LOCUS       gnlProkkaGFCKKEKN_20   12249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GFCKKEKN_20.
ACCESSION   gnlProkkaGFCKKEKN_20
VERSION     gnlProkkaGFCKKEKN_20
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 03:20:05
            Original ID  :: gnl|Prokka|GFCKKEKN_20
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12249
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..204
                     /locus_tag="ctg20_1"
                     /transl_table=11
                     /translation="MHGTAYDIAGKGIASEDSFRQAIYVAIDVFRNRQREKEAHANPLR
                     KQYYEKRDDSDKLKLDSVEEDL"
     protocluster    1..12249
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4703:5057]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4704..5057
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12249
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12249
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             206..1456
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 379.9; E-value:
                     3.1e-115)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg20_2"
                     /transl_table=11
                     /translation="MTKAEIQQVKLRFGIIGNNEALMRAIDIAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EANGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVEKTDVRIVAATNVNLTQAI
                     ADGRFREDLYYRLNTVPIQVPPLRERGEDVVLLFRKFASDFAEKYRMPAIQLTEDGKQV
                     LLGYSWPGNVRQLKNITEQISIIETNREINASILKGYLPEQNNMQRLPALFGVKEDKSF
                     GSEREILYQVLFDMRQDVTDLKKLVHEIMAERGTVANPAVATSAYYTPATPAVVPPVTS
                     SVPTIIHPSVKPVTPVDDDFQDTEEYVEESLSLDEVEKEMIRKALEKHHGKRKSAAQDL
                     NISERTLYRKIKEYGLD"
     CDS             1443..1967
                     /locus_tag="ctg20_3"
                     /transl_table=11
                     /translation="MDWIKKAAFASLLVSLLFLVNSCSMKLGLAPISSIDYTKVKTISI
                     ADFQNRAEYVYAPLATEFNQKMKDMFIQQTRLQLVNSGGDLEIDGEITGYNQYNESVDA
                     SGYSSKVKVTLTVNVRYTNNTNHEEDFEQQFSAFQTYDSSKLLTEVQDQLITLMVKDIA
                     EQIFNATVANW"
     CDS             1972..2745
                     /locus_tag="ctg20_4"
                     /transl_table=11
                     /translation="MTPTHLQQWIQHPETLNRDTLYELRTLVARYPYFQSLRLLYLKNL
                     YLLHDINFGAELRKAVLYVADRRVLFYFIEGDRYTLKSRKVSSLFSGDLEKEPSVDRTL
                     SLIDAFLATVPEEHSQHTELDYAVDYTAYLMQEEPGVDAEDESEVPKLRGHELIDDFIQ
                     KSESSDASDTRREFLVEKEEETEEEEEPSVSPVTEELDDSCFTETLAKIYIKQHRYDKA
                     LEIIKKLSLNYPKKNAYFADQIRFLEKLIINAKSK"
     CDS             2750..3139
                     /locus_tag="ctg20_5"
                     /transl_table=11
                     /translation="MYLLLVILMLIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRK
                     TTDFLEKATWTLAAVMVVFSIVSAYTIPSSTGKGGDVILEQAQQEEKTNPYNMPVGTEA
                     PQSEAPAATTPAETPAPAAEAPAAE"
     CDS             3293..4684
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 101.4; E-value: 7.2e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg20_6"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMAAYYVNDVVAPLKTMLE
                     TDLAWSSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTGLAGADATLFGINEIFGYKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPLARAFGISTPVLLGLVLLLGGMIAFFVFAVMDKKL
                     DKQMEAAAIAAGTEDEEEKFSFKDVKNILVNPGFWLIALLCVLFYSCVFPFQKFASELM
                     IIKYGINENVAGTFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PDINYWLVAIVLMIILGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGWVLDAYCISGKKPDGTNMYDYTVPMCIFTGIACLSLIVALLLKKADKKYGYKLEE
                     PNIQK"
     CDS             4704..5057
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_7"
                     /sec_met_domain="PqqD_RRE (E-value: 1e-10, bitscore: 30.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.8e-17, bitscore: 53.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMEIPEGKVSLLDAVPVRCGHITTEWEGECAVLAYPRFKYEWMRR
                     FLLPKGMSPDIHVRLEEHGTAVWNLIDGHRTVREIISLLARHFGEEENYIPRVTAYVMQ
                     LRKDGFIQLTIRN"
     CDS             complement(5065..6114)
                     /locus_tag="ctg20_8"
                     /transl_table=11
                     /translation="MKKNILMLSALFLSITAMAQTDVTTGVMRGKDYGVTYMLPKTEIE
                     IVLQATKHTYTPGEFCRYADRYLRLNNVSAEPEEFWTLDKIETRIAGVPDKDNVYFVKM
                     KDKTVAPLMELTEDGIVRSINIPFSGKPAAKTPEAKATESSIDPRSFLTEEILMSNSSA
                     KMAELVAKEIYSIRESKNALLRGEADNMPKDGAQLKLMLDNLNQQETAMTEMFSGKIKK
                     EPKTFTIRLTPKEMKDEVAFRFSRKLGVVANNDLAGEPYYISVTDLKSPDVSATEEGKK
                     KVDGVAYNLPGKAQVTLMYNNKKLFDDQLPITQFGTVEYLAPVLFNKNSTIKVLFDTAT
                     GGLIKVDRE"
     CDS             complement(6185..7312)
                     /locus_tag="ctg20_9"
                     /transl_table=11
                     /translation="MKTLLFCMLGLGLTACGSSPRGTNGDQDELAMLIGTYTNGSSKGI
                     YTFRFNQETGTAVPLSSAALPNPSYLVPSEDGEFVYAVSEMNDSTAALSSLAFDRETGE
                     LRLLNTVPTFGADPCYVATNGREVLTANYSGGTMSVFPLQKDGTLAPADTLFQGSATGP
                     DAIRQATPHIHCTVFSPDGKYIFATDFSADRILRFVMHPDNPIPHASLEAVGIEADSGP
                     RHLTFSPNGKFAYLITELSGKVIAFSYDDGCLEQIQTITADTVAARGSADIHLSPDGKY
                     LYASNRLKEDGIAIFAVNPENGTLAKVGYQPTGIHPRNFNITPNGKYLLAACRDSNVIQ
                     VYKRNEVTGLLEDTHQDIVVDMPVCVQFVSSVNNL"
     CDS             complement(7414..10242)
                     /locus_tag="ctg20_10"
                     /transl_table=11
                     /translation="MKNLIALTLLLGGSTLLCAQKPAKTPATYKPVKSEMYRKGWIDFN
