LOCUS       c00003_gnlPro..        17000 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LFEPMIAA_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 23:08:12
            Original ID  :: gnl|Prokka|LFEPMIAA_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 5905
            Orig. end    :: 22905
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17000
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[15905:18878]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12973
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17000
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17000
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(1546..2106)
                     /locus_tag="ctg3_6"
                     /transl_table=11
                     /translation="MMVYVMRNGRRVIAALSFLLLCCGVHVHAQRVAVKTNALGWLTAS
                     PNVEAEFVLGSHVSLNMGIAANPISTDNFKTTFTHFQPEVRYWLNRPMVSHFLGITAFV
                     NNFDMMVKDVHHKGDAYAAGLTYGYAWVLGDHWNIEATAGVGVLRYRQFKYDKGTPKPG
                     AVNDSKTTIAPVKLGVSFVYIIR"
     CDS             complement(2333..4831)
                     /locus_tag="ctg3_7"
                     /transl_table=11
                     /translation="MYWKSHATEVYVKGETFDHAGGEKAPYPTVRYTGTRGTAATHGRP
                     KLADVVPYDDEDGNVTFCNNALPDRPMESVHPSKTGRNIESLNCEILGIARDAAFLYWM
                     TDEEKFAKLAAGVFDTYMTGIYYRNVPIDLNHGHQQTLVGLTSFEVIHEDALHIAVPLY
                     DFLYNYLKANYPDKMEIYAGAFKKWADNIIANGVPHNNWNLLQARFIMNVGLVLEDNKE
                     YADGKGREYYIDYVMNRSSIRQWSLTQLADYGFDINTGIWAECPGYSSVVINDYANFVN
                     QFDTNLQYDLVKAMPVLSKAVATTPQYLFPNRMICGFGDTHPGYLSTNFFIRMIQNAQA
                     NGKKEQENYFTALLKCLNPDLGNDKTEKKNVRVSVNSFFEDKPLALNPKVQPGKIEDYV
                     SPLFYAPNVSWLVQRNGMHPRNSLMISLNGSEGNHMHANGISMELYGKGYVLGPDAGIG
                     LFLYSGLDYAEYYSQFPSHNTVCVDGISSYPVMKSNHSFDLLSCFPASAEPGKAFTSVT
                     YSNLYFREPESRADQTRMMSIVTTGAETGYYVDVFRSRKEKGGDKMHDYFYHNLGQTLT
                     LTAADGSDLNLQSTEELAFAGAHLYAYSYLYDKKVAATNKDVKATFTIDMKDKDGDDIY
                     MNLWMKGEPDREVFTALAPMTEGLSRTPNMPYNIKEQPTLTFVARQHGEAWNRPFVSIY
                     EPSTKKEPSAIQSVSYFDAEGAGLEDFAGICVKSKNGRIDHIFSLSDAAQTAIYQGMKV
                     KADYAVISNEYAGNRTLFLGNGTQLVAPGVMIQTDNAANVLLEKKEGKWYIISSAPCTV
                     VIGDKKIKSDASSEPMLLRI"
     CDS             complement(5284..5418)
                     /locus_tag="ctg3_8"
                     /transl_table=11
                     /translation="MPYSLYHRRSESEDVAHRMPVRNTFQSPFHYFLRAMKDCALLSS"
     CDS             complement(5448..5687)
                     /locus_tag="ctg3_9"
                     /transl_table=11
                     /translation="VLGVADGMFRFGIYIQQPFDSSSSDDMLVDDFFRIFGSDLGVKGI
                     IGDNFHDRTFFTEAETAYGDDFYFIGDFVLFDGF"
     CDS             5688..7157
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH_4Fe-4S"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_10"
                     /sec_met_domain="Fer4_7 (E-value: 2.1e-10, bitscore: 31.7,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 5.2e-11, bitscore: 32.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.2e-50, bitscore:
                     161.9, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0004, bitscore: 11.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="NADH_4Fe-4S (E-value: 3.4e-34, bitscore:
                     107.3, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFYRKQLRIALRNCGFIDPENIEEYIAREGYFALADCLLNKQPT
