LOCUS       gnlProkkaPJCDOOPK_55   16210 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PJCDOOPK_55.
ACCESSION   gnlProkkaPJCDOOPK_55
VERSION     gnlProkkaPJCDOOPK_55
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 03:24:48
            Original ID  :: gnl|Prokka|PJCDOOPK_55
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16210
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16210
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5859:6210]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5860..6210
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..16210
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16210
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             675..3503
                     /locus_tag="ctg55_1"
                     /transl_table=11
                     /translation="MKNLIALTLLLGGSTLLCAQKPAKTPATYKPVKSEMYRKGWIDFN
                     KNGVKDVYEDPSAPLEARIENLLQQMTLDEKTCQMVTLYGYKRVLKDDLPTPEWKELLW
                     KDGIGAIDEHLNGFQQWGLPPSDNAYVWPASRHAWALNEVQRFFVEDTRLGIPVDFTNE
                     GIRGVESYRATNFPTQLGLGHTWNRELIRQVGLITGREARMLGYTNVYAPILDVGRDQR
                     WGRYEEVYGESPYLVAELGIEMVRGLQHNHQVAATGKHFAAYSNNKGAREGMARVDPQM
                     SPREVENIHIYPFKRVIREAGMLGVMSSYNDYDGIPVQGSYYWLTTRLRGEMGFRGYVV
                     SDSDAVEYLYTKHGTAKDMKEAVRQSVEAGLNVRCTFRSPDSFVLPLRELVKEGGLSEE
                     VINDRVRDILRVKFLIGLFDAPYQTDLAGADREVEKEENEAIALQASHESVVLLKNADE
                     LLPLDINSTKKIAVCGPNANEEGYALTHYGPLAVEVTTVLEGIQEKTKSKAEVLYTKGC
                     DLVDAHWPESEIIDYPLTDDEQAEIDKAVENARQADVAVVVLGGGQRTCGENKSRTSLD
                     LPGRQLQLLQAIQATGKPVVLILINGRPLSINWADKFVPAILEAWYPGSKGGTALADIL
                     FGDYNPGGKLTVTFPKTVGQIPFNFPCKPSSQIDGGKNPGPTGNMSRINGALYPFGYGL
                     SYTTFEYSDLDITPRVITPNESATVRLKVTNTGKRAGDEVVQLYIRDVLSSITTYEKNL
                     AGFQRIHLEPGEAQELSFTIDRKHLELLDADMKWVVEPGDFVLMAGASSEDIRLNGTLT
                     VEDYQTRAKAIEAQKPAKRVSASTNPEDAENVLDEKINTAWQGNKGDYITFALKNGAKV
                     DKVAIAFTRDNNLPATFEIQLSGGGGQFLTVYSGTVSEYGKLISYPFKGTTASDLRIVL
                     NDDRVSIAEVKF"
     CDS             3626..4732
                     /locus_tag="ctg55_2"
                     /transl_table=11
                     /translation="MLGLGLTACGSSPKGTNGDQDELAMLIGTYTNGSSKGIYTFRFNQ
                     ETGTAVPLSSAALPNPSYLVPSGDGEFVYAVSEMNDSTAALSSLSLDRETGELRLLNTV
                     PTFGADPCYVATNGREVLTANYSGGTMSVFPLQKDGTLAPADTLFQGSATGPDAIRQAT
                     PHIHCTVFSPDGKYIFATDFSADRILRFVMHPDDPIPHASLEAVDIEADSGPRHLTFSP
                     NGKFAYLITELSGKVIAFSYDDGCLEQIQTITADTVAARGSADIHLSPDGKYLYASNRL
                     KEDGIAIFAVNPENGTLAKVGYQPTGIHPRNFNITPNGKYLLAACRDSNVIQVYKRNEV
                     TGLLEDTHQDIVVDMPVCVQFVSSVNNL"
     CDS             4803..5852
                     /locus_tag="ctg55_3"
                     /transl_table=11
                     /translation="MKKNILMLSALFLSITAMAQTDVTTGVMRGKDYGVTYMLPKTEIE
                     IVLQATKHTYTPGEFCRYADRYLRLNNVSAEPEEFWTLDKIETRIAGVPDKDNVYFVKM
                     KDKTVAPLMELTEDGIVRSINIPFSGKPAAKTPEAKATESSIDPRSFLTEEILMSNSSA
                     KMAELVAKEIYSIRESKNALLRGEADNMPKDGAQLKLMLDNLNQQETAMTEMFSGKIKK
                     EPKTFTIRLTPKEMKDEVAFRFSRKLGVVANNDLAGEPYYISVTDLKSPDVSATEEGKK
                     KVDGVAYNLPGKAQVTLVYNNKKLFDDQLPITQFGTVEYLAPVLFNKNSTIKVLFDTAT
                     GGLIKVDRE"
     CDS             complement(5860..6210)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_4"
                     /sec_met_domain="PqqD_RRE (E-value: 8.5e-10, bitscore:
                     30.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.7e-16, bitscore: 50.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIPEGKVSLLDAVPVRCGHITTEWEGECAVLAYPRFKYEWMRRF
                     LLPKGMSPDIHVRLEEHGTAVWNLIDGHRTVREIIYLLARHFGEEENYIPRVTAYVMQL
                     RKDGFIQLTIRN"
     CDS             complement(6233..7624)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 101.4; E-value: 7.2e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg55_5"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMAAYYVNDVVAPLKTMLE
                     TDLAWSSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTGLAGADATLFGINEIFGYKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPLARAFGISTPVLLGLVLLLGGMIAFFVFAVMDKKL
                     DKQMEAAAIAAGTEDEEEKFSFKDVKNILVNPGFWLIALLCVLFYSCVFPFQKFASELM
                     IIKYGINENVAGTFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PDINYWLVAIVLMIILGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGWVLDAYCISGKKPDGTNMYDYTVPMCIFTGIACLSLIVALLLKKADKKYGYKLEE
                     PNIQK"
     CDS             complement(7778..8143)
                     /locus_tag="ctg55_6"
                     /transl_table=11
                     /translation="MLIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRKTTDFLEKA
                     TWTLAAVMVVFSIVSAYTIPSSTGKGGDVILEQAQQEEKTNPYNMPVGTEAPQSEAPAA
                     TTPAETPAPAAEAPAAE"
     CDS             complement(8172..8945)
                     /locus_tag="ctg55_7"
                     /transl_table=11
                     /translation="MTPTHLQQWIQHPETLNRDTLYELRTLVARYPYFQSLRLLYLKNL
                     YLLHDINFGAELRKAVLYVADRRVLFYFIEGDRYTLKSRKVSSLFSGDLEKEPSVDRTL
                     SLIDAFLATVPEEHSQHTELDYAVDYTAYLMQEEPGVDAEDESEVPKLRGHELIDDFIQ
                     KSESSDASDTRREFLVEKEEETEEEEEPSVSPVTEELDDSCFTETLAKIYIKQHRYDKA
                     LEIIKKLSLNYPKKNAYFADQIRFLEKLIINAKSK"
     CDS             complement(8950..9474)
                     /locus_tag="ctg55_8"
                     /transl_table=11
                     /translation="MDWIKKAAFASLLVSLLFLVNSCSMKLGLAPISSIDYTKVKTISI
                     ADFQNRAEYVYAPLATEFNQKMKDMFIQQTRLQLVNSGGDLEIDGEITGYNQYNESVDA
                     SGYSSKVKVTLTVNVRYTNNTNHEEDFEQQFSAFQTYDSSKLLTEVQDQLITLMVKDIA
                     EQIFNATVANW"
     CDS             complement(9461..10711)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 380.4; E-value:
                     2.1e-115)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg55_9"
                     /transl_table=11
                     /translation="MTKAEIQQVKLRFGIIGNNEALMRAIDIAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EANGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVEKTDVRIVAATNVNLTQAI
                     ADGRFREDLYYRLNTVPIQVPPLRERGEDVVLLFRKFASDFAEKYRMPAIQLTEDGKQV
                     LLGYSWPGNVRQLKNITEQISIIETNREINASILKGYLPEQNNMQRLPALFGVKEDKSF
                     GSEREILYQVLFDMRQDVTDLKKLVHEIMAERGTVANPAVATSAYYTPATPAVVPPVTS
                     SVPTIIHPSAKPVTPVDDDFQDTEEYVEESLSLDEVEKEMIRKALEKHHGKRKSAAQDL
                     NISERTLYRKIKEYGLD"
     CDS             complement(10713..11810)
                     /locus_tag="ctg55_10"
                     /transl_table=11
                     /translation="MEDNKIRVGITQGDINGVGYEVILKTFADPVMLELCTPIIYGSPK
                     VAAYHRKSLDLSTNFSIVNSASEAVPNRLSVVNCTDDEVKVEFSKPDVEAGKAALGALE
                     KAIEEYKEGMIDVIVTAPINKHTIQSEEFAFPGHTEYIEQKLGDGEKALMILMKDDFRV
                     ALVTGHIPVKEIAGSITKELIQEKLKIFNRSLKQDFAISAPRIAVLSLNPHAGDGGLLG
                     TEEQEIIIPAINEMAAKGMLCYGPYPADGFMGSDNFTHFDGILAMYHDQGLAPFKALAM
                     DEGVNYTAGLPVIRTSPAHGTAYDIAGKGIASEDSFRQAIYVAIDVFRNRQREKEAHAN
