LOCUS       gnlProkkaNOIGLDHJ_40    9653 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NOIGLDHJ_40.
ACCESSION   gnlProkkaNOIGLDHJ_40
VERSION     gnlProkkaNOIGLDHJ_40
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 02:54:24
            Original ID  :: gnl|Prokka|NOIGLDHJ_40
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9653
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9653
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4017:4281]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4018..4281
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..9653
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9653
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..1655
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 81.3;
                     E-value: 1.4e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg40_1"
                     /sec_met_domain="Pkinase (E-value: 2.4e-14, bitscore: 42.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELSNNMSLCMGCMQEIGDNKICPSCGFDTTEKQQAPFLPYGTIL
                     QNRYIVGAGIDTNGESTRYISHDKQTGDIVIICEFLPIGLFSREEGTTEVRINYENRLV
                     YNKLKDDFLNYYRILSELRELSALMNVHNIFEENNTVYVVEENEDLIPFEEYVERSNGH
                     LEWDIARPLFMPVISALEALHKRGVGHYAIAPKNMYITASGKIKISGFASENERKRGTP
                     LKSQLFSGAAAPEQYDDNFPLDDITDIYGFCATLFYALTGHMPKSAVERRKDSRLLMST
                     TTVKRLPPHVVSALANGLQVERENRITDFDELRSQLSVAHTAKAIQDEISRTASMNLTK
                     SERTRKTSNGMSHASIIIIAAAITVLVLGIAGVFWLMQNPLAGMFSNNTDASVSSTQST
                     EWTGATVPNYIGMTYEEAVKSVDSNSSITIYRTFNDEYSDDYAEGKIMSQTPAAGSKIT
                     QEDSVVVSVCVSKGSQMRTLPKVEGEKLDTVASDIAAQGLLATAEYEYSDKVAEGRVIR
                     YKEHVEGDTLEYGSTVVLIVSKGKKQTSSQSSN"
     CDS             1922..2206
                     /locus_tag="ctg40_2"
                     /transl_table=11
                     /translation="MTIKPLLDRVVLKVEEAEEKTKSGIILSSAAQEKPQFASVVAVGP
                     GGVVDGKEVKMYVSVGDKVIASKYAGTQVKIDGEEYTIVNQSDILATLE"
     CDS             2235..3863
                     /gene_functions="other (smcogs) SMCOG1299:chaperonin GroEL
                     (Score: 814.4; E-value: 5.8e-247)"
                     /gene_kind="other"
                     /locus_tag="ctg40_3"
                     /transl_table=11
                     /translation="MAKQIAYGEDARKALMKGIDQLADTVKITLGPKGRNVVLDKKFGA
                     PLITNDGVTIAKEIELEDPFENMGAQLVKEVSIKTNDIAGDGTTTATLLAQALIREGMK
                     NVTAGANPMVLKKGIADAVNVAVEAVKKNSKQVSGTDDIARVATVSSQDEFIGKLIAEA
                     MEKVTTDGVITVEESKTAETYSEVVEGMMFDRGYIAPYMVTDTDKMVAELDNPLILITD
                     KKISTTQEILPLLEQIVQMGKKLLIIAEDVEGEALTTLVLNKLRGTFTCVAVKAPGFGD
