LOCUS       c00150_gnlPro..        14369 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OFPFGEMK_150.
ACCESSION   c00150_gnlPro..
VERSION     c00150_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 22:09:53
            Original ID  :: gnl|Prokka|OFPFGEMK_150
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14369
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14369
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1134:7216]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1135..7216
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..14369
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14369
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(72..644)
                     /locus_tag="ctg150_1"
                     /transl_table=11
                     /translation="METVENKYITVAYKLYSIENGEKDFEEEAPVEHPFQFISGLGMTL
                     EPFEAQIKDLQIGDKFDFTIPASEAYGEYDDDHVIDLPKEIFMIEGEFDSDRVVEGAVI
                     PLMTSEGQRINGSVVEVKEDIVVMDMNHPLAGCDLNFTGEVVESRLATNEELAEVARMM
                     GGGCGSCGCGDCGDGCGDHECGGGCCH"
     CDS             1135..2937
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg150_2"
                     /sec_met_domain="ILVD_EDD (E-value: 5.5e-219, bitscore:
                     717.3, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHQLRSSFSTQGRRMAGARALWTANGMKKEQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQFVKEEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVGDKEVAQIEQHACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRKRLFEDAAKLIVANAFRYYEEGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGADFKMDDIDMLSRKTPCLCKVAPNTQKYHVQDVNRAGGIIAIMDELAKGG
                     LVDTNVRRVDGMTLAEAIDRYSITSSNVCKEAIKKYSSAAAGKFNLVLGSQNASYKELD
                     TDRATGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDA
                     ACDGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARPMTPVTRNRE
                     VSKALKAYASMVSSADKGAVRLID"
     CDS             3029..4780
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg150_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.5e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRQAAELI
                     NGAERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTDHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             4813..5373
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg150_4"
                     /sec_met_domain="ALS_ss_C (E-value: 6.1e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             5370..6122
                     /locus_tag="ctg150_5"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYVAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVMFTEK"
     CDS             6173..7216
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg150_6"
                     /sec_met_domain="IlvN (E-value: 3.8e-47, bitscore: 149.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3.5e-41, bitscore: 130.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACQKGTIIMCLLSDAAVMS
                     VWPTIKPYLTPGKALYFSHGFAITWNDRTGVVPPKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAVYQDATGKAFDKTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVQKLYASVKSGNEAQISIDSNSKPDYREKLNAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(7278..9191)
                     /locus_tag="ctg150_7"
                     /transl_table=11
                     /translation="MITFATMKEQDSNSPIIHLQQQQLLLRMEYEYEKEEFKRQTENMG
                     IARKVKRGLCWYPATPGRSYYNSLNQLVIEITHTENTDIEHNFEFGRPVCFFRQSADGK
                     ITYMNFTATVSYADETRMVAIMPGAGAVMEVQETDNLGVQLYFDETSYRTMFEALEDTL
                     RSKGNRLAELRDILLGTSKAGFRELYPVRFPWLNSTQETAVNKVLCARDVAIVHGPPGT
                     GKTTTLVEAIYETLHREPQVLVCAQSNTAVDWISEKLVDRGVNVLRIGNPTRVNDKMLS
                     FTYERRFENHPLYPELWSIRKNLRELGSRARRGSYDEREGVRSRMSRLRDRATALEIQI
                     NSELFDGAHVIASTLVSSNHRLLNGRRFGTLFIDEAAQALEAACWIAIRKADRVVLAGD
                     HCQLPPTIKCYEAARGGLERTLMEKVVSNKPAVVSLLKVQYRMHEEIMKFPSQWFYNGE
                     LEAASEVRYRGILDWDTPIHWIDTSEMDFKEEFVGETFGRINKAEADLLLSELKIYINR
                     ISGNRILEEKIDFGIISPYKAQVQYLRNKIKADASLKPYRSLFTVNTVDGFQGQERDVI
                     FISLVRANEEGQIGFLNDLRRMNVAITRARMKLVILGEAETLKHHGFYRKLLEFIQNIG
                     NQ"
     CDS             9306..11549
                     /locus_tag="ctg150_8"
                     /transl_table=11
                     /translation="MVYDLTMLKTFYAAYSEKIERVRNVLQRPMTLAEKILYAHLYDGD
                     KVKNYRRGEDYVNFRPDRVAMQDATAQMALLQFMNAGREQVAVPSTVHCDHLIQAYKGA
                     KEDIATATKTNEEVYNFLRDVSSRYGIGFWQLGAGIIHQVVLENYAFPGGMMVGTDSHT
                     PNAGGLGMVAIGVGGADAVDVMTGMEWELKMPRLIGVHLKGKLSGWVAPKDVILKLAGI
                     LTVKGGTNAIIEYFGPGTASLSATGKATICNMGAEVGATTSLFPYDERMGTYLKATGRE
                     EVAKMAASVAADLRADDEVLANPEKYYDRIIEIDLSLLEPYINGPFTPDAATPISKFAE
                     VVITNNYPRRMEVGLIGSCTNSSYQDLSRAASLARQVKEKNLKVASPLIVNPGSEQIRA
                     TAERDGMIAAFEDIGATIMANACGPCIGQWKRHTDDPERKNSIVTSFNRNFAKRADGNP
                     NTFAYVASPEITMALTIAGDLCFDPLRDTLVNAKGEVVKLSEPVGEELPAHGFIGGKEG
                     YIAPGKGQTEITVNPHSQRLQLLTPFPAWDGMDLLNMPLLIKVQGKCTTDHISMAGPWL
                     RFRGHLENISDNMLMGAVNAFNGETNKVWNRSTNTYGTVSGTAKLYKAEGIPSIVVAEE
                     NYGEGSSREHAAMEPRFLNVRVILAKSFARIHETNLKKQGMLALTFTDKADYDKIRERD
                     LISVMGLKDFASGRTLKVVLHHEDGSKESFEVQHTYNEQQIAWFRAGSALNAR"
     CDS             11553..12713
                     /locus_tag="ctg150_9"
                     /transl_table=11
                     /translation="MEKITVPFISGDGVGAEVTPSMQAVVNAAVRKSYGDRRGIEWKEV
                     LAGERAFHETGSWLPDETMEAFRTYKVGIKGPLTTPVGGGIRSLNVALRQTLDLYVCQR
                     PVRWYKGIVSPLKEPQKVDMCVFRENTEDIYAGIEWEAGTPEAEKFYRFLHDDMGVTKV
                     RFPETSSFGVKPVSREGTERLVRAACQYALEHHLPSVTLVHKGNIMKFTEGGFKKWGYE
                     LAECEFGKELAEGCLVIKDCIADAFLQNTLLIPEEYSVIATLNLNGDYVSDQLAAMVGG
                     IGIAPGANINYKTGHAIFEATHGTAPNIAGKDIVNPCSIILSAVMMLEYLGWKEAASLI
                     ENALEESFTEARATADLARFMPGGVSLSTSTFTREIVRRIENGNNE"
     CDS             12726..14069
                     /locus_tag="ctg150_10"
                     /transl_table=11
                     /translation="MKKEYLIYKLSEDLKEATRIENELFRKFDVKRGLRNEDGTGVLVG
