LOCUS       c00357_gnlPro..        12614 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OOEINPMA_357.
ACCESSION   c00357_gnlPro..
VERSION     c00357_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 01:23:29
            Original ID  :: gnl|Prokka|OOEINPMA_357
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12614
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12614
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2757:5713]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2758..5713
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..12614
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12614
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(2..283)
                     /locus_tag="ctg357_1"
                     /transl_table=11
                     /translation="MDGVITKQSEEYIGMMEMLKKCSKEIFAIQDLPVPVANEVYMTGE
                     QVCAMLHISSRTLQKLRDEKGIAYTAIGGKFLYPLSKLQLLLEENYRSY"
     CDS             618..1376
                     /locus_tag="ctg357_2"
                     /transl_table=11
                     /translation="MKRHNYNIAIAITISCILFFINGYHNYIKDKRKDNLEKYKAGYYD
                     NVTVKNKNIEPSTTKNYVPPKNWTKYIIANAFSISVPPTVELRKSNDSYTKDIKNLNWH
                     GHKINSNNVVFQQKGLSVNTPEAHQTYCRIIIDIQKGSLGEYPKFSDYEDLTIEDIHTF
                     QELAKQNSYEYKILGQPEVRWIKIEDTYGIEVEYVRNGANNSRTHVCNYYFFNDNLFAT
                     IILSYRQDDIRKWETDFSNIIKTFKWNNKK"
     CDS             1380..2039
                     /locus_tag="ctg357_3"
                     /transl_table=11
                     /translation="MEKISFMRRLSSSLIDKVLILVLFIISALCISPYGMASHLGSYYA
                     LLDAVPSSYPAQDTYKAMHSVYDNTIYESTEKWVQCYKEISQKPELIAPHKGETLSWDL
                     QITGLFIIVNFIYYLLWEWIFRASLGKFLCGLTVASDNNQPTTEKEIIKRCFLLLLLMI
                     AAVGLRFTFDINYYMTILLFFLIVDTSVIIKGKSLIDIMTNTYITKRKIYKNENLK"
     CDS             2758..4986
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg357_4"
                     /sec_met_domain="Gly_radical (E-value: 5e-47, bitscore:
                     148.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1170.3, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFTNGLWNKEINVSDFVSKNIAPYTGDASFLQGPTERTKR
                     IWDICLKALEEERNNNGVRSLDNTTVSTITSHKAGYIDKDNELIVGLQTDELLKRSIKP
                     FGGINVVAKACRENGVEVDDKVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGIDRLIEAKQEDLHNLTGPMTEARIRLREEVAEQIKALKDIK
                     VMGEYYGLDLSHPATSAQEAVQWVYMAYLAAIKEQDGAAMSLGNVSSFLDIFIEYDLAH
                     GKINETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTEAIGGRFNDGRVKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKDFCAKVSVDTSSIQYENDNLMREVRNC
                     DDYGIACCVSYQAIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKGIPVLTGETL
                     KFEEVMANYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMAFIDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAKVTARRNEIGLTEGFDTEGSFPCFGNNDDRVDHLGVDLVYYFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGPTPEERVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLEDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             4988..5713
