LOCUS       c00008_gnlPro..        12698 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FENMDNED_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 09:32:23
            Original ID  :: gnl|Prokka|FENMDNED_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12698
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12698
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[227:2698]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      228..2698
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..12698
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12698
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             3..104
                     /locus_tag="ctg8_1"
                     /transl_table=11
                     /translation="KSQSTREIIYTNFLTVSKDHQVTPLMKKIIDAI"
     CDS             228..1022
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_2"
                     /sec_met_domain="Amidinotransf (E-value: 8.8e-72, bitscore:
                     233.4, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLHRPGKELENLAPDILHRMLIDDIPYLKIAQEEHDAFAHVLRQQ
                     GIKVLYLEDLLAESLTDEKVRRAFLDQLLDESSIKKQDPLHQLLLNYLQELPTKEMVKT
                     VIAGIRKSAIHNSTPSLADLAEDPDYPFYLDPMPNVYFTRDQQAAIGSGMTINRMTFRA
                     RRRESLFMETILKNHPDFKNATIPVWRDRYHHGRLEGGDELVLNNHVLAVGISQRTSAT
                     AITDLAHNLFGHSSYDTILAIKIPHNHAMMHLDTVFTMINYD"
     CDS             1128..1406
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_3"
                     /sec_met_domain="Amidinotransf (E-value: 4e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VQVLKENLHLSELDLIPTGGGDPIAAPREQWNDGSNTLAIAPGEV
                     VTYDRNYVSNDLLRKHGIIVHEIRSSELSRGRGGPRCMSCPLIREDL"
     CDS             1417..2064
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_4"
                     /sec_met_domain="OTCace (E-value: 4.8e-10, bitscore: 31.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 7.3e-48, bitscore:
                     153.8, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSFLDCKDYTPAEISYLIDFALHLKELKKEHIPHE
                     YLKGKNIALLFEKASTMTRSAFVVACNDLGAHPEYLGASEIHLGKKESVKDTAKVLGSM
                     YDGIEYRGFAQEDVEELAKYSGVPVWNGLTDKWHPTQMLADFMTMKEKFGHLKGLTLAY
                     VGDGRDNVADSLLVCGSMLGVNVHIVTPKPLFTHPDVQKLLKILPKIQVQKI"
     CDS             2093..2698
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_5"
                     /sec_met_domain="OTCace (E-value: 7.9e-18, bitscore: 56.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="AA_kinase (E-value: 3.7e-21, bitscore:
                     67.2, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGTPDDQLIFMHCLPAFHDRTTQVGEEIYEKYGLNEMEVTDEVF
                     NSKYAWQFTEAENRLHSIKAVMAATLGNLFIPIACGGGGIPVIVKDGHLRGVAGVIDKD
                     FSAAKMAEDINADELVILTTVDHAFLNYGKENQQAIGKIKVEQLKQYLAEGYFAAGSMK
                     PKIEAAIEFVEKTGNLAIITSLSNANKLADGVGTIVYN"
     CDS             2712..3248
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDIKMNI
                     PGPIKNNRYLTKMFMFGINELENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKR
                     STIDFEDQTSLGRLFDADVLVKNKQAAISRRDLGRQPRKCFLCDRPAKECARSRRHSVE
                     QMQAFISQLYQEYVA"
     CDS             3364..4530
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_10"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_7"
                     /sec_met_domain="Acetyltransf_10 (E-value: 9.3e-08,
                     bitscore: 23.5, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLKKNKNNLKQITALIQYAFLKNNDLTKDENFMSRYDHSTGYGY
                     FDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASYPEYRGQGHISQLMKEILHELHRQD
                     IPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIVRGKWDNLAVQNG
                     VIQLYERQLHTNDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERPMSYLIYRIRDNT
                     FLADEMYAITPQGLLSMFGFMGSHAGSVKQFKMSVPEKSLRAELFPEQNELQVDLRPYM
                     MSRIIDFEKVLACMRPMQEGDFNLEVNSDEQCPWNIGVWQLSNHGRKVAVERKEDALVD
                     FSGSITAWTQVLLGRLTMNAAVKLGLITDYRIQKLDFVKGDVSFYDYF"
     CDS             4546..4707
                     /locus_tag="ctg8_8"
                     /transl_table=11
                     /translation="MSKEKKLNLIKLFGIVVSGLNLIFFALMALNKHEDTKDKRRVAEE
                     GHAPLDEK"
     CDS             4697..5314
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_9"
                     /sec_met_domain="LysR_substrate (E-value: 1.5e-13,
                     bitscore: 42.0, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNKMTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLATSHD
                     GAFAKLNEDEADIAINDLRDENLNFDETELTQAGVMAILPKGMYPNGIQMIEKDELNDM
                     TCFIVAKPEEEVSELHLFKDLYQIGSQFIASNSVEEAVLLVASGSGYFILNENTARLIN
                     TADLQPLFLLDHGQLIKQKIMAFYKSNSALSSEFIKLLQQEY"
     CDS             5413..5952
                     /locus_tag="ctg8_10"
                     /transl_table=11
                     /translation="MLKRTLLPLTSMVLVLGLTGLASQVETVDASTYGNGVQVTIPKKM
                     QGTWYSYDRNAHNGTKITFTEHTVNGKPIFTQEASTISDYFNGRIANQKNFDKVTQNWM
                     SGKTTKMKNDTFYEIDPWITFENWSLYRVVPQTINGKKHNVLVYSSRYDGGNYFRSKKL
                     AKKMKDYKFKKVNYTL"
     CDS             6048..6710
                     /locus_tag="ctg8_11"
                     /transl_table=11
                     /translation="MKLKQTPILRLYKLETNKEDHAKFVKAGQHNMLTSQENEPGTLFM
                     QTSHNEETTNFVVECYQDEASYDTHANSKQFKDFTDVSKDILTSRVKVELFPEFISTKA
                     EKLAVTGSNDYVIYLTEIGVSLGKGDEFAHAVMKEMKTAVEEEKDILAMIAGTVADQPN
                     EWLAIEVYRNNEAYKQHLETKNFKEYLNNTKYCVESKSLRKLQPDVIVDQGAIFYQP"
     CDS             7281..8318
                     /locus_tag="ctg8_12"
                     /transl_table=11
                     /translation="MPGIVEQTLLEQQNIDLNEMVTMNQMIDQLLPNASKELQQKLKIK
                     IYNFVRTRKQPSITVRRRKYFKPAVAKLIIGNVQDYADAIERRAKEAPAKEDATDKKPA
                     SKSKRVRTITKRKILAKVIKNDKIDKSIQKKLEDKIASIVKTNFIKPVNKRGSFSVEDG
                     EKVIAELSPFYQNIKIDQKYRKNAEKAAENKETETKEKPEQHSKDQNESREGQSKDFER
                     KNNQKNSNNRNNNQTQNQRKRQNKHPFEIRRENNNRSRNNQSNRRYNNRNNYDSRNNYE
