LOCUS       c00151_gnlPro..         5893 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JJEOIDNF_151.
ACCESSION   c00151_gnlPro..
VERSION     c00151_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 22:03:19
            Original ID  :: gnl|Prokka|JJEOIDNF_151
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5893
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5893
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2332:5560]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2333..5560
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5893
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5893
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             189..2027
                     /locus_tag="ctg151_1"
                     /transl_table=11
                     /translation="MKKFLPIVMAAVMSMSAIAVSAVSANAVEPLNTPVQYAQVARASL
                     ATPKISKAESVYGGVKLTWNKVNGAAKYRVYYKGRKGWTRMVDTTSTSYIDKDVSSGRN
                     YTYTVRCISADGKSFTSGYDSKGTSVKYVAAPEISKLENVNGGVKISWGKVSGATKYRV
                     YYKGSKGWTRMVDTTSTSYIDKDVSSGRNYTYTVRCITSDAKKFTSGYNPTGKSVKYVA
                     TPKISKLEVTYDGVKLTWNKVAGAEKYRVYYKDRNGWTKLADTTGTTMLDMNVVSKEFD
                     LSIDDIYYTVRCISKDAKSFTSGYDSKGTPIGDHQDCPEIYSIGAVNNGVEMHWTGDAP
                     KFRVYIKENGSWKKIAETYDNYYVHKGARSGSNTYTVRGVSKDGKKFTTMFNPTGVTYR
                     YKTSDKTRDAYINYMMNHTDEWMPSLGSDHNLSGVMFLDFDFDGVPELVAQKADSNEYS
                     FHSVVYKFEDGKLKRVGNVNDGFAIYYNKTAKKYEVHDLKISLNVDDGYYWSGNSIITY
                     DGENLFANMYSARGVGEESNNKVYYRYFDGNDKNISRAKYNEINLKQFNNCVNAHMFTQ
                     FIATGYGDASVWGENTTAENKQSLLDAYNSFSYEKY"
     CDS             complement(2333..3373)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg151_2"
                     /sec_met_domain="IlvN (E-value: 3e-84, bitscore: 269.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.4e-61, bitscore: 194.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLK
                     DSGCDVIIGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKLAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(3434..3925)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg151_3"
                     /sec_met_domain="ALS_ss_C (E-value: 6.8e-31, bitscore:
                     94.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQDPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             complement(3938..5560)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg151_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-43, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             complement(5758..5892)
                     /locus_tag="ctg151_5"
                     /transl_table=11
                     /translation="YTIGGISRIGKDNLMIMMSPDNADKKSDLNPRIYFTKLSDLNFQ"
ORIGIN
        1 ctataaaagc cgttctcatt tttgagagcg gttttttgtt attttaaata ttttgaaata
       61 taaaataaat gaaaaagtgt attgaaaagt attgtttttt taacaattta atgttacaat
      121 taacttgcat aaaaaaataa acgaattatt ttgtaatgcg tagaatttga acaaagtgag
      181 ggatagatat gaaaaagttt ttacctatag tcatggcggc ggtaatgtcg atgtctgcga
      241 ttgcggtttc ggcagtttct gcaaatgcgg ttgaaccgct taacacaccc gtgcagtatg
      301 cacaggttgc aagggcaagc ttagcaactc cgaaaatttc aaaagccgaa agtgtttacg
      361 gcggtgtaaa gcttacatgg aacaaagtga acggtgcggc taaatacaga gtttactaca
      421 agggtcgtaa aggttggaca cgaatggtcg atacaacttc aacatcatat atcgacaagg
