LOCUS       c00057_gnlPro..        10322 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CJGPPNMC_57.
ACCESSION   c00057_gnlPro..
VERSION     c00057_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 22:22:28
            Original ID  :: gnl|Prokka|CJGPPNMC_57
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10322
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10322
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1740:7822]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1741..7822
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..10322
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10322
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..1679
                     /locus_tag="ctg57_1"
                     /transl_table=11
                     /translation="ENTDIEHNFEFGRPVCFFRQSADGKITYMNFTATVSYADETRMVA
                     IMPGAGAVMEVQETDNLGVQLYFDETSYRTMFEALEDTLRSKGNRLAELRDILLGTSKA
                     GFRELYPVRFPWLNSTQETAVNKVLCARDVAIVHGPPGTGKTTTLVEAIYETLHREPQV
                     LVCAQSNTAVDWISEKLVDRGVNVLRIGNPTRVNDKMLSFTYERRFENHPLYPELWSIR
                     KNLRELGSRARRGSYDEREGVRSRMSRLRDRATALEIQINSELFDGAHVIASTLVSSNH
                     RLLNGRRFGTLFIDEAAQALEAACWIAIRKADRVVLAGDHCQLPPTIKCYEAARGGLER
                     TLMEKVVSNKPAVVSLLKVQYRMHEEIMKFPSQWFYNGELEAASEVRYRGILDWDTPIH
                     WIDTSEMDFKEEFVGETFGRINKAEADLLLSELKIYINRISGNRILEEKIDFGIISPYK
                     AQVQYLRNKIKADASLKPYRSLFTVNTVDGFQGQERDVIFISLVRANEEGQIGFLNDLR
                     RMNVAITRARMKLVILGEAETLKHHGFYRKLLEFIQNIGNQ"
     CDS             complement(1741..2784)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_2"
                     /sec_met_domain="IlvN (E-value: 3.1e-47, bitscore: 149.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.8e-41, bitscore: 130.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACQKGTIIMCLLSDAAVMS
                     VWPTIKPYLTPGKALYFSHGFAITWNDRTGVVPPKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAVYQDATGKAFDKTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVQKLYASVKSGNEAQISIDSNSKPDYREKLNAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(2835..3587)
                     /locus_tag="ctg57_3"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYVAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVMFTEK"
     CDS             complement(3584..4144)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_4"
                     /sec_met_domain="ALS_ss_C (E-value: 4.8e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             complement(4177..5928)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.8e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRQAAELI
                     NGAERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTDHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             complement(6020..7822)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_6"
                     /sec_met_domain="ILVD_EDD (E-value: 4.4e-219, bitscore:
                     717.3, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHQLRSSFSTQGRRMAGARALWTANGMKKEQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQFVKEEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVGDKEVAQIEQHACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRKRLFEDAAKLIVANAFRYYEEGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGADFKMDDIDMLSRKTPCLCKVAPNTQKYHVQDVNRAGGIIAIMDELAKGG
                     LVDTNVRRVDGMTLAEAIDRYSITSSNVCKEAIKKYSSAAAGKFNLVLGSQNASYKELD
                     TDRATGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDA
                     ACDGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARPMTPVTRNRE
                     VSKALKAYASMVSSADKGAVRLID"
     CDS             8313..8885
                     /locus_tag="ctg57_7"
                     /transl_table=11
                     /translation="METVENKYITVAYKLYSIENGEKDFEEEAPVEHPFQFISGLGMTL
                     EPFEAQIKDLQIGDKFDFTIPASEAYGEYDDDHVIDLPKEIFMIEGEFDSDRVVEGAVI
                     PLMTSEGQRINGSVVEVKEDIVVMDMNHPLAGCDLNFTGEVVESRLATNEELAEVARMM
                     GGGCGSCGCGDCGDGCGDHECGGGCCH"
     CDS             complement(8985..10265)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_alpha"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg57_8"
                     /sec_met_domain="SDH_alpha (E-value: 1.4e-62, bitscore:
                     200.7, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKTERQQIIDLVKSEVVPAIGCTEPIAVALCVAKAAEVLGRHPE
                     KITVLLSANILKNAMGVGIPGTGMIGLPIAVALGALIGKSEYQLEVLKDCNPDAVEEGR
                     RFIDEKRIHIALKDGIKEKLYVEVCCEVGDEKSTAIIAGGHTSFVYMARNGEVLLNKQA
                     VASTEKEEGALDLSLRKVYDFALTAPLDEIRFILETARLNKAAAESSFEGDYGHGLGKI
                     LRGTYEHKVMGDSVFSHILSYTSGACDARMAGAMIPVMSNSGSGNQGISATLPVLIYAE
                     ENGKSEEELIRALMLSHLTVIYIKQSLGRLSALCGCVVAATGSSCGITWLMGGTYEQVA
                     YAVQNMIANLTGMICDGAKPSCALKVTTGVSTAVLSAIMAMENRCVTSVEGIIDEDVDQ
                     SIRNLTKIGSKGMNETDKLVLEIMTSK"
ORIGIN
        1 cagaaaatac cgatatagaa cataattttg agttcggccg tcccgtatgt tttttccgcc
       61 agtctgccga tggaaaaata acctatatga acttcaccgc taccgtaagc tatgccgacg
      121 agacacggat ggtagcgata atgcccggag ccggtgccgt tatggaagtg caggaaacgg
      181 acaacctcgg cgtgcaactt tatttcgacg aaacatccta tcggaccatg ttcgaagcct
      241 tggaagatac gttacgctcc aaaggcaacc gcctggccga attgcgggac atattgctgg
      301 gaacctcgaa agccggtttc cgagagctct accccgtacg gtttccctgg ctgaactcca
      361 cgcaggagac agctgtaaac aaagtgctgt gtgcccgcga cgtggccatt gtacatggtc
      421 ctccgggaac cggaaaaacg accaccttag tggaagccat ctatgaaacc ctgcatcggg
      481 aaccgcaggt actggtatgt gcccaaagca atactgccgt cgactggatt tcggaaaaac
      541 ttgtggaccg tggcgtcaat gtcctgcgta tcggcaatcc gacccgtgtc aacgacaaga
      601 tgctttcctt tacctacgag cgtcgtttcg agaaccatcc gctttatccg gaactgtgga
      661 gcatccggaa aaatctccgt gaactgggca gccgtgcccg ccgtggcagc tatgacgaac
      721 gcgaaggagt acgcagccgt atgagccgcc tgcgcgaccg cgccaccgca ttggaaatac