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 75.5;
                     E-value: 1.7e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg357_5"
                     /sec_met_domain="Radical_SAM (E-value: 1.3e-31, bitscore:
                     99.5, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCPFRCLYCANPDTIDVKGG
                     TPTTPEEILQMAISQKAFFGKKGGITFSGGEPTLQAEALIPLFKELKANGIHICLDSNG
                     GIWNEKVEELFSLTDLVLLDIKQFNPERHRTLTGRSNEQTLRTAAWLEEHEHPFWLRYV
                     LVPGYSDSEEDTRLLGESLGKYQQIQRVEILPYHRLGVHKYEAMGWDYKLKEVKENTPE
                     QLERAEKLFKEYFTNVITN"
     CDS             complement(5782..7986)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 84.6; E-value: 1.3e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg357_6"
                     /sec_met_domain="Fn3-like (E-value: 1.8e-27, bitscore:
                     84.6, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 3.3e-75, bitscore:
                     242.6, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 6.7e-53,
                     bitscore: 168.9, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIILMVCLWGLGNTFTSAQTTEKEKFISSLMKQMTLDEKIGQ
                     LAQCTYRGNFTGPDGGNIPKEEYVRQGRIGSMLNVIGVKDIRRYQELALQSRLRIPLIF
                     GLDVIHGYRTGFPLPLAEAASFDLAMIEEAARYNALESAADGLNWVFAPMVDISWDARW
                     GRVMEGAGEDPYYGSRVAEARVRGLQGDDLADTTTVMACMKHFAGYGAPIAGKEYNSVD
                     MSMGHFANFYMPPYKAAIKVGAATVMSAFNDFNNIPCTANDFLLNRLLREQWGFKGFVV
                     SDYNSVEELVNHRYAVDKKDAAAKALNAGLDMEMVSTCYLTYLKELVQEGKVKESVLDD
                     AVRRILEKKYELGLFEDPFRYCNPERAARILNAPEVRNASLRMAERSVVLLENRESVLP
                     LTAQTRKIALIGGLSKSQYDMAGAWAATTDRNKVVTLYDALVRKGLEVSYAEGYDMKSN
                     QLTGLQEALQAAEASDVIVVAVGERFGQSGEKASKVNIAIPEGQQKLVSELAKTGKPVI
                     ALVMCGRPVIFNEIREHADAVLCTWWLGSEAGNAICNVLWGEYNPSAKLPMTFPAHVGQ
                     IPIYYQNKSTGRPTALKQTYKASYIDASTEPAYPFGYGLSYTDFGYSDLKLLPGKAAGV
                     HTEVSVKVTNTGKCAGEEVVQLYVQDKVASVTRPIKELKGFRKIHLNVGESKTVAFQIT
                     DDALGFYDNEMNYMVEPGDFVFMVGGSSDDVQQITYNLKE"
     CDS             complement(8017..10479)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 80.1; E-value: 3.4e-25)"
                     /gene_kind="other"
                     /locus_tag="ctg357_7"
                     /sec_met_domain="Fn3-like (E-value: 4.9e-26, bitscore:
                     80.1, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 5.1e-57, bitscore:
                     182.8, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 3.3e-51,
                     bitscore: 163.4, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKKKVALSGLLLCCAITAKAQVCITPQVEQRARELVSQMTLEE
                     KIDYISGPKSFYIRAVPRLGIPEIRMADGPQGIRNNTQSTLYPCGILSASTWNRKLARE
                     LGHGLARDAKARGVSILLGPGVNIYRSPLCGRNYEYFGEDPYLTGETAKEYILGVQEEG
