LOCUS       gnlProkkaHPCHFIGG_8    22694 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HPCHFIGG_8.
ACCESSION   gnlProkkaHPCHFIGG_8
VERSION     gnlProkkaHPCHFIGG_8
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 02:59:56
            Original ID  :: gnl|Prokka|HPCHFIGG_8
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 2145
            Orig. end    :: 24839
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22694
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12694]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12694
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..22694
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22694
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             590..1558
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 214.8; E-value: 3.4e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_5"
                     /transl_table=11
                     /translation="MKLGILGAGGIASTMAKTVAGMKDVEAYAVAARDLERARVFAQKY
                     EVKKAYGSYEEMLADDEVGLVYIATPHSHHYLHAKMCLEAGKHVLCEKAFTVNAEQAQK
                     LFDLAKEKKLLITEAIWTRYMPSRKMINDIIESGVIGEVTAVTANLSYTVSHVERIRKP
                     ELAGGALLDVGVYPINFASMVLGDKVKDVKATAIFQNGVDILDSIAMVFEGDRMATLQC
                     GAREISDRMGSIFGTRGYMQVQNINNPEKITVFDTEHKEVASYVVPEQISGYEYEVESC
                     MKAIHEGKTECPEMPHAETIRIMKIMDDIRKSWNYEIPCIE"
     CDS             1753..4434
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MKSNYKIFTAVFLSAIMTAAAPLTVCGAEVFSAGESFSDGTGSIP
                     AILTDMVLPDGEIGTEYQVQLEADTDVNWSLEEGSELPAGFTLSSGGVISGMPQEEGSF
                     SFTVQADNGIGVSSQELSLYVAQREQEPVIKQYELTSGTALIDLGIHAEGEQSRKRLFL
                     YNAGTDSLHLSDFPQSRYFDFSYAPIFDTNTDEEMQPGSCAAVDIDDKKNLPAGNYEET
                     VTFETKEGASCKVTLKVIVGASSEKDYELSIETGTEEEFTESDFYDPEFRVEKYVVVRN
                     SGKKETRIRIDTSGLKNFEVDDQMAKWTEDYEEQDSKKLLKPGETLYFYILPKQEYGIY
                     DETFAFLADDGSRYPLHVTMNREKNPTEKKQLEITEKSAGGFPTMQWGYKTLPEAKTYI
                     LKNVTDTDMKLSFNRSKECSVLLSGNAYLAPGESTELRLWPKLGLSVGKYSFQVTVTAK
                     TVAGEHLTTQNLYNSFIVGDRTYQGLADAVAPVTGITNGAEKTADALHLPKSLEVYGAE
                     VNGEKTTFSASVKWDVENCAYDPKSKAAQSFLVNGSLELNEDENNEGLDTAVQIMVQVD
                     AYQTLNRPVIDTRWTRVITNYAMLYLRDLSNEADGYQFVTAKSQKDLKKGNYTAQTKIT
                     NSELNQYPELKYIPEGTHSLYCRAYKENSSHVMEYGEWSDGVPVTVKAKTPDAPVVQKV
                     QVKKNDVRIVLNSKGEEPDGYDVVAARSKNGKEPSDYIKVKSGYSGSSKELILRGVPAG
                     TWYIGVHAYKYLNGSNTKVLSKWAEVRKVTVKTSLVTGKPAVKSAKVSRQGTKRNVAVT
                     FTVPKSCDGTDWVLAKKVSKSDNGSYTGVSSYAYTKKNQTKTTVVFKNVKPGVYYLAGR
                     AYVKGYAKSYTKWSKIKKIVVK"
     CDS             4674..5432
                     /locus_tag="ctg8_7"
                     /transl_table=11
                     /translation="MKQKKIAIIMAGILAAAAAMTGCAEQNKTETQVDYTQNSQEKSEQ
                     TKQKTAEKSQPDKKQVNKSTSIGKEDSNQTADKKTKISASSNNAGDVQNSENGTDSTAG
                     TDTDDSQTTGVDTSASEDNGSTGNGGTQSDQRADQAMIYDSEGNGRLISEADDGNWYDS
                     DGNYYGSWEDIEDAMVNENGVTDQDGNKYYWTAPHDASEEVTDPYDLYSWDPGTNSYIP
                     FQAAESDCSPVGRGNGWYYYDEDSGEYVPW"
     CDS             complement(5578..6471)
                     /locus_tag="ctg8_8"
                     /transl_table=11
                     /translation="MTKTEKAVTWAIRIANDPAHGYDQDNRWGPDYDCSSLVISAWQQA
                     GVPVKTKGATYTGNMKSVFLSCGFKDVTSKVNLSTGSGMKRGDVLLNIASHTVMHIGNG
                     QVVSASKNENNGYHGGKPGDQSGKEIKLQSYYNFPWDCVLRYTEDSSTTDPDPEPQPTA
                     GNAKIRKGQGYANKFANAGISITGKRDAATKKAGVKVLQTALNRDYGAGLDVDGIWGTN
                     TDNALGQHYVKNGETQYMVTAAEILLLLRAYDPNGVEIPGTFGSGLLSAVKAFQKAQGL
                     TVSGTCDRNTFLKLIS"
     CDS             complement(6659..6994)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 60.6; E-value: 4e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg8_9"
                     /transl_table=11
                     /translation="MKNNTIGKRIAEARINRNITQEHLEELSGLSVSTISRIETGKYMP
                     TIENLLKLSEILDVGLDYFLYDLLPHNKDIQSPAIQDAISIMNQMGERQTEYIVKILKI
                     YQASHQD"
     CDS             7113..7667
                     /locus_tag="ctg8_10"
                     /transl_table=11
                     /translation="MDEYTKDLYTMMFSLQTLQNQGITIRETVYKSLDKLLLWNKESEN
                     SKYLELALLHMQAYANMGFALDEENKTIREILKKTGKTREDFFPKGYLLGKRIKLTKSQ
                     VRGMIGRWRPSRDSPMTIGELVDDIIRKVKNHEEGRYIYQYHRTDVTTKGDIEVYELVI
                     NKDESYFYDVKKFRFYTFMEE"
     CDS             7673..8380
                     /locus_tag="ctg8_11"
                     /transl_table=11
                     /translation="MIRIMILDDDEMYLKKEKDITEQYFAEKNVDCTVTIYQNVEWFLL
                     GLNEEKFDMYILDIRMPGENGIEAAREIRRLYPDPVIIFITNFVDYAIEAYEVNTYRYI
                     PKECLKEKLPQAYDALLPGIMEKEERYYIINKRNEVEKLAYSDIFYMKKEGKYVIFVHR
                     RGEVKIRASLSTVEKELNSKEFIISDRGYLANIQHVMKMKGRDLYMRDGNIITVGRERF
                     KGVREAILNYWGV"
     CDS             8384..9865
                     /locus_tag="ctg8_12"
                     /transl_table=11
