LOCUS       c00221_gnlPro..        13565 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CHNEIIPF_221.
ACCESSION   c00221_gnlPro..
VERSION     c00221_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 00:57:35
            Original ID  :: gnl|Prokka|CHNEIIPF_221
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13565
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13565
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[714:3565]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      715..3565
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13565
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13565
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             3..194
                     /locus_tag="ctg221_1"
                     /transl_table=11
                     /translation="RSTTVFKTAAIDHSATSPKLLFQKCFSFKAVQRYKSFFILQTFLH
                     KNRAIIPKFLFIPTTERT"
     CDS             715..2838
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg221_2"
                     /sec_met_domain="Gly_radical (E-value: 1.2e-46, bitscore:
                     148.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1147.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LQGPTERTKRIWDICLKALEEERNNNGVRSLDNTTVSTITSHKAG
                     YIDKDNELIVGLQTDELLKRSIKPFGGINVVAKACRENGVEVDDKVKDIFTHYRKTHND
                     GVFDVYTEEIRSFRSLGFLTGLPDNYARGRIIGDYRRLALYGIDRLIEAKQEDLRNLTG
                     PMTEARIRLREEVAEQIKALKDIKVMGEYYGLDLSHPATSAQEAVQWVYMAYLAAIKEQ
                     DGAAMSLGNVSSFLDIFIEYDLAHGKINETFAQELIDQFVIKLRMVRHLRMQSYNDIFA
                     GDPTWVTEAIGGRFNDGRVKVTKTSFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKDFC
                     AKVSVDTSSIQYENDNLMREVRNCDDYGIACCVSYQAIGKQIQFFGARANLAKALLLAI
                     NGGRCENTGTVMVKGIPVLTGETLKFEEVMANYKKVLTEIARVYNEAMNIIHYMHDKYY
                     YEKAQMAFIDTDPRINLAYGVAGLSIAIDSLSAIKYAKVTARRNEIGLTEGFDTEGSFP
                     CFGNNDDRVDHLGVDLVYYFSEELKKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGR
                     AKGVAFAPGANPMHGRDKNGAIASLSSVAKLRYRDSQDGISNTFSIVPKSLGPTPEERV
                     ENLVTMMDGYFTKGAHHLNVNVLNREMLEDAMEHPEKYPQLTIRVSGYAVNFVKLSREH
                     QLEVISRSFHERM"
     CDS             2840..3565
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 75.5;
                     E-value: 1.7e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg221_3"
                     /sec_met_domain="Radical_SAM (E-value: 3.4e-31, bitscore:
                     99.5, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCPFRCLYCANPDTIDVKGG
                     TPTTPEEILQMAISQKAFFGKKGGITFSGGEPTLQAEALIPLFKELKANGIHICLDSNG
                     GIWNEKVEELFSLTDLVLLDIKQFNPERHRTLTGRSNEQTLRTAAWLEEHEHPFWLRYV
                     LVPGYSDSEEDTRLLGESLGKYQQIQRVEILPYHRLGVHKYEAMGWDYKLKEVKENTPE
                     QLERAEKLFKEYFTNVITN"
     CDS             complement(3634..5610)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 84.8; E-value: 1.1e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg221_4"
                     /sec_met_domain="Fn3-like (E-value: 4.1e-27, bitscore:
                     84.8, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 3.8e-70, bitscore:
                     227.3, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 1.4e-52,
                     bitscore: 169.2, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNVIGVKDIRRYQELALQSRLRIPLIFGLDVIHGYRTGFPLPLA
                     EAASFDLAMIEEAARYNALESAADGLNWVFAPMVDISWDARWGRVMEGAGEDPYYGSRV
                     AEARVRGLQGDDLADTTTVMACMKHFAGYGAPIAGKEYNSVDMSMGHFANFYMPPYKAA
                     IKVGAATVMSAFNDFNNIPCTANDFLLNRLLREQWGFKGFVVSDYNSVEELVNHRYAVD
                     KKDAAAKALNAGLDMEMVSTCYLTYLKELVQEGKVKESVLDDAVRRILEKKYELGLFED
                     PFRYCNPERAARILNAPEVRNASLRMAERSVVLLENRESVLPLTAQTRKIALIGGLSKS
                     QYDMAGAWAATTDRNKVVTLYDALVRKGLEVSYAEGYDMKSNQLTGLQEALQAAEASDV
                     IVVAVGERFGQSGEKASKVNIAIPEGQQKLVSELAKTGKPVIALVMCGRPVIFNEIREH
                     ADAVLCTWWLGSEAGNAICNVLWGEYNPSAKLPMTFPAHVGQIPIYYQNKSTGRPTALK
                     QTYKASYIDASTEPAYPFGYGLSYTDFGYSDLKLLPGKAAGVHTEVSVKVTNTGKCAGE
                     EVVQLYVQDKVASVTRPIKELKGFRKIHLNVGESKTVAFQITDDALGFYDNEMNYMVEP
                     GDFVFMVGGSSDDVQQITYNLKE"
     CDS             complement(5869..8007)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 80.3; E-value: 2.8e-25)"
                     /gene_kind="other"
                     /locus_tag="ctg221_5"
                     /sec_met_domain="Fn3-like (E-value: 1e-25, bitscore: 80.3,
                     seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 4.9e-47, bitscore:
                     151.3, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 5.9e-51,
                     bitscore: 163.9, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LARDAKARGVSILLGPGVNIYRSPLCGRNYEYFGEDPYLTGETAK
                     EYILGVQEEGVMATVKHFAANNQEWSRHHASSDVDERTLQEIYFPAFRKAVQEAGVGAV
                     MDSYNPLNGVHATENSWLNIDVLRKQWGFKGILMSDWTSVYSGVGAANGGLDLEMPVGK
                     FMTREILIPAIENGIVKEETIDAKVRHILQTLIAFGALDTPREDKSIDKDNAQSKEIAL
                     DLAREGVVLLKNDNGTLPYRNGRTLVIGPNADIIPTGGGSGFVTPYSVVSLYDGMVQLK
                     GGRQIELLSDSILYKDMSQQIYTDGSFTQNGFKGEYYNTRNLTGELFQAAIEPAIDHAW
                     KYGAPFDGMPVDQFSARWTGVYKADKDGTVKFQLAGDDGYRLFVNDKLITGDWGNHSFS
                     TRSAFMQVSAGEIYRLRIEYFDNVGEATVSFQAGMMDEERLASSLKHARNVIVCAGFNS
                     STEGEGFDRPFALSYGQEYLINKVASLHDNVAVVVNAGGGIDFRNWGQSVQAILMAWYP
                     GQEGGKALAEIITGKLSPSGKLPVSIEEKWEDNPVYGNYYDNRNVPHKRVQYAEGVFVG
                     YRGYDRNGKQPLYPFGYGLSYSSFEYSNLSVEKTGGSRVTVSFDIKNTGKMDAAEAAQV
                     YVRDVECSVPRPLKELKGYDKVYLKKGETKRVRILLDEEAFAYYDVESHRFVVEKGTFE
                     ILAGPSSADLPLKATVVL"
     CDS             8083..8298
                     /locus_tag="ctg221_6"
                     /transl_table=11
                     /translation="LSIVTYALRTIGHPDFGYAKPGYSPDIKRFGTGNVIDFFFQRHLR
                     NQLPGTLLHLGSNTHLCFCRDCTTKQ"
     CDS             8276..8518
                     /locus_tag="ctg221_7"
                     /transl_table=11
                     /translation="VIAQQSNSPLKATFFLIFILSILLRVCYIAGHVPTYFLSSQSIKN
                     RVPSSTNEETRPKVIKKILNLQESGQKHVCPAINK"
     CDS             complement(8508..9833)
                     /locus_tag="ctg221_8"
                     /transl_table=11
