LOCUS       c00300_gnlPro..        14665 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CJGPPNMC_300.
ACCESSION   c00300_gnlPro..
VERSION     c00300_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 22:22:28
            Original ID  :: gnl|Prokka|CJGPPNMC_300
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14665
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14665
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:4665]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..4665
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..14665
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14665
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             2..469
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg300_1"
                     /sec_met_domain="Glyoxalase_4 (E-value: 6.5e-26, bitscore:
                     81.7, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LYTFIKKDTILTLIYIVMKISHIEHLGIAVKSIEEALPYYENVLG
                     LKCYNIETVEDQKVRTAFLKVGDVKIELLEPTSPESTIAKFIEKNNGNGGMHHLAFAVE
                     DGVAGALAEVEEKGIRLIDKAPRKGAEGLNIAFLHPKSTLGVLTELCEKPE"
     CDS             528..2081
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg300_2"
                     /sec_met_domain="CT_Btheta (E-value: 2.8e-291, bitscore:
                     956.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIDRRAAARLGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYIFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGLALIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDNPN
                     KPYDMYEVIGAIIDNGEFLEIQKDYSKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKEQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRIIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             2500..3045
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg300_3"
                     /sec_met_domain="OAD_gamma (E-value: 7.7e-18, bitscore:
                     55.8, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LYDSGKKLLDQVIVPAGTLKANQSYARVSDAADQWEVKGGSEDKY
                     VTPSTNNKTIDSNAKMEKFEEHDSVGIGMAISAMSVVFCGLILLYISFKIIGKISVNLS
                     KRNAMKAKGITDKQEAKEKQLGQAPGEVFAAISMAMHEFQSDVHDVEDTILTITRVKRS
                     YSPWSSKIYTLRETPHKK"
     CDS             3069..3503
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.3; E-value:
                     2.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg300_4"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.2e-21, bitscore:
                     67.3, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNVYKVAIGDIEDNIAHVEVNGTPYKVEMEKAPKVV
                     VKPVARPAATSAPAAPATPVVKPAAASTGKSGVKSPLPGVILDIKVNVGDTVKKGQVII
                     ILEAMKMENNINADKDGKITAINVNKGDSVLEGTDLVIIE"
     CDS             3505..4665
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg300_5"
                     /sec_met_domain="OAD_beta (E-value: 1e-152, bitscore:
                     498.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFITFLGNNLADFWTYTGFANATVGHVVMLLVGLFFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYMIALAIGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRWLTSKNERLIRMKPPRVVSHTEKVMFP
                     IIGLLLTTFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFGLGALSFVIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             4919..6187