      481 atgtttcatc gggcaggaat tacacctata ctgtaagatg tatttctgct gacggaaaga
      541 gctttacaag cggttatgat tcaaagggga caagcgtaaa atatgttgct gctcccgaaa
      601 tttcaaagct tgaaaatgta aacggcggtg ttaaaatctc atggggcaaa gtaagcggtg
      661 cgactaaata cagagtttac tacaagggca gtaaaggctg gacacgaatg gtcgatacaa
      721 cttcaacctc atatatcgac aaggatgttt catccggcag aaattacact tatactgtaa
      781 gatgtatcac atcagacgca aagaaattta caagcggtta taacccgaca ggcaagtcgg
      841 taaagtatgt tgccacaccg aaaatttcaa aacttgaggt tacatatgac ggcgttaagc
      901 tgacatggaa caaggtagca ggtgcagaaa aatatcgtgt gtactacaag gacagaaacg
      961 gttggacaaa acttgccgat acaacaggca cgactatgct tgatatgaat gttgtttcaa
     1021 aggaatttga tttaagcatt gatgatattt attacacggt tcgttgtatc agcaaggatg
     1081 ccaagagttt tacaagcggc tacgattcaa agggtacgcc cattggcgat catcaggatt
     1141 gtcccgaaat ttacagcatt ggtgcagtaa acaacggtgt tgaaatgcat tggacgggag
     1201 atgcaccaaa gttccgtgtt tatattaaag aaaacggctc ttggaagaag atagcagaaa
     1261 cttatgacaa ctattatgtt cacaagggtg caaggtccgg cagtaacact tatacggtaa
     1321 gaggtgtttc aaaagacggt aaaaagttta ctacgatgtt taacccaacc ggtgtaacat
     1381 acagatataa gacatccgat aaaacaaggg acgcttatat caattatatg atgaatcaca
     1441 ccgatgaatg gatgccaagc ctgggaagtg atcacaattt gtcaggtgtt atgtttttgg
     1501 atttcgactt tgacggagtt ccggagcttg ttgcacaaaa ggctgattcc aatgagtata
     1561 gtttccattc cgttgtttac aaatttgaag acggtaagtt aaaaagagtg ggaaatgtta
     1621 acgacggttt tgcgatatac tataataaaa ctgccaaaaa gtatgaggtt cacgacctaa
     1681 agatatcttt aaatgtagat gacggttact attggtcggg taattcaata atcacatacg
     1741 acggagagaa tctttttgca aatatgtatt cggcaagagg cgtaggcgaa gaatcaaata
     1801 ataaggttta ttatagatat tttgacggta atgacaaaaa tatttcacgg gcaaaatata
     1861 acgagattaa ccttaaacag tttaataatt gcgtgaatgc acatatgttt acccaattta
     1921 ttgcgacagg ttatggtgat gccagcgtat ggggtgagaa cactaccgct gagaataagc
     1981 agtctttgct tgacgcatat aattctttct cctatgagaa gtattgatta tttaaaaatt
     2041 gatatgtttt aactgcaaaa gggttcagcc gtaaaaagct gaaccctttt attgcacaac
     2101 aaaaaacggt tcagccaaat tgactgaacc gttaatctgt actatgtaac gcttggaaac
     2161 aagtagttgt aaattatcac aaactaccta cacgaactgc gggcgaggta ctcgcaaaaa
     2221 gggtagcttg aaaaaattca agctacccca aatttataac tatgttaagc tcgggtgaca
     2281 gaagtttgaa tacatcaaac tgtcttcacg aactgtgtgc gagacactcg cattagttgt
     2341 tgatgagctt atcttcgtca gaccagctgt agagctttct aacttcctta ccgaatactt
     2401 cggcaggagc ttcggcagca agctttctca tagccttaaa gtgaacctgt gaaccggcat
     2461 cgctcatgtc aaggaggaag tccttagcaa atgtaccgtc ctgaatgtca gaaagaacct
     2521 ttctcatagc cttcttagta tcctctgtga tgatctttgg acctgtgatg tagtcaccgt
     2581 actcagctgt gttagagatt gaatatctca tgcctgcaaa acctgactga tagataaggt
     2641 caacgatgag cttcatctca tggatacact caaagtaagc gtttcttggg tcgtaaccgg
     2701 catcgcaaag tgtttcaaaa cctgcctgca taagtgcgca aacaccgccg caaagaacag
     2761 cctgttcacc gaagaggtct gtttctgttt ctgttctgaa tgttgtttca agaacgccgg
     2821 ctcttgcacc gccgataccg agtgcatatg caagtgcgag atccttagcc tgacctgtag
     2881 catcctgctc aacagcaacg aggcaaggta cacccttacc aacctgatac tctgaacgaa
     2941 ctgtgtgacc aggtccctta ggagctacca ttgtaacatc aacatccttt ggaggcttga
     3001 tgcaaccgaa gtgaatgtta aagccgtgag cgaacataag catattgcct gcttcgaggt
     3061 ttggctcgat gtcgttcttg taaagagctg cctgcttttc atcgttgata agaatcatga
     3121 tgatgtcagc ctgctttgca gcctctgctg atgtatatac cttaaagccc tgtgcctcag