                     /translation="MKERMEDELWLKKIKDKLEDYSEPLPVAGWERLEKELSVSGAPIT
                     GPHRMIPFRRWAVAAAAVLLVAVSSVSLWLLQSPVGNEMRHTSVPALAVAPDVLPEQTV
                     PAIRTNSIEPAYRAHGNASAPNKEASHPLVAQHIRISVGEEQQEEMLPVETADEVVGIG
                     QQAEEPVVEDTDHETTMQTEEPETREDRYRPSGRDKLHLPEKNSSGRDAKGWAVGLSVG
                     NTGGFSLANEGEANVMSDYMPGSPIYGGNVDLSSTANGIVTIPDGQELVFKDGMPYLQR
                     REKKIADIDHKQPLSFGVSVRKNLAKGFSVESGLTYTYLASDVRYEGSSEKISQKLHYI
                     GIPVRANWNFVDAKNFTMYVSAGGAIEKCVYGKIGTESETVKPVQLSVMGAVGAQYNIS
                     NRVGLYVEPGVSYFFDDGSSIQTIRKENPCNFTLQAGIRLTY"
     CDS             complement(9834..10244)
                     /locus_tag="ctg221_9"
                     /transl_table=11
                     /translation="MHDGFLKLFDSFDKFTWRGEGSLRAWMERVMVNTVLQYLRKNDVM
                     NQSSALENAPEAYEEPEGSSIDVIPQKVLMQFISELPAGYRTVFNLYIFEEKSHKEIAR
                     LLGINEKSSASQLTRAKATLAAKVREWMKRND"
     CDS             10563..11261
                     /locus_tag="ctg221_10"
                     /transl_table=11
                     /translation="MKKLRMTLATSMLLFLTAIVLQSCLDDWDDKYDTLFAVGTVKVIE
                     GKDYYFSLDEGSKLYPSDTTYVHDYAVTDGQRAFIYFRELEEKLPGYEYNAQIKHIENI
                     LTKDIYSMPAEKADSIGDDNINATDLWITGEYLNIKYQFYHSNNEDKKHMLNLVINEAS
                     TGENDKPDYVNLEFRHNAYNDSQLTLGTGLASFKLDTEQLKEKKGLNIRVKSLYDGERF
                     MTIDIKKENN"
     CDS             complement(11349..12023)
                     /locus_tag="ctg221_11"
                     /transl_table=11
                     /translation="MPYNMGTLFWQHNDCWPVASWASRDYYGRWKAQHYYTRKVYDDIL
                     ISPVVEGDDLKVYAVSDRLENTSGRLQLQVCRFDGTVVYHWDKSVGISGNDSRVCFSAP
                     LAKLLEGADRGTVYVRVDYTDKSGRVYHNNYCLDKQKNMNYPKVDLQTEVRSIEGGYEV
                     TVSTDKFARAVCLSVADNESVYSDNYFDVQPKSSVQVQVRTRLSAEAFNASLRLTCLNN
                     EF"
     CDS             12174..12446
                     /locus_tag="ctg221_12"
                     /transl_table=11
                     /translation="MGHHHLGTYIPVFGVRSIALDGVELWKRLKAVLAEKAGFLAVIIG
                     NGCFTMPDTPIVTVPVSSTGHLSLECERRRRPIEGSGCILPDHPG"
ORIGIN
        1 ctcgcagcac aacggttttc aagaccgccg caatcgacca ctctgccacc tctccaaaac
       61 ttctttttca gaagtgcttt tcttttaaag cggtgcaaag atacaaatca ttttttattc
      121 tacaaacttt tctgcacaaa aacagagcaa ttataccaaa attcttgttt atacccacta
      181 cggaacgaac ataacggcat ttaggctatt tgttgaaatt tatcaagggc aagacagagt
      241 tttataactt actggctatc agtatattta caaagagcca cattcagtat acgattgaac
      301 cctattcagt atacgactga atggcattca ctatacgact gaattaggtt cagaatacga
      361 ctgttcctta aacctacatc atttgtaaat aatgcagatt attattcggt tcttgtttca
      421 attcataaac cacatataaa gaaagtatta acatctctac tcccccggac attcactacc
      481 taataatagt tattttatgc tgttcaacat aaaaagagaa gtatctctta taaaattacg
      541 gaatttattc agtatttttg cgcgctctaa aggataacat tatctaacct actaacaaaa
      601 acaaatttta tggaattgaa caaaaccttt accaatgggc tttggaataa agaaatcaat
      661 gtcagtgatt tcgtcagtaa aaacatcgca ccctataccg gggatgcatc tttcttgcag
      721 ggacctaccg aacgtaccaa acgtatctgg gacatctgtc tgaaggctct cgaagaagaa
