LOCUS       gnlProkkaHNDODLHM_38   10749 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HNDODLHM_38.
ACCESSION   gnlProkkaHNDODLHM_38
VERSION     gnlProkkaHNDODLHM_38
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 02:57:20
            Original ID  :: gnl|Prokka|HNDODLHM_38
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10749
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10749
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[1104:3303]"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1105..3303
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
     cand_cluster    1..10749
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /kind="single"
                     /product="HR-T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10749
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="HR-T2PKS"
                     /region_number="1"
                     /rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /tool="antismash"
     CDS             134..820
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141:acyltransferase (Score: 82; E-value: 6.5e-25)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_1"
                     /transl_table=11
                     /translation="MEYNYHKNTGQLAFIKFVNGLVHLLIRPEVEWKDKSLKKSLKGKP
                     VVFVCNHTHHFDGVVISSVLSRYKPYMLVKKSWYNKSGTGSFIRICRSIPVDFDTMDTN
                     WYAQSDGAVENGYSMLIFPEGGIARDGKMLPFKPGAALLAAKKGLDIIPIASLGEYKIL
                     FGKRQKILIGNPIKSECPENVRCSKYAKEISAEAEKQVKKLYLELEEKYGKGKVYYKED
                     FSSENL"
     CDS             861..1103
                     /NRPS_PKS="Domain: PP-binding (6-75). E-value: 1.1e-11.
                     Score: 37.0. Matches aSDomain:
                     nrpspksdomains_ctg38_2_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_2"
                     /sec_met_domain="PP-binding (E-value: 2.9e-12, bitscore:
                     37.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNTIADQIKEMLVENLRIPENILTYDSELFGDEIGLDSIDSIEI
                     VAGIDTLFGIDMTGADREHFQSIRALTEYVESKQG"
     aSDomain        879..1085
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_2_PP-binding.1"
                     /evalue="1.10E-11"
                     /label="ctg38_2_PP-binding.1"
                     /locus_tag="ctg38_2"
                     /protein_end="75"
                     /protein_start="6"
                     /score="37.0"
                     /tool="antismash"
                     /translation="DQIKEMLVENLRIPENILTYDSELFGDEIGLDSIDSIEIVAGIDT
                     LFGIDMTGADREHFQSIRALTEYV"
     CDS             1105..3303
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (66-399). E-value:
                     2.7e-50. Score: 163.3. Matches aSDomain:
                     nrpspksdomains_ctg38_3_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: hr-t2pks-ksa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 80.1; E-value:
                     2.7e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_3"
                     /sec_met_domain="hr-t2pks-ksa (E-value: 3.4e-106, bitscore:
                     345.4, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="t2fas (E-value: 7.8e-23, bitscore: 70.8,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADKKRCVVTGLGLICGVGDNVKDCWDAVTLGHSGIDEVKSVDTS
                     NCYAHKGAEVDKASSELSPENYDRSSLLCIHAANEAFEDANIDASEKNIGVILGSCVGG
                     AASIDKYYTDEIKGDGGKKEDIFKMGASAIANNVSAHFGLEGITANIVNACAAGTMSIG
                     YACDLIREGKGDVFIAGGSDSFSSLAFSGFHALHALDKNACSPFNHSTGITLGEGSGIL
                     VIESYEHAVERGAKIYCEILGSGVSSDAYHITAPRPDGEGQMSAIRRAVESSALSFDDI
                     DYINAHGTGTAKNDEAEFLSLHTLFDGNDHLSVSSTKSMTGHCLGAAGSIEAVFSVKAI
                     KENLVPPTIGYSDEDLKMLSEKAGNIDFIPNKSHTKDVHYAMSNSFAFGGNNASIIFSD
                     NEHDIPDNSKNEKIYITGISKLTGTRTDEHSLNCNLTSEDYDKHGIKVAFYRKLDRFSQ
                     LQLLSGMDALADADIKIDKDNEYKTGIVIGTADGPMTEIVDFQKKAITRGTEKGSAFSF
                     PNTVYNAAGGYLSIFSGIKGYNATVANGNQAGLQSICYAADILADGNESVMLAAGTDEN
                     TKTNLELYTKAELLEKPLGEGSVTLVLETEESANGRNARKYAEIKGYAQAHRPVSYDNS
                     EVDSKAVVEVIEKACVNAGIEADNIDFVCCDDRKIIKTLMPCYDVSQEIGNARAAASAM
                     TAAYAAELLSDSEKNYEYGLALSMGAGGTYSAVILKKA"
     aSDomain        1303..2301
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_3_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.70E-50"
                     /label="ctg38_3_PKS_KS.1"
                     /locus_tag="ctg38_3"
                     /protein_end="399"
                     /protein_start="66"
                     /score="163.3"
                     /tool="antismash"
                     /translation="YDRSSLLCIHAANEAFEDANIDASEKNIGVILGSCVGGAASIDKY
                     YTDEIKGDGGKKEDIFKMGASAIANNVSAHFGLEGITANIVNACAAGTMSIGYACDLIR
                     EGKGDVFIAGGSDSFSSLAFSGFHALHALDKNACSPFNHSTGITLGEGSGILVIESYEH
                     AVERGAKIYCEILGSGVSSDAYHITAPRPDGEGQMSAIRRAVESSALSFDDIDYINAHG
                     TGTAKNDEAEFLSLHTLFDGNDHLSVSSTKSMTGHCLGAAGSIEAVFSVKAIKENLVPP
                     TIGYSDEDLKMLSEKAGNIDFIPNKSHTKDVHYAMSNSFAFGGNNASIIFSD"
     CDS             3319..4053
                     /NRPS_PKS="Domain: PKS_KR (3-167). E-value: 2.7e-16. Score:
                     51.8. Matches aSDomain: nrpspksdomains_ctg38_4_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     226.8; E-value: 4.7e-69)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_4"
                     /sec_met_domain="adh_short (E-value: 3.5e-40, bitscore:
                     127.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 4.7e-35, bitscore:
                     111.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTALVTGSSRGIGKACALKLAELGYDIAVNCNSNLEMAQKAVD
                     EITSLGRKAVAYKANTADIDEVKDMFRNIQQDFGGIDVLVNNAGVVDDAYLLMIKDESL
                     ERSLDINIKGYFNCARQASLKMLRKKNGIIINISSVSSVLAVEGQSVYSATKGAVNAMT
                     HTLAKELAKYGIRVNAVAPGFIETEMMNGIPEELQKKYLEAIPEKRFGTVQDVANVVGQ
                     LCSDDFSYMTGQVLVLDGGLSL"
     aSDomain        3328..3819
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_4_PKS_KR.1"
                     /evalue="2.70E-16"
                     /label="ctg38_4_PKS_KR.1"
                     /locus_tag="ctg38_4"
