LOCUS       c00108_gnlPro..        17275 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CPPDHDIG_108.
ACCESSION   c00108_gnlPro..
VERSION     c00108_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:48:57
            Original ID  :: gnl|Prokka|CPPDHDIG_108
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17275
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17275
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3804:7275]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3805..7275
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..17275
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17275
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             2..88
                     /locus_tag="ctg108_1"
                     /transl_table=11
                     /translation="ITTHCFKLFLYKSVAEIRYMSFGYSFFV"
     CDS             85..660
                     /locus_tag="ctg108_2"
                     /transl_table=11
                     /translation="MMSGQVIGQNKSAESHSHTCKTVLALKNNLLYDLALAPNIEVELP
                     LGKRWSLNVEYKCPWWSDSGCNFCYQLLSGGTEARYWLGNRHTRGRLSGHFLGAYAEGG
                     TYDFQLKKEKGYRGKYYAAAGITYGYVRPLARHLAIEFSVGIGYLDTEYRKYTSYGNDL
                     VWVSSGKYHFIGPTKAKISLVWLLTSGR"
     CDS             636..1640
                     /locus_tag="ctg108_3"
                     /transl_table=11
                     /translation="MASNVGEMSGMKDARHMILWLFFGLLPMLGSCDFRDMLDDYPVSG
                     VQIKLDWKGVTDKLPQTMRIIFYPKDTQGRKVESYLPAGGGEVKVPPGKYAVVAYNFNT
                     ESIQIRGDESYETIEAFTGHCTGLDVHENMVWSPDPLYVVALDEVEIGQSDVALPLDWK
                     PEAVVDHYSFDIKVEGWDRISSIICHVDGLNGSYFIGNRACHLSEVPICVDTKRENGLL
                     WGYFSSFVLLKDTKTRADSPMLLTLKIVKRDKTVQEVKVDITEVIETAPPSGGGEEEPD
                     VGVPGSEIHIEVPVPEDKVVVDDLEPGTDEGDGGIGGDVDDWDDETDVELPVN"
     CDS             1686..2654
                     /locus_tag="ctg108_4"
                     /transl_table=11
                     /translation="MKKVLFLALAAAAVMSCSESEEIENAGQKAEIKLGTVVGNTTRAT
                     VTDLPELQKVGFTVYAYNTGATAMASVATFDAMKEFMTDVKVTYSAPNWSLTGGTYYWP
                     MTDNLQFFAYGNPGTGALTYNQPAAGAIYPSITYTVADVAAQTDLVAAKVTDATKASNA
                     SGVSLKFGHILTQINFTVKAADALTYKLKTLTISGVHNKGTYGFDDSTWKSQEGTATYA
                     HTIAGSALEVNTTGVEMNAAWMLMPQTLDTNAKINVVYDIYEKDVLLDTVTSAIDLNDT
                     QAWGEGKKIRYTLTLANKAAKVTFVPEVGPWSTADDTNVEK"
     CDS             2803..3666
                     /locus_tag="ctg108_5"
                     /transl_table=11
                     /translation="MPNSSACRGKKQCAQCPKAVDNAIIYASHPRGFHLPARKCEENII
                     IFLLKGEVLVNSKEYAGTVLHAGEFILQAIGSKYEILAMTDVECVCYRFSKPEFFCEDR
                     YNHIMKEVTPPLIFYPLTITPELQLFLESSKAYLSEEKICREILCFKRKELAFILGNYY
                     SDYELSMLIHPLAQYTNSFHYFVLQNHAKVKTVEELAQLGGYTVATFRRIFNSVFHQPV
                     YEWMMERRKESVVYELRYTDASISEICYKYGFESLPHFSNFCKKNFGASPRSLRAGNLS
                     EVNGMS"
     CDS             complement(3805..4560)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_6"
                     /sec_met_domain="Fer4_7 (E-value: 4.1e-12, bitscore: 38.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.3e-25, bitscore: 81.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.5e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNVSISNIARLNRDFIIAKLKD"
     CDS             complement(4594..6462)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 199.9; E-value:
                     2.5e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_7"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.9e-61, bitscore:
                     199.9, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.5e-37,
                     bitscore: 118.9, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNPANKRRLDIIVVGTGLAGASAAASLGEMGFRVFNFCIQDSPRR
                     AHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKGGDYRAREANVYRLAEVSNNIIDQCVA