                     RRKEMLQDIATLTGGTVITSDLGLELKDTTVDQLGTARQVKIEKENTIIVDGSGDKEAI
                     KGRVAQIRQQIETTTSDFDREKLQERLAKLAGGVAVIKVGAATEVEMKEKKLRIEDALA
                     ATKAAVEEGIVAGGGIACMNAIPAVAEFVDTLEGDAKTGAKIVLKALEEPLRQIVANAG
                     LEGSVICDNVKKANKVGYGFNALTEEYTDMVSAGIVDPTKVTRSALQNASSVAAMVLTT
                     ESLVTDIKEPAAPAAPAAPDMGGMY"
     CDS             4018..4281
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_4"
                     /sec_met_domain="PF05402 (E-value: 6.6e-18, bitscore: 54.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.3e-14,
                     bitscore: 42.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKEDFVLRKVADSYVVVPVNKLTLDFNGIINLNETGAFLFEKL
                     QNDCEKADLLKAMLDEYEVSEEKASADIDTFIQKLREADVLE"
     CDS             4268..4756
                     /locus_tag="ctg40_5"
                     /transl_table=11
                     /translation="MFLNKEVGLDDVMQIIAEKLETGGSVTFNPKGTSMLPMLRDGDDT
                     VVLSKPKGRLHLFDLPLYRRKDGSYVLHRVVNFGSDGSYTMCGDNQFAVEKGITDDDVI
                     GVVTAFYRKGKSYTVDSMKYRAYLEFMFYSKPLRKVIASTVSRSKNAFSKLKTKKGKK"
     CDS             4753..5973
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg40_6"
                     /sec_met_domain="NTP_transf_5 (E-value: 2.7e-40, bitscore:
                     127.6, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKHLNDNEKIEFKYLLELVSSSVNGTAPPIPYEGIKWQSIKMLA
                     KYCSVESLVANAVLSLDKKYVSPEVYEKFKQNLSIEVLIDGNLSYETEKILKAFDENKI
                     KNIPLKGYFMKKEYPRPDFRSVSDVDILFDRKQADSVKKVFSKLGYAFLNEDDNQYHFE
                     KKPMMNIEMHATLVHENEESYPLLVNQLDRSTKRDGYSYSYEMSNEDFYIYMLVHNSNH
                     FRIGGMGARMVLDSYVFLKNHQSELDYDYLNVILEKIGIAKYEKRVREIAFNWFAKPQA
                     ELKFDDIEEYILLSGTLGRVDVGTMINSHKTITENNKSKFSYLVSSIFPPKSKMQYKYP
                     YVKKAPFLLPISWCHMWGKRLFADRDINFKSGIKNRMSYTDEDVNLYKSLLDEMGFDGI
                     GINNFGN"
     CDS             6079..6945
                     /locus_tag="ctg40_7"
                     /transl_table=11
                     /translation="MVRIITDSAADFEHSESEKFGISTVPLAVYIDGKEYKDDFLHSKE
                     RFYRLAKLSKTLPKTSQPSPYVYECALKKARDNGESVVVITVSSALSGSYQSAVLARDL
                     LGYEGCYVIDSKSASAGQKLLVNEALRLRDNGFTAKEIAEHLLRFRSKIMVYACIDDMK
                     YLYGGGRHTNAAALLGSTGRIKPVISITGSGSVAFEAKTIGMRHGMNHMLTSLKKLGID
                     QNYPLYIMHTNAKNQALYLSKLIISKGIPFVEGSIVSVGSVVGSHIGEGSTGIAFVKKE
                     QEKSGHD"
     CDS             complement(6967..8649)
                     /locus_tag="ctg40_8"
                     /transl_table=11
                     /translation="MGNTKAKNNSNKPKQTAKTVTSVKKQNTVEYVIVNILCLFVFIAF
