LOCUS       gnlProkkaKFACAOEJ_53   10898 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KFACAOEJ_53.
ACCESSION   gnlProkkaKFACAOEJ_53
VERSION     gnlProkkaKFACAOEJ_53
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 03:41:23
            Original ID  :: gnl|Prokka|KFACAOEJ_53
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10898
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10898
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1584:5898]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1585..5898
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10898
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10898
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..362
                     /locus_tag="ctg21_1"
                     /transl_table=11
                     /translation="MREGDVISIPKNTNTVTINGAVMVPNTVSYMKGKNVDYYLNQAGG
                     CSDNARKSKKFIVYMNGQVTKVKGSGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFS
                     SLGMMIASIANLIKK"
     CDS             373..1521
                     /locus_tag="ctg21_2"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             1585..2304
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 8.7e-16, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             2325..3626
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_4"
                     /sec_met_domain="CTP_transf_like (E-value: 1.1e-12,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.1e-120, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.2e-62, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             3643..4767
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5.8e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             4777..5898
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg21_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_6"
                     /sec_met_domain="Aminotran_5 (E-value: 8.2e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        4867..5874
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg21_6_Aminotran_5.1"
                     /locus_tag="ctg21_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             5895..6038
                     /locus_tag="ctg21_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             6241..7725
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_8"
                     /sec_met_domain="Polysacc_synt (E-value: 7.3e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             7679..8938
                     /locus_tag="ctg21_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             8947..9696
                     /locus_tag="ctg21_10"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             9696..10736
                     /locus_tag="ctg21_11"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 tcttacgtga aggtgatgtg atctccatac ctaagaatac taatactgta actatcaatg
       61 gtgctgtcat ggttccgaat acggtttctt atatgaaggg aaagaatgtg gattattacc
      121 tgaatcaggc cggtggctgt tctgataatg caaggaagag taagaagttc attgtttaca
      181 tgaatggtca ggtgacgaag gttaagggta gtggtaagaa acagattgag ccggggtgtg
      241 agattattgt gcctggtaag gctaagaaga aagggaacat agctaatatt ttaggttatg
      301 ctacttcctt cagttctttg ggaatgatga ttgcttctat tgctaatttg ataaagaaat