                     /protein_end="167"
                     /protein_start="3"
                     /score="51.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGSSRGIGKACALKLAELGYDIAVNCNSNLEMAQKAVDEIT
                     SLGRKAVAYKANTADIDEVKDMFRNIQQDFGGIDVLVNNAGVVDDAYLLMIKDESLERS
                     LDINIKGYFNCARQASLKMLRKKNGIIINISSVSSVLAVEGQSVYSATKGAVNAMTHTL
                     A"
     CDS             4050..4505
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1270:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine
                     (Score: 92.9; E-value: 3.7e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_5"
                     /transl_table=11
                     /translation="MMNLLEINQRIKQRPPFQMIERVTELEPNVSATGIKNVSVNEPYF
                     AGHFPDTPIMPGVLLIESAAQLCSLVFAPESVEEDKLYVLLKVKDFKMLRPVIPGDTLI
                     ISVNVTMSTKSAFEFACVIKVDGEVRAKGNLLFTTMDKNAVYKPSQE"
     CDS             4508..5212
                     /locus_tag="ctg38_6"
                     /transl_table=11
                     /translation="MKVLVLNGSPKGEKSNTLNITKAFLDGFSADTEVEYITVKKETIK
                     PCMGCFSCWSRTPGKCVIKDDMQKIYEKINSADIIIESFPLYFFGMPSQMKALTDRCLP
                     YMLPYSGNVVEDKEASFHELRDEAMHEKRLLVITTCGYVSAEPMYPALIKQLDLICGNG
                     NYTMIKCPEGELFIAEKAERQRKAYLDSITEAGREFCENRCLCDETMKKISKPILSPKG
                     FEAITKAHWKMS"
     CDS             complement(5213..5782)
                     /locus_tag="ctg38_7"
                     /transl_table=11
                     /translation="MTDLRIVKTRTNIKNSLIDLLAEKNVSKITVTELAEKAMINRKTF
                     YRHYNTVQDVVDDINYDIINDVISHAKKSDRDGNNLVNQLNFIGLSIVENKEQINKILK
                     NSPEVFGSGRSVELLKRFIEVSIRPVLNFKNETKLKYLVEFVVSGFISVYVRWFNDGCA
                     ESSEKLADAVNEFVLGALSEYVRPKS"
     CDS             5859..6698
                     /locus_tag="ctg38_8"
                     /transl_table=11
                     /translation="MTGLIIEGGARRGIFTAGITDCLLENKIHFDYVAGVSAGAEVALD
                     FTAKQEGRSRRVIMPHRTGDFSVLGFLSMDLDNMIYRFPYQDYPFDFDTFFASDTNCEF
                     VATDCVTGKAKYFSENKSEQRLLDSVRASCTVPILYQISEFEGGKYVDGSIADAVPFDR
                     AFEQGCSRVLVLLTKPENEPCTDYRKFEFLINKKYKDYPNLINALMTRFDRYNEQCKRM
                     KQLEEDGILMVLRPSHKYVKSFEMNTDVLDEAYNAGKNLAKERLAEIEDFLNVLEKK"
     CDS             6894..7433
                     /locus_tag="ctg38_9"
                     /transl_table=11
                     /translation="MKKQLMIFDFVCFGIGAIFLTFVAILQNCGINITNGSVIGIVITV
                     LLFTLILLSTANVLGFDCTVSNITFLRPILLFIALYIFYCMPFMGFIGKAGNVWNSIMF
                     AHFGITVSRQFYYISKSPIAEKFVKSPFVYTKGTEFFSSAGSFFKFLSVIIIPMTVIGI
                     ILNITTNGINVASIFS"
     CDS             7585..8034
                     /gene_functions="regulatory (smcogs)
                     SMCOG1171:transcriptional regulator, MerR family (Score:
                     81.8; E-value: 1.4e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg38_10"
                     /transl_table=11
                     /translation="MYTIGQVSQMCGIPVSTLRYYDKEGLFPHMERVSGIRRFSDRELE
                     TLRIIDCLKKSGLEIREIRKFMQWCSEGSSSYPQRRELFENQKKTVEKEIERLQKTLDM