                     LTQIGNVVGYERIPGGGLKPIPGKLFYRGYDVDDLAHAIIKEKRFGFEEIAYLLLSGRL
                     PDKEELSSFRELINDNMPLEQKTKMNIIELEGNNIMNILARSVLEMYRFDPDADDTSRD
                     NLMRQSIELISKFPTIIAYAYNMLRHATHGRSLHIRHPQENLSIAENFLYMLKKDYTEL
                     DARTLDLLLVLQAEHGGGNNSTFTVRVTSSTGTDTYSSIAAGIGSLKGPLHGGANIQVA
                     DMFHHLQENIQDWTNVDEIDTYFTRMLNKEAYNKTGLIYGIGHAVYTISDPRAILLKEL
                     ARDLAREKGKEREFAFLELLEERAIDVFGRVKNNGKTVSSNVDFYSGFVYEMIGLPQEI
                     FTPLFAMARIVGWCAHRNEELNFEGKRIIRPAYKNVLDEVAYVPIKKR"
ORIGIN
        1 gaattatcat gcagcatact tatattgcgt agtttgattc tttcattttt aattcttcat
       61 ttttaattct tctagtggca gcatccgcct ccacattcat ggtcgccgca tccgtcgcca
      121 cagtcaccac aaccgcagct gccgcaaccg ccacccatca tacgggcgac ttcggcaagt
      181 tcttcgtttg tagccaggcg gctttccact acttctccag tgaagttcaa gtcacaacct
      241 gcgagcggat ggttcatatc cattacgacg atatcttcct tcacttctac cacacttccg
      301 ttgatgcgtt gaccttcaga agtcatcaag gggataacgg caccttctac tacacgatcg
      361 ctgtcgaatt ctccttctat catgaagatt tctttgggga ggtcaataac atggtcgtcg
      421 tcatattcac cataagcttc tgatgccgga atggtaaagt cgaatttatc gcctatttgc
      481 aagtctttta tctgggcttc aaagggttcg agtgtcattc ccagacctga gataaactga
      541 aaaggatgct ctacgggtgc ttcttcttcg aaatcttttt ctccgttttc gattgagtac
      601 agcttatatg ctacggtgat gtacttgttt tctactgttt ccattaattt tctatcttta
      661 tttaattagt aaatactgtt tttttgagta tttgaagaga caaagatacg aattatttgt
      721 ttcgggatgt agagagcctt tggtaatttt cagattatta aatggtttca atgattggca
      781 atacatttac attggctgtc tgaatggttc tatttagaac tgttaagtga taaaatagga
      841 ttttagggcg atattttctt acgattattc atatttatct tatttttttc ttcaatttgt
      901 ttggagatta taaaaaagcc cttacctttg cagcacgttt gaaacaaaaa agaagaatta
      961 agttatgaat ttacatacat ctattaacct ggcagtcctg catattattc gcgtcgtggt
     1021 ggtggcatca agagcgtgag aaaggttatg tatgtattcg tacgttagaa gataatttat
     1081 taagcctttc tcactatagt gggagaggct ttttcattaa aaggagattt gaaaatgaag
     1141 catcagttac gcagctcgtt cagcacacaa ggtcgccgca tggcgggagc ccgtgcattg
     1201 tggacggcga atggtatgaa gaaggaacag atgggtaagc ccattatcgc tatagtcaat
     1261 tcatttacac aattcgtccc cgggcatgta cacctgcacg aaataggcca gtttgtaaag
     1321 gaagagattg aaaagctggg gtgttttgct gcggagttca atacgattgc cattgacgac
     1381 ggtatcgcta tgggacacga cggtatgctt tattccctgc cttcaagaga tatcattgcc
     1441 gatagtgtgg agtatatggt aaatgcccat aaggcggatg ctatggtttg catcagtaac
     1501 tgtgacaaga ttactccggg gatgttgatg gcggctatga ggctgaatat accgactgtg
     1561 tttgtttcag gcggtccgat ggaagccggg gaatggaacg gacagcattt ggatttgatt
     1621 gatgccatga ttaaatctgc tgatgaaagt gtgggcgata aagaggtggc acagattgag
     1681 caacatgcct gccccacttg cggatgctgc tcaggcatgt ttaccgctaa ttccatgaat
     1741 tgcctgaatg aagcgattgg attggcactg cccggtaacg gcacgattgt agccactcac
     1801 gaaaatcgca agagactgtt tgaggatgca gctaagttga ttgtagcgaa tgcctttaga
     1861 tattatgaag aaggggatga gagtgtactc ccgcgcagta ttgctactcg cgaggcattt
     1921 ttgaatgcca tgacgctgga tattgcgatg ggcggttcca ctaatacagt acttcatttg
