LOCUS       c00025_gnlPro..        15356 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KMHMMEOI_25.
ACCESSION   c00025_gnlPro..
VERSION     c00025_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 01:26:12
            Original ID  :: gnl|Prokka|KMHMMEOI_25
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 22516
            Orig. end    :: 37872
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15356
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[32516:35472]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12956
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15356
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15356
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(1112..1384)
                     /locus_tag="ctg25_32"
                     /transl_table=11
                     /translation="MGHHHLGTYIPVFGVRSIALDGVELWKRLKAVLAEKAGFLAVIIG
                     NGCFTMPDTPIVTVPVSSTGHLSLECERRRRPIEGSGCILPDHPG"
     CDS             1475..2209
                     /locus_tag="ctg25_33"
                     /transl_table=11
                     /translation="MNHVLQGDAIKTAIESHRRQMPYNMGTLFWQHNDCWPVASWASRD
                     YYGRWKAQHYYTRKVYDDILISPVVEGDDLKVYAVSDRLENTSGRLQLQVCRFDGTVVY
                     HWDKSVGISGNDSRVCFSAPLAKLLEGADRGTVYVRVDYTDKSGRVYHNNYCLDKQKNM
                     NYPKVDLQTEVRSIEGGYEVTVSTDKFARAVCLSVADNESVYSDNYFDVQPKSSVQVQV
                     RTRLSAEAFNASLRLTCLNNEF"
     CDS             complement(2297..3001)
                     /locus_tag="ctg25_34"
                     /transl_table=11
                     /translation="MKKLRMTLATSMLLFLTAIVLQSCLDDWDDKYDTLFAVGTVKVIE
                     GKDYYFSLDEGSKLYPSDTTYVHDYAVTDGQRAFIYFRELEEKLPGYEYNAQIKHIENI
                     LTKDIYSMPAEKADSIGDDNINATDLWITGEYLNIKYQFYHSNNEDKKHMLNLVINEAS
                     TGENDKPDYVNLEFRHNAYNDSQLTLSTGLASFKLDNIAEQLKEKKGLNIRVKSLYDGE
                     RFMTIDIKKENN"
     CDS             3184..3732
                     /locus_tag="ctg25_35"
                     /transl_table=11
                     /translation="MEEQELAERCRQGDNLARKELYERYAGRMLSVCLRYAGDRETAQD
                     LMHDGFLKLFDSFDKFTWRGEGSLRAWMERVMVNTVLQYLRKNDVMNQSSALENAPEAY
                     EEPEGSSIDVIPQKVLMQFISELPAGYRTVFNLYIFEEKSHKEIARLLGINEKSSASQL
                     TRAKATLAAKVREWMKRND"
     CDS             3745..5058
                     /locus_tag="ctg25_36"
                     /transl_table=11
                     /translation="MEDELWLKKIKDKLEDYSEPLPVAGWERLEKELSVSGAPITGPHR
                     MIPFRRWAVAAAAVLLVAVSSVSLWLLQSPVGNEMRHTSVPALAVAPDVLPEQTVPAIR
                     TNSIEPAYRAHGNASAPNKEASHPLVAQHIRISVGEEQQEEMLPVETADEVVGIGQQAE
                     EPVVEDTDHETTMQTEEPETREDRYRPSGRDKLHLPEKNSSGRDAKGWAVGLSVGNTGG
                     FSLANEGEANVMSDYMPGSPIYGGNVDLSSTANGIVTIPDGQELVFKDGMPYLQRREKK
                     IADIDHKQPLSFGVSVRKNLAKGFSVESGLTYTYLASDVRYEGSSEKISQKLHYIGIPV
                     RANWNFVDAKNFTMYVSAGGAIEKCVYGKIGTESETVKPVQLSVMGAVGAQYNISNRVG
                     LYVEPGVSYFFDDGSSIQTIRKENPCNFTLQAGIRLTY"
     CDS             5598..7697
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 80.4; E-value: 2.7e-25)"
                     /gene_kind="other"
                     /locus_tag="ctg25_37"
                     /sec_met_domain="Fn3-like (E-value: 1.9e-25, bitscore:
                     80.4, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 1.6e-43, bitscore:
                     140.7, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 1.1e-50,