      781 aggaacaaca atggcgtccg ttcactggac aataccaccg tatctaccat cacttctcat
      841 aaagccgggt atattgataa ggacaatgaa cttattgtcg gtttgcagac tgatgaactg
      901 ttgaaacgat ccatcaaacc tttcggaggc atcaacgtgg tagcaaaagc atgccgtgaa
      961 aacggagtgg aagtggacga taaagtaaaa gacatcttca cccattaccg caaaacacat
     1021 aacgacggcg tattcgatgt atataccgaa gaaatccgtt ccttccgctc actgggattc
     1081 cttaccggat tgcccgacaa ctatgcccgc ggacgtatca tcggcgacta ccgccgattg
     1141 gctctctacg gcatcgaccg tctgattgaa gccaagcagg aggacttgcg caacctcacc
     1201 ggcccgatga ccgaagcacg catccgtcta cgcgaagaag tggcagaaca aatcaaagct
     1261 ttgaaggaca tcaaggttat gggcgaatat tacggactcg acctcagcca tccggctaca
     1321 tcagctcaag aggccgtgca atgggtatac atggcatatc ttgctgccat caaagagcag
     1381 gacggagcag ccatgtcact gggtaacgta tcttcgttcc tcgatatatt cattgaatac
     1441 gatctggctc acggaaaaat caatgagacg tttgcacagg aactgataga ccagttcgtc
     1501 atcaagctgc gcatggtacg ccatctgcgt atgcaatcat acaatgatat ctttgccggt
     1561 gacccgactt gggtgaccga agccatcgga ggacgcttca atgacggacg cgtgaaggtc
     1621 accaagactt ctttccgctt tttgcagacg ctatacaacc tcggtccttc tccggaaccg
     1681 aacttgaccg tattgtggag tcccgaactg ccggaaggct tcaaggattt ctgcgccaaa
     1741 gtttctgtag ataccagctc catccagtac gaaaacgaca acctgatgcg tgaagtgcgc
     1801 aactgcgacg actacggcat cgcctgctgt gtatcctacc aagccatcgg caaacaaatc
     1861 cagttcttcg gcgcacgtgc caaccttgcc aaggccctgc tgctcgccat caacggtgga
     1921 cgttgcgaaa ataccggaac tgtcatggtg aaaggtattc ccgtattgac cggtgagaca
     1981 ttgaagtttg aggaagttat ggccaactac aagaaggtac tgactgaaat agcccgtgtc
     2041 tacaacgagg ccatgaatat catccactac atgcatgata agtattatta tgagaaagcc
     2101 cagatggcat tcatcgatac cgacccacgc atcaatctgg catacggtgt tgccggcctt
     2161 tccatcgcca tagactcact gtccgccatc aaatatgcca aagtcactgc acgccgcaac
     2221 gaaatcggcc tgaccgaagg tttcgacact gaaggttcat tcccctgctt cggcaataat
     2281 gacgaccgtg tggaccacct gggagtagac ctcgtttact atttcagcga agaactgaaa
     2341 aagctgcctg tctacaagaa tgcccgtccc accctttcct tgctgactat cacctccaac
     2401 gtgatgtacg gcaagaagac cggtgccact ccggacggac gcgccaaagg tgttgccttt
     2461 gctccgggtg ccaacccaat gcacggacgt gacaagaacg gtgccatcgc ttccttgagc
     2521 tccgtagcca aattgcgcta ccgcgactcg caggacggca tcagcaatac gttctccatt
     2581 gttcccaaat cactgggccc gacaccggaa gaacgtgtag agaacctggt aaccatgatg
     2641 gacggctact tcaccaaagg tgcccaccat ttgaacgtaa acgtactgaa ccgcgaaatg
     2701 ctggaagatg ccatggaaca tcctgaaaag tatccgcaac tcaccatccg cgtttccggc
     2761 tatgccgtga acttcgtgaa gttgagccgc gagcatcagt tggaagtcat cagccgttca
     2821 ttccacgaaa gaatgtaata tgataaatgt acactcctac gaaagtatgg gaacattcga
     2881 cgggccgggt ctccggctcg tcgttttcct gcaaggatgt ccgttccgtt gtctgtattg
     2941 tgccaatccg gatacgattg atgtaaaagg aggcactccc accactccgg aagagattct
     3001 gcaaatggct atcagccaaa aggcattctt cgggaagaaa ggaggtatta ctttctccgg
     3061 cggtgagcct accctgcaag cagaagcgct gattcctctt ttcaaggagc tgaaggcgaa
     3121 cggcatccat atctgtctgg acagtaacgg aggcatctgg aatgaaaagg tggaagagct
     3181 ctttagcctg actgacctcg tgctgctgga catcaagcaa ttcaatcccg aacgccaccg
     3241 tacgctgacg ggacgaagca acgaacagac actccgcacc gctgcctggc tcgaagaaca
     3301 tgaacacccc ttctggctgc gctatgtact ggtccccggt tacagcgatt cggaagaaga
