LOCUS       c00125_gnlPro..        16189 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GABJAGOC_125.
ACCESSION   c00125_gnlPro..
VERSION     c00125_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:58:56
            Original ID  :: gnl|Prokka|GABJAGOC_125
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 17340
            Orig. end    :: 33529
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16189
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[27340:30333]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12993
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16189
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16189
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             1051..1965
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg125_19"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.1e-30,
                     bitscore: 96.8, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEYTFSVFTPSYNRAKTLPRLYEALKRQTYRNFEWIIVDDGSAD
                     NTKETVEKFISDKPDFNITYKYQTNKGKHIATNVAAQIAKGEFFITIDSDDSVKDNALE
                     TFINEWNKIPDEDRSKYKGISCRTCNESGKTNGCPLPSERFDCSDLDLRLKYKIDGEMW
                     GMTKLKIIRANPYPCVSGLHFYPENIYWDNIGRKYITRFIDIPLRYYINDQENSLTGKA
                     YSAHRETIFVRLHFINECWDYAKSSPKFFIKQFVGLSRDGLLNGKRFSEIKKMPDTFSK
                     RALAVIFYPMGYFLYKKQSGGSR"
     CDS             1965..3044
                     /locus_tag="ctg125_20"
                     /transl_table=11
                     /translation="MKKVGIVTFHRALNYGAVLQSYALQKTVSSLGAECEIVDYICPKI
                     TADYKPFRIYKNDLLKSFAKSCVMVRRRAKRRDAFKSFFNNYLVKSKKSYTPQNIGELK
                     SDYDLFISGSDQVWSPRCVGFDPAYFLTFADDRQKYSYAASFAIPTLPDEFIDEYKKRL
                     NGFQKFSVREPSGEKLVKELTGRTAETHLDPTLLISADEWKKIAVSKIDKPYILIFTAN
                     PAVSLVDFALKLSKEKNLPVYCINDAPHPVSHGINYIVAPTVEEFVGCFKNAEYVVTNS
                     FHGTAFSVIFNKNLFVEFKNKSGRNIRSEGLLKSLGIDREIVDGNCRETEINWYDVNEK
                     IKNQTIISLDYLKSFVSGD"
     CDS             3220..4983
                     /locus_tag="ctg125_21"
                     /transl_table=11
                     /translation="MYSTIKSVQLLTALLKKYNINKLVLSPGGSDIPIIHSLENDDFFE
                     CHSVVDERSAVYYGIGLAQQTKSPVACICTSGTAVSNYLPGMTEAFYQDIPIVAITADK
                     DPYRLNQLMLQKTQQVNIFESVTKKSVNLPVVRGGNDRWYCERLINEALSELDHHGTGP
                     VHINIPIVENSAVYDCENLPQVRKINRISPDMPSEKWREYAERLSKYKKILVIAGQNNC
                     FSEDDRACIEKFFEKYNCLISVEHMSNLKCKGCLMTYPLSECSMQGMFGELCPDLIISF
                     GNNIASYKLKPMIKAHKEKFVHWQIDTAGRIRDFSDKLTDVFECTPQYFFNCFAENAPQ
                     DSKNDMTYYNMWNDDIKMLDYSSNLPFSNMYVAKKLAEVIPDRSVLHLAILSSTRTMQF
                     FDLKPNVKVYSNIGALGIDGCMSSFFGQASATDELAFCVVGDLSFFYDMNSAGIRGIKN
                     NARIILLNNGGGSEFHFFMGKEKIPTINQYICAEHHKGAKGWIESLGYDYYSATTKEEV
                     DNIIPTLAKESDRPIFVEIFTDMEEDAKLINRLFHDNRMKFGGMKLKMMEKAKSILSPS
                     QIQKAKKLLKK"
     CDS             4998..6182
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg125_22"
                     /sec_met_domain="UDPG_MGDP_dh_N (E-value: 3.1e-37,
                     bitscore: 119.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="UDPG_MGDP_dh (E-value: 5.6e-29, bitscore:
                     91.4, seeds: 679, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAIAGTGYVGLSNAVLLSQKHEVTAVDVVESKVRLINEKKSPI
                     ADREIEEYLADKKLNLVATVDAKSAYKNADFVIISTPTNYDDERHFFDTSSVEAVIELV
                     IECNPNAVIVIKSTIPVGYTKSVIEKYKYTKILFSPEFLREGKALYDNLYPSRIIVGVD
                     MANEELKKSAETFATALADCAIKENIDTLFMDYTEAEAVKLFANTYLAMRVSFFNELDT
                     YAEMKNLNTKSIIDGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLKANFSDVPNDIISA
                     VVTSNKTRKEFITSQIMNKNPKAVGIYRLTMKSNSDNFRQSSIQSVMELLKNNGIELII
                     YEPTLKVDLFEGFSVENDFEKFVTKSDVIVANRYSSVLDCVKEKVYTRDLFFRD"
     CDS             6198..7349
                     /locus_tag="ctg125_23"
                     /transl_table=11
                     /translation="METLIIGKPKIEKLDNRARLCSKISENGKPSYTLWFDVDAKYADY
                     LTESADAFVVALLPYAMNNSLNISAEAKMSKQLCFQLNEIFIPVLTKNSKLFNKISISA
                     KELTQENYCCKNASATGFSRGVDSFDTICSLSENSTEKLSHLTFFNVGSHRSTANYTPE
                     QSAELYENRLEIAKKSAKIFDMPLIDINSNLGEHLTLPYVKVHHYCSFSAVLCMQKFFK
                     NYYYASGYPISSFSIKQCDTGSAHYEAFTASMLSTESTAFYITGLEKTRLEKVDFISKF
                     PITYDNLNVCYYGENNCGHCEKCVRTQFELMALGKLELYKNVFDIPKFYRDKNKYMNYV
                     LKHQNKDYYAEILSLMKKKGFKLTPIQKIKKAVYAVYLKFRGN"
     CDS             complement(7570..7788)
                     /locus_tag="ctg125_24"
                     /transl_table=11
                     /translation="MDKNKKLFYTIIGAISALAAATAAFLALKKHRCAEQKLIEEIDDI
                     VSEKEPEEAAKEEPQAEVTADELAEEE"
     CDS             complement(7921..9774)
                     /locus_tag="ctg125_25"
                     /transl_table=11
                     /translation="MKSENIKKFGCVLLSAIMLSGISVCAVSAEEKSTEIHIVHTNDIH
                     GYYKSTSGGQIGFEAVKTIADKENADLILDAGDTFHGQSFATVEEGKSIAELMDAVGYD
                     AMTPGNHDWSYSADRLRELDRESSFTILASNVADTNGNRYFDNNFYIKNVTADDGTKVR
                     VGVFGVIDEDFYTSTSAKNVENVRFENSAETATAYANFLRDDENCDIILALTHNANPEK
                     FIAETSGIDAVIAGHQHILIDKYCTDSDGKSVKLVEANCFFKNVGVLTLTYSNEKGVTN
                     AVEKTYSSADTQGMSDEKIASDISAIEKREQSVLSEVIGESSREYAYSWEELRTSEQEI
                     GRIVTAAYLDFTGADVAMENAGGIRSGIPKGNVTYSDLISISPYGNVLVEKELTGQQII
                     DILEFSVDLMKKNNAVYDLQKQAIKDGEDPYQYSWPNNSGSVMQFSGLSAVYDYSKPYG
                     GRVSDVKIGEKAIDTLKTYRVVSNNYAFDSSDYGDVASLTTVKEYTTCEQILRDYIGKG
                     DFEKAAANANLVEKSSPSEEPTATQEQTVQTAPTGKPATVGTTSVNPTSATGGAATSDS
                     TPSQPDKNGGVQTGVTATAVMMLVVISGGVLFALAERKKRI"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 76.2;
                     E-value: 1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg125_26"
                     /sec_met_domain="Radical_SAM (E-value: 2.3e-30, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNAVKGFVHSIETFGSVDGPGVRFVIFLSGCAMRCQFCHNPDT
                     WKHDENTVEYTADELLNKALAYRPYWKNKGGITVSGGEPLLQIDFLLDLFKKAKKQGVN
                     TCIDTSANPFTTKEPFYSKWKELMEYTDLLLLDIKHIDNEQHKILTGQPNTNILEMARQ
                     LSDMGKPVWIRHVLVPERNDKDEYLFRLADFIHSLKNVERVEVLPYHTLGVYKWKALGY
                     DYPLEGINPPTKERVKNAEMILNGEKTRD"
     CDS             complement(10756..12993)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg125_27"
                     /sec_met_domain="Gly_radical (E-value: 3.4e-41, bitscore:
                     131.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 9.6e-272, bitscore:
                     893.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEWTNFAGGKWESDIDVRDFIQRNYTPYDGDQSFLEGPTEATD
                     KLWGELKELQKEERAKGGVLDMETEVVSGITAYGAAYLDKDLEKVVGLQTDKPLKRAFM
                     PYGGIKMAEQSCQMYGYTPSPKLHEIFTKYHKTHNQGVFDIYTPEMKLARHNKILTGLP
                     DTYGRGRIVGDYRRVALYGIDRLIEGKKEDFAETNRQGMRRGDFQLREEIADQIRALND
                     MKEMALSYGFDISQPAKNAAEAVQWLYFGYLAAIKTQNGAAMSVGRVSTFLDIYIERDL
                     ENGTLTESQAQELVDHFVMKCRMVKFARIESYNQLFSGDPVWATLEVAGLGIDGRSMVT
                     KNDYRFLHTLENMGPSPEPNLTVLYSSRLPENFKKYAAHISVTTSSIQYENDDVMRPVW
                     GDDYSICCCVSATQTGKEIQFFGARANLAKCLLYAINGGIDEKTKMQVGPEYTPITSEY
                     LDYDEVIKKYDTMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTDVRRTFATGIAG
                     FSHVVDSLSAIKYAKVKVIRDEDGIAVDFETEGDFPRYGNNDERADKIAVDLLKTFMAK