                     VMATVKHFAANNQEWSRHHASSDVDERTLQEIYFPAFRKAVQEAGVGAVMDSYNPLNGV
                     HATENSWLNIDVLRKQWGFKGILMSDWTSVYSGVGAANGGLDLEMPVGKFMTREILIPA
                     IENGIVKEETIDAKVRHILQTLIAFGALDTPREDKSIDKDNAQSKEIALDLAREGVVLL
                     KNDNGTLPYRNGRTLVIGPNADIIPTGGGSGFVTPYSVVSLYDGMVQLKGGRQIELLSD
                     SILYKDMSQQIYTDGSFTQNGFKGEYYNTRNLTGELFQAAIEPAIDHAWKYGAPFDGMP
                     VDQFSARWTGVYKADKDGTVKFQLAGDDGYRLFVNDKLITGDWGNHSFSTRSAFMQVSA
                     GEIYRLRIEYFDNVGEATVSFQAGMMDEERLASSLKHARNVIVCAGFNSSTEGEGFDRP
                     FALSYGQEYLINKVASLHDNVAVVVNAGGGIDFRNWGQSVQAILMAWYPGQEGGKALAE
                     IITGKLSPSGKLPVSIEEKWEDNPVYGNYYDNRNVPHKRVQYAEGVFVGYRGYDRNGKQ
                     PLYPFGYGLSYSSFEYSNLSVEKTGGSRVTVSFDIKNTGKMDAAEAAQVYVRDVECSVP
                     RPLKELKGYDKVYLKKGETKRVRILLDEEAFAYYDVESHRFVVEKGTFEILAGPSSADL
                     PLKATVVL"
     CDS             complement(10656..11969)
                     /locus_tag="ctg357_8"
                     /transl_table=11
                     /translation="MEDELWLKKIKDKLEDYSEPLPVAGWERLEKELSVSGAPITGPHR
                     MIPFRRWAVAAAAVLLVAVSSVSLWLLQSPVGNEMRHTSVPALAVAPDVLPEQTVPAIR
                     TNSIEPAYRAHGNASAPNKEASHPLVAQHIRISVGEEQQEEMLPVETADEVVGIGQQAE
                     EPVVEDTDHETTMQTEEPETREDRYRPSGRDKLHLPEKNSSGRDAKGWAVGLSVGNTGG
                     FSLANEGEANVMSDYMPGSPIYGGNVDLSSTANGIVTIPDGQELVFKDGMPYLQRREKK
                     IADIDHKQPLSFGVSVRKNLAKGFSVESGLTYTYLASDVRYEGSSEKISQKLHYIGIPV
                     RANWNFVDAKNFTMYVSAGGAIEKCVYGKIGTESETVKPVQLSVMGAVGAQYNISNRVG
                     LYVEPGVSYFFDDGSSIQTIRKENPCNFTLQAGIRLTY"
     CDS             complement(11982..12614)
                     /locus_tag="ctg357_9"
                     /transl_table=11
                     /translation="LAITNLQRKFDKLLFFYLFIWVGNFRERMEEQELAERCRQGDNLA
                     RKELYERYAGRMLSVCLRYAGDRETAQDLMHDGFLKLFDSFDKFTWRGEGSLRAWMERV
                     MVNTVLQYLRKNDVMNQSSALENAPEAYEEPEGSSIDVIPQKVLMQFISELPAGYRTVF
                     NLYIFEEKSHKEIARLLGINEKSSASQLTRAKATLAAKVREWMKRND"
ORIGIN
        1 cataacttct ataattttct tccaataaca attgcaattt tgaaagagga taaagaaact
       61 taccacctat ggcagtataa gctatcccct tttcatcacg caacttttgc aaggttctgc
      121 tcgatatatg caacatggca catacttgtt caccagtcat atagacctca ttggctacag
      181 gaacaggcaa atcctgaatt gcaaaaatct ccttggagca tttcttgagc atctccatca
      241 tcccgatata ctcttctgac tgttttgtaa ttaccccatc catatcctat ttgccttttt
      301 gagttaatat cctagccaga tcactttcct tgtacacata ttttccacct atgaaagaac
      361 acggaataat gccatattcc ctataacttt gcaaactccg cttggaaata ttcagcacca
      421 gacagacttc ttgggcatta cccaaaggtt ataatagact tctcattgtt tttgcttgtc
      481 ttattattgt ttataccgta catgaatatc ctgaaaaggt taacactttt ttcttcacgc
      541 tgctagttga gattattact tatatagcta ctatatggat ttatcgtgga tttaaagaat
      601 taccctaaaa taaaaatatg aaaagacata attataatat tgcaatagct atcacaatta
      661 gttgtattct tttttttatt aatggttacc ataactatat aaaagataaa agaaaagata