                     AYIAIMSFVQTSVFDSANYGSEVILYQTDNIALNILFTSLFTVFIFKMKKHCDFFAKVN
                     LKYMHIGLAAFVMIVGLVWIFSVTSVPAADSYNIYETASQAAKGNYSSFHNNSGFYNSD
                     FYSGYSYYNFYPFQLGFVFISEIFYRIFGTDSTMPIQVFNVMCTAAAYIGIVNITRLLF
                     KKRSVEFITILLLAGCFQPVLFCTFVYGNIIGMCFAIWASYFLIKYFQTNKYLLLIPCA
                     VLLVISTLAKYNNLIYLVAFVVMLIIHTIKAKKWQSIAFALAICIAVVGTSNLVIMSYE
                     NRSGVKLSSGVSQAMYLDMGINDSYMAPGWYNGIALNDYKNAGLDAKAANAQAWTNIKS
                     RMNYFGKNTNYMIDFFSKKIISQWNEPTYESIWVSKVKSHTNELNWIGNGMYDGSIGQF
                     FELYFNFYMQILFIAFAAGIYFLFINRKTNIETVLLPLVILGAFGYHLLFEGKSQYVLT
                     YIILMIPTASFAFECILNGKYTKIKEFVGKLKEIPDGKESEKA"
     CDS             complement(8667..9629)
                     /locus_tag="ctg40_9"
                     /transl_table=11
                     /translation="MNISVLGCGRWGSCIAWYLDKIGHNVLSCGLADAPEFIQLKETHK
                     NDYLTFPKSIEVSSNLEYAIERAEVIIISISSQYLRSYFADISKYNLDGKTIVLCMKGV
                     EATTGKRLSEVVGEFVDESKTPVAVWVGPGHPQDYVRGIPNCMVIDSNNHDIKEKLVNE
                     FTSDLIRFYLGTDLIGSEIGAAAKNVIGIAAGMLDGLNYTSLKGALMARGTREIARLIK
                     ALGGNEMSAYGLCHLGDYEATLFSKWSHNRMYGESFAKGDRFTKLAEGVMTSKALYKLG
                     REYGVDLPIVESVYKVLFDGTDIKEALGTLFMRSVKKEF"
ORIGIN
        1 atttggagtt gagtaataat atgtcattgt gtatgggatg catgcaggaa ataggtgaca
       61 acaagatttg tccgtcctgc ggatttgata caactgaaaa acagcaagct ccttttttac
      121 cgtacggaac aattcttcag aaccgctata tcgtaggtgc gggaattgat accaacggcg
      181 aaagcacacg ctatataagc cacgacaagc agacaggtga cattgtaatc atctgcgaat
      241 ttcttcctat cggacttttt tctcgtgaag aaggaactac cgaggtcaga ataaattatg
      301 aaaaccgcct tgtatataat aaactcaagg acgattttct taactattac agaattcttt
      361 cagaactccg tgagctttcc gctcttatga atgttcacaa catttttgaa gaaaataaca
      421 cagtttatgt tgttgaggaa aacgaggatc ttattccttt tgaggagtat gttgaacgca
      481 gtaacggtca tcttgaatgg gatattgccc gtccgctttt tatgcctgta atttctgcgc
      541 ttgaggctct tcacaagaga ggtgtcggtc actatgctat cgcacctaag aatatgtata
      601 tcacagcatc gggtaaaatt aagatttcag gctttgcgtc ggaaaatgag cgtaaaagag
      661 gcacgcctct caaatctcag cttttttcag gcgctgcggc tcccgaacag tatgacgaca
      721 attttcctct tgacgatatt acggatatct acggattttg tgcaaccctt ttctatgccc
      781 tcacgggtca tatgccaaag agtgcggtag aacgccgtaa ggacagccga cttcttatga
      841 gtacaacaac tgtaaagaga cttcctccgc atgttgtttc ggctcttgct aacggtttgc
      901 aggttgagcg tgaaaaccgt attacggatt ttgacgagct tcgttcacag ctttccgttg
      961 ctcatacagc aaaggcaatt caggacgaaa tttcaagaac agcaagcatg aacctcacaa
     1021 agtcagagcg tacacgcaag acttcaaacg gtatgtcaca cgcttcaatt attattattg