                     LKYCHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQNGLLA
                     SLNSVAKLPYEYALDGISNTQTINPGALGHNDDERVDNLVNVMDGYFDQGAHHLNVNVF
                     GTEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             complement(13260..13751)
                     /locus_tag="ctg125_28"
                     /transl_table=11
                     /translation="MKTDRVITAMIEYFGSDKKRIHHFLKVYSFAKTIGESENLLPDDQ
                     ELLEISAIVHDIGIKVSEEKYNSSAGKYQELEGPHEAEKLLAALGYEKTFIDKVCYLVG
                     HHHTYGNIDTLPYRILVEADFLVNLYEDDSSRSAAEQAYDKIFRTNTGKNLLKIMFLIP
                     "
     CDS             complement(13871..14407)
                     /locus_tag="ctg125_29"
                     /transl_table=11
                     /translation="MVIIMAHPIKHFRTITRHRHKVIANCARAGILRQGLIHDLSKYSP
                     TEFIPGAKYFQGTRSPNEKERELYGYSQAWMHHKGRNRHHYEYWNDYNPKTKQIENVEM
                     PVKYVIEMFCDRVAASKIYNGKNYTDGAPFTYFCRIRGKHRMHPNTEALLEKLLVMLRD
                     EGEEKTFAYIRSMKK"
     CDS             complement(14664..14897)
                     /locus_tag="ctg125_30"
                     /transl_table=11
                     /translation="MAEIRAVPSLRASTLPPSSTVTILLSELVHLVMDFAFSDDSSISF
                     DSPTFNVSESTLLGNVVFSVTAVSGVCGFGEF"
     CDS             14935..15759
                     /locus_tag="ctg125_31"
                     /transl_table=11
                     /translation="VAKSTAKKQQSYSTCITANLDKLESNKRNTAKNLYAIKVNRTANC
                     VTVYTYDEKGKYTIPVRAMICSTGLDNSTITGDYTIGIKSEWLFLVGDVFGRYISGISG
                     DYLFHSVPYYSMSEEDLELEEFNKLGEQASQGCVRLAVSDAKWVYDNCPTGTNVSIYDD
                     AENAGPLGKPDAIKITDFTNKWDPTDSNKKCPYAKATPTISGANDYTIKSGGEFYALAG
                     VTAVDTCGNDITSKIEVFGNVVTTRKGKYKVTYSVTDVLKRTSSVTITVTVQ"
     CDS             complement(15771..16085)
                     /locus_tag="ctg125_32"
                     /transl_table=11
                     /translation="VLSRNDFIIVAIGEHGSPLHYGNHFASYIKFVPIYNMCHYLRASD
                     ERPYRQTTTFIYKNSWEDDVLHFANRLPDIHFTFSILHFQFKISVRHLYFCFCGTIFLN
                     "
ORIGIN
        1 gcttgtagta attttgttct cgttttttcc cgcaaaagta tattttctcg ctatggcgtc
       61 acttgcaagc ggaatttttc ttttgcttac caatatcaaa gtcaagaaaa aaattcttcc
      121 tgaagtaaag atgaacttca accttttcag tttcaagctg gtaaaagttc tgatttccgc
      181 aggaatttgg tcgtcaatcg gttatctcag cacagctctg aacagaggtc ttgacctgtt
      241 aatctgtaac ctgactctcg gagcgggact catgggactt ttgtcgattg caaacaccgt
      301 tccgcactgc attgataact ttattacaac cattgcaaat atcttcactc ccagatttac
      361 aatcctttat gcaaagggca acacggactt acttgttgaa gaaacaaagt tttcgtcaaa
      421 gattatgagt tttctcatga ctgcacctct tgcgggattt attgcgtttg gcaacaagtt
      481 ctatacattg tggcagccga ccaaatctcc ggacgaaatt accataattc agattttgtc
      541 ggtgcttgtg tgtatttcat acctatttac ctgtcacaca agaactcttt ctagcctttt
      601 caccgtatgc aacaagctca aggcctccgt tcttatctcg cttgtgtgcg gtgttcttac
      661 ggttattatc gttttactgc tcatacactt tacaccgctc ggcgtttatg ctattgcagg
      721 cgtcagctct gtttttatcg gtcttaaagc gatagtattt gttccgttgt acgccgcaca
      781 tattttgaaa ataaagctta caacatatta caggtctatt ttcagaggat ggttctgctt
      841 tgctgttgtt atcaccatgt tcatctttat caacagcttt gtacacgcaa acagctggat
      901 atcattcctt cttttctgtg cagcaagcgg actggcagga tatgccgttt ccgttccgct
      961 cattttctca agaaaagaac tcgttcttat caaggataaa attaagaaga agtttaagaa
     1021 aagctaaatt attatcattt tgaggttgca atgactgaat atactttttc cgtttttaca
     1081 ccgtcatata acagggcaaa aactctgccc agattatatg aggcgctgaa aagacagaca
     1141 tacagaaatt ttgaatggat aattgttgat gacggttcag ccgacaacac aaaagaaacg
     1201 gttgagaaat tcatcagcga caaacccgac tttaatataa cctataaata tcagaccaac