                     /locus_tag="ctg300_6"
                     /transl_table=11
                     /translation="MANYDYETALMLIDQETPTVPLLYQKGKALKGLGNNLEALSVFQE
                     VVAQDSLNPRAYIEAAECCKSLAKYSEALDYYQNALHINPDNKYARIQYISLLMNMKRY
                     RESLKESNLLAERDSSAYVLHLRAESMGQVYDNTEIMHVIDAYLDIQKRYPNDYLSAAK
                     LGNIYVAGHQYEDAINITEKYRSIDSTNVLVNRINAQAYCLNKDYPKAIERYEQLLQEK
                     DSSFQTCFYAGISYYALEDFYPAHDLLERALKDDNTNINVLYYLGRACSKTSWKEDGVT
                     YLETAVSLAMPSDSVMSRLYVGLADCYKMAFQYTDQANTLLTQYEKYDRQKHKLLYDAA
                     FIYYYYLKDASKAERYLTAYLKTRPKNSKDKVQEVDADGVPIIGEDNRYNAAENWLKDI
                     REKRKKEDFFKGKVDTASVTPIK"
     CDS             6358..8148
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg300_7"
                     /sec_met_domain="Alpha-amylase (E-value: 2e-63, bitscore:
                     205.7, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVNKIDPPFWYTGMQNPELQLMVYGEGIGNAAVSVNYPGVSLSS
                     TVKLESNNYLLVYLKLDKDVKPGKFNLTFTEGKKKLVKEYELKARNKKGCEHKGFDASD
                     ALYLLMPDRFANGNPDNDQIAGMAEYKIDRNDPNARHGGDLAGIEQHLDYFSNLGVTAL
                     WFTPVLENNMTGGSYHGYATTDYYKVDPRFGTNEEYKQLIEKAHARGIKIVMDMIFNHC
                     GVEHVWIKDMPSKDWFNNPDHENNFVQTSFKLTPHVDPYTSQYDADQMNDGWFVPSMPD
                     LNQKNPHVYRYLVQNSFWWIEFANIDGIRMDTYPYADYDAMSNWMKELSEEYPNYNTVG
                     ETWVTEPAYTAWWQKDSKLSAPKNSNLKTVMDFSFFDKINTAKNEQTETWFKGLDRIYN
                     NFVYDFLYPNPASVLAFIENHDTDRFLGEGNNLPMLKQASTLLLTTRRIPQLYYGTEVM
                     MNGVKSKSDGYVRKDFPGGWTGDATNALTPAGRTKIQNECYDFYKTILNWRKGNDVIAK
                     GSMVQFMVQNGVYAYARQYEGKTIFVMLNGTDAETTVPLKFYKEILKDSKQGKDILSGK
                     AITFGEELKMGPRESLVIEL"
     CDS             complement(8619..9629)
                     /locus_tag="ctg300_8"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVDYAHQFDVTVEGELGVLAGVEDEVSAEHHT
                     YTNPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEQCHVDPATGRLVPPPLEFAVLDAV
                     MEKLPGFPIVLHGSSSVPQEEVDTINKYGGKLEAAIGIPEEQLRKAAKSAVCKINIDSD
                     SRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSENKLAQLD"
     CDS             complement(9912..10919)
                     /locus_tag="ctg300_9"
                     /transl_table=11
                     /translation="MRKLLVLCSFWLCVATLGAQNAERKLYSVAFYNLENLFDTIHDAG
                     KNDYEFLPNGSYQWTAKKYESKLQNLSKVLGSLSRDLVPEGPAFIGVAEAENSRVLEDL
                     VKQPAISNYEFVHYEGPDRRGIDCALLYDPKQFSVTHSKLVLSTPFEGDTVHLTRGFLI
                     VDGQLAGERVCVIVNHWPSRGAKSPVRVHAARQVKALKDSLMRSDKKLKLIVMGDMNDD
                     PMDESMEVLGARKYPKQVKKGEFYNPWWVTLEDKGVGTLLYRGKWNLFDQIVISKPLLK
                     AKKGLRYDHNEVFIRDYLIQQDGKYKGSPLRTHGGRTWLNGYSDHLPTIIYLKN"
     CDS             11108..11359
                     /locus_tag="ctg300_10"
                     /transl_table=11
                     /translation="MKKGIHPENYRPVVFKDMSNGDVFLSRSTCNTKETIEFEGETYPL
                     VKLEISSTSHPFYTGKSKLVDTAGRVDKFMSRYGNRKK"
     CDS             complement(11615..11995)
                     /locus_tag="ctg300_11"
                     /transl_table=11
                     /translation="LYVRGYVVVLIGYLVQFIEIVQAFFVDFLAQFVLVTAVVEIFVKM
                     ILQVYLLPEFPVRFRSGYGNDTHLIRRNGFLYAIHFDGIVNVIAVFTGIVHFDNPADND