                     PLRKQYYEKRDDSDKLKLDSVEEDL"
     CDS             complement(11816..12871)
                     /locus_tag="ctg55_11"
                     /transl_table=11
                     /translation="MRKHLFYLSMVLVLTLFSACGGGKKGVFTPTSSGRAYEVLVVVEP
                     GLWERPAGRALFDVLDSDVPGLPQSERSFRIMYTAPSNYDATLKLIRNIIIVDVNKDLY
                     TQPKFKYARNVYAAPQSILTIQAPDEASFEKFVEENRQVIIDFFTHAEMNRQISVLKDK
                     HSDYIATKVKSLFDCDVWVPGELTSTKEGENFFWAGTNAATGDQNFVIYSYPYTDKDTF
                     TKEYFVHKRDSVMKANIPGAREGMYMSTDSLMTDVRPISVQGDYALEARGLWRIKGDFM
                     GGPFVSHVRLDKANQRIIVSEIFIYSPDKMKRNLVRQMEASLYTLKLPGSKLEGAEIPV
                     GVTAKDTTNNK"
     CDS             complement(12942..13994)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_12"
                     /sec_met_domain="PF04055 (E-value: 8.1e-17, bitscore: 53.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNDMQKRPLLGLTLSELQNVVKNLGMPGFSAKQIASWLYDKKVT
                     SIDEMSNLSLKHRELLKEIYEVGAEAPVDAMRSVDGTVKYLYRAGEGHFVEAVYIPDED
                     RATLCVSSQVGCKMNCKFCMTGKQGFTANLTSNQIINQINSLPERDKLTNVVMMGMGEP
                     LDNLDEVLKALEIMTASYGYAWSPKRVTLSSVGLKKGLQRFIEESDCHLAISLHSPIPL
                     QRRELMPAEKAFSITEIVELLRNYDFSKQRRLSFEYIVFKGVNDSLPYAKELLKLLRGL
                     DCRINLIRFHAIPGVNLEGADMETMTAFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTA
                     KQEENKEELI"
ORIGIN
        1 caccatatat ttacaaatat tagctaatac tgacttttcg tgataaaaac aataatcttc
       61 catacataga atatgtgcac cccattgtca tcaatgttca aacagctacc aaagccagta
      121 tccgttgacg gaattacccc ctgcaagagg gaatatctat cttctgtaat ggatatttgc
      181 acaaaagaga tgggaagtta acggaaaaag tctctgaagt taactgaaaa accggaaaga
      241 attaaggaag caatctatcc caaactttgg tttttccata cccagccttg agatgtctaa
      301 accaaggttt ggtttagaca tcccaaggtt gaaaagaaag ttcttccgta caagcaacaa
      361 ttccgccaac agattcctat tatataaata caccctcgtt taacagatgt agccgtaata
      421 cttgtataca ccgcgattgc atctactttt caggttatta tagtgttctt tctttttaaa
      481 agtgaatgat atgtttcgtc taataatgat ttgaattccc cggtagcgtc ttggaggata
      541 tttttagtaa gaggaagacc cttcggacaa taaaagccga tacttcggac tattttatcc
      601 ctttatttca cacattagcc gtatttttgt caacaaaaga aacaataata accaagagat
      661 ttttagaaca tatcatgaag aaccttattg ccctaaccct gctgcttgga ggaagcacac
      721 tgctctgcgc acaaaagcct gccaaaacac cggcaaccta caagccggtg aaaagtgaaa
      781 tgtaccgcaa aggttggata gacttcaaca aaaacggagt gaaagacgtg tacgaagacc
      841 cctccgcccc gctcgaagca cgcatcgaaa acctgctgca acagatgacg ctggacgaaa
      901 agacctgcca aatggtcacc ctctacggct acaaacgcgt actgaaagac gacctcccca
      961 cccccgaatg gaaagagctg ctctggaaag acggcatcgg cgccatcgac gaacacctga
     1021 acggcttcca gcaatggggg ctgcctccct cggacaatgc ctacgtctgg cccgcctcgc
     1081 gccacgcctg ggcactgaac gaggtgcaac ggttctttgt ggaagatacc cgtctcggca
     1141 tccccgtaga ctttaccaac gaaggcatac gcggcgtgga aagctaccgc gccaccaact
     1201 tccccaccca actgggactg ggacatacct ggaaccgtga actgattcgc caagtaggac
     1261 tcatcaccgg acgcgaagcc cgcatgctgg gctacaccaa cgtctacgcc cccatcctcg
     1321 acgtaggacg cgaccagcgc tggggacgct acgaagaagt ttacggcgaa tctccctacc
     1381 tcgtagccga actgggcatc gaaatggtgc gcggcttgca gcacaaccac caagtggccg
     1441 ccaccggcaa gcactttgcc gcttacagta acaacaaagg cgcccgcgaa ggcatggcac
     1501 gcgtggaccc gcaaatgtcg ccgcgcgaag tggagaacat acacatctac cccttcaaac
     1561 gcgtcatccg ggaagctggc atgctgggcg taatgagttc gtacaacgat tacgacggca
     1621 tccccgtgca gggcagctac tactggctca ccacccgcct gcgtggcgaa atgggattcc
     1681 gtggctacgt cgtatccgac agtgacgccg tagaatacct ctacaccaag cacggcaccg
