LOCUS       c00129_gnlPro..        15294 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CPPDHDIG_129.
ACCESSION   c00129_gnlPro..
VERSION     c00129_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:48:57
            Original ID  :: gnl|Prokka|CPPDHDIG_129
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15294
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15294
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[59:5294]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      60..5294
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15294
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15294
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(60..644)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg129_1"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.4e-64, bitscore:
                     207.3, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIMEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETALGMSAA
                     VAFVLTIATIVTFLIQKYVLDAFDLGYLQTITFILVIAALVQMVEIILKKVSPSLYQAL
                     GVFLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTALGFGLALTLFAGLREQMSLVS
                     VPKGMQGTPIALITAGLLAMAFMGFSGVVKI"
     CDS             complement(732..1298)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg129_2"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.3e-70, bitscore:
                     227.0, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICS
                     NVVISAIKNLIPDMVRIPSFIVVIASFVTLLQMIMQAYVPALYATLGLFIPLIVVNCIV
                     LGRAEAFAAKNNPVASLFDGLGMGLGFTIALTLLGAVREFLGTGKIFNLSILPEEYGML
                     VFVLAPGAFIALGYLIALINSMKKN"
     CDS             complement(1333..1968)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg129_3"
                     /sec_met_domain="FMN_bind (E-value: 2.9e-24, bitscore:
                     75.7, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKEPIAQANAKTLSDAVSAVVPG
                     FDNDPIAEKKMQEVNGVQYSVYPATKGGEYIGAAVEAVAMGFGGELKVLVGFDAEGKII
                     DYSLLSHVETPGLGSKAADWFKKGNKGDITGMNPGEAALTVSKDGGKVDAITASTITSR
                     AFLNAVNAAYAAYAGQETADGTTGATQKNVEQPADSAAPEAVDTLSAK"
     CDS             complement(1995..2987)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg129_4"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 2.7e-119,
                     bitscore: 387.9, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKLIVSLSPHVHGGDSVKKNMYGVLIALIPAFLVSLYFFGLGAL
                     IVTATSVAACLFFEWAIGKFLMKKETTTITDGSAIITGVLLAFNLPSNLPIWIIILGAL
                     FAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPAVGQLTAYTDATTAATPLA
                     IMKGVINGAPGMSLSDLPGAFDLLIGNNGGCLGEVSALALLLGLFYMLWKKIITWHIPV
                     SILVTVFVFSGIMYLVNPELYVSPVVQLLSGGLMLGAVFMATDYVTSPMSHKGMLIYGV
                     CIGLLTVIIRLFGAYPEGMSFAILIMNAFTPLINTYVKPKRFGEVAKKK"
     CDS             complement(2994..4331)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg129_5"
                     /sec_met_domain="Fer4_10 (E-value: 2.5e-09, bitscore: 27.3,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 5.2e-16, bitscore: 48.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.5e-49, bitscore:
                     158.0, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 6.2e-30, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.8e-05, bitscore: 14.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIIKAEIPAKAAILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEPGGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEESIDRSETLVKECSLTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPAFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVQYPQGGEKQLIDAVISRQVAAGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSLAKPSNFLARIGTPMKQLIEACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPTAKGSSGILIMNEKEAKRGEVQPCIRCAKCVGACPMGLEPYLLATVSAHGDFERV
