LOCUS       c00777_gnlPro..        15896 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CJDNIIFN_777.
ACCESSION   c00777_gnlPro..
VERSION     c00777_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 22:57:45
            Original ID  :: gnl|Prokka|CJDNIIFN_777
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15896
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15896
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2940:5896]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2941..5896
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15896
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15896
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             2..637
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 83.1; E-value: 3.9e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg777_1"
                     /sec_met_domain="Fn3-like (E-value: 1.4e-26, bitscore:
                     83.1, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 9e-25, bitscore:
                     78.4, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="RNWGQSVQAMLMAWYPGQEGGKALAEIITGKLSPSGKLPVSIEEK
                     WEDNPVYGNYYDNRNVPHKRVQYAEGVFVGYRGYDRNGKQPLYPFGYGLSYSSFEYSNL
                     SVEKTGGSRVTVSFDIKNTGKMDAAEAAQVYVRDVECSVPRPLKELKGYDKVYLKKGET
                     KRVRILLDEEAFAYYDVESHRFVVEKGTFEILAGPSSADLPLKATVVL"
     CDS             767..2872
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 84.7; E-value: 1.2e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg777_2"
                     /sec_met_domain="Fn3-like (E-value: 4.4e-27, bitscore:
                     84.7, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 2.7e-74, bitscore:
                     240.9, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 1.6e-52,
                     bitscore: 169.0, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQMTLDEKIGQLAQCTYRGNFTGPDGGNIPKEEYVRQGRIGSML
                     NVIGVKDIRRYQELALQSRLRIPLIFGLDVIHGYRTGFPLPLAEAASFDLAMIEEAACY
                     NALESAADGLNWVFAPMVDISWDARWGRVMEGAGEDPYYGSRVAEARVRGLQGDDLADT
                     TTVMACMKHFAGYGAPIAGKEYNSVDMSMGHFANFYMPPYKAAIKVGAATVMSAFNDFN
                     NIPCTANDFLLNRLLREQWGFKGFVVSDYNSVEELVNHRYAVDKKDAAAKALNAGLDME
                     MVSTCYLTYLKELVQEGKVKESVLDDAVRRILEKKYELGLFEDPFRYCNPERAARILNA
                     PEVRNASLRMAERSVVLLENRESVLPLTAQTRKIALIGGLSKSQYDMAGAWAATTDRNK
                     VVTLYDALVRKGLEVSYAEGYDMKSNQLTGLQEALQAAEASDVIVVAVGERFGQSGEKA
                     SKVNIAIPEGQQKLVSELAKTGKPVIALVMCGRPVIFNEIREHADAVLCTWWLGSEAGN
                     AICNVLWGEYNPSAKLPMTFPAHVGQIPIYYQNKSTGRPTALKQTYKASYIDASTEPAY
                     PFGYGLSYTDFGYSDLKLLPGKAAGVHTEVSVKVTNTGKCAGEEVVQLYVQDKVASVTR
                     PIKELKGFRKIHLNVGESKTVAFQITDDALGFYDNEMNYMVEPGDFVFMVGGSSDDVQQ
                     ITYNLKE"
     CDS             complement(2941..3501)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg777_3"
                     /sec_met_domain="Radical_SAM (E-value: 1.4e-20, bitscore:
                     64.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAISQKAFFGKKGGITFSGGEPTLQAEALIPLFKELKANGIHICL
                     DSNGGIWNEKVEELFSLTDLVLLDIKQFNPERHRTLTGRSNEQTLRTAAWLEEHEHPFW
                     LRYVLVPGYSDSEEDTRLLGESLGKYQQIQRVEILPYHRLGVHKYEAMGWDYKLKEVKE
                     NTPEQLERAEKLFKEYFTNVITN"
     CDS             complement(3668..5896)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg777_4"
                     /sec_met_domain="Gly_radical (E-value: 1.3e-46, bitscore:
                     148.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1172.6, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFTNGLWSKEINVSDFVSKNIAPYTGDASFLQGPTERTKR
                     IWDICLKALEEERNNNGVRSLDNTTVSTITSHKAGYIDKDNELIVGLQTDELLKRSIKP
                     FGGINVVAKACRENGVEVDDKVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGIDRLVEAKQEDLRNLTGPMTEARIRLREEVAEQIKALKDIK
                     VMGEYYGLDLSRPATSAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIFIEYDLAH
                     GKIDETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTEAIGGRFNDGRVKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKDFCAKVSVDTSSIQYENDNLMREVRNC
                     DDYGIACCVSYQAIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKGIPVLTGETL
                     KFEEVMANYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMAFIDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAKVTARRNEIGLTEGFDTEGSFPCFGNNDDRVDHLGVDLVYYFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGPTPEERVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLEDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             7014..7739
                     /gene_functions="resistance (resist) CfxA (Score: 527.2;
                     E-value: 7.9e-161)"
                     /gene_kind="resistance"
                     /locus_tag="ctg777_5"
                     /transl_table=11
                     /translation="MMSVFKVHQALALCNDFDNKGISLDTLVKIDRNRLDSKTWSPMMK
                     DYSELVISLTVRDLLRYTIAQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQIAYTE
                     EEMSADHDRAYFNYTSPLGAAMLMNRLFTESIVSGEKQSFIKNTLKECVTGTDRIVAPL
                     LDKERVSIAHKTGSGDVNENGILAAHNDVAYICLPNNVCYTLAIFVKDFKGNESQASQY
                     VAHISEVVYSLLIQNSAIP"
     CDS             complement(7843..8286)
                     /locus_tag="ctg777_6"
                     /transl_table=11
                     /translation="MQERHGKQIRNLQSIHNQELEAKDREISRLNTLLEKAFKWFPMLR
                     EMLRMEKLCAVIGFTKDMIDCLLTRKEAIQCNGKIYSEEHRRKFEIKNNIFKVEKNPTD
                     DSKLVLTINRQPISEWFKEQWEKLRQGLRQPTEEPRKSRGFKL"
     CDS             8593..9201
                     /locus_tag="ctg777_7"
                     /transl_table=11
                     /translation="MFLSGLGFRLPTLHGEDVRCQSLHFHHIVIIELLALARVVVHPVE
                     YDMGMIIRLKPLFTDLETLPIPGFGLSTKPVSLVLMQEDLERCNTPASLALLTKLSYIC
                     QCCIWSDEQYSLTDWRTSSHFYNLSILSLALTLLFLHRSSGLFLDHPFDAVIVRLQVRT
                     AEARVYPLLVIGSQFGYNVDSGLADIAHVLGSSPVMSPA"
     CDS             complement(9471..10028)
                     /locus_tag="ctg777_8"
                     /transl_table=11
                     /translation="MAKRECSEAHFTHNGKRYFAIAFPNVSGGYEIRNQYFKGCIAPKE
                     ISHIKQPGTARETCYVFEGFMDYLSFLTLRLENCPKYPELDRQDYMVLNSVANVSKAIY
                     PLGSYERIHCFFDNDRAGMEAMQQIYKEYGRDLYIRDASQTYSGCKDLNEYLQKQTERN
                     RQVQSAKGVRSQPPKKKNGFRL"
     CDS             complement(10642..11718)
                     /locus_tag="ctg777_9"
                     /transl_table=11
                     /translation="MDYMKDIKEISAEEAVILWQASRLSLSKIYEKAPEILKVQGSVIG
                     TLGNFSASIGKAKSKKTFNVSAIVAAALKNGTVLRYVAELPEEKRKILYVDTEQSPYHC
                     LKVMKRILRMAGLPDDRDNEHLEFLALRKYTPEQRIRIVEQAIYNTPDIGLVIIDGIRD
                     MVYDINSPGESTRIISKLMQWTDDRQIHIHTILHQNKGDENARGHIGTELNNKAETVLL
                     VEKDKSNGDISNVSAMHIRAMDFEPFSFRINDNAIPELLEGYKPETKKPGRPEEEKFDP
                     YRHITEQQHRIALEAVFGLKEEYGYKELEDTLIKTYVSVGVKLNHKKAVSLITMLRNKR
                     MIVQENGRKYTFMPDFHY"