                     KNGVKDVYEDPSAPLEARIENLLQQMTLDEKTCQMVTLYGYKRVLKDDLPTPEWKELLW
                     KDGIGAIDEHLNGFQQWGLPPSDNAYVWPASRHAWALNEVQRFFVEDTRLGIPVDFTNE
                     GIRGVESYRATNFPTQLGLGHTWNRELIRQVGLITGREARMLGYTNVYAPILDVGRDQR
                     WGRYEEVYGESPYLVAELGIEMVRGLQHNHQVAATGKHFAAYSNNKGAREGMARVDPQM
                     SPREVENIHIYPFKRVIREAGMLGVMSSYNDYDGIPVQGSYYWLTTRLRGEMGFRGYVV
                     SDSDAVEYLYTKHGTAKDMKEAVRQSVEAGLNVRCTFRSPDSFVLPLRELVKEGGLSEE
                     VINDRVRDILRVKFLIGLFDAPYQTDLADADREVEKEENEAIALQASRESIVLLKNAGE
                     LLPLDINSTKKIAVCGPNANEEGYALTHYGPLAVEVTTVLEGIQEKTKGKAEVLYTKGC
                     DLVDAHWPESEIIDYPLTDDEQAEIDKAVENARQADVAIVVLGGGQRTCGENKSRTSLD
                     LPGRQLQLLQAIQATGKPVVLILINGRPLSINWADKFVPAILEAWYPGSKGGTALADIL
                     FGDYNPGGKLTVTFPKTVGQIPFNFPCKPSSQIDGGKNPGPTGNMSRINGALYPFGYGL
                     SYTTFEYSDLDITPRVITPNESATVRLKVTNTGKRAGDEVVQLYIRDVLSSITTYEKNL
                     AGFQRIHLEPGEAQELSFTIDRKHLELLDADMKWVVEPGDFVLMAGASSEDIRLNGTLT
                     VEDYQTRAKAIEAQKPAKRVSASTNPEDAENVLDEKINTAWQGNKGDYITFALKNGAKV
                     DKVAIAFTRDNNLPATFEIQLSGGGGQFLTVYSGTVSEYGKLISYPFKGTTASDLRIVL
                     NDDRVSIAEVKF"
     CDS             complement(11979..12176)
                     /locus_tag="ctg20_11"
                     /transl_table=11
                     /translation="MEWSNKIGVFTKTQGTKQQAIQKTPLVFMIYLPLIKSGPGENRTP
                     VQTRKPYAFYMLIFAFGFRA"
ORIGIN
        1 gctcatggca cggcctacga tattgccggg aaaggaatcg cctctgaaga ttcattccgg
       61 caggctatct atgtggcaat agatgtgttc cgtaaccgcc agcgtgagaa agaggcacat
      121 gcaaatccgc tgcgcaagca atattacgag aaacgtgacg atagcgacaa actgaaactc
      181 gatagtgtag aagaagattt gtagaatgac aaaagcggaa atacaacaag taaaattacg
      241 tttcggcatt atcggcaaca atgaagcgct gatgcgtgcc attgatatcg ctatccaggt
      301 agcgcccacc gacttgtctg tactgattac cggagagagt ggtgtgggaa aggagagctt
      361 tccgcagata atacaccagt acagccggcg caagcatgga cagtacattg ccgtgaactg
      421 tggagccatt cccgaaggga cgattgactc ggaactgttc ggtcatgaga agggcgcatt
      481 taccggggct atcggcgaac ggaaggggta tttcggtgag gccaacggcg gaacaatctt
      541 ccttgatgaa gtcggcgaat tgcctttgcc tacccaggca cgcttgttgc gtgtgctcga
      601 gagcggtgaa ttcatcaaag taggttcttc taaggtggaa aagaccgatg tgcgtattgt
      661 tgccgctacc aatgtaaact tgacacaagc cattgctgac ggacgttttc gtgaagactt
      721 gtattaccgt ttgaacacag ttcctattca ggtccctcca ttgcgcgaac gcggtgaaga
      781 cgtggtgctg ctgttccgaa agtttgcttc ggactttgca gaaaagtacc gtatgcctgc
      841 cattcagctg acggaagacg gcaagcaagt gttgctgggc tactcatggc cgggtaatgt
      901 gcgccagttg aagaatatca ccgagcagat atccatcatt gagaccaatc gtgaaatcaa
      961 tgcatccata ctgaagggct atctgcctga gcagaacaat atgcagcgcc tgcctgcctt
     1021 gtttggagtg aaggaggaca agagcttcgg gagtgaacgg gaaattctct accaggttct