     3361 cacccgcctg ctgggtgaaa gtcttggcaa ataccagcag atacaacggg tggaaatact
     3421 tccttatcac cgtctgggtg ttcacaaata cgaagccatg ggatgggatt acaaattgaa
     3481 agaagtgaag gaaaatactc cggaacaact ggaacgggca gaaaaactgt tcaaagagta
     3541 tttcacgaat gtgataacca actaaaacag aaaagcaagg ctgtccggat atgattccag
     3601 acagccttgc ttttcattta tagggtaaga atcctattct ttcaagttat aggtaatctg
     3661 ctgtacatca tcactactgc cacccaccat aaagacgaaa tcaccaggtt ctaccatata
     3721 attcatctca ttgtcataga atcccagtgc atcgtcagtt atctgaaaag ctacagtttt
     3781 gctttcaccc acattcagat gaattttcct gaagcccttc aattccttta tcggacgcgt
     3841 aacagaggct accttatcct gcacatacaa ttgaactact tcctctcctg cacacttacc
     3901 ggtattagtc acttttaccg acacctccgt atggacgcct gcagccttgc ccggcagcag
     3961 tttcaaatca gaatatccaa aatccgtgta cgaaagccca tatccgaaag gataggcagg
     4021 ctcagtggaa gcatcgatat aagatgcctt ataggtctgt ttcaatgcgg tagggcggcc
     4081 ggtgctctta ttctgataat aaatgggaat ctgtcctacg tgtgcaggaa atgtcatggg
     4141 caatttagcc gaaggattat actctcccca caacacattg catatggcat tgccggcctc
     4201 acttcccagc caccaagtac acagtaccgc atcagcatgt tcccttatct cattgaagat
     4261 taccggacgc ccacacatga caagagcaat gacaggtttt ccagtctttg ccagttccga
     4321 caccagcttc tgctgcccct cgggtatggc tatattcact ttggaagcct tctcgccact
     4381 ctgaccgaat ctctcgccta ccgccacaac aatgacatcc gaagcctcag cagcctgtaa
     4441 tgcttcctgc aatccggtca actgattgct cttcatatca tagccttcag catagctcac
     4501 ctccagtcct ttccggacca atgcatcata taaggtcacc actttgttcc ggtccgtagt
     4561 ggcagcccaa gcacctgcca tatcgtactg ggattttgag agtcctccta tcaaggctat
     4621 cttcctcgtc tgtgccgtca acggaagcac agattcccta ttctccagca atacaacgga
     4681 acgctcggcc atacggagcg aagcattacg gacttcgggc gcattgagta ttctggccgc
     4741 tctttccgga ttacagtagc gaaaagggtc ctcaaacaat cccaactcat atttcttctc
     4801 caatatacgc cgtactgcat catcaagcac actctccttt actttccctt cttgaacaag
     4861 ctccttcaga taagtcaagt agcaggtact taccatctcc atgtccagac cagcattcag
     4921 cgctttggct gcggcatctt tcttgtcaac agcataacgg tggttcacca attcctctac
     4981 cgaattataa tcggacacaa caaatccctt aaatccccac tgctctctca atagccggtt
     5041 gagcaagaaa tcattggcag tacaaggaat attattaaaa tcattgaaag cactcatcac
     5101 ggtagctgct cctaccttta tggccgcctt atagggaggc atataaaaat tggcaaagtg
     5161 gcccattgac atatccacac tattatactc ctttcctgct atcggtgcac catatccggc
     5221 aaaatgtttc atacatgcca tgacagtcgt cgtgtctgcc aaatcgtctc cttgcaagcc
     5281 tctgacacgc gcctccgcta cccgagaacc ataataaggg tcctcaccgg ccccttccat
     5341 gacgcgtccc caacgtgcgt cccacgaaat atccaccatc ggggcaaaaa cccagttcaa
     5401 accatcagcg gcactttcca aagcattgta gcgtgcagct tcctcaatca tggccaaatc
     5461 gaaacttgca gcctcggcaa gcggaagcgg aaatccggta cgatagccgt ggataacatc
     5521 cagtccgaaa attaaaggaa tgcgcaaacg cgattgcaaa gcaagctctt gataacggcg
     5581 tatatccttt actcctatca cattcagcat agagcctatt ctgccttgcc ggacatactc
     5641 ttctttagga atatttccac cgtcgggtcc ggtaaaattc cctcggtagg tgcattgtgc
     5701 aagctggcct atcttttcat ccagcgtcat ctgcttcatc aagcttgaga tgaatttctc
     5761 cttctccgta gtttgtgccg aggtaaaggt gttaccaagt ccccacagac aaaccatcag
     5821 tattattatc tttttcatac tgccattctt gttttgatat ttattttatc ataaaacaac
     5881 agttgccttc aatggtaaat cagctgaaga aggacctgcc agaatctcaa aagtcccctt