                     LRFKCWYYDTAIADGNEDRINEMLPNNLPEDIQKLYDHAHSDDED"
     CDS             complement(8101..8292)
                     /locus_tag="ctg38_11"
                     /transl_table=11
                     /translation="MKYPELSCDVYAEVDGENVLLIEIDREGRAKVYHENLRIDGVRKI
                     FEEINCNIESYIKYFGTK"
     CDS             8431..8913
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 86.4;
                     E-value: 3.1e-26)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg38_12"
                     /transl_table=11
                     /translation="MPFEEFYRQNFKTVYGFLINLCKNSDLAEELTAETFLKAFEHYKS
                     YNKKYKPSTWLCAIAKNEYLKYLRKQKKIDGFDNAEIADISNLEEKLSDKDTALRIHKY
                     LHILDEPYREVFILKVFAELSYKEIAEIFGKKETWVRVTYYRAKVRLLERLGDDNE"
     CDS             8867..9616
                     /locus_tag="ctg38_13"
                     /transl_table=11
                     /translation="MQKSDYWKGLVMIMNKNCNIVRDLIPLYSDNTASDESRKFIEEHC
                     RTCDKCNRILSLSKTEIDKTAHLDDEINSVWKSIEKQNKKKRIIKVAIAAILVTVLIPL
                     IIIGANYMYGADNTDTAKSPYFSDEMLNEFDKGYSQSDQKQLEPLLNDIKNVIDFNGEY
                     ETAKGKFGELAYYSYDRVEGDYTVKAKVELNSAKLYTDTGYMWIEYTKDLYTDDGTFWM
                     TTKPVKSRITVINKDGEWTAVNIQSEQ"
     CDS             9677..10087
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275:peptide deformylase (Score: 127.2; E-value:
                     6.8e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_14"
                     /transl_table=11
                     /translation="MVREIVHDPMFLQRKSEDATQADLQTAQDLLDTLRANFDRCVGMA
                     ANMIGVAKKIIAINDNGKYLVMFNPEIISKFGEFETEEGCLSLDGERKTVRYKTIKVKY
                     FNENFKQIKRSFTDFTAQIIQHEIDHCNGILI"
     CDS             10355..10747
                     /locus_tag="ctg38_15"
                     /transl_table=11
                     /translation="MKEITKNQATAIWQIFFVLWLTVGSIVCFNLGCIEDSPICTPMFA
                     ITPLYIIEFYFDHPYTVQAIMFQNFVLILMPALLWFLTYKSVFKNKKSANTIILILMIP
                     DTVLSAFYGLFFTIGYFFTSNHYFLLL"
ORIGIN
        1 ccataataat tcccatatat tttatgccac aaaatttgac agaatgttgc ataaaccaca
       61 cgcaaatttc atttgcccgt tgaatttttt taaaataaaa atataatatt ttaaaaaaac
      121 gagggtaaag agtatggagt acaattatca taaaaataca ggacagcttg cattcataaa
      181 atttgtaaac ggtcttgtgc atcttcttat tcgcccggag gttgaatgga aggacaagag
      241 ccttaaaaag agcctcaagg gcaagcctgt cgtgtttgta tgcaaccaca ctcaccactt
      301 tgacggagtt gtgataagct ctgtactcag cagatacaag ccgtatatgc ttgttaaaaa
      361 aagctggtac aacaagagcg gaacaggctc gtttatccga atttgccgca gtattcccgt
      421 tgactttgac accatggaca caaactggta tgcgcaaagt gatggtgcgg ttgaaaacgg
      481 atattcaatg cttatcttcc ccgagggcgg aattgcaaga gatggcaaaa tgctcccgtt
      541 caagcccggt gcggcattgc ttgcagcaaa aaaaggtctt gacataatcc cgattgcatc
      601 tttgggtgag tataaaattc tttttggaaa gaggcagaaa attttaatcg gcaatccgat
      661 aaaatccgaa tgtcccgaaa atgttcgctg ctcaaaatat gcaaaagaaa taagtgccga
      721 ggccgaaaag caggtcaaaa agctttatct tgagcttgaa gaaaaatacg gcaaaggcaa
      781 ggtttattac aaagaagatt tttcttcgga aaatttataa taaaatcaaa aaaatcaaat