                     DVIDIIKRSGLRGRGGGGFPTGLKWEFANKQQSDVKYVVCNADEGDPGAFMDRSIMEGD
                     PHSIVEAMCVCGYSIGSTKGLVYIRAEYPLAINRLKTAINQAREYGLLGDHILGTDFSF
                     DIEIRYGAGAFVCGEETALIHSMEGKRGEPTLKPPFPAESGYLGKPTNVNNVETLANIP
                     IILTKGADWFATIGTERSKGTKVFALAGKINNVGLIEVPMGTTLREVIYEIGGGIKGGK
                     KFKAVQTGGPSGGCLTEKHLDTPIDFDNLLSAGSMMGSGGMIVMDEDDCMVSVARFYLD
                     FTVEESCGKCTPCRIGNKRLLELLNKITEGKGTEKDLDTLATLGQVIKDTALCGLGQTS
                     PNPVLSTLDNFYDEYMEHVRDKTCRSKQCKSLLTYTISPERCIGCHLCAKNCPADAISG
                     LVRKPHVIAPDKCIKCGMCMARCKFNAILVC"
     CDS             7106..8935
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH-G_4Fe-4S_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_11"
                     /sec_met_domain="Fer4 (E-value: 6.2e-10, bitscore: 29.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.8e-05, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_4 (E-value: 4.9e-23, bitscore: 71.6,
                     seeds: 126, tool: rule-based-clusters)"
                     /sec_met_domain="NADH-G_4Fe-4S_3 (E-value: 4.6e-19,
                     bitscore: 58.4, seeds: 418, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRHVHGTLQIQRYSCLLKSITMEDKQITLQIDGHFITVPEGSTIL
                     EAATKIGINIPTLCHIDLKGTCIKNNPASCRICVVEVIGRRNLAPACATRCTEGMVVKT
                     STLRVMNARKVVAELILSDHPNDCLTCPKCGNCELQTLALRFNIREMPFNGGELSPRKR
                     EITASIVRNMDKCIFCRRCESVCNDVQTVGALGAIRRGFNTTIAPAFDRMMTESECTYC
                     GQCVAVCPVGALTERDYTNRLLDDLANPDKVVIVQTAPAVRAALGEEFGFPPGTLVTGK
                     MVYALRELGFDYVFDTDFAADLTIMEEGSEILNRLTRYLNGDKSVRLPILTSCCPAWVN
                     FFEHHFPDMLDIPSTARSPQQMFGSIAKSYWAEKMGIPREKLVVVSIMPCLAKKYECAR
                     DEFKVNGIPDVDYSISTRELARLIKRANIGFPLVLDSPFDNPMGESTGAGVIFGTTGGV
                     MEAALRSVYEIYTGESLKNVNFEQVRGLNGVRRATINLNGFELKVGIAHGLGNARHLLE
                     DIRNGHNEYHVIEIMACPGGCIGGGGQPLHHGNSEILYARANALYREDANKPLRKSHEN
                     PYIKTLYEEYLGKPLGEISETLLHTHYFNKSMD"
     CDS             complement(9035..9190)
                     /locus_tag="ctg3_12"
                     /transl_table=11
                     /translation="MFPFRGHGEEGIEGDHSIYFRYGDIEFGSDDALHLFGQVAVQVLR
                     FVQNID"
     CDS             10001..12229
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_13"
                     /sec_met_domain="Gly_radical (E-value: 9.4e-47, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1172.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLRNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             12245..12973
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.2;
                     E-value: 4.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_14"
                     /sec_met_domain="Radical_SAM (E-value: 8.3e-30, bitscore:
                     94.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLVRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(13001..13291)
                     /locus_tag="ctg3_15"
                     /transl_table=11
                     /translation="MRDEDTVGAHARGFNAISLGVCYEGGLDENGKAADTRTSRQKEAM
                     HRLVNELLQRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVKAETW"
     CDS             13325..13495
                     /locus_tag="ctg3_16"
                     /transl_table=11
                     /translation="MIPPTRKAPKAMGSVHILRREVAISTGSRAVNHNQTNLSHRPSPF