     5941 ttccactaca aaccgatgtg attccacatc atagtaggca aaggcttcct catccagcaa
     6001 tatccgaacg cgcttggttt cacccttctt caagtaaacc ttatcgtagc ctttcaactc
     6061 cttcaatgga cgcggaacag aacattccac atcccgcaca tatacctgag ccgcttccgc
     6121 agcatccatc tttccggtat tcttgatgtc aaagcttacc gtaacccggc ttccccccgt
     6181 cttctcaaca ctcagattac tatattcaaa actactgtat gacagtccat acccgaaagg
     6241 atagagcggc tgctttccgt tccggtcata tcccctataa cctacgaaaa caccttcggc
     6301 atactgcacc cgtttatgag gtacattgcg attgtcataa taattaccat ataccggatt
     6361 atcttcccat ttttcctcga tgctgactgg tagtttgcca cttggcgaaa gcttgcccgt
     6421 aatgatttcg gcaagggcct ttccaccctc ctgccccgga taccatgcca tcaaaatagc
     6481 ttgtacactc tgcccccaat tgcggaaatc tattccacct ccggcattca ccaccacagc
     6541 cacattatca tgaagtgaag ccactttatt aatgagatat tcctgcccgt atgacaatgc
     6601 aaacggacgg tcgaaccctt caccttctgt actgctgttg aacccggcac atacaataac
     6661 attcctggca tgcttcagtg aagaggccaa acgctcctca tccatcattc ctgcctggaa
     6721 actgacagtc gcctcaccca cattatcaaa atattcaata cgcaaccggt atatctcccc
     6781 tgcactgacc tgcataaatg cactgcgggt actgaatgaa tggttccccc aatctccggt
     6841 aatcagctta tcgtttacaa acagacggta tccgtcatcg ccagccagct ggaacttgac
     6901 agttccatcc ttgtcagcct tgtaaactcc cgtccaacgg gcagaaaact gatctaccgg
     6961 catgccgtcg aacggtgcac cgtatttcca ggcatggtct atggcaggct ctatggcagc
     7021 ttgaaagagt tctccggtaa gattacgagt attataatat tcgcccttaa aaccgttttg
     7081 cgtaaaactg ccatccgtat aaatctgttg ggacatatcc ttataaagaa tgctgtcaga
     7141 cagcagctct atctgtctgc cgcccttcaa ctgaaccata ccgtcataga gtgacactac
     7201 cgaataaggg gtgacaaatc cgcttcctcc tcctgtggga ataatatcgg cattaggccc
     7261 gattaccaat gttctaccgt tccggtaagg caacgtaccg ttatcatttt tcaataagac
     7321 tactccttct ctcgccaagt caagtgcaat ttccttagac tgtgcattgt ctttatcgat
     7381 agatttatct tctctcggag tatcaagtgc tccaaaagca atcaatgtct ggagtatatg
     7441 ccggactttg gcgtcaatgg tctcttcctt cacgatacca ttctctattg ccggaataag
     7501 aatttccctg gtcatgaatt taccgacggg catttccaaa tccaaccctc cattagcggc
     7561 tcccacacca gaatatacag atgtccagtc agacatcagg atacctttaa atccccactg
     7621 cttgcgtaat acatcaatgt tcagccagct gttttcggtg gcatgtaccc cgttcagcgg
     7681 attatagcta tccataaccg cccctactcc tgcttcctgc acagcttttc ggaacgcggg
     7741 aaaataaatt tcctgcagcg tgcgttcatc cacatctgag ctggcatgat gtctgctcca
     7801 ctcctggtta ttggccgcaa aatgcttcac cgtagccata actccctctt cctgcactcc
     7861 caagatatat tctttagcag tttcgcccgt caaataaggg tcttcaccaa aatactcata
     7921 gtttcgcccg catagaggag agcggtagat attgactcca ggccccaaca gaatacttac
     7981 cccacgggcc tttgcatccc gggccaaacc atgtcccagc tctctagcca acttacggtt
     8041 ccatgtcgaa gccgacaaga tgccacaagg atacaaggta ctttgagtat tgttacgtat
     8101 gccttgcgga ccatcggcca tcctgatttc gggtatgcca agccggggta cagcccggat
     8161 ataaaaagat ttgggaccgg aaatgtaatc gattttttct tccagcgtca tttgagaaac
     8221 caactccctg gcacgctgct ccacctgggg agtaatacac acttgtgctt ttgccgtgat
     8281 tgcacaacaa agcaatagcc cgcttaaggc tactttcttt ttaatcttca ttttgtctat
     8341 tttactacgt gtttgttata ttgccgggca tgtcccgacc tactttcttt cttctcaatc
     8401 aataaaaaac cgtgtccctt catccaccaa cgaagaaaca cggccgaaag ttattaagaa
