LOCUS       gnlProkkaJJEOIDNF_152   9437 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JJEOIDNF_152.
ACCESSION   gnlProkkaJJEOIDNF_152
VERSION     gnlProkkaJJEOIDNF_152
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 02:59:08
            Original ID  :: gnl|Prokka|JJEOIDNF_152
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9437
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9437
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[242:2441]"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      243..2441
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
     cand_cluster    1..9437
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /kind="single"
                     /product="HR-T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9437
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="HR-T2PKS"
                     /region_number="1"
                     /rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /tool="antismash"
     CDS             2..241
                     /NRPS_PKS="Domain: PP-binding (5-74). E-value: 1e-11.
                     Score: 37.1. Matches aSDomain:
                     nrpspksdomains_ctg152_1_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg152_1"
                     /sec_met_domain="PP-binding (E-value: 2.4e-12, bitscore:
                     37.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTIADQIKEMLVENLRIPENILTYDSELFGDEIGLDSIDSIEIV
                     AGIDTLFGIDMTGADREHFQSIRALTEYVESKQG"
     aSDomain        17..223
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg152_1_PP-binding.1"
                     /evalue="1.00E-11"
                     /label="ctg152_1_PP-binding.1"
                     /locus_tag="ctg152_1"
                     /protein_end="74"
                     /protein_start="5"
                     /score="37.1"
                     /tool="antismash"
                     /translation="DQIKEMLVENLRIPENILTYDSELFGDEIGLDSIDSIEIVAGIDT
                     LFGIDMTGADREHFQSIRALTEYV"
     CDS             243..2441
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (66-399). E-value:
                     2.7e-50. Score: 163.3. Matches aSDomain:
                     nrpspksdomains_ctg152_2_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: t2fas"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: hr-t2pks-ksa"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 80.1; E-value:
                     2.7e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg152_2"
                     /sec_met_domain="hr-t2pks-ksa (E-value: 2.9e-106, bitscore:
                     345.4, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="t2fas (E-value: 6.8e-23, bitscore: 70.8,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADKKRCVVTGLGLICGVGDNVKDCWDAVTLGHSGIDEVKSVDTS
                     NCYAHKGAEVDKASSELSPENYDRSSLLCIHAANEAFEDANIDASEKNIGVILGSCVGG
                     AASIDKYYTDEIKGDGGKKEDIFKMGASAIANNVSAHFGLEGITANIVNACAAGTMSIG
                     YACDLIREGKGDVFIAGGSDSFSSLAFSGFHALHALDKNACSPFNHSTGITLGEGSGIL
                     VIESYEHAVERGAKIYCEILGSGVSSDAYHITAPRPDGEGQMSAIRRAVESSALSFDDI
                     DYINAHGTGTAKNDEAEFLSLHTLFDGNDHLSVSSTKSMTGHCLGAAGSIEAVFSVKAI