                     EKEDIMSCIECGSCQFTCPSNRPMLDYIRLGKGKVGAMIRARQAKK"
     CDS             complement(4392..5294)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 37.6; E-value:
                     8.3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg129_6"
                     /sec_met_domain="Fer4_7 (E-value: 8.3e-13, bitscore: 38.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.2e-09, bitscore: 27.9,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 6.6e-09, bitscore: 25.8,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 6.8e-09, bitscore: 25.8,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.5e-11, bitscore: 34.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9.6e-06, bitscore: 16.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVILIAVISLGVIALVSAAILYVASKKFAVYEDPRIAQVAEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKLCPVGGQPVMTKIAEILGLDAAAAEPMVAVV
                     RCNGTCANRPRVNQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEEKCTACGACAKACPKSIIEIRPQGKKSRRIYVQCVNKDKGAVARKACTVACI
                     GCGKCVKVCPFEAITLENNLAYIDPNKCKSCRKCEEACPQNTIIALNFPPRKPKADDAA
                     PQVKVAAPKAEVETPKAEV"
     CDS             complement(5332..5751)
                     /locus_tag="ctg129_7"
                     /transl_table=11
                     /translation="MANTIKHQGIVENINGSHLQVRIIQTSACASCSVKGHCTSADTKE
                     KLVDVADANAASYQPGDRVWVTGELSMGVMAVLFAFIFPFLILIISLFVFMAIWNDELR
                     SALCSLALLVPYYYILWLNKLRMGKKFSFSVRPMN"
     CDS             complement(5982..7382)
                     /locus_tag="ctg129_8"
                     /transl_table=11
                     /translation="MISSSVMARNTLDTASKNSGQETTAKADTLPDIMKEYMILKLKPE
                     GMGYRLDTVSILYERYIGVLDYLNDPTTPERYIPSNPNYYRLFLPLTYYYAPMRRLSKV
                     DWHFQVPDTVPALTREMLPFDTLSFTSKDRANKLVDRTLLNTYVNCPNLVVMTEKEVMK
                     GKIFKDNIEKEVSSKPSVVKLFAQENMVGVKEEADVIIHKPNWWVTGGNGSLQITQNYI
                     SDNWYKGGESTNAVLANLQLFANYNDREKVQWENLLDAKLGFSSAPSDEFHNYLVSTDQ
                     LRLYSKLGIQAASKWYYTITTEFKTQFCNGYKANSEELVSAFFAPADWSSSIGMDYKLK
                     KQKFSLSVFIAPLTYMLRYVGNKGVNEVSFGLEEGKCVKHNFGSQIQPTLSWTIIPSIT
                     LDSRLDFQTSYEWTRIEWENTVNFVLNRYLSTKLYVHARYDDSAKPTEGDSYFQVKELL
                     SFGINYKW"
     CDS             complement(7454..7660)
                     /locus_tag="ctg129_9"
                     /transl_table=11
                     /translation="MPRAYTACRSGCALLPSVHVELKKRKIIKKRGSRESFDETIIKKY
                     DFIEESPSCLFLMAFLCFLNILS"
     CDS             7692..9311
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg129_10"
                     /sec_met_domain="GATase (E-value: 9.5e-55, bitscore: 175.4,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGETKYIFVTGGVASSLGKGIISSSIGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLGIQTTKANNITTGRIYKSVIDKE
                     RRGDYLGKTIQVIPHITDEIKRNVKLLGNKYKFDFVITEIGGTVGDIESLPYLESIRQL
                     KWELGKDALCVHLTYVPYLAAAGELKTKPTQHSVKELQSAGIQPDVLVLRTEHELSTTL
                     RKKVALFCNVDENAVVQSIDAPTIYEVPILMQSQGLDVTILKKMGLPVGDTPGLGPWRA
                     FLERRHKAEETAPLHIALVGKYDLQDAYKSIREALSQAGTYNDRKVSVDFVNSEKLTDE
                     NVAEALKGMAGVLIGPGFGERGVAGKFVAIKYARTHDIPTFGICLGMQCIAIEFARNVL
                     GYADANSREMDEKTPHNVIDIMEEQKSITNMGGTMRLGAYECVLQKGSKAYEAYGTEHI
                     QERHRHRYEFNNSFKEAYEAAGMKCVGINPESDLVEIVEIPALKWFVGTQFHPEYSSTV
                     LHPHPLFVAFVKAAIENENEKK"