                     bitscore: 163.9, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LGPGVNIYRSPLCGRNYEYFGEDPYLTGETAKEYILGVQEEGVMA
                     TVKHFAANNQEWSRHHASSDVDERTLQEIYFPAFRKAVQEAGVGAVMDSYNPLNGVHAT
                     ENSWLNIDVLRKQWGFKGILMSDWTSVYSGVGAANGGLDLEMPVGKFMTREILIPAIEN
                     GIVKEETIDAKVRHILQTLIAFGALDTPREDKSIDKDNAQSKEIALDLAREGVVLLKND
                     NGTLPYRNGRTLVIGPNADIIPTGGGSGFVTPYSVVSLYDGMVQLKGGRQIELLSDSIL
                     YKDMSQQIYTDGSFTQNGFKGEYYNTRNLTGELFQAAIEPAIDHAWKYGAPFDGMPVDQ
                     FSARWTGVYKADKDGTVKFQLAGDDGYRLFVNDKLITGDWGNHSFSTRSAFMQVSAGEI
                     YRLRIEYFDNVGEATVSFQAGMMDEERLASSLKHARNVIVCAGFNSSTEGEGFDRPFAL
                     SYGQEYLINKVASLHDNVAVVVNAGGGIDFRNWGQSVQAILMAWYPGQEGGKALAEIIT
                     GKLSPSGKLPVSIEEKWEDNPVYGNYYDNRNVPHKRVQYAEGVFVGYRGYDRNGKQPLY
                     PFGYGLSYSSFEYSNLSVEKTGGSRVTVSFDIKNTGKMDAAEAAQVYVRDVECSVPRPL
                     KELKGYDKVYLKKGETKRVRILLDEEAFAYYDVESHRFVVEKGTFEILAGPSSADLPLK
                     ATVVL"
     CDS             7749..9932
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 84.6; E-value: 1.3e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg25_38"
                     /sec_met_domain="Fn3-like (E-value: 8.7e-27, bitscore:
                     84.6, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 1.5e-74, bitscore:
                     242.6, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 3.1e-52,
                     bitscore: 168.9, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVCLWGLGNTFTSAQTTEKEKFISSLMKQMTLDEKIGQLAQCTYR
                     GNFTGPDGGNIPKEEYVRQGRIGSMLNVIGVKDIRRYQELALQSRLRIPLIFGLDVIHG
                     YRTGFPLPLAEAASFDLAMIEEAARYNALESAADGLNWVFAPMVDISWDARWGRVMEGA
                     GEDPYYGSRVAEARVRGLQGDDLADTTTVMACMKHFAGYGAPIAGKEYNSVDMSMGHFA
                     NFYMPPYKAAIKVGAATVMSAFNDFNNIPCTANDFLLNRLLREQWGFKGFVVSDYNSVE
                     ELVNHRYAVDKKDAAAKALNAGLDMEMVSTCYLTYLKELVQEGKVKESVLDDAVRRILE
                     KKYELGLFEDPFRYCNPERAARILNAPEVRNASLRMAERSVVLLENRESVLPLTAQTRK
                     IALIGGLSKSQYDMAGAWAATTDRNKVVTLYDALVRKGLEVSYAEGYDMKSNQLTGLQE
                     ALQAAEASDVIVVAVGERFGQSGEKASKVNIAIPEGQQKLVSELAKTGKPVIALVMCGR
                     PVIFNEIREHADAVLCTWWLGSEAGNAICNVLWGEYNPSAKLPMTFPAHVGQIPIYYQN
                     KSTGRPTALKQTYKASYIDASTEPAYPFGYGLSYTDFGYSDLKLLPGKAAGVHTEVSVK
                     VTNTGKCAGEEVVQLYVQDKVASVTRPIKELKGFRKIHLNVGESKTVAFQITDDALGFY
                     DNEMNYMVEPGDFVFMVGGSSDDVQQITYNLKE"
     CDS             complement(10001..10726)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 75.5;
                     E-value: 1.7e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_39"
                     /sec_met_domain="Radical_SAM (E-value: 6.4e-31, bitscore:
                     99.5, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCPFRCLYCANPDTIDVKGG
                     TPTTPEEILQMAISQKAFFGKKGGITFSGGEPTLQAEALIPLFKELKANGIHICLDSNG
                     GIWNEKVEELFSLTDLVLLDIKQFNPERHRTLTGRSNEQTLRTAAWLEEHEHPFWLRYV
                     LVPGYSDSEEDTRLLGESLGKYQQIQRVEILPYHRLGVHKYEAMGWDYKLKEVKENTPE
                     QLERAEKLFKEYFTNVITN"
     CDS             complement(10728..12956)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_40"
                     /sec_met_domain="Gly_radical (E-value: 2.4e-46, bitscore:
                     148.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1169.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFTNGLWNKEINVSDFVSKNIAPYTGDASFLQGPTERTKR
                     IWDICLKALEEERNNNGVRSLDNTTVSTITSHKAGYIDKDNELIVGLQTDELLKRSIKP
                     FGGINVVAKACRENGVEVDDKVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGIDRLIEAKQEDLRNLTGPMTEARIRLREEVAEQIKALKDIK
                     VMGEYYGLDLSHPATSAQEAVQWVYMAYLAAIKEQDGAAMSLGNVSSFLDIFIEYDLAH
                     GKINETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTEAIGGRFNDGRVKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKDFCAKVSVDTSSIQYENDNLMREVRNC
                     DDYGIACCVSYQAIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKGIPVLTGETL
                     KFEEVMANYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMAFIDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAKVTARRNEIGLTEGFDTEGSFPCFGNNDDRVDHLGVDLVYYFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGPTPEERVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLEDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             complement(13675..14334)
                     /locus_tag="ctg25_41"
                     /transl_table=11
                     /translation="MEKISFMRRLSSSLIDKVLILVLFIISALCISPYGMASHLGSYYA
                     LLDAVPSSYPAQDTYKAMHSVYDNTIYESTEKWVQCYKEISQKPELIAPHKGETLSWDL
                     QITGLFIIVNFIYYLLWEWIFRASLGKFLCGLTVASDNNQPTTEKEIIKRCFLLLLLMI
                     AAVGLRFTFDINYYMTILLFFLIVDTSVIIKGKSLIDIMTNTYITKRKIYKNENLK"
     CDS             complement(14338..15096)
                     /locus_tag="ctg25_42"
                     /transl_table=11
                     /translation="MKRHNYNIAIAITISCILFFINGYHNYIKDKRKDNLEKYKAGYYD
                     NVTVKNKNIEPSTTKNYVPPKNWTKYIIANAFSISVPPTVELRKSNDSYTKDIKNLNWH
                     GHKINSNNVVFQQKGLSVNTPEAHQTYCRIIIDIQKGSLGEYPKFSDYEDLTIEDIHTF
                     QELAKQNSYEYKILGQPEVRWIKIEDTYGIEVEYVRNGANNSRTHVCNYYFFNDNLFAT
                     IILSYRQDDIRKWETDFSNIIKTFKWNNKK"
     CDS             complement(15168..15356)
                     /locus_tag="ctg25_43"
                     /transl_table=11
                     /translation="FKGALLNVLRGQNRLVLGGSLHWIFHHYPKVIIDFSLFLLVLLLF
                     IPYMNILKRLTLFSSRC"
ORIGIN
        1 caatatgttt cgccgctggt ctatccccgt taggcagtac atcagggagg agaataatat
       61 attgaaggtg tacttccatt cgccggtaaa gatagacgtc cccaaatggg atgcacttcc
      121 ttaccagtat ccggcatcca atgaccagtc tgaaaacgga ggcttgttca acaagaagat
      181 aagcattttt gcccgtaagg cgggttatca ttatggctgg gactggggcc cacgtctggt
      241 tacctccggc atctggcgtc cggtgtatat cagggcttgg agcgatttga gaatcaacga
      301 tgtgtttatc gagcagaagg aagtcggtgc aggcagggcc gtgattgccg gacatgtgga
      361 gctggatgcc gataaggata tggacggagt gctggtcacg ataacagacg aggctaccgg
      421 aagagtgctt ggcgagtggc aagcggattt gaagcgaggc accaatcggg tgaccgttga
      481 tttcgtcctt cacaagccga agctgtggtg gagtaatgga ctgggggagc ctttccttta
      541 ccgtttccgt acggatatca ttgcaggcgg ggaattgttg gactctaaaa ccgaaagggt
      601 gggcatacgc tctttgaagg tggtgcatca gccggataag gacgggcata ctttctatat
      661 agagctgaac gggcgtccgg tttttgccaa aggagccaat tacatccctt cggataactt
      721 cctgccgcgc gtcactcccg agaattataa aaggacgatt ctcgatgccg ccggtgtaaa
      781 catgaatatg ttgcgtgtct ggggcggagg tatctatgag aacgatgtct tctatgattt
      841 gtgtgatgag catggaatta tgatttggca ggactttatg tttgcctgca gcatgtatcc
      901 ggcagaaggc gccctgctcg ataatatcca tcaggaggcg gtggacaatg tgaaacgttt
      961 gcgcaatcat gcctgcattg ctttgtggtg tggaaacaat gaatgccagg atgcctggct
     1021 gggctggggc tggaagtgcg agatagaacg gcagaacaag gaatatgccg acaagatttg
     1081 ggcacagtac cggcagcagt atcatgtcac cttacccggg gtggtcaggg agtatgcacc
     1141 cggaaccttc tattggcctt cttctccgtt cgcattcgag ggagagatgt ccggtactac
