LOCUS       c00011_gnlPro..         6027 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OOPKPEOC_11.
ACCESSION   c00011_gnlPro..
VERSION     c00011_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 02:18:04
            Original ID  :: gnl|Prokka|OOPKPEOC_11
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6027
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6027
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[960:5199]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      961..5199
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..6027
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6027
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..161)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_1"
                     /sec_met_domain="IlvN (E-value: 1.4e-10, bitscore: 29.7,
                     seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNG"
     CDS             complement(212..964)
                     /locus_tag="ctg11_2"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYVAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVMFTEK"
     CDS             complement(961..1521)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_3"
                     /sec_met_domain="ALS_ss_C (E-value: 3.6e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             complement(1554..3305)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.1e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRQAAELI
                     NGAERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTDHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             complement(3397..5199)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_5"
                     /sec_met_domain="ILVD_EDD (E-value: 3.3e-219, bitscore:
                     717.3, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHQLRSSFSTQGRRMAGARALWTANGMKKEQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQFVKEEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVGDKEVAQIEQHACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRKRLFEDAAKLIVANAFRYYEEGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGADFKMDDIDMLSRKTPCLCKVAPNTQKYHVQDVNRAGGIIAIMDELAKGG
                     LVDTNVRRVDGMTLAEAIDRYSITSSNVCKEAIKKYSSAAAGKFNLVLGSQNASYKELD
                     TDRATGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDA
                     ACDGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARPMTPVTRNRE
                     VSKALKAYASMVSSADKGAVRLID"
     CDS             5690..6025
                     /locus_tag="ctg11_6"
                     /transl_table=11
                     /translation="METVENKYITVAYKLYSIENGEKDFEEEAPVEHPFQFISGLGMTL
                     EPFEAQIKDLQIGDKFDFTIPASEAYGEYDDDHVIDLPKEIFMIEGEFDSDRVVEGAVI
                     PLMTSEGQ"
ORIGIN
        1 aaaccgttat cacgcaagtt gcaagcctgg cccgggcctt gtacgccata accgattact
       61 gcaattgttt catctttcaa aatctcacgt gctttttcca aaggaaattc ttcgcgggtc
      121 attacattct caataacacc gccaaaattc aattgtgcca ttttttgttt taatttttat
      181 ttgtggctta cgccaacgtt gataaattta tttatttctc tgtaaacatc actttagagc
      241 gacagaccac ttcgctgcca ttctttttca cctccacatc gtaaacgccc tcaccggcat
      301 catccatgaa caaagtcaac tcatccccat aatagctttc ggctacatat gccatttcaa
      361 aacgacggat gcgcttctcc ttatacatct ctatcgggaa caaatcaagg atatgctcaa
      421 tgtaacggat gctgttcaca tgcccgttaa tgtcaatatc actgtatttg gctaccaaag
      481 cagcaaccgg ttcctttgag gccaccttta tccgcgaagg tttttctatc gggcaaggct