     CDS             complement(12265..13302)
                     /locus_tag="ctg777_10"
                     /transl_table=11
                     /translation="MAGEINKLIPQYGELNRIYNDWVTNYAFSFDKQKFITDFYRQHND
                     TKAFEAAILELVLDKQKEQYTLILNSLKIEIEKNIRAYETKPLNDDVIKRVCFHYADRH
                     NSAIKDQLEITTKLHEPLNDAYHRYDFIGFREHTDEEEIQAEKEYERCKAEYDKEKKEL
                     DKLYELQKQDRKEAFQYIENLSGNVYRLSLLFMEVLKKYLPNDREEKQQDEPVKQNEQE
                     EVQNSPEGQHEYFDMKQLSPIHETCVGEQFEAITIADFYANINLYPCKNKLKIKAREKI
                     RVCYLIFLMSEKLSKQYRDEWRSQILKLLDIDESYYRSKYKEPVSDFPSDSNQKFAKEM
                     ESIFG"
     CDS             complement(13308..14468)
                     /locus_tag="ctg777_11"
                     /transl_table=11
                     /translation="MGNYILYHQNLQGWGSKIIKQLAKAIRFNYPEKKGYSERNLTYMC
                     QFARSYPLNVLRSFIDTDTRLSVPSIQNVTDEVLKLNNGQFTQELTAQIQSADCQSLEI
                     TQEVPAQIQDVEKTVSAIYRMEIREIEKVFLKSPVAKINWASQMVILNGSLPLGIGYWY
                     MKQAVEMGWSSNVLKMQIENNLYNRQINNNKVNNFTATLPAPQSDLANYLLKDPYIFDL
                     AGAKEKADERDIEEQLVKHVTRYLLEMGNGFAFVARQKHFQIGNSDFFADLILYSIPLH
                     AYIVVELKATPFKPEYAGQLNFYINVVDDKLRGKNDNKTIGLLLCKGKDEVVAQYALTG
                     YDQPIGISDYQLSKAIPENLKSALPSVEEVEEELASFLDKDNNPQN"
ORIGIN
        1 ccgcaattgg gggcagagtg tacaagctat gttgatggca tggtatccgg ggcaggaggg
       61 tggaaaggcc cttgccgaaa tcattacggg caagctttcg ccaagtggca aactaccagt
      121 cagcatcgag gaaaaatggg aagataatcc ggtatatggt aattattatg acaatcgcaa
      181 tgtacctcat aaacgggtgc agtatgccga aggtgttttc gtaggttata ggggatatga
      241 ccggaacgga aagcagccgc tctatccttt cgggtatgga ctgtcataca gtagttttga
      301 atatagtaat ctgagtgttg agaagacggg gggaagccgg gttacggtaa gctttgacat
      361 caagaatacc ggaaagatgg atgctgcgga agcggctcag gtatatgtgc gggatgtgga
      421 atgttctgtt ccgcgtccat tgaaggagtt gaaaggctac gataaggttt acttgaagaa
      481 gggtgaaacc aagcgcgttc ggatattgct ggatgaggaa gcctttgcct actatgatgt
      541 ggaatcacat cggtttgtag tggaaaaggg gacttttgag attctggcag gtccttcttc
      601 agctgattta ccattgaagg caactgttgt tttatgataa aataaatatc aaaacaagaa
      661 tggcagtatg aaaaagataa taatactgat ggtttgtctg tggggacttg gtaacacctt
      721 tacctcggca caaactacgg agaaggagaa attcatctca agcttgatga agcagatgac
      781 gctggatgaa aagataggcc agcttgcaca atgcacctac cgagggaatt ttaccggacc
      841 cgacggtgga aatattccta aagaagagta tgtccggcaa ggcagaatag gctctatgct
      901 gaatgtgata ggagtaaagg atatacgccg ttatcaagag cttgctttgc aatcgcgttt
      961 gcgcattcct ttaattttcg gactggatgt tatccacggc tatcgtaccg gatttccgct
     1021 tccgcttgcc gaggctgcaa gtttcgattt ggccatgatt gaggaagctg catgctacaa
     1081 tgctttggaa agtgccgccg atggtttgaa ctgggttttt gccccgatgg tggatatttc
     1141 gtgggacgca cgttggggac gcgtcatgga aggggccggt gaggaccctt attatggttc
     1201 tcgggtagcg gaggcgcgtg tcagaggctt gcaaggagac gatttggcag acacgacgac
     1261 tgtcatggca tgtatgaaac attttgccgg atatggtgca ccgatagcag gaaaggagta
     1321 taatagtgtg gatatgtcaa tgggccactt tgccaatttt tatatgcctc cctataaggc
     1381 ggccataaag gtaggagcag ctaccgtgat gagtgctttc aatgatttta ataatattcc
     1441 ttgtactgcc aatgatttct tgctcaaccg gctattgaga gagcagtggg gatttaaggg
     1501 atttgttgtg tccgattata attcggtaga ggaattggtg aaccaccgtt atgctgttga
     1561 caagaaagat gccgcagcca aagcgctgaa tgctggtctg gacatggaga tggtaagtac
     1621 ctgctacttg acttatctga aggagcttgt tcaagaaggg aaagtaaagg agagtgtgct
     1681 tgatgatgca gtacggcgta tattggagaa gaaatatgag ttgggattgt ttgaggaccc