      361 aaatgaccta ttatgattga aaagcaatct tatcaagaac cgttttctga agtggataaa
      421 aggaaagatg atgaaatgga aatagacttg atggctattt tttataagat tattactgtt
      481 cgtggagtac tatgcaaagc tgctggagtg ggagtaataa ttgctatagt ggtggcattg
      541 agcattccca agcaatatac agtaaaggtt accctttctc ctgaaatggg taatgcgaag
      601 ggaagtaatg gtttagccgg acttgctgcc tcgtttttgg gagatggggc tctaataggg
      661 gaaagcacag atgccttgaa cgcttctctt tcagcagata ttgtttcttc aactcctttt
      721 ttattggaac ttttagaaat ggaagtctcc gtttctaaaa aggatgataa aatgactttg
      781 gggtcttatc tcgatgaaga gtcatctcct tggtgggatt atcttatagg ttttccgggc
      841 atagtaatag gaggagttaa atcattattc ggagaagata cggttcctgc cagtggaggg
      901 cggcaaggaa ctatcgaatt gacgaaagaa gtaaatgaga agattaattt tcttaaaaag
      961 aagattagtg catccattga taagaaaacc gccataacga gcattacggt caccttacaa
     1021 aatccgcaga tcactgcggt tatagcagat tctgtcgttc ataaattaca ggaatatatt
     1081 attgggtatc gaacttcaaa agtaaaagaa gactgtgcgt atttggaacg gttgtttaaa
     1141 gaacgtcagc aggaatatta tgctgctcaa agaaaatatg cggattatgt agacgcccat
     1201 gataatgtgg ttcttcaaag tgtacgtgct gagcaggagc gtttacagaa cgacatgagt
     1261 ttggcttatc agatatatag tcaggttgct aatcagttgc aggtatccag agccaaagta
     1321 caggaggaaa agccagtctt tgcagtagtt gagcctgccg ttgtaccttt gaaaccttca
     1381 ggtatgggac tcaaaattta tattttatta tttgtgttcc tgtccgtatc tggtactctc
     1441 gtgtgggtgt tttttggcaa aagtctgctg gctagcttga gaaaagaact gaaaaataag
     1501 gagatagaac aggataaatg atgctaaaac gtcgtttaca acattcttac atcaattaaa
     1561 ttcacttact atattattaa acgaatgata cgtacagcta tgataatggc tgcgggcatg
     1621 ggaacccgtt ttggccaata tacagaattg atacctaaag ggttcgtcaa agtgggaggt
     1681 attccaatga tagttcgttc tattgatact ttgttatcat gtgacattga gcgaattgta
     1741 atcggtacag gatataaaca agaagtttat gaagaattga agacagacta tcctatgctt
     1801 gaaacctgtt ttagtcctcg ttatgctgaa acaaatagta tgtatacttt atataatacg
     1861 cgggagattc tgggcaatga tgatttttta ttgttagagt cagatttgat ttttgagaaa
     1921 caagcaataa tgagcttatt ggagtgtcct gcggcagatg caatgctaat aactccagtg
     1981 acaaagtttc aagatcagta ttatgtggaa catgatgata attttcgcct ttcttcatgt
     2041 tctgtcaata agaataaact aaacgctaaa ggcgaattgg tcggcatcca taaactatcc
     2101 ggttcctttt acaaaataat gtgtgctgat tatgcgagta ttgttgatga acaacccaat
     2161 ttgggatatg agtatgaatt actacgaata tcttgttctc aatctcctgt ttatgtgcat
     2221 aaagtagaag ggctgaaatg gtatgaaatc gatgacatat cagatttgga atatgcagag
     2281 aaatatattg ttccgtattg ttaattaaaa taatatatca aattatgagt aagacagttt
     2341 atattgggat gactgcggat attatgcatc caggacttat ccgcattatt aatgaggcta
     2401 ctaaatacgg tgatgttata attggtcttc ttacagataa agctattgcg gagcataaac
     2461 gccttcctta tctgacctat gaacaacgaa aagaggtagt tcagaatatt aaaggcgtat
     2521 gtaaagttgt tcctcaagaa gaatggagct atgttgagaa tctcaaacgc attaaacctg
     2581 actatataat tcatggtgac gactggaaaa ccgggccttt acgtgaagaa cgtgtgcgcg
     2641 tatttgaagt gatgaatgaa cagggaggaa aggttatcga aattccatat actttgggaa
     2701 ttaattcatc ttctttggat aaagatatta aggctatagg tacaacccct gatgtacgtt
     2761 taaaatcact tcgtcgtttg ataaatgcca aacccgtagt tcgtattttg gaagctcatg
     2821 atggactatg tggcttgata attgaaaatc aggaaatatt aaaaggggat aagagggaag
     2881 tatttgacgg aatgtggtct agtagcctta cggattcaac cagtaaaggt aaacctgata
     2941 ttgaggcggt tgatttaact acccgattgc aagatttgaa taatattctg gagtgtacta