                     RGTGGRLLVLFCQFSFDGDVSA"
     CDS             12110..13060
                     /locus_tag="ctg300_12"
                     /transl_table=11
                     /translation="MVISTGLLCTLDSEDELAAVIACELGHFVLDHQVNNIYRAERRAK
                     RAAFWADVFATTASAALDVAYWDDNEDAYAVSLVADIGAIASLLSIPATDRLGMKYKTS
                     QEISSDRLARQLLAFKGYNPDGIASALGKIIGYYNLHQRNKDIPRYGSIGNLQKRIEKA
                     GESHSLSARPYLRTTSDVVSFNASMNYANKRYKETARLIRKNIDNRLATDNDYIILVKA
                     EMALSNTEEVNNRCLAMLDKAQEMAGTSPNLDIYKQKILLLMRMNKQAQAADILKEYIT
                     LLSAYEGQGIEGTEKEWTNKEIGWANQMLDRISRI"
     CDS             complement(13151..14239)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GCV_T"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GCV_T_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg300_13"
                     /sec_met_domain="GCV_T (E-value: 5.4e-97, bitscore: 314.9,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 1.2e-24, bitscore: 76.9,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTTPFTEKHISLGAKMHEFAGYNMPIEYSGIIDEHLTVCQGVGV
                     FDVSHMGEFWVKGPHALDFLQKVTSNNIAALTPGKVQYTCFPNENGGIVDDLLVYHYEP
                     EKYLLVVNASNIEKDWNWCVSHNTEGAELENASEHMAQLAVQGPKAIQALQKLTSINLS
                     DLPYYTFTHGEFAGEKDVIISNTGYTGAGGFELYFYPEAAMKIWDAVFEAGAEFGIKPV
                     GLGARDTLRLEMGFCLYGNDLDDTTSPIEAGLGWITKFVEGKNFTNRPMLEKQKAEGTT
                     RKLVGFEMIDRGIPRHGYELYSTDGIAIGVVTSGTMSPTRKIGIGMGYIRPEYSKVGTE
                     ICIDMRGRKLKAVVVKPPFRKQ"
ORIGIN
        1 gctttatacc tttattaaaa aggatacaat actaacatta atttatatag ttatgaagat
       61 ttcacacatt gagcatctgg gcattgccgt taagagcatt gaagaagccc ttccgtacta
      121 cgaaaacgtt ttaggtttga aatgctacaa catcgaaacc gtggaagatc agaaagttag
      181 aaccgctttc ctgaaagtgg gcgatgtaaa gatcgaattg ttggaaccta cttctcccga
      241 aagcacaatt gccaagttca tcgaaaagaa caacggtaac ggtggcatgc atcatctggc
      301 atttgccgtt gaagacggag tggccggtgc gcttgccgaa gtcgaagaaa aaggtatccg
      361 ccttatagac aaagctcccc gcaaaggtgc agaaggtctg aacattgcat tcctgcatcc
      421 gaagtcaact ctcggtgtcc tgaccgagct ttgcgagaaa ccggaataag caagactgta
      481 aaatcatcaa atcataaatt gtataaacac ttaaagaata taaattcatg agtaatcaac
      541 ttgaaaagat taaagagctt atagaccgcc gcgctgcagc acgtctcggt ggtggtgaaa
      601 aagcgattgc aaagcaacac gagaagggta aatatacagc tcgcgagcgc atagccatgc
      661 ttctcgacga aggcagtttc gaagaaatgg acatgttcgt agaacataga tgcaccaact
      721 tcggcatgga aaagaaacac taccccggtg acggtgtagt aaccggttgc ggtacaatcg
      781 aaggccgtct ggtttatatc ttcgcacagg acttcacagt ttctgccggt tcactgtccg
      841 aaaccatgtc tctgaaaatc tgtaagatta tggaccaagc catgaaaatg ggtgctccgt
      901 gtatcggtat caacgactcg ggcggtgcac gtattcagga aggtattaat gccttggctg
      961 gctacgctga aatcttccaa cgtaacatac ttgcttcggg tgtcattccg cagatttccg
     1021 gtattttcgg tccttgtgcc ggtggcgccg tttactctcc tgccttgaca gactttactt
     1081 tgatgatgga aggtacatcc tacatgttcc ttaccggtcc gaaggtagta aagactgtaa
     1141 ccggagaaga cgtaagccag gaaaacctgg gtggcgcgag cgttcactcc accaaatctg
     1201 gtgttactca ttttactgca cagacagaag aagaaggttt ggctcttatc cgcaaactgt
     1261 tgagctacat tccccagaac aacctggaag aagctcccta tgtagactgt acagacccta
     1321 tcgaccgtct ggaagattcc ctgaacgaca tcattcctga taacccgaac aagccgtacg
     1381 atatgtacga ggtaattggt gctatcatag ataatggtga gttcctcgaa atccaaaaag