     1741 ttttcgctac tgtaatccgg aaagagcggc cagaatactc aatgcgcccg aagtccgtaa
     1801 tgcttcgctc cgtatggccg agcgttccgt tgtattgctg gagaataggg aatctgtgct
     1861 tccgttgacg gcacagacga ggaagatagc cttgatagga ggactctcaa aatcccagta
     1921 cgatatggca ggtgcttggg ctgccactac ggaccggaac aaagtggtga ccttatatga
     1981 tgcattggtc cggaaaggac tggaggtgag ctatgctgaa ggctatgata tgaagagcaa
     2041 tcagttgacc ggattgcagg aagcattaca ggctgctgag gcttcggatg tcattgttgt
     2101 ggcggtaggc gagagattcg gtcagagtgg cgagaaggct tccaaagtga atatagccat
     2161 acccgagggg cagcagaagc tggtgtcgga actggcaaag actggaaaac ctgtcattgc
     2221 tcttgtcatg tgtgggcgtc cggtaatctt caatgagata agggaacatg ctgatgcggt
     2281 actgtgtact tggtggctgg gaagtgaggc cggcaatgcc atatgcaatg tgttgtgggg
     2341 agagtataat ccttcggcta aattgcccat gacatttcct gcacacgtag gacagattcc
     2401 catttattat cagaataaga gcaccggccg ccctaccgca ttgaaacaga cctataaggc
     2461 atcttatatc gatgcttcca ctgagcctgc ctatcctttc ggatatgggc tttcgtacac
     2521 ggattttgga tattctgatt tgaaactgct gccgggcaag gctgcaggcg tccatacgga
     2581 ggtgtcggta aaagtgacta ataccggtaa gtgtgcagga gaggaagtag ttcaattgta
     2641 tgtgcaggat aaggtagcct ctgttacgcg tccgataaag gaattgaagg gcttcaggaa
     2701 aattcatctg aatgtgggtg aaagcaaaac tgtagctttt cagataactg acgatgcact
     2761 gggattctat gacaatgaga tgaattatat ggtagaacct ggtgatttcg tctttatggt
     2821 gggtggcagt agtgatgatg tacagcagat tacctataac ttgaaagaat aggattctta
     2881 ccctataaat gaaaagcaag gctgtctgga atcatatccg gacagccttg cttttctgtt
     2941 ttagttggtt atcacattcg tgaaatactc tttgaacagt ttttctgccc gttccagttg
     3001 ttccggagta ttttccttca cttctttcaa tttgtaatcc catcccatgg cttcgtattt
     3061 gtgaacaccc agacggtgat aaggaagtat ttccacccgt tgtatctgct ggtatttgcc
     3121 aagactttca cccagcaggc gggtgtcttc ttccgaatcg ctgtaaccgg ggaccagtac
     3181 atagcgcagc cagaaggggt gttcatgttc ttcgagccag gcagcggtgc ggagtgtctg
     3241 ttcgttgctt cgtcccgtca gcgtacggtg gcgttcggga ttgaattgct tgatgtccag
     3301 cagcacgagg tcagtcagac taaagagctc ttccaccttt tcattccaga tgcctccgtt
     3361 actgtccaga cagatatgga tgccgttcgc cttcagctcc ttgaaaagag gaatcagcgc
     3421 ttctgcttgc agggtaggct caccgccgga gaaagtaata cctcctttct tcccgaagaa
     3481 tgccttttgg ctgatagcca tttgcagaat ctcttccgga gtggtgggag tgcctccttt
     3541 tacatcaatc gtatccggat tggcacaata cagacaacgg aacggacatc cttgcaggaa
     3601 aacgacgagc cggagacccg gcccgtcgaa tgttcccata ctttcgtagg agtgtacatt
     3661 tatcatatta cattctttcg tggaatgaac ggctgatgac ttccaactga tgctcgcggc
     3721 tcaacttcac gaagttcacg gcatagccgg aaacgcggat ggtgagttgc ggatactttt
     3781 caggatgttc catggcatct tccagcattt cgcggttcag tacgtttacg ttcaaatggt
     3841 gggcaccttt ggtgaagtag ccgtccatca tggttaccag gttctctaca cgttcttccg
     3901 gtgtcgggcc cagtgatttg ggaacaatgg agaacgtatt gctgatgccg tcctgcgagt
     3961 cgcggtagcg caatttggct acggagctca aggaagcgat ggcaccgttc ttgtcacgtc
     4021 cgtgcattgg gttggcaccc ggagcaaagg caacaccttt ggcgcgtccg tccggagtgg
     4081 caccggtctt cttgccgtac atcacgttgg aggtgatagt cagcaaggaa agggtgggac
     4141 gggcattctt gtagacaggc agctttttca gttcttcgct gaaatagtaa acgaggtcta
     4201 ctcccaggtg gtccacacgg tcgtcattat tgccgaagca ggggaatgag ccttcggtgt
     4261 cgaaaccttc ggtcaggccg atttcgttgc ggcgtgcagt gactttggca tatttgatgg
     4321 cggacagtga gtctatggcg atggaaaggc cggcaacacc gtatgccaga ttgatgcgtg
     4381 ggtcggtatc gatgaatgcc atctgggctt tctcataata atacttatca tgcatgtagt
     4441 ggatgatatt catggcctcg ttgtagacac gggctatttc agtcagtacc ttcttgtagt
     4501 tggccataac ttcctcaaac ttcagtgtct cgccggtcaa tacgggaata cctttcacca
     4561 tgacagttcc ggtgttttcg caacggccac cgttgatggc aagcagcagg gccttggcaa