      781 aaatcaattc agagcttttt gatggggcac atgtcatagc ctccacgctg gtaagcagca
      841 atcaccggct actgaacgga cgccgtttcg gcaccctttt cattgatgaa gcagcccagg
      901 ccttagaggc tgcctgctgg atagctatcc gaaaagcaga ccgcgtggta ttggcgggtg
      961 accactgcca acttccgccc accataaaat gctacgaagc cgcccgtgga ggtctggaac
     1021 gaacattgat ggagaaagtg gtgtccaaca aacctgccgt tgtctctttg ctgaaagtac
     1081 aataccgcat gcacgaggaa atcatgaaat ttccttccca atggttttat aatggcgagt
     1141 tggaagccgc ttccgaagtg cgttaccggg gcatcctgga ctgggatacc cccatccact
     1201 ggattgacac ctccgaaatg gatttcaaag aagaatttgt gggagagact ttcgggcgca
     1261 ttaataaggc ggaagcggac ctgctcctat cagaactgaa aatctacatc aaccgtatca
     1321 gtggcaaccg cattctggaa gaaaaaatag acttcggcat catctcccct tacaaggcac
     1381 aagtgcaata tctccgcaac aagataaagg cagacgcttc actcaagcct tatcgcagct
     1441 tgttcactgt aaatacggtg gatggcttcc aagggcaaga gcgcgatgtt atcttcatca
     1501 gccttgtccg tgccaacgaa gaagggcaga taggattcct gaatgattta aggagaatga
     1561 atgtagccat cacccgggca cgtatgaagc tggtgatatt gggagaggca gagacgctga
     1621 aacatcacgg tttttaccgg aagctattgg agtttattca aaatataggg aatcaataat
     1681 aaagaaatac cccctccggt aacaccgaag agggtatttc acctatttat ataaagctga
     1741 ttaattgttt tccggacgaa gtttacgaac tgtaacagct gtctgccaca tttcgctttc
     1801 acgcaaggct ttcaattctg cattcagctt ctcacgataa tcgggtttgg agttactgtc
     1861 gatagaaatc tgagcttcgt tacccgactt cacacttgca tacaatttct gtacaaccgg
     1921 cttgatggca tcatggaacg gggtcatcca atccagcgca ccacgctgtg ccgtagtaga
     1981 acagttggca tacatccagt ccataccatt cttggcaaac aatggcatca aagattgagt
     2041 caactcttcc actgtttcat tgaatgcttc agaaggagta tggccgtttt cgcgcaatac
     2101 ctcatactga gccaacagta atccctggat agcacccatc aaggaaccac gttcaccggt
     2161 caagtcggaa gtggcttcac ggatgaaagt tgtctcgaac aaatatcccg aaccgatgcc
     2221 gatacccagt gcaatcgtct tgtcaaaagc cttacccgta gcatcctgat agacggcata
     2281 tgatgagttc aagccacgac cctcgaggaa catggtacga agtgaagtac cggaaccttt
     2341 gggagcaacc ataataacat caatatcttt aggaggaacc acgccggtac ggtcgttcca
     2401 ggtaatagca aaaccatgag agaagtaaag agcctttccg ggagtcaaat aaggtttgat
     2461 agtcggccat acagacatta cagctgcgtc agacaacaga cacatgatga tagtaccttt
     2521 ctgacaagcc tcttcgatgc cgaacaaagt ctcacccggt acccatccgt cagccacagc
     2581 cttttcgtat gtcttgcccg gacgttgtcc tacaatcaca ttgaaaccgt tatcacgcaa
     2641 gttgcaagcc tggcccgggc cttgtacgcc ataaccgatt actgcaattg tttcatcttt
     2701 caaaatctca cgtgcttttt ccaaaggaaa ttcttcgcgg gtcattacat tctcaataac
     2761 accgccaaaa ttcaattgtg ccattttttg ttttaatttt tatttgtggc ttacgccaac
     2821 gttgataaat ttatttattt ctctgtaaac atcactttag agcgacagac cacttcgctg
     2881 ccattctttt tcacctccac atcgtaaacg ccctcaccgg catcatccat gaacaaagtc
     2941 aactcatccc cataatagct ttcggctaca tatgccattt caaaacgacg gatgcgcttc
     3001 tccttataca tctctatcgg gaacaaatca aggatatgct caatgtaacg gatgctgttc
     3061 acatgcccgt taatgtcaat atcactgtat ttggctacca aagcagcaac cggttccttt
     3121 gaggccacct ttatccgcga aggtttttct atcgggcaag gctcatcgca aacataatct