     1741 ccaaagacat gaaagaagcc gtccgccaaa gcgtggaagc cgggctgaac gtacgctgta
     1801 ccttccgctc gcccgactcc ttcgtccttc ccctccgcga actggtgaag gaaggcgggc
     1861 tgagcgaaga agtcattaac gaccgtgtgc gcgacatcct ccgggtaaag ttcctcattg
     1921 gtctgttcga tgccccctac cagacagacc ttgccggtgc cgaccgtgaa gtggaaaaag
     1981 aagagaacga agccatcgcc ttgcaggcat cccacgagtc cgtcgttctg ctgaagaatg
     2041 ccgatgagct gttgccctta gacatcaact ccaccaagaa gattgccgtc tgtggtccca
     2101 atgccaatga agaaggctac gcgctgaccc attacggccc acttgccgta gaagtgacca
     2161 ctgtactgga aggcattcaa gaaaagacaa aaagcaaggc agaggtgctc tacaccaaag
     2221 gctgcgacct agtggatgcc cactggcccg aaagtgaaat catagactat cctctgaccg
     2281 acgacgagca agccgagata gacaaagccg tagaaaatgc ccgccaagct gatgttgccg
     2341 tcgtagtatt gggcggcgga caacgcacct gcggcgaaaa caaatcgcgc accagcctcg
     2401 acctgcccgg ccggcagttg caactgcttc aagccataca agccacgggc aagcccgtcg
     2461 tactgatact catcaacgga cgcccgctct ccatcaactg ggcagacaag ttcgtccccg
     2521 ctatcctcga agcctggtat cccggctcca aaggcggaac agccctggcc gacatcctct
     2581 tcggcgacta caaccccggt ggaaagctga cggtgacctt ccccaagacc gtagggcaaa
     2641 tccccttcaa cttcccctgc aaaccttctt cacagataga cggcggtaag aatccgggac
     2701 ctacgggcaa catgtcacgc atcaacggag cactctaccc cttcggttac ggcttgagct
     2761 acaccacctt cgagtactcc gacctcgaca tcaccccccg agtcatcacc ccgaacgagt
     2821 ctgccaccgt ccgcctgaag gtgaccaaca ccggcaaacg tgccggagat gaagtagtgc
     2881 agctctatat ccgcgacgta ctgagcagca tcaccaccta cgaaaagaat cttgcaggct
     2941 tccagcgcat ccacctcgaa ccgggcgaag cccaggagct gtccttcacc atcgaccgca
     3001 agcacctgga gcttctggac gccgacatga aatgggtggt ggaacccggc gacttcgtac
     3061 tcatggccgg cgcctcttcc gaagacatcc gcctgaacgg aacgctgacc gtagaagact
     3121 accagacccg tgccaaagcc attgaagccc aaaaaccagc aaagcgtgtg agtgccagca
     3181 ccaacccaga ggatgccgaa aacgtgctcg acgaaaaaat caataccgca tggcaaggaa
     3241 ataagggaga ttatattacc tttgccttga agaacggagc caaggtagat aaagttgcca
     3301 ttgcctttac acgtgacaac aacctgccgg caaccttcga aatccagctc tcgggcggtg
     3361 gcggacagtt cctcaccgta tattcgggca ccgtcagcga atacggcaaa ctgatttcct
     3421 atccgttcaa aggcactacc gccagcgacc tccgcatcgt gctgaacgat gaccgcgtca
     3481 gtattgccga agttaaattt taatgtgcta atgtgccaat atgctaatgt accaatgacc
     3541 atgcagcata tacagcgcag ccaattagca cattagcata ttggcacatt aacacattaa
     3601 attaatgaaa acacttcttt tctgtatgct cggattaggt ttgacagcat gtggctcttc
     3661 tccaaagggc actaacggtg accaggacga actcgccatg ctaataggta cttacacgaa
     3721 tggctcaagc aagggtatct ataccttccg ctttaatcag gagacgggaa cagccgttcc
     3781 gctcagttca gcggcattgc ccaatccctc ctacctcgtc ccctcgggag atggcgaatt
     3841 tgtctatgcc gtcagtgaaa tgaacgacag cacagcagcc ctcagctccc tttccttaga
     3901 ccgggaaacg ggagaactgc gcctgctgaa caccgttccc accttcggcg ccgacccctg
     3961 ctacgtggcc accaatggcc gggaagtgtt gactgccaac tacagcggtg gaaccatgtc
     4021 cgtctttcct ttacagaaag acggtacttt ggctcctgca gacacgctct ttcaaggctc
     4081 tgccaccggt cccgacgcca tacggcaagc cactccccac atccattgca cggtcttttc
     4141 accggacgga aagtatatct tcgccaccga cttcagtgcc gaccgcatcc tgcgctttgt
     4201 gatgcacccc gacgacccta ttcctcatgc ttctctggaa gccgttgaca ttgaagcgga
     4261 ttccggcccg cgccatctga cattcagccc taacgggaag tttgcctatc tcatcaccga
     4321 actgtccggt aaggtcattg ccttcagtta cgacgacggc tgcctggaac agatacagac
     4381 tatcacagcc gacaccgtag ccgcccgtgg aagtgcagac atccacctca gtccggatgg
     4441 gaaatacctc tacgccagca accgtctgaa agaagacggc atcgccatct ttgccgtgaa
     4501 tcccgaaaat gggaccttgg caaaggtagg ttatcagccc accggcatcc atccccgcaa
     4561 cttcaacatc acgcccaacg gtaaatactt gcttgccgcc tgccgcgaca gcaatgtcat