      721 acttagaaaa atataaagcc ggatactatg acaatgtaac ggtcaaaaac aaaaatatag
      781 aacctagtac aacaaaaaac tatgttcctc ccaagaattg gactaaatac ataatagcaa
      841 atgctttttc tattagtgta cctcctactg ttgaactaag aaaaagtaat gattcataca
      901 ctaaagatat taaaaatctg aattggcatg gacacaaaat aaatagcaat aatgttgttt
      961 ttcaacagaa agggttatct gttaataccc ccgaagcgca tcaaacatat tgccgaatta
     1021 taatagatat ccaaaaagga agtctaggag aataccctaa attttcagat tacgaagatt
     1081 tgactataga agacatccat acatttcaag aactagcaaa acagaactct tatgaatata
     1141 aaattttagg tcaaccagaa gtgcgctgga ttaagattga agatacttac ggaatagaag
     1201 ttgaatatgt gcgaaatgga gcaaacaatt cccgtactca cgtctgcaat tattatttct
     1261 ttaatgacaa tctatttgca acaataatat tatcatatag acaagatgat ataagaaaat
     1321 gggaaacaga tttttcaaat ataattaaaa catttaagtg gaataataaa aaatgagtta
     1381 tggaaaaaat tagttttatg cgaagattat caagttcttt aatagacaaa gtcttaatcc
     1441 tggtattatt tattattagt gctttatgta tatctcccta cggaatggct tctcatttag
     1501 gaagttatta cgccctatta gatgcagtcc catcatctta tcccgctcag gatacatata
     1561 aagcaatgca tagtgtttat gacaatacta tttatgaaag tacagaaaaa tgggttcaat
     1621 gttataaaga aatatcacag aagcctgaat taatagctcc acataagggt gaaaccctat
     1681 cttgggattt acaaataacg gggcttttta taattgtaaa ttttatatat tatcttttat
     1741 gggaatggat atttcgcgca tcactaggca aatttctatg tggacttact gttgcttccg
     1801 ataataatca accaacaaca gaaaaagaaa ttatcaaacg ctgtttctta ttactactct
     1861 taatgatagc cgcagtaggt ctaagattta ctttcgacat caattattac atgactattt
     1921 tattgttttt cctgattgta gacacatctg taatcataaa agggaaatca ttaattgata
     1981 ttatgactaa cacatatatc acaaaaagaa aaatctataa aaacgaaaat cttaaataaa
     2041 acaaaacacc cagttttaca ttatagggtg taaaactggg tgtaaatctt ataaaccgct
     2101 aattatcaag gtttattgcg gagagacagg gattcgaacc ccgggtgcct cgcagcacaa
     2161 cggttttcaa gaccgccgca atcgaccact ctgccacctc tccaaaactt ctttttcaga
     2221 agtgcttttc ttttaaagcg gtgcaaagat acaaatcatt ttttattcta caaacttttc
     2281 tgcacaaaaa cagagcaatt ataccaaaat tcttgtttat acccactacg gaacgaacat
     2341 aacggcattt aggctatttg ttgaaattta tcaagggcaa gacagagttt tataacttac
     2401 tggctatcag tatatttaca aagagccaca ttcagtatac gattgaaccc tattcagtat
     2461 acgactgaat ggcattcact atacgactga attaggttca gaatacgact gttccttaaa
     2521 cctacatcat ttgtaaataa tgcagattat tattcggttc ttgtttcaat tcataaacca
     2581 catataaaga aagtattaac atctctactc ccccggacat tcactaccta ataatagtta
     2641 ttttatgctg ttcaacataa aaagagaagt atctcttata aaattacgga atttattcag
     2701 tatttttgcg cgctctaaag gataacatta tctaacctac taacaaaaac aaattttatg
     2761 gaattgaaca aaacctttac caatgggctt tggaataaag aaatcaatgt cagtgatttc
     2821 gtcagtaaaa acatcgcacc ctataccggg gatgcatctt tcttgcaggg acctaccgaa
     2881 cgtaccaaac gtatctggga catctgtctg aaggctctcg aagaagaaag gaacaacaat
     2941 ggcgtccgtt cactggacaa taccaccgta tctaccatca cttctcataa agccgggtat
     3001 attgataagg acaatgaact tattgtcggt ttgcagactg atgaactgtt gaaacgatcc