     3181 acaatgctgc cactatgaag agccagcaaa tctgccggct tacgggtatt catgctaatc
     3241 atcgcccaaa cggaacgtgc atacccaatc ttcttgccct ccttatcgat gatagcgaaa
     3301 ttacggtctg taaaaaggcg atagacattc tccacccaag tctgaatgga gaaatcttcg
     3361 tactgataag gcatttcatc cagttcgaca gccagacggg acaataccca agtataattg
     3421 tcctcgttta gagtcgcgat gccaaaaccg cggtcgctgg catggaaacc cgcacaattc
     3481 aacaaatggt tgcccaatac tcccattgtc agccgtccgg taaagtcgac atgaaacggt
     3541 tcggcaacaa acttgtaggt acctatttta ttgttctcgc tcatcatgat tcctggtgtt
     3601 tactttgacg atattttgct tcacggtccg ccagatattc attgacacgc tcaaagcagc
     3661 tggtcgtaat ggctacgcga cccgaacgga cgaactgaag tacgcaatcc aactggcgca
     3721 actcctcata aagattggtt atttcctcac tcatgccatt cttctcaaca atggcaaata
     3781 cagcattcac ctccacaata cgggcattgt acttacggat tactttggac acctccggtt
     3841 tttcttccag cgtaggggtc gttattttat aaagggcaat ctcgtgctga tagatttcat
     3901 catccgtgaa ataatgggct tgcagcacat ctattttctt ggtaatctgc ttggtcacct
     3961 tttcaatggt atccttatcc gtccaagcgg taatggtata tttatgtacc cccttgatgg
     4021 aggaggccga tacattcaag ctctcgatgt ttatctgccg gcgggtaaac acagccgtca
     4081 cctgattcag caaaccggca aagttttccg aatgaacaat gattgtatat agttttttat
     4141 ccatagatag agtaaattct ttaatttcgc atgacttcag cattccaaca acatctgatt
     4201 gaccgaaccg cccggaggtg tcatcggcat tacatttcct tcttcctcca cacaagcttc
     4261 gagcaggaat ggtccgtcag tcgctatcat ctcgtcaatc gcttttgcca gctcctcgcg
     4321 ggtcattacc ctgcgtgcag gaatatcata tgccgaagca atcttcatat aatccggatt
     4381 catcatcgga gtaaacgaat aacgacgatt gaagaacatc gcctgccatt gacgaacatt
     4441 gcccaggaag ttattgttca acagaatcat cttcaccgga gccttttgtt ccatgatggt
     4501 acccagttcc tgcaggttca tctgcaagcc gccgtctccc atgaatacgc ataccgtgcg
     4561 gtccggacgt ccaaaagtgg caccgatagc tgccggaagg ccgaagccca tagtacccag
     4621 gccaccggaa gtaacaatgc tacgttcctt gctgtatttg aaataacggg cggacatcat
     4681 ctgattctgg ccgacatcag tcaccaatat cgcctcgtta tgggtagcct cactcacagc
     4741 acgcaccacc tcacccatgc ttagcgcttt tcctgccgga tgtaattccg gacggattac
     4801 cttttcctct tccacttcct cgtattgccg gaaactgtca atccattcct gatggttggc
     4861 gggttccagc aattgggtaa cggcagccag tgtctctttg caatctccca ggacagcaac
     4921 atcagtcttt acattcttat ctatttcggc agggtcaata tcaaagtgga taatcttcgc
     4981 ctgcttggca tatgtttcca atttacccgt cacacggtca tcaaagcgca tgcctacggc
     5041 gataaggaca tcacatttat tggtattgat attgggcccc aggttaccgt gcataccaag
     5101 cattcctttg ttcaacggat ggtccgtagg caatgcggaa agtcccaata aagtgcatcc
     5161 ggcaggcatt ccggctttct caatgaaagc acgaagctct tgctgggctt ctcccagctc
     5221 cacgccttgt cctaccagca ccaaaggccg ttccgcacca tttattaatt cagcagcctg
     5281 ccgtatggcc tccggctcca tttcgggaac tggaagatag ctacggacat agtccacctt
     5341 agtaggcgca tattctgttt tctccacttg ggcgttttta gcaaaatcca gcacgaccgg
     5401 tcccggacgt ccgctctttg ccacatagaa agcacgtgcc actgcccagg ccacatcttc
     5461 tgcacgacga atctggtaac tccatttcgt gataggctga gtaatgccta ccaagtccac
     5521 ttcttgaaat gcatccgtac ccaagaagtt cgtccctacc tggccggcaa tgacaacgat