     1441 attattcaaa gaatatcatt attggtttcg cacgtttcaa cggacagtcc gtaggtattg
     1501 ttgccaacca gccgaagtat ctggcaggtg tgctcgacag caacgcatcc cgcaagggcg
     1561 cacgcttcgt ccgtttctgc gacgccttca atattcctat cgtatcattg gtagacgtac
     1621 cgggattcct tccgggaacc ggccaggagt acaacggcgt catcctgcac ggtgccaaac
     1681 tgctgtatgc atacggtgaa gctactgtac ccaaggttac catcacactg cgtaaatcct
     1741 acggtggttc gcacatcgtg atgagctgta agcagctgcg tggcgacatg aattatgctt
     1801 ggcctactgc tgaaatcgct gtaatgggtg gtgcaggtgc tgtagaagta ttatatgccc
     1861 gcgaagccaa agagcaggaa aatccggctc aattcctggc tgaaaaagag gctgaataca
     1921 ccaagttgtt tgccaatcct tataatgcag ctaaatatgg ctacattgat gatgttatcg
     1981 aaccgcgtaa cacacgtttc cgcatcattc gtgccctgca acagttgcaa accaagaaat
     2041 tgactaaccc ggctaagaag catggtaata ttcccttgta atcaagcttt tcacactaaa
     2101 acaagaacga ttatgaataa aacaaaaatc ggaatattcc tttcattgat gctggtgtta
     2161 ggcttttgct cttcttgcaa agaacagaaa tcgaacaaca aactgctgct gaatgaagtg
     2221 ctggtcaaca acgaaagcaa ctatcaggat gactacggtg tgcacagcgc atggattgaa
     2281 atattcaaca gatcatacgg cagcgccgac cttgcaggtt gctatctgaa attcagcagc
     2341 cagccgggtg atactgccag ttatttcatt cccaaaggtg acgttctgac actcataaaa
     2401 ccacgtcagc atgcactttt ctgggctgat ggagaaccaa gacgcggtac atttcatacg
     2461 aacttcaaac tggatgccac aaatgccaac tggattgggt tgtatgattc cggcaagaaa
     2521 ttgcttgatc aagtcatagt gcctgccggt actttaaaag ccaaccaatc ctatgcccgt
     2581 gtcagtgatg cagccgacca atgggaagta aagggtggaa gcgaagataa atatgtcact
     2641 ccgagtacca acaacaagac tatcgacagc aatgccaaaa tggaaaaatt cgaagagcat
     2701 gacagcgtag gtatcggtat ggctatttct gccatgagcg ttgtattctg cgggctgata
     2761 ttactctaca tctccttcaa gattataggt aaaatatcag ttaacctcag caaacgcaat
     2821 gccatgaaag ctaaaggtat tactgataaa caagaagcaa aagagaaaca actggggcag
     2881 gctccgggag aagtttttgc tgccatttca atggccatgc acgaattcca aagcgatgta
     2941 cacgatgtgg aagacacgat acttaccatt acccgtgtaa aacgcagtta ctcaccgtgg
     3001 agttcaaaga tttatacgtt gcgtgagact cctcacaaaa agtaagtcac ccataataaa
     3061 ataaaacgat gaaagaatat aaatataaaa ttaacggtaa cgtatataaa gttgccattg
     3121 gagatattga agacaacatc gctcatgtag aagtgaacgg tactccctac aaagttgaaa
     3181 tggaaaaagc accgaaggta gttgttaaac cggtagcacg tccggcagcc acatccgctc
     3241 ctgctgctcc tgctactccg gtagtaaaac cggccgctgc ttctaccggc aagtcaggtg
     3301 taaaatctcc gcttcccggt gtaatcctcg atatcaaagt aaatgtcggc gatacagtaa
     3361 agaagggaca agttatcatc attttggaag ccatgaagat ggaaaacaat atcaatgctg
     3421 ataaagacgg taagattaca gccatcaatg taaacaaagg ggactctgtt ctcgaaggta
     3481 ctgacctcgt aattattgaa taatatggga gaatttatca catttttagg aaacaacctt
     3541 gccgacttct ggacttatac aggttttgcc aatgcaacgg taggacatgt ggtaatgctt
     3601 ctggtaggtt tgtttttcat atacttggct gtagccaagg aatttgagcc gatgctatta
     3661 attcctatcg gtttcggtat gctgattggt aatatacctt tcaatatgga agccggatta
     3721 aaagtcggta tctatgaaga aggttccgta cttaatattc tgtaccaggg agtaacctcc
     3781 ggttggtacc cgccactcat attcctgggt atcggtgcca tgacggattt ctctgctttg
     3841 atatcgaacc ccaaattaat gttggttggt gcagcagccc aattcggtat attcggtgct
     3901 tatatgattg cccttgccat aggatttgac ccgatgcagg ctggtgcaat cggtatcatt
     3961 ggtggtgccg atggtccgac tgccatcttc ctctcttcca aactggctcc taacttaatg
     4021 ggtgccattg cggtatcagc ctattcatat atggcattag taccggtgat acagccgcct
