LOCUS       c00018_gnlPro..        25348 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HPCHFIGG_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 22:02:24
            Original ID  :: gnl|Prokka|HPCHFIGG_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 92607
            Orig. end    :: 117955
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25348
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[102607:107955]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15348
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..25348
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25348
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(54..680)
                     /locus_tag="ctg18_86"
                     /transl_table=11
                     /translation="MKIAKKFMTLALAAALGVGCATVGVGAAPSNTSDLAAVAPSKTSE
                     ITVDSEHSSIYEVVKELEKTQGFADLQAKYKDLADAFKKINAGKMKMEGFIEVLKSLSV
                     DEADKADLEDAIAKLEGKMIVTFVNEFNVLKPEEAKPNDDGTYEVKLNVPSLTDTMEGI
                     QLWVYSKDGTKKFVVIDPVNIDKEGKTLTVNLNDGDFFMVIADAK"
     CDS             complement(821..1852)
                     /locus_tag="ctg18_87"
                     /transl_table=11
                     /translation="MKKTTRKAIRQRKICMLLIIILIIVLSILGGGYYLLSQKNVASSK
                     AGGQNSDSRNQTDLNQNSDTVEYKGETYKYNDHLSNYLFLGIDTRETVDTYQSQADAGQ
                     ADAIFLVSMDRATEKIKVLFIPRDSMTRIEVFNPYGQSLGETTDHLNIQYAFGDGKEKS
                     CELMKTAVSDMLDGLPIQGYCSMNMDGISVITDFVGGIQLTIPDDSLADVNPEYKKGAV
                     VDITGETAEQFVRYRDIDKTQSALVRQERQKTFLQALVQKAQEKAGEDAGFVTGLYDSV
                     KSYTVTNMGNDIFAKLLAASQNGITDTETVPGEGTHGENFDEYHIDEDALSDLIISMFY
                     EKI"
     CDS             complement(1889..2851)
                     /locus_tag="ctg18_88"
                     /transl_table=11
                     /translation="VSKIRNKKIKKTNILLGFICILLAVLLGFILVTSYKSEQKESRHL
                     SEIADDQQSGIEDYEAVKERAKELEEISSEEAEDTEDIKSKNTEDTKDTEKTDTADTED
                     ADKTEDTKDATAAASGIVCWGDDLINGEESNTYSYMTVLQKLLTDNGYNMTVLNKTLQG
                     GGTLSMMKMAGVSDETIQSYITKHQQAANGAQLNVTETGIRDLTEEQTTRNDMDCIPVI
                     FMGYYGGWNHDPAELADQQEQILNTFQNKDQFIVVGTRPMDGSVTSEALDQVLSQKWGE
                     HYISLADVTAQPSSTYEAQQAMAEAILQKLQELNYISKN"
     CDS             complement(2915..3625)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_89"
                     /sec_met_domain="CbiA (E-value: 1.1e-07, bitscore: 26.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLNLTDKRNPDYFYSEAIKTLRTNIQLSGQSIKTILVTSCYPN
                     EGKSDIVLSLAQELGSIGKKVLLLDADIRKTAYAGRLGVEEEVKGLSQLLSGQVGLQEV
                     IYSTNFPNMDIIFGGPNAPNPSGLLSENIFKVFLKEIREYYNYILIDTPPIGTVIDAAV
                     IGRCCDGAVFLIEPGNVRYRDAQKAFKQLERSGCRILGAVMNKIDTSDDKYYSSYYKHY
                     GEYYRRSDEEAQIK"
     CDS             complement(3647..4426)
                     /locus_tag="ctg18_90"
                     /transl_table=11
                     /translation="MLDNLNSNFESSKAQRPDANDDEVEIDLLEIFYALKKKILLVLMV
                     ALVGGCIAAAYTQFLMTPIYSSTSSILVLSKETTLTSLADLQLGASLTSDYTVLITSTP
                     VMEQVISDLDLDMTAEQLKGSVSINNPTDTRILEITVNNTDSKMAKKIVDEIANVSSSY
                     IGDKMEVIPPKIIEVGKIATVRTSPSVKKNAALGFLLGFLACAAIVVVYAVMDDTIKTE
                     EDIEKYLGVSVLAKVPDRKDFINSKNRKSKNKNKKHH"
     CDS             complement(4567..5313)
                     /locus_tag="ctg18_91"
                     /transl_table=11
                     /translation="MSIKGIYDIHCHIVPGVDDGATDIGETVKLLRMEYEQGVRTVIAT
                     PHFRFRMFETPAEKVREQFRLVEKAASEISPDLHVYLGCEFHANMEMLPMLREQKVMTM
                     AGSRYVLTEFSHNSEESYIRERLGALLSGGYKPIMAHIERYETTRNSLDFVEELADMGV
                     YMQINADSITGKDGFFTKRYCNKIMKDGLLHFVGSDCHNSAKRSSRIGEAYRMVSAKFG
                     QDYADELFIHNPAEILKQKQKHEATD"
     CDS             complement(5461..6537)
                     /locus_tag="ctg18_92"
                     /transl_table=11
                     /translation="MSELSFEQMLEDSVKTIRNGEIVQGTVIDVKEDEIILNIGYKADG
                     IITKNEYSNDASLVLTDAVHVGDTMEAKVLKVNDGEGQVTLTYKRLAAEKGNKRLEEAF
                     ENQEVLKAPVTQVLDGGLCVNVDEARVFIPASLVSDTYEKDLSKYADQEIEFVITEFNP
                     RRRRIIGNRKQLLLAEKAEKQKELMEKIHVGDTVEGTVKNVTDFGAFIDLGGADGLLHI
                     SEMSWGRVENPKKVFTVGDKVKVLIKEINGEKIALSLKFPEANPWLTAAEDFAVGNVVK
                     GKVARMTDFGAFVELAPGVDALLHVSQISREHVAKPADVLSIGQEIEAKVVDFNGEDKK
                     ISLSMKALEAPAEEATEE"
     CDS             complement(6518..7396)
                     /locus_tag="ctg18_93"
                     /transl_table=11
                     /translation="MKVKVAETAGFCFGVKRAVDKVYELIDTEQKPIFTLGPIIHNEGV
                     VADLEARGVHVIAEADLDSPDDTLQNGTVVIRSHGVGKPIYDKLKEKNISYVDVTCPFV
                     LKIHRIVEKESLAGNHIIIIGDKDHPEVQGICGWCQGPYTVIRNKEEAEAFVPPKGKKI
                     SIVSQTTFNYNKFKDLVEILCKKRYDNNVLNILNILNTICNATEERQREAKNIAGEVDT
                     MLVVGGRHSSNTQKLFEICKKECGNTYYIQTPVDLDSEMFQCSSYVGITAGASTPNKII
                     EEVQEHVRIKF"
     CDS             complement(7585..8256)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytidylate_kin"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_94"
                     /sec_met_domain="Cytidylate_kin (E-value: 1.2e-76,
                     bitscore: 251.7, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGCNIAIDGPAGAGKSTIAKKVAKELSFIYVDTGAMYRAMALYLL
                     NHGVNGENQEEIEAVCSGADISIEYKNGEQIVILNGENVNAMIRTEQVGNMASKSSANP
                     KVRAHLLKLQRTLAEKNDVVMDGRDIGTTILPNAEVKIYLTASADTRAKRRALEYEQKG
                     ESFDLDQIRKDIIERDERDMNREISPLKQADDAVLVDSSEMGIDQVVDAILDVYNKKIQ
                     K"
     CDS             complement(8442..8951)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HI0933_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_95"
                     /sec_met_domain="HI0933_like (E-value: 4.2e-47, bitscore:
                     155.2, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILSASAHIGAKLAKAPNGELSAYLDLKPALTREQLDARILREFE
                     AGPNKQFKNVIGVLFPSSLTPVMLELGGIPAEKKIHDISREERQHFIDLIKAFPFTITG
                     MGEFKEAIITRGGVSVKEINPGTMESKKISGLYFAGEVLDLDAVTGGYNLQIAWSTAYL
                     AVQAIQ"
     CDS             complement(8948..9889)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HI0933_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_96"
                     /sec_met_domain="HI0933_like (E-value: 1.4e-73, bitscore:
                     242.5, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPVVHIYIDLSEAETWNYDEIDNLQGKINTGEYSMSKVIIIGGG
                     AAGMMAGVFAARNHHEVHILEKNEKLGKKVFITGKGRCNVTNACDTEELFPAMMSNPKF
                     LYSSFYSFTPQDVMEFFEKAGVPLKVERGNRVFPQSDHSSDIIRALERELKKAGAKIHL
                     HTAVQEIVKKPVTDSANTLESEATLTESGSSAGKGRKGKKSPDIPQEKITGVILTDGTF
                     MEGDAVIVATGGFSYQSTGSTGDGYRFARELGLKVTDIAPSLVPLKTKEDYVPKLQGLS
                     LKNTGLTIKNGKKVLYEDFGEMMFTHFGVTGP"
     CDS             complement(10001..10492)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: PYC_OADA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_97"
                     /sec_met_domain="PYC_OADA (E-value: 3.3e-53, bitscore:
                     174.9, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSNLTSQLKEQHAEDKFYDVLEEVPRVRKDLGEPPLVTPSSQIV
                     GTQAVFNVLMGERYKMVTKETKDILLGKYGATVKPFNPEVQKKCIGDEKPITCRPADLL
                     DNELEKLESEMAQYKEQDEDVLTYALFPQVAMDFFKYRQAQKTKVDEKAADKKNGAYPV
                     "
     CDS             complement(10477..11412)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: HMGL-like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_98"
                     /sec_met_domain="HMGL-like (E-value: 3.7e-46, bitscore:
                     152.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELEKKPVKIVETILRDAHQSQIATRMTTEQMLPIVDKLDKVGY
                     HAVECWGGATFDASLRFLHEDPWERLRKLRDGFKNTKLQMLFRGQNILGYRPYADDVVE
                     YFVQKSAANGIDIIRIFDCLNDLRNLQTAVSAANKEKAHAQVALSYTLGDAYTLEYWTD
                     IAKRIEDMGADSICIKDMAGLLLPNKATELVTALKETVKIPIDLHTHYTSGVASMTYLK
                     AVEAGVDIIDTAMSPFALGTSQPATEVMVETFKDTPYDTGFDQKLLSEIADYFRPIRDE
                     ALDSGLLNPKNLGVNIKTLLYQVPAVCSPT"
     CDS             complement(11581..12729)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_99"
                     /sec_met_domain="OAD_beta (E-value: 1.6e-155, bitscore:
                     511.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYVTETLSNLIHQTAFFSLTWGNYLMIAVACVFLYLAIKKGFEP
                     LLLVPIAFGMLLVNIYPDIMANPEDMSNGVGGLLHYFYILDEWSILPSLIFMGVGAMTD
                     FGPLIANPISFLMGAAAQLGIYAAYFLAIFLGFNGKAAAAISIIGGADGPTSIFLAGKL
                     GQSALMGPIAVAAYSYMSLVPIIQPPIMKLCTTEKERKIKMDQLRPVSKLEKILFPIVI
                     TIVVCLILPTTAPLVGMLMLGNLFRECGVVKQLTETASNALMYIVVILLGTSVGASTSA
                     EAFLNADTLKIVVLGLVAFAIGTFGGCMLGKLLCKLTHGKINPLIGSAGVSAVPMAARV
                     SQKVGAEADPTNFLLMHAMGPNVAGVIGTAVAAGTFMAIFGV"
     CDS             complement(12746..13114)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 63; E-value:
                     6e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_100"
                     /sec_met_domain="Biotin_lipoyl (E-value: 3.7e-19, bitscore:
                     63.0, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYTITVNGTAYEVTVEETGSVSAPAAAPKAAPKAAPAAAPKAA
                     APAAGAGAVKVTASVPGKVVKVAASVGQAVKAGDSVVILESMKMEIPVVAPQDGTIASI
                     DVAEGASVENGDTLATMN"
     CDS             complement(13142..13864)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_101"
                     /sec_met_domain="OAD_gamma (E-value: 2.4e-26, bitscore:
                     86.8, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFLVMAALVIGSTSVVFAADKVDDTVKSTLVTTAEGLTDAIVQL
                     KDEEIENYMSSGDDFTTSAMQSWQTSKDELGAKKESNGETTVTFKDDQYTVTVPLKFEK
                     ADANFVYVFDSQGTPTSMSVDVQYGMGKTLQRAGLNTLMGIGTVFVMLILLSLLISLFR
                     FIPNPEAKKAAEAKAAKAAKEAEAAAIAQTAPAQAEENLADDGELVAVIAAAIAAAEGT
                     TTDGFVVRSIRKVKRNRR"
     CDS             complement(13912..15348)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_102"
                     /sec_met_domain="CT_Vparvula (E-value: 4.1e-135, bitscore:
                     445.7, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNATQSLAGTRITSLLDANSFVEIGQGVTARSTDFNMTANKAPS
                     DGVITGYGVIDDKLVYVYSQDASVLNGTVGEMHAKKITRLYDLAMKTGAPVIGLVDCAG
                     IRLQEATDALEAFGQIYLKQTLASGVIPQITAIFGTCGGGMAVIPSLTDFTFMESKKGK
                     MFVNTPNALEGNNTDKCDTAAADFQSKETGVIDGVGTEDEILGQIRSLVSLLPSNNEDT
                     DNYTECTDDLNRVCADLANCAGDTAIALSQIADNGEFFETKADYAKDMVTGFIRLNGAT
                     VGAVANRSEVYDAEGKKTETFDGSISARGARKAADFVKFCDAFDIPVLTLTNATGFMAT
                     LCSEKMMAKSVGELVAAFADATVPKVNVIIGKAYGTAYVAMNSKSIGADLVYAWDNAEI
                     GMMDASLAAKIMYADADAAELNEKAAQYRELQNGVASAAARGYVDTVISPADTRKYVIG
                     AFEMLFTKREDRPSKKHGTV"
     CDS             16013..18010
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) baiH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_103"
                     /sec_met_domain="baiH (E-value: 1.9e-144, bitscore: 477.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSNYQHIFTPLTVKNMTIKNRIVMMPMGTNYGEQNGEMSFLHIN
                     YYKERAKGGTGLIIVENASVDSPQGSNGTTQLRIDHDNYLPRLYKFCEEIHKYGTCIAI
                     QINHAGASAVSARTNMQPVSASDVPSKEGGEIPRPLSVEEIHHIVKKYGEAAKRAQAAG
                     FDAVEIHAGHSYLISQFLSPLTNKRTDEFGGSVENRTRFCRMVIEEVRKQVGPSFPIML
                     RLSADELMEGGNTLEDTLEYLEYVQDEVDIFDVSCGLNGSIQYQIDANYMKDGWRSYMP
                     KAVREKFGKPCISMGNIRNPKVAEQILADGDADLIGMGRGLIAEPAWVNKVATGRECDL
                     RKCISCNIGCAGNRIGFNRPIRCTVNPAVLEGDVYKNQKVNKNCNVVVIGGGTAGLEAA