     1261 aaaggaaaac acattgcaac aaatgttgcg gcacagattg caaagggtga attctttata
     1321 acgattgact ccgatgacag cgtaaaagac aacgcccttg aaacatttat aaacgaatgg
     1381 aacaaaattc ccgatgaaga caggtcaaaa tacaagggaa tttcatgccg cacctgtaac
     1441 gaaagcggca aaacaaacgg ttgtcctctg ccgtcagaac gatttgactg ttccgacctt
     1501 gacctgagat tgaagtataa aattgacggt gagatgtggg gaatgacaaa acttaaaata
     1561 atcagagcca acccctatcc gtgtgtttcg ggacttcatt tttatcccga aaatatctat
     1621 tgggacaata tcggaagaaa gtatataacc cgttttattg acataccgtt gcgatattac
     1681 ataaacgatc aggaaaattc tttgacaggt aaagcttact cggctcacag ggaaactatt
     1741 ttcgtaagac tccactttat aaacgaatgt tgggattacg caaagagcag ccctaagttc
     1801 tttatcaaac aatttgtggg actttcccgt gacggcttgc tcaacggcaa aagattttcc
     1861 gaaataaaaa agatgcccga cacattttca aagagggctc ttgcggtcat attttatccc
     1921 atgggatatt ttttgtacaa aaaacaatca gggggaagca gataatgaaa aaggtaggca
     1981 ttgtaacatt tcaccgtgca ttgaactacg gcgctgtgct tcagagctat gcgttgcaaa
     2041 aaaccgtttc ctcgctcggt gcagagtgtg aaattgttga ctatatctgt ccgaaaatca
     2101 cagccgacta caaacccttt cgcatttata aaaacgacct tctgaaatcc tttgcaaaaa
     2161 gctgtgtcat ggtaagaaga agagcaaaac gcagagacgc ttttaagtcg tttttcaata
     2221 actatcttgt aaagagtaaa aagtcgtata ctccgcagaa tatcggggag ctcaaaagcg
     2281 attatgactt gttcatttct ggaagcgatc aggtgtggag tccgagatgc gtcggttttg
     2341 atcccgctta ttttctgaca tttgccgatg acagacagaa gtattcatat gcggcaagct
     2401 ttgccattcc gacattgccc gatgaattta ttgatgaata taaaaaaagg ctgaacggtt
     2461 ttcagaagtt ctcagttcgt gaaccgagcg gagaaaagct tgtaaaagaa ctcacgggca
     2521 gaactgccga aactcatctt gatcctaccc tgctgatttc ggcagacgaa tggaaaaaga
     2581 ttgccgtttc aaaaatcgac aaaccgtata tcctcatttt tacggctaat ccggcagttt
     2641 cgcttgtgga ttttgccctt aaactgtcaa aagaaaagaa ccttcccgtt tactgcataa
     2701 acgatgcacc tcaccctgta agtcacggta taaattatat tgttgcacct actgttgagg
     2761 aatttgtcgg ctgtttcaaa aatgccgaat atgttgttac aaactcgttt cacggaacag
     2821 cgttttctgt tattttcaac aagaatcttt ttgttgaatt caagaacaaa agcggaagaa
     2881 acatccgctc cgaaggtctt ttgaaaagtc ttggaatcga ccgtgaaatt gttgacggaa
     2941 actgccgaga aaccgaaata aactggtacg atgtgaacga aaaaatcaag aaccagacaa
     3001 taatatcttt ggattatctt aaatcctttg tcagcggtga ttaaattgag tcttaaaaat
     3061 acactaaaaa aagtcagaca gggcataatc aaaaccttta aagcaaaaaa tgttgttccc
     3121 gtgtatgtac agaaggagaa caacaatatt cttaacggca aaaccgctct gattacaggc
     3181 ggttccggaa ttatcaaaaa ctaaagcgga ggaaagcgta tgtattctac aataaaaagc
     3241 gttcagttgc tcactgcact tctgaaaaaa tataatatca acaaattggt gctttctccc
     3301 gggggcagtg atattcctat aattcattca cttgaaaatg acgatttttt tgagtgtcat
     3361 tcggtcgttg acgagagaag tgccgtgtat tacggcatcg gacttgcaca gcagacaaaa
     3421 tcccccgttg cctgtatctg tacctcgggt acggctgtaa gcaactatct tccgggtatg
     3481 acagaggcat tttatcagga tattccgatt gtcgcaatta ccgctgacaa agacccgtac
     3541 agattaaatc agcttatgct gcagaaaacc cagcaggtca atatttttga atcggttaca
     3601 aaaaaatccg ttaatcttcc cgttgtgcgt ggcggaaatg acagatggta ctgcgaaaga
     3661 cttattaacg aggctctttc ggagcttgac catcacggaa caggacctgt gcatatcaat
     3721 attccgattg ttgaaaactc ggctgtatat gattgtgaaa atcttcctca ggttaggaaa
     3781 atcaacagaa tttctcccga tatgccctcc gagaagtggc gtgaatatgc agaaaggctt
     3841 tcaaaatata agaaaattct tgtcattgca ggtcagaaca actgtttctc ggaagatgac
     3901 agagcgtgca tcgagaagtt ctttgaaaaa tacaattgcc ttatatcggt tgagcatatg
     3961 tcaaacctca agtgcaaggg ctgccttatg acctatcctt tgtcagaatg ctcaatgcag
     4021 ggaatgttcg gcgagttatg ccctgatctt attatttcgt tcggcaacaa tattgcttca
     4081 tataaactca agcctatgat taaggctcac aaggaaaaat ttgttcactg gcaaattgat
     4141 actgcgggaa gaatcagaga tttttccgac aagctgacag atgtatttga atgtacaccg
     4201 cagtatttct ttaactgctt tgcagagaac gcaccgcagg attcaaaaaa tgatatgaca
