LOCUS       c00104_gnlPro..         8337 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JJEOIDNF_104.
ACCESSION   c00104_gnlPro..
VERSION     c00104_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 22:03:19
            Original ID  :: gnl|Prokka|JJEOIDNF_104
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8337
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8337
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[77:4324]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      78..4324
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..8337
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..8337
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             78..2981
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_1"
                     /sec_met_domain="HGD-D (E-value: 2.4e-18, bitscore: 55.6,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 2.6e-39, bitscore:
                     123.9, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKLGLDIGSTTIKCVVLDDENKLIYSTYERHYSRITEKIAEILAL
                     VRTRIDGVENASVALSGSAGMGVAESVGVDFIQEVYATRVAANTFIPGTDVIIELGGED
                     AKILFLTNGLEVRMNGTCAGGTGAFIDQMATLLNVKLEDMDELAKQHEKTYTIASRCGV
                     FAKTDIQPLLNQGARKSDIAESIFNAVVSQTVAGLAQGREIEGQIVYLGGPLTFMSELR
                     NCFDRTLGTKGICPENSLYYVACGAALCAEKTIDFDEVIEKVKNYRGSGNFAFNQPLFK
                     NEEEYRKFCDRHAKADVKQKELKGYTGKAYIGMDAGSTTVKGVVLNDDGELLYSKYLPS
                     KGNPVEIMKQFLDEVYEINPEINVVSSAVTGYGEDIVKNAFAVDYGIVETIAHFTAAKY
                     FMPDVEFIIDIGGQDIKCFKIHNGAIDNIFLNEACSSGCGSFLQTFANALGYEIADFAK
                     LGLFAKRPVDLGSRCTVFMNSSVKQAQKDGATIEDISAGLSLSVVKNALYKVIRASSPD
                     ELGKRVVVQGGTFLNDAVLRAFEQEMGVEVVRPNIAGLMGAYGAALYAKKKSKGVGKST
                     ITDKKGLDEFVHEIKVANCGMCNNNCRLTINSFGKGRKFIAGNRCERPITKKAPANDMN
                     MYAYKLNLIDSYKPVEGIRGKLGIPMALNMYELYPFWYRFFTELKFEVFHSPYSTRKLY
                     QRGQQTIPSDTVCFPAKLVHGHIQTLIDMGAETIFYPCLSYNFDEHLGDNHYNCPVVAY
                     YPEVIKNNMKDIRKVHFIKEYFGIHRPNDFPKKAYERLSFHFPDLTLNEVRNAAKLAYQ
                     EQENYRKKVIDKGSEIIAKAEKEGKKIFVLAGRPYHIDPEINHGIDRLISGFDVAIVSE
                     DVISPRVEHFRTHVLNQWTYHARLYAAAKYVTTRKDMELVQLVSFGCGVDAITTDEVRE
                     ILESKNKIYTQIKIDEITNLGAVKIRIRSLLAALEND"
     CDS             2981..4324
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_2"
                     /sec_met_domain="HGD-D (E-value: 6.5e-28, bitscore: 87.0,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGNSVMAELKYDKKTGRLLFTKQMKKEYTILMPNMAPIHFKILE
                     KVFNYYGYKSDLLDTTGPEIAQTGLKYVHNDTCYPALLVIGQFINALQSGKYDVHKVAL
                     MITQTGGGCRASNYIFLLRKALKKAGFEFVPVISLSFGMEHNSGFSLTLPLIRRFVGGL