     4621 tcaggtatac aaacgaaacg aagttaccgg actcttggaa gatactcatc aggacattgt
     4681 agtcgacatg ccggtttgcg tacagttcgt cagctctgtt aataatttat aaagcaatat
     4741 ttagcaaaga taacttcatt aactttgtcc cttagctaaa tcagtctaaa cgaatgtaca
     4801 ttatgaagaa gaatatattg atgctctcag ctctgttctt gtctatcact gccatggcgc
     4861 aaacagacgt aaccaccggt gtgatgcgtg gcaaagacta cggagtgact tatatgttgc
     4921 ccaaaacaga aatagaaatc gtattgcaag ccaccaaaca tacttacact cccggagaat
     4981 tttgcagata tgccgaccgc tatctgcgtc tcaacaacgt gtctgccgaa cccgaggagt
     5041 tctggacact ggataagata gaaacccgca tagccggtgt accggataag gacaacgtct
     5101 atttcgtgaa gatgaaagac aagaccgtag caccccttat ggagcttacc gaagacggaa
     5161 ttgtccgctc catcaacatt ccgttcagcg gtaagcctgc tgccaagacg cccgaagcca
     5221 aagccaccga aagcagcatt gacccacgca gttttctgac ggaagaaata ctgatgtcca
     5281 actccagtgc caagatggcc gagctggtgg ctaaggaaat atacagcatc cgcgaaagca
     5341 agaatgccct cctgcgcggc gaagcagaca atatgcccaa ggacggcgcc caactcaagc
     5401 tgatgcttga caatctgaac cagcaggaaa cggctatgac ggaaatgttc tcgggcaaaa
     5461 taaagaaaga acccaagaca ttcaccatcc ggctgacgcc taaagagatg aaagatgaag
     5521 tggctttccg tttttcccga aagctgggag tggtggccaa taatgacctt gccggtgaac
     5581 cgtattatat cagcgtcacc gacctcaaaa gtcccgatgt atctgccacc gaggaaggca
     5641 aaaagaaagt ggacggtgta gcctataacc ttccgggcaa ggcacaagtg acattggtgt
     5701 ataacaataa gaaattgttt gacgaccaac ttcccattac ccaattcggc accgtagaat
     5761 acctcgcacc ggtactgttc aacaagaatt ctaccatcaa agtgctgttt gatacggcaa
     5821 cgggaggatt gataaaagtg gatagggaat aaaggaattc taattccgga ttgtcaactg
     5881 gataaatcca tccttacgca actgcattac gtaggcggtg acccggggaa tataattctc
     5941 ttcctcccca aagtgcctgg caagtagata gatgatttcg cgcacggtac gatgtccatc
     6001 tatcagattc cagacagctg taccgtgttc ttccagcctc acatggatgt caggagacat
     6061 ccccttcggc aataaaaaac gacgcatcca ttcgtattta aaccgtgggt aggcgagtac
     6121 ggcgcactca ccttcccatt cggttgttat atgtccacag cggaccggaa cagcgtccaa
     6181 cagacttact tttccttcgg gtatttccat catacggtat ccgcttttcc tattatttct
     6241 gaatattagg ctcttccagc ttataaccat acttcttgtc tgccttcttc agcagtagag
     6301 ccactataag ggacaagcag gcaataccgg taaaaatgca cataggcacc gtatagtcat
     6361 acatattcgt tccatctggt ttcttgccgg atatacaata ggcatcaagc acccacccta
     6421 tcaatgtagg aataccccaa agaccgatat tctggataaa gaaaatcaat gcgtatgccg
     6481 tacccaactg gcttaccggg aatatcttgg ccacagccgg ccacatggca gaaggtacca
     6541 gcgagaaagc gatacccaaa attatcatca gcacaatagc taccagccaa tagtttatat
     6601 cgggaatagc ataaatgaaa tgcacacata tcagcatggc cgagcccagc agcatgatag
     6661 atgcggactt gccccgcttg tcaatgaaac caccaaagac cggagtcaga atcagcgctc
     6721 ccaatgccgg aagtccggca aatgtaccgg ccacattctc attgataccg tatttgataa
     6781 tcatcaactc ggaagcaaac ttctggaatg ggaatacaca agagtagaac aatacacaca
     6841 gcaatgctat cagccagaaa ccgggattga ccagaatatt cttcacatcc ttaaaagaga
     6901 acttctcttc ctcatcttcc gtaccggcag caatggcagc agcttccatc tgtttgtcca
     6961 gcttcttgtc catcactgca aagacgaaga aagcaatcat accgcccaac aacagaacca
     7021 aacccaacaa caccggtgtg gaaataccga aagcgcgggc caaaggaatg gctacggcat
     7081 aaccggcttg cgaaccgata cgtgctaaag cgacttgtac ccccatagcc gtggcaagct
     7141 ctttcccctt aaaccacttg gctatgattt tggaaactgt aataccggcg acctccgctc
     7201 ctactccaaa aatggaataa ccggcaaaag caacaaacac acccgtttta tagccaaata
     7261 tttcattgat tccgaataaa gtcgcgtcgg caccggcaag tcccgtcatt gcatagtatt
     7321 caagtgctgt accacctacc atcaggatag ttgccagctt tccggtgaaa cggataccaa
     7381 agcggtcgag gattaatcct ccccaaatca acatcaggaa aaaaacattc agaaaactat
     7441 aaccaccggt aaagaatccg aaatcggtac tcgaccaagc caagtccgtt tccaacattg
     7501 tcttcaacgg tgctaccacg tcgtttacat aataagctgc catcatcgtg aaggcaacaa