     CDS             9343..11196
                     /locus_tag="ctg129_11"
                     /transl_table=11
                     /translation="MDKNTITGLVLIAILLVGFSFLSRPSQEQLEAQQRYYDSIAQVQQ
                     READLKAKAEAALANESGAEASVDSTALFFDARQGTNSQVTIQNNLAEITVDTKGGRIA
                     SATLKEYMGQDKTTPVTLFSGNDASMNFLFYNKKETIQTEDYYFTAVNRTDSTVTMRLS
                     ADSNSYIDFTYRMHNDTYLIDFTIQAVNMEGKLAATNNYVDIEWSQRARQIEKGYTYEN
                     RLAELTYKITGEGTDYLSANKNDEKEVPERLDWIAFKNQFFSSVFLADADFEKTKLSSK
                     METQGSGYIKDYSAEMSTKFDPAGKEPTQLFFYFGPNHYKTLTALDKGRDEKWELNRLV
                     YLGWPLIRWINKWFTINIFDWLSSWGLSMGIVLLFMTLIVKAVVFPATWKTYMSSAKMR
                     VLKPKIDEINKKYPKQEDAMKKQQEVMGLYSQYGVSPMGGCLPMLIQFPILMALFMFVP
                     SAIELRQQSFLWADDLSTYDAFINFPFHIPFLGSHLSLFCLLMTVTNILNTKYMMQQQD
                     TGANPQMAAMKWMSYLMPIMFLFILNDYPSGLNYYYFISTLVSVVTTLIMRKTTNEEAL
                     LAQLEANKKDPKKMKKTGFAARLEAMQKQQEQMMKEKQNKK"
     CDS             11298..12629
                     /locus_tag="ctg129_12"
                     /transl_table=11
                     /translation="MQTKYTYKQIWLIAYPILISLLMEQLIGMTDTAFLGRVGEVELGA
                     SAIAGVFYMVIFMVAFGFSIGAQILIARRNGEQQYKEIGDLFYQGIYFQVGMATVMFLL
                     SYCFSPIILKRIVASEHIYEAATSYLHWRVFGAFFSFSAVMFRAFFLGTTQTKTLTLNS
                     IVMVLSNVVFNYILIFGKFGFPALGIAGAAIGSSLAELVSLLFFILYTRSRIDCCKYGL
                     DRIPKFRLDVLKRMLNVSFWTMIQNFFSLSTWFLFFLYVEHLGERSLAVTNIVRNVSGI
                     LFMVLMAFASTCGSLVSNLIGAGHSDCVAGTIRQHVRIAYVFVLPLALLFALFPKLILG
                     IYTDIPDLQDAAVHSLWVMCSTYLFLVPANVYFQAVSGTGNTRTALGMELATLVIYTAY
                     ITYIILILQLDVAICWTSEMVYSSFILIFCWLYIKRGNWQGRKI"
     CDS             12691..14790
                     /locus_tag="ctg129_13"
                     /transl_table=11
                     /translation="MSAAMTLASCGGTKDAGQQQDAATLIQRSDIKIEGKRMTPEALWA
                     MGRIGSVAVSPDEKQIAYTVSYYSVPQNKSNSEVFVMNADGSDNTQITHDAWQEGQPTW
                     FKDGKKLAFLCNESGSSQVWEMNPDGSGRKQLTQYEGDIEGFSFSPDGKKLLFIAQVKT
                     VKSTADKHPDLPKATGIIVTDLMYKHWDEWVTTAPHPFVADFDGNAISNVTDILEGEPY
                     ESPMKPWGGIEQLAWSPSSDKVAYTCRKKTGLAYAISTNSDIYIYDLASKETKNITEEN
                     KGYDTNPQYSPDGKYIAWQSMERDGYEADLNRLFIMNLETGEKRFVSKAFESNVDAFLW
                     NKDSRSIYFIGVWHGETQIYNIDLVGNDKLTQLTDGMHDYASLALCGNKIIAKRHSMSM
                     GDEIYAVNSARNGDAFAEAVQLTTENKQIYDQLEMGKVEARWMKTTDGKQMLTWVIYPP
                     QFDPNKKYPTLLFCEGGPQSPVSQFWSYRWNFQIMAANDYIIVAPNRRGLPGFGVEWNE
                     AISGDYGGQCMKDYFTAIDEMAQEPFVDKDRLGCVGASFGGFSVYWLAGHHDKRFKAFI
                     AHDGIFNMEMQYLETEEKWFANWDMGGAYWEKNNATAQRTFANSPHLFVDKWDTPILCI
                     HGEKDFRILANQAMAAFDAAVMRGVPAELLIYPDENHWVLKPQNGVLWQRTFFEWLDKW
                     LKPAK"
ORIGIN
        1 tattactact cactgcttta aattattctt atacaaaagt gttgcggaaa ttaggttctt
       61 taaatcttca caacccccga aaagcccatg aatgccattg ccagcagtcc ggcagtaatc
      121 aaagctatcg gagtaccctg catacctttc ggtacactaa ccaggctcat ttgctcgcgc
      181 aggcctgcaa acagtgtcag tgccaagccg aaaccaagtg ccgtggagaa tgcataaacc
      241 actcccgtca gcaaatcata atctttttgg ataacaagga tagccacacc gagaatacag
      301 cagttggtag taatcaacgg caggaacacg cccaaggcct gatacagaga aggagaaact
      361 ttcttcagga taatctctac catctgcacc aatgcggcaa tcaccaggat aaaggtaata
      421 gtctgcaaat agcccaaatc aaaagcgtcg agcacatact tctgaataag gaatgtcacg
      481 atagtggcga tggtgagcac gaatgccacc gctgccgaca tgcccaatgc agtctccact
      541 ttcttggaaa ctcccaagaa cgggcaaatt cccaagaatt gcgacaatac gatgttgttt
      601 acaaagattg ccgagataaa tatcaatata tattccataa tcattaaatt aagaattaaa