     3061 atcaaacctt tcggaggcat caacgtggta gcaaaagcat gccgtgaaaa cggagtggaa
     3121 gtggacgata aagtaaaaga catcttcacc cattaccgca aaacacataa cgacggcgta
     3181 ttcgatgtat ataccgaaga aatccgttcc ttccgctcac tgggattcct taccggattg
     3241 cccgacaact atgcccgcgg acgtatcatc ggcgactacc gccgattggc tctctacggc
     3301 atcgaccgtc tgattgaagc caagcaggag gacttgcaca acctcaccgg cccgatgacc
     3361 gaagcacgca tccgtctacg cgaagaagtg gcagaacaaa tcaaagcttt gaaggacatc
     3421 aaggttatgg gcgaatatta cggactcgac ctcagccatc cggctacatc agctcaagag
     3481 gccgtgcaat gggtatacat ggcatatctt gctgccatca aagagcagga cggagcagcc
     3541 atgtcactgg gtaacgtatc ttcgttcctc gatatattca ttgaatacga tctggctcac
     3601 ggaaaaatca atgagacgtt tgcacaggaa ctgatagacc agttcgtcat caagctgcgc
     3661 atggtacgcc atctgcgtat gcaatcatac aatgatatct ttgccggtga cccgacttgg
     3721 gtgaccgaag ccatcggagg acgcttcaat gacggacgcg tgaaggtcac caagacttct
     3781 ttccgctttt tgcagacgct atacaacctc ggtccttctc cggaaccgaa cttgaccgta
     3841 ttgtggagtc ccgaactgcc ggaaggcttc aaggatttct gcgccaaagt ttctgtagat
     3901 accagctcca tccagtacga aaacgacaac ctgatgcgtg aagtgcgcaa ctgcgacgac
     3961 tacggcatcg cctgctgtgt atcctaccaa gccatcggca aacaaatcca gttcttcggc
     4021 gcacgtgcca accttgccaa ggccctgctg ctcgccatca acggtggacg ttgcgaaaat
     4081 accggaactg tcatggtgaa aggtattccc gtattgaccg gtgagacatt gaagtttgag
     4141 gaagttatgg ccaactacaa gaaggtactg actgaaatag cccgtgtcta caacgaggcc
     4201 atgaatatca tccactacat gcatgataag tattattatg agaaagccca gatggcattc
     4261 atcgataccg acccacgcat caatctggca tacggtgttg ccggcctttc catcgccata
     4321 gactcactgt ccgccatcaa atatgccaaa gtcactgcac gccgcaacga aatcggcctg
     4381 accgaaggtt tcgacactga aggttcattc ccctgcttcg gcaataatga cgaccgtgtg
     4441 gaccacctgg gagtagacct cgtttactat ttcagcgaag aactgaaaaa gctgcctgtc
     4501 tacaagaatg cccgtcccac cctttccttg ctgactatca cctccaacgt gatgtacggc
     4561 aagaagaccg gtgccactcc ggacggacgc gccaaaggtg ttgcctttgc tccgggtgcc
     4621 aacccaatgc acggacgtga caagaacggt gccatcgctt ccttgagctc cgtagccaaa
     4681 ttgcgctacc gcgactcgca ggacggcatc agcaatacgt tctccattgt tcccaaatca
     4741 ctgggcccga caccggaaga acgtgtagag aacctggtaa ccatgatgga cggctacttc
     4801 accaaaggtg cccaccattt gaacgtaaac gtactgaacc gcgaaatgct ggaagatgcc
     4861 atggaacatc ctgaaaagta tccgcaactc accatccgcg tttccggcta tgccgtgaac
     4921 ttcgtgaagt tgagccgcga gcatcagttg gaagtcatca gccgttcatt ccacgaaaga
     4981 atgtaatatg ataaatgtac actcctacga aagtatggga acattcgacg ggccgggtct
     5041 ccggctcgtc gttttcctgc aaggatgtcc gttccgttgt ctgtattgtg ccaatccgga
     5101 tacgattgat gtaaaaggag gcactcccac cactccggaa gagattctgc aaatggctat
     5161 cagccaaaag gcattcttcg ggaagaaagg aggtattact ttctccggcg gtgagcctac
     5221 cctgcaagca gaagcgctga ttcctctttt caaggagctg aaggcgaacg gcatccatat
     5281 ctgtctggac agtaacggag gcatctggaa tgaaaaggtg gaagagctct ttagcctgac
     5341 tgacctcgtg ctgctggaca tcaagcaatt caatcccgaa cgccaccgta cgctgacggg
     5401 acgaagcaac gaacagacac tccgcaccgc tgcctggctc gaagaacatg aacacccctt