                     /translation="MLKVLLYGLATFMETGIGVWIFSQTFSERRILEKKYYVLEWLLYS
                     LIFFGIYNFSVSLWQIDKKIEKYVIKVICIYIIGLIAGIIYDIFFVKKKEMVLRRILYI
                     GMIFWLTAQYWAGYQSLLMIILGSGIIVLYVFCYFDCTFKQAYVWNFFYAVNIGLIKEA
                     YVVYAGVFNHKQWDDFYSYPRGHTYQEVIFWILGCLFIFWIIKFILSVNSIKGILRTRL
                     KELFIIGLLEYVLLIVSIIYKFGTIKKENFVMTACLLAVSNIALIGVYVKFQKKTLEMR
                     NQILDMRCKLMEEEYEELRMSYDRYRCLVHDEKHLLLYIKECLENGELDSCITFLNHYK
                     RESIRYSGVAWTGIPEINFMLNIKVRKMEEKNIFFKVDSKIEKIPMKDIDFVVLLGNLL
                     DNAIEAAEKCEEGKGKITCIFRNINDMFIFKVKNTSIYKPYEKNTKFYTSKKEKDEHGW
                     GIESVKQIVRKYNGEIDFKYDKDFFEVEIIISDNT"
     CDS             9882..10010
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_13"
                     /transl_table=11
                     /translation="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYGTIVCC"
     CDS_motif       9882..9992
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /locus_tag="ctg8_13_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9993..10010
                     /prepeptide="core"
                     /locus_tag="ctg8_13_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="519.7"
                     /monoisotopic_mass="519.2"
                     /core_sequence="TIVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /leader_location="[9881:9992](+)"
     CDS             10001..12694
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     762.3; E-value: 1.3e-230)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_14"
                     /sec_met_domain="DUF4135 (E-value: 3.4e-92, bitscore:
                     304.9, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.6e-51, bitscore:
                     168.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLKLDYLCRKNRTMFLKILILDVHRQKNFGNLKGSTPKEQYDYY
                     EKKYLNNATYVKSLLQEYPELKRLLELKNNSIQRAECEIRKSLYAEKEQIQKIFCDGRK
                     FSGTVGIYMSKGDTHRGGRSVAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGIS
                     CRTVQYLSHDSYGWEEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAH
                     GEYPVIIDMETYPGYLKQQSEKDGSSVEEKINKSTEIKLANSVIHTGMLPVLTWGRGNS
                     RVLISAMGTEEKIKTPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYT
                     ECIIRGFCRAYMVTMADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSRE
                     CRKALLNVIHKEGESSFMKEIHDYEIDSLLEMDIPCFEIDANSRSVYDGNGGEHKEYLP
                     CTPYESWRMHMKQMSYSDMECQCDYIRLSMEMLKASDGKKKMFPTRIKGYDTDKERKIY
                     SQIRKIVHRICSRAIIREQSAGWAGLQFWDNGHWNLRSGGIYLYDGISGIVLFLAKYLH
                     DFEEKNASAEEIYHLAVLRLKAYTDEIHKKQIYDKNLLTGIVNGESSVVYTYLYLFKLT
                     GKRVWMIYAEKHFSIIERVWKEDSQLDYLSGNAGAIVVAVMLYKETGNLKYYEIAADME
                     KDLWKKGQETGNGYGWRLKGTDGPLAGMSHGNSGFLMAYAALYECNHKAEYADKIQLLL
                     RYEDSLYSEKAGNWKDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLN
                     AADSLFYGEQDEKICLCHGMSGNLLIMKKYLRKYGNKKMKEQYEALCDCLLFQLDHPAK
                     ISGTEYLNLAFMNGISGTGMALMEIL"
     CDS             complement(12747..13271)
                     /locus_tag="ctg8_15"
                     /transl_table=11
                     /translation="MKTLTELIQNYQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDS
                     TQELYLTLLKTLPYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSL
                     QAPDSFDDTYYDVTAYINSYPSDSVQRKILSMYFYQDKSDAQIARKLKLSRQYVNRMKK
                     KLILRYISENK"
     CDS             13572..13802
                     /locus_tag="ctg8_16"
                     /transl_table=11
                     /translation="METTVMNVAVSQGIWAVLAVFLLIYIVKSNEQRDTKQEEREKNYQ
                     TVIESLTEKFQILNQVQSDLKEIKDNLFNKN"
     CDS             14405..16114
                     /locus_tag="ctg8_17"
                     /transl_table=11
                     /translation="MYLKSRVKLPDVHGKLTRLRRGDITYIKYEYDRYYDPEKKYTYPQ
                     RATIGKVCPDDDTMMIPNEAFLKYFPDAVLSGMEDRTERSSCLRVGTYAVMHKIVLDYS
                     LDKLLGQFFSERDMALLLDLASYSIVEESNVAQHYPDYAYNHPLYSSGMKIYSDASVSD
                     FFKSITKDKSTGFLNEWNAKRNRRERIYISYDSTNKNCQAGEIELAEFGHAKTDIGSAI
                     INYSVGYDLKNKEPLFYEAYPGSINDVSQLRTMLGKITGYGYKKIGFILDRGYFSRGNI
                     RYLDECGYSFVIMAKGMSSFISDLILENKGTFENKRSCDMNAYGVYGKTVQRTLFEGDE
                     KKRYIHIYHSISKDADEREHFENALRERTALLMSHQNETVEFGSAYEKYFYLHYDKDGV
                     FLYPEEKTTVTEREISLCGYFVIITSERMTAKEALHLYKSRDVSEKLFASDKSFLGNKS
                     MRSHTNEGVEGRIFTQFIALIIRNKIYTALQEENEKLEKKQNYMTVPAAIRELEKIEMT
                     RQTDNVYRLDHAVTAKQKKILEAFGMNEGNITYRAGEISNTLKKSNIQKERR"
     CDS             16117..16344
                     /locus_tag="ctg8_18"
                     /transl_table=11
                     /translation="MAREINAELLDTKIEKAQKDLVKAKHRYDAAAATLKDLLDKRDAL
                     RQKKLLDAIAQSGRSYEEIMQYLHSKSEEA"
     CDS             16349..16627
                     /locus_tag="ctg8_19"
                     /transl_table=11
                     /translation="MLTEYYFAVRYGDIIILLYHEDMMSVWELLFKNSQKEKALKRFLE