     1201 tgacggggac cgtcactatt ggagtgtctg gcatggtaaa gcacccattt ccgattatga
     1261 cagcgagaaa tcccgctttt tcagcgagta cggctttcag tcttttccag agttcgactc
     1321 cgtcaagcgc tatgctcctt accccgaaga ctgggatata cgttccgagg tgatgatgtc
     1381 ccatcagcgt ggtggcgacc atgccaacgg gctgattgag acttacctat tgaatgaata
     1441 taaaaagccg cgtgatttcc gggcattcct ttatatgaac catgtgctgc agggagatgc
     1501 catcaagacg gccatcgagt cgcaccgccg ccagatgccg tataatatgg ggacgctttt
     1561 ctggcagcac aacgactgtt ggcccgtagc ttcctgggcg agccgtgact attacggacg
     1621 ctggaaggcg cagcactatt atactcgcaa ggtctatgat gacatcctga tttctccggt
     1681 agtggagggg gatgatttga aagtatatgc agtgtccgac cgcttggaga atacttccgg
     1741 ccggctgcag ctccaggtct gccggttcga cggcactgtg gtttatcact gggacaaatc
     1801 tgtcggcatt tccggtaatg acagccgtgt ctgtttttcc gcaccgcttg ccaagctgct
     1861 ggagggggca gatagaggaa cggtatatgt ccgcgtagac tatacggaca aatcgggcag
     1921 ggtgtaccat aacaactact gtctggacaa gcagaagaat atgaattatc cgaaagtgga
     1981 tttgcagacc gaagtccgtt ccattgaagg cggatatgaa gtgacggtat caacagacaa
     2041 gtttgcccgt gccgtatgct tgtccgttgc tgacaatgaa agtgtatata gcgacaatta
     2101 ttttgatgtc cagccgaaga gcagcgtgca ggtacaggtc aggacgcgat tgtctgccga
     2161 agcgttcaac gcttcgttga ggctgacttg cttgaacaat gaattctgat aagttatgga
     2221 aaaacaaagc ggagcaacat attgaaatgt tactccgctt ctcattgaga tgttgaaaaa
     2281 tgtgttttca ggagatttag ttgttttctt ttttaatgtc tatggtcatg aaccgttcac
     2341 cgtcatatag acttttgacg cggatgttca gtcctttttt ctctttcagc tgttccgcta
     2401 tattgtccag cttgaaggag gccagtccgg tgctcagtgt gagctggctg tcattgtagg
     2461 cattgtggcg gaattcgaga ttgacgtaat ccggtttgtc gttctcgccg gtggatgctt
     2521 cgttgatgac caggttcagc atgtgcttct tatcttcgtt gttactgtgg tagaattgat
     2581 acttgatgtt cagatactca cccgtaatcc ataaatccgt ggcgttgatg ttgtcgtctc
     2641 cgatactgtc cgccttttcg gcaggcatgg agtagatgtc tttggtcaga atattttcga
     2701 tgtgctttat ttgggcattg tattcgtagc ctggaagttt ctcttccagt tcgcggaagt
     2761 agatgaaagc cctctggccg tctgttacgg catagtcgtg aacataggtt gtgtcactgg
     2821 gatatagttt actgccttcg tccagtgaga aatagtagtc ttttccttcg atgaccttta
     2881 ccgtacctac ggcgaacaaa gtgtcatatt tgtcatccca atcgtccagg catgattgca
     2941 atacaatggc agtcaggaat aaaagcatgg atgttgccaa tgtcattctc agtttcttca
     3001 taagtggtag gttttagctc ttttctgttt aaaacttatt tttgtattca gaaaatgcgg
     3061 tgaaaagcta aatactgcgt agtatatact gttaaagaaa tgaaagtatg attttcttct
     3121 ctgcctgatg cagtattttt gcgccgattg catttatagg gtaaacacgt gttaaaagag
     3181 agaatggaag aacaggaatt ggcagaacgc tgtaggcaag gagacaatct tgcccgcaaa
     3241 gaactgtatg agcgctatgc gggacgcatg ctcagcgtat gccttcgtta tgcaggtgac
     3301 cgggagactg cccaagacct gatgcatgac ggttttctga aactttttga ttctttcgat
     3361 aagttcactt ggcggggaga gggttctctg cgggcatgga tggaacgcgt aatggtgaat
     3421 acggtgttgc agtatttgcg gaaaaatgat gtgatgaatc agtcatcggc cttggagaat
     3481 gcacctgaag cttatgagga accggaaggt tcgtcaatag atgtcattcc tcaaaaggta
     3541 ctaatgcagt ttatcagtga attgcctgcc ggctatcgta ccgtattcaa cttatatatt
     3601 tttgaagaga aatcccataa ggagattgct cgactattgg gaattaatga aaaatcctct
     3661 gcctcgcagt tgacgcgtgc taaagcgact ttagcggcaa aagtacgtga gtggatgaaa
     3721 agaaatgatt aaatgaagga acgtatggaa gatgaattgt ggttgaaaaa gataaaggac
     3781 aagctggaag actattccga accgctgccg gttgccggat gggagcggtt ggagaaggaa
     3841 ttgtccgttt ccggagctcc gataaccgga ccgcatagga tgataccttt ccgtcgctgg
     3901 gcggtggccg cggcagctgt gttgctggtg gcggtttcgt ccgtcagtct gtggctgttg
     3961 cagagtccgg tagggaatga aatgcggcat acgtcagtgc ccgctttggc tgtggctccg