     7561 tcaccaatgc cccccaacgg gtagccttgg aatcattcaa tttaagtttg agttgttctg
     7621 tcattgtact atttggattt caatttatta atcagattgc ataaattgct gacaaaggta
     7681 aataaatact tcatcaaaac gaaaaaaggc tgacaccttt tcagtatcaa cctttctctt
     7741 atttttccaa gcgggagtca tccgcaatat ccttatctta ttctgctgca ggggcttctg
     7801 ctgcaggagc aggagtttca gccggagttg tagctgcagg ggcctccgat tgcggagctt
     7861 ctgtacctac gggcatgtta taaggattag ttttttcttc ttgttgcgcc tgttccagaa
     7921 tcacatcacc gcccttgcct gtggaagaag gaatagtgta agcagaaaca atactgaaga
     7981 ctaccatgac agctgccaga gtccaggttg ctttttccaa aaagtccgta gtcttgcgca
     8041 cacccataat ttggttggat gatgaaaagc ctgatgccag accacctcct ttagaatttt
     8101 gaatcaatac aatgaagcac atcagcacag atgcaatcag cattaagata actaataata
     8161 aatacatttt gttattttga tttagcgtta ataatcaatt tctccaaaaa tctgatttgg
     8221 tctgcaaagt aagcattttt ttttggataa ttcaaactta attttttaat aatttcaagc
     8281 gccttgtcat atcggtgctg ttttatatag attttggcta aagtttccgt aaaacagcta
     8341 tcgtccaact cttccgttac cggcgatacg gagggttctt cctcttcttc agtctcttcc
     8401 tccttctcta caagaaactc ccttctcgta tccgaggcat ccgaagactc actcttttgg
     8461 ataaagtcat ctatcaattc atgcccgcgc agtttaggca cttccgactc atcttctgca
     8521 tccacaccgg gttcttcctg cattaaatag gccgtataat ccaccgcata atccagctcc
     8581 gtatgctgtg aatgctcttc gggaacagta gccagaaatg cgtcaatcaa ggaaagggta
     8641 cggtccacac tcggctcttt ctccaaatcg ccggaaaaca gcgacgagac cttccgggat
     8701 ttcaaagtat agcggtcacc ctctataaag taaaacagca cacgacggtc tgccacatac
     8761 aacacagcct tgcgcaactc cgcgccaaag ttgatgtcgt gcagcagata gaggtttttc
     8821 agatagagca aacggagcga ctggaaataa ggatagcgtg ccaccaatgt gcgaagctcg
     8881 tacaaagtat ccctattcag cgtctcggga tgctgaatcc attgttgcaa atgggtaggc
     8941 gtcatgagtt taccagttag ctacagttgc attgaaaatc tgttcggcaa tgtctttcac
     9001 catcaaggtt atcagctggt cctgcacttc ggtcagcaat tttgaggaat cataggtctg
     9061 gaaagccgag aactgctgtt caaagtcctc ctcatggttc gtgttattgg tgtaacgcac
     9121 gttgacagtc agcgtcacct tcaccttcga agagtagccg ctggcatcca ccgattcatt
     9181 atattgattg tagccggtta tttctccgtc tatttccagg tctcctccgg aattcaccag
     9241 ttgcaggcga gtctgctgaa tgaacatatc cttcattttc tggttaaatt ctgttgccag
     9301 cggtgcatat acatactctg cccggttctg gaaatcggca atggaaatcg tttttacctt
     9361 tgtatagtcg atagagctta tcggagcaag tcccaacttc atactacatg aattcaccag
     9421 aaataacaag cttaccaaca aggaagcaaa tgccgctttt ttaatccaat ccatattctt
     9481 ttatctttct gtataacgta cgctcagaga tattcaaatc ctgagccgca ctcttacgct
     9541 tgccgtgatg tttttcaagc gccttacgta tcatttcttt ctccacttca tccagggaga
     9601 gtgactcctc cacatattct tccgtatcct ggaaatcatc gtccaccgga gtaaccggct
     9661 ttgccgaagg atgtataatg gtggggacac tggatgttac cggaggtacc accgccggag
     9721 tagccggcgt atagtaggcc gatgtggcaa ccgccggatt ggctaccgtt cccctttcag
     9781 ccataatctc atgcaccaac tttttcaagt ccgttacatc ctggcgcata tcaaacagaa
     9841 cctggtagag aatttcccgt tcactcccaa agctcttgtc ctccttcact ccaaacaagg
     9901 caggcaggcg ctgcatattg ttctgctcag gcagatagcc cttcagtatg gatgcattga
     9961 tttcacgatt ggtctcaatg atggatatct gctcggtgat attcttcaac tggcgcacat
    10021 tacccggcca tgagtagccc agcaacactt gcttgccgtc ttccgtcagc tgaatggcag
    10081 gcatacggta cttttctgca aagtccgaag caaactttcg gaacagcagc accacgtctt
    10141 caccgcgttc gcgcaatgga gggacctgaa taggaactgt gttcaaacgg taatacaagt
    10201 cttcacgaaa acgtccgtca gcaatggctt gtgtcaagtt tacattggta gcggcaacaa
    10261 tacgcacatc ggtcttttcc accttagaag aacctacttt gatgaattca ccgctctcga
    10321 gcacacgcaa caagcgtgcc tgggtaggca aaggcaattc gccgacttca tcaaggaaga
    10381 ttgttccgcc gttggcctca ccgaaatacc ccttccgttc gccgatagcc ccggtaaatg