                     CTAAEVGCNTFLLEKGETLGGLASVISKIPAKKRLADFPNYLIHRAEQLENLYIFTNTE
                     GTPENIRKFHPNLIVSSTGSAPLLPPIRGLHDRIDKEGSKVASILGMINHINDYPEDMT
                     GKKVVVVGGGAVGLDVVEFFAARNAEISIVEMMDQIGRDLDPVTKNDTKDQMKKHHVAQ
                     LTKTALQEVKDSSFLVKDAEGERELPFDYGFVCLGMRAQGQLFAELSDAFVSDDIEILN
                     IGDSKRARRIIDGTLEGRNILNTLTQMGYL"
     CDS             18050..18928
                     /locus_tag="ctg18_104"
                     /transl_table=11
                     /translation="MAERITGHTELIGLMAYPIRHSSSPAMQNEAFAKLGYDYAYLAFE
                     VGADEIEDAVKAIRTLKMRGSNVSMPNKTLVGKYLDKLSPAAELCGAVNTIVNDNGHLT
                     GHITDGIGFMSALKDNDIDVIGKKMTIVGAGGAATAIEIQAALDGVAEITIFNRKDEFW
                     DRAVSTVEKINTKTSCHAVLYDLADLDKLKAEMDDSFIFVNATGVGMKPLEGQSVVPDK
                     SYFRPELIVIDVPYSPLETKMRSMAKEVGCKTMNGLGMMLFQGSAAFELWTGEPMPIEH
                     MKEILHISYDD"
     CDS             19197..19958
                     /locus_tag="ctg18_105"
                     /transl_table=11
                     /translation="MNTVQVKNTVIGEGRPKICVPIVGKTKTDILEEAKKITTLPVDVV
                     EWRVDWFDDVFATEKVLETAKELQEVLKDIPVLLTFRTSKEGGEKEISVNDYAALNIAA
                     AQSDYVDLIDVEAFTGDEVVKTIINAAHEAGVKVIASNHDFFKTPEKEEIIRRLCMMQE
                     LGADIPKIAVMPTCKQDVITLLSATLEMSEKYADRPIITMSMAGTGVVSRLTGETFGSA
                     LTFGAASKASAPGQVGVHELKQVLDIIHSSL"
     CDS             complement(20262..21503)
                     /locus_tag="ctg18_106"
                     /transl_table=11
                     /translation="MAKQKKPVHRVQMTEGKRNIIHQLLEEYDIQSAEDIQDALKDLLG
                     GTIKEMMEAEMDDHLGYEKSERSDNDDYRNGYKRKQVNSRYGSMEIEVPQDRKSTFEPQ
                     VVKKRQKDISDIDQKIISMYAKGMTTRQISETIEDIYGFETSESFISDVTDKILPQIED
                     WQNRPLDEVYPILYIDAIHYSVRDNGVIRKLAAYVILGINTEGKKEVLTISVGDNESAK
                     YWLSVMNELKNRGVKDVLIICADGLTGIKEAIAAAFPKTEYQRCIVHQVRNTLKYVPDK
                     DRKAFAADLKTIYQATDEKKALAALERVTEKWTPKYPNSMKRWKDNWDAISPIFKFSTT
                     VRTVIYTTNAIESLNSTYRKLNRQRSVFPSDTALLKALYLATFEATKKWTSTIRNWAQV
                     YGELSIMYEGRLPE"
     CDS             complement(21653..22972)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_alpha"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_107"
                     /sec_met_domain="SDH_alpha (E-value: 1.5e-59, bitscore:
                     196.3, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKVYESYLEILREELVPALGCTEPIAIAYATATAASVLEKVIK
                     TDDDGNKKYDGYLNLYCSGNIIKNVKSVTVPNSGGMRGIEAAAVLGMVGGQAERKLEVL
                     EGITEAERIQTAKLLEAQFCTCYLEEGVENLYIRAELTQNGHRAVVVIENKHTNIVLIK
                     KDDEVLLEKKGFQQKKTEKNQDKRDLLNVADILEFAKIVNIKEIEEVIGRQIAMNTAIS
                     EEGLRNHYGAEVGRTLLRAYGDDVKVRARAKAAAGSDARMNGCSMPVVINSGSGNQGMT
                     CSLPVIEYARELNVPKEKMYRALVVSNLVAIHQKNYIGSLSAYCGAVSAACGAGAAISW
                     LNGGDYNAISKTITNALANTSGIVCDGAKSSCAAKIASAVDAAIMAYALEDADHCFQAG
                     EGLVRDNVEDTIRNMGYVGRVGMKDTDVTILNLMINQKKV"
     CDS             complement(23044..23961)
                     /locus_tag="ctg18_108"
                     /transl_table=11
                     /translation="MKMFQISDKIDNVSRIGIGCMRITGLSDEKAVRSLTEGALECGIN
                     FFDHADIYAGGEAETVFGNALTPQLREKMVIQTKCAIRPGICYDFSKEYILNSVDGSLK
                     RLKTDYVDILLLHRPDALMEPEEVAEAFEILEKSGKVKAFGVSNHNPMQIELLNQYCGG
                     KICIDQIQFSAAHCPTIDAGLNVNIHNDAGCDRDGGIIEYARLKKMTLQAWSPFQYGMF
                     EGIFIGNEKFPELNKVLDRLAEKYGVTQNAIAVAWIMRHPAGIQTIVGSTNLKRIQDIS
                     KASDIVLSREEWYEIYLAAGKMLP"
ORIGIN
        1 tacaaaaaac agccgccatc tctggcgact gcgttctgat tccgaattat tgattatttc
       61 gcgtctgcga ttaccatgaa gaaatctcca tcgtttaagt taacagtaag agttttgccc
      121 tctttgtcaa tattaaccgg atcaatgact acaaacttct ttgtgccgtc tttgctgtag
      181 acccaaagct gaataccttc catagtgtct gtaagactcg gaacattaag ctttacttca
      241 tatgttccgt catcattagg ctttgcttct tctggcttca gtacgttgaa ttcattgaca
      301 aatgtaacaa tcatttttcc ttcgagttta gcaatggcat cttcaaggtc tgctttgtct
      361 gcttcatcta cggaaaggga tttcaatact tctatgaaac cttccatctt cattttacca
      421 gcattgattt ttttaaaagc atctgccaga tctttatatt ttgcctgcag atcagcaaag
      481 ccctgtgttt tctcaagttc cttaacaact tcataaattg aagaatgttc agaatccaca
      541 gtaatttcgc tcgtcttact tggcgctacc gcagccaaat cacttgtatt gcttggcgct
      601 gcaccgacac ctacagtagc acatcctact ccaagggcag ctgctaaagc aagtgtcata
      661 aatttcttcg cgattttcat aatgcacctc tccttttgga ttaattttta tatagataac
      721 cgtacagaat gtctgcacgg actatctctg aataataaca gtgataatta tttatcacag
      781 tacagtgtat tctgtattca tcatactatg actaatacaa tcagattttc tcataaaaca
      841 tggaaataat caagtccgac aatgcatctt catcgatatg gtactcatca aagttctctc
      901 catgtgttcc ctcacccggt actgtctctg tatcagtgat tccattctgt gatgcggcca
      961 gcaatttggc aaatatatca tttcccatat ttgtaactgt atagctttta acactgtcat
     1021 agagacctgt cacaaatccg gcgtcctctc ctgctttttc ctgagccttc tgcaccagtg
     1081 cctgaagaaa ggttttctgt ctctcctgac ggaccagagc actctgggtt ttgtcaatat
     1141 cacgatatct tacaaactgt tctgcagttt cccctgtaat atccacaaca gcaccttttt
     1201 tatattccgg attcacatct gcgagactgt catcagggat tgtgagctgt attccaccta
     1261 cgaaatctgt aatcactgaa atgccatcca tgttcatgga acaatacccc tggatcggaa
     1321 gtccatccag catatcggaa actgctgttt tcatcagttc acagcttttc tcttttccgt
     1381 ccccgaaggc atactgtata ttcagatgat ctgttgtctc tccaaggctc tgaccatatg
     1441 gattaaatac ttctatcctg gtcatggaat ctcgtggaat aaacagaact tttatctttt
     1501 ctgttgcacg atccatggac accaggaaaa ttgcatctgc ctgcccggca tctgcctgtg
     1561 actgataagt atctacagtt tcccttgtat caattcccag gaataaataa ttgctgagat
     1621 gatcgttata tttgtatgtc tcacctttat attccacggt atcactgttt tggttcaaat
     1681 ccgtctgatt ccggctgtca ctgttctgac cgccggcttt tgacgatgca acatttttct
     1741 ggcttaacag ataataaccg ccgccaagaa tggaaagaac tatgatcagg ataataatca