     4021 gacgtcttgc cggaacagac agtacctgcc atacggacta attccataga gcctgcttat
     4081 cgggcacatg gaaatgcatc ggcgcccaat aaggaggcaa gtcacccttt ggttgcacaa
     4141 catatcagaa tatcggttgg cgaagaacag caggaggaaa tgctgccggt tgaaactgca
     4201 gatgaggttg tcggtattgg acagcaggcg gaagaaccgg tagtggaaga tacggaccat
     4261 gaaactacaa tgcagaccga ggaaccggag acaagggaag accgctatcg tccgtcaggc
     4321 cgggacaaac tgcatcttcc ggaaaaaaac agttctggta gggatgctaa aggatgggcg
     4381 gttggcttgt ccgtaggaaa tacgggaggt ttttcattgg cgaatgaagg ggaagcgaat
     4441 gtgatgtcgg actacatgcc tggaagtcct atttatggcg gtaacgtaga tttatcctct
     4501 acggccaatg gcattgttac tattcccgac gggcaggaac tggtttttaa ggatggtatg
     4561 ccctatctgc aaagacgcga aaagaaaatt gcggatatag accataaaca accgctcagt
     4621 ttcggtgttt cggtgcggaa aaacttggcg aagggtttct ctgtggaaag cgggctgacg
     4681 tatacctatc ttgcttctga cgtaaggtat gagggcagct cggaaaagat aagccagaag
     4741 ctgcattata ttggcattcc ggtacgggcc aactggaact ttgtggatgc aaagaacttt
     4801 acgatgtacg tttcggcggg gggtgccatt gaaaaatgtg tgtatggcaa gattggtact
     4861 gagagtgaga ctgtgaaacc ggtacagctt tctgtcatgg gtgctgtcgg tgcccagtat
     4921 aacataagca atagggtggg cctgtatgtg gaaccgggag tatcttattt ctttgatgac
     4981 ggttcgtcga tacagactat acgcaaggag aacccgtgta actttacgtt gcaggccggt
     5041 atacgtctta cttattgata gcaggacaga catgtttttg tccactttct tgtagattca
     5101 gaattttctt aataactttc ggccgtgttt cttcgttggt ggatgaaggg acacggtttt
     5161 ttattgattg agaagaaaga aagtaggtcg ggacatgccc ggcaatataa caaacacgta
     5221 gtaaaataga caaaatgaag attaaaaaga aagtagcctt aagcgggcta ttgctttgtt
     5281 gtgcaatcac ggcaaaagca caagtgtgta ttactcccca ggtggagcag cgtgccaggg
     5341 agttggtttc tcaaatgacg ctggaagaaa aaatcgatta catttccggt cccaaatctt
     5401 tttatatccg ggctgtaccc cggcttggca tacccgaaat caggatggcc gatggtccgc
     5461 aaggcatacg taacaatact caaagtacct tgtatccttg tggcatcttg tcggcttcga
     5521 catggaaccg taagttggct agagagctgg gacatggttt ggcccgggat gcaaaggccc
     5581 gtggggtaag tattctgttg gggcctggag tcaatatcta ccgctctcct ctatgcgggc
     5641 gaaactatga gtattttggt gaagaccctt atttgacggg cgaaactgct aaagaatata
     5701 tcttgggagt gcaggaagag ggagttatgg ctacggtgaa gcattttgcg gccaataacc
     5761 aggagtggag cagacatcat gccagctcag atgtggatga acgcacgctg caggaaattt
     5821 attttcccgc gttccgaaaa gctgtgcagg aagcaggagt aggggcggtt atggatagct
     5881 ataatccgct gaacggggta catgccaccg aaaacagctg gctgaacatt gatgtattac
     5941 gcaagcagtg gggatttaaa ggtatcctga tgtctgactg gacatctgta tattctggtg
     6001 tgggagccgc taatggaggg ttggatttgg aaatgcccgt cggtaaattc atgaccaggg
     6061 aaattcttat tccggcaata gagaatggta tcgtgaagga agagaccatt gacgccaaag
     6121 tccggcatat actccagaca ttgattgctt ttggagcact tgatactccg agagaagata
     6181 aatctatcga taaagacaat gcacagtcta aggaaattgc acttgacttg gcgagagaag
     6241 gagtagtctt attgaaaaat gataacggta cgttgcctta ccggaacggt agaacattgg
     6301 taatcgggcc taatgccgat attattccca caggaggagg aagcggattt gtcacccctt
     6361 attcggtagt gtcactctat gacggtatgg ttcagttgaa gggcggcaga cagatagagc
     6421 tgctgtctga cagcattctt tataaggata tgtcccaaca gatttatacg gatggcagtt
     6481 ttacgcaaaa cggttttaag ggcgaatatt ataatactcg taatcttacc ggagaactct
     6541 ttcaagctgc catagagcct gccatagacc atgcctggaa atacggtgca ccgttcgacg
     6601 gcatgccggt agatcagttt tctgcccgtt ggacgggagt ttacaaggct gacaaggatg
     6661 gaactgtcaa gttccagctg gctggcgatg acggataccg tctgtttgta aacgataagc
     6721 tgattaccgg agattggggg aaccattcat tcagtacccg cagtgcattt atgcaggtca
     6781 gtgcagggga gatataccgg ttgcgtattg aatattttga taatgtgggt gaggcgactg