                     KENLVPPTIGYSDEDLKMLSEKAGNIDFIPNKSHTKDVHYAMSNSFAFGGNNASIIFSD
                     NEHDIPDNSKNEKIYITGISKLTGTRTDEHSLNCNLTSEDYDKHGIKVAFYRKLDRFSQ
                     LQLLSGMDALADADIKIDKDNEYKTGIVIGTADGPMTEIVDFQKKAITRGTEKGSAFSF
                     PNTVYNAAGGYLSIFSGIKGYNATVANGNQAGLQSICYAADILADGNESVMLAAGTDEN
                     TKTNLELYTKAELLEKPLGEGSVTLVLETEESANGRNARKYAEIKGYAQAHRPVSYDNS
                     EVDSKAVVEVIEKACVNAGIEADNIDFVCCDDRKIIKTLMPCYDVSQEIGNARAAASAM
                     TAAYAAELLSDSEKNYEYGLALSMGAGGTYSAVILKKA"
     aSDomain        441..1439
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg152_2_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.70E-50"
                     /label="ctg152_2_PKS_KS.1"
                     /locus_tag="ctg152_2"
                     /protein_end="399"
                     /protein_start="66"
                     /score="163.3"
                     /tool="antismash"
                     /translation="YDRSSLLCIHAANEAFEDANIDASEKNIGVILGSCVGGAASIDKY
                     YTDEIKGDGGKKEDIFKMGASAIANNVSAHFGLEGITANIVNACAAGTMSIGYACDLIR
                     EGKGDVFIAGGSDSFSSLAFSGFHALHALDKNACSPFNHSTGITLGEGSGILVIESYEH
                     AVERGAKIYCEILGSGVSSDAYHITAPRPDGEGQMSAIRRAVESSALSFDDIDYINAHG
                     TGTAKNDEAEFLSLHTLFDGNDHLSVSSTKSMTGHCLGAAGSIEAVFSVKAIKENLVPP
                     TIGYSDEDLKMLSEKAGNIDFIPNKSHTKDVHYAMSNSFAFGGNNASIIFSD"
     CDS             2457..3191
                     /NRPS_PKS="Domain: PKS_KR (3-167). E-value: 2.7e-16. Score:
                     51.8. Matches aSDomain: nrpspksdomains_ctg152_3_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     226.8; E-value: 4.7e-69)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg152_3"
                     /sec_met_domain="adh_short (E-value: 3e-40, bitscore:
                     127.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 4e-35, bitscore:
                     111.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTALVTGSSRGIGKACALKLAELGYDIAVNCNSNLEMAQKAVD
                     EITSLGRKAVAYKANTADIDEVKDMFRNIQQDFGGIDVLVNNAGVVDDAYLLMIKDESL
                     ERSLDINIKGYFNCARQASLKMLRKKNGIIINISSVSSVLAVEGQSVYSATKGAVNAMT
                     HTLAKELAKYGIRVNAVAPGFIETEMMNGIPEELQKKYLEAIPEKRFGTVQDVANVVGQ
                     LCSDDFSYMTGQVLVLDGGLSL"
     aSDomain        2466..2957
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg152_3_PKS_KR.1"
                     /evalue="2.70E-16"
                     /label="ctg152_3_PKS_KR.1"
                     /locus_tag="ctg152_3"
                     /protein_end="167"
                     /protein_start="3"
                     /score="51.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGSSRGIGKACALKLAELGYDIAVNCNSNLEMAQKAVDEIT
                     SLGRKAVAYKANTADIDEVKDMFRNIQQDFGGIDVLVNNAGVVDDAYLLMIKDESLERS
                     LDINIKGYFNCARQASLKMLRKKNGIIINISSVSSVLAVEGQSVYSATKGAVNAMTHTL
                     A"
     CDS             3188..3643
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1270:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine
                     (Score: 92.9; E-value: 3.7e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg152_4"
                     /transl_table=11