      541 catcgcaaac ataatctaca atgctgccac tatgaagagc cagcaaatct gccggcttac
      601 gggtattcat gctaatcatc gcccaaacgg aacgtgcata cccaatcttc ttgccctcct
      661 tatcgatgat agcgaaatta cggtctgtaa aaaggcgata gacattctcc acccaagtct
      721 gaatggagaa atcttcgtac tgataaggca tttcatccag ttcgacagcc agacgggaca
      781 atacccaagt ataattgtcc tcgtttagag tcgcgatgcc aaaaccgcgg tcgctggcat
      841 ggaaacccgc acaattcaac aaatggttgc ccaatactcc cattgtcagc cgtccggtaa
      901 agtcgacatg aaacggttcg gcaacaaact tgtaggtacc tattttattg ttctcgctca
      961 tcatgattcc tggtgtttac tttgacgata ttttgcttca cggtccgcca gatattcatt
     1021 gacacgctca aagcagctgg tcgtaatggc tacgcgaccc gaacggacga actgaagtac
     1081 gcaatccaac tggcgcaact cctcataaag attggttatt tcctcactca tgccattctt
     1141 ctcaacaatg gcaaatacag cattcacctc cacaatacgg gcattgtact tacggattac
     1201 tttggacacc tccggttttt cttccagcgt aggggtcgtt attttataaa gggcaatctc
     1261 gtgctgatag atttcatcat ccgtgaaata atgggcttgc agcacatcta ttttcttggt
     1321 aatctgcttg gtcacctttt caatggtatc cttatccgtc caagcggtaa tggtatattt
     1381 atgtaccccc ttgatggagg aggccgatac attcaagctc tcgatgttta tctgccggcg
     1441 ggtaaacaca gccgtcacct gattcagcaa accggcaaag ttttccgaat gaacaatgat
     1501 tgtatatagt tttttatcca tagatagagt aaattcttta atttcgcatg acttcagcat
     1561 tccaacaaca tctgattgac cgaaccgccc ggaggtgtca tcggcattac atttccttct
     1621 tcctccacac aagcttcgag caggaatggt ccgtcagtcg ctatcatctc gtcaatcgct
     1681 tttgccagct cctcgcgggt cattaccctg cgtgcaggaa tatcatatgc cgaagcaatc
     1741 ttcatataat ccggattcat catcggagta aacgaataac gacgattgaa gaacatcgcc
     1801 tgccattgac gaacattgcc caggaagtta ttgttcaaca gaatcatctt caccggagcc
     1861 ttttgttcca tgatggtacc cagttcctgc aggttcatct gcaagccgcc gtctcccatg
     1921 aatacgcata ccgtgcggtc cggacgtcca aaagtggcac cgatagctgc cggaaggccg
     1981 aagcccatag tacccaggcc accggaagta acaatgctac gttccttgct gtatttgaaa
     2041 taacgggcgg acatcatctg attctggccg acatcagtca ccaatatcgc ctcgttatgg
     2101 gtagcctcac tcacagcacg caccacctca cccatgctta gcgcttttcc tgccggatgt
     2161 aattccggac ggattacctt ttcctcttcc acttcctcgt attgccggaa actgtcaatc
     2221 cattcctgat ggttggcggg ttccagcaat tgggtaacgg cagccagtgt ctctttgcaa
     2281 tctcccagga cagcaacatc agtctttaca ttcttatcta tttcggcagg gtcaatatca
     2341 aagtggataa tcttcgcctg cttggcatat gtttccaatt tacccgtcac acggtcatca
     2401 aagcgcatgc ctacggcgat aaggacatca catttattgg tattgatatt gggccccagg
     2461 ttaccgtgca taccaagcat tcctttgttc aacggatggt ccgtaggcaa tgcggaaagt
     2521 cccaataaag tgcatccggc aggcattccg gctttctcaa tgaaagcacg aagctcttgc
     2581 tgggcttctc ccagctccac gccttgtcct accagcacca aaggccgttc cgcaccattt
     2641 attaattcag cagcctgccg tatggcctcc ggctccattt cgggaactgg aagatagcta
     2701 cggacatagt ccaccttagt aggcgcatat tctgttttct ccacttgggc gtttttagca
     2761 aaatccagca cgaccggtcc cggacgtccg ctctttgcca catagaaagc acgtgccact
     2821 gcccaggcca catcttctgc acgacgaatc tggtaactcc atttcgtgat aggctgagta
     2881 atgcctacca agtccacttc ttgaaatgca tccgtaccca agaagttcgt ccctacctgg
     2941 ccggcaatga caacgatagg cgtactgtca atcatggcat ctgcaatgcc cgtgatagta
     3001 ttggtagcac ccggtccact ggtaaccaga caaacgccaa cctcgcctga tacacgtgca
     3061 aagccttgtg ccgcatgggt tgctccttgt tcatggcgaa ccaagatgtg gttcaattcc
     3121 ttccggtggt cgtataaggc atcgaatacc ggcatgatgc tccctcccgg ataaccgaaa
     3181 atagtcttta ctccctgatg ctccagagag cgcatcaatg cttctgcgcc tgttattaga
     3241 gcctcacccc gaccctctcc ttgggagagg gaggaaaagt tactcttttt attattatca