     1081 gtttgatatg cgccaggatg taacggactt gaaaaagctg gtgcatgaga ttatggctga
     1141 aaggggaacg gtagccaatc cggcggttgc cacatcggcc tactatacgc cggctactcc
     1201 ggcggtggta cctccggtaa catccagtgt ccccaccatt atacatcctt cggtaaagcc
     1261 ggttactccg gtggacgatg atttccagga tacggaagaa tatgtggagg agtcactctc
     1321 cctggatgaa gtggagaaag aaatgatacg taaggcgctt gaaaaacatc acggcaagcg
     1381 taagagtgcg gctcaggatt tgaatatctc tgagcgtacg ttatacagaa agataaaaga
     1441 atatggattg gattaaaaaa gcggcatttg cttccttgtt ggtaagcttg ttatttctgg
     1501 tgaattcatg tagtatgaag ttgggacttg ctccgataag ctctatcgac tatacaaagg
     1561 taaaaacgat ttccattgcc gatttccaga accgggcaga gtatgtatat gcaccgctgg
     1621 caacagaatt taaccagaaa atgaaggata tgttcattca gcagactcgc ctgcaactgg
     1681 tgaattccgg aggagacctg gaaatagacg gagaaataac cggctacaat caatataatg
     1741 aatcggtgga tgccagcggc tactcttcga aggtgaaggt gacgctgact gtcaacgtgc
     1801 gctacaccaa taacacgaac catgaggagg actttgaaca gcagttctcg gctttccaga
     1861 cctatgattc ctcaaaattg ctgaccgaag tgcaggacca gctgataacc ttgatggtga
     1921 aagacattgc cgaacagatt ttcaatgcaa ctgtagctaa ctggtaaact catgacgcct
     1981 acccatttgc aacaatggat tcagcatccc gagacgctga atagggatac tttgtacgag
     2041 cttcgcacat tggtggcacg ctatccttat ttccagtcgc tccgtttgct ctatctgaaa
     2101 aacctctatc tgctgcacga catcaacttt ggcgcggagt tgcgcaaggc tgtgttgtat
     2161 gtggcagacc gtcgtgtgct gttttacttt atagagggtg accgctatac tttgaaatcc
     2221 cggaaggtct cgtcgctgtt ttccggcgat ttggagaaag agccgagtgt ggaccgtacc
     2281 ctttccttga ttgacgcatt tctggctact gttcccgaag agcattcaca gcatacggag
     2341 ctggattatg cggtggatta tacggcctat ttaatgcagg aagaacccgg tgtggatgca
     2401 gaagatgagt cggaagtgcc taaactgcgc gggcatgaat tgatagatga ctttatccaa
     2461 aagagtgagt cttcggatgc ctcggatacg agaagggagt ttcttgtaga gaaggaggaa
     2521 gagactgaag aagaggaaga accctcagta tcgccggtaa cggaagagtt ggacgatagc
     2581 tgttttacgg aaactttagc caaaatctat ataaaacagc accgatatga caaggcgctt
     2641 gaaattatta aaaaattaag tttgaattat ccaaaaaaaa atgcttactt tgcagaccaa
     2701 atcagatttt tggagaaatt gattattaac gctaaatcaa aataacaaaa tgtatttatt
     2761 attagttatc ttaatgctga ttgcatctgt gctgatgtgc ttcattgtat tgattcaaaa
     2821 ttctaaagga ggtggtctgg catcaggctt ttcatcatcc aaccaaatta tgggtgtgcg
     2881 caagactacg gactttttgg aaaaagcaac ctggactctg gcagctgtca tggtagtctt
     2941 cagtattgtt tctgcttaca ctattccttc ttccacaggc aagggcggtg atgtgattct
     3001 ggaacaggcg caacaagaag aaaaaactaa tccttataac atgcccgtag gtacagaagc
     3061 tccgcaatcg gaggcccctg cagctacaac tccggctgaa actcctgctc ctgcagcaga
     3121 agcccctgca gcagaataag ataaggatat tgcggatgac tcccgcttgg aaaaataaga
     3181 gaaaggttga tactgaaaag gtgtcagcct tttttcgttt tgatgaagta tttatttacc
     3241 tttgtcagca atttatgcaa tctgattaat aaattgaaat ccaaatagta caatgacaga
