LOCUS       c00016_gnlPro..         4023 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NOIGLDHJ_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:36:23
            Original ID  :: gnl|Prokka|NOIGLDHJ_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4023
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4023
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[501:3729]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      502..3729
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4023
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4023
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..209
                     /locus_tag="ctg16_1"
                     /transl_table=11
                     /translation="FDGNDKNISRAKYNEINLKQFNNCVNAHMFTKFIVTGYGDNSVWS
                     ENTTAENKQSLLDAYNSFSYEKY"
     CDS             complement(502..1542)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_2"
                     /sec_met_domain="IlvN (E-value: 2.5e-84, bitscore: 269.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.9e-61, bitscore: 194.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLK
                     DSGCDVIIGLYEGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKLAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(1603..2094)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_3"
                     /sec_met_domain="ALS_ss_C (E-value: 5.4e-31, bitscore:
                     94.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQDPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             complement(2107..3729)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.7e-44, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
ORIGIN
        1 attttgacgg taatgacaaa aatatttcac gggcaaaata taacgaaatt aaccttaaac
       61 agtttaataa ttgcgtaaat gcacatatgt ttaccaaatt tattgtgaca ggttatggtg
      121 ataacagcgt atggagtgag aatactacag ctgagaataa gcagtctttg cttgacgctt
      181 ataattcttt ctcctatgag aagtattgat tatttaaaaa ttaataagtt ttaactgcaa
      241 aagggttcag ccgtaaaaaa ctgaaccctt ttattgcaca acaaaaaaac ggttcagcca
      301 aattgactga accgttaatc tgtactatgt taagcttggg aacaagtagt tgtaaattat
      361 cacaaactac ctacacgaac tgcgggcgat gtactcgcaa aaagggtagc ttgaaaatca
      421 agctacccta aattcgtact atgtaacgct cgggtgacag aaatttgaat atatcaaact
      481 aacttcacga actaaaaaac attagttgtt gatgagctta tcttcgtcag accagctgta
      541 gagctttcta acttccttac cgaatacttc ggcaggagct tcggcagcga gctttctcat
      601 agccttgaag tgaacctgtg aaccggcatc gctcatgtca aggaggaagt ccttagcaaa
      661 tgtaccgtcc tgaatgtcag aaagaacctt tctcatagcc ttcttagtat cctctgtgat
      721 gatctttgga cctgtgatgt agtcaccgta ctcagctgtg ttagagattg aatatctcat
      781 gcctgcaaaa cctgactgat agataaggtc aacgatgagc ttcatctcat ggatacactc
      841 aaagtaagca tttcttgggt cgtaaccggc atcgcaaagt gtttcaaaac ctgcctgcat
      901 aagtgcgcaa acaccgccgc aaagaacagc ctgctcaccg aagaggtctg tttctgtttc
      961 tgttctgaat gttgtttcaa gaacgcctgc tcttgcaccg ccgataccga gtgcatatgc
     1021 aagtgcgaga tccttagcct gacctgtagc gtcctgctca acagcaacga ggcaaggtac
     1081 acccttacca acctgatact ctgaacgaac tgtgtgaccc ggtcccttag gagctaccat
     1141 tgtaacatca acatcctttg gaggcttgat gcaaccgaag tgaatgttaa agccgtgagc
     1201 gaacataagc atattgcctg cttcgaggtt tggctcgatg tcgttcttat aaagagctgc
     1261 ctgcttttca tcgttgataa gaatcatgat gatgtcagcc tgctttgcag cctctgccga