     3301 gccatacttt atctattcat tatatttaaa agctcaatag tagcttgaaa aatttgtttc
     3361 attctctcct cccctcgctt tcggaaaggg gggcttttaa tcaatcagcc tcacagcccc
     3421 tttgtcagcg gaactcacca tactggcata tgctttcaat gctttggaga cttcacggtt
     3481 gcgggttacc ggagtcatag ggcgtgctgc aagctcttca tccgtcaact tcacattgat
     3541 agaacggttc ggtatatcaa tttcgataat gtccccatcc ttaatcttgc cgatattacc
     3601 accggcagcc gcttcgggag aaacatgtcc gatacttagt ccggaagtac caccactgaa
     3661 acgcccgtcg gtaatcaatg cacactcctt acccagatgg cgggatttga tataagaagt
     3721 aggataaagc atctcttgca tacccggtcc acctttcggc ccttcgtgag tgatgacgac
     3781 gacgtctcca ctgaccacct ttccacccag aataccgtca caagccgcat cttgtgagtc
     3841 gaagactttc gctggccccg taaatttcca gatactctcg tctacaccgg cagtcttgac
     3901 aacgcaaccg tcctgagcta tatttccctt caaaaccgcc agaccgccat ccttgctgta
     3961 tgcatgttcc aaatcacgga tacaaccggt cgcacggtcc gtatcgagtt ccttataaga
     4021 cgcattttgt gagccgagta ccagattgaa ctttccggct gccgcactgg agtatttctt
     4081 gattgcctct ttacatacat tagagctggt aatactatac cggtcgattg cctctgccaa
     4141 cgtcattcca tccacacggc ggacattcgt atcgaccaat ccgcccttgg caagctcatc
     4201 catgatggca atgatgccac cggcacggtt aacgtcttgt acatgatact tttgggtatt
     4261 gggagctacc ttgcataagc agggggtctt gcgagagagc atgtcaatgt cgtccatctt
     4321 aaaatccgct ccggcttcgt gagccacagc caacaaatga agtactgtat tagtggaacc
     4381 gcccatcgca atatccagcg tcatggcatt caaaaatgcc tcgcgagtag caatactgcg
     4441 cgggagtaca ctctcatccc cttcttcata atatctaaag gcattcgcta caatcaactt
     4501 agctgcatcc tcaaacagtc tcttgcgatt ttcgtgagtg gctacaatcg tgccgttacc
     4561 gggcagtgcc aatccaatcg cttcattcag gcaattcatg gaattagcgg taaacatgcc
     4621 tgagcagcat ccgcaagtgg ggcaggcatg ttgctcaatc tgtgccacct ctttatcgcc
     4681 cacactttca tcagcagatt taatcatggc atcaatcaaa tccaaatgct gtccgttcca
     4741 ttccccggct tccatcggac cgcctgaaac aaacacagtc ggtatattca gcctcatagc
     4801 cgccatcaac atccccggag taatcttgtc acagttactg atgcaaacca tagcatccgc
     4861 cttatgggca tttaccatat actccacact atcggcaatg atatctcttg aaggcaggga
     4921 ataaagcata ccgtcgtgtc ccatagcgat accgtcgtca atggcaatcg tattgaactc
     4981 cgcagcaaaa caccccagct tttcaatctc ttcctttaca aactggccta tttcgtgcag
     5041 gtgtacatgc ccggggacga attgtgtaaa tgaattgact atagcgataa tgggcttacc
     5101 catctgttcc ttcttcatac cattcgccgt ccacaatgca cgggctcccg ccatgcggcg
     5161 accttgtgtg ctgaacgagc tgcgtaactg atgcttcatt ttcaaatctc cttttaatga
     5221 aaaagcctct cccactatag tgagaaaggc ttaataaatt atcttctaac gtacgaatac
     5281 atacataacc tttctcacgc tcttgatgcc accaccacga cgcgaataat atgcaggact
     5341 gccaggttaa tagatgtatg taaattcata acttaattct tcttttttgt ttcaaacgtg
     5401 ctgcaaaggt aagggctttt ttataatctc caaacaaatt gaagaaaaaa ataagataaa
     5461 tatgaataat cgtaagaaaa tatcgcccta aaatcctatt ttatcactta acagttctaa
     5521 atagaaccat tcagacagcc aatgtaaatg tattgccaat cattgaaacc atttaataat
     5581 ctgaaaatta ccaaaggctc tctacatccc gaaacaaata attcgtatct ttgtctcttc
     5641 aaatactcaa aaaaacagta tttactaatt aaataaagat agaaaattaa tggaaacagt
     5701 agaaaacaag tacatcaccg tagcatataa gctgtactca atcgaaaacg gagaaaaaga
     5761 tttcgaagaa gaagcacccg tagagcatcc ttttcagttt atctcaggtc tgggaatgac
     5821 actcgaaccc tttgaagccc agataaaaga cttgcaaata ggcgataaat tcgactttac
     5881 cattccggca tcagaagctt atggtgaata tgacgacgac catgttattg acctccccaa
     5941 agaaatcttc atgatagaag gagaattcga cagcgatcgt gtagtagaag gtgccgttat
     6001 ccccttgatg acttctgaag gtcaacg
//