     5461 ctggctgcgc tatgtactgg tccccggtta cagcgattcg gaagaagaca cccgcctgct
     5521 gggtgaaagt cttggcaaat accagcagat acaacgggtg gaaatacttc cttatcaccg
     5581 tctgggtgtt cacaaatacg aagccatggg atgggattac aaattgaaag aagtgaagga
     5641 aaatactccg gaacaactgg aacgggcaga aaaactgttc aaagagtatt tcacgaatgt
     5701 gataaccaac taaaacagaa aagcaaggct gtccggatat gattccagac agccttgctt
     5761 ttcatttata gggtaagaat cctattcttt caagttatag gtaatctgct gtacatcatc
     5821 actactgcca cccaccataa agacgaaatc accaggttct accatataat tcatctcatt
     5881 gtcatagaat cccagtgcat cgtcagttat ctgaaaagct acagttttgc tttcacccac
     5941 attcagatga attttcctga agcccttcaa ttcctttatc ggacgcgtaa cagaggctac
     6001 cttatcctgc acatacaatt gaactacttc ctctcctgca cacttaccgg tattagtcac
     6061 ttttaccgac acctccgtat ggacgcctgc agccttgccc ggcagcagtt tcaaatcaga
     6121 atatccaaaa tccgtgtacg aaagcccata tccgaaagga taggcaggct cagtggaagc
     6181 atcgatataa gatgccttat aggtctgttt caatgcggta gggcggccgg tgctcttatt
     6241 ctgataataa atgggaatct gtcctacgtg tgcaggaaat gtcatgggca atttagccga
     6301 aggattatac tctccccaca acacattgca tatggcattg ccggcctcac ttcccagcca
     6361 ccaagtacac agtaccgcat cagcatgttc ccttatctca ttgaagatta ccggacgccc
     6421 acacatgaca agagcaatga caggttttcc agtctttgcc agttccgaca ccagcttctg
     6481 ctgcccctcg ggtatggcta tattcacttt ggaagccttc tcgccactct gaccgaatct
     6541 ctcgcctacc gccacaacaa tgacatccga agcctcagca gcctgtaatg cttcctgcaa
     6601 tccggtcaac tgattgctct tcatatcata gccttcagca tagctcacct ccagtccttt
     6661 ccggaccaat gcatcatata aggtcaccac tttgttccgg tccgtagtgg cagcccaagc
     6721 acctgccata tcgtactggg attttgagag tcctcctatc aaggctatct tcctcgtctg
     6781 tgccgtcaac ggaagcacag attccctatt ctccagcaat acaacggaac gctcggccat
     6841 acggagcgaa gcattacgga cttcgggcgc attgagtatt ctggccgctc tttccggatt
     6901 acagtagcga aaagggtcct caaacaatcc caactcatat ttcttctcca atatacgccg
     6961 tactgcatca tcaagcacac tctcctttac tttcccttct tgaacaagct ccttcagata
     7021 agtcaagtag caggtactta ccatctccat gtccagacca gcattcagcg ctttggctgc
     7081 ggcatctttc ttgtcaacag cataacggtg gttcaccaat tcctctaccg aattataatc
     7141 ggacacaaca aatcccttaa atccccactg ctctctcaat agccggttga gcaagaaatc
     7201 attggcagta caaggaatat tattaaaatc attgaaagca ctcatcacgg tagctgctcc
     7261 tacctttatg gccgccttat agggaggcat ataaaaattg gcaaagtggc ccattgacat
     7321 atccacacta ttatactcct ttcctgctat cggtgcacca tatccggcaa aatgtttcat
     7381 acatgccatg acagtcgtcg tgtctgccaa atcgtctcct tgcaagcctc tgacacgcgc
     7441 ctccgctacc cgagaaccat aataagggtc ctcaccggcc ccttccatga cgcgtcccca
     7501 acgtgcgtcc cacgaaatat ccaccatcgg ggcaaaaacc cagttcaaac catcagcggc
     7561 actttccaaa gcattgtagc gtgcagcttc ctcaatcatg gccaaatcga aacttgcagc
     7621 ctcggcaagc ggaagcggaa atccggtacg atagccgtgg ataacatcca gtccgaaaat
     7681 taaaggaatg cgcaaacgcg attgcaaagc aagctcttga taacggcgta tatcctttac
     7741 tcctatcaca ttcagcatag agcctattct gccttgccgg acatactctt ctttaggaat
     7801 atttccaccg tcgggtccgg taaaattccc tcggtaggtg cattgtgcaa gctggcctat