     1081 cggctgctat cacggttctt gttctcggta ttgccggtgt gttctggctt atgcagaatc
     1141 cgcttgccgg aatgttttcg aataatactg atgcgagtgt aagctcaact caaagcacag
     1201 agtggacagg tgctactgtt cctaactata tcggaatgac atatgaagag gctgttaaga
     1261 gtgttgacag caacagcagt atcacaatct acagaacttt taacgatgag tacagtgatg
     1321 attatgcaga aggtaagatt atgtcacaga ctcctgccgc aggttcaaaa atcactcagg
     1381 aagattccgt agtagtgagt gtttgcgtaa gcaagggatc acagatgagg actctgccga
     1441 aggttgaggg tgaaaaactt gataccgttg catccgacat tgccgctcag ggacttcttg
     1501 caacagcaga atatgagtac agtgacaagg ttgctgaggg aagggtaatc cgctacaaag
     1561 aacatgttga gggtgatact ctcgaatacg gttcaacggt agttcttatt gtcagcaagg
     1621 gcaagaaaca gacaagttct caatcatcaa actgatataa ttaataacaa tgtttaagac
     1681 ggactttttg cagtcagtgt tttttattga tataaaacag ttatggttaa tgattatctt
     1741 aaaatactcg ataaaattga gattggaaaa aatttcagaa aactgtcaca aaataaaggt
     1801 caaaaatagt caaatttctc ttgacttttc ttgaaaatgg tataaaatat aattagcact
     1861 cagggaacaa gagtgctaat taattaaaag caatttaaaa tttttacagg aggctgtatt
     1921 tatgacaatc aaaccattac tcgacagagt cgttttaaaa gttgaagagg ctgaagagaa
     1981 aacaaagagc ggtatcattc tttcatctgc tgctcaggaa aagccacagt tcgcatcagt
     2041 tgttgctgtt ggccccggcg gtgttgttga cggcaaggaa gtaaagatgt atgtcagcgt
     2101 aggcgataag gttatcgcaa gtaaatatgc aggcacacag gtaaagattg acggcgaaga
     2161 atacacaatt gtaaaccagt cggatatact cgcaactctt gaataattaa ctaaatatac
     2221 ggaggtaatt tacaatggct aaacaaatcg catacggcga agatgcaaga aaagctttaa
     2281 tgaaaggtat cgaccagctc gctgataccg ttaaaatcac actcggacct aagggcagaa
     2341 atgttgttct tgataagaag ttcggtgctc cgctcatcac aaatgacggt gtaacaatcg
     2401 ctaaggaaat tgaacttgaa gatccttttg aaaatatggg tgctcagctt gtaaaggaag
     2461 tttctatcaa gactaacgat atcgcaggcg acggtacaac aactgccaca cttcttgctc
     2521 aggctctcat cagagagggt atgaagaatg taactgcagg cgctaaccca atggtactta
     2581 aaaagggtat tgcagacgct gtaaatgttg cagttgaggc tgtaaagaag aacagcaagc
     2641 aggtatccgg tacagacgat attgcaagag ttgcaacagt ttcatcacag gacgaattca
     2701 tcggtaaact tattgccgag gctatggaaa aggttacaac agacggtgtt atcacagttg
     2761 aggaatcaaa gacagccgaa acatacagcg aggttgttga aggtatgatg ttcgacagag
     2821 gttacatcgc tccttatatg gtaacagata cagataagat ggttgcagag cttgacaatc
     2881 cgcttatcct tatcacagat aagaagattt ctactacaca ggaaattctc ccacttcttg
     2941 agcagattgt tcagatgggt aagaagctcc ttatcattgc cgaagatgtt gagggcgagg
     3001 ctcttacaac tctcgtactt aacaaactca gaggtacatt cacttgtgtt gccgtaaagg
     3061 ctccgggctt tggtgacaga agaaaagaaa tgcttcagga tatcgcaaca ctcacaggcg
     3121 gtacagtaat cacatccgac cttggtcttg aactcaagga tacaacagtt gatcagctcg
     3181 gtactgcccg tcaggttaag attgaaaagg aaaacacaat catcgttgac ggctcaggtg