                     FDEASGLRERYNTVIRNYNQLEQRYNALQDKYNQALDDKARLIEEMGKKNEDLRRVLID
                     VLRKM"
     CDS             8492..10090
                     /locus_tag="ctg8_13"
                     /transl_table=11
                     /translation="MSLKELFKSNVFRACIIILLYVLYALFGSFSEYLFKYALNSITAG
                     NFNTYVYWQIMQFVLALFTSLLLPITTVVFTRQTQNYLHKIRQEIMHHYYDEKSDEKVS
                     SMQNRLTANLKILSDDYATPWITILSGILEIVIAIVLLASMNWILILVTAILAVITLFA
                     PKIMEKKTSAATDKVNKKNEKLLNTIAHWLGGLQELRRYSAYSRLVKQIHRSSSDYVDA
                     SKGSAKLRSVSYLINAFSNSIAQIGMSFIAGIMFLLNMISFGDFAVASGFAFTIFSAIW
                     NITQSLTQVKSTKALREQITDLRKQVPDENKDKVSAYGLKVSGLSVKYDQGETIFYPDF
                     TIKKGQKVLLTGDSGTGKSTLFNVLLGKLKPESGTVTYLDENETIIPEGKARIGNMPQN
                     PVVFPATIKENITMFNENLQDKLQDVVQAVQLQSDLAKMPDGVNTTIDLKSENLSGGQR
                     QKVVLARTEIHEQSFVLMDEVTSAIDQKATEKIIDELLKTDQTILMIAHNFTPELKAKF
                     DQEIKLKSKKGDKVR"
     CDS             10087..11670
                     /locus_tag="ctg8_14"
                     /transl_table=11
                     /translation="MNLKAFIKTNPVRFWLTAIGWIIIPALSITNTYVVQEETNILLSR
                     NWTKFILINVLAFLIMLVDYGVSALVDYQQQAQVQDLNDQVRDKIVKRYYYDGRKHTVA
                     QMQNRLTNDLQMLNNNYFINVFLLIYGVSTIVFVLIYLILLSWQLLLAICLMVAISLLL
                     PKLTEKPLQKATELISDSNQKYLDTLNDWLSGLDQLQQFLAGAKLFSVIEKTSKKLEDA
                     NVKQTAYIKLLNAVNGIVSAAFGLALFVLAGWLVKNHQIPIGALLVVGNFRYYLNGGID
                     TLTNGLGAMKGSKKLLAEVDKSASDIPMQAEKDVVMPNVIKTKDLVLKFPNGEKLTYPD
                     LEIKQGEKILLTGDSGAGKSTLFKLILGELKPSAGKVVYEDKAGKKINPDLSKIGYLPQ
                     DPVVFPASIEENITMFNEKLNGKVKQVINEVNFADDIAKFTEGLDEKINLDKLNISGGQ
                     RQKIVLARAKVHNSDIILIDEGTSAIDQKATMLILKNLLKSKTTIVFIAHNFNEGMHQL
                     FDREIHLVKE"
     CDS             complement(11714..12433)
                     /locus_tag="ctg8_15"
                     /transl_table=11
                     /translation="MTTKIEKISPKIYKVTDNDKHLGTISTYHNLFHNKYIYLKFNLSD
                     YSVNIPFSKIVQAEHQALQVMIDSNENPIVDFLLRNGFICKRHCYTLTVNKKDLKIEIN
                     NKLSLHFFNTESPDYRTCCQLLYKYYKQVHQSVSPLTANIDTFIQEVPTKTGYYSTNEL
                     GEIDNLVFTENNEIAYICSWDRFSSNNFIETILVKMFQNYPSIFFEADDTDWMAYQLLS
                     YFKINKNNSFNTYIFPN"
     CDS             complement(12417..12563)
                     /locus_tag="ctg8_16"
                     /transl_table=11
                     /translation="MIDIIPKIDPDLIFPVLNYEPIYNFIIKNGTDQKLISIIKRIKND
                     YKN"
ORIGIN
        1 aaaaaagtca atcaacgaga gagattattt acacaaactt cttgacagtc tctaaagatc
       61 atcaagttac acctttaatg aaaaaaatca ttgatgcaat atgataatac tgtaactttt
      121 gcctaattga tccataataa atgtaaacgg atacaataat taatagaagg tggttgaatg
      181 tcgagtccga ttcatgttta ttcagaaatt ggtaagttaa aacggtgatg ttacatcgac
      241 cgggaaaaga actagaaaat ctagccccag atattttgca tcgaatgtta attgacgata
      301 ttccttatct gaagattgcc caagaagaac atgatgcttt tgcgcatgta ttgaggcagc
      361 aggggatcaa agtattatat cttgaggatt tattagcaga atctttaaca gatgagaaag