      661 aactaaaaat taaaagcccg gcagcttacc gccgatacgt tctcaatttt ttcattttta
      721 atttttcatt attaattctt cttcatactg ttgattaaag caatgagata gcccaatgca
      781 atgaatgcac ccggagcaag gacaaatacc aacatgccgt attcttcggg aaggatactc
      841 aagttgaata tcttgccggt tcccaggaac tcacgcacgg cacccagtaa tgtcagtgca
      901 atggtaaagc ccaagcccat gcccagaccg tcgaacaagg aagccaccgg attgtttttg
      961 gcagcaaatg cctcggcacg tcccaatacg atacagttta caacaatcag cggaatgaac
     1021 aggcccagtg tggcgtacaa tgcaggaacg taagcttgca ttatcatctg caacagtgtc
     1081 acaaatgatg ctatgactac aatgaatgaa gggatacgca ccatatcggg aatcagattc
     1141 ttgatggcag aaatcaccac attggaacat atcagcacga acattgtagc cagtcccata
     1201 cccataccgt taatggcaga ggaagtggta cccagtgtag gacacatacc cagcaggagt
     1261 acaaacgtag gattctcttt gataatcccg ttcatcataa ctttaaaatt attcatatct
     1321 tctactcctt tcttatttag cgctgagtgt atccacagct tcgggagctg cggaatcagc
     1381 aggttgttca acattctttt gagtagcgcc ggtagtgccg tcggcagttt cctgaccggc
     1441 ataggcagca taagccgcat tcactgcatt caaaaaagca cgtgaggtga tggtagacgc
     1501 tgtaatggca tctactttac caccgtcctt gctcactgtc aatgcagctt cacccggatt
     1561 catgccggtg atgtcacctt tattgccttt cttgaaccag tcggcagcct tggaacccaa
     1621 ccccggagtt tccacatgcg acaacaagga gtagtcgatg attttgcctt cagcatcgaa
     1681 accgaccaac actttcagct caccgccaaa acccatggca acagcttcca cagcagctcc
     1741 gatatattct ccacctttgg tggcaggata tacagaatac tgtactccgt ttacttcctg
     1801 catcttcttc tcggcaatgg ggtcattgtc gaagcccgga accaccgcac ttacggcatc
     1861 gctcaaggtc tttgcattgg cctgcgcaat gggctccttc gtcaattcgt ttacataagc
     1921 cagcaacgct acggagattg cggtaacgcc cgtaagtacc agcaacatat tcttcaagga
     1981 tgattctaac tttttcattt cttcttcgct acctccccaa agcgtttagg tttaacatag
     2041 gtgttgatga gcggagtgaa cgcattcata atcagaatgg caaacgacat accctccgga
     2101 tatgcaccga acagacggat gatgacagtc agtaggccga tgcaaacacc ataaatcagc
     2161 atacctttgt ggctcatcgg agaagtcacg tagtccgtag ccataaagac agcacccagc
     2221 atcagaccac cggacaacaa ctgtacgacc ggggatacat aaagttccgg attgaccaga
     2281 tacatgatac cggagaacac gaataccgtc accagaatag ataccggaat gtgccaggtg
     2341 atgattttct tccacaacat gtagaacaaa ccaagcagca gcgccaaggc actcacctca
     2401 ccgagacatc ctccattatt acctatcaga aggtcgaaag ctcccggaag gtcgctcagg
     2461 gacatgcccg gagcaccatt gatgacacct ttcataatag ccagcggcgt agcagccgtc
     2521 gtggcatccg tataggctgt caactggcct acagccggcc atgtcgtcat ctgcacgggg
     2581 aatgaaagca acaggaatac acgtcctgcc agtgcagggt taaagggatt gcaacccaaa
     2641 cctccgaagg acatcttgcc taccccgatg gcaaacaagg caccaaggat gataatccag
     2701 atgggcaggt tggaaggcag gttaaaggcc agcaacacac cggtaatgat ggcagagccg
     2761 tcggtgatgg ttgtggtctc ttttttcatg aggaatttgc cgatggccca ttcaaagaac
     2821 aagcaggctg ctacggaagt ggccgtaaca atcagcgcac ccagtccgaa aaagtaaagc
     2881 gaaacgagga atgccggaat caatgcgata agcacaccgt acatattctt cttcacgctg
     2941 tcaccgccgt gaacgtgggg cgaaagggat acgattaatt tattcatact tcgttatttt
     3001 ttagcttgac gtgcacggat catcgctcct accttaccct tacccaagcg gatataatcc
     3061 agcatcggac ggttggaagg acaagtgaac tggcatgaac cgcattctat acacgacata
     3121 atgtcttctt tctctactct ttcaaaatct ccgtgggccg aaacggtagc cagcagatac
     3181 ggctccaacc ccatcgggca ggctcccacg cacttagcac aacggataca aggctgtact
     3241 tcgccgcgct tggcttcctt ctcgttcata atcagaatac cggagcttcc tttggctgtc
     3301 ggtacatccg tatttaccag agctttaccc atcatcgggc caccgccgat aatcttaccc
     3361 gtatcttcgg gcagaccgcc gcaagcttca atcagctgct tcatcggcgt accgatacgt
     3421 gccaggaaat tggacggctt tgccaacgac ttaccagtca cggtaatgac acgctcaaac
     3481 agaggtttgt tcttctgtac ggcctggtaa acggcaaatg cggtacccac attctgcacc
     3541 acagctcccg tggagatagg caacgcaccg gctgcaacct ggcgactgat gacagcatca