     4261 tactacaata tgtggaatga cgatatcaaa atgcttgatt attcaagcaa tcttccgttc
     4321 tcaaatatgt atgttgccaa aaagcttgct gaagttattc ccgaccgttc tgttctgcac
     4381 cttgcaattc tcagcagtac aagaactatg cagttcttcg atttgaaacc gaatgtcaag
     4441 gtttacagca atatcggcgc tctggggatt gacggctgta tgtcttcgtt cttcggacag
     4501 gcatcggcaa cagacgagct tgccttttgc gttgtgggcg acctcagttt cttctatgat
     4561 atgaactccg caggcatcag aggaatcaag aacaatgcgc gaattattct tctcaacaac
     4621 ggcggcggtt cggaattcca cttctttatg ggcaaggaaa agattcctac aatcaatcag
     4681 tacatctgtg ccgaacatca caagggcgca aagggctgga ttgaatcact cggatatgac
     4741 tattacagcg caacaaccaa ggaagaagtt gacaacatta ttcctacact tgcaaaagaa
     4801 tccgaccgac cgatttttgt tgagattttc accgatatgg aagaggacgc aaagcttatt
     4861 aacaggcttt ttcatgacaa cagaatgaaa tttggcggaa tgaagctcaa gatgatggaa
     4921 aaggcaaagt caattctcag tccgtcacag attcaaaagg caaaaaaatt attaaaaaag
     4981 taatcaggtg aaaccaaatg aaaatagcaa ttgccgggac aggctatgta ggtctttcaa
     5041 acgctgtact tctttcgcag aaacacgagg taaccgctgt tgatgttgtt gaaagcaagg
     5101 taaggttaat caatgaaaag aaatctccga ttgccgacag ggaaatcgaa gaatatcttg
     5161 ctgacaaaaa attaaatttg gttgcaaccg tcgatgcaaa atctgcgtac aaaaatgctg
     5221 attttgtaat tatctctact cctaccaatt acgatgacga aagacacttt tttgatacat
     5281 cgtccgttga ggctgtaatt gagcttgtaa ttgaatgcaa cccaaatgcg gttatagtta
     5341 tcaaatccac tataccggtt ggatacacaa aaagtgttat tgaaaaatac aaatacacaa
     5401 aaattctttt cagtcccgaa tttttgcgtg agggcaaggc tctctatgat aacctctatc
     5461 cgtcaagaat cattgtcggt gttgatatgg caaatgaaga actgaaaaaa tctgccgaga
     5521 cttttgcaac ggcacttgca gactgtgcaa ttaaggaaaa catagacact ctctttatgg
     5581 actacacaga ggcagaggcg gtcaagcttt ttgcaaatac ataccttgca atgcgtgtca
     5641 gctttttcaa cgagcttgac acatatgccg aaatgaagaa ccttaacact aaaagtatca
     5701 ttgacggtgt gtgtcttgat ccgagaatcg gaaatcacta caacaatccg tcctttggct
     5761 acggcggtta ctgtctgcca aaggacacaa aacagctcaa ggccaatttt tcggatgttc
     5821 cgaatgacat aatcagcgct gttgtaacat ctaacaagac aagaaaagaa tttattacat
     5881 cacagataat gaataaaaat ccaaaagctg tcggaattta ccgccttaca atgaagtcaa
     5941 attccgataa cttcagacaa agctcaattc agagcgttat ggagcttttg aaaaataacg
     6001 gtatcgagtt aatcatctac gaaccgacac ttaaagtcga tttattcgag ggctttagcg
     6061 ttgaaaacga ctttgaaaag ttcgtcacaa aatcggatgt aatcgttgca aacagataca
     6121 gctccgttct tgactgtgta aaagaaaagg tttacacaag agatttgttt ttcagagatt
     6181 aatttgaggg taaaagtatg gaaacattga ttatcggcaa accgaaaatt gaaaaacttg
     6241 ataatcgtgc cagactctgt tcaaaaatca gcgaaaacgg aaagccttcc tacactctct
     6301 ggtttgatgt tgatgcaaag tatgctgact atctgaccga aagtgccgac gcattcgttg
     6361 ttgcgctgtt gccgtatgca atgaacaaca gtctgaatat ttcggcagaa gcaaagatgt
     6421 ccaagcaact gtgttttcag cttaatgaaa ttttcattcc cgttcttaca aaaaattcaa
     6481 aattattcaa caaaatttcg atatctgcaa aagagcttac acaggaaaat tactgctgca
     6541 aaaatgcgtc ggcaacagga ttttcgagag gtgtggattc atttgacaca atttgcagtc
     6601 tttccgaaaa cagcacggaa aagctgagtc atcttacctt tttcaatgtc ggctcccaca
     6661 gaagtacggc taattacaca cccgaacaat ctgccgagct gtacgaaaat cgtcttgaaa
     6721 ttgcaaaaaa atccgcaaaa atctttgata tgccgttgat tgacattaat tcaaatctcg
     6781 gtgaacatct tactctgccg tatgtaaagg ttcatcatta ttgcagcttt tcggcggtct
     6841 tgtgtatgca gaaatttttc aaaaactatt actatgcgtc gggatacccg ataagcagtt
     6901 tttcgataaa acaatgcgac accggctcgg cacactatga ggcatttacg gcaagtatgc
     6961 tgagtaccga aagtaccgct ttttacatta cgggtcttga aaagacaaga cttgaaaagg
     7021 ttgacttcat ttcaaaattt ccgattacat acgataacct caatgtgtgt tactacgggg
     7081 agaacaactg cggtcactgt gaaaagtgcg tcagaacgca gtttgagctt atggcactcg
     7141 gaaaacttga actgtataag aatgtttttg atattccgaa attttacagg gacaaaaaca
     7201 aatatatgaa ctatgttctc aaacatcaga acaaggacta ttatgcggaa atcctcagtc