     4621 ggttggcacg tgcgccgaag aactggattt gcttgccgat ggcttggtag gatacacagc
     4681 aggcaatgcc gtaatcgtcg cagttgcgca cttcgcgcat caggttatcg ttctcgtatt
     4741 ggatagagct tgtgtctacg gaaactttgg cacagaaatc cttgaaacct tccggtagtt
     4801 ccgggctcca cagtaccgtc atgtttggtt cgggagaagg accgagattg tatagggttt
     4861 gcagaaaacg gaaagaggtt ttggtcactt tcacacgtcc gtcgttgaaa cggccgccaa
     4921 tggcttcggt cacccaagtc gggtctccgg caaagatgtc attgtatgac tgcatacgca
     4981 gatggcgtac catgcgcagc ttgatgacga actggtctat cagttcttgt gcaaaagttt
     5041 cgtcaatctt gccgtgagcc aaatcatact cgatgaagat gtcgaggaat gaagatacat
     5101 tgcccaatga catggcagca ccgtcttgtt ctttcacggc agccagataa gccatatata
     5161 cccattgcac agcttcttgc gctgatgttg cggggcggct gaggtcgagt ccgtagtatt
     5221 cgcccatcac tttgatgtct ttcagagcct tgatttgctc tgctacttct tcacgcagac
     5281 ggatacgggc ttcggtcatg ggacctgtca gattgcgcaa gtcttcttgc ttggcttcga
     5341 caagtcggtc gatgccgtag agtgccagac gacggtagtc accgatgata cgtccgcgag
     5401 catagttgtc gggaagaccg gtcaggaatc ccaatgaacg gaaggaacgg atttcttcgg
     5461 tatatacatc gaatacgccg tcgttatgtg ttttgcggta atgggtgaag atgtctttta
     5521 ctttatcgtc cacttccact ccgttttcac ggcatgcttt tgctaccacg ttgattcctc
     5581 cgaaaggttt gatggatcgt ttcaacagtt cgtcagtctg caaaccgaca ataagttcat
     5641 tgtctttatc aatatacccg gctttatgag aagtgatggt agatacggtg gtgttgtcca
     5701 gtgaacggac gccattgttg tttctttctt cttcgagagc cttcagacag atgtcccaga
     5761 tacgtttggt acgttcggta ggtccctgca ggaaagatgc atctccggta tagggtgcga
     5821 tgtttttact gacgaaatca ctgacattga tttctttgct ccaaagcccg ttggtaaagg
     5881 ttttgttcaa ttccataaaa tttgtttttg ttagtaggtt agataatgtt atcctttaga
     5941 gcgcgcaaaa atactgaata aattccgtaa ttttataaga gatacttctc tttttatgtt
     6001 gaacagcata aaataactat tattaggtag tgaatgtccg ggggagtaga gatgttaata
     6061 ctttctttat atgtggttta tgaattgaaa caagaaccga ataataatct gcattattta
     6121 caaatgatgt aggtttaagg aacagtcgta ttctgaacct aattcagtcg tatagtgaat
     6181 gccattcagt cgtatactga atagggttca atcgtatact gaatgtggct ctttgtaaat
     6241 atactgatag ccagtaagtt ataaaactct gtcttgccct tgataaattt caacaaatag
     6301 cctaaatgcc gttatgttcg ttccgtagtg ggtataaaca agaattttgg tataattgct
     6361 ctgtttttgt gcagaaaagt ttgtagaata aaaaatgatt tgtatctttg caccgcttta
     6421 aaagaaaagt acttctgaaa aagaagtttt ggagaggtgg cagagtggtc gattgcggcg
     6481 gtcttgaaaa ccgttgtgct gcgaggcacc cggggttcga atccctgtct ctccgcaata
     6541 aacgctgaaa atcagcaaat tataaaacaa acacccaatt ttatacccaa gaatgtaaag
     6601 ttgggtgttt ttattttatt taagacgaat catattcgct cggaaaataa tttgataaaa
     6661 aacagaacaa acgaaaaaaa caaccaattc attttccgta agatttcgta tctttgcagt
     6721 aaataataaa tcagggtctg tcatgataat atataatgtt taaaaatcgt agtatgaaaa
     6781 aaagtagaag aaaacgcctt gtaattttgt gtatagcttt agtttgtatc atagttttag
     6841 tttttttatt gttctctaaa tcaacttcta ataatagtac aaatccacct ttgacagatg
     6901 ttttgactga tagcatttct cggatagtat cagcttgtcc tggtgaaatt ggagtggcaa
     6961 ttattattaa taacacagat acagttaaag ttaatgataa gagtgtatat cctatgatga
     7021 gtgtatttaa ggttcatcag gcattagctc tttgcaatga ttttgataac aaagggattt
     7081 cacttgatac cttagtaaag atagatagga atagacttga ttcaaagact tggagtccta
     7141 tgatgaaaga ttattccgag ttggttatat cattaaccgt gagagattta cttcgttata
     7201 ctattgctca aagtgataat aatgcaagca atctgatgtt taaagatatg gtcaatgttg
     7261 ctcaaactga cagttttata gccacactta ttcctcgttc aagttttcag atagcttata
     7321 cagaagagga aatgtcggct gaccacgata gggcttactt taattataca tctcctcttg
     7381 gtgccgcaat gttgatgaac cgtttgttta ccgaaagtat tgtcagtggt gagaagcaaa