     3601 atcaactgct tttcaccacc ctgcggatat tgtaccttca agggtaccac ctcgatacct
     3661 gcatagctgg aagcaacctt cgtcatcagc tggatggcat cgggcttatt gttctcaatg
     3721 ccgatgaatg ccttgttcac ctttaccgcc ttcatcagaa tggatacacc taccataatt
     3781 tcttccgcat gttccagcat cagctgatgg tcggcagtca gatacggctc gcactctacg
     3841 gcgttgatga tgacacactc tgccttgaat gcaggaggag ggcacaactt gacctgcgta
     3901 ggaaagcatg caccgcccag acctacgata ccggcgtcgg cgattttctt cacgatttcc
     3961 tcggaagtca gactgcattc cttcaccaac gtttcggaac ggtcaatgga ttcttcccat
     4021 tcatcccctt ctacgtcaat gaatatagca ggcttggcgt aaccgctggc atcgacaatc
     4081 gtgtcaatct tagcgacttt cccgctgaca gacgaatgaa tggctgctga tacaaaaccg
     4141 ccgggctcgg caatctttgt acccactttc acaacatcac ctttggcaac gataggcttg
     4201 gcaggagcac cgatgtgctg tcccagcaag atagcggcct tggccggaat ctctgccttg
     4261 atgataggct gatgtgctga aagtttattt tcgtgtggat ggactccacc aattgaaaat
     4321 gtcttcaaca tacaattctg tatttttagt cgtttattta ctttattaat tcatacctca
     4381 acttgggaag tctaaacctc tgctttggga gtctcaacct cagctttagg agctgcaacc
     4441 tttacttggg gagctgcatc gtcagccttc ggtttgcgcg gcgggaagtt gagggcaatg
     4501 attgtgtttt gcggacaagc ttcctcgcac ttgcgacagg atttacactt attggggtca
     4561 atgtaagcca gattgttttc cagcgtgata gcctcgaacg gacaaacctt cacacacttg
     4621 ccgcaaccga tacatgccac ggtacaagcc ttgcgtgcta cggccccctt gtccttgttt
     4681 acacactgta cgtaaatacg acgtgatttc ttgccttgag gacggatttc aataatagat
     4741 ttcggacaag ccttggcaca agctccacaa gccgtacact tttcctcatc cacttcggga
     4801 agtccggtct ccggattcat gtggatagca tcgaactggc aggcagccac acagtcgccg
     4861 catcccagac agccataact acaacccgtt tcaccaccat agagagaagc cgcaatggca
     4921 caactcttgg cgccatcgta ttggttcaca cgaggacggt tggcacaagt tccattacat
     4981 ctcaccaccg caaccatagg ttcggcagca gcggcatcca agcccagaat ctcggcaatc
     5041 tttgtcatga cgggctgtcc acccaccgga caaagtttac catccagcga acctgccttt
     5101 acgcaagcat ctgcaaatcc gctacaaccg gggtaaccac atccaccgca atttgcctgg
     5161 ggaagcacct ctgctacctg ggcaatccgc ggatcttcat acacggcgaa tttcttggaa
     5221 gccacgtaaa gaatagcggc cgataccagc gctataactc ccaatgaaat cactgcaatc
     5281 agaattacat tcataaatta gttgtttatt aattatttgt tttattatta gttagttcat
     5341 cggtcgtacg gagaatgaga acttcttacc catccgcaac ttgttcagcc acaatatata
     5401 ataataaggt acaagaagtg ctagcgaaca aagcgcggaa cgcagctcgt cattccagat
     5461 agccataaag acaaatagtg agattatcag aataaggaaa ggaaatataa aggcaaacag
     5521 aactgccatc actcccattg aaagttcgcc cgtcacccat acacggtcgc cgggctggta
     5581 ggatgcggca ttggcatcgg ccacatcgac aagtttctct ttcgtatccg cagaggtaca
     5641 atgtcccttg acactacacg aagcgcacgc tgaagtctgg atgattctca cttggagatg
     5701 agaaccgttt atgttttcca caataccttg atgttttata gtattcgcca ttttgcaaag
     5761 tgtgcattac aaatcgcggc aaatttacgc attatttgtg aactgcaaac ctttcctatg
     5821 cattttctgt gttcgtaaac gtgttttttc tatgttttta tgttttttca cctgccacag
     5881 actacaaaaa gacaaaaaac agacggtctg tcaaggaaaa acagaccgtc tgactaacca
     5941 aaacagataa tctgttcact ccgaacagac catttgttta tttaccattt ataattgata
     6001 ccgaaactga gcaattcttt tacctgaaaa tagctgtccc cttccgtcgg cttggcactg
     6061 tcgtcatagc gggcgtgcac ataaagcttg gtggaaagat agcggttcag cacaaagttc
     6121 accgtgtttt cccattcgat acgtgtccac tcataactgg tctggaagtc taggcgggaa
     6181 tccagcgtaa tggaaggaat gatggtccac gaaagtgtag gctgtatctg cgaaccgaag
     6241 ttatgcttca cgcacttgcc ctcctcaaga ccgaaactca cttcattcac acccttattc
     6301 cccacatagc gcagcatgta cgtcagcgga gctatgaaaa cggacaagct gaatttctgc
     6361 tttttcagct tgtagtccat accgatactg ctcgaccaat ctgccggagc aaagaaagcg
     6421 gaaaccagct cttcactgtt ggccttgtag ccattgcaga actgggtctt aaactcagtc
     6481 gtgatggtat aataccactt ggatgcagcc tgaataccca gtttactgta cagccggagt