     3001 ctaaacctat tatttttgat ggagatacag gtggtaaaat tgaacatttc gtatttacag
     3061 tacgcacttt agaacgtcat ggaatttcag ctataataat tgaagataaa gttggattaa
     3121 aaaagaattc attgtttggt acagatgtta ttcaaactca agatacaatc gaaggtttct
     3181 gtaataagat caaagcagga aaggcatctc agattactga tgattttatg attatcgctc
     3241 gtattgagag ccttatagcg ggaaagccgg taagtgatgc tttagagaga gcttttgcat
     3301 atgtccaagc gggagcggac ggtattatga tacatagcaa aaataagtcg ggtgaagata
     3361 taaaagaatt ttgtttggcg tttcgaaaac agtatgctca tgtacctatc gtggttgtgc
     3421 ctactacata tgatcatatt tatgagtctg aattgtgtga ttggggtgtg aatataatta
     3481 tttatgctaa tcatatgctt cgtgccgctt atcctgctat gatgaatgtc gcaaagataa
     3541 tattagagaa tgaacgtgct ttagaggtgc gcgaactgtg tatgcccata aaagaaatat
     3601 tggaactgat tccaggtact aaataaaaag aggaatatca ttatgttaag cgtagaaaaa
     3661 gtttatgaga cgtttctgag tcatgacgtt gattttttta caggagttcc agactcatta
     3721 ctaaaaaata tttgtgccta tatcacagac catacttcac gtgagaaaca tatcatagct
     3781 gctaatgaag gtgcggctgt aggaattgct tcaggttatt atatggcatc aggtaaggtt
     3841 cctgtggttt atatgcaaaa ttccggcttg ggtaatactg ttaatcctct gctgtctctt
     3901 gcagatgaac aagtatacag ttttccaatg cttttgatga ttggctggcg tggtgaaccg
     3961 ggaacaaaag atgaacctca gcataaaaaa cagggtgagg taactttaga tttgttgaaa
     4021 gcaatgcgga ttccttatat aattcttgat tcaaatgaga atgatgcatt tattcagctc
     4081 catgatatca tacaatcagc aaaaactaag aatattcctc atgcaataat tattcggaaa
     4141 gatgtttttg gcaaatataa acttcaaaaa gagttcggat gtaattatcc tttatctcgt
     4201 gaggatgctt tgcaaatagt tgtggattat ctgcctgaaa attcagtggt cgtttctact
     4261 actggcaagc tttctcgtga gttatttgaa tatcgagaaa tgaaagagca aggtcatgaa
     4321 catgattttc tcacggtagg ctctatggga catagttcat caatctcttt gggtattgct
     4381 atagcaaagc aagatagacc tgtttattgc ttggatggtg atggagcatt tattatgcat
     4441 ttaggggcaa ttagtaacat tggcgattta tctcctaaaa actattatca tattttgttt
     4501 aacaatggtg ctcacgagtc tgtaggagga cagcctactt taggatttag tttagatatt
     4561 ccggctattg tccgggggag cggatataag catacttata ctgtttgtac aaaagttgaa
     4621 attgaagaag caatgaagca gcttccaaag ttatgtggtc ctgttttgtt ggaaataaag
     4681 gttaaaatag attctcggga gaatttggga cgtcccacga ctactcctat agagaataag
     4741 gagcatttta tggatttttt aaaataaata tattcgatga aaatagaaag aaaaatatta
     4801 ttaaatcctg ggcctgccac tactactgac agtgtaaaaa tggcacaagt tgttccggat
     4861 atttgtcctc gcgagaaaga attcgcaggt atgatgaaac aacttcggga cgatttggtc
     4921 agagttgctc atgggaattt ggaaaaacat accgctgtat tattttgtgg ctcaggaacc
     4981 atcaatattg atatatgtct aaattctctt cttcctgaag acaaaagggt gcttatagtg
     5041 aataatgggg catatagtac ccgtgctgta gaagtgtgtc aatattatgg tttgcctcat
     5101 attaatttgg aattttccgt ttacgaacgt cctgatttat cggtggtgga aaatgtgttg
     5161 caagaaaatc ctgatatagc tatggtttat actactcatc acgagacggg tacaggaatt
     5221 ctgaacccta ttcgcgagat gggcgctata gctcataaat atcaggctaa atttgtcgtc
     5281 gatactactt cttctttggg catgattcct tttgatatag agaaagataa tgtggatttt
     5341 tgtatggcat ctgctcaaaa aggacttcaa gcgatgacag gtctttcttt tattataggc
     5401 aatgaggaac agattaagtt ttcaaaaaaa tatcccaagc gttcttacta ttgtaatctt
     5461 tatttgcagt atgagaattt tgagagaaca ggtgaaatgc attttactcc accggtacaa
     5521 actatttacg ccactcgtca ggcattaaat gaatattttg aagtgggtga agaagctaag
     5581 tttgcccgtc acaaaagagt ttttgaggct attcattcag gtataaatga aattggtctt