     7261 ttatgaaaaa gaagggtttc aagcttacgc caattcaaaa aattaaaaag gctgtctatg
     7321 ccgtttatct taaattcaga gggaattaag gcttacggtt acttcgcaca aagcaaaaat
     7381 gcatcagacc ttttcgggca gctgatgcat tttctttttt aaactgtttt cttgaataga
     7441 ctgcggtggc acaccgccga catcattatc tgttttcaac tttcaattct taattgaaag
     7501 caccgctcga gtatttaact ttcgcatatg caaatactgc tacccgaatt tggtgcaaca
     7561 acttgttgct tattcttcct cagcaagctc atcggctgta acttctgcct gcggttcttc
     7621 ctttgcagcc tcctcaggct ctttttcgga aacaatatcg tcaatttcct caataagctt
     7681 ctgttctgcg catctgtgct tttttaaagc gagaaatgct gctgtggcag ccgcaagtgc
     7741 agagattgca ccgatgattg tgtagaataa ttttttgttt ttatccattc cggcacctct
     7801 ttcagtatta atataaatca gcggaaaaac cgtatttttc tacttattgc tattttatat
     7861 catttttaca aatttttcaa taggcaactg ataatctttg cacaaatggc tgtcagtgtt
     7921 ttatattctc tttttacgct ctgcaagggc aaaaagcact ccgcccgaaa ttacaacaag
     7981 catcataaca gccgttgctg tcactcctgt ctgaacaccg ccgtttttat caggctgtga
     8041 aggagtactg tccgatgttg cggcaccgcc tgttgccgaa gtcggattta cagaggttgt
     8101 accgacagtt gcaggcttac ccgtcggagc agtctgaaca gtctgttcct gagtagcagt
     8161 cggttcttcc gacggtgacg atttctcaac aagatttgca tttgcggcag ccttttcaaa
     8221 atcgcccttg ccgatataat cacgcagaat ttgttcgcag gtagtatatt ctttcacggt
     8281 cgtgagcgac gcaacatcgc cgtaatcgga actgtcaaac gcatagttat ttgaaaccac
     8341 tctgtaagtt tttaaagtgt caattgcctt ttctccgatt tttacatctg acactctgcc
     8401 gccgtacggc tttgaatagt catataccgc acttaaaccg ctgaactgca ttacagaacc
     8461 gctgttattg ggccagctgt actgatacgg gtcttcccca tcctttatcg cctgcttttg
     8521 aaggtcataa accgcattgt ttttcttcat aaggtcaact gaaaattcaa gaatatcaat
     8581 aatctgctga cctgtaagct ccttttcaac aagcacattg ccatagggtg aaattgaaat
     8641 caaatcggaa tatgtcacat taccctttgg aatacccgaa cggattccgc ctgcattctc
     8701 cattgcaaca tcagcaccag taaagtcaag ataagcggct gttacgattc tgcctatctc
     8761 ctgctcgctt gttctcagct cttcccagct gtaagcgtac tccctactgc tctcgccgat
     8821 tacttcgctg agtacgctct gttcacgctt ttcaattgca gaaatatcgg acgcaatctt
     8881 ttcatcggac atcccctgag tatcggcaga cgaatatgtt ttttcgaccg cattggtaac
     8941 gcccttttca ttggaatatg tcagagtaag cacacctaca tttttgaaaa agcagtttgc
     9001 ctcaacaagc tttacgctct tgccgtcact gtcagtacag tatttgtcaa tgagaatgtg
     9061 ctgatgacct gcgattaccg catcaatgcc tgatgtttcg gcaatgaatt tttcggggtt
     9121 tgcattatga gtcagcgcaa gtataatatc acaattctcg tcatctctga gaaaattcgc
     9181 gtacgctgtc gctgtttcgg ctgaattttc aaagcgaaca ttttcaacat tctttgccga
     9241 tgttgatgtg taaaaatctt cgtcaataac gccgaaaact ccgactctta cctttgtgcc
     9301 gtcatcagca gtaacattct ttatataaaa gttgttgtca aaatatctgt tgccgtttgt
     9361 gtctgccaca tttgaggcaa gtatggtaaa agagctttct ctgtcaagct ctctcagcct
     9421 gtcggcactg tatgaccaat cgtgattgcc gggtgtcatt gcgtcataac ctacagcgtc
     9481 cataagctcg gcaatgcttt ttccctcttc aacggtggca aatgactgtc cgtgaaaggt
     9541 gtcgcctgca tcaagtatca aatcggcatt ttccttgtcc gcaatggtct tgactgcctc
     9601 aaaaccgatt tgaccgcccg atgtggactt gtagtagccg tgaatatcat ttgtgtgaac
     9661 gatatgaatt tccgttgatt tttcttcggc agatacagca cacaccgaaa tgcccgaaag
     9721 cattatggca ctaagcaaaa cacaaccgaa tttttttatg ttttctgatt tcattacttt
     9781 actcctttca aattagaaat atgtagtaat tgtttgtaaa atcaatgctt tgttgggtga
     9841 attgtaccat attctgcgca atttttcaat agttttatat tgaatacggc agtaagctgt
     9901 tttattattg caaaattctg caaaagcaga ataacaaata aaaatcaaaa caaaaacggc
     9961 agtaccaaaa aaatcggtac tgccgttgtt atataagaaa ttaatctctt gttttttcgc
    10021 cgttaagaat catttccgca ttcttaacac gctcttttgt cgggggatta atgccctcga
    10081 gaggatagtc atagccgagt gctttccact tgtacacacc gagggtgtgg taaggaagaa
    10141 cctcgacacg ctcaacattc ttgagtgagt gaatgaagtc ggcaagtctg aaaagatact