                     QGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQTGQQLLLGAYSALSRQVNVGTVKLYTR
                     YEMEDVVLIDGRARGIIAKNLVTGKLERFAAHAVVIATGGYGNAYFLSTNAMACNCSAA
                     MACYRKGAWFANPAYVQIHPTCIPVHGDKQSKLTLMSESLRNDGRIWVPKKLEDAKKLQ
                     EGTLQGKDIPEEDRDYYLERRYPAFGNLVPRDVASRAAKERCDKGFGVNNTGLAVFLDF
                     SEAINRLGKDVVAQRYGNLFDMYEEITDVSPYENPMMIYPAIHYTMGGIWVDYELMTSI
                     KGLFAIGECNFSDHGANRLGASALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEF
                     AAAEKAVQEKIDWMMNIKGKKSVDSIHKELGHIMWEYVGMGRTAEGLKEGLKKLKEVRK
                     EFEKELFIPGDKEGMNVELDKAIRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEG
                     EAKRDDENYFYVACWEYQGSDEKEPVLLKEPLVYEAIKVQTRNYKS"
     CDS             complement(6577..7275)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_8"
                     /sec_met_domain="SucD_FumR (E-value: 3.2e-129, bitscore:
                     419.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVALVSANGYNMV
                     CEFLGANWYALVATVGLAALFIIHIIYAFWLTMQNRKARGSERYAVTEKPKTVEWASQN
                     MLVLGIIVIVGLGLHLVNFWAKMQLPELMHNMGMHADTLTLAYAANGVYHIQNTFSNPV
                     FVVLYLVWLGALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLCFALVVVV
                     FFAKSLCGAC"
     CDS             complement(7438..8271)
                     /locus_tag="ctg108_9"
                     /transl_table=11
                     /translation="LVYRHYPKGQHFSAEKCTQNCMIFMLKGELLVNSDEYPGTTLQSR
                     QLILQAIGSKVELLALTEVEYIVYWFTELPLICEERYKEILKRSEAPLTYTPLTAISML
                     EGLLKSLACYLNEQPYACSKYIEMKCQELVYILTCYYPLHQISTFFYPISTYTESFQYF
                     VMQNYDKVKNVEEFAHLGGYTTTTFRRLFKNMYGVPVYEWILDKKREGILNDLQYTKQR
                     ISVISARYGFDSLSHFAHFCKDSFGDTPRALRKRSANGEKISIICKEQGKDQEDE"
     CDS             complement(8584..8793)
                     /locus_tag="ctg108_10"
                     /transl_table=11
                     /translation="MAICMHSVGIFIIRTLTVHQIFHSISHNKSPRYTCTYVDRIFQQT
                     LIMFYPSGNRHRHRNTDSNIGLRT"
     CDS             complement(9131..10753)
                     /locus_tag="ctg108_11"
                     /transl_table=11
                     /translation="MEMMKKLFTIIICICAVTAQAQKPNNEALRKLQMAEFAITNLYVD
                     KVDEDKLVEEAIIKMLAQLDPHSTYNNAEEVKKMNEPLQGNFEGIGVQFQMIEDTLLVI
                     QPVSNGPSEKVGILAGDRIVAVNDSAIAGVKMSTEDIMSRLRGPKDSEVKLTIVRRGVD
                     DQLYFTVKRDKIPILSLDASYMIQPKTGYIRINRFGATTAEEFAEALKSLQKKGMKDLI
                     LDLQGNGGGYLNAAIDLANEFLKQKELIVYTEGRAARRSDFFAKGTGNFKNGRLIILVD
                     EYSASASEIVTGAIQDWDRGVVVGRRTFGKGLVQRPIDLPDGSMIRLTIARYYTPSGRC
                     IQKPYDSTANLDSRLTGENSQDKYNQELIDRFNHGEMIHADSIHFADSLKAQTKRMGRT
                     VYGGGGIMPDFFVPIDTTQYTDYHRNLVAKGVVIKATTGYIEKHRKELQNKYKKFEAFN
                     EKFEIDDNFLAEIRTLADKEKIKFDEKQYNQSLPLIKTQLKALIARDLWDMNEYFQVMN
                     STNQSVQQALKVLNEGIYSTIIQ"
     CDS             complement(10797..11255)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg108_12"
                     /sec_met_domain="CTP_transf_like (E-value: 2e-18, bitscore:
                     58.6, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRAIFPGTFDPFTIGHSSVVSRALTFIDEIVIGIGINENKNTYF
                     PLEKREQMIRDYYRNEPRIIVQSYDCLTIDFARQVDASLIIRGIRTVKDFEYEETIADI
                     NRKLTGIETILLFTEPELTCVSSTTVRELLQYGKDISMFIPEGMEIRD"
     CDS             complement(11252..13186)
                     /locus_tag="ctg108_13"
                     /transl_table=11
                     /translation="MEDNNNMTLPLEEADNNITESPVSSVEYTDDNIRHLDDMEHIRVR
                     SGMYIGRLGDGSQNDDGIYVLLKEVMDNSIDEFKMGAGKRIEVTIEDSLRVSVRDYGRG
                     IPQGKLVEAVSKLNTGGKYDSKAFKKSVGLNGVGIKAVNALSSRFEVRSYRDGKVRTAI
                     FEKGTLLSDVTEDSTEESGTYIFFEPDATLFLNYSFQNQFVETLLRNYTYLNTGLTFIY