                     YCYMIDVKVAFEGLKGEKTKGLKATLKFAKEHDMCMTEAQIQGANNM"
     CDS             16864..18039
                     /locus_tag="ctg8_20"
                     /transl_table=11
                     /translation="MKSKKVKKILLIALTCVAISASVSAEAAMKSQITIESKNKYEQLK
                     ISESRVYGEYPTGDYKKIMLLPSVSKVEKFCFEDNLNIEEVEWMASVDTVPVFAFSTCP
                     KLKRVILSDNVKKIGQSAFIYCGELTSVKLPQNLQSIDFFAFADCRKLKTLYIPETVTE
                     IGAEAFINCDSLTVHGKKNSYAYYYCKMNGIPFVSEGTASKPETNRPYIKSVDSDIVNK
                     QIYVTIDLSGKVKNADGYQYQIYDGTKVLANKNSANTTCILKKVPTMGFARVRSYTVQN
                     GKKSYSRWSNEMRMPPVKLNKDNIKLIKITGKKKTVTAQFGNLKYSDGFDCVLKNADSG
                     ENIVLKNQKKNTVTFKNIKPGVYYLKAHAYTLLNGIKQFGVWSDNKKVVVK"
     CDS             complement(18120..19832)
                     /locus_tag="ctg8_21"
                     /transl_table=11
                     /translation="MPGTFNGTTLTISATPVDGALIPDKSATNVAGIAIVGSDMYCVKT
                     TGLKTTLLKTTDYMATKATAVKKDLNWFALGLTKIGNYLYMLAEDHKGYGGSTTIVKLD
                     TKGNQLGTYSINEICPKGALGITAADGTNEKFIIMHYADKSNAGTLAFSVVDWKAAEAA
                     STFTVTNSGFGYTTRLQDIYYHTSFGLFILTNNTFSTLQNRILVVDYHLTDDKGKKYTP
                     CSVINVNKTGEYKQYNLESICMKANHLVLASNVITSDGTAEDKFSVLEGITYSGKTYTF
                     ACGFKAGARVPTKVDPNYETTNLGCVSFNGNNTPYFIKQSQDKVAVLGYCKNYMNTSAG
                     VSHFKTFTDGLLGHANGMSCFNGKFFVVAGNNKVVAISSNKEDEEITYTVTPNDNDKSF
                     ALKAINYFYEANTALLLSVVDGTLKLYKCTFENEKNVKATYLCTLVNAGQPTSQDIFYH
                     NKLGLFVGTSNPHTVSGVTTKITTKNTLLHYNLKKLDDSKLLYPDFGFVTDIPAKDAQG
                     RKYNSFELESVALDQNNKLIAVCNVNVKDATHTSGLASTDGFFQYNTLEFITA"
     CDS             20356..21072
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 213.6; E-value:
                     5.3e-65)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_22"
                     /transl_table=11
                     /translation="MSEMTDAYVKLDKVSKIYGTKEVKIVAVDEISFEIAKGEFVVIVG
                     PSGAGKTTVLNILGGMDQATSGEVLVDGRNIARYNSRQLTGYRRNDIGFVFQFYNLVPN
                     LTALENVELALQICKNPLDAREVLEEVGLKDRLTNFPAQLSGGEQQRVSIARALAKNPK
                     LLLCDEPTGALDYQTGKAILKLLQDMCRERGMTVIVITHNSALTPMADRVIKIKNGKVS
                     RMTMNDHPTPIEEIEW"
ORIGIN
        1 tcaaaaagga aaaactttta ttaaaacgaa atcacagatt aacaaacatc cgtaaaaatt
       61 atttaaatca gaccatatcg gagatcgtaa atcgaaaacc aagatttata tgtattgaag
      121 atctgaatgt cagcggaatg atgaaaaaca gacatttatc caaagcagtt caggcacagg
      181 gattttttgg gtttagaaaa cagcttgaat ataggtgtag cgataaaggg atccagctta
      241 ttgtggctga tcggttttat ccatcatcaa agctttgcag ctgttgtgga aacatcaaaa
      301 aagatctgaa gttatctgac agagtttata gatgtgcgtg tgggaatatg attgacagag
      361 atttccaggc atctataaat ctcaagactt atggagaaca atttgcaggc tgacactgaa
      421 acgttaatgc aaatatgtac ggatacgtta gtccggaatt tacgcctatg gagagtacaa
      481 gaacttgtga gtagatagat atttatatca tcaaaagcat actcgttgaa gtaggaatga
      541 aacatagaag tttataactt tttataagtt ttcagtaacg gacagtaaaa tgaagttagg
      601 tattctggga gcaggaggca ttgcttctac tatggcgaaa acagtggcag gaatgaaaga
      661 tgtggaggcg tatgcggttg ctgctcgtga tctggaacgt gcccgggtat ttgcacagaa
      721 atatgaagta aaaaaagcat atggatccta tgaggaaatg ctggcagatg atgaggttgg
      781 actggtttat atcgcaactc ctcattcaca ccattatctg catgcgaaaa tgtgtctgga
      841 agcgggaaag catgtgcttt gtgaaaaggc atttactgta aatgcagagc aggcacaaaa
      901 attatttgac cttgcaaaag agaaaaagct tctgatcaca gaagcaatct ggacaagata
      961 tatgccgtcc agaaagatga tcaacgatat tattgaaagt ggtgtgatcg gagaagttac
     1021 ggcagttacc gcgaatctca gctatacagt aagtcatgtg gaacgtatcc gtaaaccgga
     1081 gcttgcagga ggtgctcttc tggatgtagg cgtatatccg atcaattttg cctccatggt
     1141 gcttggcgat aaggtaaagg atgtaaaggc tactgcaatc tttcagaatg gagtggatat
     1201 tctggacagc attgccatgg tgtttgaggg agaccgcatg gcaacccttc agtgtggagc
     1261 aagagaaatc tcagacagaa tgggaagtat tttcggaacc agaggatata tgcaggtgca
     1321 gaatatcaat aatccggaaa agattacagt gtttgatacc gaacataaag aagtggcttc
     1381 ttatgttgtg ccggaacaga tctcaggata tgaatatgag gtagaatcct gcatgaaagc
     1441 aattcatgag ggaaaaacgg agtgtccgga aatgcctcat gcggaaacaa taaggatcat
     1501 gaaaatcatg gacgacatcc gtaaatcctg gaattatgag attccctgta tcgaataaaa
     1561 agtgtggaat aatcttataa aaaagaccag taatgttttt gacatatacc cgaaacatta
     1621 ctggcttttc tgatattcat gaccattata caacatgtca ttccgtaatt acagaaacat
     1681 tcccgtccag tggtatatta atattaatta ggtaaattga tacttttata ttttattatc
     1741 tggaggagaa gaatgaaaag taattacaaa atttttacag cagttttttt atcggcaatt
     1801 atgacagcag cagctccgtt aacagtatgt ggggcggaag ttttttcggc gggagaatct
     1861 ttcagtgatg gaacggggag tattcctgcc atattgacag atatggttct gccggatgga
     1921 gagattggaa cggaatatca ggtacagctt gaagctgata cagatgtgaa ctggagtctg
     1981 gaagagggaa gtgagcttcc ggcgggattt acgttgtctt ccgggggagt gatcagtgga
     2041 atgccacagg aggaagggag tttcagcttt actgtacagg cggacaatgg tattggagtt
     2101 tcttcacagg aactgagcct ttatgttgca cagcgtgagc aggaacctgt tataaagcag
     2161 tatgagctga catcaggtac tgctttgatc gatctgggaa ttcatgcaga gggagaacag
     2221 tcacgtaagc ggttatttct ttataatgca ggaacagatt cgcttcatct ctctgatttt