                     /translation="MMNLLEINQRIKQRPPFQMIERVTELEPNVSATGIKNVSVNEPYF
                     AGHFPDTPIMPGVLLIESAAQLCSLVFAPESVEEDKLYVLLKVKDFKMLRPVIPGDTLI
                     ISVNVTMSTKSAFEFACVIKVDGEVRAKGNLLFTTMDKNAVYKPSQE"
     CDS             3646..4350
                     /locus_tag="ctg152_5"
                     /transl_table=11
                     /translation="MKVLVLNGSPKGEKSNTLNITKAFLDGFSADTEVEYITVKKETIK
                     PCMGCFSCWSRTPGKCVIKDDMQKIYEKINSADIIIESFPLYFFGMPSQMKALTDRCLP
                     YMLPYSGNVVEDKEASFHELRDEAMHEKRLLVITTCGYVSAEPMYPALIKQLDLICGNG
                     NYTMIKCPEGELFIAEKAERQRKAYLDSITEAGREFCENRCLCDETMKKISKPILSPKG
                     FEAITKAHWKMS"
     CDS             complement(4351..4920)
                     /locus_tag="ctg152_6"
                     /transl_table=11
                     /translation="MTDLRIVKTRTNIKNSLIDLLAEKNVSKITVTELAEKAMINRKTF
                     YRHYNTVQDVVDDINYDIINDVISHAKKSDRDGNNLVNQLNFIGLSIVENKEQINKILK
                     NSPEVFGSGRSVELLKRFIEVSIRPVLNFKNETKLKYLVEFVVSGFISVYVRWFNDGCA
                     ESSEKLADAVNEFVLGALSEYVRPKS"
     CDS             4997..5836
                     /locus_tag="ctg152_7"
                     /transl_table=11
                     /translation="MTGLIIEGGARRGIFTAGITDCLLENKIHFDYVAGVSAGAEVALD
                     FTAKQEGRSRRVIMPHRTGDFSVLGFLSMDLDNMIYRFPYQDYPFDFDTFFASDTNCEF
                     VATDCVTGKAKYFSENKSEQRLLDSVRASCTVPILYQISEFEGGKYVDGSIADAVPFDR
                     AFEQGCSRVLVLLTKPENEPCTDYRKFEFLINKKYKDYPNLINALMTRFDRYNEQCKRM
                     KQLEEDGILMVLRPSHKYVKSFEMNTDVLDEAYNAGKNLAKERLAEIEDFLNVLEKK"
     CDS             6032..6571
                     /locus_tag="ctg152_8"
                     /transl_table=11
                     /translation="MKKQLMIFDFVCFGIGAIFLTFVAILQNCGINITNGSVIGIVITV
                     LLFTLILLSTANVLGFDCTVSNITFLRPILLFIALYIFYCMPFMGFIGKAGNVWNSIMF
                     AHFGITVSRQFYYISKSPIAEKFVKSPFVYTKGTEFFSSAGSFFKFLSVIIIPMTVIGI
                     ILNITTNGINVASIFS"
     CDS             6723..7172
                     /gene_functions="regulatory (smcogs)
                     SMCOG1171:transcriptional regulator, MerR family (Score:
                     81.8; E-value: 1.4e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg152_9"
                     /transl_table=11
                     /translation="MYTIGQVSQMCGIPVSTLRYYDKEGLFPHMERVSGIRRFSDRELE
                     TLRIIDCLKKSGLEIREIRKFMQWCSEGSSSYPQRRELFENQKKTVEKEIERLQKTLDM
                     LRFKCWYYDTAIADGNEDRINEMLPNNLPEDIQKLYDHAHSDDED"
     CDS             complement(7239..7430)
                     /locus_tag="ctg152_10"
                     /transl_table=11
                     /translation="MKYPELSCDVYAEVDGENVLLIEIDREGRAKVYHENLRIDGVRKI
                     FEEINCNIESYIKYFGTK"
     CDS             7569..8051
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 86.4;
                     E-value: 3.1e-26)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg152_11"
                     /transl_table=11
                     /translation="MPFEEFYRQNFKTVYGFLINLCKNSDLAEELTAETFLKAFEHYKS
                     YNKKYKPSTWLCAIAKNEYLKYLRKQKKIDGFDNAEIADISNLEEKLSDKDTALRIHKY
                     LHILDEPYREVFILKVFAELSYKEIAEIFGKKETWVRVTYYRAKVRLLERLGDDNE"