                     NGQRIVSRHGLEDLLKDNMTSEGLYDIIHLKGEDIEIAFTHTNQYGEEYYSFVNGQHTT
                     QGGTHQTALKEHIARTIKEFYNKNQEYADIRNGLVAAIAIDVEEPMFESQTKTKLGSNN
                     MWPAAPQEHKPAGPTVNKYVGDFIKTEVDNYLHKNPLVAEVMLQKIQDSEKERKAIAGV
                     TKLARERAKKANLHNRKLRDCRYHLSDGKGKDQETESCIFITEGDSASGSITKSRDVNT
                     QAVFSLRGKPLNSYGLTKKVVYENEEFNLLQAALNIEDGIETLRYNKVIVATDADVDGM
                     HIRLLIITFFLQFFPDLIKKGHVYILQTPLFRVRNKKKTSYCYTEEERVKAIEELGPNP
                     EITRFKGLGEISPDEFKHFIGKDMRLEQVSLRKTDLVKELLEFYMGKNTMERQNFIINN
                     LVIEEDLAS"
     CDS             complement(13304..14440)
                     /locus_tag="ctg108_14"
                     /transl_table=11
                     /translation="MAITIKKVTTRRELERFIRFNYLLYKNNPYSVPDLFDDMLNTFNK
                     KKNAAFEFCEADYFLAYREGKIVGRVAAIINHKANQTWNKKEVRFGWIDFIDDAEVSDA
                     LIRTVEEWGKERGMTHIQGPLGFTDFDAEGMLIEGFDQLSTMATIYNYPYYPQHLERMG
                     FEKDADWVEYKIYIPDAIPDKHKRISDLIQRKYNLKVKKYTSAKKIAQDYGQAIFELMN
                     EAYQPLYGYSALSQRQIDQYVKMYLPILDLRMVTLITDADDQLLAVGISMPSLAEALQK
                     AHGRLLPMGWYHLAKTIFLKKYPKMLDLLLVAVKPEYQNKGVNALLFSDLIPVYQQLGF
                     EYAESNPELELNGKVQAQWEYFKTEQHKRRRCFVKGIK"
     CDS             complement(14591..15571)
                     /locus_tag="ctg108_15"
                     /transl_table=11
                     /translation="MDILFLVGGLLLILLGANGLTDGAASVAKRFHIPSIVIGLTIVAF
                     GTSAPELTVSISSALKGSADIAIGNVVGSNTFNTLMIVGCTALFAPIAITRNTLKREIP
                     LCILSSFALLICANDVLLDSSGENILSITDGLLLLCFFTIFLSYTFAIAKRDGSMKEPE
                     KEHLQEEDEIRLLPAWKSALYILGGLAGLIIGGNFFVDGASGIARGLGVSESIIGLTLV
                     AGGTSLPELATSIVAALKKNPEIAIGNVIGSNLFNIFFVLGCSASITPLRLTGITNFDL
                     WVLVGSSILLWLFGIFFGKRIITRVEGSILILCYIAYTAVLIYNL"
ORIGIN
        1 tattactact cactgcttta aattattctt atacaaaagt gttgcggaaa ttaggtatat
       61 gtcctttggc tactcctttt ttgtatgatg tcggggcagg taatagggca gaataagtcg
      121 gcagaatccc atagccatac ttgtaaaacg gtgctggcgt taaaaaataa tttgctttac
      181 gacctggcct tggctccgaa catagaagtg gagctgccat tgggaaagag gtggtctttg
      241 aatgttgagt acaaatgccc ttggtggtct gacagcggat gtaatttctg ctatcagctc
      301 ctttcgggag ggacagaggc gcgttactgg ttgggaaacc gccatacgcg cggaagattg
      361 tccggacact tcctgggagc atatgccgaa ggaggtacct atgattttca gttgaaaaag
      421 gagaagggat accgggggaa gtattacgca gctgcaggaa taacttatgg atacgtgcgt
      481 ccactggctc ggcatctggc gattgaattc agtgtgggca ttggatactt ggatacggag
      541 tacaggaaat atacttctta tggaaatgac ttggtttggg tcagtagtgg aaagtatcac
      601 tttatcgggc cgacaaaagc aaaaatttct ttggtatggc ttctaacgtc ggggagatga
      661 gtggtatgaa agatgcacgg catatgattc tctggctgtt cttcggactg ttgccaatgc
      721 tgggaagctg tgacttccgc gatatgctgg atgattatcc cgttagcgga gtacagatta
      781 aactggattg gaaaggggtg acggataagc tgccgcagac catgcggatt atcttctatc
      841 cgaaagatac tcaggggaga aaggttgaaa gttatctgcc tgccggaggg ggtgaggtga
      901 aggtaccgcc ggggaagtat gcggtggtgg cctataactt caatacggag agtatacaga
      961 tacggggcga cgagagttat gagacgattg aggcttttac gggacactgt acggggctgg
     1021 atgtacacga aaatatggtt tggtcgcccg accctttgta tgtggtggct ttggacgagg
     1081 tggaaatagg gcagagtgat gtggcgcttc cgttggactg gaagccggaa gcggtagtgg
     1141 accattattc ctttgatata aaggtggaag gatgggatag aatatcgagc atcatctgcc
     1201 atgtggacgg cttgaacgga agttacttta taggcaaccg tgcttgccat ttgagcgagg
     1261 tacctatatg tgtggataca aagcgtgaaa acgggctttt atgggggtat ttctccagtt
     1321 ttgtattact gaaagatacc aagacccgtg cggatagtcc tatgttgctg acactgaaga
     1381 ttgtgaaacg agataaaacg gttcaagagg tgaaggtaga catcacggaa gtgattgaaa
     1441 cagctcctcc ctcgggagga ggcgaagaag aacctgatgt gggcgttcct gggtcggaaa
     1501 tccatatcga agttcccgta ccggaggaca aggttgtggt ggatgatttg gaaccgggaa
     1561 ccgatgaagg agatggaggg attggtggcg atgtggacga ttgggatgat gagacggatg
     1621 tggagctacc agtgaattga tagcaaacag acaaataaat atattaactt taataacaga