     2281 ccgcagagca gatattttga tttttcctac gcaccgattt tcgatacaaa tacggatgaa
     2341 gaaatgcagc ccggaagttg tgcggctgtg gacattgatg ataagaagaa tctgcctgcc
     2401 ggaaattatg aagagacagt gacatttgag acaaaagagg gtgcttcctg taaggttact
     2461 ctgaaagtaa ttgtgggagc ttcctctgaa aaagattatg agctgagtat agaaacaggt
     2521 acagaagaag aatttacaga aagcgatttc tatgacccgg aatttcgtgt ggagaagtat
     2581 gtagtggtca gaaattcagg aaaaaaggaa accagaatac ggatagatac ttctggtctt
     2641 aagaattttg aagtggatga ccagatggca aagtggacag aagattatga ggaacaggat
     2701 tccaaaaagc tgctgaaacc gggagaaacg ctttattttt atatattgcc gaagcaggaa
     2761 tacggaattt atgatgaaac gtttgcattt ctcgcagatg acggaagcag atatcctctt
     2821 catgttacaa tgaacagaga gaagaatccg acagaaaaga agcagctgga aattactgaa
     2881 aagtctgccg ggggttttcc gacaatgcag tggggctata agacacttcc ggaagcaaag
     2941 acatatattc tgaaaaatgt tactgataca gatatgaagc tgtcttttaa ccgtagtaaa
     3001 gaatgtagtg tgttattatc tggaaatgct tatctggcac ctggggagag cacagaactg
     3061 agactctggc ccaaactggg gctttcggtg ggaaaatata gttttcaggt gactgtgact
     3121 gcgaaaacag tggcaggaga acacctgaca acgcagaatc tgtataattc ttttattgta
     3181 ggagaccgga cttatcaggg actggcagat gctgttgcgc ctgtgaccgg aattaccaat
     3241 ggtgcagaaa aaactgctga tgctttgcat ctgccgaagt cgctggaagt ctatggcgcc
     3301 gaggtgaatg gagagaaaac aacattttct gcgtctgtga agtgggatgt ggagaattgt
     3361 gcttatgatc cgaaaagcaa ggcagctcaa agttttctgg tcaacggatc tctggaactg
     3421 aatgaggatg aaaataatga agggctggac actgccgtac agataatggt acaggtggat
     3481 gcttatcaga cattaaacag accagttatt gatacgcggt ggaccagagt gatcacaaat
     3541 tatgcaatgc tttatctgag agatctttcc aatgaagcgg acggctatca gtttgtgaca
     3601 gcgaaatctc agaaggatct gaaaaagggg aattatactg cgcagacaaa aattacaaat
     3661 tctgaactga atcaatatcc tgagctgaag tatattccgg agggaacaca tagtctttat
     3721 tgcagggcat acaaagagaa cagcagccat gttatggaat atggggaatg gtcagacggg
     3781 gttccggtta cggtaaaggc aaagactccg gacgcacctg tggttcagaa ggtgcaggtg
     3841 aagaaaaatg atgtcagaat agtacttaac agcaagggtg aggaaccgga cggttacgat
     3901 gttgttgctg ccagaagtaa gaacggaaaa gaaccatcgg attatataaa ggtaaagagt
     3961 gggtattccg gaagcagtaa agagcttatc ttacggggcg taccggcagg aacgtggtat
     4021 attggcgtac atgcttataa atatctgaat gggagcaata ccaaagtgct cagtaaatgg
     4081 gcagaggtca ggaaggtaac tgtaaaaaca agccttgtaa caggaaaacc tgctgttaaa
     4141 tcagctaagg tttccagaca gggaacaaaa agaaacgtgg cggtgacgtt tactgttcca
     4201 aagtcctgtg atggaacaga ctgggtactg gcaaagaaag tttccaaatc tgataatggc
     4261 agctatactg gtgtaagcag ttatgcttac acaaagaaaa atcagacaaa aaccacggtg
     4321 gtctttaaaa atgtgaagcc cggagtctac taccttgcag gacgtgccta tgtaaaaggt
     4381 tatgcaaaaa gttatacgaa atggtcgaaa ataaagaaaa tagttgtgaa ataagtactg
     4441 ctgccatttg tttcacagag atttcacttt taagaaaaaa gatattcccc ttttaccaag
     4501 cgtttataag gcaaaattat ggggtaaaga ttttggaaaa aaatggggta catttcatga
     4561 cagataaggg acatatgagg catcgaagcc tgtgaagtat gtcataatga acaggaaaag
     4621 cacattatga taaaggcatc gacattttta acaaatgtag aaaggataac aaaatgaagc
     4681 agaaaaagat tgcaattatt atggcaggga ttttagcagc agcggctgct atgactggct
     4741 gtgcggaaca gaataaaaca gagacacagg ttgattatac gcagaactca caggagaaat
     4801 ccgaacagac aaaacaaaaa acagcagaaa aatctcagcc ggataaaaaa caggtaaata
     4861 aaagtacatc cattggaaaa gaagattcaa atcagactgc ggataagaag acgaaaatat
     4921 ctgcttcatc caataatgca ggcgacgtac agaattcaga gaatggaaca gacagtactg
     4981 cgggaactga tacagacgat tcccagacca caggggtgga cacttctgca tctgaagata
     5041 atggttcaac aggtaatggt ggtactcaat ctgatcagag ggcagatcag gcaatgatat
     5101 atgacagtga gggaaatgga aggctgattt ctgaagctga tgatggaaac tggtatgaca
     5161 gtgacggaaa ttactatgga agctgggaag atattgaaga tgctatggta aatgaaaatg
     5221 gtgtcacaga tcaggatggc aataaatatt actggacagc acctcacgat gcatcagaag
     5281 aggtcacaga tccgtatgac ctgtattcct gggatccggg aaccaattcc tatataccgt
     5341 ttcaggctgc ggaatctgac tgtagtcctg taggcagagg aaacggctgg tattattatg
     5401 atgaagacag cggcgaatat gttccgtggt agaatataaa aatgcgaaaa gaagcagttt
     5461 tgagaccatt ttaatgggtt tcaaaattgc ttctttttgt tatatacatg aatagtgaag
     5521 gggtatatcc gacagaatca ggggacagaa ttctgccgga tgtttatctg gtaaagatca
     5581 gctgatcagt ttcaggaaag tatttctgtc acaggttccg gaaactgtta agccctgtgc
     5641 cttctggaat gcctttacag cagagagaag tcctgagcca aaggtaccgg gaatctctac
     5701 accgtttgga tcataagcac gtaaaagaag gagaatctca gcggcagtta ccatatactg
     5761 tgtttcacca ttttttacat aatgctgtcc aagagcattg tctgtgtttg ttccccagat
     5821 accgtctaca tccagaccgg caccataatc cctgttcaga gctgtctgaa gaactttaac
     5881 gcctgctttt ttggtagcag cgtctctttt tccggtaata gagattcctg cattggcgaa
     5941 tttattggca taaccctgac ctttgcggat ttttgcattt cctgcagttg gctgaggttc
     6001 aggatcagga tcagtagttg aagaatcttc agtataacgg agaacgcaat cccaggggaa
     6061 attgtaataa ctctgaagtt tgatctcttt tccgctctga tctccgggtt taccaccatg
     6121 atatccatta ttttcatttt tgctggcaga taccacctga ccattaccaa tgtgcattac
     6181 tgtatgactt gcgatgttta ataatacatc gccacgtttc atgccacttc ctgtgctgag
     6241 attaactttg gaagttacat ccttaaagcc gcaggacaga aaaacggatt tcatatttcc
     6301 tgtataagtg gctccttttg tttttacagg aacaccagcc tgctgccatg cggagattac