     1801 aaagcataca gatcttacgc tgtctgatgg cttttcttgt ggtttttttc attttcattc
     1861 cttcaatctc tgtatttcag ttatctcatc agtttttgct gatataatta agctcctgca
     1921 atttctgtaa tattgcctct gccattgcct gctgagcctc ataggtagaa gacggctgtg
     1981 cagtcacatc tgcaagactg atatagtgtt ctccccattt ctggctgagc acctgatcca
     2041 gtgcttcaga ggttacgctt ccgtccatag ggcgtgttcc tactacaata aactgatctt
     2101 tattctgaaa tgtatttaaa atctgttcct gctggtctgc cagttctgca ggatcatgat
     2161 tccagccgcc ataatagccc atgaagataa caggaataca atccatatca tttcttgtag
     2221 tctgttcttc tgtcagatca cgtattccgg tctctgttac attcagctgg gcaccgtttg
     2281 cagcctgctg atgtttagta atatagctct gaatagtttc atcacttaca ccagccatct
     2341 tcatcatgga gagagtgccg cctccctgaa gcgttttatt gagcactgtc atattatagc
     2401 cattatcggt cagaagcttc tgaagtactg tcatatagga atatgtattg gattcttccc
     2461 cattgatcag atcatctccc cagcacacaa tacctgaagc agctgccgtc gcatcttttg
     2521 tatcttctgt cttatctgca tcttctgtgt cagctgtatc cgttttttct gtgtcttttg
     2581 tgtcttctgt gttctttgat ttaatgtctt ctgtatcttc tgcttcttcg gaagatatct
     2641 cctccagctc ttttgcacgt tcttttactg cttcgtaatc ttcaatccca ctctgctggt
     2701 cgtccgcaat ttctgacagg tgtctggatt ccttctgttc cgatttataa ctggtcacaa
     2761 gaataaagcc caggagaact gccagcagaa tgcagataaa gcccagtaag atattcgtct
     2821 tttttatttt tttattcctt attttgctca cttttccaaa ttctccttta tcattaatca
     2881 tggtttctgt cttactgcca gataacagcc cgtattattt aatctgggct tcttcgtcac
     2941 ttctgcgata atactctcca taatgcttat aataagaaga ataatatttg tcatcactgg
     3001 tatctatctt gttcataaca gctccaagaa tacggcatcc gcttctttcc aactgtttaa
     3061 atgctttctg tgcatcccgg tacctgacat ttcccggttc gatcagaaag actgcaccat
     3121 cgcagcatct tccgatcact gccgcatcaa ttactgttcc gataggcggt gtatcgatca
     3181 ggatataatt ataatattct ctgatttcct ttaagaatac cttaaagata ttctcactga
     3241 gaagtcctga cgggttcggt gcatttggac ctccgaatat gatatccata ttcggaaagt
     3301 ttgtagaata aataacctcc tgtaatccca cctgaccgct cagaagctgt gagagacctt
     3361 tcacttcctc ttccacaccc agtcgtccgg catatgcagt cttcctgata tccgcatcca
     3421 gaaggagaac cttcttgcca atgctcccaa gctcctgggc aagactgagt actatatcac
     3481 tcttaccttc gtttggataa cagcttgtaa ccagaattgt ctttatgctc tgacccgaca
     3541 gctgaatatt ggtacgcaga gttttgatcg cctcactgta aaaataatcc ggatttcttt
     3601 tatctgttaa attgagtttc ttcattgctc agattcctcc atcagtttaa tggtgcttct
     3661 tattcttgtt ctttgatttc ctgttcttcg aatttataaa atcttttctg tcaggaacct
     3721 tggcaagaac agaaactccc aggtatttct caatatcttc ctctgtctta atagtatcat
     3781 ccattacagc gtatacaacc acgattgccg cacatgcaag gaaaccgagt aagaagccga
     3841 gtgctgcatt cttctttacg cttggagaag ttcttacagt agcaatctta ccaacttcaa
     3901 taatctttgg cggaataact tccattttat cgccaatata ggatgaagaa acattcgcaa
     3961 tctcatctac gatcttcttt gccattttag aatctgtatt attgacagta atctcaagga
     4021 tacgggtatc tgtaggatta ttgatactta cgcttccttt cagctgttct gcagtcatat
     4081 ccagatccaa atctgaaatc acctgttcca tcacaggggt acttgtgatc agaactgtat
     4141 aatcactggt caggctggca cctaactgca gatccgccag tgatgtcagt gtggtttctt
     4201 tcgaaagtac aaggatactg gatgtggagc tgtagatcgg tgtcattaaa aactgcgtat
     4261 atgctgctgc aatacagcct ccgacaagag caaccatcag taccagaagg atttttttct
     4321 tgagcgcata aaatatttcc agtaagtcga tttcgacttc atcatcattt gcatcgggtc
     4381 tctgtgcttt gctgctctca aagttactgt tcaaattgtc taacatctga taatttcctt
     4441 ttcccttttt tctttatagt tttgtacatt actgttcaca ggtaatattc tgtcttatgt
     4501 atttctgaaa gtaaacagca aaattgacat aaaccgattt tattgtatat cagccaataa
     4561 aaaaagtcaa tctgtagcct catgtttttg tttctgtttc agaatttctg caggattatg
     4621 aataaacagt tcatctgcat agtcctgccc gaatttcgct gaaaccatac gatatgcctc
     4681 tccaatcctg ctgctcctct ttgcactgtt gtgacagtct gatccaacga aatgaagaag
     4741 tccgtctttc atgattttat tacagtaccg tttagtaaaa aatccgtctt ttcctgtgat
     4801 gctgtctgca ttgatctgca tatagacacc catatctgcc agttcttcca caaaatccag
     4861 actgttgcgt gtggtttcgt aacgttctat atgtgccatg atcggcttat atcctccgga
     4921 gagcaatgca ccgagacgtt cccgtatata gctttcttcc gagttatggg aaaattctgt
     4981 aagaacatac cgcgaaccgg ccattgtcat tactttctgt tctctgagca tgggaagcat
     5041 ctccatattg gcgtgaaact cacatcccag atacacatgg agatccgggc tgatctctga
     5101 tgccgctttc tccaccagtc tgaactgctc tctgactttc tccgcaggtg tttcaaacat
     5161 ccgaaagcgg aaatggggag ttgcaataac cgtccgcaca ccctgttcat attccatccg
     5221 gagtaatttt acggtttctc ctatatctgt ggctccatcg tctacaccgg gtacaatatg
     5281 acagtgtata tcataaattc cttttatgga catcctataa ttccttcctg actgtctgca
     5341 gcatttctga tgctcctgta gctgctgacc acattcgtaa tctgaaaaaa caatcaaccg
     5401 gctctgtatg atcatcctca tacaaagccg gtttctgaat atttatgagt attctcttga
     5461 ttattcttct gtagcttcct cagccggtgc ctcaagagct ttcatgctca ggctgatctt
     5521 cttgtcttcg ccgttgaagt caacaacctt agcttctatc tcctgtccga ttgacagtac
     5581 gtctgcaggt ttggcaacat gctctctgga aatctgggat acgtgaagaa gtgcatctac
     5641 accaggtgca agctctacga atgcaccgaa gtctgtcata cgtgcaactt tacctttaac
     5701 tacgtttcct acagcgaagt cctcagctgc tgtgagccat ggatttgctt ccgggaattt
     5761 aagggaaagt gcgatcttct ctccgttgat ctctttgata agaactttaa ctttatcgcc
     5821 aacagtgaat actttcttcg ggttctctac tctgccccag gacatttcgg agatgtgaag
     5881 aagtccgtct gctccgccaa gatcgatgaa tgcaccgaaa tctgtaacgt tcttaactgt
     5941 tccttcaact gtgtcgccaa catggatctt ctccattaat tctttctgtt tctctgcttt
     6001 ctcagcaaga agaagctgct tacggttacc gatgatgcgg cgtcttctcg ggttgaattc
     6061 tgtgataacg aattcgatct cctgatctgc atatttggaa aggtctttct cgtatgtgtc
     6121 ggaaacgagg cttgcaggaa tgaatactct tgcttcgtct acgtttacac agagtccgcc
     6181 gtcaagtacc tgagttacag gagcttttaa tacttcctga ttctcaaatg cttcttcaag
     6241 acgtttgttg cctttctctg ctgccagtct cttgtaagta agagtaacct gaccttctcc
     6301 atcgtttact ttgagaactt ttgcttccat tgtgtctcca acgtgaacag catctgtgag
     6361 tacaaggctt gcatcgttag agtattcgtt ctttgtgata ataccgtctg ctttataacc
     6421 gatattcaga ataatctcat cttcttttac atcgatgaca gtaccctgta caatctctcc
     6481 atttctgata gtctttacgg aatcttccag catctgttca aaacttaatt ctgacatgtt