                     VYGDQLMLLSNQTKPYEVNKGESMALVDEWTDKISDMLIQGKGYTLEEIDETLDKITKS
                     FTKIELNKVPKVKVGIVGEIYVKYSKMANNGLEDFLADQDCEVCIPGLMGFASFKVDNR
                     IEDYKMFGGSRVKYKFCSMLLNYLTKLEGLMVDAAEKYGFVPPHRYAHTKELVNGVIGY
                     GSKMGEGWLLTAEMIELADTGYENIVCTQPFGCLPNHINGKGAIRKIKEIRPNANIVTI
                     DYDPGAPKVNQENRIKLMLAVGKEELKKKLEAEKNGEKAESSEKSEKK"
     CDS             4468..5265
                     /locus_tag="ctg104_3"
                     /transl_table=11
                     /translation="MKKRLKGFFQRLARWLNVREMRQHRVKAGVYIIIRLILVSLLTAG
                     ILNGKWENVMTCVLTLGLLMLPLFIDRKLSVALPSVLETIVVLFVFAANVMGELGAFYE
                     KIPIWDSLLHTVNGFICAGVGFGLTDILNRSERVKLSLSPIFVCLFSFCFSMTVGVVWE
                     FFEFGADMLFEKDMQKDTVITAIHSGLISGKPNVIMHIRDITSTVVNGENLGINGYLDI
                     GLIDTMKDLLVNFVGAAVFDTIGWFYLKGRSAGFLRNFIPRKK"
     CDS             complement(5504..7243)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trypsin_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1057:Trypsin-like peptidase (Score: 122; E-value:
                     1.3e-37)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg104_4"
                     /sec_met_domain="Trypsin_2 (E-value: 1.2e-38, bitscore:
                     122.0, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNFDNNNMGGFEPQKPFTEKPVQNNNMNTEQTIPVSEPETQEEQ
                     AQNVQPQNGNTPYGDYIFGNNNQNTANNASPTENVPPYQQNQNPNPNTYAQPWQYGYGQ
                     YPYSGQNPQYNQNNQQYGQYQNNTGYNQNVPPYQQNMYGQPPYGNNGTYNQQYNPQMFA
                     QYPQKKTKGGIIALIIVLCSLLTIGFIGMMVYGFSVDIKEDLNNDRSDSGNSFRLPNKD
                     STTPFETLPDTSSQGKTHNESDYSDKVNKDYSGMKLESNPKDAKTNNGYTAAKASEKVS
                     DSVVGILCYSDDVPDQADTTTASSQGSGIIFSQDGYVITNAHVIGNSKTAYAIRVVTSD
                     GKVYKAGVVGYDSRTDIAVLKMDDAKGLTPATFGDSSQLEVGQDIIVVGNPGGLDYQNT
                     TTKGVISALDRKLSTSSLTKYIQTDAAINPGNSGGPLVNYYGQVVGITTSKIVSETYEG
                     MGFAIPSQTVKSIVDTLVKNGYVEGRVKIGISGIAVTSDQASNYNIPQGIYVQSIVSGG
                     PCDGTSLKEGDIITEVDGETITSFADVYAILETHKPGDKIKVKYYSSSSGDGEVEITLQ
                     EDK"
     CDS             complement(7230..7406)
                     /locus_tag="ctg104_5"
                     /transl_table=11
                     /translation="MIIFFVNYPVGTDDIRHYEIFVHFGNLLAKNFVSLLKDKRSLYPT
                     VTNKCRSNFYGQF"
     CDS             complement(7403..8335)
                     /locus_tag="ctg104_6"
                     /transl_table=11
                     /translation="GERRTLMNVGFIDYYLDEWHAHHYPQLLQQKSYGILKVAYAYGKI
                     DSPITGKTSKQWCQEFGVQHCETIEEVVEKSDVLIVLSPDNCEMHEELCEKPLMSGKRT