     3301 acaactcaaa cttaaattga atgattccaa ggctacccgt tggggggcat tggtgattgt
     3361 tgccttcacg atgatggcag cttattatgt aaacgacgtg gtagcaccgt tgaagacaat
     3421 gttggaaacg gacttggctt ggtcgagtac cgatttcgga ttctttaccg gtggttatag
     3481 ttttctgaat gtttttttcc tgatgttgat ttggggagga ttaatcctcg accgctttgg
     3541 tatccgtttc accggaaagc tggcaactat cctgatggtg ggtggtacag cacttgaata
     3601 ctatgcaatg acgggacttg ccggtgccga cgcgacttta ttcggaatca atgaaatatt
     3661 tggctataaa acgggtgtgt ttgttgcttt tgccggttat tccatttttg gagtaggagc
     3721 ggaggtcgcc ggtattacag tttccaaaat catagccaag tggtttaagg ggaaagagct
     3781 tgccacggct atgggggtac aagtcgcttt agcacgtatc ggttcgcaag ccggttatgc
     3841 cgtagccatt cctttggccc gcgctttcgg tatttccaca ccggtgttgt tgggtttggt
     3901 tctgttgttg ggcggtatga ttgctttctt cgtctttgca gtgatggaca agaagctgga
     3961 caaacagatg gaagctgctg ccattgctgc cggtacggaa gatgaggaag agaagttctc
     4021 ttttaaggat gtgaagaata ttctggtcaa tcccggtttc tggctgatag cattgctgtg
     4081 tgtattgttc tactcttgtg tattcccatt ccagaagttt gcttccgagt tgatgattat
     4141 caaatacggt atcaatgaga atgtggccgg tacatttgcc ggacttccgg cattgggagc
     4201 gctgattctg actccggtct ttggtggttt cattgacaag cggggcaagt ccgcatctat
     4261 catgctgctg ggctcggcca tgctgatatg tgtgcatttc atttatgcta ttcccgatat
     4321 aaactattgg ctggtagcta ttgtgctgat gataattttg ggtatcgctt tctcgctggt
     4381 accttctgcc atgtggccgg ctgtggccaa gatattcccg gtaagccagt tgggtacggc
     4441 atacgcattg attttcttta tccagaatat cggtctttgg ggtattccta cattgatagg
     4501 gtgggtgctt gatgcctatt gtatatccgg caagaaacca gatggaacga atatgtatga
     4561 ctatacggtg cctatgtgca tttttaccgg tattgcctgc ttgtccctta tagtggctct
     4621 actgctgaag aaggcagaca agaagtatgg ttataagctg gaagagccta atattcagaa
     4681 ataataggaa aagcggatac cgtatgatgg aaatacccga aggaaaagta agtctgttgg
     4741 acgctgttcc ggtccgctgt ggacatataa caaccgaatg ggaaggtgag tgcgccgtac
     4801 tcgcctaccc acggtttaaa tacgaatgga tgcgtcgttt tttattgccg aaggggatgt
     4861 ctcctgacat ccatgtgagg ctggaagaac acggtacagc tgtctggaat ctgatagatg
     4921 gacatcgtac cgtgcgcgaa atcatctctc tacttgccag gcactttggg gaggaagaga
     4981 attatattcc ccgggtcacc gcctacgtaa tgcagttgcg taaggatgga tttatccagt
     5041 tgacaatccg gaattagaat tcctttattc cctatccact tttatcaatc ctcccgttgc
     5101 cgtatcaaac agcactttga tggtagaatt cttgttgaac agtaccggtg cgaggtattc
     5161 tacggtgccg aattgggtaa tgggaagttg gtcgtcaaac aatttcttat tgttatacat
     5221 caatgtcact tgtgccttgc ccggaaggtt ataggctaca ccgtccactt tctttttgcc
     5281 ttcctcggtg gcagatacat cgggactttt gaggtcggtg acgctgatat aatacggttc
     5341 accggcaagg tcattattgg ccaccactcc cagctttcgg gaaaaacgga aagccacctc
     5401 atctttcatc tctttaggcg tcagccggat ggtgaatgtc ttgggttctt tctttatttt
     5461 gcccgagaac atttccgtca tagccgtttc ctgctggttc agattgtcaa gcatcagctt