     7441 gtttcattaa gaatacatta aaagaatgtg tgacaggtac agatagaata gtcgctccgc
     7501 ttcttgataa agaaagggtt tctattgcac ataagacggg ttctggtgat gtcaatgaaa
     7561 atggtattct tgcagctcac aatgatgttg cctatatatg cctgcctaat aatgtctgct
     7621 atactttagc gatatttgtt aaggatttca agggtaatga atcacaagca tcacaatatg
     7681 ttgcgcatat atcagaggtc gtatattctt tattaataca aaattcggca attccttaag
     7741 ttgcgtttac tttgaagctt caatggtaaa cattatataa tttatacaat ataaaagcac
     7801 ttcgtaacta tcagagtgct tttatattgt cttttttttc tattataact tgaatcctct
     7861 actttttctt ggttcttccg ttggttgtcg caaaccttgc cgaagtttct cccattgctc
     7921 tttgaaccat tcgcttatcg gttgcctgtt tatggtcagt acaagtttgc tatcatcggt
     7981 cggattcttc tccaccttga agatgttgtt tttgatttca aactttcttc tatgttcctc
     8041 ggaataaatc ttgccattac attggatagc ttctttcctt gtcaaaagac aatctatcat
     8101 atctttggta aatccaatga cagcgcagag tttttccatt ctcaacattt ctctaagcat
     8161 cggaaaccac ttgaatgcct tttcaagcag agtgttcaat cgtgatattt ccctgtcttt
     8221 ggcttcaagt tcttggttgt gtatgctctg aagattgcgt atctgtttgc catgtcgctc
     8281 ttgcatttcc tgcatttgga ttttgagggt gtcaatacct ttgtctcgtt tggcaatctc
     8341 ttggtgcaaa tcttcattag ttcgctccag ctctttcatc tttccacttc cgaaaagaga
     8401 accaactccg cttgctatgg cggtggctgc attggtggct gttttcttta gcttgtcagt
     8461 gcgtatttct gatttcacct gtttcagttc ctgttcagca agacctatct gttcttcttt
     8521 gtgccgtttt gcagcatcca tgcgttgcag ttcggctctc tgcttttcaa tgatgaaatc
     8581 atttcgttcc aaatgttcct ttccggtctc ggatttagat tgcccacgtt gcatggagag
     8641 gatgtcagat gccaaagtct gcatttccat catatcgtca tcattgagct tttggctctt
     8701 gcccgtgtcg tggttcatcc agtcgaatac gatatgggca tgataattcg gcttaaacca
     8761 cttttcaccg acttggaaac tctccctatc cccggttttg ggttgtccac taagccagtg
     8821 tccctcgtcc ttatgcagga agatttggag cggtgtaata ccccagcgtc tctggcactc
     8881 ctcaccaaac tttcgtacat ctgccagtgt tgtatctggt ctgatgagca atactccctc
     8941 acggattgga gaacatccag ccacttttat aatctttcca ttctttccct tgcgctcacg
     9001 ctccttttcc tgcatcgctc gtccggtctt ttccttgacc atccgtttga tgctgtcata
     9061 gtgcgcctgc aggtcaggac tgccgaagcc cgggtttatc cactgctcgt tattggaagt
     9121 cagttcgggt acaatgtaga ttctggactc gccgatattg cgcatgtact cggcagttct
     9181 ccggttatga gccccgcttg atgtcactct gcagggtttg atatgtatgc ttgattttgt
     9241 tgccatattc ttaaaatttg atttggattg ttgatgaaat cttctgttgt ccgctcataa
     9301 ccgcacaggg ttcttagggg tgcaacccat aagcggagat tgcaaagaga ggggcactct
     9361 ttgctcgggg ttcttagggg agaaacgccc tgagtgggtc attagggcaa agccctaatc
     9421 ccctcgggag agcccacaac tacgaaagcg aagcgtgtag ttatagtggg ctataaccga
     9481 aagccgtttt tctttttcgg tggttggctg cgcacccctt ttgcagattg aacttgcctg
     9541 tttctttcag tctgtttctg taagtattcg ttcaagtcct tgcatccgct gtatgtctgc
     9601 gaagcgtcac ggatgtataa gtccctgccg tattccttat agatttgctg catggcttcc
     9661 attcctgcac ggtcattgtc aaagaaacag tggatgcgct catagcttcc caacggatag
     9721 attgctttgg aaacattggc tactgagttc aacaccatat aatcttgcct gtccagttcg
     9781 ggatatttcg ggcaattctc caatctcaaa gtaagaaatg aaagatagtc cataaatccc
     9841 tcaaacacat aacatgtttc cctcgctgtt cccggctgtt tgatatgaga aatctctttc
     9901 ggtgcgatgc atcccttgaa atactggttg cggatttcat acccacccga cacattggga
     9961 aaggcgatgg cgaaataccg tttgccatta tgggtgaagt gcgcttcact gcattctctt
    10021 ttcgccattg caatgtttat tcccctttcc tgcaaataag caagcagggc aggagaagaa
    10081 agcggtacaa tctccagttg ttgaaaactt ggctcggaag atgattgctt gccaaaagaa
    10141 aaagacacgg ggcgaatacg gggtgtctgt tcttcgattt tttgcaagag gtaaggcaca
    10201 tggtcggaac aataaagttc ctgtgccagt gcgatgatat tcccaccttt gccgagtgca