     8461 aattctgaat ctacaagaaa gtggacaaaa acatgtctgt cctgctatca ataagtaaga
     8521 cgtataccgg cctgcaacgt aaagttacac gggttctcct tgcgtatagt ctgtatcgac
     8581 gaaccgtcat caaagaaata agatactccc ggttccacat acaggcccac cctattgctt
     8641 atgttatact gggcaccgac agcacccatg acagaaagct gtaccggttt cacagtctca
     8701 ctctcagtac caatcttgcc atacacacat ttttcaatgg caccccccgc cgaaacgtac
     8761 atcgtaaagt tctttgcatc cacaaagttc cagttggccc gtaccggaat gccaatataa
     8821 tgcagcttct ggcttatctt ttccgagctg ccctcatacc ttacgtcaga agcaagatag
     8881 gtatacgtca gcccgctttc cacagagaaa cccttcgcca agtttttccg caccgaaaca
     8941 ccgaaactga gcggttgttt atggtctata tccgcaattt tcttttcgcg tctttgcaga
     9001 tagggcatac catccttaaa aaccagttcc tgcccgtcgg gaatagtaac aatgccattg
     9061 gccgtagagg ataaatctac gttaccgcca taaataggac ttccaggcat gtagtccgac
     9121 atcacattcg cttccccttc attcgccaat gaaaaacctc ccgtatttcc tacggacaag
     9181 ccaaccgccc atcctttagc atccctacca gaactgtttt tttccggaag atgcagtttg
     9241 tcccggcctg acggacgata gcggtcttcc cttgtctccg gttcctcggt ctgcattgta
     9301 gtttcatggt ccgtatcttc cactaccggt tcttccgcct gctgtccaat accgacaacc
     9361 tcatctgcag tttcaaccgg cagcatttcc tcctgctgtt cttcgccaac cgatattctg
     9421 atatgttgtg caaccaaagg gtgacttgcc tccttattgg gcgccgatgc atttccatgt
     9481 gcccgataag caggctctat ggaattagtc cgtatggcag gtactgtctg ttccggcaag
     9541 acgtccggag ccacagccaa agcgggcact gacgtatgcc gcatttcatt ccctaccgga
     9601 ctctgcaaca gccacagact gacggacgaa accgccacca gcaacacagc tgccgcggcc
     9661 accgcccagc gacggaaagg tatcatccta tgcggtccgg ttatcggagc tccggaaacg
     9721 gacaattcct tctccaaccg ctcccatccg gcaaccggca gcggttcgga atagtcttcc
     9781 agcttgtcct ttatcttttt caaccacaat tcatcttcca tacgttcctt catttaatca
     9841 tttcttttca tccactcacg tacttttgcc gctaaagtcg ctttagcacg cgtcaactgc
     9901 gaggcagagg atttttcatt aattcccaat agtcgagcaa tctccttatg ggatttctct
     9961 tcaaaaatat ataagttgaa tacggtacga tagccggcag gcaattcact gataaactgc
    10021 attagtacct tttgaggaat gacatctatt gacgaacctt ccggttcctc ataagcttca
    10081 ggtgcattct ccaaggccga tgactgattc atcacatcat ttttccgcaa atactgcaac
    10141 accgtattca ccattacgcg ttccatccat gcccgcagag aaccctctcc ccgccaagtg
    10201 aacttatcga aagaatcaaa aagtttcaga aaaccgtcat gcatcaggtc ttgggcagtc
    10261 tcccggtcac ctgcataacg aaggcatacg ctgagcatgc gtcccgcata gcgctcatac
    10321 agttctttgc gggcaagatt gtctccttgc ctacagcgtt ctgccaattc ctgttcttcc
    10381 attctctctt ttaacacgtg tttaccctat aaatgcaatc ggcgcaaaaa tactgcatca
    10441 ggcagagaag aaaatcatac tttcatttct ttaacagtat actacgcagt atttagcttt
    10501 tcaccgcatt ttctgaatac aaaaataagt tttaaacaga aaagagctaa aacctaccac
    10561 ttatgaagaa actgagaatg acattggcaa catccatgct tttattcctg actgccattg
    10621 tattgcaatc atgcctggac gattgggatg acaaatatga cactttgttc gccgtaggta
    10681 cggtaaaggt catcgaagga aaagactact atttctcact ggacgaaggc agtaaactat
    10741 atcccagtga cacaacctat gttcacgact atgccgtaac agacggccag agggctttca
    10801 tctacttccg cgaactggaa gagaaacttc caggctacga atacaatgcc caaataaagc
    10861 acatcgaaaa tattctgacc aaagacatct actccatgcc tgccgaaaag gcggacagta
    10921 tcggagacga caacatcaac gccacggatt tatggattac gggtgagtat ctgaacatca
    10981 agtatcaatt ctaccacagt aacaacgaag ataagaagca catgctgaac ctggtcatca