     5641 aaaagtgtaa taaagcgtga atggcagtca ggactggttg tctcagttca atacccagaa
     5701 gatcccaact gggattttga gaaaatacat gattattgtt atgagcgtgg atttacgatt
     5761 tatccaggta agatatcaac tgaggatact tttagaatct gtgctttagg agagatagaa
     5821 gtagatgata ttgagaactt ctttaaagta ctaaaagctg cattaaatca ttataacgtc
     5881 acattaccga tgtcatgatt gcagaaatat tattgaagat tcgtcatttt tatttttccc
     5941 ttcgtggtat acacttccat ccggaaagtg ttatttctgg agtgcctatt cgtagctttc
     6001 gcttagtagg caaatatggc aatattaatt tgaggtgatg cattaggagt tctttattct
     6061 tataaaaagg catcggtagt tataggagat aatgtttgtg tagggtaatt tgcttttagt
     6121 gggagagacc atattagaat tgcggtaagg ggcgaagaag ataataacca attagtgaga
     6181 atattggaaa aatataattg atatcggtaa atgtagttgt ttttatactg tatttaagta
     6241 atggaaaatc taaagcagaa aactgtatca ggaataatgt ggagcgctat agaacgtttc
     6301 tctttacaag gagtacagtt tataattcaa ataatattag ctcgtttgtt actaccatcg
     6361 gattatggta tgatcgggat gttagctatt tttcttcaag tcgctcaagt atttatagat
     6421 agcggtttta caaatgcttt aatccagaaa aaagatagaa ctgaagagga ttttgccact
     6481 gtcttttatt ttaatattct tgtcgcagta ttattctatg gtatattgtt tttttcggct
     6541 tctttgattg cagactttta taatatgccg actttagttc ttgtaattcg ttttatagca
     6601 ttgtcgttga taataaatgc tttatcggct attcacagaa cgaaattaat tatttctgta
     6661 aactttaaaa ctcaatctaa aatttcatta ggtgcagctt ttatatcagg cgtgattgga
     6721 atatggatgg cttatgtcgg ttgcggggtt tgggctttag tttggcaaac tctcttaaat
     6781 agtataattt tgacaatttt gttttactgt ttagttcatt ggaaaccttt acatactttc
     6841 tccaaaagtt cttttgaaag attattcaat ttcggatcta aattattgat ctcaagtctt
     6901 atcaatacag tatatcgtaa tctgtatacc attgtaatag gaaaaaagtt ttctgttgta
     6961 gagcttggtt actatacaag agcagaacaa tttgctattt ttccttccaa taatttaaat
     7021 gctttagttt ctagagtagc gtatcctatt ttaagttcca ttcaagatga tgataaatgt
     7081 ttaacaaacg catatcgaaa ttatatcaga ttatcctcat atataatttt tcctttaatg
     7141 gtaggtttac ttgttttggc taatcctatt attagtctat tgttaacaga taaatggtct
     7201 ggggttgtta ttcttttaca gatattatgt ttggattgga tgtttgatca tttgagccaa
     7261 attaatttga atttattatg ggttaaagga agatctgatc tgtcgttacg tcttgaaata
     7321 ataaaaaaga cgattgctat attcattctt tttgtgtcaa ttccatttgg gcttgaggtg
     7381 atgtgttggg gtagagttat ttactctctg atagcgacat atttgaatac atattatact
     7441 aattctctta ttgatttgac cttaaagttg caagttaaag atgtatttcc aagtttaata
     7501 ctctctttca taatgggggg gatcgttttt atatgtattt ctttctttga aactgatata
     7561 gtaaaaattg tgattggatg tattactggg atgtccttct atattttact ttcttttctt
     7621 tttaagctag attctttttt ttgtatttta acattgatca ttaaaactaa aaacatagat
     7681 gaaaatatta aaaaagattt ttcaagtaat agtaaagata attaaccatt gtgtgccagt
     7741 tgatagtaga tcattgtatt ttattcctca tcctaattgt agaacagata aatatgatat
     7801 tataaattat tcgtcagata atgttctcgt tctgttaaat tatttgctaa aaaaagatag
     7861 tgctgaatat tataaaatat atgttgaaat ttatgattct tctcgtattt cagaatatca
     7921 agaatatatt tatggcataa atcctaatat taggtgtact tttttatgtg catgtgttgg
     7981 acgttttttc tttaataaag tatcttttaa ggatatgttg tatgcctttt tttgtttttg
     8041 tagagcaagt aaatgtttta cagctacttt ttattatgat ttttcattta aaaaacgctc
     8101 tcaacagatt atttgtttgg ggtattatac tccattcaaa gatgattatc atatgggaga
     8161 tcattcttat gataaatttc gtaatacaac atgtaactca tttgattact ctattgctac
     8221 ttcttgttta agtgctagaa taatttcaat agattgtgga atctcatatg ataaattcaa