     6361 cagtgaagaa caatcgtagt ccggtcccca tctgttatcc tgatcatatc cgtgtgccgg
     6421 atcgtttgcg attctaattg cccatgttac tgctttttct gtttttgtca tttttttatc
     6481 ctcctgaaat ttgattattt atttgctcac cggtgataca tcttataaag agtgagaaaa
     6541 gggaaaaatg taaacatgaa acagaaaaaa ataaaaagca tttcctgatt gttgcttcga
     6601 ggtcagaaaa atgcttttcg aggacaaaaa cacgaaaatt gtcgaattgt aattatattt
     6661 aatcctgatg agaggcctgg tatattttca gtatttttac aatgtattca gtctggcgtt
     6721 cacccatttg attcatgatt gaaatcgcat cctgaatagc cgggctttga atatctttat
     6781 tatgaggaag cagatcataa agaaaatagt caagtcccac atcaagaatt tcagaaagct
     6841 taaggagatt ttcaatagta ggcatatact tacctgtttc aatccggctg atcgtactta
     6901 cagataaacc acttaattct tccaggtgtt cctgggtaat atttctgttg atccgagctt
     6961 ctgcaattct ttttccgata gtattgtttt tcataaataa aaatcctttc ctttgataaa
     7021 gtttaacaga cggaattaaa tatgtataag gatataaatg acaagcgact aatcaaattt
     7081 gatatgtttt atgacaggag gaatatagga atatggacga atatacaaag gatttgtata
     7141 ccatgatgtt ttctttacag actttgcaaa atcagggaat tacaatcaga gaaactgtat
     7201 ataaaagtct ggacaaatta ctgttatgga ataaagaatc tgaaaacagt aaatatctcg
     7261 aattagcgtt gcttcatatg caggcttatg ctaatatggg atttgcttta gatgaagaaa
     7321 ataagacaat acgtgagata ttaaaaaaga caggaaagac cagagaagac tttttcccga
     7381 aaggatatct tcttggaaag agaattaaac tgaccaagtc acaggttcgt ggtatgattg
     7441 gaagatggag accttccaga gacagtccga tgacaatcgg agaactggtg gatgatatca
     7501 tcagaaaggt aaaaaaccat gaggaaggca gatacattta tcagtatcac agaactgatg
     7561 tgacaaccaa aggggatatc gaggtttatg agctggtcat caataaggat gaaagttatt
     7621 tttatgatgt gaagaaattc agattttata cattcatgga ggaataattg ctatgataag
     7681 aataatgatt ctggatgatg acgaaatgta tctgaaaaaa gaaaaggata tcacagaaca
     7741 gtattttgca gagaaaaacg tagattgcac ggtaacgata taccagaatg tggaatggtt
     7801 tctgctggga ttgaatgaag aaaaattcga tatgtatatt ctggatatcc ggatgcctgg
     7861 agaaaacgga atagaggcag cgagggaaat tcgcagactt tatccggatc cggttattat
     7921 atttattaca aattttgtgg attatgcaat agaagcatat gaggtaaaca cctatcgtta
     7981 tatccccaaa gagtgtctga aggaaaaact tccgcaggct tatgatgcgc ttcttcctgg
     8041 aattatggag aaagaagagc ggtactatat cataaataaa agaaatgaag ttgaaaaact
     8101 ggcatattct gatattttct atatgaaaaa agaaggaaaa tatgtcattt ttgtgcacag
     8161 gcgtggggaa gtaaagatca gagcaagtct gtcaacagta gaaaaggaac tgaattcaaa
     8221 agaatttatt atatctgaca gaggatatct tgcaaacatc caacatgtga tgaagatgaa
     8281 aggaagggat ctttatatgc gggacggtaa tattattaca gttggcagag aaagattcaa
     8341 aggtgtcaga gaagcaattc tgaattactg gggggtatga agaatgctga aagttttatt
     8401 gtatggactg gcaacgttta tggagacagg gataggtgtc tggatattta gccagacgtt
     8461 ttctgaacga agaatattag aaaaaaaata ttatgttcta gaatggctgt tgtattcttt
     8521 gatttttttt ggaatttata atttttctgt ttcattatgg cagattgata aaaaaataga
     8581 aaaatatgtc ataaaagtta tttgtatata cataattgga ttaattgcag gaattatata
     8641 tgatattttt tttgtaaaga aaaaggagat ggtcttaaga agaatattat atatcggcat
     8701 gatattttgg ttaactgccc agtattgggc tggatatcaa tcgttgttaa tgattattct
     8761 tgggagtgga ataattgtat tatatgtttt ttgctacttt gattgcacat ttaaacaggc
     8821 atatgtttgg aattttttct atgcagttaa tataggattg ataaaagagg cttatgttgt
     8881 atatgcaggg gtgtttaacc ataaacagtg ggatgatttt tattcatatc cgagaggaca
     8941 tacatatcag gaagttatat tttggatttt aggctgttta ttcatatttt ggataattaa
     9001 atttattttg tcagtaaaca gtataaaagg aatattgcgt acacgtctga aggaactttt
     9061 tattattgga ttgttagagt atgttttatt aatagttagc atcatataca aatttggtac
     9121 gattaaaaag gaaaattttg taatgaccgc atgtttatta gcagttagta atatagcatt
     9181 gattggtgta tatgttaagt ttcaaaaaaa gaccctagaa atgagaaatc agattttaga
     9241 tatgagatgc aaattaatgg aagaagaata tgaagaattg agaatgtcat atgaccggta
     9301 tcggtgtttg gtgcacgatg aaaaacattt gcttttatat ataaaagaat gcctggaaaa
     9361 tggagaactg gattcatgta tcactttttt gaatcattac aagagagaaa gcattagata
     9421 tagtggagta gcgtggacag gaattccaga aataaatttt atgttgaata taaaagtgcg
     9481 aaaaatggaa gaaaagaata ttttttttaa agtagattca aaaatagaaa aaattccgat
     9541 gaaagacata gattttgttg tactcctagg aaatcttttg gataatgcaa tagaagctgc
     9601 tgaaaagtgt gaagagggaa aaggtaaaat tacgtgtatt tttcgaaata ttaatgatat
     9661 gtttattttt aaagtaaaga atacaagcat atataaacct tatgaaaaaa acactaaatt
     9721 ttatacaagt aaaaaagaga aagatgagca cggatggggg attgaaagtg tcaaacaaat
     9781 tgtaagaaag tataatggtg aaatagattt taaatatgat aaagattttt ttgaagtaga
     9841 aataataatt agcgataata cataatggga gagtgacggt tatgaacgaa atgaatgata
     9901 aaataatagg aaatgtggaa aaagaattag atgaaataga gataatagat acggaaagta
     9961 tagaagagaa attgtctttt attgtatatg gaactatagt gtgttgctga aattggatta
    10021 tttatgcaga aaaaatcgaa ctatgtttct taaaatatta atcttagatg tacatcggca
    10081 gaaaaatttt ggaaatctaa aaggaagtac gccaaaagaa caatatgatt attatgaaaa
    10141 aaaatatctt aacaatgcaa catatgtaaa atctttactg caggaatatc ccgagttaaa
    10201 acgtctgctt gaattaaaaa ataactctat ccagagagca gaatgtgaaa tcaggaaatc
    10261 tctttatgca gaaaaagaac agatacaaaa aatattctgt gatggaagaa agttttccgg
    10321 gactgtggga atttacatgt cgaaaggcga tacacacaga ggaggacgaa gtgtggcgaa
    10381 ggtagaattg gataatggaa caattctgta ctataagcca catagtcttg ataagaatat