     1981 ttggctgtgg ctcacgaagc cggagcggat tttaagatgg acgacattga catgctctct
     2041 cgcaagaccc cctgcttatg caaggtagct cccaataccc aaaagtatca tgtacaagac
     2101 gttaaccgtg ccggtggcat cattgccatc atggatgagc ttgccaaggg cggattggtc
     2161 gatacgaatg tccgccgtgt ggatggaatg acgttggcag aggcaatcga ccggtatagt
     2221 attaccagct ctaatgtatg taaagaggca atcaagaaat actccagtgc ggcagccgga
     2281 aagttcaatc tggtactcgg ctcacaaaat gcgtcttata aggaactcga tacggaccgt
     2341 gcgaccggtt gtatccgtga tttggaacat gcatacagca aggatggcgg tctggcggtt
     2401 ttgaagggaa atatagctca ggacggttgc gttgtcaaga ctgccggtgt agacgagagt
     2461 atctggaaat ttacggggcc agcgaaagtc ttcgactcac aagatgcggc ttgtgacggt
     2521 attctgggtg gaaaggtggt cagtggagac gtcgtcgtca tcactcacga agggccgaaa
     2581 ggtggaccgg gtatgcaaga gatgctttat cctacttctt atatcaaatc ccgccatctg
     2641 ggtaaggagt gtgcattgat taccgacggg cgtttcagtg gtggtacttc cggactaagt
     2701 atcggacatg tttctcccga agcggctgcc ggtggtaata tcggcaagat taaggatggg
     2761 gacattatcg aaattgatat accgaaccgt tctatcaatg tgaagttgac ggatgaagag
     2821 cttgcagcac gccctatgac tccggtaacc cgcaaccgtg aagtctccaa agcattgaaa
     2881 gcatatgcca gtatggtgag ttccgctgac aaaggggctg tgaggctgat tgattaaaag
     2941 cccccctttc cgaaagcgag gggaggagag aatgaaacaa atttttcaag ctactattga
     3001 gcttttaaat ataatgaata gataaagtat ggctgataat aataaaaaga gtaacttttc
     3061 ctccctctcc caaggagagg gtcggggtga ggctctaata acaggcgcag aagcattgat
     3121 gcgctctctg gagcatcagg gagtaaagac tattttcggt tatccgggag ggagcatcat
     3181 gccggtattc gatgccttat acgaccaccg gaaggaattg aaccacatct tggttcgcca
     3241 tgaacaagga gcaacccatg cggcacaagg ctttgcacgt gtatcaggcg aggttggcgt
     3301 ttgtctggtt accagtggac cgggtgctac caatactatc acgggcattg cagatgccat
     3361 gattgacagt acgcctatcg ttgtcattgc cggccaggta gggacgaact tcttgggtac
     3421 ggatgcattt caagaagtgg acttggtagg cattactcag cctatcacga aatggagtta
     3481 ccagattcgt cgtgcagaag atgtggcctg ggcagtggca cgtgctttct atgtggcaaa
     3541 gagcggacgt ccgggaccgg tcgtgctgga ttttgctaaa aacgcccaag tggagaaaac
     3601 agaatatgcg cctactaagg tggactatgt ccgtagctat cttccagttc ccgaaatgga
     3661 gccggaggcc atacggcagg ctgctgaatt aataaatggt gcggaacggc ctttggtgct
     3721 ggtaggacaa ggcgtggagc tgggagaagc ccagcaagag cttcgtgctt tcattgagaa
     3781 agccggaatg cctgccggat gcactttatt gggactttcc gcattgccta cggaccatcc
     3841 gttgaacaaa ggaatgcttg gtatgcacgg taacctgggg cccaatatca ataccaataa
     3901 atgtgatgtc cttatcgccg taggcatgcg ctttgatgac cgtgtgacgg gtaaattgga
     3961 aacatatgcc aagcaggcga agattatcca ctttgatatt gaccctgccg aaatagataa
     4021 gaatgtaaag actgatgttg ctgtcctggg agattgcaaa gagacactgg ctgccgttac
     4081 ccaattgctg gaacccgcca accatcagga atggattgac agtttccggc aatacgagga
     4141 agtggaagag gaaaaggtaa tccgtccgga attacatccg gcaggaaaag cgctaagcat
     4201 gggtgaggtg gtgcgtgctg tgagtgaggc tacccataac gaggcgatat tggtgactga
     4261 tgtcggccag aatcagatga tgtccgcccg ttatttcaaa tacagcaagg aacgtagcat
     4321 tgttacttcc ggtggcctgg gtactatggg cttcggcctt ccggcagcta tcggtgccac
     4381 ttttggacgt ccggaccgca cggtatgcgt attcatggga gacggcggct tgcagatgaa
     4441 cctgcaggaa ctgggtacca tcatggaaca aaaggctccg gtgaagatga ttctgttgaa