     CDS             8005..8754
                     /locus_tag="ctg152_12"
                     /transl_table=11
                     /translation="MQKSDYWKGLVMIMNKNCNIVRDLIPLYSDNTASDESRKFIEEHC
                     RTCDKCNRILSLSKTEIDKTAHLDDEINSVWKSIEKQNKKKRIIKVAIAAILVTVLIPL
                     IIIGANYMYGADNTDTAKSPYFSDEMLNEFDKGYSQSDQKQLEPLLNDIKNVIDFNGEY
                     ETAKGKFGELAYYSYDRVEGDYTVKAKVELNSAKLYTDTGYMWIEYTKDLYTDDGTFWM
                     TTKPVKSRITVINKDGEWTAVNIQSEQ"
     CDS             8815..9225
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275:peptide deformylase (Score: 127.2; E-value:
                     6.8e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg152_13"
                     /transl_table=11
                     /translation="MVREIVHDPMFLQRKSEDATQADLQTAQDLLDTLRANFDRCVGMA
                     ANMIGVAKKIIAINDNGKYLVMFNPEIISKFGEFETEEGCLSLDGERKTVRYKTIKVKY
                     FNENFKQIKRSFTDFTAQIIQHEIDHCNGILI"
ORIGIN
        1 gaacaatact attgcagatc agattaagga aatgctcgta gaaaacctta gaattcccga
       61 aaacattctt acatacgatt cagagctttt cggtgacgaa atcggtcttg actcaatcga
      121 ctcaatcgaa atcgttgcag gcatcgacac acttttcggt attgatatga caggtgcaga
      181 ccgtgagcac ttccaatcaa tcagagcact tacagaatat gtagaaagca agcagggtta
      241 atatggctga caaaaagaga tgtgttgtca caggactcgg acttatctgc ggcgtcggtg
      301 acaatgtaaa ggattgctgg gatgccgtaa cactcggtca ctccggcatt gatgaggtta
      361 agtcggttga cacctcaaac tgttatgcac acaagggtgc agaggttgac aaggcatcgt
      421 cagagctttc tcccgaaaac tatgaccgtt cttcccttct ctgtattcat gccgcaaacg
      481 aggcttttga agatgcaaac attgacgcat ccgaaaagaa catcggtgtt attcttggca
      541 gttgtgtagg cggtgcggca agcattgaca aatattacac agacgaaatt aagggtgacg
      601 gcggtaaaaa agaagatatt ttcaaaatgg gtgcttcagc aattgccaac aatgtttccg
      661 ctcatttcgg acttgagggc attaccgcaa acatagtcaa cgcttgtgcg gcaggcacaa
      721 tgagcatcgg ctatgcctgt gaccttatcc gtgagggcaa gggtgatgtg ttcattgcag
      781 gcggttcgga cagcttttct tcacttgcat tcagcggttt ccacgctctc catgcgcttg
      841 acaaaaacgc ctgttccccg ttcaatcaca gcacaggtat cacgctcggc gagggttcgg
      901 gtattcttgt aatcgaaagc tacgaacacg ctgttgaacg aggtgcaaag atttactgtg
      961 aaattctcgg ttcgggtgta agcagtgacg cttaccacat taccgctccc cgtcccgacg
     1021 gcgaaggtca gatgagtgca atcagaaggg ctgttgaaag ctctgctctt agttttgacg
     1081 atattgacta cataaacgca cacggaacag gtactgccaa aaatgacgag gctgaatttc
     1141 tttcacttca cacacttttt gacggcaatg accacctttc tgtcagctca acaaaatcta
     1201 tgacaggtca ttgtctcggt gcggccggct caattgaggc tgtattttcc gtaaaagcaa
     1261 taaaagaaaa cctcgttccc cctacaatcg gctactccga tgaggatttg aagatgcttt
     1321 ccgaaaaggc gggcaacatt gactttattc cgaacaagag ccatacaaaa gatgttcact
     1381 atgcaatgtc aaactcattt gcattcggcg gcaacaacgc aagcatcatt ttctcggaca
     1441 acgagcatga tattcccgac aacagtaaaa atgaaaaaat ttacattacg ggcatttcaa
     1501 agcttacagg cacaaggact gacgaacaca gccttaactg caatcttacc tccgaggatt
     1561 atgacaaaca cggaatcaag gttgcatttt acagaaagct tgaccgtttc agccagctcc
     1621 agcttttgag cggtatggac gcacttgcag acgctgacat aaaaattgac aaagacaacg
     1681 aatataaaac aggtattgta atcggcacgg ctgacggccc tatgaccgaa attgttgatt