     1681 caattatgaa gaaggtttta tttttggctt tggctgcagc agcagtaatg agttgctcgg
     1741 aaagtgagga gatagagaat gccggacaaa aggcagagat taaattggga acagtagtgg
     1801 gtaacactac gagagccaca gtgactgatt tgccggaatt gcagaaggta gggttcactg
     1861 tgtatgctta taatacggga gcgacagcaa tggcctccgt tgcgactttt gatgcgatga
     1921 aggaattcat gacagatgtt aaagtaacct atagtgctcc caactggagt ttgactgggg
     1981 gaacatatta ttggccaatg acggataact tgcagttctt tgcttacggg aatccgggta
     2041 ccggagcctt gacgtacaat caaccggctg ctggtgctat atatccttcc attacttata
     2101 cggtagcaga tgtagctgcc caaacggact tggtagccgc gaaagtgacg gatgcaacca
     2161 aggcatcaaa tgccagtggg gtatctttga aattcggcca tatactgacc caaataaatt
     2221 tcactgtcaa ggcagccgac gctttgactt ataaactgaa aacacttaca atatccggcg
     2281 tgcacaataa gggaacttat ggttttgatg attcaacatg gaagtcacaa gaaggaacag
     2341 ccacttatgc gcatacgatt gccggcagtg cattggaagt gaatacaacg ggtgtggaaa
     2401 tgaatgcagc ctggatgttg atgccccaga cgttggatac gaatgccaaa atcaatgttg
     2461 tctatgacat ctatgagaaa gacgttcttc ttgatactgt aacttccgcc attgacttga
     2521 atgatacaca agcctggggt gaaggcaaaa agatacgtta tacgctgacg ctggccaata
     2581 aggcggcaaa agtaaccttt gtacctgaag ttggtccatg gagtacggct gatgatacga
     2641 acgtggaaaa ataaaacggc actgtccgca ataaaaaact gaattacttc tattttattc
     2701 attccccgaa acttctttat gaaagttttc ggggaatgtt tcttttatga gtattattta
     2761 tctatttttg tcactgcaac aaacaaacaa atctacttgc cgatgcccaa ctcttctgct
     2821 tgcagaggta aaaaacaatg cgctcaatgt cccaaggctg tggacaatgc aataatatat
     2881 gcttcccacc ccagaggatt ccatctgccg gcgcgaaagt gtgaggaaaa tattataatt
     2941 ttcctgctga aaggagaagt gcttgtcaac agtaaggagt atgcgggaac tgtgttgcat
     3001 gcaggtgagt tcatccttca agctattggt tccaagtacg aaatacttgc catgacggat
     3061 gtggaatgcg tttgttaccg gttcagtaag cctgaattct tctgtgagga ccggtataac
     3121 catattatga aagaggttac ccctccattg atattctatc ctttgaccat tactcccgag
     3181 ttgcagctct ttctggaaag ttccaaggcc tatttgtccg aggagaagat ttgccgggaa
     3241 atactttgtt tcaaacggaa agaacttgct ttcattcttg gaaattacta ctccgactat
     3301 gagctttcca tgctgataca tcctcttgcc cagtatacta attccttcca ctactttgtc
     3361 ttgcagaatc atgccaaagt caagacggta gaggaacttg cccagttggg aggatataca
     3421 gtagctactt tccggcgtat attcaattct gtttttcatc aaccggtgta cgagtggatg
     3481 atggaacgga ggaaggaaag cgtggtttat gaacttcgtt atacggatgc ttctatatca
     3541 gagatttgct ataaatatgg ctttgaatcg ctgcctcatt tttccaattt ctgcaaaaag
     3601 aatttcgggg cttctccccg tagcttgcgt gccggcaatt tatctgaagt aaacggcatg
     3661 tcataaaaaa actcctccgg cggtttcccg gcagaggagt ctcttgtgat attaatcaaa
     3721 tatagtgaaa gctgagtgat aaatctgagc ttgctcaaaa ggtttatccg aagcgcatcc
     3781 tatattattt gcagaaagac cggattagtc tttcagtttc gcaatgataa agtcgcggtt
     3841 caggcgagca atgttgctga tggaaacatt cttcgggcat tcagcttcgc acgcacgagt
     3901 gtttgtacag ttaccgaaac cgagttcgtc catcttgctc aacatagcct tggcacggcg
     3961 caatgcttcc ggtttgcctt ggggcaacag gttcagctgg ctcaccttgg cagaaacgaa
     4021 cagcatagca gaaccgttct tacaagcagc cacacaagca ccacaaccga tacagctggc
     4081 agcatccata gcctcgtcag cgatgggctt cggaatcagg atagcgttgg catcctgggg
     4141 agcaccggta cgtacgctga cgtagccgcc tgcctgcata atcttgtcgt aggccgtacg
     4201 gtcgaccatc aagtccttga taaccgggaa accggcagag cgccacggtt caacagtgat
     4261 ggtatcgccg tcgttgaaac gacgcatata aatctggcaa gtcgtagcgc cggttgcagg
     4321 accgtgggga tgtccgttga tgtagagcga acacataccg cagatacctt cgcggcagtc
     4381 gtggtcgaat acaaccggtt ctttaccttc agaaatcagc tgttcgttca agatatccag
     4441 catttcgagg aatgaagtat cgcccgggat atctttcatt tggtatgttt caaaagcgcc
     4501 ttttgctttc ggacccttct ggcgccatac cttgagcgta aatgatatat ttttatccat
     4561 tttctttaat tctttaaatg ttcaacttcc cgattagctc ttgtagttac gagtctgtac
     4621 cttgattgct tcgtaaacca gcggctcttt cagcaatacc ggttcctttt cgtcagaacc
     4681 ctgatattcc cagcaagcca cgtagaagta gttttcatcg tcacgcttgg cttcgccttc
     4741 ttcagtctga tattcttcac ggaagtgacc gccgcagctt tcgttacggt tcagtgcatc