     3181 cctttgccca gctcttgctg cctttgtaaa gaccgatgat tacatcgcaa cctgaatcct
     3241 tgaggttgag agcgtgtgca tgaccctggc tgccgtaacc gataatagca attttcttac
     3301 ccttgagaag gtcaaggttg caatctgact gatagtagat tggtgctgtc atgttttttg
     3361 tgtagtcttt catattaaag tcctccttac cgcaaacgcg gcatataaat taaaatatat
     3421 gctaactgta agattaaacg gaaaccgaag ctgtgcctct gtcaatggca acagtacctg
     3481 ttcttacaat ctcacggata ccataaggct tgagtaagtc aacaagcgtg ttgatgcggc
     3541 ttgcacattc gcagtactca acggtaactg acgaagggga tacatcaacg attttcgcct
     3601 gcataatttc aaccgttttg acaatttcgg ctctttttga ggcggcgcag tgaaccttga
     3661 ttaaaacaag ctcacggctg ataaattcgc cctcgttaag cctttttacc ttaataacgg
     3721 gaatgagctt gttgagctgt ttttcaagct gttcaacaat gtactcgtca ccgtttgcaa
     3781 cgattgtgat tcgggaaacc gacgggtcct gagtaacacc tactgcaagt gagtcgatgt
     3841 taaaacctcg gcgagagaaa agtcccgaaa tttttgaaag aacgcccgcc tgattttcaa
     3901 caagtattga taatgtatac tgcattttat cacctcatta aattgacgga gtgtcggggt
     3961 gaacatcgca aacaagaatg aacggttttt ccgaatcaac aatacccttg atgatgtttt
     4021 cagcttcctt gtttgaatga gcctctgcat ggtcaatgcc gtaagcatcg gcaatcttca
     4081 agaagtcggg atcaccgttg agaattgttg cggagtgtct gccgccgtag tgcttgtcct
     4141 gaagttcacg aaccattccg agtcgtgcgt ttttcataat gatgatttta attccgagct
     4201 gattgcctgc aatagtcgca agctcattaa gccccatctg aaaactgccg tcaccgcaga
     4261 ttacaataac atcacggtcg ggtcttgcaa actttgcacc gattgcagcg ggaattgagt
     4321 aacccattgt acccataccg cctgttgtga ggaatctgcc ctcacgaata cggaagttgt
     4381 ttgcacacca gatttgattt tgtcctacat cggcaacaag aattgccttt gagcggaaca
     4441 ttgcactgag atgaccgaca agtgttctcg gctcaacaaa gccgtcaaat acgggaggct
     4501 cacggtaaag gtcttttttc cagttcttta cggtttcgct ccacattgtt gtaaccttgt
     4561 aatcgccgat gctgtcaagc agcatattga tgacattttt catatcgcct acaatcggaa
     4621 tttctgtttt aacattctta ccgatttcag cagggtcaat gtcaatgtga attacctttg
     4681 tgttttcact catctggtcg ggagccgcaa cagctctgtc accgagtctt gcaccgcata
     4741 cgattacaag gtcggcttcg tgaagagcac ggttggcaac agccttgccg tgagtgccga
     4801 gcattccgag ataaagctca tgctcgctgg gcataacacc gatgcccatc atagttgaaa
     4861 taacggggat acccgtagtt tctgcaaatt tttgaagttt aagcttgata cccgaactca
     4921 gcacgccgcc gcctgatacg ataacaggac gcttgcttgc gttgatggcc tcaacagcct
     4981 ttttaacctg aattgcgtgt cccttagtgt tcggcttgta accgataatg tttacgcttt
     5041 cgggatattc aaaactttca atttcatttt cctgaatatc aacgggaatg tcgataagta
     5101 caggaccggg tctgccggtt gaggcaatat ggaaagcctc tttgaaaact ctcggaaggt
     5161 cttctgtttt gctgacgaga taactgtgct ttacaaacgg ttcacaagct cccgtgatgt
     5221 cagcttcctg aaagacatct ctgccgagaa ggtcggaacg aacctgacct gtaatggcaa
     5281 caatcggaat agagtccgta taggcggttg caatgcctgt gatgaggttg gttgcaccgg
     5341 gaccggaagt tgccacgcaa acaccgggac gattactgca tcttgcatag ccgcttgccg
     5401 catgagcagc gttctgttcc tgacgaacaa gaatgtgggt aatgctcgaa tcgtaaactt
     5461 tatcgtaaaa tgggcagata gccgcaccgg gataaccaaa gactatgtca acgccctcgg
     5521 cttccaaaca ttttaccata atttcagcac cgctgatcat tatgttttgt ccctcctatc
     5581 cttatttatt gtgagcaaaa ggtgttttgt aacaataaat ataccttttt gctttaccgc
     5641 taattataca ataaatacct taaaaagtaa agagcagtat tgcccataaa ttaaattttt
     5701 tgcaggattt tgacagataa tttgcaaaat ggattttaat tgatttttac cgcctgttta
     5761 ctgaaaattt aagtcgctta gttttgtaaa gtatattctt ggattaaggt cacttttttt
     5821 gtctgcatta tcaggggaca tcattatcat caaattatct tttcctatcc gtgatatacc
     5881 gcctatagtg tac
//