      421 ttcgtcgggc attcttagat cagttactgg atgaatcaag tattaaaaaa caggatcctt
      481 tgcatcaatt attgctgaac tatctccaag aattgccaac taaggaaatg gtaaaaacgg
      541 tgattgctgg aattagaaaa agtgcgattc ataattctac cccatcttta gcagatttgg
      601 ctgaggaccc agattaccct ttttatcttg atccaatgcc aaatgtatat tttactcgag
      661 atcaacaggc tgcaattggt tcagggatga ccattaaccg gatgactttc agagctagac
      721 gacgtgaatc attatttatg gaaacaattt tgaaaaatca tcctgatttc aagaacgcaa
      781 ctattccagt ttggcgtgac cgttatcatc atggtcgcct tgagggcggg gatgaactag
      841 ttctaaataa ccatgtgtta gctgtaggta tttcacaacg cacttctgca actgcaatta
      901 ctgacttagc tcataattta tttggtcatt caagttatga tacgatttta gcgattaaga
      961 ttccgcacaa tcatgctatg atgcaccttg atacagtttt tacaatgatt aattatgatt
     1021 aatttacggt tcatcccttt attttagata aagccggcaa aattgatatt tatgttctac
     1081 agcccgatga tcacaacggt gtaaaaatca cagaaaagaa tgatttggtg caggttttga
     1141 aagaaaactt gcatttaagc gaattggatt taattccaac tggcggtggt gatccaattg
     1201 ccgcaccacg tgagcaatgg aatgacggct caaatacctt ggcaattgca ccaggtgaag
     1261 tcgttactta tgatcgtaat tatgtatcca atgatttgct aagaaaacat ggcatcatcg
     1321 ttcatgagat tcggtctagt gaactctcac gtggtcgtgg cggtcctaga tgtatgtcgt
     1381 gtccgttgat tcgtgaagat ttataagagg caaaaaatga aatatttaca aaatgttttt
     1441 caaggtagaa gttttctcga ttgtaaagac tatactccag ctgaaatttc atatttaatt
     1501 gattttgcat tacatttaaa agaacttaaa aaagagcata tcccacatga atatctgaaa
     1561 ggtaaaaata ttgcactact ttttgaaaaa gcctcaacta tgacgcgatc tgcttttgta
     1621 gtagcttgta atgatttagg cgctcatcca gaatatctag gcgcaagcga gatccactta
     1681 ggtaaaaaag aaagcgttaa ggatacggct aaagtcctag gctcaatgta tgatggaatt
     1741 gaatatcgcg gttttgctca agaagatgta gaagagctgg ctaaatattc tggtgttcct
     1801 gtttggaatg ggttaactga taaatggcat cctactcaga tgttggcaga ttttatgacc
     1861 atgaaagaaa agtttggtca tttgaagggc ttaactttag cttatgtggg tgatggccgc
     1921 gataatgttg ccgacagtct tttagtttgt ggctcaatgt taggtgttaa tgtacatatt
     1981 gttacaccca agcctttgtt tacacatcct gatgtacaaa aattgctcaa aattttgccc
     2041 aagattcagg ttcaaaaaat ttgatcacag atgatattgc ttagggcgtt aaatgactgg
     2101 tacaccagat gaccaattga tctttatgca ttgtttgcca gcttttcatg atcgaacaac
     2161 tcaggtggga gaagaaatct atgaaaaata tggcttaaat gagatggaag taactgatga
     2221 ggtctttaat tcaaagtatg cttggcaatt tacagaagct gaaaatcgat tgcattcaat
     2281 taaagcagtg atggcggcta ctttaggaaa tttatttatt ccgattgcct gtggcggtgg
     2341 tggcatccct gttattgtga aagatgggca tctcagaggt gttgccggcg taattgataa
     2401 agatttttcc gctgctaaaa tggcagaaga tatcaacgct gatgaattag taattctaac
     2461 aacggtggat catgcatttt tgaattatgg caaagaaaat caacaagcaa ttggtaaaat
     2521 aaaagttgaa cagctcaaac aatacctagc agaaggttat ttcgcagctg ggagtatgaa
     2581 gcctaagata gaagctgcaa ttgaatttgt agaaaaaaca ggtaatttag caattatcac
     2641 ctctttgagc aatgccaaca aactagcaga cggagtcggc acaatcgttt ataattaact
     2701 gggtgataaa aatgaatatt tttaatgaag gaaaaaagca ggatattgcc caagttttag
     2761 cagctaaaga taggcgagta gctgtacaac ataagatttt taataagtat cctaatcaaa
     2821 ctctagtcga cattaagatg aatatcccag gaccaatcaa gaataatcgc tatttaacta