     1321 tgtatatacc ttaaagccct gagcttcagc ctttgcccag ctcttgctac cttcgtaaag
     1381 accgatgatt acatcgcaac ctgaatcctt gaggttgaga gcgtgtgcat gaccctggct
     1441 gccataaccg ataatagcaa ttttcttacc cttgagaagg tcaaggttgc aatctgactg
     1501 atagtagatt ggtgctgtca tgttctttgt gtagtctttc atattaaagt cctccttacc
     1561 gcaaacgcgg catataaatt agaatatatg ctaactgtaa gattaaacgg aaaccgaagc
     1621 tgtgcctctg tcaatggcaa cagtacctgt tcttacaatc tcacggatac cataaggctt
     1681 gagtaagtca acaagcgtgt tgatgcggct tgcacattcg cagtactcaa cggtaactga
     1741 cgaaggggat acatcaacga ttttcgcctg cataatttca accgttttga caatttcggc
     1801 tctttttgag gcggcgcagt gaaccttgat taatacaagc tcacggctga taaattcgcc
     1861 ctcgttaagc ctttttacct taataacggg aatgagcttg ttgagctgtt tttcaagctg
     1921 ttcaacaatg tactcgtcac cgtttgcaac gattgtgatt cgggaaaccg acgggtcctg
     1981 agtaacacct actgcaagtg agtcgatgtt aaaacctcgg cgagagaaaa gtcccgaaat
     2041 ctttgaaaga acgcccgcct gattttcaac aagtattgat aatgtatact gcattttatc
     2101 acctcattaa attgacggag tgtcggggtg aacatcgcaa acaagaatga acggtttttc
     2161 agaatcaaca atacccttga tgatgttttc ggcttccttg tttgaatgag cctctgcatg
     2221 gtcaatgccg taagcatcgg caatcttcaa gaagtcggga tcaccgttga gaattgttgc
     2281 ggagtgtctg ccgccgtagt gtttgtcctg aagttcacga accattccga gtcgtgcgtt
     2341 tttcataatg atgattttaa ttccgagctg attgcctgca atagtcgcaa gctcattaag
     2401 ccccatctga aaactgccgt caccgcagat tacaataaca tcacggtcgg gtcttgcaaa
     2461 ctttgcaccg attgcagcgg gaattgagta acccattgta cccataccgc ctgttgtgag
     2521 gaatctgccc tcacgaatac ggaagttgtt tgcacaccag atttgatttt gtcctacatc
     2581 ggcaacgaga attgcctttg agcggaacat cgcactgaga tgaccgacaa gtgttctcgg
     2641 ctcaacaaag ccgtcaaata cgggaggctc acggtaaagg tcttttttcc agttctttac
     2701 ggtttcgctc cacattgttg taaccttgta atcgccgata ctgtcaagca gcatattgat
     2761 gacatttttc atatcgccta caatcggaat ttccgtttta acattcttac cgatttcagc
     2821 agggtcaatg tcaatgtgaa ttacctttgt gttttcactc atctggtcgg gagctgcaac
     2881 agctctgtca ccgagtcttg caccacatac gattacaagg tcggcttcgt gaagagcacg
     2941 gttggcaaca gccttgccgt gagtgccgag cattccgaga taaagctcat gctcgctggg
     3001 cataacaccg atgcccatca tagttgaaat aacggggata cccgtagttt ctgcaaattt
     3061 ttgaagttta agcttgatac ccgaactcag cacgccaccg cctgatacga taacaggacg
     3121 cttgcttgcg ttgatggcct caacagcctt tttaacctga attgcgtgtc ccttggtgtt
     3181 cggcttgtaa ccgataatgt ttacgctttc gggatattca aaactttcaa tttcattttc
     3241 ctgaatatca acgggaatgt cgataagtac aggaccgggt ctgccggttg aggcaatatg
     3301 gaaagcctct ttgaaaactc tcggaaggtc ttctgttttg ctgacgagat aactgtgctt
     3361 tacaaacggt tcacaagctc ctgtgatgtc agcttcctga aagacatctc tgccgagaag
     3421 gtcggaacga acctgacctg taatggcaac aatcggaata gagtccgtat aggcggttgc
     3481 aatgcctgtg atgaggttgg ttgcaccggg accggaagtt gccacgcaaa caccgggacg
     3541 attactgcat cttgcatagc cgcttgccgc atgagcagcg ttctgttcct gacgaacaag
     3601 aatgtgggta atgctcgaat cgtaaacttt atcgtaaaat gggcagatag ccgcaccggg
     3661 ataaccaaag actatgtcaa cgccctcggc ttccaaacat tttaccataa tttcagcacc
     3721 gctgatcatt atgttttgtc cctcctatcc ttatttattg tgagcaaaag gtgttttgta
     3781 acattaaata tacctttttg ctttaccgct aattatacaa taaatacctt aaaaagtaaa
     3841 gagcagtatt gcccataaat taaatttttt gcaggatttt gacagataat ttgcaaaatg
     3901 gattttaatt gatttttacc gcctgtttac tgaaaattta agtcgcttag ttttgtaaag
     3961 tatattcttg gattaaggtt gctttttttg tctgcattat cagggaacat tattatcatc
     4021 aaa
//