     6541 tggtcggtac ttaccagata gttatgaaac tcgtcggaag gtgccgagct gaagcctagc
     6601 ttggcatcga gcagattttc ccactgcacc ttctcacggt cattatagtt ggcaaacaat
     6661 tgcaggttgg caagcacggc gttagtgctc tcgcctccct tgtaccagtt gtcggagata
     6721 tagttctgtg taatctgcaa cgaaccgttt ccaccggtca cccaccagtt gggcttgtgg
     6781 ataattacgt cggcttcctc cttcactccc accatattct cttgtgcaaa cagtttcacg
     6841 acggacggct tggaagaaac ctccttctct atattatcct tgaatatctt ccctttcatc
     6901 acctccttct cggtcattac aaccagattg ggacaattca catacgtgtt cagcagcgta
     6961 cggtccacca gtttgttggc tcggtccttt gaggtgaaac tcagtgtgtc gaacggcaac
     7021 atctcgcgcg tcagggcagg caccgtatca ggcacctgga aatgccagtc caccttggaa
     7081 aggcgtctca tgggggcata ataataggta aggggaagga acaacctata gtagttcgga
     7141 ttggaaggta tataacgctc cggagtcgtg gggtcattca aataatccag cactccgata
     7201 tacctttcat ataatatgga aacagtatcc agcctgtacc ccataccttc cggtttcaat
     7261 ttcagaatca tgtattcttt cattatatcc ggcaaggtgt cggctttggc agttgtttcc
     7321 tgtccactgt tcttcgaggc ggtatccagc gtattccgtg ccatcaccga cgaagaaatc
     7381 atcgtagcaa ttaaccaaaa tgcaatgtgt ctattcttca taatgcccta aagtctatgt
     7441 ttcgagcgca aatttagctt aaaatgttta gaaaacatag aaaagccata agaaaaaggc
     7501 aagaaggact ttcttcgatg aaatcgtatt ttttaataat tgtttcatcg aaactttctc
     7561 tacttcctct tttttttata attttgcgct ttttaagttc tacgtgtact gacgggagca
     7621 gtgcgcaccc tgaacgacaa gccgtatagg ctcttggcat tagattaaac aattaataaa
     7681 ataatatagt tgtgggagaa acaaagtata ttttcgtcac cggtggtgtt gcctcttcat
     7741 taggtaaagg tatcatctca tcctccatcg gtaaattgct gcaagcaaga ggttacaagg
     7801 taaccatcca gaagtttgac ccgtacatca acatcgaccc gggtacactg aacccttatg
     7861 aacacggcga atgctacgtt accgtggatg gccacgaagc cgacctcgat ttgggccatt
     7921 acgaacgctt cctgggcatc cagaccacca aggccaacaa tatcacgacc ggacgcatct
     7981 acaaaagcgt catcgacaaa gagcgccggg gtgactatct gggaaagacc atccaggtta
     8041 ttccccatat tacagacgaa atcaagcgta atgtaaaact gctgggaaac aaatacaaat
     8101 tcgactttgt tattaccgag attggcggta cagtgggtga catcgagtct ctgccctatc
     8161 tggaaagcat ccgtcagctg aagtgggaac tggggaaaga cgccttgtgc gtacacctta
     8221 cttatgtccc ctacctggct gctgccggtg aactgaagac caagcccacc cagcactccg
     8281 taaaggaact gcaaagtgcc ggtatccaac ctgatgtcct cgtactgcgt acggaacacg
     8341 agttgagtac caccctgcgc aagaaagtgg ctctgttctg caatgtggac gaaaatgccg
     8401 tggtgcagag catcgacgcg cctaccatct acgaggtgcc catcttgatg cagagccagg
     8461 gactggacgt taccattttg aagaaaatgg gacttcccgt cggcgacact ccgggactgg
     8521 gaccgtggcg cgctttcctc gaacgccgtc acaaagccga agagactgcc ccgctgcaca
     8581 tcgcattggt gggcaaatat gacttgcagg atgcctacaa gtccatccgc gaggcccttt
     8641 cacaagcagg aacctacaat gaccgcaagg tatcggtaga cttcgtgaac agtgaaaagc
     8701 tgactgacga gaatgtggca gaagccctga aaggcatggc aggcgtactt atcggtccag
     8761 gcttcggcga acgcggcgtt gccggcaagt tcgtagccat caaatatgcg cgtacgcacg
     8821 acatccccac cttcggtatc tgtctgggta tgcagtgtat cgccatcgaa tttgcccgta
     8881 acgtactggg ttatgccgat gccaactcac gtgagatgga cgaaaagaca ccgcacaatg
     8941 tcatcgacat catggaagag cagaagtcca tcaccaatat gggtggaacc atgcgtctgg
     9001 gtgcctatga atgtgttctg cagaaaggca gcaaggcata cgaggcatac ggtaccgagc
     9061 atatccagga gcgtcaccgt caccgctacg agttcaacaa cagcttcaag gaggcctacg
     9121 aagcagcagg catgaagtgt gtgggtataa accccgaatc ggacctggta gaaattgtcg
     9181 aaatacccgc attgaagtgg tttgtcggta cccagttcca tcccgaatac agcagtacgg
     9241 tattgcatcc gcacccactg ttcgtagcat tcgtgaaggc cgccatcgaa aatgaaaacg
     9301 aaaagaaata atttgtaata agtaatttgt aatcaacaaa gaatggataa aaataccatc
     9361 acaggtcttg ttctgatagc gatattgtta gtaggtttca gctttctgag ccgtcccagc