     2881 aaatgtttat gtttggtatc aatgagctgg aaaatgcttg gactaaccta ggttatcatt
     2941 ttaaattggt gacacagctt aatgatgata gtggctgtga aaacttctat gtattatctt
     3001 tgtcaattga aaaagtaaag cgctcaacaa ttgattttga agatcagaca tcattgggac
     3061 gtctctttga tgcagacgtg ttggtaaaaa ataaacaagc tgcaatttca cgcagagatt
     3121 tgggcaggca gccacgtaag tgctttttat gtgatcgccc tgctaaagaa tgtgctcgca
     3181 gccggagaca ttcagtggaa cagatgcagg catttatctc tcagctttat caagaatacg
     3241 ttgcgtaaaa taaaccggga ttttatgatt ccggtttatt tttatgaaaa atctagttaa
     3301 aaattaaaaa aatgaactaa aatagtaatg aataaattta tagatgtacg tataggaata
     3361 agcatgaaat taaagaaaaa taagaataat ttaaagcaaa ttacggcatt aattcaatat
     3421 gcatttttga aaaataatga tttgactaaa gatgaaaatt ttatgagtcg ttatgatcat
     3481 agtacaggtt atggctattt tgataaggaa aaattagcta gctatattat ggttaatcga
     3541 tttaaaagtg atgtttttgg gcatcattta ccgatggctg gaataggtta tgtagcttca
     3601 tatcctgagt atcgtggcca aggtcatatt tcccaattaa tgaaagaaat tttgcatgaa
     3661 ttacataggc aagatattcc gtttgctaac ctggcaccat tttcggagag cttttatcgc
     3721 cagtacgggt ttagcaatag tatttatcaa aaagaatatc gctttgatgg aagcgcattg
     3781 cgtagtttta aattaccacg ttctggtcat atagtgcgtg gcaagtggga caatttagct
     3841 gttcaaaatg gtgtgattca actttatgaa cgtcaactgc atactaatga tgaacgtaac
     3901 acggttgtac gtgaggcatg gtggtggaat agacttgatt cttattatca tcaccgcaat
     3961 gtagccgttt attttgacgc agatgagcgg ccaatgagtt acttgattta tcgcattaga
     4021 gacaatactt ttttagctga tgaaatgtac gcaattacgc cgcagggatt actgagtatg
     4081 tttggtttta tgggttcgca cgcgggcagt gttaagcaat ttaaaatgag cgtaccagag
     4141 aaatcgttac gagctgaact ttttcctgaa caaaacgaac tccaagttga tttgcgtcct
     4201 tatatgatga gtcgaattat tgattttgaa aaagttttgg cttgtatgcg gccaatgcaa
     4261 gaaggtgatt ttaatctgga agtcaatagc gatgaacagt gtccttggaa tattggagtt
     4321 tggcaattaa gtaatcatgg acgtaaggta gcggtagaac gtaaggaaga tgcattggtt
     4381 gatttttcgg gatcaattac cgcgtggacc caggtactat taggtagact aaccatgaat
     4441 gctgctgtta aactaggatt aattacagat taccgcatcc aaaaattaga tttcgttaaa
     4501 ggcgatgtat cattttatga ttatttttag ttgtgaggtt aaaaaatgag caaagaaaag
     4561 aaactcaatt taataaaatt atttggcatt gtagttagtg gtttgaattt gatctttttt
     4621 gccttgatgg cacttaataa gcatgaagat actaaggata aaagaagagt agcagaagaa
     4681 ggacacgcac cgctggatga aaaataaaat gacggaatta aagattgcat attttgacca
     4741 attaggtcgt aaggaattag atcaggcagt gcagcatttt gtgttaaaac atcctaatgt
     4801 agatgtaaaa ctacttgcga ctagtcatga tggtgctttt gcaaaattga atgaagatga
     4861 agcagacata gcaatcaatg atttgcgtga cgagaatctt aactttgatg aaacagaatt
     4921 gactcaagct ggtgtaatgg caattttgcc caagggaatg tatcctaatg gcattcaaat
     4981 gattgaaaaa gacgagctca atgatatgac ttgttttatt gtggctaaac ctgaagaaga
     5041 ggttagtgag ctacatttat ttaaagattt gtatcaaatt ggcagtcaat tcatcgcttc
     5101 taactcggtt gaagaagcag tactgttggt cgcctctggg tctggctatt ttattttaaa
     5161 tgagaatacg gctaggttaa ttaatactgc agatttgcag ccacttttct tgcttgatca
     5221 tggtcagtta ataaagcaaa agataatggc tttttataag tcaaattcag cgttaagtag
     5281 tgagtttata aagctattgc agcaagaata ttaatctgta aagttaaaaa tatcttgtct