    10441 aaaatatcag gaactttata actatttatg cagaaaaaca ggaatttcct gcaggacggt
    10501 acaatattta tctcatgatt cctatggatg ggaagaaaaa attgagaata ttccctgtaa
    10561 aaacgaaagt gaggtggagc attattattt cagaatgggc atacatctgt ttttgggata
    10621 tgcccttgga gcaacagatc ttcatggtga aaatattatc gcacatggag aatatcctgt
    10681 gattatcgat atggaaacgt atccgggata tttaaaacaa caatcagaaa aagacggaag
    10741 tagtgtagaa gaaaaaataa acaaaagtac agaaataaaa ttggcaaatt cggttataca
    10801 tacaggaatg ctccctgttc tcacatgggg cagaggaaac agcagagttc ttataagtgc
    10861 aatgggaaca gaggaaaaga taaaaacgcc gtttaaactt cctgtggtaa aggatgataa
    10921 aacatctgat attcacatag aatatgaacc tgtggaaatg cagataaagg aatgcattgt
    10981 aagactaaat gatcaggtta tcaatgcggc agattatacg gaatgcatta tcagaggatt
    11041 ttgcagagcg tacatggtga caatggcaga taagaaagtg gaggtgatgt tgtccggctt
    11101 ttttgacgga cgttccagag ttgtactgcg gcatacccaa cagtatgcaa tgtatcttat
    11161 ggcttcgttt catccggatt atatgaagtc aagagaatgc aggaaagctc ttttgaatgt
    11221 gattcacaaa gagggggaat cttcttttat gaaagagatt catgattatg aaattgacag
    11281 ccttctggaa atggatatac cctgctttga gattgatgcg aacagcagat ctgtttatga
    11341 tggaaatggc ggagaacata aagaatatct gccctgtact ccttatgagt catggcgaat
    11401 gcatatgaag cagatgagtt actctgatat ggaatgtcag tgtgattata tcaggctgtc
    11461 catggaaatg ctgaaggcat ctgatggaaa gaaaaagatg tttccgacca ggataaaggg
    11521 atatgacaca gataaagagc gcaaaatata cagtcagatc agaaagatag ttcatcgaat
    11581 ctgcagcaga gcaattatcc gggaacagag cgccggctgg gcgggtctgc aattctggga
    11641 taatggtcac tggaatctca gatcaggtgg aatatattta tatgatggaa tatccgggat
    11701 agtcttgttt cttgcaaaat atcttcatga ttttgaagaa aagaatgcaa gtgcagaaga
    11761 aatttatcat cttgctgttt tgagattgaa agcttataca gatgaaatac acaaaaaaca
    11821 gatttatgat aaaaatcttc tgacaggtat tgtaaatgga gaaagctcgg tggtatatac
    11881 ctatctttat ctgtttaaac ttacaggaaa aagagtgtgg atgatttatg cggaaaagca
    11941 tttcagcatt attgagaggg tatggaaaga agattcacaa ctggattatc tgagcggaaa
    12001 tgccggagct attgtagtgg cagtgatgtt atataaagaa accggaaatc tgaaatatta
    12061 tgaaatagcg gcagatatgg aaaaagattt gtggaagaaa ggacaggaaa ccggaaatgg
    12121 atacggatgg agattaaaag gaacagacgg accgctggct ggaatgtctc atggcaacag
    12181 tggatttctg atggcttatg cagcgttgta tgaatgtaat cataaagcgg aatatgctga
    12241 taaaatacag cttttgctga gatatgagga ttctctgtac tcagagaaag ccggaaactg
    12301 gaaggattta cgagagagtt caggggaaag cttcatgaat gcatggtgcc atggggcgcc
    12361 gggaatcctg ctttcacgaa tgaaactgga agagctgttt cctgaggata tgcagattaa
    12421 aaaagacagg ttaaatgctg cagactcttt gttttatgga gaacaggatg aaaaaatttg
    12481 tctgtgtcat gggatgtccg ggaatttact tattatgaag aagtaccttc gaaaatatgg
    12541 taataaaaaa atgaaggagc aatatgaggc gttatgtgac tgccttttat ttcaactgga
    12601 tcacccggca aaaatatctg ggacagaata tctgaatctg gcttttatga atggcatttc
    12661 cggtacggga atggcattaa tggaaatttt atgaaaacta agggaacacc tgcagactgt
    12721 aaatttatgg tcagcaggtg tttcttttat ttgttttcgg aaatatatct gagaattagt
    12781 ttcttcttca tccgattgac gtactggcgg gacagcttca gtttccgggc aatctgggca
    12841 tcgcttttat cctgataaaa gtacatggac agaatttttc tctggacact gtccgaaggg
    12901 taagagttga tatatgcggt tacatcataa taggtgtcat caaaactgtc gggagcctgt
    12961 aatgaaacag aacaagaatc aaaatcatct ttttcaggtt cggaaagaca actgcggcaa
    13021 agggaacgat atctgttttc gacagaggtc tgcatgtatc tgatacattc accttctgag
    13081 gatgaagaac ttaaatatgg caatgtcttt aacaaagtaa gatacaattc ctgtgtggaa
    13141 tcttcgcgtt ccatgcagtg aatccgggat gcatatcctt tcacaagcgg ttccatacgt
    13201 ttgagaattt cactgtctga atctgggata ccattttgat aattttggat aagttctgtc
    13261 agtgttttca taggtatcta cctccttttt aggggaagta gtaagaaaac tgctgatcag
    13321 aaactaaaaa agaaaaaaat ttgtgagttt acaaatggaa gagaaaaaac tctttattaa
    13381 gtgaggttgc aaatttagat cagcgatagg agaagaaata catggtaaaa agagatttgc
    13441 aaaataattg tagagaatag aaatatgctt taaattaaaa cggtaataat aagattagaa
    13501 aagactttta gtagacaaaa catagaaaaa gtttgcataa taaaagaaga ttaaggaagg
    13561 aggcagaaac catggaaaca acggttatga atgtggcagt ttcacaggga atctgggctg
    13621 tgcttgcggt ttttcttctg atttacattg tgaaatcaaa tgaacagagg gatacaaagc
    13681 aggaagaacg agagaaaaat taccagacgg tgattgagag tttaactgag aaatttcaga
    13741 ttctgaatca ggttcaaagc gatctgaaag agattaagga taatcttttt aacaaaaatt
    13801 aaatagggaa aagaaaaaag ccttttctgc aggatatatt tttccagcgg agagggcttc
    13861 tgtcatttta ggtaagaaaa taggttaatt tgagaaaaat atgtttacta aaatggtaga
    13921 tgaatataag cataacattc gtgtccatta gaatactttt aatcccagat ttacagatgt
    13981 tcgtatagta aatggtatat tatgataata aaacctgact tttgggtagt gtaaaataga
    14041 ttaaaaaaaa tggccgcaat ccaagtgttt atgcgagggt gtaaaaattc ttgtgtctat
    14101 ggaaagtaaa tctttctgat aagaaataga tatgtaaaat tttgctgtcg aattaatgat
    14161 tatgcggctg tcgaatatat ctttgtactt acagtattgc catgtaggaa aattatatac
    14221 atcattttcg atttttttgc atgacaagta aggcatcatg attaccttaa cttccaaaaa
    14281 tgagtagccc taacgaaaat aaaattttaa aaaagcccgt atttctgcgg aaattattgc
    14341 aaaaatacgg gttgtgctgt acaataaatt tagggctata taaacctgaa taaaggaggc
    14401 aaatatgtac ctgaaatcaa gagttaagct accggatgtg catggaaaat tgacccgatt
    14461 aagacgcggg gatatcacat atattaagta tgagtatgat cgctattatg atccggagaa