     6541 cttgaacctc ctcaataatt ttgtttgggg tggaagcccc tgctgtaata cctacataac
     6601 tactgcattg gaacatttca gaatccaagt ctacaggtgt ttgtatatag taagtatttc
     6661 cacattcctt tttacatatt tcaaacagct tttgagtatt ggaactgtgc cgaccgccta
     6721 cgaccagcat agtgtctacc tctccggcta tgttttttgc ttctctctgc cgttcttcgg
     6781 tagcattaca aatagtgttt aaaatattga gaatatttaa aacattatta tcatacctct
     6841 ttttgcaaag aatttcaact aaatctttaa atttgttgta attaaatgtc gtctgggaca
     6901 caatacttat ttttttgcct tttgggggta caaatgcttc ggcttcttct ttgtttctga
     6961 tcaccgtgta cggcccctga caccagccgc agatgccctg tacttcgggg tggtctttgt
     7021 cgccgatgat gatgatgtgg tttcctgcaa ggctttcttt ttccacgatc ctgtggattt
     7081 tcaggacgaa ggggcaggtc acatctacat aagagatgtt tttttctttc agcttatcgt
     7141 agatgggttt acctacgccg tgagagcgga tgactactgt tccgttctgc agggtgtcat
     7201 ccggggaatc caggtctgct tctgcgataa catggacgcc acgggcttcc agatccgcta
     7261 ctacgccttc attgtggatg atcggaccca gagtgaagat tggtttctgt tctgtgtcga
     7321 tcagctcgta gactttgtcc actgcacgtt tgacgccgaa gcagaagcct gctgtctctg
     7381 ctactttaac tttcataaat aaatcctttc cttacccgta aaagaatgtt tgctgtatag
     7441 catgggaagt ttacagttac agatgagtat atcttgtctg taaagggtgc tgtcaaccac
     7501 cctatgatgc agcaccattt taggtgatag gtagttgacg ggcaaatagc gtagtctgaa
     7561 acagataatc tgtccgcctg accgttattt ctgtatcttc ttattataca catcaagaat
     7621 agcatctaca acctgatcaa ttcccatttc cgaggaatct acgagcactg cgtcgtctgc
     7681 ctgtttcaga ggggagattt cgcggttcat gtcgcgttcg tcgcgctcga tgatgtcttt
     7741 tcggatctgg tccaggtcga aggattctcc cttctgttca tattccagtg ctcttctttt
     7801 tgctctggtg tctgcgcttg ctgtgaggta gatttttact tctgcgtttg gaaggatggt
     7861 tgtgccgata tctctgccgt ccatgactac gtcgtttttc tctgccagag ttctctgaag
     7921 tttcagaagg tgggctctga ctttcgggtt tgcggagctt ttggatgcca tgtttcctac
     7981 ctgttcagtg cggatcatag catttacgtt ctctccgttg aggataacaa tctgttctcc
     8041 gtttttgtat tcgatggaga tgtcagcgcc ggaacatacg gcttcgatct cttcctgatt
     8101 ttctccgttt acgccatgat tcaaaagata taaagccatt gccctgtaca tggctcctgt
     8161 atctacatag ataaatgata attctttcgc tactttcttt gcgatggtgc tctttcctgc
     8221 tcctgcaggt ccgtcgatgg ctatgttaca tcccattttc gtggttcctc ctgtttctat
     8281 tattcaaaca aattttctct gttttattat taatgtttat taatcagtca agcagatatt
     8341 ctcaatccgc ttcgctactt gctcataacc gaatcataga tataattcgc atacacggta
     8401 ctcatcatct gcttgtttct gttgtttcta tagtaagcag cttactgtat ggcctgtact
     8461 gccagatatg cggtagacca ggcaatctgt aagttatatc cacctgtcac tgcatccaga
     8521 tccagtacct cgcctgcgaa gtaaagacct gagattttct ttgattccat tgttccggga
     8581 ttgatctctt tgacagagac gccgcctctg gtgatgatgg cttctttgaa ctcacccatt
     8641 cctgtgattg tgaaggggaa ggctttgata aggtcaatga agtgctggcg ttcttctctg
     8701 gagatgtcgt ggattttctt ctctgcgggg attccaccca gttccagcat taccggagtc
     8761 agagatgacg ggaaaagtac gccgatcacg ttcttgaact gtttgtttgg tcctgcttca
     8821 aattcacgca ggatcctggc atccagttgt tctctggtga gtgcaggctt cagatccaga
     8881 tatgcggaca gttcgccgtt tggtgctttt gccagttttg caccgatgtg ggcactggcg
     8941 gagaggatca tgggcctgtg actccgaaat gggtgaacat catctctccg aaatcctcat
     9001 agagtacttt ctttccattc tttatggtga gtcctgtgtt cttaagggaa agtccctgaa
     9061 gcttagggac atagtcttct tttgtcttta atggcacaag ggagggagca atgtccgtga
     9121 ctttcagtcc cagttctctt gcgaagcggt atccgtcacc tgtggagcct gtactctgat
     9181 aagagaatcc accggttgcc acgatgactg catctccttc catgaaggtt ccatctgtaa
     9241 ggatgactcc tgtgatcttc tcctgcggta tgtcaggtga tttttttcct tttctgcctt
     9301 ttcctgcact agatcctgat tctgttaatg tagcttctga ttccagggta tttgccgaat
     9361 ctgttacagg tttctttacg atttcctgca cagcagtgtg aagatgaatc tttgctcctg
     9421 ctttcttcag ctcacgctcc agagcgcgga tgatgtctga agaatggtca gactgtggga
     9481 atactctgtt tccacgctct accttcagag ggacacctgc tttctcaaag aactccatta
     9541 catcctgagg ggtaaatgaa tagaaactgc tgtagaggaa cttgggattg ctcatcattg
     9601 caggaaagag ttcttctgtg tcgcaggcat ttgtcacatt gcatctgcct tttcctgtga
     9661 tgaagacttt ctttcccagt ttctcgttct tctctaatat atgaacttca tgatgattac
     9721 gggctgcaaa aacccctgcc atcattccgg cggctccgcc gccgattatt ataactttgc
     9781 tcatggaata ttctcctgta tttattttac cctgcagatt gtctatttca tcatagttcc
     9841 acgtttccgc ttcactaaga tcaatataga tatgtaccac tggcagcata tacccattgg
     9901 cacattatat tcccgggtat catattcttt cataataacg caaaggagcc tgcttacgca
     9961 agctcctttt ttcgtttgga catatttaat tactgatcaa ttatacagga tatgctccgt
    10021 tctttttgtc agctgctttc tcgtcaactt ttgttttctg agcctgacgg tatttgaaga
    10081 agtccatagc tacctgtggg aacagtgcgt atgttaatac gtcttcatcc tgttccttat
    10141 actgagccat ttcgctctca agtttctcaa gctcgttgtc aagaaggtct gcaggacggc
    10201 atgtgatcgg tttctcatcg ccgatgcact tcttctgtac ttccggatta aacggtttta
    10261 cagttgcgcc gtattttcct aacaggatat cttttgtttc ttttgtaacc attttgtatc
    10321 tctcgcccat aagtacgttg aatacagcct gtgtaccaac gatctgtgaa gacggagtaa
    10381 caagtggcgg ttcaccaagg tctttacgta cacgcggaac ttcctcgaga acatcgtaga
    10441 atttgtcttc tgcgtgctgt tcttttaact gggaagtcag gttggagagc ataccgccgg
    10501 tacctggtac agtaaagtct tgatgttaac accaaggttc ttcggattga gcagtccgct
    10561 gtcaagagct tcgtcacgga tcggacggaa gtagtcagcg atctcggaga gaagcttctg
    10621 atcaaatcct gtgtcgtatg gtgtatcctt gaatgtctca accataacct ctgttgcagg
    10681 ctgggatgtt cccagtgcaa atggagacat tgctgtatca atgatatcca cacctgcttc
    10741 tactgctttt aagtaagtca tggaagctac acctgaggtg taatgtgtat gaaggtcgat
    10801 cgggatctta actgtttctt ttaatgctgt tacaagctct gtagctttgt ttggaaggag
    10861 aagacctgcc atatctttga tacagatgga atcagcgccc atatcttcaa tacgttttgc
    10921 aatgtctgtc cagtattcca gtgtgtaagc atctcctaat gtgtaggaaa gagctacctg
    10981 tgcatgagcc ttctctttgt ttgcagcgct tactgctgtc tgcaggttac gaaggtcatt
    11041 gaggcagtca aaaatacgga tgatgtcgat tccgtttgca gcagatttct gtacgaagta
    11101 ttctacaacg tcatctgcat atggacggta tccaaggatg ttctgtccac ggaaaagcat
    11161 ctgaagtttt gtgtttttga agccgtcacg taatttacga agtctttccc atggatcttc