     4081 attatgcgtt ggctgaccag taaaaatgaa cgtcttatcc gtatgaaacc tccccgtgtg
     4141 gtttcacata cggaaaaagt aatgttcccg attatcggtt tgttactaac cacattcctt
     4201 gtaccatccg gtctgccttt gctgggtatg ctgttcttcg gtaatttact gaaagaaagt
     4261 ggagttacac gtcgtctggc aaacacagcc agtggtccgc tgattgatac cattactatt
     4321 ctgcttggtt tgacagtagg tgcttctacg caagcatccg agttcttaac ccttgattca
     4381 atcaagatat tcggtctggg cgccttatca tttgtcattg ccacagcatc cggtgtcatc
     4441 ttcgtgaaga ttttcaacct cttcctgaag aaaggcaaca agattaatcc gttgatcggt
     4501 aatgccggtg tatctgccgt acccgactct gcacgtatct cccaagtagt aggtctggaa
     4561 tacgatccta ccaactatct gctgatgcat gccatgggcc cgaacgttgc cggtgtaatc
     4621 ggttccgctg tagcagcagg tatcctgctg ggattcttaa tgtaatacat ttattcattc
     4681 cgttatccgg cttgaattct gaactatttt agagcccctt catttttgga ggggcttttt
     4741 cgttaatcta tctaaaacag attacgatta tttcgtaaat acattctttt tagtaacttg
     4801 cagtcagttt aacctcatat aaatgatata ctgtatgcga aagcttttta tctccttatg
     4861 tttcagtgca tgctgttcgc ttctggcggc acagaccaca aatcccattc aagaggcgat
     4921 ggccaactac gattatgaaa cagccttgat gctgatcgat caagaaaccc cgaccgtccc
     4981 cctactctac caaaaaggga aagcgctgaa agggctgggc aataaccttg aagctctgag
     5041 cgtatttcag gaagtcgtag ctcaggattc tctcaatccc cgggcataca ttgaagctgc
     5101 cgaatgctgc aaatcacttg ccaaatatag cgaggcactg gattactacc aaaatgcgct
     5161 ccacataaat ccggacaata aatacgcacg catccagtat atcagtctgc tgatgaacat
     5221 gaagagatac cgtgagtctc taaaggaaag caacctgctg gcagaaaggg acagttccgc
     5281 ctatgtacta caccttagag ccgaaagtat ggggcaagtc tatgacaaca cagaaatcat
     5341 gcatgtgata gatgcctacc tggacataca gaaaagatat cccaatgatt acctgtctgc
     5401 tgccaaactc ggcaacatct atgtagcagg ccaccagtat gaagacgcca taaacataac
     5461 ggagaaatac cgttccatag actccaccaa cgtccttgtg aaccgcatca atgcccaagc
     5521 ctattgcctg aacaaagatt accccaaagc aatagaaaga tatgaacaac tgttacagga
     5581 aaaagacagt tctttccaaa cctgcttcta cgccggaatc agctattatg ccctcgaaga
     5641 cttctaccca gcacacgacc tgctggaaag ggctcttaaa gatgacaata ccaacatcaa
     5701 cgttctctat tatctgggac gcgcctgctc caagacatca tggaaagagg atggagtgac
     5761 ttatctggaa actgccgtaa gcctcgccat gcccagcgac agtgtcatgt cccgcctata
     5821 tgtggggctt gcggactgct acaagatggc atttcaatac accgaccagg cgaataccct
     5881 tctgacgcaa tacgaaaaat acgaccggca gaaacacaaa ctgctctacg acgcagcctt
     5941 tatctattat tactatctga aagatgcgtc caaagcagag agatacctaa cggcctacct
     6001 gaaaacccgt ccgaaaaaca gcaaggacaa agtgcaggaa gtagatgcgg acggagttcc
     6061 catcatcgga gaagacaacc gatacaatgc cgccgaaaac tggctgaagg acatcagaga
     6121 aaagcgcaag aaagaggact tcttcaaggg aaaggtcgat accgccagcg taacccccat
     6181 caaatagccc caatgaaaac gtttgcataa tataataagg tacagtaacg gagaaagatt
     6241 aactttctcc gttatttgtt ttaaattagc gcaaaaatta accgtaaagt tactatcatg
     6301 aaaaaagtat tcttaatctt gggaacactc ttactctccc tcagtacgta tgcagctatg
     6361 aatgtgaaca aaatcgaccc tccgttttgg tacaccggca tgcagaaccc ggaactccag
     6421 ctgatggtct atggcgaagg catcggcaac gcggcagtat ccgtcaatta tcccggcgtc
     6481 tcattgagca gcaccgtcaa gctggaaagc aacaactacc tcctggtcta tctgaaactg
     6541 gacaaggatg taaaacccgg caaattcaac ctcaccttca ctgaaggaaa aaagaaactc
     6601 gtaaaggaat atgaactgaa ggcacgcaac aagaaaggtt gcgaacataa aggtttcgac
     6661 gcctccgacg cactgtacct gctgatgccc gaccgctttg ccaatggcaa cccggacaat