     4501 caataacttc ctgggcaatg ttcgtcaatg gcaggcgatg ttcttcaatc gtcgttattc
     4561 gtttactccg atgatgaatc cggattatat gaagattgct tcggcatatg atattcctgc
     4621 acgcagggta atgacccgcg aggagctggc aaaagcgatt gacgagatga tagcgactga
     4681 cggaccattc ctgctcgaag cttgtgtgga ggaagaagga aatgtaatgc cgatgacacc
     4741 tccgggcggt tcggtcaatc agatgttgtt ggaatgctga agtcatgcga aattaaagaa
     4801 tttactctat ctatggataa aaaactatat acaatcattg ttcattcgga aaactttgcc
     4861 ggtttgctga atcaggtgac ggctgtgttt acccgccggc agataaacat cgagagcttg
     4921 aatgtatcgg cctcctccat caagggggta cataaatata ccattaccgc ttggacggat
     4981 aaggatacca ttgaaaaggt gaccaagcag attaccaaga aaatagatgt gctgcaagcc
     5041 cattatttca cggatgatga aatctatcag cacgagattg ccctttataa aataacgacc
     5101 cctacgctgg aagaaaaacc ggaggtgtcc aaagtaatcc gtaagtacaa tgcccgtatt
     5161 gtggaggtga atgctgtatt tgccattgtt gagaagaatg gcatgagtga ggaaataacc
     5221 aatctttatg aggagttgcg ccagttggat tgcgtacttc agttcgtccg ttcgggtcgc
     5281 gtagccatta cgaccagctg ctttgagcgt gtcaatgaat atctggcgga ccgtgaagca
     5341 aaatatcgtc aaagtaaaca ccaggaatca tgatgagcga gaacaataaa ataggtacct
     5401 acaagtttgt tgccgaaccg tttcatgtcg actttaccgg acggctgaca atgggagtat
     5461 tgggcaacca tttgttgaat tgtgcgggtt tccatgccag cgaccgcggt tttggcatcg
     5521 cgactctaaa cgaggacaat tatacttggg tattgtcccg tctggctgtc gaactggatg
     5581 aaatgcctta tcagtacgaa gatttctcca ttcagacttg ggtggagaat gtctatcgcc
     5641 tttttacaga ccgtaatttc gctatcatcg ataaggaggg caagaagatt gggtatgcac
     5701 gttccgtttg ggcgatgatt agcatgaata cccgtaagcc ggcagatttg ctggctcttc
     5761 atagtggcag cattgtagat tatgtttgcg atgagccttg cccgatagaa aaaccttcgc
     5821 ggataaaggt ggcctcaaag gaaccggttg ctgctttggt agccaaatac agtgatattg
     5881 acattaacgg gcatgtgaac agcatccgtt acattgagca tatccttgat ttgttcccga
     5941 tagagatgta taaggagaag cgcatccgtc gttttgaaat ggcatatgta gccgaaagct
     6001 attatgggga tgagttgact ttgttcatgg atgatgccgg tgagggcgtt tacgatgtgg
     6061 aggtgaaaaa gaatggcagc gaagtggtct gtcgctctaa agtgatgttt acagagaaat
     6121 aaataaattt atcaacgttg gcgtaagcca caaataaaaa ttaaaacaaa aaatggcaca
     6181 attgaatttt ggcggtgtta ttgagaatgt aatgacccgc gaagaatttc ctttggaaaa
     6241 agcacgtgag attttgaaag atgaaacaat tgcagtaatc ggttatggcg tacaaggccc
     6301 gggccaggct tgcaacttgc gtgataacgg tttcaatgtg attgtaggac aacgtccggg
     6361 caagacatac gaaaaggctg tggctgacgg atgggtaccg ggtgagactt tgttcggcat
     6421 cgaagaggct tgtcagaaag gtactatcat catgtgtctg ttgtctgacg cagctgtaat
     6481 gtctgtatgg ccgactatca aaccttattt gactcccgga aaggctcttt acttctctca
     6541 tggttttgct attacctgga acgaccgtac cggcgtggtt cctcctaaag atattgatgt
     6601 tattatggtt gctcccaaag gttccggtac ttcacttcgt accatgttcc tcgagggtcg
     6661 tggcttgaac tcatcatatg ccgtctatca ggatgctacg ggtaaggctt ttgacaagac
     6721 gattgcactg ggtatcggca tcggttcggg atatttgttc gagacaactt tcatccgtga
     6781 agccacttcc gacttgaccg gtgaacgtgg ttccttgatg ggtgctatcc agggattact
     6841 gttggctcag tatgaggtat tgcgcgaaaa cggccatact ccttctgaag cattcaatga
     6901 aacagtggaa gagttgactc aatctttgat gccattgttt gccaagaatg gtatggactg