    10261 aaatcatacc attggttacg ttctgtattt accttgaacg atgcttccgt ttcttccctt
    10321 agtggtgact tataccacag gtttatgccc tgttgtttga cgggtgaaaa tcctaaactg
    10381 tgcagataat ccgctatttt gatttgtttc gctgtctgta tatccataag acgataggtt
    10441 taatgatagt tgaattggtt tattttctct tttcgcccgt acctctttat gaagtacggt
    10501 ctgtataatc acttcacttt attttcgtat atatagagta cggtaataaa gtgaagcggt
    10561 tttgccacat ttcgcaacca cttcgcttta tccctaatat atagaccccc ggaataaagt
    10621 gaagcgattg caaggtgtgg gctaatagtg gaagtcgggc atgaacgtgt actttctgcc
    10681 gttctcctgc actatcattc gtttgttccg aagcatggtg atgagcgata ccgccttttt
    10741 gtggttcaac tttaccccca cagacacata agtcttaatt aaggtgtcct ccagttcctt
    10801 gtagccatat tcctctttca gcccgaaaac tgcttccaat gcgatgcggt gctgctgttc
    10861 ggtgatatgc ctgtaagggt cgaacttttc ctcttccggt cttcccggtt tcttggtttc
    10921 gggcttgtaa ccctccaaca gttcaggtat ggcattgtca ttgatgcgaa atgaaaaagg
    10981 ctcgaagtcc attgcccgta tgtgcatggc tgaaacattg cttatatctc cattgctctt
    11041 gtccttttcc acaagaagga cagtttcagc cttgttgttc agttccgtac cgatatgccc
    11101 ccttgcgttc tcatcgccct tgttttggtg gagtatcgtg tggatatgta tctgcctgtc
    11161 gtccgtccac tgcatcagct ttgatatgat gcgtgtcgat tcaccggggc tgttgatgtc
    11221 atataccatg tcacggatgc cgtctatgat tacaagccct atgtcaggcg tattgtaaat
    11281 agcctgctct acaatcctga tacgctgttc gggcgtgtat ttcctcaaag caagaaattc
    11341 cagatgctca ttgtccctgt catctggaag cccagccatc cgtaaaatac gtttcatgac
    11401 tttcagacaa tgataaggac tttgttccgt gtccacatac aggattttcc gtttctcttc
    11461 gggtagttcc gccacatatc ttagcactgt accattcttc aatgctgccg ccacgatagc
    11521 cgacacattg aaagtctttt tgcttttggc tttgccgatt gatgcactga aattacccag
    11581 tgtaccaatg accgaacctt gcacttttag aatctcaggt gctttctcat agattttcga
    11641 caggctcagg cgtgaggctt gccaaaggat tacggcttct tccgccgata tttcttttat
    11701 atctttcata taatccataa gtacacctcc cgttattttc gtcctccggt tttctttcca
    11761 gccagttcaa gggcaagttc cgcatccacg ataatcttgc gccctatttg cgtaatggct
    11821 ttgtctatct ttccgctttt ctttatacgg ttggcggtag gcagactgca cccgaacaat
    11881 ttggcaatgc caagtattcc gtacacatac tttctttctg tgtccgtaac gggctgtggc
    11941 tgcgcttccg tttggttgga agcgtacttg cttagaaata tgaactcttc gcctgtcatc
    12001 tgccagacgg gttttaataa taactcttga agatttgtca tcgtccaatc tatttagtcg
    12061 ttaaacaatc agccctgcgc actggctgtt atttctgttc tcgaacgatg caaaattagg
    12121 tatggctgta agtggtaagg atgtggataa tacaaatggg atactgcgct atctcattaa
    12181 atatcagaca ataaaaatac cactcaaaaa ttaatttgag tggtaaaagt ggtaatttcg
    12241 tagaatgtca ggttatatca cgaattatcc gaatatgctt tccatttcct ttgcgaattt
    12301 ctggttgctg tcactcggaa aatcggaaac aggttctttg tatttcgacc tgtaatagct
    12361 ctcgtcaata tccaacaatt ttaatatttg gcttctccat tcatccctgt attgcttgga
    12421 tagtttctcg ctcatcagga atatcaggta acacacccgt atcttttccc ttgccttgat
    12481 ttttagttta ttcttgcagg ggtacaggtt tatattggca tagaaatccg ctatggtaat
    12541 ggcttcgaac tgttccccga cacaggtttc atgaatgggc gaaagctgct tcatgtcaaa
    12601 atattcatgt tgtccctccg ggctattctg tacttcttct tgttcgtttt gcttgactgg
    12661 ttcatcctgc tgtttttctt ccctatcatt aggaaggtac ttttttagga cttccataaa
    12721 aagaagactt aggcggtaaa cattgccgga aaggttttct atatattgaa aagcctcttt
    12781 cctgtcttgc ttttgcagtt cataaagttt atccaattct ttcttttcct tgtcgtattc
    12841 agccttgcag cgttcatatt ccttttctgc ctgtatttct tcttcgtccg tatgctcccg
    12901 aaaaccaatg aaatcatatc tgtggtatgc gtcattcaaa ggctcgtgca acttggtggt
    12961 aatctccaac tggtctttaa ttgcagaatt atgcctgtct gcgtagtgaa aacacacacg
    13021 ctttatgacg tcatcattca gcggttttgt ttcataagcc cgtatatttt tttctatttc