                     YVDKTFAPDQKTAKAIFEVAEAHNTPCYSTSALRFASEYEALKGKKIQAAAFWGPYDLE
                     TYSIHQLEPMIMLMQGNVKRVLAQQSGDWTQICLEWSDGRAASLTCKGKDGAFWANIDL
                     EQENRAFQITWDNFGAFIENLVSVLEGEDIPVTHLETVRMMAVREACLKASRQPGIWNH
                     LKRAYCKRSYMQSGSELPDRSSRYLAGVV"
ORIGIN
        1 attttcttgg caaaaaatac tataattaac tagatatgca caatgagatt actatgtatt
       61 gatttcggag gcacaagttg aaattaggat tggatattgg ctcaacaaca ataaaatgtg
      121 ttgtgcttga cgacgaaaac aaattaatat acagcacata tgaaaggcat tattcccgaa
      181 ttacggaaaa gattgcagaa attcttgcac ttgtacggac aaggattgac ggcgttgaaa
      241 atgcctcggt ggctctttcg ggttctgccg gaatgggtgt tgccgagtct gtcggcgttg
      301 attttattca ggaggtttac gcaacaagag ttgccgccaa tacttttatt ccgggtacag
      361 atgttataat tgaactcggc ggtgaggatg caaagatatt gtttctcaca aacggacttg
      421 aggtaagaat gaacggtacc tgcgccggcg gcacgggtgc gtttattgac cagatggcaa
      481 cacttctgaa tgttaagctt gaggatatgg acgagcttgc aaaacagcac gaaaagacat
      541 acacaatcgc atcaagatgc ggtgtgtttg caaagaccga tattcagccg ctccttaatc
      601 agggtgcgag gaagagcgac atcgcagaga gtattttcaa tgcggttgta agccagactg
      661 ttgcaggtct tgcacagggc agagaaattg aaggtcagat tgtatatctc ggcggacctc
      721 ttacatttat gagcgaactg cgaaactgct ttgaccgcac gctcggaaca aagggcatct
      781 gccccgaaaa ttcactttat tatgttgcct gcggtgcggc tttgtgtgcc gaaaagacta
      841 ttgattttga cgaggttatc gaaaaggtaa agaactaccg tggcagcggt aactttgcgt
      901 tcaatcagcc cctctttaaa aacgaagagg agtacagaaa attctgcgac cgtcatgcaa
      961 aggctgatgt taagcagaag gagctaaagg gttacaccgg caaggcttat ataggaatgg
     1021 acgcaggttc aacaaccgta aagggtgttg ttctcaatga tgacggtgag ttgctctatt
     1081 caaaatatct gccatcaaag ggaaaccccg ttgagattat gaagcaattc cttgacgagg
     1141 tttacgaaat aaatcccgaa ataaatgttg tttcttctgc cgtaacaggt tacggtgagg
     1201 acattgtaaa gaacgcattt gcggttgatt acggcattgt tgaaacaatc gcccacttta
     1261 ccgccgcaaa atactttatg cccgatgttg aatttatcat cgatatcggc ggacaggata
     1321 tcaaatgctt taagatacat aacggtgcaa ttgacaatat attccttaat gaggcttgtt
     1381 catcgggttg cggaagcttt ttgcagactt ttgcaaacgc tctcggatat gagattgccg
     1441 actttgcaaa gctcggactt tttgcaaagc gtcccgttga cctcggctca cgctgtaccg
     1501 tattcatgaa ttcaagcgtt aagcaggctc agaaagacgg cgcaacaatt gaagatatct
     1561 cggcaggtct ttcactcagc gttgtaaaga atgcccttta caaggttatt cgtgcgtcaa
     1621 gccccgacga actcggcaag cgtgttgtgg ttcagggcgg tactttcctt aacgatgctg
     1681 ttttgcgtgc atttgaacag gaaatgggcg ttgaagttgt ccgtcctaac attgcaggac
     1741 ttatgggtgc ttacggtgcg gctctttacg caaagaaaaa gtcaaagggc gttggcaaga
     1801 gtacaattac cgacaaaaag ggacttgatg aatttgttca cgaaatcaag gttgcaaact
     1861 gcggtatgtg caacaacaac tgccgtctta caataaattc attcggcaag ggcagaaagt