      841 ttttaagtga ggtaattaaa atgaacaata ctattgcaga tcagattaag gaaatgctcg
      901 tagaaaacct tagaattccc gaaaacattc ttacatacga ttcagagctt ttcggtgacg
      961 aaatcggtct tgactcaatc gactcaatcg aaatcgttgc aggcatcgac acacttttcg
     1021 gtattgatat gacaggtgca gaccgtgagc acttccaatc aatcagagca cttacagaat
     1081 atgtagaaag caagcagggt taatatggct gacaaaaaga gatgtgttgt cacaggactc
     1141 ggacttatct gcggcgtcgg tgacaatgta aaggattgct gggatgccgt aacactcggt
     1201 cactccggca ttgatgaggt taagtcggtt gacacctcaa actgttatgc acacaagggt
     1261 gcagaggttg acaaggcatc gtcagagctt tctcccgaaa actatgaccg ttcttccctt
     1321 ctctgtattc atgccgcaaa cgaggctttt gaagatgcaa acattgacgc atccgaaaag
     1381 aacatcggtg ttattcttgg cagttgtgta ggcggtgcgg caagcattga caaatattac
     1441 acagacgaaa ttaagggtga cggcggtaaa aaagaagata ttttcaaaat gggtgcttca
     1501 gcaattgcca acaatgtttc cgctcatttc ggacttgagg gcattaccgc aaacatagtc
     1561 aacgcttgtg cggcaggcac aatgagcatc ggctatgcct gtgaccttat ccgtgagggc
     1621 aagggtgatg tgttcattgc aggcggttcg gacagctttt cttcacttgc attcagcggt
     1681 ttccacgctc tccatgcgct tgacaaaaac gcctgttccc cgttcaatca cagcacaggt
     1741 atcacgctcg gcgagggttc gggtattctt gtaatcgaaa gctacgaaca cgctgttgaa
     1801 cgaggtgcaa agatttactg tgaaattctc ggttcgggtg taagcagtga cgcttaccac
     1861 attaccgctc cccgtcccga cggcgaaggt cagatgagtg caatcagaag ggctgttgaa
     1921 agctctgctc ttagttttga cgatattgac tacataaacg cacacggaac aggtactgcc
     1981 aaaaatgacg aggctgaatt tctttcactt cacacacttt ttgacggcaa tgaccacctt
     2041 tctgtcagct caacaaaatc tatgacaggt cattgtctcg gtgcggccgg ctcaattgag
     2101 gctgtatttt ccgtaaaagc aataaaagaa aacctcgttc cccctacaat cggctactcc
     2161 gatgaggatt tgaagatgct ttccgaaaag gcgggcaaca ttgactttat tccgaacaag
     2221 agccatacaa aagatgttca ctatgcaatg tcaaactcat ttgcattcgg cggcaacaac
     2281 gcaagcatca ttttctcgga caacgagcat gatattcccg acaacagtaa aaatgaaaaa
     2341 atttacatta cgggcatttc aaagcttaca ggcacaagga ctgacgaaca cagccttaac
     2401 tgcaatctta cctccgagga ttatgacaaa cacggaatca aggttgcatt ttacagaaag
     2461 cttgaccgtt tcagccagct ccagcttttg agcggtatgg acgcacttgc agacgctgac
     2521 ataaaaattg acaaagacaa cgaatataaa acaggtattg taatcggcac ggctgacggc
     2581 cctatgaccg aaattgttga tttccagaaa aaggcaatca caagaggtac tgaaaagggc
     2641 agtgcttttt cattcccgaa tacggtttac aatgccgcag gcggttatct aagcattttc
     2701 tcaggcatca agggctacaa cgcaactgtt gcaaacggca atcaggcagg actgcagagt
     2761 atttgctatg ccgctgatat tcttgcagac ggcaacgaaa gcgttatgct tgccgcaggt
     2821 accgatgaaa atacaaagac aaaccttgaa ctctatacaa aggccgaatt gcttgaaaaa
     2881 ccgctcggtg agggctctgt aactctcgtt cttgaaacag aggaaagtgc aaacggcaga
     2941 aatgcacgca agtatgcaga aattaagggt tatgcacagg ctcaccgccc tgtatcgtac
     3001 gacaactcag aggttgacag caaggctgtt gttgaggtta tcgaaaaggc ttgtgtgaat
     3061 gccggcattg aggcagacaa tatcgacttt gtatgctgtg acgacaggaa gattatcaag
     3121 acacttatgc cctgctatga tgtatcgcag gaaatcggca atgcaagagc cgcagcaagt
     3181 gcaatgacag cggcatatgc ggctgagctt ctttctgaca gcgaaaaaaa ttacgaatac
     3241 ggacttgctc tttcaatggg tgcgggcgga acatactctg ccgtaatcct gaagaaagcg