     5341 aagtactata agatactgta aaatatatta tgaaagcgga ttcatatatt ttacattctg
     5401 gagatgattt ttatgctaaa aagaactttg ttacctttaa catcaatggt acttgtttta
     5461 ggattaactg gtttggctag tcaagttgag actgttgatg cttcaactta tggtaatggt
     5521 gtacaggtta ctattccaaa aaagatgcag ggtacttggt actcttatga tcgtaatgca
     5581 cataatggca caaagatcac ctttactgaa catactgtta atggcaaacc aatatttacc
     5641 caggaggctt cgacaattag tgattacttc aatggtagaa ttgctaacca gaagaacttt
     5701 gataaggtaa cgcaaaactg gatgtctggt aaaactacca aaatgaagaa tgatacattc
     5761 tatgagattg atccgtggat tacttttgaa aattggagtc tttatcgagt ggtaccacaa
     5821 accattaatg gtaaaaagca taacgtgctg gtttattcta gtagatatga tggtggtaac
     5881 tacttcagaa gcaagaaatt agctaaaaaa atgaaggact acaagtttaa gaaagttaat
     5941 tacacgttat agttttgtga catcccttaa ctaagggatg ttttttacta atagacgcgg
     6001 taaaatttag tataatagtg acaaaattaa ttcttggagg agaagttatg aaattaaaac
     6061 aaacaccaat tttgcgttta tataaactag aaactaataa agaggatcat gcaaagttcg
     6121 ttaaggcagg gcaacataat atgcttactt ctcaagaaaa cgaaccaggc acattgttta
     6181 tgcagacaag tcataacgaa gaaactacta attttgtagt agaatgctat caagacgaag
     6241 caagttatga tactcatgct aattcaaagc aatttaagga ttttactgac gtttctaaag
     6301 atattttaac tagtcgagta aaggtagaat tgtttccgga atttatttct acaaaggcag
     6361 aaaaactagc agttaccgga tcaaatgatt atgttattta tctaactgaa attggtgttt
     6421 ctttaggtaa gggcgatgag tttgctcatg ctgtaatgaa agaaatgaaa acggcagtcg
     6481 aagaagaaaa agatattttg gcaatgattg caggaactgt tgccgatcaa ccaaatgaat
     6541 ggttagctat tgaagtttat cgtaataatg aagcttacaa gcagcacttg gaaactaaga
     6601 acttcaaaga gtatttgaat aatacaaaat attgtgttga aagtaagagt ttacgtaagt
     6661 tgcaaccaga tgtaattgtt gaccaaggtg caattttcta ccaaccataa agaataagac
     6721 gaaaagaaga ccaggctatg tggagtacat aacctggtct ttctagttag aggggaaaaa
     6781 gatttattaa catatattat tctggttttt agtggcgatg ttttaccttt gctactgctg
     6841 gtttattaat taatactgag ctgatggcca ttaaaccaag cgttaaaaat gatccaccaa
     6901 ttaagagtag tttaatcaag gttctcattc ctttcatctt aattgatctt ataatagcga
     6961 aataatatta agaatttata tgtaaaacct aatggattag ttaagaaaat aaaactagaa
     7021 aaaaggctgg ttagcacgta aaatagaaat agagtcaaag tctagtgcaa ctgcgcataa
     7081 aataaagcag tatcgatggg atgctgcttg ttttggttaa aaaatagaga atatgcttgt
     7141 agcccttttc gtaaatagcg ttaatgttgt aaaatggaaa gtgcattaag tttattaatg
     7201 agaaaattga tgtattattg caaaaaaggc cgtaatggcc ctttttgttg tgaaaaaact
     7261 aaaagaatat aggattggaa atgccaggaa tagtagagca aacattatta gaacaacaaa
     7321 atattgattt aaatgaaatg gtaacaatga atcaaatgat tgatcaattg ttgcctaatg
     7381 caagtaaaga attacaacaa aaactaaaga ttaaaattta taactttgtg cgtacacgta
     7441 aacaaccaag tattactgtg cgaagaagaa aatattttaa gccggctgtt gctaaattaa
     7501 ttattggtaa tgtacaagat tacgcagatg caattgaacg tcgtgctaag gaagccccag
     7561 ctaaagagga tgctactgat aagaagccag cttctaaatc taagcgggtt aggacaatta
     7621 ctaagcgtaa gattttagct aaagttataa agaatgataa gattgataaa tctattcaaa
     7681 agaaattaga agataagatt gcttcaattg tgaagaccaa ctttattaag ccagttaaca
     7741 agcggggaag tttttcggtt gaagatggtg aaaaagttat agctgaactt agtccttttt