    11221 atgaaggaaa cgaagggatg catcgaatgt tgcaccaccc cagcactcta ctgcgtgata
    11281 gccgacttta tcaagtttat ctacgatcgg aagcatctgt tctgtggtca tacgtgttgc
    11341 gatctgggac tgatgagcat cacggagaat ggtttccaca attttaacag gttttttctc
    11401 taattctgcc attattaaat ctcctttata gtttgttcgt tactgatcat tttgttctca
    11461 ataactcagc caatattact tcagggttca gacagttgtc ataccctgtg gctctatatc
    11521 gaatagctgt tccactgctt attgcatccg caataaaagc agggaactca tttcattcaa
    11581 ttatacaccg aaaatagcca tgaatgttcc ggctgctacg gctgtaccga taacaccggc
    11641 aacgttcggg cccattgcgt gcatcagaag gaagtttgta ggatctgcct ctgcacccac
    11701 tttctgggat acacgggctg ccataggtac tgcggataca cctgcggaac cgatcagcgg
    11761 gttgatcttt ccatgagtca gtttgcagag cagtttacca agcatacatc cgccgaatgt
    11821 accgattgcg aatgcaacaa gacctaaaac tacgatcttc agagtatctg cgtttaagaa
    11881 tgcttctgca cttgtggaag cacctacgga tgtacccaga aggataacta cgatatacat
    11941 cagggcattg gaagctgttt ctgtcagctg ttttacaaca ccgcactctc tgaacaggtt
    12001 accaagcatg agcataccaa ccagcggagc tgttgtaggc aaaatcaggc agacaacgat
    12061 tgtgataacg atcgggaaca ggatcttctc cagtttggaa accgggcgaa gctgatccat
    12121 tttgatctta cgttctttct ctgttgtgca gagtttcatg ataggcggct ggatgatcgg
    12181 aaccagtgac atataggaat atgctgccac tgcgatcggt cccatcagtg cagactgtcc
    12241 aagtttacct gcaaggaaaa tggaagtcgg gccatcagca ccaccgatga tggagatagc
    12301 tgccgctgct tttccgttga atccaaggaa gattgcaagg aagtaagctg catagatacc
    12361 aagctgtgct gcagcaccca tcaggaagct gatcgggttt gcaatcagcg gaccgaagtc
    12421 tgtcatggca cctacaccca tgaagatcag ggatggtaag atactccact catcaaggat
    12481 gtagaaataa tgaagaagtc cacctacacc attagacata tcttccgggt ttgccataat
    12541 gtccggatag atatttacaa gcagcatacc gaatgcgata ggaacaagca gaagcggctc
    12601 gaatcccttc ttgatagcaa ggtaaaggaa tacgcaggct actgcgatca tcaggtaatt
    12661 gccccatgtc aaactgaaga atgctgtctg atgaatcagg ttggacaatg tttctgttac
    12721 ataagacatt tgactacctc ccgtcttagt tcattgttgc taaagtatct ccgttttcta
    12781 cagaggcacc ttctgcaaca tcaatgcttg cgatagtacc atcctgagga gctactacag
    12841 ggatttccat tttcatggat tcaagaataa ctacgctgtc tccggctttt actgcctgtc
    12901 caacgcttgc tgctactttg acaactttgc caggtacgga agcagttact tttactgcgc
    12961 cggcgcctgc tgcaggagct gctgctttcg gagctgctgc aggtgcagcc ttaggtgctg
    13021 cttttggagc tgctgcagga gcggatacgc ttcctgtttc ttcaacagtt acttcatatg
    13081 ctgtaccatt tactgtaatt gtatagcttt tcattttaaa atcctcctaa ataaatgaca
    13141 attatcttct atttcttttt actttacgga tggaacgaac tacgaagccg tctgttgtag
    13201 ttccttctgc tgctgcgatg gctgctgcga taacagctac cagctctccg tcatctgcaa
    13261 ggttctcttc tgcctgtgca ggtgctgtct gtgcgatggc tgctgcctct gcctcttttg
    13321 cagctttggc tgcttttgct tctgctgctt tctttgcttc cggattcgga ataaatctga
    13381 acagagaaat cagaaggctt aataaaatca gcattacgaa tacagttcca atacccatca
    13441 aagtattaag gcctgctctc tgaagagtct tgcccatacc atactgtaca tctacagaca
    13501 tggaagtcgg tgttccctgt gagtcaaaga catatacaaa gtttgcatct gctttctcaa
    13561 atttaagagg aacagtaact gtgtactgat catctttgaa agttacagtg gtttcaccat
    13621 tgctttcctt ctttgcgcca agttcatcct tggatgtctg ccaggactgc atggcacttg
    13681 ttgtaaagtc atctcctgaa ctcatgtaat tctcgatttc ttcatcttta agctggacaa
    13741 tggcatctgt cagtccttct gctgtagtta ccagtgtgga cttaacagta tcatcaacct
    13801 tatctgcggc aaataccaca gaggtgctgc caatcaccag cgcagccatt acgagaaatg
    13861 tcatgaatac agaagttatt tttttgatca ttttcatatg cgtcaccccg cttagaccgt
    13921 tccatgtttc ttagacggac gatcttctct ctttgtgaac agcatctcaa atgcaccgat
    13981 tacatatttt cttgtgtcag ccgggctgat cacagtgtca acatagcctc ttgctgctgc
    14041 ggaagcaaca ccattctgaa gctctctgta ctgagcagct ttttcattca gttcagcagc
    14101 atctgcatct gcgtacatga tcttggctgc cagggaagca tccatcatac cgatctctgc
    14161 gttatcccat gcatatacaa ggtctgcacc gatagatttg ctgttcattg ccacgtaagc
    14221 tgtaccgtaa gctttgccga tgatcacatt taccttcgga acagttgcat ctgcgaatgc
    14281 agctaccagt tcacctacgg atttcgccat catcttctcg ctgcataagg ttgccatgaa
    14341 gcctgttgcg tttgtaagtg taagtaccgg aatatcaaaa gcgtcgcaga atttcacgaa
    14401 atctgctgct tttcttgcgc ctcttgcaga gatgcttccg tcaaatgttt ctgttttctt
    14461 gccttctgcg tcatatactt cgcttctgtt tgcaacagca cctactgtag cgccgtttaa
    14521 acggataaag cctgtaacca tgtcttttgc atagtctgct tttgtctcga agaattcacc
    14581 gttgtcagcg atctgggaaa gtgcgattgc tgtgtcacct gcacagtttg caagatctgc
    14641 gcatacgcgg ttaagatcgt ctgtacactc tgtgtaattg tctgtgtctt cattattaga
    14701 aggaagaagt gatactaagg aacggatctg gccaagaatc tcatcctctg taccaacgcc
    14761 atcgatcaca cctgtctctt tgctctggaa atcagctgct gctgtgtcgc atttgtctgt
    14821 gttgtttcct tccagtgcgt ttggtgtgtt gacgaacatt tttccttttt tggattccat
    14881 gaatgtgaaa tctgtcaggg acgggataac tgccatacca ccgccgcatg ttccgaagat
    14941 tgctgtgatc tgcgggatca caccggatgc caatgtctgt ttcagataga tctgtccgaa
    15001 agcttccagt gcgtctgttg cttcctgaag acggatacct gcacagtcaa caagtccgat
    15061 aaccggagcg cctgttttca tggcaagatc ataaagtctt gtgatcttct ttgcatgcat
    15121 ttcaccaaca gtaccgttta atacagatgc atcctggctg tatacataaa ccagtttgtc
    15181 atcgatcaca ccatatccgg tgataacacc gtcagatggt gccttgtttg cagtcatgtt
    15241 gaaatctgtg gatctggctg ttacaccctg tccgatttcg acaaaactgt ttgcgtcaag
    15301 caaagaagta attcttgtgc ctgctaagct ttgtgttgca ttactcattc ttgtttgccc
    15361 tccatcttta tgagaatatt taaaagttaa cccaaaaatt tagccgattt taattttacc
    15421 tttttcagca gaaaatttca acatttattt gtcattttcg ttaaaaatat agcagaaaaa
    15481 tttgtcaggt ttctccaaat tttgtttttt tgagcatttc ttcctatttt aatagagggt
    15541 attacggtta ttttgtattg tcctgtattt caccctctcc cgcaaaccag tgtgtcgaca
    15601 agttgatttc tcgaacaatc ctgcgtctga atttcttatt tctatcctgc aagattgttt
    15661 caagaatcaa cttgtcggca caccagagcg tgtttgaggt gactatacca ctcacttgtc
    15721 tgagaatccg actgcacaag tataaaagtc tcagcgcagc tcggtgaaaa aatgctatag
    15781 tcatacaggt tcagcaggat tttcccatgc tgtggatgca gttgcgaatg ctttcattca
    15841 gtacgcggac agtgcacgga aaaccataga tgttttttat tatatagcac gaattatcaa
    15901 ttagatttac ggattatccc attatataat taacacatca aagaaattca ggccacagct