     7861 cttttcatcc agcgtcatct gcttcatcaa gcttgagatg aatttctcct tctccgtagt
     7921 ttgtgccgag gtaaaggtgt taccaagtcc ccacagacaa accatcagta ttattatctt
     7981 tttcatactg ccattcttgt tttgatattt attttatcat aaaacaacag ttgccttcaa
     8041 tggtaaatca gctgaagaag gacctgccag aatctcaaaa gtcccctttt ccactacaaa
     8101 ccgatgtgat tccacatcat agtaggcaaa ggcttcctca tccagcaata tccgaacgcg
     8161 cttggtttca cccttcttca agtaaacctt atcgtagcct ttcaactcct tcaatggacg
     8221 cggaacagaa cattccacat cccgcacata tacctgagcc gcttccgcag catccatctt
     8281 tccggtattc ttgatgtcaa agcttaccgt aacccggctt ccccccgtct tctcaacact
     8341 cagattacta tattcaaaac tactgtatga cagtccatac ccgaaaggat agagcggctg
     8401 ctttccgttc cggtcatatc ccctataacc tacgaaaaca ccttcggcat actgcacccg
     8461 tttatgaggt acattgcgat tgtcataata attaccatat accggattat cttcccattt
     8521 ttcctcgatg ctgactggta gtttgccact tggcgaaagc ttgcccgtaa tgatttcggc
     8581 aagggccttt ccaccctcct gccccggata ccatgccatc aaaatagctt gtacactctg
     8641 cccccaattg cggaaatcta ttccacctcc ggcattcacc accacagcca cattatcatg
     8701 aagtgaagcc actttattaa tgagatattc ctgcccgtat gacaatgcaa acggacggtc
     8761 gaacccttca ccttctgtac tgctgttgaa cccggcacat acaataacat tcctggcatg
     8821 cttcagtgaa gaggccaaac gctcctcatc catcattcct gcctggaaac tgacagtcgc
     8881 ctcacccaca ttatcaaaat attcaatacg caaccggtat atctcccctg cactgacctg
     8941 cataaatgca ctgcgggtac tgaatgaatg gttcccccaa tctccggtaa tcagcttatc
     9001 gtttacaaac agacggtatc cgtcatcgcc agccagctgg aacttgacag ttccatcctt
     9061 gtcagccttg taaactcccg tccaacgggc agaaaactga tctaccggca tgccgtcgaa
     9121 cggtgcaccg tatttccagg catggtctat ggcaggctct atggcagctt gaaagagttc
     9181 tccggtaaga ttacgagtat tataatattc gcccttaaaa ccgttttgcg taaaactgcc
     9241 atccgtataa atctgttggg acatatcctt ataaagaatg ctgtcagaca gcagctctat
     9301 ctgtctgccg cccttcaact gaaccatacc gtcatagagt gacactaccg aataaggggt
     9361 gacaaatccg cttcctcctc ctgtgggaat aatatcggca ttaggcccga ttaccaatgt
     9421 tctaccgttc cggtaaggca acgtaccgtt atcatttttc aataagacta ctccttctct
     9481 cgccaagtca agtgcaattt ccttagactg tgcattgtct ttatcgatag atttatcttc
     9541 tctcggagta tcaagtgctc caaaagcaat caatgtctgg agtatatgcc ggactttggc
     9601 gtcaatggtc tcttccttca cgataccatt ctctattgcc ggaataagaa tttccctggt
     9661 catgaattta ccgacgggca tttccaaatc caaccctcca ttagcggctc ccacaccaga
     9721 atatacagat gtccagtcag acatcaggat acctttaaat ccccactgct tgcgtaatac
     9781 atcaatgttc agccagctgt tttcggtggc atgtaccccg ttcagcggat tatagctatc
     9841 cataaccgcc cctactcctg cttcctgcac agcttttcgg aacgcgggaa aataaatttc
     9901 ctgcagcgtg cgttcatcca catctgagct ggcatgatgt ctgctccact cctggttatt
     9961 ggccgcaaaa tgcttcaccg tagccataac tccctcttcc tgcactccca agatatattc
    10021 tttagcagtt tcgcccgtca aataagggtc ttcaccaaaa tactcatagt ttcgcccgca
    10081 tagaggagag cggtagatat tgactccagg ccccaacaga atacttaccc cacgggcctt
    10141 tgcatcccgg gccaaaccat gtcccagctc tctagccaac ttacggttcc atgtcgaagc
    10201 cgacaagatg ccacaaggat acaaggtact ttgagtattg ttacgtatgc cttgcggacc