    14521 aaaatatacc tatccacaga gagcgactat aggcaaggta tgtccagatg atgacactat
    14581 gatgattcct aacgaagcct ttctgaaata ctttccagat gcagtcttat cagggatgga
    14641 agaccggaca gaacgtagca gctgtctgcg ggttggtaca tatgctgtaa tgcataaaat
    14701 agtattggat tattcgttag acaagctgct cggacagttc ttctctgagc gggatatggc
    14761 attattgctt gaccttgcct cttactctat tgtagaagaa agcaatgtgg cacagcatta
    14821 tccggattac gcatacaatc atccactgta tagttctggt atgaagatct atagtgatgc
    14881 gtcggtaagt gatttcttta agagcatcac caaggataag agtacaggct ttctgaatga
    14941 atggaatgca aagagaaatc gaagggagcg tatttatatt tcctatgatt ctacgaataa
    15001 gaactgtcag gccggagaga ttgaactggc tgaattcggt catgccaaga cagatatcgg
    15061 ttcagctatc atcaactatt cggttggata tgatcttaag aataaagaac cactctttta
    15121 tgaagcctat cctggaagta ttaacgacgt atcacagctt aggaccatgc ttggtaaaat
    15181 cactgggtat ggctataaaa aaatcggttt cattttggac aggggatatt tcagccgtgg
    15241 aaatatacgc tatttagacg aatgtggtta tagttttgtg atcatggcta aaggcatgtc
    15301 ttctttcata agtgatttga tcttagagaa caaaggaacg ttcgaaaata agcgctcttg
    15361 tgacatgaat gcctatggtg tgtatggaaa aacagtacaa aggactttat ttgaaggcga
    15421 tgaaaaaaag agatacattc atatttatca tagtatttca aaagatgctg atgaacggga
    15481 gcattttgaa aacgcactga gagagcggac agctttgctg atgtcacatc agaatgaaac
    15541 agtagagttc ggttcagctt acgaaaaata cttttatctt cactacgata aagatggcgt
    15601 gtttttatat ccggaagaaa aaacaactgt gacagaacgg gaaatatcat tatgcggata
    15661 ctttgttatt attacatccg aaaggatgac cgcaaaggaa gcactgcatc tttataagag
    15721 ccgtgatgta tctgagaaac tttttgcctc tgataaatca ttccttggaa acaagagcat
    15781 gcgttcacat acaaacgaag gagttgaggg aaggattttt acacaattca tcgcactgat
    15841 aatccgaaac aaaatttata ctgcattaca ggaagagaac gaaaaacttg agaagaaaca
    15901 gaattatatg acagttccgg cagcaatcag ggaacttgag aagattgaaa tgacacgcca
    15961 gacggataat gtataccggc tggaccatgc tgtaacagca aagcagaaaa aaatcttaga
    16021 ggcttttggg atgaatgaag gaaacattac ttatcgagcc ggagagatca gtaatacact
    16081 taagaaatca aacattcaga aagaaaggcg gtaaatatgg cacgtgaaat aaacgcagaa
    16141 ctactggaca ctaaaattga aaaagcacag aaggatctgg tgaaagcaaa gcatcggtat
    16201 gatgctgcgg cagcaacatt aaaagattta ttggataaga gggatgcact tcgccagaaa
    16261 aagttattgg atgctatagc acagagtgga cggagctatg aagaaatcat gcagtacctg
    16321 cacagtaaat ctgaagaggc gtgatcaaat gttaacggaa tactattttg cagtcaggta
    16381 tggagatatc attattcttc tctatcatga agatatgatg tctgtatggg aattattatt
    16441 taagaacagc cagaaggaaa aggcattgaa aagattttta gaatactgct acatgataga
    16501 tgtaaaagta gcattcgaag gtttgaaagg agaaaaaacc aaagggttaa aggcaactct
    16561 taaatttgcg aaagaacatg atatgtgtat gactgaagca cagattcaag gtgccaataa
    16621 catgtaaatt tccagcccga gatgctttta gggctattcc aggctggaaa ttaaggcagc
    16681 tgctaaacaa aaggctttca gactacaggc gaacatatgt tgctgcaaaa ctgtggagat
    16741 taatttaaat ttgcattttg gttcggggtc attagaatac ttttaatacc agaaatacag
    16801 gatcttttat agttagtgat atactatgat aatagatgaa tattattgat tggaggagat
    16861 tctatgaagt caaagaaagt aaagaaaata ttgttgattg ctttaacgtg tgtagcaatt
    16921 tctgcatctg tctcagcaga agctgctatg aaatcacaga taaccattga aagtaaaaat
    16981 aagtatgaac agttgaaaat ttcagagagc cgtgtgtatg gagaataccc aactggagat
    17041 tataagaaga taatgcttct tccttcggtt tctaaagtag aaaaattttg ttttgaagat
    17101 aatttgaata tagaagaagt agagtggatg gcttcagtag atactgttcc agtttttgcc
    17161 tttagcacat gtccaaagct taaaagggta atactttctg ataatgtgaa aaaaattgga
    17221 caaagtgcat ttatatactg cggtgaactg acgagtgtta aacttcccca aaatcttcaa
    17281 agtatagatt tttttgcatt tgctgactgt cgaaaactga aaacgttata tatacctgaa
    17341 acagttactg agataggtgc tgaggcgttc ataaattgtg attctctaac agttcatgga
    17401 aagaaaaatt catatgcata ctattactgt aagatgaatg gtattccttt tgtaagtgag
    17461 ggaactgctt caaaaccaga aacaaatcgt ccgtatataa aatctgttga ttcagatata
    17521 gtaaacaaac aaatctatgt tacaattgat ttgagcggaa aagtaaagaa tgcagatgga
    17581 tatcaatatc aaatatatga tggtactaag gtattagcta ataaaaattc tgcaaacaca
    17641 acctgtatat taaaaaaagt gccgactatg ggatttgcca gagtccgttc ttatactgtt
    17701 caaaatggta aaaaaagtta tagcaggtgg tctaatgaaa tgcgtatgcc tcctgttaaa
    17761 ctaaataaag ataatataaa attaataaaa attaccggga aaaagaaaac agtaaccgca
    17821 cagtttggaa atttaaaata cagtgatggg tttgattgcg tacttaagaa tgcagattca
    17881 ggagaaaata ttgtattaaa aaatcaaaag aaaaatacag ttacttttaa aaatataaaa
    17941 ccgggagttt actatttgaa agcgcatgca tatacgttgt tgaatggtat taaacagttt
    18001 ggcgtatggt cagataataa aaaagttgtt gttaaataga aaattggaat tataaaaagc
    18061 aggcgaaaaa ctgcctgctt tttataatgg aaatttatgc tgttattgat gtagcgaaat
    18121 caagctgtaa taaattcaag cgtattatac tgaaagaagc cgtcagtgga tgctaaacca
    18181 ctggtgtggg tagcatcttt gacattgaca ttgcacacag cgattaattt attattttga
    18241 tccagagcca ctgattccag ttcaaaactg ttatatttgc ggccctgagc atctttagca
    18301 ggaatatctg taacaaatcc gaaatccgga tataaaagtt tgctatcatc aagttttttc
    18361 agattataat gaagcaaggt gttttttgtt gtgattttag tcgttactcc acttacagta
    18421 tgtggattac tggttccgac aaaaagccct aatttattgt gatagaaaat atcctgggat
    18481 gtaggctgac cggcgtttac cagtgtacaa agataagtgg cttttacatt tttttcattt
    18541 tcaaatgtac atttatagag ctttaatgtt ccgtcaacaa cggacaataa taaagctgta