     3241 acaaggaagc tatcaagggc agagttgctc agatcagaca gcagattgaa acaacaacat
     3301 ctgactttga ccgtgaaaaa cttcaggagc gtcttgcaaa gctcgcaggc ggcgtagcag
     3361 ttatcaaggt tggtgccgca acagaagttg aaatgaaaga aaaaaagctc cgtattgagg
     3421 atgctcttgc cgctacaaag gctgctgttg aagagggtat cgtagcaggc ggcggtatcg
     3481 cttgcatgaa cgctattccg gctgttgcag agttcgttga cactctcgag ggtgacgcta
     3541 agacaggtgc taagattgtt cttaaagcac ttgaagaacc gcttcgtcag attgttgcta
     3601 acgcaggtct tgagggcagc gtaatctgcg ataatgttaa gaaggctaac aaggttggct
     3661 atggcttcaa cgctcttaca gaggaataca cagatatggt ttcggcaggt atcgttgacc
     3721 caacaaaggt tactcgttca gctctccaga acgcaagctc tgttgcagca atggttctta
     3781 caacagaatc acttgttaca gacatcaaag agcctgcagc tccggcagct cccgcagcac
     3841 ctgatatggg cggaatgtac taatcccgta agctgtaata ttatagataa attttaccgc
     3901 agactcaaaa ggtttgcggt aattttatgc tcaaatcctt tttcttgctt tttgtcgaaa
     3961 ggtatattat aatttaagca tgtacgaaaa aatttcacac ggaaaacagg tgattttatg
     4021 aagataaaag aagattttgt tctgcgaaag gttgcagatt catatgttgt agttccagta
     4081 aataagctga cgcttgattt taacggaatt atcaacctca atgaaacggg tgcattcctt
     4141 tttgaaaagc tccaaaacga ttgtgaaaag gctgatttgc tcaaagcaat gcttgatgag
     4201 tatgaagtga gcgaagaaaa ggcgagtgcc gatattgata catttattca aaagctaaga
     4261 gaggctgatg ttcttgaata aagaagtagg tcttgatgat gtaatgcaga ttatagccga
     4321 aaagcttgag accggaggat cggttacttt caatccgaag ggaacaagta tgctcccaat
     4381 gctccgagac ggtgacgata cggttgtttt atcaaaaccg aagggcagac ttcatctttt
     4441 tgacttgcct ttatacaggc gaaaagacgg ctcgtatgta ttgcaccgtg tcgtcaattt
     4501 cggaagtgac ggcagttata ctatgtgcgg tgacaatcag tttgccgttg aaaaaggtat
     4561 taccgatgat gatgtaatcg gagtggtaac agctttttac agaaagggca agtcctacac
     4621 ggttgactca atgaagtaca gagcatacct tgaatttatg ttctattcaa aaccgttaag
     4681 aaaggttatt gcatcaactg tgtcaagaag taaaaatgca ttttcaaagc ttaaaacgaa
     4741 aaaagggaaa aaatgaggaa acatcttaac gataacgaaa aaattgaatt taagtatctg
     4801 cttgagcttg tttcatcatc tgtaaacgga acagcacctc cgattcctta tgagggaata
     4861 aaatggcagt cgataaaaat gcttgcaaag tattgcagtg ttgaatcgct tgttgccaat
     4921 gcggttttgt cgctcgacaa aaagtatgtt tcgcccgagg tatatgaaaa attcaagcag
     4981 aatttgtcga ttgaagtgct gattgacgga aatctctcgt atgaaaccga gaaaattctc
     5041 aaggcttttg atgaaaacaa aatcaagaat attcctttaa agggctattt tatgaaaaag
     5101 gaatatcctc gtcccgactt tcgttccgtg tccgatgtag atatcctttt tgacagaaaa
     5161 caggctgatt cggtcaaaaa agtattttcc aaacttggat acgcttttct gaatgaagat
     5221 gacaaccagt atcattttga aaaaaagccg atgatgaaca ttgaaatgca tgcaactctt
     5281 gtccatgaaa acgaggaatc ttatccgttg cttgttaatc agcttgaccg ttcaacaaag
     5341 cgtgacggct acagctattc atatgaaatg agcaatgagg acttttatat ctatatgctt