     3301 taaaaatcgg aggtaaatat gagcaaaacc gctcttgtaa caggttcatc aaggggcatt
     3361 ggcaaggctt gcgctttaaa gcttgcagag cttggatatg acattgccgt gaactgcaat
     3421 tcaaatttag aaatggctca aaaggctgtt gacgaaatta catcactcgg cagaaaagcc
     3481 gttgcctaca aggcgaacac ggcagatatt gacgaagtaa aggatatgtt ccgcaatatt
     3541 cagcaggact ttggcggaat tgatgtgctt gtcaacaacg caggtgtggt tgacgacgct
     3601 taccttttga tgattaagga cgagtcgctt gaaagaagtc ttgacattaa tatcaaagga
     3661 tatttcaatt gtgcaagaca ggcatcgctt aaaatgctcc gcaaaaagaa cggaatcatc
     3721 atcaacattt cttccgtaag ctctgttctt gcagttgaag gtcagtcggt ttacagtgca
     3781 acaaagggtg cggtaaacgc tatgacacac acgcttgcaa aggaacttgc aaagtacgga
     3841 atcagagtaa acgcagttgc gcccggtttt atcgaaaccg aaatgatgaa cggcattccc
     3901 gaagaattgc aaaaaaagta tcttgaggct attcccgaaa agagattcgg cacagttcag
     3961 gatgtcgcaa atgtagtcgg acagctttgc agtgacgatt tttcatatat gacaggtcag
     4021 gtgcttgtgc ttgacggagg actcagctta tgatgaatct gcttgaaatc aatcagagaa
     4081 taaaacaaag accacccttt cagatgattg agagggtgac cgagcttgag ccgaatgttt
     4141 cggcaacagg tataaaaaat gtgtcggtga acgagccgta ttttgcaggt cattttcccg
     4201 acacaccgat tatgccggga gtattgctca ttgaatctgc ggcacagctt tgcagtcttg
     4261 tatttgctcc cgaaagcgtt gaggaggaca agctgtatgt tcttctcaag gttaaggatt
     4321 tcaaaatgct ccgccccgtt attccgggtg acacgcttat tatcagcgta aatgttacaa
     4381 tgtcaacaaa gtcggcattt gaatttgcgt gtgtcatcaa ggttgacggt gaagtgaggg
     4441 caaagggaaa tcttttgttt accacaatgg ataaaaatgc ggtttacaag ccgtcacagg
     4501 agtgattatg aaagttctcg tattaaacgg tagtccaaag ggcgaaaaaa gcaatactct
     4561 caacattaca aaagcatttc ttgacggctt ttcagccgat acggaagttg aatatatcac
     4621 ggttaaaaag gaaacaatca agccatgtat gggttgcttt tcgtgttgga gcagaacacc
     4681 cggcaaatgt gttataaagg acgatatgca gaaaatctac gaaaagatta attctgccga
     4741 tattatcatt gagagctttc cgctctactt tttcggtatg ccgtcacaga tgaaagcatt
     4801 aaccgacaga tgtctgccgt atatgctccc ctattcggga aatgttgtcg aggacaaaga
     4861 agcctctttc catgaactgc gtgatgaagc aatgcacgaa aagaggcttt tggttattac
     4921 aacttgcggc tatgtgagtg ccgaaccgat gtatcccgca cttataaaac agcttgattt
     4981 gatttgcggt aacggcaatt acacgatgat aaaatgcccc gagggcgagc tttttattgc
     5041 agaaaaagct gaaagacaga gaaaggcata ccttgattca atcacggagg caggcaggga
     5101 attctgcgaa aaccgctgtc tttgcgatga aacaatgaaa aaaatttcaa agcctattct
     5161 ctcccccaaa ggatttgagg ctattactaa ggctcattgg aaaatgagtt aatcagcttt
     5221 tcgggcgaac atattcggac aatgctccga gaacgaactc gttgacagcg tctgcaagct
     5281 tttcggagct ttctgcacag ccgtcattga accaacggac ataaaccgag atgaatcccg
     5341 aaacgacaaa ctcaacaagg tatttgagtt ttgtttcatt tttaaaatta agcacaggtc
     5401 ttattgaaac ctcgataaat cttttcaaaa gctcaacaga gcgtcccgag ccgaacacct
     5461 cgggagaatt tttcagaatt ttattaatct gttctttatt ttcaacaatg gaaagaccga
     5521 taaaattcag ctgattcaca agattgttgc cgtcacggtc ggattttttc gcatggctga
     5581 taacatcgtt gattatatcg tagttgatat catcgacaac atcctgaacc gtgttgtagt
     5641 gacggtaaaa ggttttgcgg ttaatcatcg ccttttctgc aagctcagtc accgtgattt
     5701 tggaaacatt tttttcggca agcaaatcaa tcagcgaatt ttttatattg gttcttgttt
     5761 ttacaatgcg aaggtcagtc acattagcgt ccatactatc accccataaa acagtttgat