     1741 tccagaaaaa ggcaatcaca agaggtactg aaaagggcag tgctttttca ttcccgaata
     1801 cggtttacaa tgccgcaggc ggttatctaa gcattttctc aggcatcaag ggctacaacg
     1861 caactgttgc aaacggcaat caggcaggac tgcagagtat ttgctatgcc gctgatattc
     1921 ttgcagacgg caacgaaagc gttatgcttg ccgcaggtac cgatgaaaat acaaagacaa
     1981 accttgaact ctatacaaag gccgaattgc ttgaaaaacc gctcggtgag ggctctgtaa
     2041 ctctcgttct tgaaacagag gaaagtgcaa acggcagaaa tgcacgcaag tatgcagaaa
     2101 ttaagggtta tgcacaggct caccgccctg tatcgtacga caactcagag gttgacagca
     2161 aggctgttgt tgaggttatc gaaaaggctt gtgtgaatgc cggcattgag gcagacaata
     2221 tcgactttgt atgctgtgac gacaggaaga ttatcaagac acttatgccc tgctatgatg
     2281 tatcgcagga aatcggcaat gcaagagccg cagcaagtgc aatgacagcg gcatatgcgg
     2341 ctgagcttct ttctgacagc gaaaaaaatt acgaatacgg acttgctctt tcaatgggtg
     2401 cgggcggaac atactctgcc gtaatcctga agaaagcgta aaaatcggag gtaaatatga
     2461 gcaaaaccgc tcttgtaaca ggttcatcaa ggggcattgg caaggcttgc gctttaaagc
     2521 ttgcagagct tggatatgac attgccgtga actgcaattc aaatttagaa atggctcaaa
     2581 aggctgttga cgaaattaca tcactcggca gaaaagccgt tgcctacaag gcgaacacgg
     2641 cagatattga cgaagtaaag gatatgttcc gcaatattca gcaggacttt ggcggaattg
     2701 atgtgcttgt caacaacgca ggtgtggttg acgacgctta ccttttgatg attaaggacg
     2761 agtcgcttga aagaagtctt gacattaata tcaaaggata tttcaattgt gcaagacagg
     2821 catcgcttaa aatgctccgc aaaaagaacg gaatcatcat caacatttct tccgtaagct
     2881 ctgttcttgc agttgaaggt cagtcggttt acagtgcaac aaagggtgcg gtaaacgcta
     2941 tgacacacac gcttgcaaag gaacttgcaa agtacggaat cagagtaaac gcagttgcgc
     3001 ccggttttat cgaaaccgaa atgatgaacg gcattcccga agaattgcaa aaaaagtatc
     3061 ttgaggctat tcccgaaaag agattcggca cagttcagga tgtcgcaaat gtagtcggac
     3121 agctttgcag tgacgatttt tcatatatga caggtcaggt gcttgtgctt gacggaggac
     3181 tcagcttatg atgaatctgc ttgaaatcaa tcagagaata aaacaaagac caccctttca
     3241 gatgattgag agggtgaccg agcttgagcc gaatgtttcg gcaacaggta taaaaaatgt
     3301 gtcggtgaac gagccgtatt ttgcaggtca ttttcccgac acaccgatta tgccgggagt
     3361 attgctcatt gaatctgcgg cacagctttg cagtcttgta tttgctcccg aaagcgttga
     3421 ggaggacaag ctgtatgttc ttctcaaggt taaggatttc aaaatgctcc gccccgttat
     3481 tccgggtgac acgcttatta tcagcgtaaa tgttacaatg tcaacaaagt cggcatttga
     3541 atttgcgtgt gtcatcaagg ttgacggtga agtgagggca aagggaaatc ttttgtttac
     3601 cacaatggat aaaaatgcgg tttacaagcc gtcacaggag tgattatgaa agttctcgta
     3661 ttaaacggta gtccaaaggg cgaaaaaagc aatactctca acattacaaa agcatttctt
     3721 gacggctttt cagccgatac ggaagttgaa tatatcacgg ttaaaaagga aacaatcaag
     3781 ccatgtatgg gttgcttttc gtgttggagc agaacacccg gcaaatgtgt tataaaggac
     3841 gatatgcaga aaatctacga aaagattaat tctgccgata ttatcattga gagctttccg
     3901 ctctactttt tcggtatgcc gtcacagatg aaagcattaa ccgacagatg tctgccgtat
     3961 atgctcccct attcgggaaa tgttgtcgag gacaaagaag cctctttcca tgaactgcgt
     4021 gatgaagcaa tgcacgaaaa gaggcttttg gttattacaa cttgcggcta tgtgagtgcc
     4081 gaaccgatgt atcccgcact tataaaacag cttgatttga tttgcggtaa cggcaattac
     4141 acgatgataa aatgccccga gggcgagctt tttattgcag aaaaagctga aagacagaga
     4201 aaggcatacc ttgattcaat cacggaggca ggcagggaat tctgcgaaaa ccgctgtctt
     4261 tgcgatgaaa caatgaaaaa aatttcaaag cctattctct cccccaaagg atttgaggct