     7801 atcaaaatat caagattgat caaaagtatc gcaagaatgc tgaaaaagcg gctgaaaata
     7861 aggaaacaga aactaaagaa aagcctgagc aacattctaa ggatcagaat gaaagtcgtg
     7921 aaggtcaatc taaggacttt gagcgtaaga ataatcagaa gaatagcaat aatcgaaata
     7981 ataatcaaac gcaaaatcaa cgtaagcgac aaaataagca tccttttgag atcagaagag
     8041 aaaataataa ccgctcacgt aataatcagt ctaaccgccg ctataataat cgaaataatt
     8101 atgatagtcg gaataattat gaatttgatg aagctagcgg tttgcgtgaa cgctacaata
     8161 cagtaatcag aaattacaat caactggagc aaagatataa tgctttgcaa gataaatata
     8221 atcaggcttt agatgataaa gctagattga tcgaagaaat gggcaagaag aacgaagact
     8281 tacgtcgtgt attgatcgac gttttgcgaa aaatgtagtt tttggtaaag aaagagacta
     8341 gtagtcaatt tgaattgatt actagtctta ttttatgttt atgaaatatg atttagctta
     8401 aaaattaaaa aaatatgtgt aaaaaattat ttttgtgtag taatattaaa ggatgataaa
     8461 tatttttatt aatgattaat ggaggagaag tatgagttta aaagagctat ttaaaagcaa
     8521 tgtgtttcga gcctgcatta ttatcttatt gtatgtttta tacgcattat ttgggagttt
     8581 tagtgaatat ttatttaaat atgctctgaa ttcaattact gctggtaatt ttaatacata
     8641 tgtttattgg caaataatgc agtttgtttt agcattattc acttcgttgc ttttaccaat
     8701 tactaccgtt gttttcacta ggcagacgca aaactatctg cataaaattc ggcaagaaat
     8761 catgcatcat tactatgatg aaaaaagtga tgaaaaagtc tctagtatgc agaaccgatt
     8821 aacagccaat ttaaaaatct tatcagatga ttatgctaca ccttggatta ctattttaag
     8881 tgggatttta gagattgtga ttgctattgt tttactagca agcatgaact ggattctaat
     8941 tttggttact gccattttag ctgtgattac actttttgct cctaaaatta tggagaagaa
     9001 aacatcagct gccacagata aagtaaataa aaagaatgaa aagctgttaa atacaattgc
     9061 tcattggctt ggtggattgc aggaactacg tcgttatagt gcatacagtc gtttggttaa
     9121 gcaaattcat cgatcaagta gtgattatgt ggacgcaagt aagggtagtg caaaattaag
     9181 aagtgtaagt tatttgatta atgcttttag caattcaatt gcacaaattg gtatgagctt
     9241 tattgctgga atcatgtttt tgcttaatat gatttcattc ggtgattttg cagttgctag
     9301 tggttttgca tttacgattt tttcagcaat ttggaatatt actcagtcgt taacgcaagt
     9361 taagtcaact aaggctttac gcgaacagat taccgattta agaaagcaag ttcctgatga
     9421 aaataaagat aaagtatcag cctacggtct taaagtttca ggcttgtctg taaaatacga
     9481 tcagggggaa acaatttttt atcctgattt tacaataaaa aaagggcaga aagttttgct
     9541 tactggcgat tcaggaacag gaaaatcaac cttgtttaat gttttgttag gtaagctaaa
     9601 acctgaatct ggtacggtga cctatctaga tgaaaatgaa actatcattc ctgaaggaaa
     9661 agctagaatt ggcaatatgc cgcaaaatcc agtagttttt cccgcaacga tcaaagagaa
     9721 cattacaatg tttaacgaaa atttgcagga taagcttcaa gatgttgttc aagcagttca
     9781 actccaatcc gacttagcca aaatgccaga tggtgttaat acaacaattg atctaaaaag
     9841 tgaaaatttg tctggtggac aacggcaaaa agttgtttta gcgcgaacgg aaatacacga
     9901 gcaatcgttt gttttaatgg atgaagtaac tagtgcgatc gatcaaaaag ctaccgaaaa
     9961 aatcattgat gaattgctca aaacagatca aactattttg atgattgctc acaactttac
    10021 gccagaatta aaagcaaaat ttgatcaaga aattaaatta aaaagtaaga aaggggataa
    10081 agtaagatga atttaaaagc ttttattaaa accaatccag ttcgtttctg gttaactgca
    10141 attggttgga ttattattcc tgctttatca attaccaata cttacgttgt acaagaagag
    10201 acgaatatcc ttttaagtcg taattggact aagtttattt taatcaatgt tcttgctttt