    15961 aaagcactga acagctatag atacaacaga aaatttcagg aggaaagacg taatgaaaag
    16021 caattaccag catattttca caccactcac agtaaaaaat atgactatca aaaaccgtat
    16081 cgttatgatg cctatgggaa ccaattacgg ggaacagaac ggcgaaatga gttttcttca
    16141 cattaattat tataaagagc gtgccaaagg cggcacaggt ctgatcatcg tagagaatgc
    16201 aagcgtagat tctccgcagg gttccaacgg aactactcag cttcgtattg accacgacaa
    16261 ctatctgccg cgtctgtaca aattctgtga agagatccac aaatatggta cctgtattgc
    16321 gatccagatc aaccacgcag gtgcttccgc tgtttccgca cgtacaaata tgcagccggt
    16381 ttccgcatct gatgttccgt ccaaagaagg cggagagatc ccgcgtccgt tatcagtgga
    16441 agaaatccat cacattgtaa agaaatacgg cgaggctgca aaaagagccc aggctgcagg
    16501 ttttgacgca gtagagatcc atgcgggaca ttcctatctg atcagccagt tcctctctcc
    16561 tcttacaaac aaacgtacag atgagttcgg cggatctgtg gaaaacagaa cacgtttctg
    16621 ccgtatggtc attgaagaag taagaaaaca ggtcggacct tccttcccga tcatgctccg
    16681 tctcagcgca gatgagctga tggaaggcgg caacactctt gaggatactc ttgaatatct
    16741 ggaatatgtt caggatgaag ttgatatctt cgatgtttcc tgcggtttaa acggttctat
    16801 ccagtatcag atcgatgcca actacatgaa agacggatgg cgttcctata tgcctaaagc
    16861 tgtcagagag aaattcggca agccatgtat ctccatggga aatatccgta acccgaaggt
    16921 tgctgagcag atcctcgctg acggcgatgc agacctgatc ggtatgggac gtggtcttat
    16981 cgcagaacct gcatgggtga acaaagtagc tacaggcaga gaatgtgacc ttcgcaaatg
    17041 tatctcctgt aacatcggat gtgcaggaaa cagaatcggc tttaaccgtc cgatccgctg
    17101 tactgtaaac ccggctgttc tggaaggtga tgtttataag aatcagaaag tgaacaaaaa
    17161 ctgtaatgtt gtagtaatcg gaggcggtac tgccggactg gaagctgcct gtacagccgc
    17221 agaagtaggc tgtaatacct tcctcctgga aaaaggtgag actcttggcg gtcttgcttc
    17281 tgtgatctct aagattcctg caaagaagcg tctggctgat ttcccgaact atctgattca
    17341 cagagcagag cagcttgaga atctttatat cttcacaaac acagaaggaa caccggaaaa
    17401 tatccgcaag ttccatccga acctgatcgt aagctccaca ggttccgcac cactgcttcc
    17461 tccgatcagg ggacttcacg accgcattga caaagaaggc agcaaggttg cttctatcct
    17521 gggaatgatc aatcacatca atgactatcc ggaagatatg acaggcaaga aggttgttgt
    17581 tgtgggcggc ggtgctgttg gtcttgatgt tgtggaattc tttgcagcaa gaaatgctga
    17641 aatctctatt gtggagatga tggatcagat cggacgtgac ctggatcctg ttacaaagaa
    17701 tgacacgaag gaccagatga agaaacatca tgtggcccag cttacaaaga cagctcttca
    17761 ggaagtaaaa gacagctctt tccttgtaaa agatgcagaa ggtgaacgtg agcttccatt
    17821 tgactacgga ttcgtatgtc ttggtatgag agctcaggga cagcttttcg cagagctttc
    17881 cgatgctttt gtttctgatg atattgagat cctgaacatc ggagacagca aacgtgcaag
    17941 aaggatcatc gacggaactc tggaaggaag aaatatcctt aatacactga ctcagatggg
    18001 atacctttaa taaaaacctt tacaacaaaa tacgaaaggg gatattataa tggctgaaag
    18061 aattaccgga catactgaat taatcggtct gatggcttac ccgatccgtc actccagctc
    18121 tcctgcaatg cagaatgagg cttttgcaaa actcgggtat gactacgctt accttgcttt
    18181 cgaagttggc gcagatgaaa ttgaggatgc agtaaaagca atccgtactc tgaaaatgag
    18241 aggatccaat gtttccatgc caaacaaaac tctggttgga aaatacctgg ataagctttc
    18301 tcctgcagca gaattatgcg gtgcagttaa cacgatcgta aatgacaacg gtcatcttac
    18361 aggtcatatc actgacggta tcggatttat gtctgccctg aaagataatg atattgatgt
    18421 gatcggaaag aaaatgacta tcgtcggtgc aggcggtgct gccactgcta tcgagatcca
    18481 ggctgctttg gacggcgttg ccgagatcac aatctttaac cgcaaggatg aattctggga
    18541 tcgtgcagta tccacagtag agaagatcaa cacaaagaca tcctgccatg cagttcttta
    18601 tgatctggca gatcttgata aactgaaagc tgagatggat gacagtttta tctttgtcaa
    18661 tgctacaggt gtgggaatga aaccactgga aggccagtcc gttgttccgg acaagtctta
    18721 cttccgtcct gagctgatcg ttattgatgt tccttactct cctctggaaa caaaaatgcg
    18781 ttccatggcc aaggaagttg gatgtaagac aatgaatggt ctgggaatga tgttattcca
    18841 gggttccgct gcatttgagt tatggacagg cgaaccaatg cctatcgaac atatgaaaga
    18901 gattcttcac atctcctatg atgactgata cctgatggta tcttcagtaa agatatctca
    18961 tattgtgatg cagaacagat catttcactg atctttctgc acataatatt tgatatatac
    19021 cgcttttcgg cgtactgcag gagatgtact gatatattac tccgcgcaga atgtacatat
    19081 cctgcagttt gcttcaaaaa gctgttgatc atgcggttat gttacggtta ttcttataac
    19141 agttccataa taatccggaa ctactataat acaacagaaa atatgaggat aaacagatga
    19201 acacagttca ggtaaaaaac actgtgatcg gcgagggcag acctaagatc tgcgttccca
    19261 tcgtaggaaa aacaaaaaca gacattctcg aagaagcaaa aaaaatcact actcttcctg
    19321 ttgatgtagt tgagtggcgt gtagactggt ttgatgatgt ctttgctact gagaaagtat
    19381 tagaaaccgc taaagagctt caggaagttt taaaagacat tcctgttctc cttacattcc
    19441 gtacttccaa agaaggcggt gagaaagaaa tttctgtaaa tgactatgct gctttaaata
    19501 ttgcagctgc tcagagcgat tatgtagatt taattgatgt agaagcattt acaggtgatg
    19561 aagttgttaa gacaatcatc aatgctgctc atgaggcagg tgtaaaggta attgcttcca
    19621 accatgattt ctttaagact ccggagaagg aggagatcat cagacgcctc tgcatgatgc
    19681 aggagctggg tgctgatatc cctaagattg cagtaatgcc tacctgtaag caggatgtta
    19741 tcacactgct gtctgccact ctggaaatgt ctgagaaata tgcagaccgc ccaatcatta
    19801 ccatgtccat ggcaggaaca ggcgttgtaa gccgtctgac aggtgagaca ttcggctccg
    19861 ctctcacttt cggtgctgct tccaaagctt ctgctccggg acaggtcggt gtgcatgaat
    19921 taaaacaggt gctggatatc attcacagca gcctgtgatc tgttgatgaa tgatgtgata
    19981 tcagatgtta ttcttgccca tagttgtctg atatcactca tcttcggcaa cagatgattg
    20041 ttatcccatg agatatatgg caataaatat ttactcaaaa atactcctta aaattttatg
    20101 agagactatg agaaaaagtc tgtaaataag attcttctat gatatgcaag ggtggcaagc
    20161 ctgaaaatca ggcttctcac ccttgtttta tatataacag ttgttgaatg gcatgtcaag
    20221 agcaggcggt tttccgcccg tcttattcgc ccgtttattc gttactctgg gaggcgtcct
    20281 tcgtacataa tactcagttc accatacacc tgtgcccagt tgcggatcgt actggtccat
    20341 ttctttgtag cttcaaatgt ggcaagatac agtgccttta atagagctgt atcgcttgga
    20401 aatacgcttc tctggcgatt cagtttccgg taggtagaat tcagggattc aatagcattt
    20461 gtagtataaa tcactgttct gaccgtcgtt gaaaatttaa agatcggcga gattgcgtcc
    20521 cagttatcct tccagcgctt catggaattc ggatatttcg gtgtccattt ttctgttaca
    20581 cgctctaagg ctgccagagc tttcttttca tctgtggcct gataaatggt tttcagatcc