    10441 cgcccttctc atgaccgaac agttccgagt caatcgtccc ttcgggaatg gctccacagt
    10501 tcacggcaat gtactgtcca tgcttgcgcc ggctgtactg gtgtattatc tgcggaaagc
    10561 tctcctttcc cacaccactc tctccggtaa tcagtacaga caagtcggtg ggcgctacct
    10621 ggatagcgat atcaatggca cgcatcagcg cttcattgtt gccgataatg ccgaaacgta
    10681 attttacttg ttgtatttcc gcttttgtca ttctacaaat cttcttctac actatcgagt
    10741 ttcagtttgt cgctatcgtc acgtttctcg taatattgct tgcgcagcgg atttgcatgt
    10801 gcctctttct cacgctggcg gttacggaac acatctattg ccacatagat agcctgccgg
    10861 aatgaatctt cagaggcgat tcctttcccg gcaatatcgt aggccgtgcc atgagcaggc
    10921 gaagtgcgta tcaccggcaa gccggcagta tagttcacgc cctcgtccat agccaatgcc
    10981 ttgaacggtg ccagcccctg gtcgtgatac atggccagga taccatcaaa atgggtaaag
    11041 ttatctgagc ccataaaccc gtctgccgga taaggaccat agcaaagcat acccttagca
    11101 gccatttcgt tgatggccgg aatgataatc tcctgctctt cagttcccag caatccgccg
    11161 tctcctgcat gcggattcag cgaaagcact gcaatacgcg gtgcgctgat agcaaaatcc
    11221 tgcttcaagg agcggttgaa tatcttcagt ttttcttgta tcagttcttt ggtgatgctt
    11281 ccggctatct ctttaacggg aatatgtccg gtcaccaatg ctacccggaa gtcatctttc
    11341 atcagaatca taagggcctt ctcgccatct cccaattttt gctctatata ctccgtatgt
    11401 ccggggaagg caaactcctc cgactggatg gtatgcttgt tgatgggagc tgtgacaatc
    11461 acgtctatca ttccctcctt atattcctca atggcttttt ccagtgcacc aagtgcagct
    11521 ttaccagctt caacgtcagg tttagagaac tcaaccttta cttcatcatc cgtacagttc
    11581 actacactca agcgattggg aaccgcttcg gaggcagagt tgacgatact gaaattggta
    11641 gacaagtcca atgatttacg atgataagct gccactttag gcgaaccgta gataatcggc
    11701 gtacacaatt ccagcatcac cgggtctgca aacgtcttta aaatcacttc ataccctaca
    11761 ccattaatgt cgccttgtgt aatgccgact cttattttgt tgtcttccat ttttattact
    11821 tattattagt agtatctttt gcggttacgc ctaccggaat ttccgcacct tccagcttgc
    11881 tgccaggcag tttcaaggta tagagcgaag cctccatctg acgtaccaga ttacgtttca
    11941 ttttatcagg tgaataaata aatatttcag atacgataat acgctgattg gctttgtcca
    12001 aacgtacatg cgatacgaac ggaccgccca tgaagtcacc ctttatgcgc cacaagccgc
    12061 gggcctccaa tgcatagtct ccctgcacac tgatagggcg tacatcggtc atcagagaat
    12121 ccgtcgacat atacatgcct tcacgggcac cagggatgtt agccttcatc acggaatcgc
    12181 gtttatgaac aaaatattct ttagtaaacg tatccttatc cgtataagga taagagtaga
    12241 ttacaaagtt ctggtcgccg gtagctgcat tcgtacctgc ccagaagaag ttctccccct
    12301 ccttggtaga tgtcagttcg cccggcaccc atacatcgca atcgaacagg cttttcacct
    12361 tcgttgctat atagtcgcta tgcttgtcct tcaatactga aatctgacga ttcatttccg
    12421 catgagtaaa gaaatcgatg attacctgcc tattctcctc cacaaatttc tcgaacgaag
    12481 cctcgtccgg cgcctggata gtgagaatgg actgaggagc agcatataca ttccttgcat
    12541 acttgaattt aggctgggta tagaggtctt tgttcacatc gacaataatg atattgcgaa
    12601 tcagttttaa agtggcatca taattggaag gggcagtata catgattcgg aatgaacgtt
    12661 ctgactgggg aagccccgga acatcagaat caagcacatc gaaaagcgcc ctaccggcag
    12721 gacgttccca caagccgggc tccaccacta ccagaacttc atacgcacga ccactggagg
    12781 tcggagtaaa cacacccttt ttaccaccac cgcaagcgga aaaaagtgtc agtacgagaa
    12841 ccatacttaa ataaaacaag tgctttctca tatctctatc attttagttt ttcacaaagc
    12901 tacgaagaat gcgtaatatc ctccctacct aagttaataa tttatattaa ttcttcttta
    12961 ttctcctcct gcttggcagt ggacaacatg ccacaagcgg caaatatatc ctctccacgc
    13021 gatgaccgta tagtggtaaa cagaccgtgc gaagtcagat aatcacggaa cgcagtcatg
    13081 gtttccatat cagccccttc aagattcact ccaggtatgg catgaaaacg aatcaggtta
    13141 atccggcagt ccagcccgcg tagcagcttc agaagttcct ttgcatacgg taacgagtca
    13201 ttcactcctt tgaaaacaat atattcaaaa gatagtctgc gctgtttgct aaaatcatag
    13261 tttcttaaca attccacaat ctccgtgatg gagaacgcct tctctgccgg catcagttcg