     6841 tcagtttcca ggcaggaatg atggatgagg agcgtttggc ctcttcactg aagcatgcca
     6901 ggaatgttat tgtatgtgcc gggttcaaca gcagtacaga aggtgaaggg ttcgaccgtc
     6961 cgtttgcatt gtcatacggg caggaatatc tcattaataa agtggcttca cttcatgata
     7021 atgtggctgt ggtggtgaat gccggaggtg gaatagattt ccgcaattgg gggcagagtg
     7081 tacaagctat tttgatggca tggtatccgg ggcaggaggg tggaaaggcc cttgccgaaa
     7141 tcattacggg caagctttcg ccaagtggca aactaccagt cagcatcgag gaaaaatggg
     7201 aagataatcc ggtatatggt aattattatg acaatcgcaa tgtacctcat aaacgggtgc
     7261 agtatgccga aggtgttttc gtaggttata ggggatatga ccggaacgga aagcagccgc
     7321 tctatccttt cgggtatgga ctgtcataca gtagttttga atatagtaat ctgagtgttg
     7381 agaagacggg gggaagccgg gttacggtaa gctttgacat caagaatacc ggaaagatgg
     7441 atgctgcgga agcggctcag gtatatgtgc gggatgtgga atgttctgtt ccgcgtccat
     7501 tgaaggagtt gaaaggctac gataaggttt acttgaagaa gggtgaaacc aagcgcgttc
     7561 ggatattgct ggatgaggaa gcctttgcct actatgatgt ggaatcacat cggtttgtag
     7621 tggaaaaggg gacttttgag attctggcag gtccttcttc agctgattta ccattgaagg
     7681 caactgttgt tttatgataa aataaatatc aaaacaagaa tggcagtatg aaaaagataa
     7741 taatactgat ggtttgtctg tggggacttg gtaacacctt tacctcggca caaactacgg
     7801 agaaggagaa attcatctca agcttgatga agcagatgac gctggatgaa aagataggcc
     7861 agcttgcaca atgcacctac cgagggaatt ttaccggacc cgacggtgga aatattccta
     7921 aagaagagta tgtccggcaa ggcagaatag gctctatgct gaatgtgata ggagtaaagg
     7981 atatacgccg ttatcaagag cttgctttgc aatcgcgttt gcgcattcct ttaattttcg
     8041 gactggatgt tatccacggc tatcgtaccg gatttccgct tccgcttgcc gaggctgcaa
     8101 gtttcgattt ggccatgatt gaggaagctg cacgctacaa tgctttggaa agtgccgctg
     8161 atggtttgaa ctgggttttt gccccgatgg tggatatttc gtgggacgca cgttggggac
     8221 gcgtcatgga aggggccggt gaggaccctt attatggttc tcgggtagcg gaggcgcgtg
     8281 tcagaggctt gcaaggagac gatttggcag acacgacgac tgtcatggca tgtatgaaac
     8341 attttgccgg atatggtgca ccgatagcag gaaaggagta taatagtgtg gatatgtcaa
     8401 tgggccactt tgccaatttt tatatgcctc cctataaggc ggccataaag gtaggagcag
     8461 ctaccgtgat gagtgctttc aatgatttta ataatattcc ttgtactgcc aatgatttct
     8521 tgctcaaccg gctattgaga gagcagtggg gatttaaggg atttgttgtg tccgattata
     8581 attcggtaga ggaattggtg aaccaccgtt atgctgttga caagaaagat gccgcagcca
     8641 aagcgctgaa tgctggtctg gacatggaga tggtaagtac ctgctacttg acttatctga
     8701 aggagcttgt tcaagaaggg aaagtaaagg agagtgtgct tgatgatgca gtacggcgta
     8761 tattggagaa gaaatatgag ttgggattgt ttgaggaccc ttttcgctac tgtaatccgg
     8821 aaagagcggc cagaatactc aatgcgcccg aagtccgtaa tgcttcgctc cgtatggccg
     8881 agcgttccgt tgtattgctg gagaataggg aatctgtgct tccgttgacg gcacagacga
     8941 ggaagatagc cttgatagga ggactctcaa aatcccagta cgatatggca ggtgcttggg
     9001 ctgccactac ggaccggaac aaagtggtga ccttatatga tgcattggtc cggaaaggac
     9061 tggaggtgag ctatgctgaa ggctatgata tgaagagcaa tcagttgacc ggattgcagg
     9121 aagcattaca ggctgctgag gcttcggatg tcattgttgt ggcggtaggc gagagattcg
     9181 gtcagagtgg cgagaaggct tccaaagtga atatagccat acccgagggg cagcagaagc
     9241 tggtgtcgga actggcaaag actggaaaac ctgtcattgc tcttgtcatg tgtgggcgtc
     9301 cggtaatctt caatgagata agggaacatg ctgatgcggt actgtgtact tggtggctgg
     9361 gaagtgaggc cggcaatgcc atatgcaatg tgttgtgggg agagtataat ccttcggcta
     9421 aattgcccat gacatttcct gcacacgtag gacagattcc catttattat cagaataaga
     9481 gcaccggccg ccctaccgca ttgaaacaga cctataaggc atcttatatc gatgcttcca
     9541 ctgagcctgc ctatcctttc ggatatgggc tttcgtacac ggattttgga tattctgatt
     9601 tgaaactgct gccgggcaag gctgcaggcg tccatacgga ggtgtcggta aaagtgacta
     9661 ataccggtaa gtgtgcagga gaggaagtag ttcaattgta tgtgcaggat aaggtagcct