     5581 aggcgtactg tcaatcatgg catctgcaat gcccgtgata gtattggtag cacccggtcc
     5641 actggtaacc agacaaacgc caacctcgcc tgatacacgt gcaaagcctt gtgccgcatg
     5701 ggttgctcct tgttcatggc gaaccaagat gtggttcaat tccttccggt ggtcgtataa
     5761 ggcatcgaat accggcatga tgctccctcc cggataaccg aaaatagtct ttactccctg
     5821 atgctccaga gagcgcatca atgcttctgc gcctgttatt agagcctcac cccgaccctc
     5881 tccttgggag agggaggaaa agttactctt tttattatta tcagccatac tttatctatt
     5941 cattatattt aaaagctcaa tagtagcttg aaaaatttgt ttcattctct cctcccctcg
     6001 ctttcggaaa ggggggcttt taatcaatca gcctcacagc ccctttgtca gcggaactca
     6061 ccatactggc atatgctttc aatgctttgg agacttcacg gttgcgggtt accggagtca
     6121 tagggcgtgc tgcaagctct tcatccgtca acttcacatt gatagaacgg ttcggtatat
     6181 caatttcgat aatgtcccca tccttaatct tgccgatatt accaccggca gccgcttcgg
     6241 gagaaacatg tccgatactt agtccggaag taccaccact gaaacgcccg tcggtaatca
     6301 atgcacactc cttacccaga tggcgggatt tgatataaga agtaggataa agcatctctt
     6361 gcatacccgg tccacctttc ggcccttcgt gagtgatgac gacgacgtct ccactgacca
     6421 cctttccacc cagaataccg tcacaagccg catcttgtga gtcgaagact ttcgctggcc
     6481 ccgtaaattt ccagatactc tcgtctacac cggcagtctt gacaacgcaa ccgtcctgag
     6541 ctatatttcc cttcaaaacc gccagaccgc catccttgct gtatgcatgt tccaaatcac
     6601 ggatacaacc ggtcgcacgg tccgtatcga gttccttata agacgcattt tgtgagccga
     6661 gtaccagatt gaactttccg gctgccgcac tggagtattt cttgattgcc tctttacata
     6721 cattagagct ggtaatacta taccggtcga ttgcctctgc caacgtcatt ccatccacac
     6781 ggcggacatt cgtatcgacc aatccgccct tggcaagctc atccatgatg gcaatgatgc
     6841 caccggcacg gttaacgtct tgtacatgat acttttgggt attgggagct accttgcata
     6901 agcagggggt cttgcgagag agcatgtcaa tgtcgtccat cttaaaatcc gctccggctt
     6961 cgtgagccac agccaacaaa tgaagtactg tattagtgga accgcccatc gcaatatcca
     7021 gcgtcatggc attcaaaaat gcctcgcgag tagcaatact gcgcgggagt acactctcat
     7081 ccccttcttc ataatatcta aaggcattcg ctacaatcaa cttagctgca tcctcaaaca
     7141 gtctcttgcg attttcgtga gtggctacaa tcgtgccgtt accgggcagt gccaatccaa
     7201 tcgcttcatt caggcaattc atggaattag cggtaaacat gcctgagcag catccgcaag
     7261 tggggcaggc atgttgctca atctgtgcca cctctttatc gcccacactt tcatcagcag
     7321 atttaatcat ggcatcaatc aaatccaaat gctgtccgtt ccattccccg gcttccatcg
     7381 gaccgcctga aacaaacaca gtcggtatat tcagcctcat agccgccatc aacatccccg
     7441 gagtaatctt gtcacagtta ctgatgcaaa ccatagcatc cgccttatgg gcatttacca
     7501 tatactccac actatcggca atgatatctc ttgaaggcag ggaataaagc ataccgtcgt
     7561 gtcccatagc gataccgtcg tcaatggcaa tcgtattgaa ctccgcagca aaacacccca
     7621 gcttttcaat ctcttccttt acaaactggc ctatttcgtg caggtgtaca tgcccgggga
     7681 cgaattgtgt aaatgaattg actatagcga taatgggctt acccatctgt tccttcttca
     7741 taccattcgc cgtccacaat gcacgggctc ccgccatgcg gcgaccttgt gtgctgaacg
     7801 agctgcgtaa ctgatgcttc attttcaaat ctccttttaa tgaaaaagcc tctcccacta
     7861 tagtgagaaa ggcttaataa attatcttct aacgtacgaa tacatacata acctttctca