     6961 gatgtatgcc aactgttcta ctacggcaca gcgtggtgcg ctggattgga tgaccccgtt
     7021 ccatgatgcc atcaagccgg ttgtacagaa attgtatgca agtgtgaagt cgggtaacga
     7081 agctcagatt tctatcgaca gtaactccaa acccgattat cgtgagaagc tgaatgcaga
     7141 attgaaagcc ttgcgtgaaa gcgaaatgtg gcagacagct gttacagttc gtaaacttcg
     7201 tccggaaaac aattaatcag ctttatataa ataggtgaaa taccctcttc ggtgttaccg
     7261 gagggggtat ttctttatta ttgattccct atattttgaa taaactccaa tagcttccgg
     7321 taaaaaccgt gatgtttcag cgtctctgcc tctcccaata tcaccagctt catacgtgcc
     7381 cgggtgatgg ctacattcat tctccttaaa tcattcagga atcctatctg cccttcttcg
     7441 ttggcacgga caaggctgat gaagataaca tcgcgctctt gcccttggaa gccatccacc
     7501 gtatttacag tgaacaagct gcgataaggc ttgagtgaag cgtctgcctt tatcttgttg
     7561 cggagatatt gcacttgtgc cttgtaaggg gagatgatgc cgaagtctat tttttcttcc
     7621 agaatgcggt tgccactgat acggttgatg tagattttca gttctgatag gagcaggtcc
     7681 gcttccgcct tattaatgcg cccgaaagtc tctcccacaa attcttcttt gaaatccatt
     7741 tcggaggtgt caatccagtg gatgggggta tcccagtcca ggatgccccg gtaacgcact
     7801 tcggaagcgg cttccaactc gccattataa aaccattggg aaggaaattt catgatttcc
     7861 tcgtgcatgc ggtattgtac tttcagcaaa gagacaacgg caggtttgtt ggacaccact
     7921 ttctccatca atgttcgttc cagacctcca cgggcggctt cgtagcattt tatggtgggc
     7981 ggaagttggc agtggtcacc cgccaatacc acgcggtctg cttttcggat agctatccag
     8041 caggcagcct ctaaggcctg ggctgcttca tcaatgaaaa gggtgccgaa acggcgtccg
     8101 ttcagtagcc ggtgattgct gcttaccagc gtggaggcta tgacatgtgc cccatcaaaa
     8161 agctctgaat tgatttgtat ttccaatgcg gtggcgcggt cgcgcaggcg gctcatacgg
     8221 ctgcgtactc cttcgcgttc gtcatagctg ccacggcggg cacggctgcc cagttcacgg
     8281 agatttttcc ggatgctcca cagttccgga taaagcggat ggttctcgaa acgacgctcg
     8341 taggtaaagg aaagcatctt gtcgttgaca cgggtcggat tgccgatacg caggacattg
     8401 acgccacggt ccacaagttt ttccgaaatc cagtcgacgg cagtattgct ttgggcacat
     8461 accagtacct gcggttcccg atgcagggtt tcatagatgg cttccactaa ggtggtcgtt
     8521 tttccggttc ccggaggacc atgtacaatg gccacgtcgc gggcacacag cactttgttt
     8581 acagctgtct cctgcgtgga gttcagccag ggaaaccgta cggggtagag ctctcggaaa
     8641 ccggctttcg aggttcccag caatatgtcc cgcaattcgg ccaggcggtt gcctttggag
     8701 cgtaacgtat cttccaaggc ttcgaacatg gtccgatagg atgtttcgtc gaaataaagt
     8761 tgcacgccga ggttgtccgt ttcctgcact tccataacgg caccggctcc gggcattatc
     8821 gctaccatcc gtgtctcgtc ggcatagctt acggtagcgg tgaagttcat ataggttatt
     8881 tttccatcgg cagactggcg gaaaaaacat acgggacggc cgaactcaaa attatgttct
     8941 atatcggtat tttctgtgtg tgtaatttct attactaatt gattcagtga attatagtaa
     9001 cttcgtcccg gagtggcagg ataccagcaa agtccccgtt tcactttccg ggcaatcccc
     9061 atgttttcgg tttggcgttt gaattcctct ttttcgtatt cgtattccat gcgcagcaaa
     9121 agttgttgct gctggaggtg aataatagga ctatttgaat cttgttcctt catggttgca
     9181 aaggtaatca ttcttcactt ccgacggaaa aaatgcttta ttttgttaaa ctattcagcc
     9241 tttttatttg tttatgatat taatttgtaa tctttacaat aatgaaaaac taaaaaatag
     9301 tggttatggt atatgattta acgatgctca aaacgtttta tgccgcttat tcggagaaga
     9361 tagaacgcgt acggaatgta ctacagcgtc cgatgacttt agcggagaaa attttgtatg