     4801 gtaagcaacc agctcgccca tagtgatgaa gtcgtacaga cggatagcct tgtcgagttc
     4861 tacattcata ccttccttgt cgcccgggat gaacagttct ttctcgaact ccttgcggac
     4921 ttctttcagc ttcttcagac cttccttcaa gccttcggcc gtacgtccca tacctacata
     4981 ttcccacata atgtggccca gttccttgtg gatagagtct acagacttct tacccttgat
     5041 gttcatcatc cagtcaatct tctcctgaac ggccttttct gcagctgcaa attcgggcag
     5101 gtcggtagag aaacggggaa ctgtaatctg gtcggccaga tagttctgga tagtgtaagg
     5161 caatacgaag taaccatcgg ccagaccttg catcagggcg gaagcaccga ggcggtttgc
     5221 accgtggtcg gagaagttac attcaccgat ggcgaacagt cccttgatgg aggtcatcag
     5281 ttcgtagtca acccagatac cacccatggt atagtggata gccggataaa tcatcatcgg
     5341 gttttcgtat gggctgacat cagtgatttc ttcatacata tcgaagaggt tgccgtaacg
     5401 ttgtgcaacg acatctttac ccagacggtt gatagcttcg gagaagtcaa ggaatacggc
     5461 aagaccggtg ttgttcacgc cgaagccctt gtcgcagcgt tctttggcag cgcggctggc
     5521 aacgtcacgc ggaacgaggt taccgaatgc cggataacgg cgttccaggt agtagtcgcg
     5581 gtcttcctcg ggaatatctt ttccttgcag tgtaccttcc tgcagtttct tggcatcttc
     5641 cagcttcttc ggaacccaga tacgaccatc gttacgcaga gattcggaca tcaaagtcag
     5701 cttagactgc ttgtcgccgt gaaccgggat acaagtgggg tgaatctgta cgtaagcagg
     5761 gttggcaaac caggcacctt tacggtagca agccattgct gcagagcagt tacatgccat
     5821 tgcattggta gaaaggaagt aggcattgcc gtaaccaccg gtagcgatta ccacagcgtg
     5881 ggcggcaaaa cgttccaatt taccggtaac gaggttcttt gcaatgatac cgcgggcacg
     5941 tccgtcaatg aggacaacgt cttccatttc gtagcgggta tacagtttca cagtgcctac
     6001 gttcacctgg cggctcaatg cagagtatgc acccagcaac agctgctgtc cggtctgacc
     6061 cttggcatag aaagtacggg atacctgagc accaccgaaa gaacggttgt ccagtgtacc
     6121 gccgtattcg cgggcgaaag gaacaccttg tgcaacgcat tggtcgataa tattgttgga
     6181 tacttcagcc aggcggtaaa cgttagcttc gcgggcacgg tagtcgccac cctttactgt
     6241 atcgtagaac agacggtata cagagtcacc gtcgttttgg taattcttag cagcattgat
     6301 accaccttgt gcagcgatgg agtgtgcacg gcgcggagag tcctggatgc agaagttgaa
     6361 tactctgaaa cccatttcgc ccagagaggc ggcagcactg gcaccggcaa gtccggttcc
     6421 tactacgatg atgtccagac gacgcttgtt ggcagggttc actaattttt ggtgagcttt
     6481 ataattggtc catttctcag ccaccggtcc ttccggtatt ttagaatcta tcttagtcat
     6541 aatgcaattt acaatttagt catttacaat ttgaatttag caagcgccgc acaatgattt
     6601 tgcaaagaat acgacaacta ccagagcgaa gcagaggaca acgatagtag aatagatgtt
     6661 ggagatacat ttccaacggt taatccatac tttgttgttc cagcccaaag actgcatgga
     6721 gctccagaaa ccgtgagtga ggtggaacca caatgcgccc agccaaacga ggtaaagcac
     6781 tacgaatacc ggattgctga aggtgttttg aatgtgatag acaccgttgg ctgcatatgc
     6841 cagcgtgagg gtgtcggcat gcatgcccat gttgtgcatc aactcgggaa gctgcatttt
     6901 agcccagaag tttaccaggt gcaggcccaa acccacgatt acgatgatac ccagtacgag
     6961 catgttctga gaagcccatt ccacagtctt gggcttttcc gtaacggcat aacgttcgct
     7021 accacgtgcc ttacggttct gcatagtcag ccagaaagcg tagatgatgt ggatgatgaa
     7081 taaggcagcc agacctaccg tagccaccaa tgcgtaccag tttgctccca ggaactcaca
     7141 aaccatgttg tagccattag ccgagactaa tgcaaccagg ttcatcgcca tgtgaaatgt
     7201 cagaaacagg acaagggcga taccggtaac gctcatcacc actttccttc ctacagatga
     7261 attacttaac cacataaatg attgaattta agttatttaa tagtttgaaa atttgttcta
     7321 tcaggatact tctgtaaatg tttcgcaaaa ataggagaaa tccagcgata aagcaagcga
     7381 ttaaagaaat aattccgtaa tccggcagaa tgcgaagttt acggacaagt aaaaggttta
     7441 ctcgtcctcc tggtctttgc cttgctcttt gcagataatg gaaatctttt ctccgtttgc
     7501 tgaacgtttt ctcagggcgc ggggcgtgtc tccgaaagag tctttgcaga agtgggcaaa
     7561 gtgggatagg gaatcaaagc catagcgggc gctgatgact gaaatgcgtt gtttggtgta
     7621 ttgcaggtcg ttcagaattc cttcacgttt cttgtccaga atccattcat agaccgggac
     7681 cccatacata tttttaaaca gacggcggaa tgtggtggtg gtatatccac cgaggtgggc
     7741 aaactcttcc acattcttca ccttgtcgta gttctgcatg acgaaatatt ggaagctttc
     7801 cgtataagtg ctgatggggt agaagaatgt actgatttgg tgtagcggat agtagcatgt
     7861 caatatgtat accaattcct ggcatttcat ttcaatgtat ttgctgcacg catagggttg