     5401 gttcataact cgaatcattt cagaatcggc ggaatgggag caagaatggt gcttgacagc
     5461 tatgttttcc tgaaaaatca tcaatctgag cttgattatg actatcttaa tgtgatactt
     5521 gaaaaaatcg gtattgcaaa gtatgaaaag cgtgttcgtg agattgcgtt caactggttt
     5581 gcaaagccgc aggctgaact taaatttgat gatatcgaag aatatattct gctcagcggt
     5641 acactcggca gggtagatgt cggcacgatg ataaattctc acaagacgat tacagagaat
     5701 aacaaatcaa aattctcata tcttgtgtcc tcaatatttc ctccaaaatc caaaatgcag
     5761 tataagtatc cgtatgtgaa aaaagcaccg ttccttttac cgatttcatg gtgtcatatg
     5821 tgggggaaaa ggctttttgc agacagagat atcaatttta aatcgggcat caaaaaccgt
     5881 atgtcataca cggatgaaga tgtaaatttg tacaagtccc ttttggatga aatgggtttt
     5941 gacggtattg ggataaataa tttcggaaat tgaatatgca aatcaacctc ccgacagttt
     6001 ttgctgtcgg gatttttgta taataaaggc aaatttgaaa ataatatttc aagatattat
     6061 ttttgaggtg atacctaaat ggttagaatt attaccgatt cagccgccga ttttgaacat
     6121 tcagaaagtg aaaaattcgg aatttctaca gttccgttag ctgtatatat tgacggaaaa
     6181 gaatataagg atgatttttt acattcaaag gaacgctttt acaggcttgc aaagctgtcg
     6241 aaaactttgc cgaaaacctc tcagccctcg ccgtatgtct acgaatgtgc tttgaaaaag
     6301 gcgagagata acggcgaatc ggttgtggtg ataactgttt cttcggcatt gagcggttca
     6361 tatcagagtg cagttcttgc aagagatttg ctcggatatg aggggtgtta tgtgatagac
     6421 agcaaatctg cttcggcagg tcagaagctt cttgtaaacg aggcacttcg cctgcgtgac
     6481 aacgggttta cagcaaaaga aattgccgaa catcttctga ggttcagaag taaaattatg
     6541 gtatatgcct gtattgacga tatgaagtac ctctatgggg gtggcagaca tacaaatgcc
     6601 gccgcattac tcggctcaac aggaagaata aaacccgtaa tcagcattac gggttcgggc
     6661 agtgtagcct ttgaggcgaa aacaatcgga atgcgccacg gtatgaatca tatgctgacg
     6721 tcgctgaaaa agcttggcat agatcaaaat tatccgctgt atataatgca cacgaacgca
     6781 aaaaatcagg cattgtattt atcaaagctc ataatatcaa aaggaattcc ttttgttgag
     6841 ggcagtattg tcagcgtggg ttctgttgtc ggcagtcata taggagaggg cagtacgggt
     6901 attgcatttg tcaaaaaaga gcaagaaaaa agcggacatg attaactgtc cgcttcaatc
     6961 attttattag gctttttcgc tttctttacc gtcgggaatt tctttcagtt ttccgacaaa
     7021 ttctttgatt tttgtatatt tgccgttaag aatacactca aatgcaaaag acgcagtagg
     7081 aatcataaga attatgtaag tcagcacata ctgcgacttg ccttcaaata agaggtgata
     7141 tccgaacgct cccagaataa caagagggag aagtacagtt tcaatatttg tctttctgtt
     7201 aatgaacaag aagtaaattc ctgccgcaaa cgcaatgaaa agaatctgca tatagaagtt
     7261 gaagtacagt tcgaagaact gtccgatact gccgtcatac attccgttgc cgatccaatt
     7321 aagctcgttt gtatgagact tgaccttgct aacccatatg ctttcgtatg tcggctcatt
     7381 ccattggctg ataattttct tcgagaagaa gtcaatcata tagtttgtgt ttttaccgaa
     7441 gtaattcatt cttgatttta tattggtcca agcctgtgca tttgcggctt ttgcgtcaag