     9421 ctcatttgta tgatggggat aaagtgaaga actacagacg gggagaagac tatgtgaatt
     9481 tccgtcccga ccgtgtggcc atgcaggatg caacggccca aatggcctta ttgcaattta
     9541 tgaatgcagg ccgtgagcag gttgccgtgc cttccactgt gcactgtgac catttgattc
     9601 aagcatataa aggtgcaaaa gaagatatcg cgactgctac gaagaccaac gaggaggtct
     9661 ataattttct ccgtgatgtt tcttcccgct atggcatagg tttttggcag ctgggagcag
     9721 gcattattca ccaggtggta ttggagaact acgcatttcc gggtggaatg atggtaggca
     9781 cggactctca tacgcccaat gccggaggtt tgggcatggt ggccattggt gtgggtggtg
     9841 ccgatgcggt ggatgtgatg actggcatgg aatgggaatt gaaaatgccg cgtctgatag
     9901 gcgtacactt gaagggtaaa ttgagtggct gggtagctcc caaagatgtt attctgaagt
     9961 tggcgggtat tcttactgta aaagggggaa ccaatgccat cattgaatat tttggaccgg
    10021 gaaccgcttc attgtctgcc actggaaagg ctaccatctg caatatgggg gcagaggtgg
    10081 gggcgactac ctcccttttc ccttacgatg agcgcatggg tacttatttg aaggctaccg
    10141 gacgtgaaga agtggcaaaa atggctgctt ccgtagctgc cgaccttcgc gccgacgacg
    10201 aagtgctggc aaatccggaa aaatattacg accgcatcat tgaaatagac ctctcgctgt
    10261 tggaaccgta tatcaatggg ccctttacgc cggatgcagc aacaccgata tcgaaatttg
    10321 ccgaggtagt gataaccaat aactatcccc gccggatgga agtcggcctg atagggtcgt
    10381 gtaccaattc gtcctatcag gatttgagcc gcgcagcctc ccttgcccgg caggtaaagg
    10441 aaaagaattt gaaggttgct tctccgctga ttgtcaaccc cggttcggag cagatacgtg
    10501 ccactgctga acgcgacggc atgattgccg ctttcgaaga tattggcgca acgataatgg
    10561 cgaatgcctg cggaccttgt attggccagt ggaagcgcca tactgatgac cctgaacgaa
    10621 aaaattccat cgtcacctct tttaaccgta attttgccaa acgtgccgat ggaaatccca
    10681 acacttttgc ttacgtcgct tccccggaga taacgatggc gctgaccatt gccggtgacc
    10741 tttgtttcga cccgttgagg gatacgctgg tcaatgccaa aggagaggtt gtgaaactgt
    10801 ccgaaccggt cggtgaagaa ctgccggcac acgggtttat aggaggaaag gaaggataca
    10861 ttgctccagg caaaggacag acggaaatta cggtcaatcc tcattcacag cgcttgcaac
    10921 tgctgactcc cttccctgcc tgggatggca tggacttgct gaatatgccc ttattgatta
    10981 aagtgcaagg gaaatgtacc accgaccaca tctctatggc ggggccatgg ctccgtttcc
    11041 ggggacattt ggagaatatt tcggacaata tgctgatggg ggctgtcaat gctttcaatg
    11101 gagagacgaa caaggtttgg aaccgctcca ccaataccta tggaacagtg tcaggcactg
    11161 cgaagctgta taaggccgaa ggtatccctt ccattgtcgt tgccgaagag aattatggtg
    11221 aagggtccag ccgtgagcat gctgccatgg aaccacgctt cttgaatgta cgcgtcattt
    11281 tggcgaaaag ctttgcccgt atccatgaga cgaatttaaa gaaacaaggc atgttggcac
    11341 tgacctttac ggataaggcc gattatgaca agattcggga acgcgacctg atttctgtca
    11401 tggggttgaa agattttgct tcgggacgta cgttgaaggt ggttcttcat cacgaggacg
    11461 ggagtaaaga aagttttgaa gtacaacata cgtataacga acagcagata gcctggttcc
    11521 gggccggttc tgcacttaat gcaagataga atatggaaaa aattactgta ccttttattt
    11581 ccggcgatgg agtgggagca gaagtgaccc catccatgca ggctgtcgtg aatgccgctg
    11641 tcaggaaatc ctatggtgac cggcgtggca ttgaatggaa agaagtgctg gcaggagaac
    11701 gtgctttcca cgaaaccggc tcctggctgc cggatgaaac gatggaagcc ttccgcactt
    11761 ataaggtggg catcaaaggt cctttgacaa cacctgtcgg cggaggtatc cgttcgttga
    11821 acgtggcatt gcgtcagacg cttgatttgt atgtctgcca acgtccggta cgttggtata