     5521 gagttgggcg ccgtccttgg gcatattgtc tgcttcgccg cgcaggaggg cattcttgct
     5581 ttcgcggatg ctgtatattt ccttagccac cagctcggcc atcttggcac tggagttgga
     5641 catcagtatt tcttccgtca gaaaactgcg tgggtcaatg ctgctttcgg tggctttggc
     5701 ttcgggcgtc ttggcagcag gcttaccgct gaacggaatg ttgatggagc ggacaattcc
     5761 gtcttcggta agctccataa ggggtgctac ggtcttgtct ttcatcttca cgaaatagac
     5821 gttgtcctta tccggtacac cggctatgcg ggtttctatc ttatccagtg tccagaactc
     5881 ctcgggttcg gcagacacgt tgttgagacg cagatagcgg tcggcatatc tgcaaaattc
     5941 tccgggagtg taggtatgct tggtggcttg caatacgatt tctatttctg ttttgggtaa
     6001 catataagtc actccgtagt ctttgccacg catcacaccg gtggttacgt ctgtttgcgc
     6061 catggcagtg atagacaaga acagagctga gagcatcaat atattcttct tcataatgta
     6121 cattcgttta gactgattta gctaagggac aaagttaatg aagttatctt tgctaaatat
     6181 tgctttataa attattaaca gagctgacga actgtacgca aaccggcatg tcgactacaa
     6241 tgtcctgatg agtatcttcc aagagtccgg taacttcgtt tcgtttgtat acctgaatga
     6301 cattgctgtc gcggcaggcg gcaagcaagt atttaccgtt gggcgtgatg ttgaagttgc
     6361 ggggatggat gccggtgggc tgataaccta cctttgccaa ggtcccattt tcgggattca
     6421 cggcaaagat ggcgatgccg tcttctttca gacggttgct ggcgtagagg tatttcccat
     6481 ccggactgag gtggatgtct gcacttccac gggcggctac ggtgtcggct gtgatagtct
     6541 gtatctgttc caggcagccg tcgtcgtaac tgaaggcaat gaccttaccg gacagttcgg
     6601 tgatgagata ggcaaacttc ccgttagggc tgaatgtcag atggcgcggg ccggaatctg
     6661 cctcaatgcc aacggcttcc agagaagcat gaggaatagg gttgtcgggg tgcatcacaa
     6721 agcgcaggat gcggtcggca ctgaagtcgg tggcgaagat atactttccg tccggtgaaa
     6781 agaccgtgca atggatgtgg ggagtggctt gccgtatggc gtcgggaccg gtggcagagc
     6841 cttgaaagag cgtgtctgca ggagccaaag tgccgtcttt ctgtaaagga aagacggaca
     6901 tggttccacc gctgtagttg gcagtcaaca cttcccggcc attggtggcc acgtagcagg
     6961 ggtcggcgcc gaaggtggga acggtgttca gcaggcgcag ttctcccgtt tcccggtcga
     7021 aggcaaggga gctgagggct gctgtgctgt cgttcatttc actgacggca tagacaaatt
     7081 cgccatcttc cgaggggacg aggtaggagg gattgggcaa tgccgctgaa ctgagcggaa
     7141 cggctgttcc cgtctcctga ttaaagcgga aggtatagat acccttgctt gagccattcg
     7201 tgtaagtacc tattagcatg gcgagttcgt cctggtcacc gttagtgccc cttggagaag
     7261 agccacatgc tgtcaaacct aatccgagca tacagaaaag aagtgttttc attaatttaa
     7321 tgtgttaatg tgccaatatg ctaatgtgct aattggctgc gctgtatatg ctgcatggtc
     7381 attggtacat tagcatattg gcacattagc acattaaaat ttaacttcgg caatactgac
     7441 gcggtcatcg ttcagcacga tgcggaggtc gctggcggta gtgcctttga acggatagga
     7501 aatcagtttg ccgtattcgc tgacggtgcc cgaatatacg gtgaggaact gtccgccacc
     7561 gcccgagagc tggatttcga aggttgccgg caggttgttg tcacgtgtaa aggcaatggc
     7621 aactttatct accttggctc cgttctttaa ggcaaaggta atataatctc ccttatttcc
     7681 ttgccatgcg gtattgattt tttcgtcgag cacgttttcg gcatcctctg ggttggtgct
     7741 ggcactcaca cgctttgctg gtttttgggc ttcaatggct ttggcacggg tctggtagtc