     7501 acctgcgttt ttataatcgt tgagggcaat tccgttgtac caaccgggag ccatatatga
     7561 atcgttaatg cccatatcaa ggtacatagc ctgtgaaaca ccgcttgaaa gcttcactcc
     7621 cgaacggttc tcataactca tgataacaag gttgcttgtt ccgacaacag caatgcaaat
     7681 tgcaagtgca aacgcaatgc tctgccactt cttagcctta attgtgtgaa taatcagcat
     7741 aacaacaaac gcaacaagat aaatcaggtt gttgtatttt gcaagtgttg aaataacgag
     7801 aagtacggca cacggaatga ggagcaggta cttgtttgtc tgaaaatact tgatgaggaa
     7861 gtatgatgcc cagattgcaa agcacattcc gatgatgttg ccgtaaacga atgtgcagaa
     7921 aagtacgggc tgaaaacagc cggcaagcag aagaattgta ataaattcaa ctgaacgctt
     7981 tttgaaaaga agtcttgtga tgtttacaat acctatataa gcggcagctg tacacattac
     8041 attgaatacc tgaatcggca ttgtactgtc cgtgccgaaa attctgtaga aaatttcgct
     8101 gatgaaaaca aagccaagct ggaacggata gaagttgtag taagaatatc cgctgtaaaa
     8161 atcgctgttg taaaaaccgc tgttattgtg gaatgacgaa tagttgccct tagccgcctg
     8221 cgacgctgtt tcatagatgt tgtagctgtc agccgcggga acagaggtta ccgagaatat
     8281 ccagacaagt cccacaatca taacgaatgc cgcaagacct atatgcatat atttcagatt
     8341 gacctttgca aaaaagtcac aatgcttttt cattttgaat atgaaaacgg taaacaggga
     8401 agtgaacagt atgttcagcg caatgttatc cgtctgatac aaaattactt cactgccgta
     8461 atttgccgaa tcaaacacgc ttgtctgcac aaagctcata attgctatgt atgcaaatgc
     8521 tatgaataca aacagacaaa gaatgtttac aataacatat tcgactgtat tctgcttttt
     8581 gactgaagta actgtttttg cagtctgttt aggtttattt gaattgttct tagctttagt
     8641 attacccata ttatgtacct gcccgcttaa aattctttct taacagaacg cataaacaga
     8701 gttccgagtg cttctttgat atctgttccg tcgaataaca ccttgtatac agactcaaca
     8761 atcggaaggt caacaccgta ttcccgaccg agcttgtata acgcttttga tgtcataaca
     8821 ccctcggcaa gctttgtaaa tctgtctccc tttgcaaagc tttcaccata cattctgttg
     8881 tgactccatt ttgaaaacaa ggtagcctca tagtcgccga gatgacaaag accgtaagca
     8941 ctcatctcat tgcctccgag tgccttaatg agtcttgcaa tctctcgtgt gcctcttgcc
     9001 attaacgcac cttttagcga ggtgtagtta agtccgtcaa gcatacctgc ggcgatgccg
     9061 ataacattct ttgcggcagc accgatttca ctgccgataa gatccgttcc aaggtaaaat
     9121 ctgataaggt cgcttgtgaa ttcatttaca agcttttcct taatatcgtg attattgctg
     9181 tcaataacca tacagttcgg aatacctctt acataatcct ggggatgtcc cggacctacc
     9241 caaactgcaa cgggtgtctt gctttcgtca acaaattcac cgacaacctc actgagcctt
     9301 ttgcctgtag ttgcctcaac acccttcatg cagaggacaa ttgtcttgcc gtcaagattg
     9361 tactttgaaa tatctgcaaa atacgaacgc agatactgcg atgaaatcga aattataata
     9421 acttcggctc tttcaatcgc atattcaaga ttcgaagaaa cctcaattga ctttggaaag
     9481 gtgagatagt cgtttttgtg tgtttcttta agctgtataa attcgggtgc gtcggcaagt
     9541 ccgcagctta aaacattgtg accgattttg tcgagatacc aggcaatgca gctgccccag
     9601 cgtccgcaac ctaaaacgga aatattcata ttattactac tcctgtttat ata
//