    10261 atcggccatc ctgatttcgg gtatgccaag ccggggtaca gcccggatat aaaaagattt
    10321 gggaccggaa atgtaatcga ttttttcttc cagcgtcatt tgagaaacca actccctggc
    10381 acgctgctcc acctggggag taatacacac ttgtgctttt gccgtgattg cacaacaaag
    10441 caatagcccg cttaaggcta ctttcttttt aatcttcatt ttgtctattt tactacgtgt
    10501 ttgttatatt gccgggcatg tcccgaccta ctttctttct tctcaatcaa taaaaaaccg
    10561 tgtcccttca tccaccaacg aagaaacacg gccgaaagtt attaagaaaa ttctgaatct
    10621 acaagaaagt ggacaaaaac atgtctgtcc tgctatcaat aagtaagacg tataccggcc
    10681 tgcaacgtaa agttacacgg gttctccttg cgtatagtct gtatcgacga accgtcatca
    10741 aagaaataag atactcccgg ttccacatac aggcccaccc tattgcttat gttatactgg
    10801 gcaccgacag cacccatgac agaaagctgt accggtttca cagtctcact ctcagtacca
    10861 atcttgccat acacacattt ttcaatggca ccccccgccg aaacgtacat cgtaaagttc
    10921 tttgcatcca caaagttcca gttggcccgt accggaatgc caatataatg cagcttctgg
    10981 cttatctttt ccgagctgcc ctcatacctt acgtcagaag caagataggt atacgtcagc
    11041 ccgctttcca cagagaaacc cttcgccaag tttttccgca ccgaaacacc gaaactgagc
    11101 ggttgtttat ggtctatatc cgcaattttc ttttcgcgtc tttgcagata gggcatacca
    11161 tccttaaaaa ccagttcctg cccgtcggga atagtaacaa tgccattggc cgtagaggat
    11221 aaatctacgt taccgccata aataggactt ccaggcatgt agtccgacat cacattcgct
    11281 tccccttcat tcgccaatga aaaacctccc gtatttccta cggacaagcc aaccgcccat
    11341 cctttagcat ccctaccaga actgtttttt tccggaagat gcagtttgtc ccggcctgac
    11401 ggacgatagc ggtcttccct tgtctccggt tcctcggtct gcattgtagt ttcatggtcc
    11461 gtatcttcca ctaccggttc ttccgcctgc tgtccaatac cgacaacctc atctgcagtt
    11521 tcaaccggca gcatttcctc ctgctgttct tcgccaaccg atattctgat atgttgtgca
    11581 accaaagggt gacttgcctc cttattgggc gccgatgcat ttccatgtgc ccgataagca
    11641 ggctctatgg aattagtccg tatggcaggt actgtctgtt ccggcaagac gtccggagcc
    11701 acagccaaag cgggcactga cgtatgccgc atttcattcc ctaccggact ctgcaacagc
    11761 cacagactga cggacgaaac cgccaccagc aacacagctg ccgcggccac cgcccagcga
    11821 cggaaaggta tcatcctatg cggtccggtt atcggagctc cggaaacgga caattccttc
    11881 tccaaccgct cccatccggc aaccggcagc ggttcggaat agtcttccag cttgtccttt
    11941 atctttttca accacaattc atcttccata cgttccttca tttaatcatt tcttttcatc
    12001 cactcacgta cttttgccgc taaagtcgct ttagcacgcg tcaactgcga ggcagaggat
    12061 ttttcattaa ttcccaatag tcgagcaatc tccttatggg atttctcttc aaaaatatat
    12121 aagttgaata cggtacgata gccggcaggc aattcactga taaactgcat tagtaccttt
    12181 tgaggaatga catctattga cgaaccttcc ggttcctcat aagcttcagg tgcattctcc
    12241 aaggccgatg actgattcat cacatcattt ttccgcaaat actgcaacac cgtattcacc
    12301 attacgcgtt ccatccatgc ccgcagagaa ccctctcccc gccaagtgaa cttatcgaaa
    12361 gaatcaaaaa gtttcagaaa accgtcatgc atcaggtctt gggcagtctc ccggtcacct
    12421 gcataacgaa ggcatacgct gagcatgcgt cccgcatagc gctcatacag ttctttgcgg
    12481 gcaagattgt ctccttgcct acagcgttct gccaattcct gttcttccat tctctctcta
    12541 aagtttccca cccaaataaa tagatagaaa aataacagtt tgtcgaattt tctttgtaaa
    12601 ttagtaatcg ctaa
//