     7801 ttctacggtc agcgttccgt tcaggcggat gtcttcggaa gaggcgccgg ccatgagcac
     7861 gaagtcgccg ggttccacca cccatttcat gtcagcgtcc agaagctcca ggtgcttgcg
     7921 gtcgatggtg aaggacagct cctgggcttc gcccggttcg aggtggatgc gctggaagcc
     7981 tgcaagattc ttttcgtagg tggtgatgct gctcagtacg tcgcggatat agagctgcac
     8041 tacttcatct ccggcacgtt tgccggtgtt ggtcaccttc aggcggacgg tggcagactc
     8101 gttcggggtg atgactcggg gggtgatgtc gaggtcggag tactcgaagg tggtgtagct
     8161 caagccgtaa ccgaaggggt agagtgctcc gttgatgcgt gacatgttgc ccgtaggtcc
     8221 cggattctta ccgccgtcta tctgtgaaga aggtttgcag gggaagttga aggggatttg
     8281 ccctacggtc ttggggaagg tcaccgtcag ctttccaccg gggttgtagt cgccgaagag
     8341 gatgtcggcc agggctgttc cgcctttgga gccgggatac caggcttcga ggatagcggg
     8401 gacgaacttg tctgcccagt tgatggagag cgggcgtccg ttgatgagta tcagtacgac
     8461 gggcttgccc gtggcttgta tggcttgaag cagttgcaac tgccgaccgg gcaggtcgag
     8521 gctggtgcgc gatttgtttt cgccgcaggt gcgttgtccg ccgcccaata ctacgatggc
     8581 aacatcagct tgacgggcat tttctacggc tttgtctatc tcggcttgtt cgtcgtcggt
     8641 cagcggatag tctatgattt cactttcggg ccagtgggcg tccaccaggt cgcagccttt
     8701 ggtgtagagc acctctgcct tgccttttgt cttttcttga atgccttcca gcacagtggt
     8761 cacttctacg gcaagtgggc cgtaatgggt cagcgcgtag ccttcttcat tggcattggg
     8821 accacagacg gcaatcttct tggtggagtt gatgtctaag ggcaatagtt caccggcatt
     8881 cttcagcaga acgatggact cgcgggatgc ctgcaaggca atggcttcgt tctcttcttt
     8941 ttccacttca cggtcggcat cggcaaggtc tgtctgatag ggggcatcga acagaccgat
     9001 gaggaacttt acccgaagga tgtcgcgcac gcggtcgttg atgacttctt cgctcagtcc
     9061 gccttccttc accagttcgc ggaggggaag gacgaaggag tcgggcgagc ggaaggtgca
     9121 gcgtacgttc agtccggctt ccacgctttg gcggacggct tctttcatgt ctttggcggt
     9181 gccgtgcttg gtgtagaggt attctacggc gtcactgtcg gatacgacgt agccacggaa
     9241 tcccatttcg ccacgcaggc gggtggtgag ccagtagtag ctgccctgca cggggatgcc
     9301 gtcgtaatcg ttgtacgaac tcattacgcc cagcatgcca gcttcccgga tgacgcgttt
     9361 gaaggggtag atgtgtatgt tttccacttc gcgcggcgac atttgcgggt ccacgcgtgc
     9421 catgccttcg cgggcgcctt tgttgttact gtaagcggca aagtgcttgc cggtggcggc
     9481 cacttggtgg ttgtgctgca agccgcgcac catttcgatg cccagttcgg ctacgaggta
     9541 gggagattcg ccgtaaactt cttcgtagcg tccccagcgc tggtcgcgtc ctacgtcgag
     9601 gatgggggcg tagacgttgg tgtagcccag catgcgggct tcgcgtccgg tgatgagtcc
     9661 tacttggcga atcagttcac ggttccaggt atgtcccagt cccagttggg tggggaagtt
     9721 ggtggcgcgg tagctttcca cgccgcgtat gccttcgttg gtaaagtcta cggggatgcc
     9781 gagacgggta tcttccacaa agaaccgttg cacctcgttc agtgcccagg cgtggcgcga
     9841 ggcgggccag acgtaggcat tgtccgaggg aggcagcccc cattgctgga agccgttcag
     9901 gtgttcgtcg atggcgccga taccgtcttt ccagagcagc tctttccatt cgggggtggg
     9961 gaggtcgtct ttcagtacgc gtttgtagcc gtagagggtg accatttggc aggtcttttc