    11881 agggtattgt ttctccactc aaagagccgc agaaggtgga tatgtgcgta ttccgtgaga
    11941 ataccgagga tatttatgca ggcatcgaat gggaagccgg aactccggag gctgaaaagt
    12001 tctatcgttt tctccatgat gacatggggg tgacaaaagt ccgttttccc gaaacctcct
    12061 cgtttggcgt gaagcccgtt tcaagagaag gaacagagcg cttggtgcgt gccgcctgcc
    12121 aatacgcgct tgagcatcat ctgccttccg tgaccttggt acacaaagga aacatcatga
    12181 aatttacgga aggcggtttc aagaagtggg ggtacgagct ggcagaatgt gagtttggta
    12241 aagagctggc agaagggtgt ctggtcatca aggactgcat tgccgatgca ttcttgcaga
    12301 acacgttgct tatccccgaa gaatattccg tgattgccac gttgaatctg aacggtgatt
    12361 atgtgtccga ccaactggct gccatggtag gcggcatcgg cattgcaccg ggtgcgaata
    12421 tcaactataa aacggggcat gccatttttg aggctactca cgggacggct ccgaacattg
    12481 ccgggaaaga cattgtgaat ccctgttcca tcatcctttc cgctgtgatg atgcttgaat
    12541 atctgggttg gaaggaagca gcctctctta tagagaacgc cttggaggaa agtttcacag
    12601 aagcccgtgc tactgccgac ttggcccgtt ttatgccggg tggcgtctcg ctgtccactt
    12661 cgactttcac ccgggagatt gtaaggagaa tagaaaatgg gaataacgaa taaaacgaaa
    12721 cgattatgaa gaaggagtat ctgatttaca agctttccga agatttgaag gaagctaccc
    12781 ggattgagaa tgaactgttc aggaagtttg atgtgaagcg cggtttgcgt aatgaggacg
    12841 gcacgggagt cttggtgggg ttgacccaaa taggcaatgt ggtcggctat gaacgcatcc
    12901 ccggtggagg gctgaagcct attcccggca aattgttcta ccgcggttat gatgtggatg
    12961 acttggcaca cgccatcatc aaagagaagc gtttcggttt tgaggaaatt gcctacttgt
    13021 tgctttccgg tcgcctgccc gacaaggaag aactctcttc tttccgtgaa ctcatcaacg
    13081 acaacatgcc gctggagcag aagaccaaga tgaatatcat tgaactcgaa ggaaacaaca
    13141 ttatgaacat cctggcgcgc agcgtgctcg agatgtatcg ttttgaccct gatgcagatg
    13201 acacttcccg cgataatctg atgcggcaga gcattgagct tatttcgaaa ttcccgacca
    13261 tcattgcgta tgcctataac atgcttcgcc atgccaccca tggccgttca ctgcatatcc
    13321 gccatccgca ggaaaacctt tccattgccg agaatttcct ctatatgctg aagaaggact
    13381 acacggagct ggatgcccgc acgctcgacc tgctgctggt tcttcaggcc gagcacggtg
    13441 gtggtaacaa ctccactttt accgtacgtg tcacttcttc taccgggacg gatacttact
    13501 cttcgatagc ggcaggtatc ggttccttga aagggccgct tcatggaggt gccaatatcc
    13561 aggttgccga tatgttccac catctgcagg aaaacattca ggactggacg aatgtggatg
    13621 agattgatac ttacttcacc cgcatgctca acaaggaagc ctataacaag accggcttga
    13681 tatatggtat cggacatgcc gtctatacca tttccgaccc gcgcgccatt ctgctgaaag
    13741 agcttgcccg cgaccttgcc cgcgaaaaag ggaaagaacg cgagttcgct ttccttgaac
    13801 tgctcgagga gcgcgccatt gatgtgtttg gccgtgtgaa gaataatggc aagacggttt
    13861 cgagtaatgt ggatttctat tcgggctttg tctacgagat gattgggctg ccgcaggaaa
    13921 tcttcacgcc tttgtttgcc atggcacgta ttgtcggttg gtgtgcacat cgcaatgaag
    13981 aattgaattt cgaaggcaag cgtattatcc gtcctgccta taagaatgtt ttggatgagg
    14041 tggcttatgt gcccattaag aaacggtaag gattagactt gtatctttta aatcgttcca
    14101 tcacggggaa aaaatcgttc caccatggtg gaacggtttt ttctccatgg tggaatgaaa
    14161 tttactccat gatggaacga ttagattttc gtatctctac tgcttaatct tctcagtaaa
    14221 aaacactggt ttttgcatga aaaaacaatt atccggggaa aacgatttgt ttgttgtgag
    14281 ttttctttat ctttgcttcg cataaataaa gaaccctaat ttccgcaagc gaatgaaatc
    14341 agagattgcc atgcattttt tagtgagtt
//