     4321 attactaagg ctcattggaa aatgagttaa tcagcttttc gggcgaacat attcggacaa
     4381 tgctccgaga acgaactcgt tgacagcgtc tgcaagcttt tcggagcttt ctgcacagcc
     4441 gtcattgaac caacggacat aaaccgagat gaatcccgaa acgacaaact caacaaggta
     4501 tttgagtttt gtttcatttt taaaattaag cacaggtctt attgaaacct cgataaatct
     4561 tttcaaaagc tcaacagagc gtcccgagcc gaacacctcg ggagaatttt tcagaatttt
     4621 attaatctgt tctttatttt caacaatgga aagaccgata aaattcagct gattcacaag
     4681 attgttgccg tcacggtcgg attttttcgc atggctgata acatcgttga ttatatcgta
     4741 gttgatatca tcgacaacat cctgaaccgt gttgtagtga cggtaaaagg ttttgcggtt
     4801 aatcatcgcc ttttctgcaa gctcagtcac cgtgattttg gaaacatttt tttcggcaag
     4861 caaatcaatc agcgaatttt ttatattggt tcttgttttt acaatgcgaa ggtcagtcac
     4921 attagcgtcc atactatcac cccataaaac agtttgatta tagcaccaaa aattttttga
     4981 gtcaacggag gtccttatga caggtctgat aattgaaggc ggagcaaggc gaggaatttt
     5041 taccgccggt ataaccgact gtctgcttga aaacaaaata cactttgact atgttgcagg
     5101 agtttcggcg ggagctgagg tcgcccttga ttttaccgca aaacaggaag gtcgttcccg
     5161 cagggttatt atgccccaca gaacaggcga tttttcggtt ctcggttttc tttcaatgga
     5221 tcttgacaat atgatttaca gatttcctta tcaggactat ccgttcgatt ttgatacatt
     5281 ttttgcgtca gatacaaact gcgaatttgt ggcaaccgac tgcgtaacag gcaaggcaaa
     5341 atatttttcc gagaacaaaa gcgaacagcg attgcttgac tccgtaagag cgtcctgcac
     5401 agttcctatt ctctatcaga taagcgaatt tgagggcgga aagtatgttg acggcagtat
     5461 tgccgatgct gttccctttg accgtgcgtt tgaacagggc tgttcccgtg tgcttgtgct
     5521 tttgacaaag cccgaaaatg agccttgcac ggactatcgc aagtttgaat ttttaatcaa
     5581 caaaaaatac aaggactatc cgaacctcat caacgctctt atgacgagat ttgaccgcta
     5641 taatgagcaa tgcaaaagaa tgaaacagct tgaggaggac ggcatactta tggtactccg
     5701 cccgtcacac aagtatgtaa aatcatttga gatgaacacg gatgtgcttg acgaggcgta
     5761 taacgccggc aagaatcttg caaaagaaag acttgccgaa attgaagatt tcctcaatgt
     5821 tctcgaaaag aaataatcaa aacaacaagt tacattaata tatcttccca aaaagcaagg
     5881 tgcaatttcg tgccttgctt tctttttata tgcaatttca acaagtaaaa agtgttcaat
     5941 atgtgactta ttccaattaa ataacaatag tattgtataa tgtcaaaaaa catggtatat
     6001 tcagcatata ttttaaaaca cggagattta tatgaaaaag caactaatga tttttgactt
     6061 tgtgtgtttt ggaatcggag caattttttt gacttttgtc gccatacttc aaaattgcgg
     6121 tataaacatt accaatggaa gtgtaatcgg aattgtcata acagtgcttt tgtttactct
     6181 gatattactt agcacagcta atgtactcgg ctttgactgt accgtttcaa acataacttt
     6241 tttaagacca atattactgt tcattgcgtt atacattttt tattgcatgc cgtttatggg
     6301 ctttatcggc aaggcgggaa atgtgtggaa cagtataatg ttcgcccact tcggcattac
     6361 agtatcaaga caattctact acatctccaa atcacccata gccgaaaaat ttgtaaaatc
     6421 accttttgtc tataccaaag gcactgaatt tttttccagt gcgggatcat tctttaaatt
     6481 tctttcagtc ataatcatcc cgatgaccgt aatcggaata atattaaaca taaccacaaa
     6541 cggaatcaat gtggcaagca tattttccta acaaacacgg agcagaaatt aaaatctgct
     6601 ccgttaattt tttatttcaa aaaacaattc aattgacatc caaatcatta tgcagtatga
     6661 ttgtattaac agataaactt ggctttaggt caagaccttt tagaatgttt cggagtgatt
     6721 ttatgtacac aatcggtcag gtatctcaga tgtgcggtat tcctgtttca accctgcgtt
     6781 actacgacaa agagggactt tttccgcata tggagagggt ttcgggtatc cgcagatttt
     6841 ccgacagaga gcttgaaaca ctccgcataa ttgactgcct caaaaaatcg ggacttgaaa