    20641 gcagcgaagg cttttctgtc tttatccggg acatatttca acgtgttcct tacctggtgt
    20701 acaatacagc gctggtattc cgtctttgga aaagctgctg cgatcgcttc tttgattccg
    20761 gttaaaccat cggcacagat gattaataca tctttgacac cacggttttt cagttcattc
    20821 ataacggaaa gccagtattt tgcgctttcg ttatcgccaa cactgatggt taaaacttct
    20881 ttttttcctt ccgtgttgat tcccagaatc acgtaagcag caagctttcg gatcacgcca
    20941 ttatccctta cagaataatg gattgcatca atgtagagaa tgggatagac ctcgtccagt
    21001 ggccggttct gccagtcttc gatctgtggc aggatcttat cagtcacatc agaaataaag
    21061 ctttcagaag tttcaaagcc ataaatatct tcgatggttt cggaaatctg ccgggtagtc
    21121 attcctttgg catacatgga aatgatcttc tgatcaatat cggaaatatc tttctgacgt
    21181 tttttcacaa cttgtggttc aaacgttgat ttgcgatcct gtggcacttc gatttccatc
    21241 gagccatacc ggctgttgac ctgtttccgc ttataaccat tgcgataatc atcattatct
    21301 gagcgttcgg atttttcgta accaagatga tcatccattt cagcttccat catttcctta
    21361 atggtgccgc ctaaaagatc cttgagcgca tcctgaatgt cttctgcaga ctggatatcg
    21421 tactcttcca ggagctgatg gatgatgttt cgttttcctt ctgtcatttg tacacgatgt
    21481 acaggtttct tttgttttgc cataataaaa ggccctccta atgatattta ttgtatcata
    21541 gaagaacctt ataaacatta ttttacagaa aaagtttcat actctctttt atgatgaaaa
    21601 ttcccatgac aaagaacctg ccaaaaacct gacaggttct ttgtttttat ttttatactt
    21661 ttttctgatt gatcatcaaa ttcaggattg taacatctgt atctttcatt ccaactcttc
    21721 ctacgtatcc catatttcgg attgtatcct caacattatc acgtaccaat ccttctcctg
    21781 cctgaaaaca atgatctgca tcctccagag cgtatgccat aattgctgca tctactgctg
    21841 aagcgatttt ggcagcacat gaagacttag ctccatcaca tacaatgcca cttgtatttg
    21901 caagagcatt tgtgattgtt ttagatattg cattgtaatc accaccgttt aaccaggata
    21961 tggcagctcc tgctccacat gcggcactta ccgctccaca gtaagctgac agacttccaa
    22021 tataattttt ctgatgaatc gctactaagt tgcttacaac cagtgcacga tacattttct
    22081 ctttaggaac gttaagttct ctggcatatt caatgactgg caaagaacag gtcattccct
    22141 gatttccgct cccggaatta ataactaccg gcatagagca tccattcatt cttgcatcag
    22201 atccagctgc cgccttcgct ctggcacgta ctttgacatc atcaccatat gctcgaagca
    22261 gggtacgtcc gacttctgct ccgtaatgat tacgcaggcc ttcttcggaa attgctgtat
    22321 tcatggcaat ctggcgtcct atgacttcct ctatctcttt tatattcaca atttttgcaa
    22381 actccagaat atctgctaca ttcagcaaat ctcttttatc ctggtttttc tctgtttttt
    22441 tctgctgaaa gcccttcttt tccaacagta cctcatcgtc ttttttgatc aggacaatat
    22501 tcgtatgttt attttctata actacaactg ctctatgtcc attttgcgta agttctgcac
    22561 ggatataaag attctctact ccttcttcaa gataacatgt gcagaattgt gcttccagaa
    22621 gttttgccgt ctgaatgcgt tcagcttctg taattccctc cagtacttcc agtttccgtt
    22681 ctgcctgacc accaaccatt ccaagaactg cagcagcttc aatgcccctc attcctcctg
    22741 aatttggtac tgtaacactt tttacatttt ttattatatt tccactgcaa taaagattta
    22801 aatatccatc atatttttta tttccatcat catctgtttt tatcactttt tccagcacag
    22861 aagctgctgt tgcagttgca tatgcaattg caataggttc cgtacatccc agagcaggaa
    22921 caagttcttc tctgagaatc tccagataac tctcatacac ttttttttcc atgaatacgc
    22981 tctctcttct cctaactgtc aagcaaagtt ctttaccatc tgattcagat gatatgtttt
    23041 ttcttacggc agcatttttc ctgctgcaag ataaatttca taccattctt cacggctcag
    23101 aacaatatcg gatgctttac ttatatcctg aattcttttc agatttgtac ttcctacaat
    23161 tgtctggatt cctgcgggat gacgcataat ccatgcaact gcgattgcat tctgtgttac
    23221 cccatatttc tctgccagac gatctaacac tttattcagt tccggaaatt tctcgtttcc
    23281 aataaatatt ccctcaaaca ttccatactg gaacggagac catgcctgca atgtcatttt
    23341 cttcagtctt gcatactcga taataccacc atcacgatca catcctgcat cattatggat
    23401 gtttacattt agtcctgcat caatcgttgg acagtgagcc gctgaaaact gtatctgatc
    23461 aatacagatt tttccaccac agtattgatt tagtaattcg atctgcatcg gattgtgatt
    23521 gcttacacca aatgctttta cttttccgct tttttccaga atttcaaatg cttctgctac
    23581 ctcttccggc tccatcaacg catccggacg atgaagaagt aatatatcta cataatctgt
    23641 ttttaaacgt ttcagacttc catctacaga attcagaata tattcttttg aaaaatcata
    23701 acagataccc ggacgtatgg cacattttgt ctgaatcacc atcttttcac gcaactgagg
    23761 tgtcagcgca tttccaaata ctgtttcggc ttctccgcct gcataaatat ctgcatgatc
    23821 aaaaaaatta attccacact ccagtgctcc ttcagtcaga cttcttaccg ctttttcatc
    23881 agataaacct gtaattctca tgcatccaat tccaattctt gatacattgt ctattttgtc
    23941 actaatctga aacattttca ttttgtatcc tcctgtatta tacttaattt atgtatttct
    24001 ctttagttaa cgtgtttctt ttattctttt gtccagtttt ttaagtgcaa aaacatatat
    24061 tttcactgca ttcttcagat tttcaaacaa ttccgcttca tccgcacaat gacagtttcc
    24121 atgtcctttt ggaagtccga gcctgtctag atttcgctcc tgtccagggc caaatgccac
    24181 tgcattggga attttcctcg cataagttcc tcctcccata acaaatggtc tgccttcaag
    24241 acctgtaacc tccctccatg cttccatcag agtctgtatg aaaggctgtt ccggattcat
    24301 ataatatggt ctgctgtctt caataccaat gatgcgaatt cctgatttag cagcttctgt
    24361 ttgcagcttc ggaagaaaat cttctgtttt tttagtaact ggataacgga tgtcaatcac
    24421 tattctcaaa tgtccttcgt gcagaaatgc ctgacctata ttgcatgtca gtctaccaga
    24481 acattcatca gaacaacaaa tttctgtttt ttccccataa ccgccttctg aaagtctctc
    24541 cacaaattct aatgctcttt ttgtctgttc aggaaaattt tgcattttca actttccaca
    24601 aagtatacct attgcatttt gagttccatc cggaaaagct gcatgtccac tgattcccac
    24661 tgctgtttct tcgctctttt gtcctatttt gttctccgca accgcatgag caaaagacgg
    24721 cacgctgtta ggcgcagtcc ctccgtcaaa ttccagaatc ccctctactg cactaacagt
    24781 ttccatcaac acaatacaat gtcctttttc tccgcaacat acgggaaatc cacaatcagc
    24841 aacaaaagaa tattccggtg cttttttgta tttcagataa tattctacat ctgtcatgcc
    24901 gctttcttcc tgacatccaa gaatctgcct tactttaata ttattcagaa tttctttttc
    24961 cctacaatat ttcattgcat ataaaacagc aactgcggga cctttattat cctgtactcc
    25021 acgcccaatt aaatagccat ccttttctgt acacgtatag ggcggatata tccatccttt
    25081 tccttccgga actacgtcca gatgattcca tattccaatc tcaacattcc ctttgcctgt
    25141 agcaatagtc agacagtgac cgtctatatc ttctgtctcc atctgttctc tcaatccaaa
    25201 tgctcgcatc tgttccagtg cttccctgca tttttttcca tatggtgccc ccggaattgc
    25261 ttcctgctga tcagcaatac tcgggattct gatcaatgct gcaatatctt ctcgcatctg
    25321 atcttcctgt ctggagatcc attgttct
//