     9421 caggagcagt tggaagcaca gcaacgttac tacgactcca tagcccaggt gcaacagcgc
     9481 gaagccgact tgaaagccaa ggcggaagca gccctggcca acgaaagcgg agcggaagca
     9541 agcgttgact ccactgccct cttcttcgac gcccgtcaag gaaccaactc gcaggtaacc
     9601 atccagaaca acctggcaga aataactgta gatacaaaag gcgggcgcat agcttcggcc
     9661 acgctgaagg aatacatggg acaagacaag acgacccccg tcacactgtt cagcggcaat
     9721 gacgcttcca tgaatttcct cttttacaac aagaaagaga ctatccagac ggaagactat
     9781 tatttcaccg cagtaaaccg tacggacagt accgtcacca tgcgtttgtc ggcagacagc
     9841 aacagctata tcgactttac atatcgcatg cacaatgaca catacctgat agactttact
     9901 attcaagcag tcaatatgga aggtaagctg gcggctacca acaattatgt ggacatcgag
     9961 tggtctcagc gtgcccgtca gatagagaag ggttacacct acgagaaccg tctggctgaa
    10021 ctgacttaca aaatcaccgg agagggtacc gattatctgt ccgccaacaa gaacgacgaa
    10081 aaggaagttc cggaacgcct ggactggatt gctttcaaga accagttctt ctcttcagta
    10141 tttttggcag atgccgactt tgaaaagacc aaactgagtt ccaagatgga gactcaaggc
    10201 agcggctaca ttaaggacta ttctgcggag atgagcacga agttcgaccc tgccggcaag
    10261 gaacctaccc agctgttctt ctacttcggc cccaatcact acaagaccct gaccgcactc
    10321 gacaaggggc gtgacgagaa gtgggagctg aaccgtctgg tctatctggg ctggccgctc
    10381 atccgctgga taaacaaatg gttcaccatc aacatcttcg actggttgtc cagttggggg
    10441 ttgagcatgg gtatcgtact gttgttcatg acgttaatcg taaaagctgt ggtattcccg
    10501 gctacgtgga agacctacat gtcttctgcc aagatgcgcg tactgaaacc gaaaatcgac
    10561 gagataaaca agaagtaccc caagcaggaa gatgccatga agaagcagca ggaagtgatg
    10621 ggcctctaca gccagtacgg agtcagtccg atgggtggat gtctgccgat gctgatacag
    10681 ttccctatct tgatggcctt gttcatgttc gtgccgagtg ccattgaact ccgccagcag
    10741 agcttcttgt gggcagacga tctttccact tacgatgcgt tcatcaactt cccgttccat
    10801 atcccgttcc tgggaagcca cctcagcttg ttctgcctgc tgatgacggt taccaacata
    10861 ttgaacacga agtacatgat gcagcaacag gatacgggtg ccaatccgca gatggctgcc
    10921 atgaagtgga tgtcatacct gatgcctatc atgttcctct tcatattgaa cgactatcct
    10981 tcgggattga actattacta cttcatctct acgttagtca gtgtggtaac aacgctcatc
    11041 atgcgcaaga caaccaatga ggaagccctt cttgctcagt tggaagccaa caagaaagac
    11101 ccgaagaaga tgaagaaaac cggtttcgcc gctcgtctgg aagccatgca gaaacagcag
    11161 gaacagatga tgaaagaaaa acagaacaaa aagtagtaag actaccgttc aagatattct
    11221 tttgcagaaa gccggacaat gacatttgcc cggctttctt atccttacgc caatgaaaaa
    11281 atcacagact ctaaattatg cagactaaat acacctacaa acaaatctgg cttatagcct
    11341 accccatcct aatcagcctc cttatggagc aactgatagg tatgacggac accgccttcc
    11401 tcggacgtgt gggcgaagtc gagctgggag catctgccat cgccggtgtc ttctacatgg
    11461 tcatcttcat ggttgccttc ggtttcagca tcggggcaca gatactcatt gcccggcgca
    11521 acggcgaaca gcagtataag gaaatcggtg acttgttcta tcagggcatc tatttccaag
    11581 tcgggatggc gacagtcatg ttcctgctgt cctattgctt ctcgccgatt atcctgaaac
    11641 gcatcgtagc ctcggaacat atctacgaag cagccaccag ctacctgcat tggcgtgtat
    11701 tcggtgcctt cttctcgttc agcgcagtca tgttccgtgc ctttttcttg ggaaccaccc
    11761 agaccaagac actgacactg aactccatcg tcatggtgtt gagcaatgtc gtattcaact
    11821 atatcctgat tttcggtaaa ttcggttttc ctgcactcgg cattgccgga gctgccatcg
    11881 gctcctcatt ggccgagctg gtttcgctgt tattcttcat cctctatacc cgtagccgta
    11941 tcgactgctg caagtacggg ctggaccgta ttccgaagtt ccggctggac gtattgaaac
    12001 ggatgctgaa cgtctctttc tggaccatga tacagaattt cttctccctc tccacctggt
    12061 tcttgttctt cctttatgtg gagcatctgg gagagcgctc gctggcagtg accaacattg
    12121 tccgcaacgt gtccggcata ctgttcatgg tactcatggc gtttgcctct acctgcgggt
    12181 cactggtcag caaccttatc ggtgcaggcc actccgattg cgtggcaggc actatccggc
    12241 agcacgtacg catagcctac gttttcgtac ttccgctggc attgcttttc gcgctgttcc
    12301 ccaagctgat tctgggaatt tataccgaca tacccgacct gcaggacgct gccgtgcatt