    10261 ctgattatgt tagttgacta tggtgtgagt gctttagttg attatcagca gcaggctcag
    10321 gtacaagact taaatgatca agttagagat aaaattgtta agcgatatta ttatgatggg
    10381 agaaagcata ctgttgcaca gatgcaaaat cgtttgacta atgatttaca aatgcttaac
    10441 aataactact ttattaatgt cttcttattg atttatggtg tgtcaacgat cgtttttgtt
    10501 ttaatttatc ttattttatt gagttggcaa ttattgctgg ctatttgttt gatggtagct
    10561 atttctcttt tgctgccaaa gttaacagaa aagccgttac aaaaagcaac agaattaatt
    10621 tctgacagca atcaaaaata tttagataca ttaaatgatt ggttatctgg tctggatcaa
    10681 cttcaacaat ttttagctgg agctaaacta ttttccgtaa tagaaaaaac atcaaaaaaa
    10741 ttagaagatg ctaatgttaa gcaaacggct tatattaaac tgcttaatgc tgtaaatgga
    10801 attgtttccg cggcttttgg tttagcattg tttgtgcttg ctggttggtt ggttaaaaat
    10861 catcaaattc caattggtgc cttattggta gtcggtaatt ttcggtatta cttaaatgga
    10921 ggaattgata cacttactaa cgggttagga gcaatgaaag gtagtaaaaa attacttgcc
    10981 gaagttgata aatctgctag tgatattccg atgcaagctg aaaaagatgt agttatgcct
    11041 aatgtaatta aaacaaaaga tctagtttta aagttcccta atggagaaaa attgacttat
    11101 cctgatctgg agattaagca aggcgaaaag attttattaa ctggcgattc tggtgcaggt
    11161 aagtctactt tgtttaaact aattttaggt gaacttaagc ctagtgcagg taaagttgtt
    11221 tatgaggata aggctggtaa gaaaattaat cctgatttga gtaagatagg ttatttaccg
    11281 caagatccag tagtttttcc agcatcgatt gaagaaaata ttacgatgtt taatgaaaaa
    11341 ctgaatggaa aagttaaaca agtaataaat gaagtgaact ttgctgatga tatcgctaag
    11401 tttactgaag gactagatga aaagattaat cttgataagc tgaatatttc cggaggtcaa
    11461 agacaaaaaa ttgtattggc tagagcaaaa gttcacaata gtgatattat cttgattgat
    11521 gagggaacta gtgcaattga tcagaaagct acaatgttga ttttgaagaa tttattgaaa
    11581 agcaaaacga cgattgtttt tattgcccat aactttaatg aaggaatgca tcagttgttt
    11641 gatcgagaga ttcatttagt aaaagaatag ttgaagaaag acactgcatt tttagggatg
    11701 cagtgtcttt actttagttt ggaaagatat aggtattgaa actgttattc ttatttattt
    11761 taaaatagct tagtaattga taagccatcc agtcagtatc atctgcttca aaaaatattg
    11821 aaggataatt ttgaaacatt ttaactagaa tagtttcaat aaaattatta gaactaaacc
    11881 tatcccaaga acagatgtat gcaatctcgt tgttttcagt gaatacaaga ttatctattt
    11941 ctccgagttc attagtacta taatatccag tttttgttgg aacttcttgg ataaacgtgt
    12001 caatattagc agttaatggt gacacagatt gatgaacttg tttgtaatat ttataaagta
    12061 attggcaaca tgttctgtaa tcgggacttt ctgtattgaa aaaatgaaga gataatttgt
    12121 tattgatctc aatttttaaa tcttttttgt taacggtaag cgtataacag tgtcgtttgc
    12181 agataaaacc atttcttaat aaaaaatcta cgattggatt ttcatttgaa tcaatcatga
    12241 cttgcaatgc ttggtgctct gcttgaacta tttttgaaaa tggaatattt acagagtaat
    12301 cacttagatt gaattttaga taaatatatt tgttatgaaa aagattgtga taagtagaaa
    12361 tagtgcctag atgcttatcg ttatcagtta ctttgtagat tttaggagat attttttcaa
    12421 tttttgtagt cattttttat ccttttgata attgaaatta atttttgatc ggttccgttt
    12481 ttaattatga agttataaat cggttcataa ttgagcacag ggaaaataag atcaggatca
    12541 attttaggta taatgtcaat cattgatttc ttactaatta cgttgagatt tttagcttct
    12601 tgagcatttc ttatctttct ttttgcttgt gaaggaggat aaccttgtcc ccaaggctgt
    12661 tcaaaaagat tttttatagt ctactcaaaa ttgatttc
//