    11041 acgaagcatc caccggcgag aacgacaaac cggattacgt caatctcgaa ttccgccaca
    11101 atgcctacaa tgacagccag ctcacactgg gcaccggact ggcctccttc aagctggaca
    11161 cggaacagct gaaagagaaa aaaggactga acatccgcgt caaaagtcta tatgacggtg
    11221 aacggttcat gaccatagac attaaaaaag aaaacaacta aatctcctga aaacacattt
    11281 ttcaacatct caatgagaag cggagtaaca tttcaatatg ttgctccgct ttgtttttcc
    11341 ataacttatc agaattcatt gttcaagcaa gtcagcctca acgaagcgtt gaacgcttcg
    11401 gcagacaatc gcgtcctgac ctgtacctgc acgctgctct tcggctggac atcaaaataa
    11461 ttgtcgctat atacactttc attgtcagca acggacaagc atacggcacg ggcaaacttg
    11521 tctgttgata ccgtcacttc atatccgcct tcaatggaac ggacttcggt ctgcaaatcc
    11581 actttcggat aattcatatt cttctgcttg tccagacagt agttgttatg gtacaccctg
    11641 cccgatttgt ccgtatagtc tacgcggaca tataccgttc ctctatctgc cccctccagc
    11701 agcttggcaa gcggtgcgga aaaacagaca cggctgtcat taccggaaat gccgacagat
    11761 ttgtcccagt gataaaccac agtgccgtcg aaccggcaga cctggagctg cagccggccg
    11821 gaagtattct ccaagcggtc ggacactgca tatactttca aatcatcccc ctccactacc
    11881 ggagaaatca ggatgtcatc atagaccttg cgagtataat agtgctgcgc cttccagcgt
    11941 ccgtaatagt cacggctcgc ccaggaagct acgggccaac agtcgttgtg ctgccagaaa
    12001 agcgtcccca tattatacgg catctggcgg cggtgcgact cgatggccgt cttgatggca
    12061 tctccctgca gcacatggtt catataaagg aatgcccgga aatcacgcgg ctttttatat
    12121 tcattcaata ggtaagtctc aatcagcccg ttggcatggt cgccaccacg ctgatgggac
    12181 atcatcacct cggaacgtat atcccagtct tcggggtaag gagcatagcg cttgacggag
    12241 tcgaactctg gaaaagactg aaagccgtac tcgctgaaaa agcgggattt ctcgctgtca
    12301 taatcggaaa tgggtgcttt accatgccag acactccaat agtgacggtc cccgtcagta
    12361 gtaccggaca tctctccctc gaatgcgaac ggagaagaag gccaatagaa ggttccgggt
    12421 gcatactccc tgaccacccc gggtaaggtg acatgatact gctgccggta ctgtgcccaa
    12481 atcttgtcgg catattcctt gttctgccgt tctatctcgc acttccagcc ccagcccagc
    12541 caggcatcct ggcattcatt gtttccacac cacaaagcaa tgcaggcatg attgcgcaaa
    12601 cgtttcacat tgtccaccgc ctcctgatgg atattatcga gcagggcgcc ttctgccgga
    12661 tacatgctgc aggcaaacat aaagtcctgc caaatcataa ttccatgctc atcacacaaa
    12721 tcatagaaga catcgttctc atagatacct ccgccccaga cacgcaacat attcatgttt
    12781 acaccggcgg catcgagaat cgtcctttta taattctcgg gagtgacgcg cggcaggaag
    12841 ttatccgaag ggatgtaatt ggctcctttg gcaaaaaccg gacgcccgtt cagctctata
    12901 tagaaagtat gcccgtcctt atccggctga tgcaccacct tcaaagagcg tatgcccacc
    12961 ctttcggttt tagagtccaa caattccccg cctgcaatga tatccgtacg gaaacggtaa
    13021 aggaaaggct cccccagtcc attactccac cacagcttcg gcttgtgaag gacgaaatca
    13081 acggtcaccc gattggtgcc tcgcttcaaa tccgcttgcc actcgccaag cactcttccg
    13141 gtagcctcgt ctgttatcgt gaccagcact ccgtccatat ccttatcggc atccagctcc
    13201 acatgtccgg caatcacggc cctgcctgca ccgacttcct tctgctcgat aaacacatcg
    13261 ttgattctca aatcgctcca agccctgata tacaccggac gccagatgcc ggaggtaacc
    13321 agacgtgggc cccagtccca gccataatga taacccgcct tacgggcaaa aatgcttatc
    13381 ttcttgttga acaagcctcc gttttcagac tggtcattgg atgccggata ctggtaagga
    13441 agtgcatccc atttggggac gtctatcttt accggcgaat ggaagtacac cttcaatata
    13501 ttattctcct ccctgatgta ctgcctaacg gggatagacc agcggcgaaa catattgtcc
    13561 gcttt
//