    12361 cgctttgggt gatgtgctcc acctatctgt tcctggttcc tgccaatgtc tatttccagg
    12421 cagtttccgg aaccggcaat acgcgtactg cattgggcat ggagctggca acgctggtca
    12481 tctacacagc ctatatcacc tacattattc tgattctgca actcgacgtg gccatctgct
    12541 ggacctcgga aatggtttat tccagcttta ttctcatttt ctgctggcta tatatcaaac
    12601 gtgggaattg gcaaggaagg aaaatttagt atctttgcat tgaaataact gaaacaaaaa
    12661 gcatatatga aacaagtaaa tctactactt atgtcagcag ccatgacatt ggcctcttgc
    12721 ggaggcacaa aagatgccgg acagcagcag gacgcagcaa cgctcatcca gcggtcggac
    12781 atcaagattg aaggaaagcg tatgacaccc gaggcactct gggcgatggg acgcatcggc
    12841 agtgtggccg tatcccccga cgaaaagcaa attgcctaca cggtatccta ttacagcgtg
    12901 ccccagaaca agagtaacag cgaagtcttc gtcatgaatg ccgacggtag tgacaatacc
    12961 cagataacgc atgacgcctg gcaagaagga cagcccacgt ggtttaagga cggcaagaag
    13021 cttgccttcc tttgcaacga aagcggcagc agccaggtat gggaaatgaa tcccgacggc
    13081 agcggacgca agcagctgac tcaatacgag ggagacatcg aagggttctc tttctcgccc
    13141 gacggcaaga aactcctttt cattgcccag gtaaagaccg tgaagagtac ggcagacaaa
    13201 catccggacc ttcctaaagc caccggcatc atcgttaccg acctgatgta caagcattgg
    13261 gacgaatggg tgactactgc tccccatccg ttcgttgccg atttcgacgg caatgccatc
    13321 agcaatgtca ctgatattct tgagggagag ccatacgaaa gcccgatgaa gccctggggc
    13381 ggtatcgagc agctggcatg gagcccgtct tctgataagg tggcctatac atgccgtaag
    13441 aaaaccggac tggcgtatgc catttccacc aactccgaca tttatatcta cgaccttgcc
    13501 tccaaggaaa ccaaaaacat cacggaagaa aacaagggat atgatacgaa tccccaatac
    13561 tctcccgacg gcaaatacat cgcctggcag agcatggagc gtgacggcta cgaagccgac
    13621 ttgaaccgct tgtttatcat gaacctcgag accggcgaga aacgttttgt aagcaaagct
    13681 ttcgaatcga acgtggacgc cttcttgtgg aacaaagatt cccggagcat ctacttcatc
    13741 ggtgtatggc atggcgagac acagatttac aacatcgacc ttgtcggaaa cgacaagctt
    13801 acccagctca ccgacggcat gcacgactat gcttcgcttg ccctttgcgg aaacaagatt
    13861 atcgccaaac gccattccat gagcatgggc gacgaaatct atgccgtaaa cagtgcacgc
    13921 aacggcgacg cttttgcaga agcagtgcaa ctgaccacag agaacaagca gatttacgac
    13981 cagctggaga tgggtaaagt ggaagcccgc tggatgaaga ccaccgacgg caagcagatg
    14041 ctgacctggg tgatttatcc tccgcagttc gaccctaaca agaagtaccc caccctcctc
    14101 ttctgtgaag gtggtcctca gagtcccgtc agccagttct ggagctaccg ttggaatttc
    14161 cagattatgg cagcaaacga ttatatcatt gtagctccca accgtcgtgg tcttccgggc
    14221 ttcggtgtag agtggaacga agccatcagc ggtgattatg gcggccagtg catgaaggac
    14281 tacttcactg ccattgacga aatggcccag gaacctttcg ttgacaaaga ccgcctgggt
    14341 tgcgtaggtg ccagcttcgg aggtttttcc gtatattggc ttgccggaca ccatgacaaa
    14401 cgcttcaagg cattcatcgc acacgacggt atcttcaaca tggaaatgca atatctggaa
    14461 acggaagaga aatggtttgc caactgggat atgggcggcg cttattggga aaagaacaac
    14521 gctacggcac aacgcacttt tgccaactcc ccgcatctct tcgtcgacaa atgggacacc
    14581 cctatcctct gcatccacgg agagaaggac ttccgcatcc ttgccaacca ggcaatggcc
    14641 gccttcgatg cagccgtgat gcgtggcgtt cctgccgaac tgcttatcta tccggacgaa
    14701 aaccactggg tgctgaagcc tcaaaacggc gtgctgtggc aacgtacctt ctttgaatgg
    14761 ctggacaaat ggctgaagcc ggctaagtaa agcccctcaa aaacaataaa aacaaataat
    14821 cccggactct ttgtcaagaa tccgggatta tttgttttta tcgtacaccg cccgattcat
    14881 tttttatgac tataatttgg gcagttcaaa taaagtcaat acatttgctt tatgcacact
    14941 ccaaagaagt gtaaacaata tgtcctaata taacccgata aaagatgaat gaaaattggc
    15001 ctgagattgt ggaaacactg ataccgtatt ttgaaacaaa ttcggtagaa ggtgactacc
    15061 agcgggaaat agagaactgc ttgaaatttc ttggatggaa gaagaccaat ggaacaatgg
    15121 tatcccaata tacattaccg ataggcaata gcaactccat acgcccggac attgtacttt
    15181 ggcgaaagaa cgagcatgac acacaatccc ccgtactccc tattgaaata aagcgtccgt
    15241 ctaatatacg aaatgaaaga caagaaaatc aactgatgtc gtatatgcgc cagt
//