    10201 cgtccttatc atttctttca ggcacaagaa catgtcttat ccatacgggc ttgcccatat
    10261 cggaaagctg ccttgccatt tcaagaatat tggtgtttgg ctgtcctgta aggattttgt
    10321 gctgttcgtt gtcgatatgc tttatatcca gcaacagcaa atccgtatat tccattagct
    10381 ctttccactt tgaatagaac ggctctttgg ttgtaaacgg gttggcactt gtgtcaatac
    10441 aggtattaac accctgcttt ttagccttct taaacaaatc aagcaaaaag tcaatctgta
    10501 aaagcggctc acctccgctt actgtgatac cgcccttatt tttccaatag gggcggtatg
    10561 caagcgcttt attaagcaac tcgtcggcgg tgtattccac ggtgttttca tcgtgtttcc
    10621 atgtgtcggg attgtggcag aactggcaac gcattgcgca accgctcaga aaaatcacaa
    10681 atctcacgcc cggaccgtca acagagccaa aagtttctat tgagtgtaca aagcctttaa
    10741 cagcgttgtc cgacattaca ttctgtcgtg gcaggttctg gcaataacat ccagctgctg
    10801 ctctcttgta aggtcgatga acttaacagc ataacccgat acacggattg tgaagttagc
    10861 gtactcttcc ttctcaggat gctccatagc gtcaatgagt ttttctgtac cgaatacatt
    10921 tacattgagg tggtgtgcgc cctgatcaaa gtagccgtcc ataacattta cgaggttgtc
    10981 aacacgctcg tcatcgttgt gtccgagagc acccgggttg attgtctgag tatttgaaat
    11041 accgtcaaga gcgtactcgt aaggaagctt agcaacagag ttaagtgaag caagaaggcc
    11101 gttctgctct gcaccgtagc ttgggttagc acccggtgaa agcggctcgc cggcttttct
    11161 gccgtcagga agtgaacctg tagccttacc gtaaacaaca tttgatgtga ttgtaaggat
    11221 agaagttgta ggctctgaat ctctgtatgt gtggcaatac ttgagcttag ccataaatgt
    11281 cttaagaaga tcaacggcaa tcttatctgc tctctcgtca ttgttaccgt atcttgggaa
    11341 gtcgccctct gtttcaaagt caacagcaat gccgtcctcg tcacggataa ccttaacctt
    11401 agcgtactta atagcgctga gtgagtcaac aacatgtgag aagcctgcga tacctgttgc
    11461 aaatgttctt cttacatctg tatcgataag agccatttct gctgcctcat agtagtactt
    11521 atcgtgcata tagtgaatca tattaagtgt gcctacatag aggtgagcaa gccaatccat
    11581 cattgtgtca tacttcttga taacttcgtc ataatcaagg tactctgatg tgataggtgt
    11641 atattcagga ccaacctgca tctttgtctt ttcatcaata ccgccgttga tagcgtagag
    11701 aaggcactta gcaaggttag ctcttgcgcc gaagaactgg atttccttac ctgtctgtgt
    11761 tgcggatacg cagcagcaga ttgagtaatc atcgccccat acaggacgca ttacatcatc
    11821 attctcgtac tgaattgagc ttgttgtaac tgaaatatga gcagcatact tcttgaagtt
    11881 ctccggaagt cttgaagaat aaagaactgt gaggtttggc tcaggtgaag gtcccatatt
    11941 ctcaagtgtg tggaggaaac ggtagtcgtt ctttgtaacc attgaacggc cgtcaatgcc
    12001 aagacctgca acttcgagtg tagcccatac agggtcgcct gagaagagct ggttgtaaga
    12061 ctcaattctt gcaaacttaa ccatacggca cttcataaca aagtggtcaa caagttcctg
    12121 agcctgtgat tctgtaagtg taccgttctc aaggtcacgc tcgatgtaga tatcgaggaa
    12181 tgttgataca cggccaacgc tcattgcagc gccgttctga gtcttgatag cagcaagata
    12241 accgaagtag agccactgaa ctgcctctgc agcgttctta gcaggctgtg aaatatcaaa
    12301 gccgtaagaa agtgccattt ccttcatatc gttaagagca cgaatctgat cggcgatttc
    12361 ttcacgaagc tggaagtcgc ctcttctcat accctgacgg tttgtttctg caaagtcctc
    12421 tttcttgcct tcgataagac ggtcaatacc gtaaagagca actcttctgt agtcaccaac
    12481 gattctgcct ctgccgtatg tgtcgggaag acctgtaaga atcttgttgt gacgggcaag
    12541 cttcatctcg ggagtgtaga tatcgaatac accctggttg tgagtcttgt gatattttgt
    12601 aaagatttcg tggagtttag ggcttggagt gtagccatac atctggcatg actgctcagc
    12661 cattttgata ccgccgtaag gcataaatgc acgcttgaga ggcttgtctg tctgaagacc
    12721 tacaaccttt tcaaggtctt tatcaagata tgcagcgccg taagctgtga tgccgcttac
    12781 aacctcagtt tccatatcaa gaacgccgcc cttggctctt tcttccttct ggagttcctt
    12841 gagctcgccc cagagcttgt ctgtagcttc tgtaggacct tcaaggaaag actggtcgcc
    12901 gtcataaggt gtgtagtttc tctgaatgaa gtctctgaca tcaatgtcgg actcccattt
    12961 gccacctgca aaatttgtcc attcttctct cattactgta aaacctccga taatgataat
    13021 taatactgaa ttttgtatat gacacaaaaa aatgccgact caattccaag cagacgcccg
    13081 gtaaggtcag ctccttgaaa aaatcgtcat acatccttgt attctgtcat ttattcactt
    13141 ttataatcat ataaccaaca ccattaaaat aacacttttt aagggcgttg tcaagcattt