     8281 agtcttagga tttcccagaa atgatttgtt gatatcgaaa aataattgca atgttattaa
     8341 aagagaaatt tcgaaatttg cgggatatga tgtaactaaa tatatagttt atactccaac
     8401 ttttcgtgat tatgagactg ttactgaagg taatttgcgt tcaatactcg gatatgttga
     8461 ttgtgatttg ttgaagttat cgaaaatact attgaagttt aatgcggctt taattcttaa
     8521 attacatcct ttgcagaata aaacagtctt aaaaaaagat ttacccaaag gtatacttgt
     8581 ttttgaacaa acatataaat atggattgta tgatcttttg tcattttcag atggaatgat
     8641 tactgattat acttctacct attttgattt tttattggta aataagccag tcatatttaa
     8701 tttctacgat attgaagaat atcgtagagt aagaggtttc tcatttgagc caatagaatt
     8761 tttttgtgca ggtgatattg tttacaatta taatgaattg atagatgctg tgatgggact
     8821 tctggctggg aaagatattc atgctgaaca tcgacgtcat atttctttat tgatgaatca
     8881 atttcaagat gataattcaa caaagagaat atgtgacata tttttaaatg aaatataata
     8941 aataaaatga attatgcatt tgtggtgcag gcacgtttag gttctacacg tttgcctgga
     9001 aaaatattga aacctttcta tggtaatcaa tcgattcttg acttaatggt tcataagctt
     9061 tctgctatat cgaatattcc agtaattatt gctacaacaa attctgttat caatgaacct
     9121 attgaaaaga aggcacttgc attaggggta aagtgcttca gaggtgagga gaatgatgtt
     9181 ttaaaacgat tcattgatgt tgctgaatat tttgatatac agggtatatt ccgaatatgt
     9241 tctgataatc catttttaga tgtacatgcg gcaaggcaat tggtcgaaat agcaatgaaa
     9301 tcttgtaacg attatataag ttttgatatt gatggtactc catcaattaa aactcatttc
     9361 ggtttttggg gagaatttgt aacgcttgat gcgctgaagc gagttatagg atttactgat
     9421 gatttattgt atcgtgaaca tgttactaat tatatatata gtcatcctga actttttaat
     9481 attcaatgga tttcaggatc tccagtcgtg tcaaaacatc ataatattcg actcacgatt
     9541 gatacgttag aagatttttc tgtagcacag agaatatata gggatttaca agaaaaaaga
     9601 gtggaaatat cgatagaagt gattgtagac tatgttcgaa gacatgcaga atacattcaa
     9661 ctgatgaaac aacaaataaa aaaaaattct aaataatgaa gaatacttat attattggtg
     9721 aaatagggca gaatcataat ggttctgttg acttggctaa gttgattatt gaattaatct
     9781 cacgacctgt acatgaggat gtttttggta tggatttcat gccaatgaat gctgttaaaa
     9841 tgactaaaag agatttatca gaagaattgg ctgtttctca aatgaatcaa atatatgaca
     9901 atcctaattc ttttgggcgt acttatggtg aacatcgtgc ttttcttgag cttgatgatc
     9961 aagcgcattt tgagatttat aaatatgcta agtcattagg attagatttt atcgagacgt
    10021 tatgtgccaa aggatgtctg tctttgctta aactgttcac accggatagg ctaaaagttg
    10081 ctagtcgtga tttgactaac ttaccattgc ttgaagcatt agcagaaact catattccta
    10141 ttatattatc gacaggaatg gctggtcaaa gagaacttga caatgcatta gatgtgataa
    10201 cgagatatca tagtaatata gctattctac attgtgtatc tcagtatcca actcatccaa
    10261 ataatttgaa tctacgtaca ataacatatt tgaagaagca ttacaataag tttgagatag
    10321 gtttttctga tcatacaata ggtatttctg ctgctacagc tgctgtagcg atgggagcgg
    10381 aaattataga aaagcatgta acaattgatc ggcatatgaa aggaacagac cagcttggct
    10441 ctttaggtcc agatggggtt aatcgtatga ttcgagatat tcgcatagca gagtgttggc
    10501 ttggtactga agatctttat atagaaaaag gggtggagaa gtctaagata aaacttgaac
    10561 gttctattgc cactcgaaaa tatattccag caggtagtat tattcaagag tcggacattc
    10621 atttactgag tcctggtgat ggttataaat ggatagataa aaaaaatgta attggtcatt
    10681 ttgctaaaca agatatatca gcgaatgaaa taatatatcc tgattttatt gaatagatat
    10741 attcctactg caacttgtat tacggtatag agtactgcct gctataagct aagtagtgat
    10801 taataaataa gggtaaaata ctaaaaaaat gaaagagata aagcttatac ttacagatat
    10861 tgatggcgtt tggactgatg gcggaatgtt ttatgatc
//