     5821 tatagcacca aaaatttttt gagtcaacgg aggtccttat gacaggtctg ataattgaag
     5881 gcggagcaag gcgaggaatt tttaccgccg gtataaccga ctgtctgctt gaaaacaaaa
     5941 tacactttga ctatgttgca ggagtttcgg cgggagctga ggtcgccctt gattttaccg
     6001 caaaacagga aggtcgttcc cgcagggtta ttatgcccca cagaacaggc gatttttcgg
     6061 ttctcggttt tctttcaatg gatcttgaca atatgattta cagatttcct tatcaggact
     6121 atccgttcga ttttgataca ttttttgcgt cagatacaaa ctgcgaattt gtggcaaccg
     6181 actgcgtaac aggcaaggca aaatattttt ccgagaacaa aagcgaacag cgattgcttg
     6241 actccgtaag agcgtcctgc acagttccta ttctctatca gataagcgaa tttgagggcg
     6301 gaaagtatgt tgacggcagt attgccgatg ctgttccctt tgaccgtgcg tttgaacagg
     6361 gctgttcccg tgtgcttgtg cttttgacaa agcccgaaaa tgagccttgc acggactatc
     6421 gcaagtttga atttttaatc aacaaaaaat acaaggacta tccgaacctc atcaacgctc
     6481 ttatgacgag atttgaccgc tataatgagc aatgcaaaag aatgaaacag cttgaggagg
     6541 acggcatact tatggtactc cgcccgtcac acaagtatgt aaaatcattt gagatgaaca
     6601 cggatgtgct tgacgaggcg tataacgccg gcaagaatct tgcaaaagaa agacttgccg
     6661 aaattgaaga tttcctcaat gttctcgaaa agaaataatc aaaacaacaa gttacattaa
     6721 tatatcttcc caaaaagcaa ggtgcaattt cgtgccttgc tttcttttta tatgcaattt
     6781 caacaagtaa aaagtgttca atatgtgact tattccaatt aaataacaat agtattgtat
     6841 aatgtcaaaa aacatggtat attcagcata tattttaaaa cacggagatt tatatgaaaa
     6901 agcaactaat gatttttgac tttgtgtgtt ttggaatcgg agcaattttt ttgacttttg
     6961 tcgccatact tcaaaattgc ggtataaaca ttaccaatgg aagtgtaatc ggaattgtca
     7021 taacagtgct tttgtttact ctgatattac ttagcacagc taatgtactc ggctttgact
     7081 gtaccgtttc aaacataact tttttaagac caatattact gttcattgcg ttatacattt
     7141 tttattgcat gccgtttatg ggctttatcg gcaaggcggg aaatgtgtgg aacagtataa
     7201 tgttcgccca cttcggcatt acagtatcaa gacaattcta ctacatctcc aaatcaccca
     7261 tagccgaaaa atttgtaaaa tcaccttttg tctataccaa aggcactgaa tttttttcca
     7321 gtgcgggatc attctttaaa tttctttcag tcataatcat cccgatgacc gtaatcggaa
     7381 taatattaaa cataaccaca aacggaatca atgtggcaag catattttcc taacaaacac
     7441 ggagcagaaa ttaaaatctg ctccgttaat tttttatttc aaaaaacaat tcaattgaca
     7501 tccaaatcat tatgcagtat gattgtatta acagataaac ttggctttag gtcaagacct
     7561 tttagaatgt ttcggagtga ttttatgtac acaatcggtc aggtatctca gatgtgcggt
     7621 attcctgttt caaccctgcg ttactacgac aaagagggac tttttccgca tatggagagg
     7681 gtttcgggta tccgcagatt ttccgacaga gagcttgaaa cactccgcat aattgactgc
     7741 ctcaaaaaat cgggacttga aatcagggaa ataagaaaat ttatgcaatg gtgctccgag
     7801 ggcagttcgt cctatccgca aaggcgagag ctttttgaaa atcagaaaaa aaccgtagaa
     7861 aaggaaattg agcgtcttca aaagacgctt gatatgctcc gctttaagtg ctggtactac
     7921 gatactgcca ttgctgacgg caacgaggac agaatcaacg aaatgctccc gaacaatctt
     7981 cccgaggata ttcaaaagct gtatgaccat gcccacagcg atgacgaaga ttaattttga
     8041 taatttgtaa attcacagaa ttacgctctc caaacggagg gcgttttatt ttgtgctatt
     8101 ttattttgtt ccgaaatatt ttatgtagct ttcaatgttg cagttgattt cttcaaaaat
     8161 tttccgcacc ccgtcaattc ttaaattctc atgataaacc tttgctctgc cctctctgtc
     8221 aatttcaatc agcaaaacat tctcaccgtc aacctcagca taaacatcgc acgataactc