     6721 gaccagattg cgggcatggc cgagtacaag atagaccgca atgaccccaa tgcacgccac
     6781 ggcggtgacc ttgccggcat cgaacaacac ctggactact tctccaacct cggcgtcaca
     6841 gccctctggt ttactccggt actggaaaac aacatgaccg gcggttccta tcacggctat
     6901 gccaccacag actactacaa ggtagacccg cgcttcggta ccaacgaaga atacaagcaa
     6961 ctgattgaaa aagcccatgc acgcggcatc aaaatcgtaa tggacatgat tttcaaccac
     7021 tgcggcgtag agcatgtatg gattaaggac atgccctcca aagattggtt caacaacccc
     7081 gaccacgaaa acaacttcgt gcagacctcc ttcaaactga ccccgcacgt agacccttat
     7141 acttcccagt acgatgccga ccagatgaac gacggctggt ttgtaccttc catgcccgac
     7201 ctcaaccaga agaatcctca cgtttaccgc tacctggtac agaacagttt ctggtggatt
     7261 gaattcgcca acatcgacgg catccgcatg gacacttacc cgtatgccga ctatgatgcc
     7321 atgagcaact ggatgaaaga gctcagcgaa gaatatccca actacaacac cgtgggcgag
     7381 acctgggtta ccgaacccgc ctacaccgcc tggtggcaga aggattccaa gctatcagcc
     7441 cccaagaaca gtaacctcaa gaccgttatg gacttcagct tcttcgacaa gataaacacc
     7501 gccaagaatg aacagaccga aacttggttc aagggactgg accgcatata caataacttc
     7561 gtatacgact tcctctaccc caaccccgct tccgtactgg cattcatcga aaaccacgac
     7621 accgaccgct tcctgggcga aggcaacaac cttccgatgc tgaagcaagc ctctaccctg
     7681 ctgcttacca cccgccgcat tccgcaactc tactacggaa cggaagtcat gatgaatggc
     7741 gtgaagagca agagcgacgg ctatgtccgc aaggacttcc ccggcggatg gaccggtgac
     7801 gcaacaaacg cactgacccc agccggacgt accaaaatac agaacgagtg ctacgacttc
     7861 tacaagacca tcctaaactg gcgcaaagga aacgatgtga ttgccaaagg cagcatggtg
     7921 cagttcatgg tacagaatgg tgtttatgcc tacgcacgcc agtacgaagg caagacgata
     7981 ttcgtgatgc tgaacggtac agatgcagag accaccgttc ctttgaaatt ctacaaggaa
     8041 atcctaaaag acagcaagca gggaaaagat attcttagcg gcaaggccat caccttcggt
     8101 gaagagctga agatgggccc cagagaatca ttagtgatag aattataacg cgcactccac
     8161 acagagagct cattcttgca aatctccctt gcagatagct tgcagacacc tcgcctgcca
     8221 gccatctgca agggattttt agtatggaat aggtgtcacg gggatatgct tttcaccggt
     8281 ctcaaatata gctaatctgt tagttcataa cggtgaacac tttgttccag tatagagaaa
     8341 caaagtgttc ggatatgtag aaacaaagtg ttcttacgta ttggaacgaa gtgtttttgc
     8401 atattggaac gaagtgttct ctttattgaa acaaactgtt cagttaaggg aaacagactg
     8461 ttttgttaaa ggaaacagac tgttgtacac gttgaaacat ccgcttctga aataaccggc
     8521 gaacttaacc atcccacaac accggcctat atataacaag tcagcccttg caacatcaat
     8581 attgcaaggg ctgacgctat attcggatta tctttcgatt agtccagttg agccaatttg
     8641 ttctctgaac caagcacgtt gatgatttta tgcttgtaca gtttttccat attgtcacga
     8701 gccggaccca gatacttacg cgggtcgaat tctgccggtt tttcagcaaa tgtcttgcgg
     8761 atagcagctg tcatagccag acgtgagtca gagtcgatgt tgattttgca aacagcagac
     8821 ttggcagcct tacgcaactg ctcttcgggg ataccgatag cagcttccag cttaccacca
     8881 tacttgttga tagtatcaac ttcttcctga ggaactgaag aagaaccgtg aagaacgatg
     8941 gggaatcccg gaagtttctc cattacagca tccagaacgg caaattccaa aggaggagga
     9001 accagacgac cggtagcagg gtcaacgtgg cattgttcgg gtttgaactt gtatgcacca
     9061 tgagaagtac cgattgagat agccagtgaa tcgcaacctg tacgggtagc gaagtcaata
     9121 acttcttcag gattagtata tgtatggtgt tctgcagaaa cttcatcttc tacaccggcc
     9181 aatacaccga gttcgccttc tacagttacg tcgaactgat gggcatagtc aactaccttc
     9241 ttagtcagtg caacgttttc ttcgtacgga aggtgtgaac cgtcaatcat tactgaagag
     9301 aaaccggagt cgatacagct cttgcaagtt tcgaatgtat ctccgtggtc aaggtgaaga