    13081 gattttcaga ctattgagaa tcaatgtgta ttgttctttc tgcttgtcaa gtaccagttc
    13141 aaggatagcg gcttcaaaag cctttgtatc attgtgctgc ctgtaaaagt cggtgatgaa
    13201 tttctgcttg tcaaaagaaa aagcataatt ggttacccaa tcattatata ttctattgag
    13261 ttctccatat tggggaatca gtttgtttat ttctcctgcc atagacttca attttgggga
    13321 ttattgtcct tgtcaaggaa agatgccagt tcttcttcca cctcttccac acttggcaaa
    13381 gctgatttca agttttcggg tatagccttg ctcagttgat aatcgctgat gcctatcggt
    13441 tggtcgtagc ctgtcaatgc gtattgtgct accacctcat cttttccttt gcacagcaac
    13501 agcccgatag tcttgttgtc attttttccc ctcagtttgt catccaccac attgatgtag
    13561 aaattcagtt gccctgcata ctccggtttg aatggagtag ctttcagttc tacaacaatg
    13621 tatgcgtgta gcggaataga atatagaatc aagtcggcaa agaaatcact gttacctatt
    13681 tgaaaatgct tctgccgggc gacaaaggca aaaccattgc ccatttccaa caaataacgg
    13741 gtaacgtgct ttaccagctg ctcttctatg tccctttcgt ctgccttttc tttcgctcca
    13801 gccaaatcga agatgtacgg gtctttcaat aggtaattgg caaggtcgct ttgtggtgct
    13861 ggaagtgtgg ctgtgaaatt gtttaccttg ttgttgttga tttgtctgtt atataggttg
    13921 ttttcaattt gcattttcag cacattgcta ctccagccca tttctacagc ctgtttcata
    13981 taccaatatc ctatgcctaa cggtaacgaa ccgttaagta tgaccatttg gcttgcccag
    14041 tttattttgg caacagggga tttcaggaaa actttttcta tttccctaat ctccatcctg
    14101 taaatggcag aaactgtttt ctccacatcc tgaatttgcg caggaacttc ctgcgtaatt
    14161 tctaaagatt gacaatcagc ggattgtatt tgcgcagtaa gttcctgcgt aaattgtccg
    14221 ttgttcagtt tcaatacttc atctgtaaca ttctgtatgc ttggaacaga cagccttgtg
    14281 tctgtatcaa tgaaacttcg tagcacgttc aacggatatg accgtgcaaa ttggcacata
    14341 taagtaaggt tacgctccga ataacctttc ttttcggggt aattgaaccg gatagccttt
    14401 gccagttgct tgatgatttt gcttccccag ccttgcaagt tctgatgata caggatatag
    14461 ttgcccattt tccagtaatg gaacagcatt tgcgcattgg ctgcggcaat cagccggact
    14521 tgcgcctgtt ctatttccga accgacggca tgaacaaatg cgtcaaagtc cgttcttcct
    14581 atatgatatt ctctgttatt ttccattcta atgtttattg ttgtcgcaaa tataattcaa
    14641 atagctgata atctatgaaa ctgattgata cttttatagt tggttaaact tgttcatggc
    14701 atttgcctta atatcatccg ctatgtcaat atagggtttc atggctttat agtcactgtg
    14761 ccccgtccat ttcatcacga cttgtgccgg aataccgaga gccagcgcat tacagatgaa
    14821 tgttcttctt cctgcatggg tggttaataa tgcgtatttc ggggtgactt catctatacg
    14881 ttcatttcct ttataatatg tttcccgtac aggctcgttg atttcagcca gttcccccag
    14941 ttctttcaga taatcattca tcttctgatt gctgataaca ggcagtgcca tgtggttttc
    15001 aaaatggact tccttgtatt tttcgagtat ggttttactg tggtcgttca gttcaattat
    15061 caggctgtct gccgttttga ctgtggtaac ttcgatgtgg tcgggtttca catcgcttct
    15121 tttcagatta cgaacatctg aatatcgcag gcttgtgaag caacagaaca gaaaaacatc
    15181 cctgacacgt tccagatatt gtttgtcttt cggtatccga taatctttca gcctgttcaa
    15241 ttcgtcccaa gtcaggaata tcaccttttt agaggtggtt ttcaatttgg gcttgaaagt
    15301 gtcgtatgca atattctgat gatgcccttt cttgaagctc cagcgcagaa accatttgag
    15361 gaatcccatc tgtttgccga tggtgctgtt cctcatatcc tttttgtcac gcaggaaatt
    15421 tacatactcg ttcaagccga actcgttgaa gtattcaaag gttacatctt ccttgaactc
    15481 tttgaggtgg tttttcactg ctgagaattt ctcgtaggtg gatgccgtcc agttattctg
    15541 attgccacac tcctttacaa actcatcgaa tacttcccaa aaacttattt gtgtttcttc
    15601 ctgctgctct tcgctggtgt ctttcatccg caggttgaac gcatccttta gctgttgggt
    15661 ggtcggtatg gtttcctgta cctcaaactc cttgaacacg ttttgaatct cggcataata
    15721 tttcagcaag tccgcattga tttcggatgc gctttgtttt agtttgttgg tgcatccgtt
    15781 ctttacccgt tgtttgtcgg catcccattt ggctacgtca atccggtagc ctgttgtaaa
    15841 ctcgatgcgt tggcttgcgt atatgacacg catacggatg ggtacgttct ctacga
//