                     PSFSHYTLPYG"
     CDS             complement(13619..14116)
                     /locus_tag="ctg3_17"
                     /transl_table=11
                     /translation="MTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITSRS
                     TCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLITAA
                     HIIFRPGKTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAPDP
                     AA"
     CDS             14316..14546
                     /locus_tag="ctg3_18"
                     /transl_table=11
                     /translation="MYYPDQPFHICTYKKSELAHLYNPNVCLKVALQILRRWIVYNLPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             complement(14844..15326)
                     /locus_tag="ctg3_19"
                     /transl_table=11
                     /translation="MVVECHLFGEGIVVWCCRLFLFAGCPFLLLRLEEYRWLFHDDSCG
                     IGIEINIRIVREQASTADILSGSVDLNSAELGIKGSDFVISGMMEIFNFLNRFGQCPVR
                     PAYTYHDFQSHSFGTDESDAGVGTLFCQCEDACQCFLCLMVDVYHDVSQILDESCV"
     CDS             complement(15591..15821)
                     /locus_tag="ctg3_20"
                     /transl_table=11
                     /translation="MVGAAEVGVDQILNRLDGARIAQFVHLHPNAVFHHFVENMERFRL
                     LRVRFPSAIFHDMKHFVVACIVIFFDMLLNL"
     CDS             16386..16751
                     /locus_tag="ctg3_21"
                     /transl_table=11
                     /translation="LYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLT
                     HIRKPERFEKVHYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRY
                     TVFIIDTEQVKSNRLYE"
     CDS             complement(16883..16999)
                     /locus_tag="ctg3_22"
                     /transl_table=11
                     /translation="NNKAPACESRGFVRKKQKVCILTHLRFFEEEKGKGEGR"
ORIGIN
        1 acgtaaagtt atcataaagt tcaagagctt ccctacaata cttttccctt tcgtcgggag
       61 tttttgctgt cgtaatcata cggtaatatt cgaaacgggt cagttccttc ggattctttc
      121 tgtaaagttc tctaatctcg tcgtccgtca aagaacggaa gattgaataa ccataggtat
      181 attgcacctt tctcaattta ggcaaataag tagccgcaag ttccttgtag aaaggtttcg
      241 atttcaagac cccattcaac cggtaaggag tagctgtata ttgtttgatt aagtcctcta
      301 cttctttagc cagttccggc ttggagtttt ttttcagcaa ttcagctacc tccttccagg
      361 aggcaaccga tgcatccgat ttcacctcca acagtttacg tgtttccggg tccagttgtg
      421 ccagtatacg ttccagggcc ttatccgtac gcaattttgc cagacgaaga ttcgtcgcgt
      481 aagaaccgtc cggcgaagcc acccccgtaa tatgaaaact cttcaaagag gcatccgggt
      541 tcgtctcaat accacgcaat tcctgattca accggttcag ttccacctga ttttgtggat
      601 tcttatcatc caggtcggct ttacctacca ggaaggttaa gtttacctca cctttcgtat
      661 cccgcaactg catcacgggt ttcggaaggt atttctcgtc cgtcaggctg aaagcggaga
      721 atttatactc caagaagcga agcgggttga ccgttccgcg tgcaatggag aaagagtcac
      781 gataaatgat attccggtaa ttttccatcg ccagatgcac atctgcacgg tagtcatgtt
      841 gcagatattc tatatagata gaatcatggt aagcaataat atcccccttg cgtgaagaag
      901 tagttttcac acggatgtaa tcgtgcaaag gatctttatc catatcataa tcgtacattc
      961 gattttgcgt tgtattataa gtatccccgt cgaatacaac aggacgcatc aacagacgct
     1021 ttttcagtgt cacatcataa atggaaggct gcaataccaa gcgacgatgt gagttaaaca
     1081 tctccttagg caccgggaca cgagttttca gatggaaata attacctttg atttcgatgt
     1141 ccgtaggttc cggaatcact ttgtccttca ctttggaagt aattgtaact tcgtccagtt
     1201 cgatgacggc atctttcaat actacattca gaatctgctt tcctgccacc ttcactgttt
     1261 tgtcttcata accgacacat gtaaacttca acgagccgtt tttctcaacc aagacactgt
