 cggaacccac tatccggaca gtgtgtccgt agatatttat aattatatct tggaccatct
    11521 ggaggaacag atgagtggaa tctggggata acaacatatg aacagcaact tcgggggcga
    11581 caattcagcg aaaattctga tgttgtgttg agcctggaag catttggtga tatgatatgc
    11641 agataaggaa acggaaatga gcggaatttc gtttctctgt gaagtggctg aaagttcagc
    11701 aggaggaaaa atgagtgtgc tgattgcagc agtgatgaaa ttataaatgg aaattgttcg
    11761 gtgtccctgc attggattgc cgtacagtta tccgaatcga aaatcaggag gaaaaaatga
    11821 gaggactgta ttcatccaaa acagaaatca gacacaaaat ttttacagaa attgcgagga
    11881 tggcatatga aggccagtct ccggagatgc tggaagagct tccctacaag atcgtacccg
    11941 gtgaaattgc gacttatcgt gacagtattt ttctggaaag agcggtagtt ggtgagagac
    12001 ttcgcgttgc aatggggatg tcactgagaa aggttacaga gcatgcgcca atttccaaag
    12061 gtgtggaggc cagcgttatt gaggaaaagt attatgaacc gccgcttatc aatgtgatca
    12121 agtttgcctg taattcctgc cctgaaaaaa gggtaatgat cacagagggc tgtcaggggt
    12181 gcctggagca tccctgtgtg gaagtctgtc caaagaaagc agtgcatatg gaaggcggca
    12241 gatcccatat tgatgaagat gcctgtatca aatgcggaaa gtgtctggaa gcctgtccgt
    12301 ataatgcaat catcaaacag gaacgtccat gttcaaaggc atgtggtatg aatgctattg
    12361 gctctgatga atatggaaga gcagagattg atcaggataa atgtgtatcc tgcggacaat
    12421 gtctggtaag ttgtccgttc agtgctattg tagacaaagg acagattttc cagactatta
    12481 tggcattaaa aagtgaaaca ccggtgtatg caatcgtggc gcctgccatt gcaggccagt
    12541 ttccgggtat ggagaataat aagatacggg gagcatttca ggcacttggc tttacagatg
    12601 taagagaggt tgccgtcggt gcagatctgt gcacagtgga ggaggcaaag gactttttgg
    12661 aagaagttcc tgagaaactt cctttcatgg ctacatcctg ttgtccgtcc tggtctatga
    12721 tggctaagaa attattcccg gaacaggcga aatgtatctc tatggcactg acacctatgg
    12781 ttctcactgc aaggctgatc aagcagaagg aaccagattg taagatcgtt ttcgtaggtc
    12841 cctgtgcagc caagaagctg gaagccagcc gtaagagtat ccgcagctat gtggattttg
    12901 tgctgacctt cgaggaagta gcaggaatgt ttgatgccaa aggcgtggac tggaaagata
    12961 ttccggaagg agaaccactg tttcatgcca gtgctgacgg aagaggtttc gcagtcagcg
    13021 gtggtgtggc agaagcggtt gtccatgcgg tgaagcgtat tgatcctgat cgggaagtaa
    13081 aggtaatgaa tgcagaaggt ctgcagaact gtaagaagat gctccagatg gccaagattg
    13141 gtaaatataa tggatatctt ttggaaggaa tggcatgtcc gggcggctgt gtagcaggtg
    13201 ccggtactat ccagacagtt aaaaaagcag cagcagctct cgaaaaaatg aagaaagagg
    13261 cttcgtttac agatgcctat gactccaaat acagagcaag actggaaagc ctggagaaat
    13321 ttgatgtgga gtgagattct gactgaatca gtgaaatcct atatggattg caagtgtttg
    13381 aatgcaatca gtatatagca gagtgaatta ctcggcaact gagttaccag agcatctgaa
    13441 ttaaggcggg ataccgcctt ttttcagggt gcatccatga caccactact gtttgctctt
    13501 tagagttata cagctacttt tattatttcc ggtgttttca gtccggttac ggacagttct
    13561 ctttttactc cggatacgga gtgatatttt ctcaggatat tatatgcgcc tacggcatct
    13621 gcattatagg ttctgtttcc atctctgtac aaccctctct ctttccgttt ggacggctct
    13681 gcatatcttt tctccacttt cggtgacagc ggactgcact ggctggtata actttcttcc
    13741 tgttttataa aacggatccc atatcttttc agcttatatt ccagcatgat gtagatcctg
    13801 ttatacggca ggctgtgaaa cttctggttt gtcctgtgtc ccaggtcttt ttctctccgg
    13861 atattccgga tatcccctgc aatgacacag gtgatcccct gttcccggca gtattctgca
    13921 agataccttg tgaccttgtg cagataatcc gttactgaat catgttttct cttatataac
    13981 ttcctgatat gttttgatgt ggtcggatgt ttgactccct ttccggactg ctgtccatac
    14041 cactgggcct gcacccttgc gatctcctta tggaaatatc tttccaatcc aagatacttc
    14101 ctgcccagaa taaacgtatt cccattttca gaatcataac acgtcataag gttgtgaagt
    14161 cccagatcaa tagacagttc atgtccgttc tgtggaagtt cttcctggtc aggaacctca
    14221 taaacaacaa taattttaca gcttcccttc tccggcggat agatccgcag ctgtttgatc
    14281 tggtccatgc ccctgaaaat cttattttca aggtaaagaa agttttcatg gatctgatat
    14341 gtttcttcca tatatttttt taatgtcttt ggaagggaca ggcggactct gtccgtatcc
    14401 cgctca
//