     7921 ctcgttgagg tagcaggcaa ggcttttcag gagcccttcg agcatggaaa tcgcggtaag
     7981 cggggtataa gtcaaggggg cttccgagcg tttcagtatc tccttgtagc gctcttcgca
     8041 aatcagagga agctcggtga accaatagac aatatattcc acttcggtca aagccaggag
     8101 ttctactttg gagccgatgg cttgcaagat gagctggcgg ctttggagag tggtgcccgg
     8161 atattcgtca ctgtttacaa gtaattcacc tttcagcata aatatcatgc agttctgtgt
     8221 gcacttttca gcagagaaat gttgtccctt ggggtagtgg cggtaaacca atactccttc
     8281 tgatttttgg ggacatacca tacaatcaat ctgtcggttg cagcaagttt ccagtctcat
     8341 gaaatgatta gcgaattatt ataaatgtgg caacaaagat agaatttttt tgtgaaaact
     8401 ctatctattt gtcctatctt tgcgtcaaac taatataaag gacttatgaa aaaggctatt
     8461 ttttttgtat attttatctg ccttgttgta tccggtcttt cggcacagaa ttgggatatt
     8521 aacactttgc atcgggttaa cagttgggat ggcaagtttg tccgtaacta taataagata
     8581 atttcacgtt cggagcccta tgttgctgtc ggtgttccgg tggcgatggc ggttgccgct
     8641 tggataaaac atgataaggg tttgctgaaa gatgcggtct acgtaggtac aagtgtagcg
     8701 ggggcttttg ttgtgactta tggaatgaaa tatctggtgg accgtgagcg tccttatgat
     8761 aaatatcccg acagagtgca tgcatatagc catgaaggca gcccgtcttt tccttccgga
     8821 catacggcga cggcttttgc ccttgccacc tcgctcagtg taaagtatcc taaatggtat
     8881 gtgatagctc cgtctgccct gtgggcttgt tccgtgggag tttcccgtat gaacgaggga
     8941 gtgcattatc cgtcagatgt gttggcgggg gctgcaatcg gtgctggatg tgctgtggtc
     9001 aacatctacg tcaacaagtg gctgaataag tggctgttcg gagaatgatt ttaggcgcga
     9061 attacgcgga atacgcggag ttagataaac taaatccgca taatccgcgc ctaagtttgt
     9121 ttcaagtcgg ctattggata atagtgctgt agatgccttc gttcagcact tttagagctt
     9181 gctgcacgct ctggttcgtg ctgttcatca cttggaagta ttcgttcatg tcccataggt
     9241 cacgggctat caaggcttta agttgtgtct tgatgagcgg tagggattgg ttgtactgtt
     9301 tctcgtcaaa cttgattttc tctttgtcgg caagcgtacg tatttcggca aggaagttat
     9361 cgtctatctc gaacttctcg ttgaaggctt cgaatttctt gtatttgttc tgcaactcct
     9421 tccggtgctt ctcgatgtag ccggtagtgg ctttgataac cacgcctttg gctacgaggt
     9481 tgcggtgata gtctgtgtac tgggtagtgt cgatggggac gaagaagtcg ggcatgatac
     9541 ctccacctcc gtaaacggta cgtcccatac gcttggtctg tgctttcagg gagtcggcaa
     9601 aatggatact gtccgcatga atcatttctc catgattgaa gcggtctatc agttcctggt
     9661 tatacttatc ctgactgttc tcgccggtta ggcggctgtc gaggttggcg gtgctgtcgt
     9721 aaggcttctg gatacaacgg cccgaaggag tatagtagcg ggcgatagtg aggcgaatca
     9781 tggaaccgtc cggcaggtcg ataggacgct gtactaatcc cttgccgaag gtgcggcgtc
     9841 ctactaccac gcctctgtcc cagtcctgga tggctccggt cacgatttca ctggcagaag
     9901 cggagtactc gtccaccaat atgatgagac ggccgttctt gaagttgccc gtacctttgg
     9961 caaagaaatc actgcggcgt gcggcccttc cttcggtgta gacgatgagt tctttttgct
    10021 tcagaaattc gttggcaagg tcgatggcgg cattcagata ccctcctcca tttccttgca
    10081 ggtcgaggat gaggtctttc attcctttct tttgcaggct tttcagggct tctgcaaact
    10141 cttcggcggt ggttgccccg aagcggttga tacggatata gccggttttg ggttgtatca
    10201 tgtaagatgc gtccaggctg aggatgggaa ttttgtcacg cttcacggtg aagtacagct
    10261 ggtcgtccac gccacggcgc acgatggtga gtttcacttc cgagtctttc ggtccgcgca
    10321 ggcggctcat aatatcttcc gtgctcattt ttactccggc aatggcgctg tcattgacgg
    10381 ctacgatacg gtcgccggca aggatgccca ccttctcgga aggtccgttg ctcacgggtt
    10441 gtatcacaag cagggtatct tctatcatct gaaactgtac gccgatgccc tcgaaattgc
    10501 cttgcaacgg ctcgttcatc ttcttcactt cttcggcgtt gttgtaggtg gagtgcgggt
    10561 cgagttgtgc cagcatcttg atgatggctt cttccaccag cttgtcttca tccaccttgt
    10621 ccacataaag gttggtgatg gcaaactctg ccatttgcag tttgcgcagg gcttcattgt
    10681 tcggcttttg cgcttgtgcc gtcaccgcgc atatacatat tataatagta aatagttttt
    10741 tcatcatttc cattttaatc cctaatcctt tatccttaat ccctaatcct ttatccttaa
    10801 tccctaatct ccattccctc cggtatgaac atgcttatgt ccttgccgta ttgcagcagt
    10861 tcgcgcacgg tggtggaact gacgcaggta agttccggct cggtgaagag caggatggtt
    10921 tctatgccgg tcagtttgcg gttgatgtcg gcaatggttt cctcgtattc gaaatccttc
    10981 acggtgcgta tgccgcgtat tatcagactg gcatctacct gccgggcaaa gtcgatagtc