     1921 ttattgcagg aaaccgttgt gaaagaccga tcacaaagaa agctcctgca aacgatatga
     1981 atatgtatgc ctataagctg aatctcattg attcctacaa gcctgttgaa ggcataagag
     2041 gtaagcttgg aattcctatg gcgctcaata tgtatgagct ttatccgttc tggtacagat
     2101 tctttacaga acttaaattt gaggtgttcc actcaccgta ttcaacaaga aagctttatc
     2161 agagaggtca gcagacaatt ccgagcgata ccgtttgctt ccctgcaaag cttgttcacg
     2221 gtcacattca gactcttatt gatatgggtg cagaaacaat tttctacccc tgtctttcct
     2281 ataattttga cgagcatctc ggagataacc attacaactg tcctgttgtt gcttactatc
     2341 ccgaggttat caaaaacaat atgaaggata tacgcaaggt tcacttcata aaggaatact
     2401 ttggtattca ccgcccgaac gattttccga agaaagccta tgaaagactt tcgttccact
     2461 tccccgacct cactcttaac gaggtaagaa atgcggctaa gcttgcatat caggaacagg
     2521 aaaattacag aaaaaaggtt atcgacaagg gcagcgagat tattgccaag gctgaaaaag
     2581 agggcaaaaa gatttttgtt cttgcaggca gaccatatca tattgatccc gaaattaacc
     2641 acggaatcga cagacttatc tcaggctttg atgttgcaat cgtcagcgaa gatgttattt
     2701 ctccgagagt tgaacatttc cggactcatg ttctcaacca gtggacatac cacgcaagac
     2761 tttatgcggc ggcaaaatat gttacaacaa gaaaggacat ggagcttgtt cagcttgtat
     2821 ccttcggctg cggtgttgat gcgattacaa ccgatgaggt aagagaaatt cttgaaagca
     2881 aaaataagat ttacactcag attaagatag atgaaattac aaacctcgga gcagttaaaa
     2941 tccgaatccg cagtttgctt gctgcgcttg aaaacgattg atgaaaggaa attctgttat
     3001 ggcagagttg aagtatgaca aaaaaacagg tcgtttgctg tttacaaagc agatgaaaaa
     3061 ggaatataca attcttatgc ccaatatggc gcctattcat tttaaaatac ttgaaaaggt
     3121 gttcaactac tacggctata agtctgattt gctcgacaca acaggtccgg agattgcgca
     3181 gacaggtctt aaatatgttc acaacgatac ctgttatccg gctttgctgg ttataggtca
     3241 gttcatcaat gctctgcaaa gcggaaaata tgatgttcac aaggttgccc tgatgattac
     3301 tcagacaggc ggcggatgtc gtgcgtcaaa ctacattttc cttttgagaa aggctctcaa
     3361 aaaggcaggc tttgagttcg ttcccgtaat ttcgctttca ttcggtatgg agcacaacag
     3421 cggtttttcg ctcacacttc cgcttatccg cagatttgtc ggcggtcttg tgtacggcga
     3481 ccagttaatg ctgctttcaa accagacaaa gccctatgag gtgaacaagg gtgaaagtat
     3541 ggcgcttgtt gatgagtgga cggataagat ttccgatatg ctcatacagg gcaagggcta
     3601 cacgcttgaa gaaattgacg aaacccttga taaaattaca aagtcattca caaaaattga
     3661 gcttaacaaa gtgccgaagg ttaaagtcgg tattgtcggc gaaatctatg taaaatactc
     3721 caaaatggct aacaacggtc ttgaggactt tcttgcagat caggattgcg aggtttgcat
     3781 ccccggactt atgggttttg cgtcgtttaa ggttgataac cgtattgagg attataagat
     3841 gttcggcggc agcagagtaa agtacaagtt ctgttcgatg cttcttaact acctcacaaa
     3901 gcttgaggga cttatggttg atgcggctga aaagtacggc ttcgttccgc ctcacagata
     3961 tgctcacaca aaggagcttg taaacggtgt tatcggctac ggcagtaaga tgggcgaggg
     4021 ttggttgctg acagccgaga tgattgaact tgccgataca ggctatgaga atatcgtatg