     1321 aacggccatc ctcgtcggac atttctatac gttcgtcatt gaccggattc aacacattta
     1381 cattcggaac actttttccc tgcgggtttg tgatatgccc ctgcacgcgg atccgttggg
     1441 cggatacatt cataccgacg aacatcatcg ccacgagaag tatacctgtt aatctatcac
     1501 gtttcaaatt gattttcatt ctcttttctg actagctaat gttcgttatc gaataatata
     1561 aacaaaggat acccccagtt tgacaggtgc aatggtggtc ttactatcgt tgaccgcacc
     1621 cggtttcgga gtacccttat catacttaaa ctgacggtag cgcaacacac ccactccggc
     1681 agttgcttcg atgttccaat gatcgcccag cacccatgcg tatccatagg tcaaaccggc
     1741 ggcgtatgca tcgcctttgt gatgcacatc ttttaccatc atatcaaaat tattcacgaa
     1801 agcggtgatt ccaagaaaat gactcaccat cggacgattt agccagtaac gaacttcagg
     1861 ctgaaaatgc gtgaaagtcg ttttaaagtt gtctgtactg attgggttcg cagcaatccc
     1921 catgttcaag gagacatgac tacccaatac aaattctgct tctacattcg gactggcggt
     1981 cagccaaccc aatgcatttg tctttacagc cacccgttgt gcgtgcacat gtacaccaca
     2041 acataataac agaaatgata acgcagctat taccctgcga ccatttctca tcacatatac
     2101 catcatttat ttcccactaa atatttccca ctaaatattt acccacaaaa aaagggctta
     2161 ctgtccattt tatatactac ttggacagaa agccacaaaa ttagaaaaaa tatagtatta
     2221 aaaacgttta aacacgcttt ttttgttttt tattgcaaca atttccatct taggccataa
     2281 tataccatac tacggataag atatacaatt tttctttatt accaatgaaa catcagatac
     2341 gcaacaacat aggctccgac gaagcatcgg attttatctt cttatcgccg ataacaaccg
     2401 tacagggagc agaagaaata atataccatt tcccttcttt cttttcgagc aatacattag
     2461 cggcattgtc ggtctgaatc attaccccgg gtgcaaccaa ttgggtccca ttccctaaaa
     2521 acaacgtccg gtttcctgca tattcattgc tgataacagc ataatccgct ttcactttca
     2581 ttccttgata aatagcggtt tgtgcagcat cagatagaga gaagatatga tctatacgtc
     2641 cgtttttgct tttcacacag ataccggcaa agtcttccaa acctgctcct tctgcatcaa
     2701 agtaagagac ggactgaata gcagacggtt cctttttcgt actcggttca tatatcgaga
     2761 caaaaggacg attccaagct tctccatgct gacgggcaac aaatgtcagc gtcggctgct
     2821 cctttatatt atagggcata ttcggtgtac ggcttagccc ttcggtcatt ggcgccaaag
     2881 ccgtaaagac ttcacgatcc ggttcgcctt tcatccaaag attcatgtat atatcatcgc
     2941 cgtccttatc tttcatatct atggtgaaag ttgccttgac atccttattg gttgcagcca
     3001 ctttcttatc atataaatag gaataagcgt aaagatgtgc gcctgcaaag gcgagttctt
     3061 ccgtagactg gagattcagg tcgctgccat ctgctgccgt caatgtcaaa gtctgtccaa
     3121 ggttgtgata gaagtaatcg tgcatcttat cgcctccttt ctctttccgg ctgcggaata
     3181 catcgacata ataccccgtc tccgccccgg tagtgacaat actcatcata cgggtctgat
     3241 ccgccctgct ttccggttca cgaaaataaa ggttactgta agtaacggac gtaaatgctt
     3301 tgcccggttc cgctgatgcc gggaaacagg aaagcaaatc aaaagaatga ttacttttca
     3361 tcaccggata gctcgatatt ccatccacac aaactgtatt atgactgggg aattgagaat
     3421 aatattccgc ataatccagt ccgctataca ggaaaagccc gatacctgca tccggcccca
     3481 gtacgtatcc ttttccataa agttccatcg aaatgccgtt agcgtgcatg tggttccctt
     3541 cactgccatt caacgaaatc atcaaactgt tgcgcggatg cataccgttg cgctgtacca
     3601 gccatgacac attgggagca taaaacaaag gagaaacata atcttctatc tttcccggct
     3661 gcactttggg atttagcgcc agcggtttat cttcaaagaa agaattgaca gatacacgca
     3721 cattcttctt ttctgtttta tcatttccca aatccgggtt caggcatttc aataaagccg
     3781 tgaaatagtt ttcctgttct ttcttcccgt tcgcctgtgc attctgtatc atacggataa
     3841 agaagttcgt actcaaatat cccggatgcg tatctccaaa gccacaaatc atacggttgg
     3901 gaaacagata ttggggagtg gttgctaccg ctttcgacaa tacaggcatt gctttcacca
     3961 aatcatattg cagattcgta tcaaactgat tcacaaaatt ggcataatca ttgattacca