    13321 cggcgttgca aaggtatcgg cgaatgaagg ctgatagcca gatggcagtc cgattcctca
    13381 ataaaacgct gcaatccctt cttcaatccc acagaagaaa gtgtaacacg cttgggactc
    13441 cacgcatacc cataagaggc ggtcattatt tccagcgctt tcaatacctc gtccagatta
    13501 tcaagtggtt cacccatgcc catcattacc acattggtaa gcttgtccct ttcgggcaac
    13561 gaattaattt gattaataat ctggttggat gtcagattgg cagtaaaacc ttgtttgccg
    13621 gtcatacaga acttgcaatt catcttacag cccacctgag aggagacaca aagcgtagcc
    13681 cggtcttcgt cgggtatata gacagcttcc acgaaatgcc cctcgcctgc ccggtacaag
    13741 tatttcaccg taccgtctac agagcgcatg gcatctaccg gcgcttcggc acctacctca
    13801 tagatttctt tcagcaattc ccgatgcttc aacgaaagat tgctcatttc gtctatagaa
    13861 gtcaccttct tgtcatacag ccaggaagct atctgcttgg cagagaaacc gggcattccc
    13921 agattcttca ccacattctg caattcagag agcgtcaagc ccaatagagg tcgtttctgc
    13981 atatcgtttt tcattaaaac aaaactcttt caagaatgca aaggtaggaa taaagttgca
    14041 caaagacaac ggagagtgta gaaaatgaaa tgtacagaca atgaaaaagc cgcccggaag
    14101 taccggacgg cttttcaata tgggttttct attcttagaa gaataaataa cgttggtctt
    14161 ttacgttggc tttcagatac aagtcactga tgaactggct tgccatacgt gcatgcatgt
    14221 tagccaagtt agcctcttca gtttccttgt tgaatgtttc gttcagcttc tcttttgcat
    14281 aaggttgcag aacgaataca ccaccgttac ccttgatagg agcactcagc ttgttcactt
    14341 cggcaataga agcgtatgcg cctaccaaag gttcgctgct acgcaatgcc gggatatagg
    14401 caggagcaga gaaagtaacg tgctttacag aatcactgac agcatttgcc atattcttgt
    14461 actgctcgaa cgaagttgca ttggcagcct tcatatcagc cataatcttc tctgctttct
    14521 tgtcacggag aatttcagct ttcaactggt cctttaccaa agccagtggg cgataacctt
    14581 caggaacaat acttgcaaca cctactacca gcatacggtc gctctcgcca cattcgtaca
    14641 aaccggaaac ttcaccggct tttgcctcaa acgcccattt caaagcatct ttggttcctc
    14701 tgataccacc gataccatgt tcagagctgt acaagtcggc tctatccagc aacttgtaac
    14761 cggcatcttc cgcattggca atcattttct ctaaagtatt gtttgcagcg atgaactggc
    14821 taaactcatt gtatgccttg ctgtaagttt ccttgctgaa ttctaccgga cgcttgataa
    14881 cggctacctt atatttatcc ttgacagcct tcttgttggt tacttgcaaa atgacatttg
    14941 cttgtcccaa cgccagattg gtcagttcgt tctgtcccaa agttgtgaca gcggtaatgt
    15001 atttcaagtt gtcaccgtca atctgtgcgc cttcgtagtt agcagaagaa atccaggtag
    15061 gctcaccggt ctgaccgtac ttcttcgcaa cttcagcaaa gctggcacca cccttaatag
    15121 cattgtagat gctgtcggcc aaaatcttcg tcttttcagc atcttcggca actacctgaa
    15181 tctgacggaa ctcgatagag tccggcatgg cagcagtagc caatttcttg aaagagttga
    15241 gggtattgtc agatacgtta taataaggcc cgaacacacc acccaccgca acagagtcca
    15301 aacgggctgt cacatcagca ggcagagact tagtagtgta gaacaagtct gtataaggag
    15361 cttcggaacc ggtagaacgg ataaaggtag tatagtcaga aggattggca gtaagttgtt
    15421 cggtgtattc ttccatttcc ttctggagag cagctctgtc ttctgcactt gcagtaactt
    15481 gcacatcaat gaacttgata ttgcgagttt ccacatattg cttgaactgt tctttcttct
    15541 tgtcgtatgc agccttcaaa tcagaatcct tgataacgat ggtagagtca acgatagaag
    15601 aatagggaac tgcagcaagc agcaggtctg actgctctac tcttgcatca aaagcgtcct
    15661 gagcttctac cgggttggag aaaagggatt ttgtaatcaa agcttgatac ttctcctgaa
    15721 gacgtgcctg gataagggac ttttcgagga aagaccagaa cttgtacatg gattcatagt
    15781 attctgcata ttgtgaaggc atctgtgcct tattcatttt tgaatagtcc accaagaact
    15841 tcttcaacat atccttatca aacgcaccgg tctgaggatt acggaacgga gtctgttgca
    15901 gcatcggatg cacaccggca ttaatgatag cctgaatctc agccttcgat acaaccagac
    15961 cgagtttctt tgcttccttt tcaatcagct tattattgac gtatgttctc catacttcat
    16021 ctttgatttg gtttgtctgc tcatcgctca atgcactgtt gccactggag aacttgatga
    16081 cttctgtata ttcttctacc aatgcttgaa aatcctgagc ggaaattgat tccccgttca
    16141 cttcacctac gtcttgtgac tggtgtggct gaagcacttt ccacgcgtca cctgcgatga
    16201 aagcaaacag
//