     9361 acaatttcag gatgtttgca acccaattcc ttagcgtact caacagcacc ctgagccatg
     9421 taacgcaaca gcgtagcgtt ggcatactga cgggcaccct tagatacctg aagaataacc
     9481 ggagactttg tttcaactgc agccttgatg atagcctgca tctgttccat attgttgaag
     9541 ttgaatgccg gaatagcata tccacctttg atagccttag caaacatctc tcttgtgttt
     9601 accagtccta aatctttgta attaaccatt ttgtttaaat tttattgtta gtgaattaaa
     9661 attctacgca aaagtaatca ttatccttta aagtaaagaa cttgacggga ataaaatatc
     9721 cggctcatcc taccaaatcc attctatttt aaagctattg gcttcattta acagattatt
     9781 gtaatctcta tattacaaac tctttgcatt tatctctgcc agccatactt ttgccatcta
     9841 tacttctatc aacaaaaaag ccggagaaca tgtttgctct ccggcatctg tttacacatt
     9901 attatgtaat actaattttt cagatagatg atggtcggca aatggtcact gtaaccgttc
     9961 agccaagtcc tgcccccatg cgtacgcaag ggggaacctt tgtatttgcc atcctgctga
    10021 atcagataat cgcggatgaa aacttcattg tgatcatagc gcaacccttt cttagccttc
    10081 agcaacggtt tcgaaatgac aatctggtca aacaagttcc acttgccccg atagagcaat
    10141 gtccccactc ccttgtcttc cagcgtcacc caccagggat tgtagaattc gcctttcttc
    10201 acctgcttcg gatatttgcg cgctcccagc acctccatgc tttcgtccat cgggtcgtca
    10261 ttcatatccc ccatcacgat gagcttcagc ttcttgtcgc tacgcatcag agagtccttc
    10321 aaggccttta cctgcctggc tgcatgcaca cgcaccggcg actttgcccc acgggagggc
    10381 cagtggttca ctatcacgca gacacgctct cccgccagtt gtccgtccac aatcaagaag
    10441 ccacgcgtca agtgcaccgt atccccctca aaaggagtgg aaagcaccaa ctttgagtgg
    10501 gtaacgctga attgcttcgg gtcgtacagc aaggcacagt cgatgccccg tctgtccggt
    10561 ccttcataat gcacgaactc ataattggaa atggccggct gcttcacgag gtcttccagc
    10621 acccggctgt tctctgcctc tgccacaccg atgaatgccg gaccttccgg cactaaatca
    10681 cgcgaaaggg accccaacac tttggaaagg ttctgcagct tggactcata cttctttgcc
    10741 gtccactggt aactgccgtt aggcaggaac tcatagtcat tcttacctgc atcatgaatc
    10801 gtatcaaata agttctcaag attgtagaac gcaacactat acagtttccg ttccgcattt
    10861 tgtgccccca gcgttgccac gcacagccag aaagagcata agacaagtag tttcctcata
    10921 aattcacaag attaagtcct gcaaaaatca gaaataaaat gcgataaacc tactaaataa
    10981 aaataaatct gaatttattt tgtagagtct ccaacttgca ctatctttgc gctctgaaaa
    11041 gaagaccatt acactattta ttaccaaaat agtaacagaa tataaatttt taaaagaaaa
    11101 tatcaaaatg aaaaaaggta ttcatcctga aaattaccgt ccggtagtat ttaaagatat
    11161 gtcaaatggt gatgtattct tgtctcgttc cacttgcaac acgaaagaga ctatcgaatt
    11221 cgaaggtgaa acttatccgc tggtaaagct ggaaatctcc agcacttctc acccgttcta
    11281 cactggtaag tccaagctgg ttgacaccgc cggtcgtgtt gataagttca tgagccgtta
    11341 cggtaaccgt aagaaataat cagtttcaag caaactgaaa aaagggagtc tttcactgaa
    11401 aggttccctt ttttgtttcc gcctcccgct gagcgataaa tagggaatct cctatcacag
    11461 aataggggaa aaaacaagaa aggggaaaaa cactttccta tttttgtatc atcgaaaccg
    11521 aaaacatacc ataatcatga aacgactcgc caccctattc atcctaacaa tccttgtcac
    11581 aacggcaggg tttgccaaac ccaagcacaa ggacttaagc ggaaacatcg ccatcaaagg
    11641 agaattgaca aaagagtacc agcaatctcc cgccggtacc ccggtcatta tccgccgggt
    11701 tgtcaaaatg aacaatcccg gtgaaaacag cgataacatt tactatgccg tcgaagtgaa
    11761 tggcatacaa gaaaccattc cttcggatga gatgggtatc attgccatat ccgctccgga
    11821 aacggaccgg gaattctggc agcaaatata cctgaagaat catctttacg aatatttcaa
    11881 cgaccgcggt tacaagcaca aactgcgcca ggaaatcgac gaagaatgcc tggactatct
    11941 cgataaactg aacgagatag cctatcagga cgactacata acctcgtacg tacaaggaat