     6901 tcagggaaat aagaaaattt atgcaatggt gctccgaggg cagttcgtcc tatccgcaaa
     6961 ggcgagagct ttttgaaaat cagaaaaaaa ccgtagaaaa ggaaattgag cgtcttcaaa
     7021 agacgcttga tatgctccgc tttaagtgct ggtactacga tactgccatt gctgacggca
     7081 acgaggacag aatcaacgaa atgctcccga acaatcttcc cgaggatatt caaaagctgt
     7141 atgaccatgc ccacagcgat gacgaagatt aattttgata atttgtaaat tcacagaatt
     7201 acgctctcca aacggagggc gttttatttt gtgctatttt attttgttcc gaaatatttt
     7261 atgtagcttt caatgttgca gttgatttct tcaaaaattt tccgcacccc gtcaattctt
     7321 aaattctcat gataaacctt tgctctgccc tctctgtcaa tttcaatcag caaaacattc
     7381 tcaccgtcaa cctcagcata aacatcgcac gataactccg gatatttcac ctaaccacct
     7441 cggtaattta tatgtagaca agaggttgtc tgttgcaaaa cattgaacag aaaaaatttt
     7501 tatgataaaa tttcaatata ctgtaacaaa acagcaattt tcggatttaa tatacgggag
     7561 gtgacaaagt gccatttgaa gaattttaca gacaaaactt taaaacagtt tacggatttc
     7621 tgattaatct ctgtaaaaac agcgaccttg cagaggaatt gactgccgaa acttttctta
     7681 aagcatttga acattacaaa agctacaaca aaaagtacaa gccctcaaca tggctttgtg
     7741 ccattgccaa aaacgaatat ttaaaatacc tgcgtaagca aaagaaaatt gatggttttg
     7801 acaatgcaga aattgccgac atcagcaatt tagaagaaaa gctttcggat aaagacacgg
     7861 cattgcgaat acataaatat ctgcatattc ttgatgaacc gtatcgtgag gtctttattt
     7921 taaaagtttt tgcagagctg tcatataagg aaattgccga aattttcggc aaaaaagaaa
     7981 catgggtacg agtcacctat taccgtgcaa aagtcagatt attggaaagg cttggtgatg
     8041 ataatgaata aaaactgcaa catagtgcgt gatttaattc ctttgtattc cgataatacc
     8101 gcaagtgatg aaagcaggaa atttattgag gagcattgcc gtacttgcga taaatgcaat
     8161 cgtattttat cactttcaaa aaccgaaatt gacaaaacgg cacaccttga cgatgaaatt
     8221 aacagcgtat ggaaaagtat tgaaaagcag aacaaaaaga aaagaataat taaagttgca
     8281 attgcggcta ttttggttac tgttcttatc cccttaatta ttatcggggc aaattatatg
     8341 tacggtgctg acaacacaga tacagcgaaa agcccatatt tcagcgatga aatgctaaat
     8401 gaatttgaca agggatattc acaatcggac caaaaacagc ttgaaccgct tttgaatgat
     8461 ataaaaaatg ttattgattt caacggtgaa tatgaaaccg ccaaaggaaa attcggagaa
     8521 cttgcgtatt attcatatga ccgtgttgag ggcgattaca cagtcaaagc taaggttgaa
     8581 ttgaactccg caaagcttta cacagacact ggatatatgt ggattgaata cacaaaggat
     8641 ttatacacag atgacggaac tttttggatg acaaccaaac ccgtaaaatc acgaattacc
     8701 gtaatcaata aagacggtga atggacagcg gtcaatattc agtcggaaca gtaaagcttg
     8761 ttttaaatac acagatgtgt tatactcggg ttagaaactg aaagaggcag agttatggta
     8821 agagaaattg tacatgatcc tatgttttta cagagaaagt cggaggacgc aacacaggca
     8881 gatttgcaga cggcacagga tttgcttgac acactcaggg caaattttga ccgttgtgtg
     8941 ggcatggcgg ctaacatgat aggcgttgca aaaaagataa tcgcaattaa tgacaacgga
     9001 aaatatcttg ttatgttcaa tcccgaaatt attagcaagt tcggtgaatt tgaaaccgag
     9061 gaaggctgtc tttcgcttga cggcgaacgc aaaacagttc gttacaaaac gataaaagta
     9121 aaatatttca acgaaaattt caagcagata aaacgcagtt ttacagactt taccgcacag
     9181 attattcagc atgaaattga ccattgcaac gggattctga tttaaagtta atacaaagcc
     9241 ttctctcccc gacagtcaca cggtacaatg tgtggctgtc gggttttgtt ttgcacaaaa
     9301 gttttactgc aatttattca ttacaactaa ttttaccgtc aatctgaacc ttttttggat
     9361 tattgttttg taaaaatcgc acgaaattgc atggcagatt attttgcaat tgcactttga
     9421 attatattgt gctataa
//