     7921 cgctcttgat gccaccacca cgacgcgaat aatatgcagg actgccaggt taatagatgt
     7981 atgtaaattc ataacttaat tcttcttttt tgtttcaaac gtgctgcaaa ggtaagggct
     8041 tttttataat ctccaaacaa attgaagaaa aaaataagat aaatatgaat aatcgtaaga
     8101 aaatatcgcc ctaaaatcct attttatcac ttaacagttc taaatagaac cattcagaca
     8161 gccaatgtaa atgtattgcc aatcattgaa accatttaat aatctgaaaa ttaccaaagg
     8221 ctctctacat cccgaaacaa ataattcgta tctttgtctc ttcaaatact caaaaaaaca
     8281 gtatttacta attaaataaa gatagaaaat taatggaaac agtagaaaac aagtacatca
     8341 ccgtagcata taagctgtac tcaatcgaaa acggagaaaa agatttcgaa gaagaagcac
     8401 ccgtagagca tccttttcag tttatctcag gtctgggaat gacactcgaa ccctttgaag
     8461 cccagataaa agacttgcaa ataggcgata aattcgactt taccattccg gcatcagaag
     8521 cttatggtga atatgacgac gaccatgtta ttgacctccc caaagaaatc ttcatgatag
     8581 aaggagaatt cgacagcgat cgtgtagtag aaggtgccgt tatccccttg atgacttctg
     8641 aaggtcaacg catcaacgga agtgtggtag aagtgaagga agatatcgtc gtaatggata
     8701 tgaaccatcc gctcgcaggt tgtgacttga acttcactgg agaagtagtg gaaagccgcc
     8761 tggctacaaa cgaagaactt gccgaagtcg cccgtatgat gggtggcggt tgcggcagct
     8821 gcggttgtgg tgactgtggc gacggatgcg gcgaccatga atgtggaggc ggatgctgcc
     8881 actagaagaa ttaaaaatga agaattaaaa atgaaagaat caaactacgc aatataagta
     8941 tgctgcatga taattctttc atttttaatt cttcattttt ttaattattt acttgtcatt
     9001 atctccaata ccaatttatc cgtttcattc attcctttag aaccgatttt tgtcagatta
     9061 cggatactct gatccacatc ctcatcaata ataccttcta cggaagttac acaacggttt
     9121 tccatggcca tgatggctga aagtactgcg gttgaaactc cggtagtcac tttcaatgca
     9181 caactaggtt tggcaccatc acaaatcatt ccggtaagat tggcaatcat gttctgtaca
     9241 gcatatgcca cctgctcata agtacccccc attagccaag ttataccgca actggaacca
     9301 gtggcagcaa ccacacaacc gcataaggcg gataaccgtc ccaaactctg cttgatatag
     9361 attactgtca aatggctcaa catcaaggca cgaatcaatt cttcttctga tttcccgttt
     9421 tcttcggcat aaatcaaaac cggcaacgta gcggatatac cttgattacc gcttcctgaa
     9481 ttactcatga ccggaatcat ggctcctgcc atacgggcat cgcaagcacc ggaagtataa
     9541 gaaagaatat gggaaaaaac actgtccccc ataaccttat gctcgtaagt accacgaagg
     9601 atttttccca agccatgtcc gtaatcaccc tcaaaagagc tttctgcggc agccttattc
     9661 agacgggccg tttcgaggat aaaacgaatt tcgtccaacg gagccgtcaa agcaaaatca
     9721 tagactttcc gcaagcttaa atccagcgca ccttcctcct tttctgtgct tgcaacagcc
     9781 tgcttgttca acagcacttc cccattgcgt gccatgtata caaaggaagt gtgtccacct
     9841 gcaatgatag cagtggactt ttcatccccg acctcacaac aaacttcaac ataaagcttc
     9901 tctttaatgc catctttcag tgctatatgg atgcgctttt catctataaa acgtcttcct
     9961 tcttccacgg catcgggatt acaatccttc aatacctcca gttgatattc cgatttaccg
    10021 attaaggcac caagcgctac tgcaataggc agcccaatca ttcctgtacc gggaattcct
    10081 acgcccatcg cgttcttcaa gatattggca cttaaaagaa ccgttatctt ttccggatgt
    10141 ctgcccaata cttccgcagc ttttgccaca cacaatgcca cagctatagg ttctgtgcaa
    10201 cctatagcag gaacgacctc ggatttaacc aaatcaataa tctgttgtct ttccgttttt
    10261 gtcatattta ttcaatttag atgcagacaa aggtaatgta ttttattcta taatagaagg
    10321 aa
//