     9721 ctgttacgcg tccgataaag gaattgaagg gcttcaggaa aattcatctg aatgtgggtg
     9781 aaagcaaaac tgtagctttt cagataactg acgatgcact gggattctat gacaatgaga
     9841 tgaattatat ggtagaacct ggtgatttcg tctttatggt gggtggcagt agtgatgatg
     9901 tacagcagat tacctataac ttgaaagaat aggattctta ccctataaat gaaaagcaag
     9961 gctgtctgga atcatatccg gacagccttg cttttctgtt ttagttggtt atcacattcg
    10021 tgaaatactc tttgaacagt ttttctgccc gttccagttg ttccggagta ttttccttca
    10081 cttctttcaa tttgtaatcc catcccatgg cttcgtattt gtgaacaccc agacggtgat
    10141 aaggaagtat ttccacccgt tgtatctgct ggtatttgcc aagactttca cccagcaggc
    10201 gggtgtcttc ttccgaatcg ctgtaaccgg ggaccagtac atagcgcagc cagaaggggt
    10261 gttcatgttc ttcgagccag gcagcggtgc ggagtgtctg ttcgttgctt cgtcccgtca
    10321 gcgtacggtg gcgttcggga ttgaattgct tgatgtccag cagcacgagg tcagtcaggc
    10381 taaagagctc ttccaccttt tcattccaga tgcctccgtt actgtccaga cagatatgga
    10441 tgccgttcgc cttcagctcc ttgaaaagag gaatcagcgc ttctgcttgc agggtaggct
    10501 caccgccgga gaaagtaata cctcctttct tcccgaagaa tgccttttgg ctgatagcca
    10561 tttgcagaat ctcttccgga gtggtgggag tgcctccttt tacatcaatc gtatccggat
    10621 tggcacaata cagacaacgg aacggacatc cttgcaggaa aacgacgagc cggagacccg
    10681 gcccgtcgaa tgttcccata ctttcgtagg agtgtacatt tatcatatta cattctttcg
    10741 tggaatgaac ggctgatgac ttccaactga tgctcgcggc tcaacttcac gaagttcacg
    10801 gcatagccgg aaacgcggat ggtgagttgc ggatactttt caggatgttc catggcatct
    10861 tccagcattt cgcggttcag tacgtttacg ttcaaatggt gggcaccttt ggtgaagtag
    10921 ccgtccatca tggttaccag gttctctaca cgttcttccg gtgtcgggcc cagtgatttg
    10981 ggaacaatgg agaacgtatt gctgatgccg tcctgcgagt cgcggtagcg caatttggct
    11041 acggagctca aggaagcgat ggcaccgttc ttgtcacgtc cgtgcattgg gttggcaccc
    11101 ggagcaaagg caacaccttt ggcgcgtccg tccggagtgg caccggtctt cttgccgtac
    11161 atcacgttgg aggtgatagt cagcaaggaa agggtgggac gggcattctt gtagacaggc
    11221 agctttttca gttcttcgct gaaatagtaa acgaggtcta ctcccaggtg gtccacacgg
    11281 tcgtcattat tgccgaagca ggggaatgaa ccttcagtgt cgaaaccttc ggtcaggccg
    11341 atttcgttgc ggcgtgcagt gactttggca tatttgatgg cggacagtga gtctatggcg
    11401 atggaaaggc cggcaacacc gtatgccaga ttgatgcgtg ggtcggtatc gatgaatgcc
    11461 atctgggctt tctcataata atacttatca tgcatgtagt ggatgatatt catggcctcg
    11521 ttgtagacac gggctatttc agtcagtacc ttcttgtagt tggccataac ttcctcaaac
    11581 ttcaatgtct caccggtcaa tacgggaata cctttcacca tgacagttcc ggtattttcg
    11641 caacgtccac cgttgatggc gagcagcagg gccttggcaa ggttggcacg tgcgccgaag
    11701 aactggattt gtttgccgat ggcttggtag gatacacagc aggcgatgcc gtagtcgtcg
    11761 cagttgcgca cttcacgcat caggttgtcg ttttcgtact ggatggagct ggtatctaca
    11821 gaaactttgg cgcagaaatc cttgaagcct tccggcagtt cgggactcca caatacggtc
    11881 aagttcggtt ccggagaagg accgaggttg tatagcgtct gcaaaaagcg gaaagaagtc
    11941 ttggtgacct tcacgcgtcc gtcattgaag cgtcctccga tggcttcggt cacccaagtc
    12001 gggtcaccgg caaagatatc attgtatgat tgcatacgca gatggcgtac catgcgcagc
    12061 ttgatgacga actggtctat cagttcctgt gcaaacgtct cattgatttt tccgtgagcc
    12121 agatcgtatt caatgaatat atcgaggaac gaagatacgt tacccagtga catggctgct
    12181 ccgtcctgct ctttgatggc agcaagatat gccatgtata cccattgcac ggcctcttga
    12241 gctgatgtag ccggatggct gaggtcgagt ccgtaatatt cgcccataac cttgatgtcc
    12301 ttcaaagctt tgatttgttc tgccacttct tcgcgtagac ggatgcgtgc ttcggtcatc
    12361 gggccggtga ggttgcgcaa gtcctcctgc ttggcttcaa tcagacggtc gatgccgtag
    12421 agagccaatc ggcggtagtc gccgatgata cgtccgcggg catagttgtc gggcaatccg
    12481 gtaaggaatc ccagtgagcg gaaggaacgg atttcttcgg tatatacatc gaatacgccg