     4081 cacacagcct ttcggttgtc tgccgaatca tatcaacggt aagggcgcaa tcagaaagat
     4141 taaagaaatc agaccgaatg ccaatatcgt taccatcgac tatgatccgg gtgcgccgaa
     4201 ggtaaatcag gagaaccgta tcaagctgat gcttgctgtc ggcaaagagg aactcaagaa
     4261 aaagcttgag gctgaaaaaa atggcgaaaa agccgaatcg tcagagaagt cagagaaaaa
     4321 gtaatttaat atcaatgctt atgagtcatc gcagatggcg gtggcttttt tattttgcgg
     4381 taatatcagg cagaaaaagc taatacaatt ttacaggggt ttatctcgtt tttaaggaaa
     4441 aaataagtgt aaaaatcggg ggatattatg aaaaaacgac ttaaaggatt ttttcaaagg
     4501 cttgcacggt ggctgaatgt gcgtgaaatg cgacagcaca gagttaaggc aggcgtttac
     4561 atcattataa ggctcatact tgtgtcactt ttgactgccg gcattttaaa cggaaaatgg
     4621 gagaatgtca tgacctgcgt gttaacgctc ggactgttga tgcttccgtt gttcatcgac
     4681 cgaaagctgt cggtagcgtt gccgagtgtg cttgaaacga ttgttgtgct gttcgtgttt
     4741 gcggcaaatg ttatgggtga gctcggtgcg ttctacgaaa agattccgat atgggattca
     4801 ttgctccata ctgtgaacgg ctttatctgt gcaggcgttg gttttggatt gaccgatatt
     4861 ttgaacagaa gcgaacgggt gaaattgagc ctctcgccca tattcgtgtg cctgttttcg
     4921 ttctgctttt caatgacagt cggtgttgtg tgggagtttt ttgagtttgg tgcggatatg
     4981 ctttttgaaa aggatatgca aaaggacacc gtaatcacgg caatacattc gggtttgatt
     5041 tcgggcaagc cgaatgtgat aatgcacatc agggatataa catcaaccgt tgtgaacggt
     5101 gaaaatctcg gtattaacgg ttaccttgac atcggtctga tcgatacaat gaaagatttg
     5161 cttgttaatt ttgtaggagc ggcagttttt gacaccatag gttggtttta cctgaaagga
     5221 agaagtgcag gttttttgcg gaattttatc ccaaggaaga agtagcggcg atcagtgatc
     5281 gccaatcggt ttggttgtaa aaccaaaccg aacaaaccgc aagtcaattt tgtggtatta
     5341 ttatctgtta aagcaatcat ataatgtcga accaatttta caattggttc gattggcggt
     5401 caatgaccgc cgctacggga atgcacatta ttttcagaca aacaaaaggc agtcacattg
     5461 ccgtgactgc cctcttgctt ttggtgatat tcttatatta aaattactta tcttcctgaa
     5521 gtgtgatttc aacctcaccg tcgcccgatg atgagctgta atatttaacc ttgattttgt
     5581 cccccggctt gtgggtttca agaatcgcat aaacatctgc aaagcttgta attgtttcgc
     5641 cgtcaacctc tgtgatgata tcgccttctt taaggcttgt gccgtcacac ggaccgcccg
     5701 atacgatact ctgaacataa atgccctgcg gaatgttgta atttgatgcc tgatcggagg
     5761 ttactgcaat gcccgaaatg ccgattttta ctctgccttc aacatagccg ttctttacaa
     5821 gtgtgtcaac aatgcttttt actgtctgtg acggaattgc aaagcccata ccttcgtaag
     5881 tttcggaaac aatctttgaa gttgtaattc cgacaacctg accgtagtag tttacaagcg
     5941 gaccgcccga gttgcccgga ttgattgcgg catcggtctg aatgtacttt gtaaggcttg
     6001 atgttgaaag ttttctgtca agcgccgaaa taacgccctt ggttgttgtg ttctgatagt
     6061 caagaccgcc ggggttgccg actacgataa tatcctgacc aacctcaagc tgtgacgaat
     6121 caccgaatgt tgcaggagta agtccctttg catcgtccat tttgagaacc gcaatatcgg