    13201 tgagatactt tttacaccac tttttcacac tcaaaacact atggtaaatg agtacaattt
    13261 tagggtatga ggaacattat tttcagcaga ttttttcctg tatttgtgcg gaatattttg
    13321 tcatatgcct gctctgctgc actgcggctt gaatcgtcct cataaaggtt tacaaggaag
    13381 tctgcctcta ccaaaattcg gtacggcaaa gtatcaatat ttccataggt gtgatggtgt
    13441 cccacaaggt aacaaacttt gtcaataaat gttttttcgt agccgagagc agcaagcaac
    13501 ttttcagcct cgtgaggacc ttcaagttcc tgatactttc ctgcagacga attgtacttt
    13561 tcttcgctca cctttatgcc gatgtcgtga acgattgcgg agatttcaag aagctcctga
    13621 tcgtcgggca aaagattttc actttcaccg attgtctttg cgaatgaata aaccttgaga
    13681 aaatggtgaa tccttttctt gtcacttcca aaatattcaa tcatagcagt tataaccctg
    13741 tcggttttca tattatcact ccttacggcg agccgccgta ccctattcgt gtagacagtt
    13801 tttttgtttg tgcaattctg taggggtagc cttgcgacta tatttcagac gggaggattc
    13861 gcacaaacaa tcactttttc atacttctta tatatgcaaa ggtcttttct tcaccctcat
    13921 ctctcagcat aaccaataat ttttcaagca aagcctcggt gtttgggtgc atacggtgtt
    13981 tgcctctgat tctgcaaaaa tatgtaaacg gagcgccgtc cgtgtaattt ttgccgttgt
    14041 aaattttgct tgcggcaact cggtcacaga acatttcgat aacatatttt acaggcattt
    14101 caacattttc aatctgcttt gtctttgggt tgtaatcgtt ccagtattcg taatggtgac
    14161 ggtttctgcc cttgtgatgc atccacgcct gtgaatagcc gtacagttct ctttcctttt
    14221 cattgggact tctcgtgccc tgaaaatact ttgcacccgg aataaattct gtgggcgaat
    14281 actttgacaa atcgtgtatt aatccctgtc tgagaattcc tgctcttgcg cagttggcaa
    14341 ttaccttatg tctgtgacgg gttattgttc tgaaatgttt aatcggatgt gccataatta
    14401 tcaccataaa ttgttagttt ggaaaataca aaacattctc cgactgacat tttaccacat
    14461 ttcctgccga tttaaaatag cacttgcaag attgtcgaaa aaaagttata atatacaaag
    14521 gttaaaattt tgtaaccatt taatgttaaa ttctataagg ataggtaatc tatgaaaaag
    14581 aaaattttca ttcttttact ttgtgttgtc ctcattgcaa cctgcatatt atgcggtgtg
    14641 acgggaattt tcggaaatga ttctcaaaat tctccaaaac cgcagacgcc cgatacggca
    14701 gtaaccgaaa atacgacatt tccgagcaag gtcgattcgc tcacattaaa agtcggcgaa
    14761 tcaaagctta ttgaactgtc atccgaaaaa gcaaaatcca ttaccaaatg gacaagctcg
    14821 gacagtaaaa ttgttaccgt tgatgacggc ggaagggttg acgctctcaa agagggtacg
    14881 gctctgattt ctgccatttc aaaagacaaa tcaaagtcgg aatttcaggt tacggtggca
    14941 aaatcaactg cgaaaaaaca gcaaagctac tcaacctgta taacggcaaa tcttgacaag
    15001 cttgaaagca acaagcgtaa tacggcaaaa aatctgtacg caatcaaggt caaccgcacg
    15061 gcaaactgcg tgacggttta cacgtatgac gaaaagggca agtacacaat ccccgtaagg
    15121 gcgatgattt gctccacagg tcttgacaat tcgacaatca cgggtgacta cacaatcgga
    15181 atcaagtccg aatggctttt ccttgtgggc gatgttttcg gaagatacat cagcggaatt
    15241 tcgggcgatt atcttttcca ctccgttccc tactactcaa tgagcgaaga agatttggag
    15301 cttgaggagt tcaacaagct tggcgaacag gcgtcacagg gttgcgtaag gcttgcagtt
    15361 tcggatgcaa agtgggttta tgacaactgc cccacaggca cgaatgtaag catatatgac
    15421 gacgcagaaa atgcaggccc tctcggaaaa ccggatgcaa tcaaaatcac cgattttacc
    15481 aacaaatggg atccgacaga cagcaataaa aaatgtccgt atgccaaagc aacaccgaca
    15541 atcagcggtg caaacgatta cacaatcaaa agcggaggcg aattttatgc ccttgccgga
    15601 gtaacagccg ttgacacctg tggcaacgac ataacatcga aaatcgaagt tttcggcaat
    15661 gtggtaacca cccgaaaagg caagtacaag gtaacatatt cagtcaccga tgtgcttaaa
    15721 agaacatcaa gcgtaacgat tacggtaacg gtgcaataaa cacgttgcag tcaatttaag
    15781 aagatagttc cgcaaaagca aaaataaaga tgccgaacgg agattttaaa ttgaaaatgt
    15841 aaaattgaaa atgtaaaatg aatgtcggga agacggtttg caaaatgcaa aacatcgtct
    15901 tcccaactgt ttttatatat gaaagttgtt gtttgtctgt aggggcgttc atcggacgcc
    15961 cgcaagtaat ggcacatatt atatattgga acaaacttta tatatgacgc aaaatgattg
    16021 ccataatgta gcggcgaacc gtgttcgcca atcgcaacga ttataaaatc gttgcgactc
    16081 agcacaaatt atttgtttat taacatatca tttttatata ataaaaactg tgtatatgtt
    16141 cgatttgttt ttgcaaacaa accgattggc gaacacggtt cgccgctac
//