    12541 tcgttatgtg ttttgcggta atgggtgaag atgtctttta ctttatcgtc cacttccact
    12601 ccgttttcac ggcatgcttt tgctaccacg ttgatgcctc cgaaaggttt gatggatcgt
    12661 ttcaacagtt catcagtctg caaaccgaca ataagttcat tgtccttatc aatatacccg
    12721 gctttatgag aagtgatggt agatacggtg gtattgtcca gtgaacggac gccattgttg
    12781 ttcctttctt cttcgagagc cttcagacag atgtcccaga tacgtttggt acgttcggta
    12841 ggtccctgca agaaagatgc atccccggta tagggtgcga tgtttttact gacgaaatca
    12901 ctgacattga tttctttatt ccaaagccca ttggtaaagg ttttgttcaa ttccataaaa
    12961 tttgtttttg ttagtaggtt agataatgtt atcctttaga gcgcgcaaaa atactgaata
    13021 aattccgtaa ttttataaga gatacttctc tttttatgtt gaacagcata aaataactat
    13081 tattaggtag tgaatgtccg ggggagtaga gatgttaata ctttctttat atgtggttta
    13141 tgaattgaaa caagaaccga ataataatct gcattattta caaatgatgt aggtttaagg
    13201 aacagtcgta ttctgaacct aattcagtcg tatagtgaat gccattcagt cgtatactga
    13261 atagggttca atcgtatact gaatgtggct ctttgtaaat atactgatag ccagtaagtt
    13321 ataaaactct gtcttgccct tgataaattt caacaaatag cctaaatgcc gttatgttcg
    13381 ttccgtagtg ggtataaaca agaattttgg tataattgct ctgtttttgt gcagaaaagt
    13441 ttgtagaata aaaaatgatt tgtatctttg caccgcttta aaagaaaagc acttctgaaa
    13501 aagaagtttt ggagaggtgg cagagtggtc gattgcggcg gtcttgaaaa ccgttgtgct
    13561 gcgaggcacc cggggttcga atccctgtct ctccgcaata aaccttgata attagcggtt
    13621 tataagattt acacccagtt ttacacccta taatgtaaaa ctgggtgttt tgttttattt
    13681 aagattttcg tttttataga tttttctttt tgtgatatat gtgttagtca taatatcaat
    13741 taatgatttc ccttttatga ttacagatgt gtctacaatc aggaaaaaca ataaaatagt
    13801 catgtaataa ttgatgtcga aagtaaatct tagacctact gcggctatca ttaagagtag
    13861 taataagaaa cagcgtttga taatttcttt ttctgttgtt ggttgattat tatcggaagc
    13921 aacagtaagt ccacatagaa atttgcctag tgatgcgcga aatatccatt cccataaaag
    13981 ataatatata aaatttacaa ttataaaaag ccccgttatt tgtaaatccc aagatagggt
    14041 ttcaccctta tgtggagcta ttaattcagg cttctgtgat atttctttat aacattgaac
    14101 ccatttttct gtactttcat aaatagtatt gtcataaaca ctatgcattg ctttatatgt
    14161 atcctgagcg ggataagatg atgggactgc atctaatagg gcgtaataac ttcctaaatg
    14221 agaagccatt ccgtagggag atatacataa agcactaata ataaataata ccaggattaa
    14281 gactttgtct attaaagaac ttgataatct tcgcataaaa ctaatttttt ccataactca
    14341 ttttttatta ttccacttaa atgttttaat tatatttgaa aaatctgttt cccattttct
    14401 tatatcatct tgtctatatg ataatattat tgttgcaaat agattgtcat taaagaaata
    14461 ataattgcag acgtgagtac gggaattgtt tgctccattt cgcacatatt caacttctat
    14521 tccgtaagta tcttcaatct taatccagcg cacttctggt tgacctaaaa ttttatattc
    14581 ataagagttc tgttttgcta gttcttgaaa tgtatggatg tcttctatag tcaaatcttc
    14641 gtaatctgaa aatttagggt attctcctag acttcctttt tggatatcta ttataattcg
    14701 gcaatatgtt tgatgcgctt cgggggtatt aacagataac cctttctgtt gaaaaacaac
    14761 attattgcta tttattttgt gtccatgcca attcagattt ttaatatctt tagtgtatga
    14821 atcattactt tttcttagtt caacagtagg aggtacacta atagaaaaag catttgctat
    14881 tatgtattta gtccaattct tgggaggaac atagtttttt gttgtactag gttctatatt
    14941 tttgtttttg accgttacat tgtcatagta tccggcttta tatttttcta agttatcttt
    15001 tcttttatct tttatatagt tatggtaacc attaataaaa aaaagaatac aactaattgt
    15061 gatagctatt gcaatattat aattatgtct tttcatattt ttattttagg gtaattcttt
    15121 aaatccacga taaatccata tagtagctat ataagtaata atctcaacta gcagcgtgaa
    15181 gaaaaaagtg ttaacctttt caggatattc atgtacggta taaacaataa taagacaagc
    15241 aaaaacaatg agaagtctat tataaccttt gggtaatggt ggaaaatcca gtgtaagctg
    15301 ccccctaaaa ccaagcgatt ctgccccctt aaaacattca acaatgcccc cttaaa
//