     8281 cggatatttc acctaaccac ctcggtaatt tatatgtaga caagaggttg tctgttgcaa
     8341 aacattgaac agaaaaaatt tttatgataa aatttcaata tactgtaaca aaacagcaat
     8401 tttcggattt aatatacggg aggtgacaaa gtgccatttg aagaatttta cagacaaaac
     8461 tttaaaacag tttacggatt tctgattaat ctctgtaaaa acagcgacct tgcagaggaa
     8521 ttgactgccg aaacttttct taaagcattt gaacattaca aaagctacaa caaaaagtac
     8581 aagccctcaa catggctttg tgccattgcc aaaaacgaat atttaaaata cctgcgtaag
     8641 caaaagaaaa ttgatggttt tgacaatgca gaaattgccg acatcagcaa tttagaagaa
     8701 aagctttcgg ataaagacac ggcattgcga atacataaat atctgcatat tcttgatgaa
     8761 ccgtatcgtg aggtctttat tttaaaagtt tttgcagagc tgtcatataa ggaaattgcc
     8821 gaaattttcg gcaaaaaaga aacatgggta cgagtcacct attaccgtgc aaaagtcaga
     8881 ttattggaaa ggcttggtga tgataatgaa taaaaactgc aacatagtgc gtgatttaat
     8941 tcctttgtat tccgataata ccgcaagtga tgaaagcagg aaatttattg aggagcattg
     9001 ccgtacttgc gataaatgca atcgtatttt atcactttca aaaaccgaaa ttgacaaaac
     9061 ggcacacctt gacgatgaaa ttaacagcgt atggaaaagt attgaaaagc agaacaaaaa
     9121 gaaaagaata attaaagttg caattgcggc tattttggtt actgttctta tccccttaat
     9181 tattatcggg gcaaattata tgtacggtgc tgacaacaca gatacagcga aaagcccata
     9241 tttcagcgat gaaatgctaa atgaatttga caagggatat tcacaatcgg accaaaaaca
     9301 gcttgaaccg cttttgaatg atataaaaaa tgttattgat ttcaacggtg aatatgaaac
     9361 cgccaaagga aaattcggag aacttgcgta ttattcatat gaccgtgttg agggcgatta
     9421 cacagtcaaa gctaaggttg aattgaactc cgcaaagctt tacacagaca ctggatatat
     9481 gtggattgaa tacacaaagg atttatacac agatgacgga actttttgga tgacaaccaa
     9541 acccgtaaaa tcacgaatta ccgtaatcaa taaagacggt gaatggacag cggtcaatat
     9601 tcagtcggaa cagtaaagct tgttttaaat acacagatgt gttatactcg ggttagaaac
     9661 tgaaagaggc agagttatgg taagagaaat tgtacatgat cctatgtttt tacagagaaa
     9721 gtcggaggac gcaacacagg cagatttgca gacggcacag gatttgcttg acacactcag
     9781 ggcaaatttt gaccgttgtg tgggcatggc ggctaacatg ataggcgttg caaaaaagat
     9841 aatcgcaatt aatgacaacg gaaaatatct tgttatgttc aatcccgaaa ttattagcaa
     9901 gttcggtgaa tttgaaaccg aggaaggctg tctttcgctt gacggcgaac gcaaaacagt
     9961 tcgttacaaa acgataaaag taaaatattt caacgaaaat ttcaagcaga taaaacgcag
    10021 ttttacagac tttaccgcac agattattca gcatgaaatt gaccattgca acgggattct
    10081 gatttaaagt taatacaaag ccttctctcc ccgacagtca cacggtacaa tgtgtggctg
    10141 tcgggttttg ttttgcacaa aagttttact gcaatttatt cattacaact aattttaccg
    10201 tcaatctgaa ccttttttgg attattgttt tgtaaaaatc gcacgaaatt gcatggcaga
    10261 ttattttgca attgcacttt gaattatatt gtgctataat attaatacaa tagaaacaca
    10321 gaaaaattgt aattaatcaa aaggcggtga ttttatgaaa gaaatcacaa aaaatcaagc
    10381 gacagcaatt tggcagattt tctttgtatt gtggcttact gtcggatcaa ttgtgtgttt
    10441 taatctcggt tgtatagaag attcgccgat atgcacacct atgtttgcaa taactccgct
    10501 ttatatcata gagttctatt ttgaccaccc ctacaccgta caggcaatta tgtttcaaaa
    10561 ctttgtgctg atattgatgc ctgcactgct ttggttttta acatacaaat cagtattcaa
    10621 aaacaaaaaa tccgcaaata caattattct tattcttatg attcccgaca ccgttttgtc
    10681 agcattttac ggcttatttt ttacaatagg atattttttc acatccaatc actattttct
    10741 attgttagc
//