    11041 aggcagtcat aggactgcac aatgatgcgc ggctcgttcc ggtagtagtc tcgtatcatt
    11101 tgttcgcgct tttccaaggg gaaatacgta ttcttatttt cattgatgcc gatgcctatg
    11161 acgatttcgt ctataaaagt cagtgcacgg ctcactaccg aagagtgtcc gatagtaaac
    11221 gggtcgaatg ttcccggaaa gatagctctt ctcatgatgc caaatcttct tctataacca
    11281 agttgttgat aataaagttt tgtcgttcca tggtattctt acccatgtag aattccagca
    11341 gctcttttac gaggtctgtc ttgcgcaggg acacttgttc cagacgcata tccttgccga
    11401 taaaatgctt gaactcgtcg ggcgagattt ctcccagacc tttgaatcgg gtgatttcgg
    11461 ggttgggacc cagttcttca atggctttca cacgttcctc ctctgtatag caataacttg
    11521 tcttcttttt gttgcgcacg cggaagagag gggtttgcag gatatataca tgccctttct
    11581 ttatcaggtc ggggaagaac tgcaggaaga aggtgatgat gagcaggcgg atgtgcatgc
    11641 cgtccacatc ggcatcggta gctacgatga ctttgttgta gcgcagtgtc tctatgccgt
    11701 cttctatatt caaggctgct tgaagcaagt tgaattcttc gttttcataa actactttct
    11761 tggtgagtcc gtaggaattt agcggtttac cacgcaggct gaatactgct tgggtattca
    11821 cgtcgcggct cttggtgatg gaaccgctgg cggagtctcc ctcggtaatg aagatgcagg
    11881 attcggtttc ctggtctttg cctttaccgt cactcaagtg gtagcggcag tcgcgcagct
    11941 tgcggttgtg caggttggct ttcttagcgc gttcgcgtgc cagcttggtg acgccggcaa
    12001 tggctttgcg ctctttctcg gagtcttgta tcttttgcag catcacttcg gccacaagcg
    12061 ggttcttgtg gaggtagttg tccacttccg tcttgatgaa gtctcctacg tatttgttca
    12121 ccgtggggcc ggcgggcttg tgttcctgcg gcgcggcagg ccacatgttg ttgctgccca
    12181 gtttcgtttt ggtctggctc tcgaacatgg gttcctccac gtcgatggca atggcggcta
    12241 ccagtccgtt gcggatgtcg gcatattcct ggttcttgtt gtagaactcc ttgatggtac
    12301 gggcaatgtg ttccttcaag gcagtctggt gtgtgccgcc ttgggtggtg tgttgcccgt
    12361 tgacaaagga gtagtactct tcgccgtatt ggttggtgtg tgtgaaggca atctcgatgt
    12421 cctctccttt taggtggatg atgtcgtaaa ggccttcgct ggtcatgttg tctttcagca
    12481 agtcctccag cccgtggcgg gaaacgatgc gctggccgtt gtaaatgaag gtgaggcccg
    12541 tattcaggta ggtgtagttg cgcaacaggg tttctacgaa ctggttctgg aaggaatagt
    12601 tcaggaagag tgtggcgtcc ggttcgaaga agatataggt tccgctttct tctgtcgagt
    12661 cttcggtcac atcactcaac agcgttcctt tctcgaagat ggcggtacgt actttgccgt
    12721 cgcggtaact gcgtacctcg aaacggctac tcagcgcatt gaccgccttg atgcccacgc
    12781 cgttcagtcc gacacttttc ttgaaagcct ttgaatcata tttacccccg gtattcagtt
    12841 tgctgaccgc ctctaccagt ttgccttgcg gaatgcctcg tccatagtcg cgtacgctga
    12901 cacgcagact gtcttctata gtcacttcta tacgctttcc ggcacccatc ttgaactcgt
    12961 cgatgctgtt gtccatcact tctttcagca acacatagat gccgtcatcg ttctgtgagc
    13021 cgtcgcccag acggcctatg tacataccgg aacggacacg gatatgctcc atgtcgtcca
    13081 ggtggcggat gttgtcgtcg gtatattcca cgctggaaac ggggctctct gtgatattgt
    13141 tgtctgcttc ttccagcggc agggtcatat tgttgttatc ttccataagt acgttattcc
    13201 ttcatattgc gcattgcgac aaaggtaatg agaaattcgg gggttcgcaa aaaaataatg
    13261 tcttttatgg acttctgaca agcttatatt ctggatttag aacttatttt attcctttca
    13321 caaagcatct tctccgttta tgctgttccg tcttgaagta ctcccactgc gcttgcacct
    13381 tgccgttcag ctccagctcc ggattactct cggcatactc gaaaccaagt tgctgataga
    13441 cggggataag gtcggagaac aacaatgcat ttaccccctt gttctgatac tccggtttca
    13501 cggcaaccag cagcaaatcg agcatcttgg gatatttctt caagaagatg gtcttggcca
    13561 ggtgatacca acccatagga agcaggcgcc cgtgggcttt ttgcaacgct tcggcgagtg
    13621 acggcatgga aatgcctacg gcaagcagct ggtcatcggc atcggtaatc aatgtcacca
    13681 tgcgtaggtc gaggatgggc aggtacatct tgacgtattg gtcaatctgc cgttggctca
    13741 gtgcagaata gccatagagt ggctgatagg cttcgttcat cagttcgaag atggcctgac
    13801 cgtagtcttg ggcaatcttc ttggcagatg tgtatttctt taccttgagg ttatacttgc
    13861 gctggatgag gtcggagatg cgcttgtgct tgtcgggtat ggcgtcggga atgtagattt
    13921 tgtactccac ccaatcggca tccttctcaa agcccatgcg ttccagatgt tgcggatagt
    13981 agggatagtt ataaatggtg gccatggtgc tgagctggtc gaatccttcg atgagcatac
    14041 cttcggcatc gaaatctgtg aatcccagcg ggccttgtat atgtgtcatt ccccgttctt
    14101 ttccccattc ttccacggtg cgaatcaggg catcggagac ttccgcatca tcgatgaagt