    10021 gtccagcgtc atctgttgca gcaggttttc gatgcgtgct tcgagcgggg cggaggggtc
    10081 ttcgtacacg tctttcactc cgtttttgtt gaagtctatc caacctttgc ggtacatttc
    10141 acttttcacc ggcttgtagg ttgccggtgt tttggcaggc ttttgtgcgc agagcagtgt
    10201 gcttcctcca agcagcaggg ttagggcaat aaggttcttc atgatatgtt ctaaaaatct
    10261 cttggttatt attgtttctt ttgttgacaa aaatacggct aatgtgtgaa ataaagggat
    10321 aaaatagtcc gaagtatcgg cttttattgt ccgaagggtc ttcctcttac taaaaatatc
    10381 ctccaagacg ctaccgggga attcaaatca ttattagacg aaacatatca ttcactttta
    10441 aaaagaaaga gagaacacta taataacctg aaaagtagat gcaatcgcgg tgtatacaag
    10501 tattacggct acatctgtta aacgagggtg tatttatata ataggaatct gttggcggaa
    10561 ttgttgcttg tacggaagaa ctttcttttc aaccttggga tgtctaaacc caaccttggt
    10621 ttagacatcc caaggttggg tatggaaaaa ccaaagtttg ggatagattg cttccttaat
    10681 tctttccggt ttttcagtta acttcagaga ctttttccgt taacttccca tctcttttgt
    10741 gcaaatatcc attacagaag atagatattc cctcttgcag ggggtaattc cgtcaacgga
    10801 tactggcttt ggtagctgtt tgaacattga tgacaatggg gtgcacatat tctatgtatg
    10861 gaagattatt gtttttatca cgaaaagtca gtattagcta atatttgtaa atatatggtg
    10921 attgctaata aaagaatatg tatctttggg ccaaagaaag cggtagagga tgaaaaataa
    10981 agtagcattt atcccttttt caccctccct acttagcaat gagttacgca atcttttaaa
    11041 tttcagaccg ttacaaagtc atggggttga ctggatttga cagcgggcag aaatggtaag
    11101 taagcatgca gtgcgtcgtt gatttgcact ttaatctcag tcctcaaaat tttatctggc
    11161 gaaactcgtt acgctctcgc tgcttaatcg aagtatagta gattgaagct taatcccggc
    11221 accaggtgct gggacgtgac atcactcgga agctgttgct ccgaagcatt ccgataaagt
    11281 ggtgcagtca aatcggggat agttcgtgtc agcctcgtgg cgcgggtgaa aatttagagg
    11341 ataaggcaac ggttgatggc tttggttctg ccgctgcacg aaaatttagg caaagataag
    11401 catgtagaaa gcttatgatt tcctcgtttg gacgagggtt cgattccctc cagctccaca
    11461 aataagattg ataatcagat tgttacagga tttacacccc gaaatacacc ctaaaataaa
    11521 aagtgatagt ctgattatca ttctctatat caagcactac ctacaagtct taaataattt
    11581 aactattatg atgccttgtg gtattctatt atattttttg ctgttttgtt tgttcttatc
    11641 aaataaatac gtaactttga aatatcattt tgggcttgac tggaattgac agcgagttgg
    11701 aatggtatgt aagcatgcag tgggtcggta atttccactt aaatctcagt tatcaaaatt
    11761 ttatctggca acgaaaatta tgctctcgct gcttaatcga agtatagtag attagcttta
    11821 tttctgccaa agtggtggaa acgagatgtc gctcaaaagc tcttgctccg aagcgtttga
    11881 taaagcggca cagcaaaatc ggggatagtt tgagttcttc tccatagctc ttacgaaata
    11941 ttaggagata aggcataggt tggtggcttt ggtcttgctt atgctcgaaa accgaaggca
    12001 aagataagca tgtagaaagc atatggtttc ctcgtttgga cgggagttcg attctcccca
    12061 ggtccacttt tgatgagcgg taagtatatc atgaaaacta atggtgtttt ctgtattgct
    12121 tgttgttttg taccttgagt ttttgtgaat accccgattt tgttactcca ttccatcccc
    12181 tttgaaattt taaagtatta aataatctaa tcctttctgt aagcgattta agttgttttt
    12241 ctaaaattg
//