    18601 tttgcctcat aaaaataatt aattgcttta agagcaaatg atttatcgtt atcgttggga
    18661 gttactgtat atgttatttc ctcatcctct ttgttactgc tgatagcaac cactttgtta
    18721 tttcctgcga caacaaagaa ttttccgtta aaacagctca taccgttggc atgacctaat
    18781 aaaccgtcag tgaatgtttt aaagtgagat acacctgcgc ttgtattcat ataattttta
    18841 cagtagccaa gaacagcgac tttatcttga ctttgtttta taaaatatgg agtattgttt
    18901 ccgttaaagg atacacatcc cagattagtt gtttcatagt tgggatctac tttggtaggt
    18961 acacgggctc ctgctttaaa accgcatgca aaagtatagg ttttaccgga gtaggtaatg
    19021 ccttccagca cagagaattt atcttctgcg gttccatcag atgttataac attggatgca
    19081 agcacaaggt gattggcttt catacagatt gattcaaggt tgtactgctt atattcacct
    19141 gttttattta cattgatgac cgaacatgga gtgtattttt tacctttatc atcagtaaga
    19201 tgataatcaa ctaccagaat acggttctga agtgttgaaa aagtgttatt tgtcaggata
    19261 aataatccaa atgaagtgtg atagtaaata tcctgaagcc gtgtggtata accaaaacct
    19321 gagttagtaa ctgtgaatgt acttgctgct tcagcagcct tccagtctac aacactgaaa
    19381 gctaatgtcc cagcattgct cttgtcagcg taatgcataa tgataaattt ctcgttagtt
    19441 ccgtcagctg cagtgatacc taatgcgcct tttggacaaa tttcattgat actgtacgta
    19501 ccgagctgat tgcctttggt atccagtttt acgatggttg tagaaccgcc gtaaccttta
    19561 tggtcttctg caagcatata cagataattt ccaattttgg taagtcccag agcgaaccag
    19621 ttcagatctt tttttacggc agttgctttt gttgccatgt agtcagtcgt tttgagtaat
    19681 gtagttttaa gaccggttgt ctttacgcaa tacatatctg accccacaat ggcaattccc
    19741 gctacatttg ttgcactttt atcgggaatc agtgcaccgt ctacgggggt agctgaaata
    19801 gttaaagttg ttccgttaaa tgttcctggc ataatttttg cctcctttaa attttttgaa
    19861 tttgcaaatt cactatataa agatgctgct ttttgtgatt tgtaaaccat aagtgtgtat
    19921 atgagcatga tttttttctt tcatgcggaa atcaggtaag aataaaaata aagattcgag
    19981 gtcagatgat gtatgtttag tcccactttt atattttcgt catcagctta atgtaaaata
    20041 ataacgggta aagaagatat aagatgttct ggtacacgaa ataagaagaa aggagatatg
    20101 ccacatggtt aaaatgatga accgcctgag atgatcaggc ggttttgaag tatctggatt
    20161 ttttatgaat attttatttt taattacagg tataatgtgt tacaataaat ataaccatta
    20221 agactaccag gcaggtcaga atttgacctg cctgtaaata aatacggaaa taaatcgggg
    20281 tcaaaagaat cgttaataat tgtaacaaaa taaaattacc ggtgtagcaa aaataaaatt
    20341 acaggggaaa tgcggatgag tgagatgaca gatgcatatg taaaactgga taaggtttcc
    20401 aagatatatg gaaccaaaga agtaaagatc gttgcagtgg atgagatcag ctttgagatt
    20461 gccaagggag agttcgtagt gatcgttggt cccagcggtg cgggcaagac gacagtgctg
    20521 aacattcttg ggggtatgga tcaggctacc agcggagaag ttctggtgga tggaaggaat
    20581 attgccagat ataacagcag gcagcttacc ggttatcgga gaaatgatat tggatttgta
    20641 ttccagttct ataatctggt gcctaatctt acagcgctgg agaacgtaga actggcattg
    20701 cagatctgta aaaatccgct ggatgccagg gaggttctgg aggaagtggg actgaaggac
    20761 agactgacca atttcccggc acagctttcc ggtggtgagc agcagagagt ttccattgcc
    20821 agggcactgg cgaagaatcc caagctctta ctgtgtgatg agcccacagg tgcactggac
    20881 taccagactg gtaaggcaat cttaaagctt ttgcaggata tgtgcaggga gcgtggaatg
    20941 acagtgatcg tcattaccca taactcggcg ctgacaccta tggcagaccg tgtgatcaag
    21001 atcaagaacg gaaaggtttc caggatgacg atgaatgacc atcctacacc catagaggag
    21061 attgaatggt aggtgatgaa tatgaaagca atgcataaag atttctggat ggagatacga
    21121 aaaagtaagg ccaggtttat ttccatattt atgatcgttg ctttgggagt tgcattcttt
    21181 tccggaatac aggcgtcgtc accggatatg cgcttctcag gtgatgccta ttatgatgaa
    21241 accaatctta tggatatcaa agtaatggga actctgggac tgacggagga tgatgtagct
    21301 gccattaagc aggtggacgg agttgagaat gcagagggcg cctatggtac agatgtaatg
    21361 tgtggagaag gcgagaagca gaaggtactt catgtggaag ctgtggatca aaccatgaac
    21421 cggatctcag tgacagaggg aaaagctccg gaaaaaagcg gagagatttt ccttgactgt
    21481 atttttgctg agagcaatgg atatcaggtg ggtgatcaga ttaccctgaa agagggcgga
    21541 gacagcgaac tgctgaaaaa gacagattac acagttgtgg gtttaggtga gagtccgctt
    21601 tacatatcct ataaccgggg aaactctact cttggttccg gtgaggttaa tggatttgcc
    21661 tatgtgctcc ctgaggattt tgaccaggag gtttatacac agatctatgt gcaggctcat
    21721 ggggcacagg atctgatcag ctatacagat gcttatgatt ccctgataga gcgagtgcag
    21781 gagcgagtgg aggggattga ggcagaacgg tgtcaggtca gatatgatga gattgtagag
    21841 gaagccaatg acaagcttgc agatgccaga caggaacttg aagacggaaa gaaggaagct
    21901 aatgagaagc ttgcggatgc cagacaggaa ctggaggacg gcaaaaagaa gttaaaagac
    21961 ggcaagaagg aatataagga tggcaagaaa aagcttgcag acgcaaaaaa ggaactggag
    22021 gacggaaaag cccggcttgc agatgcaaag aaggaattag aggatggcag atcccagctt
    22081 gccagtgcga aagagcagct tgccagtggc agagcacaga tcgcatctgc aaaggaacag
    22141 ctgaatgcag gatgggcgga ggtttcagag aaccaggcaa agcttgatga tggaaaagca
    22201 cagcttgagg atggcaagaa tcagttaagc gctggtgaga agcagattgc ggatgcaaag
    22261 acgcagctta cccagagcca gcaggaactt gacaatggaa aggcgcagat ccagtcaggc
    22321 agagagcaga ttgcagcaac cagacaggac ttaaatgcca aaaaggaaag ctgcaatcag
    22381 ggacttgccc agattgagca gcaggaggcc cagctttccg aaggagaggc tcagttagag
    22441 aatgccagaa gtcagcttgc agcattacag gcacagtatg aggaagcagc agcttcggga
    22501 gtatattcag aggaagacct ggcggctctg gcagcacagg tttccgctta tcaggagcag
    22561 gtggacagtc aggcagccca gctggaagca tccagaaacc agatcgcagc agcaagaagt
    22621 gaactggaga gtggtttaag ccaggtggag agcggactgg cccagcttga tgcaaaggaa
    22681 gcagaattga acca
//