    14161 ctatccagcc gaagcggact tcctttttgt tccaggtttg gtttgccttg tggttgatga
    14221 tggcagctac acgtcctacg attttacctt cccgataagc caggaaatag tcggcttcac
    14281 aaaattcgaa tgcagcgttt ttcttcttgt tgaaggtgtt gagcatgtca tcgaaaaggt
    14341 cggggacgga ataagggttg tttttgtata gcaggtagtt gaaacggata aagcgctcca
    14401 gttcccgtct tgtggttact ttcttgattg taattgccat agttgttcaa tattgagacc
    14461 acaaaggtaa tgcaaactga gagcagaaca aaataagctt gcttattttt tatgccgagg
    14521 tacagcttgc cttatttaaa aatacgtgat aatctttaaa ataccgcgta gggtgtttgt
    14581 aaatttgctg ttagaggttg tatatcagta ccgctgtgta ggcaatgtag cagagaatca
    14641 gaatgcttcc ttccacccgg gtgatgatgc gtttcccgaa aaagataccg aacagccaaa
    14701 gcaggatgct ggaccctacg agtacccaca aatcgaaatt ggtgatgccc gtcagacgca
    14761 gtggagtgat ggaggccgaa caacccagta cgaagaatat attgaagaga ttacttccga
    14821 tgacgtttcc gatggctatt tcggggtttt tcttcaaggc ggctacgatg gaggtggcga
    14881 gttcgggtaa tgaagtgccg cctgctacga gcgtgagacc gatgatggat tcgctgacac
    14941 ccaatccgcg ggctatgccg ctggcaccgt ctacaaagaa attacctccg atgatgaggc
    15001 cggcaagtcc gccgagaatg tatagggcgg atttccacgc gggtaacagc ctgatttcgt
    15061 cttcttcctg taagtgctcc ttttccggtt ccttcatact tccatccctt tttgcaatgg
    15121 caaaagtata actcagaaaa atggtaaaga agcatagcag caataggccg tcggtgatgc
    15181 tgagtatgtt ctccccactg ctgtccagta agacgtcgtt ggcacaaatc agcagggcga
    15241 aggatgaaag gatgcaaagg ggtatttcgc gtttcagtgt gttacgggta atggctatcg
    15301 gggcaaaaag ggccgtacaa cccacaatca tcagggtatt gaacgtattg cttcccacca
    15361 cattgccgat ggcaatgtct gcactgcctt ttagggcaga ggatatgctg acggtgagtt
    15421 ccggtgcgga agtaccgaag gcgacaatgg taagcccgat gacgatggac ggtatatgga
    15481 aacgtttggc aacggatgcg gcaccgtctg tcaagccatt ggcacccaga agaatgagga
    15541 gcagtcctcc gacaagaaac aatatatcca taggtatgtc aattttgagt acaaagataa
    15601 tgcaaaccgg atacagaact ttcatgtttg catgaaaaag ttatgttgat taggatagga
    15661 agttaaaaac attccgtatg tttgaagcat ttattggcta tatttgcata attaaagaat
    15721 caaatcaaga agtttatata tgaaggttat ccgtgctttc tgtctttgtt ggctgttgat
    15781 gctggcagac ggagtgtcag ctcagttggt agataaagtg ctcagtgttt taggtgagga
    15841 tagtgtgggg agtgtcacag tggcaaggac tgactccgat tcgattcagt tgtcgcttgt
    15901 ccggcaggag ttggaaacag cccggctgaa tgaggcgaac ctgcggatgg aaatggagca
    15961 gatgaagttg gcgggctatg cggccgattc ggtgaagctg gcattgcaga aacaacgcat
    16021 tgattcgttg cggacggtga caccgggtat tccggtggtg gtggagaagg acactttgtt
    16081 ctatctgtat gccaagcgtg gagggcatac gccccaacag cgagccaaag atgtaagcaa
    16141 cgtcatcgaa gcattgggca cgcgtttcaa tctgcgtccg gactctgttt atttagagag
    16201 tacggatatt gttacagact tgatgtatgg cgaaaaggtc atcatttcct ttaccgatca
    16261 ggatgctttg tgggaaaact gtacccgcga ccagctggcc gccagcaaga ggcatgtcgt
    16321 ggtggacaaa ctgaaagcca tgcagaagga gcatagcttg tggcagttgg gtaagcgtat
    16381 cttgtacttt atcctggtgc ttgtgggaca gttcttcttg ttcaagttta ccaactggct
    16441 gttcagaaaa ctcaaactac gcattcagaa gctgaaggat accaagctga aaccgatctc
    16501 tattcaggat tatgaattgc tggatacgca gaagcaggtc aacctgctgg tgtttgttgc
    16561 caacctggtg cgttatgtag tcatgctgtt gcagttgctg ctgacggttc cgttattatt
    16621 ctccattttc cctcagacca agagcttggc ttatacatta ttctcctaca tctggaatcc
    16681 tataaaggtc atcttgaatg gaatagccga ctatataccc aatctgttca ctatctttgt
    16741 gatatgctat gcggtgaagt atctggtcag actggtgcgt tatcttgcca atgaggtgca
    16801 ggctgaacgg ctgaagataa acggcttcta tccggattgg gccattccta cctatcatat
    16861 tgtgcgcttc ttgctttatg cgtttatgat tgccatgatt tacccttatc tgccgggttc
    16921 caagtcggga gtcttccagg gaatctccgt gtttgtcggc ttgattgttt cgctcggttc
    16981 cagtacggtt atcggcaata tcattgcagg actggtcata acctacatgc ggcctttcaa
    17041 gctgggtgac cgcatcaagc tgaacgatac tacgggcaac atcattgaga aaacaccgct
    17101 cgtcacccgc atccgtactc cgaagaatga ggtggtgacc attccgaact ctttcatcat
    17161 gtcttcccat acggtcaatt acagccagtc tgcccgtgag tatggattga ttatccattc
    17221 ggaggtcagt attggctacg atgttccgtg gcggaagaca catcagctgt tgata
//