     6181 ttcttgaatc gtaacctaca acacctgcct tgtatacctt gccgtcagat gttacaactc
     6241 tgattgcata ggctgttttg ctgttgccga ttacatgagc gtttgtgata acatagccgt
     6301 cctgtgagaa gataattccg cttccctgtg aagatgcggt tgttgtgtca gcctgatcgg
     6361 gtacatcgtc cgagtaacag agaatgccga ctaccgagtc ggaaaccttt tctgacgctt
     6421 ttgcggctgt gtagccgttg tttgtttttg cgtctttcgg attgctttca agcttcatac
     6481 ccgagtaatc cttgttcact ttgtcactgt agtcagactc attatgagtt ttaccctgcg
     6541 aagatgtgtc gggaagggtt tcaaacggtg ttgtgctgtc tttattcgga agtctgaacg
     6601 aattgcccga atcacttcgg tcgttgttca aatcttcttt tatgtcaacc gaaaatccgt
     6661 acaccatcat gccgataaaa ccgattgtaa gaagtgaaca gagaacgata atcaacgcaa
     6721 ttattccgcc ctttgttttc ttttgtgggt actgtgcgaa catctgcgga ttgtattgct
     6781 gattgtatgt accgttgttg ccgtagggag gctgtccgta catattctgc tgatacggag
     6841 gtacattctg attgtatcct gtgttgtttt gatactgtcc gtactgctga ttgttctgat
     6901 tatactgcgg attctgtccg ctgtagggat actgaccgta accgtactgc cacggctgag
     6961 cgtaggtgtt cggattcgga ttttgattct gctgatacgg cggaacattt tcagtcggac
     7021 ttgcattgtt tgccgtgttt tggttgttgt tgccgaaaat ataatcaccg tacggtgtgt
     7081 tgccgttctg cggctgaaca ttctgagcct gttcttcctg tgtttcgggt tcggaaacgg
     7141 gaattgtctg ttccgtgttc atattattgt tttgtacggg cttttcggtg aacggctttt
     7201 gcggttcaaa cccacccata ttgttgttgt caaaattgtc cataaaagtt actcctacat
     7261 ttatttgtta ccgtggggta caaactgcgt ttgtccttaa gtaatgaaac aaaatttttt
     7321 gcaagcaaat tgccgaaatg aacaaatatt tcgtagtggc ggatatcatc tgtccctacg
     7381 ggatagttta caaaaaatat tatcatacaa cacccgccaa ataccgggag cttctgtcag
     7441 gcagttcaga cccgctctgc atgtagcttc ttttgcagta tgctcttttt aggtggttcc
     7501 agatccccgg ctggcgggag gctttcagac aggcttcccg gactgccatc atcctgaccg
     7561 tctccaaatg cgtcacagga atgtcttccc cttccaaaac ggaaaccaga ttctctataa
     7621 atgcgccaaa gttatcccat gtgatctgaa aggcacggtt ttcctgctcc agatcaatat
     7681 ttgcccagaa ggcaccgtcc tttcctttac aggtcaggga tgcagctctt ccatccgacc
     7741 attccaaaca gatctgtgtc cagtcacctg actgttgcgc aagcacacgt tttacgtttc
     7801 cctgcatcag catgatcatc ggttccagct gatgaatgct gtaggtttcc agatcatagg
     7861 gtccccaaaa tgcagctgcc tggattttct ttcctttcag tgcttcatat tccgaggcaa
     7921 accgaagtgc cgatgtggaa tagcaaggtg tgttatgagc ttctgcaact tcaaaaattg
     7981 ctttcgctgt tttttgatcc ggagcaaagg tcttgtccac ataggttctc ttgccggaca
     8041 tgagcggttt ttcgcacaat tcttcatgca tctcacaatt atccggcgac agtacgatca
     8101 gcacatcact tttttccaca acctcttcaa tggtttcaca atgctgtacg ccaaattcct
     8161 ggcaccattg tttgcttgtt tttcctgtga tgggactgtc aatctttcca tatgcatacg
     8221 caacctttaa tatgccatag cttttttgct gcagcagctg cggataatga tgtgcatgcc
     8281 attcatccag ataataatct ataaacccta cgttcatcaa agttctcctt tcacccc
//