    12001 attctccaaa ctgaatgcca ccaccattga cagcaatcgt ggagaaagcc tgaacatacg
    12061 tatcatccag tcgtccgaac cagatgcctt catgctttcc aacggctcca tggttatcag
    12121 tacaggcctc ctctgcactc ttgattccga agacgaactg gccgccgtca tcgcatgtga
    12181 gctgggacat ttcgtcctcg accatcaggt aaacaacatt tatcgtgccg agcggcgtgc
    12241 caagcgtgca gctttttggg cagatgtctt tgccactacc gccagcgcag ccctcgatgt
    12301 ggcctactgg gacgataatg aagatgctta tgccgtcagt ctggtggcag atatcggagc
    12361 catcgcttcc cttttgagca ttccggcaac ggaccggttg gggatgaaat acaaaacttc
    12421 ccaggaaatc tcttcagacc gccttgcgcg ccaacttctg gcattcaagg gctataatcc
    12481 cgacggaatc gcatcggccc tcggtaaaat tatagggtat tacaacctgc accaacgcaa
    12541 caaggacatt cctcgctacg gcagcatcgg caacctgcaa aagcgtatag aaaaggccgg
    12601 tgaatcccat agcctgagtg cccgccccta cctacggacc accagcgatg tcgtttcttt
    12661 caacgcaagt atgaactacg ccaacaagcg ctataaggaa actgcccggc tgatacgcaa
    12721 gaacattgac aacagactag ccacggacaa tgactacatc atcctggtaa aagcggaaat
    12781 ggcactgtct aatacggaag aagtgaacaa ccgctgcctc gccatgcttg ataaagccca
    12841 ggagatggca ggaacaagcc ccaatctgga catatataaa caaaaaatac tattattgat
    12901 gcgcatgaac aaacaagccc aagccgctga tatactgaaa gaatatatca ccttgctttc
    12961 ggcctacgaa ggccagggca tagaaggaac cgaaaaggaa tggaccaata aagagatagg
    13021 ttgggcaaac caaatgctgg acaggataag cagaatatag agaaaggaat aactaagaat
    13081 gaagaatgaa gaatttgtca tgcggcatca ttgcgcagcc aaattcttca ttctcagtca
    13141 tttattcaaa ctactgtttg cggaacggcg gcttcacaac cacagctttc agcttacgtc
    13201 cccgcatgtc aatgcagatt tccgtaccga ccttgctgta ttcgggtctg atatacccca
    13261 ttccgatacc aatcttacgg gtaggcgaca tagttccgga ggtaaccaca ccgatggcaa
    13321 taccgtctgt actatacagc tcgtaaccat gacgggggat accgcggtct atcatctcaa
    13381 atcccaccaa cttacgggta gtgccttccg ctttctgttt ttccagcatc gggcgattgg
    13441 tgaagttctt tccctccaca aacttggtaa tccatcctaa acccgcttca atgggcgaag
    13501 tggtgtcatc caaatcattg ccatacaaac agaatcccat ttccagacga agcgtatcgc
    13561 gcgcacccag accaactggc ttaatgccga actccgcgcc tgcctcgaac acggcatccc
    13621 aaatcttcat ggcagcctcc ggatagaagt aaagttcaaa accacccgcg ccggtatatc
    13681 cggtattgga gataatgaca tccttttctc cggcaaactc accgtgggta aaagtatagt
    13741 aaggaaggtc ggaaagatta atggaagtca gcttctgcaa agcctgaata gccttcggtc
    13801 cttgcacagc aagctgtgcc atgtgctcgg aagcattttc caattcagcg ccttccgtgt
    13861 tatgagacac acaccagttc cagtctttct caatgttcga cgcattcacg acaagcaggt
    13921 atttctccgg ctcataatga tagaccagaa ggtcgtccac aatgcctcca ttttcatttg
    13981 ggaagcaggt atactgtact ttccccggtg tgagggcagc tatgttattg gaagtcactt
    14041 tctgcagaaa gtccaaagca tggggacctt tcacccaaaa ttctcccatg tgtgagacgt
    14101 cgaatacacc gacaccctga catactgtaa gatgctcgtc aatgatgccg gaatactcga
    14161 taggcatatt atatcccgca aactcgtgca tcttggcacc cagcgagatg tgtttttcgg
    14221 taaacggagt ggttttcatg gaactattag agttatgagt tatgaattat ctatttgctt
    14281 gctacgagct cggcaatctt gacgatgacg ttcatggctt tctccatgtt ctggataggc
    14341 acgaactcat agcggccgtg gaagttcaag ccaccggcaa agatattggg acaaggcagg
    14401 cccttgaaag agagctgggc gccgtccgta cctccgcgaa tggcttttac acgaggctct
    14461 acacctaccg ccttcatggc ggcaaaagcg gtgtcgatga tatgcatcac cggttcaatc
    14521 tgctcgcgca tattatagta ttggtcgcga agttccagag tagcggtacc cggaccgtat
    14581 tcttcattga tttttgccac aagacgttcc atctccttct tgcgctcttc gaagcgggtg
    14641 cggtcgtggt cacggataat gtaag
//