     4021 cactgctata tcccggacat tctgcccaaa ttcccgtatt tatatcgaaa ccataatctg
     4081 ccaattgcgt cagactccat tggcggatgc tggaacggtt catcacatag tcgatataat
     4141 attcacgtcc ttttccgtcg gcatattctt tattgtcttc caataccaat ccgacattca
     4201 taataaaccg tgcctgtagc aaattccagt tgttatgagg tacaccgttc gctatgatat
     4261 tatccgccca tttcttaaaa gctccggcgt agatttccat tttatccggg taattggcct
     4321 ttagataatt atatagaaaa tcgtataaag ggacagcgat atggagtgcg tcttcatgga
     4381 tgacttcgaa agaagtcaat cctaccaatg tttgctgatg gccgtgattc aggtcgatgg
     4441 gcacgtttct ataataaata cctgtcatat atgtatcaaa gacccccgcg gcaagtttag
     4501 cgaatttctc ttcatccgtc atccaataaa ggaaagcggc atcacgggca attcccagga
     4561 tttcgcagtt caggctttca atattccggc ctgttttgga tgggtgtaca ctctccatag
     4621 gacggtcggg aagtgcatta ttgcagaaag tgacattccc atcctcatca tcataaggaa
     4681 cgacatccgc caatttggga cggccgtggg tagcagctgt gccacgggtt cctgtgtaac
     4741 gcacagtggg ataaggagct ttttcaccac ctgcatggtc gaacgtttca cctttcacat
     4801 atacttccgt ggcatgagac ttccagtaca ttgccaaacg agacagcaac cacgccggtt
     4861 gagcatccgt caggttcgta tatacttccg tccgttcctt caatttattg aaaacatctt
     4921 tcgcccattc ttctttttta atcagcttcc atgtttcctg ctttcccgcc ggagtagtca
     4981 gtacccgcgg atgtgtctgc ggcatctttt ccggcaaagg aatctcttgt ccggatgcgc
     5041 tgttcagaaa ggatagaaaa catagtccaa gtaaaattcg tctcatactt caattttctt
     5101 tttttaggtt tgatacctat taaatacgaa gatagagatt tatttaccta aatcctccgt
     5161 caaagaacaa ttttatttgt acgagactac gctgttattt caaacaaaga attatatttg
     5221 caaaaaaccg actaacaatt ctgatactta tgaaaatttt atctatccat gatttggcaa
     5281 caatcaggaa gagagcagag cacaatcttt cattgcgcga agaaagtaat gaaaaggtga
     5341 ctgaaaagtg ttacggactg gcatccggtg cgcaacatct tcagattctg atctgcggtg
     5401 gtacaggctg taaggcatct tccagccagg gtattacaga caatcttcta aaagccatca
     5461 aaaagaacga aatcaccgat aaagtagaag tcatcaccgt aggctgtttc ggcttctgtg
     5521 aaaaaggtcc tatcgtgaaa attatccccg ataatacctt ttacacccaa gtcactcccg
     5581 aagatgcgga agaaatcatc aacgagcata tcatcggagg acgaagaatc gaacggttgc
     5641 tgtatgtaga tcccaaaacg gaacataccg tcagcgactc caagcacatg gatttctacc
     5701 ggaaacaact ccgcatcgca ttgcgtaact gtggttttat cgatcccgaa aatattgaag
     5761 agtatatcgc ccgtgaagga tactttgcat tggccgattg cctgcttaac aaacagccga
     5821 cggacgttat tgatattatc aaacgttcgg gacttcgcgg acgtggtggt ggcggtttcc
     5881 cgacgggact gaaatgggaa tttgccaaca agcaacagtc agatgtcaaa tacgtggttt
     5941 gtaacgccga cgaaggagat cccggtgcat tcatggaccg ttccattatg gagggcgacc
     6001 cacattcgat tgtagaagcg atgtgtgtct gcggttattc cattggttcc accaaaggat
     6061 tagtatatat ccgtgcggaa tatccgttag ccatcaaccg actgaaaaca gctatcaatc
     6121 aggcacgcga atacggatta ttgggagatc atatcttagg aacagatttc agtttcgaca
     6181 tagaaatacg atacggagcc ggagcttttg tatgcggaga agaaactgcc cttattcatt
     6241 cgatggaagg aaaacgggga gagccgactc tgaaacctcc cttccctgcc gaatccggtt
     6301 atctgggaaa accaaccaat gtgaataatg tggaaacgct tgccaatatt cccattattc
     6361 taaccaaagg agccgactgg tttgcaacga ttggcacaga acgttccaaa ggaaccaaag
     6421 tgtttgctct tgccggaaag attaataatg tcggactgat cgaagtgccg atgggaacta
     6481 ctcttcggga agtaatctac gaaatcggag gaggcatcaa aggcggaaag aagttcaaag
     6541 ctgtacaaac aggaggaccg tcaggcggct gtctgacaga aaaacatctg gacactccca
     6601 ttgactttga caaccttctc tcggccggtt ccatgatggg ttcaggaggg atgattgtca
     6661 tggatgagga cgactgcatg gtatccgtag cccgctttta tctggatttt acagtggaag
     6721 agtcctgcgg gaaatgcaca ccttgccgca ttggaaacaa acgtctgttg gaactactga
     6781 acaagattac agaaggaaaa ggcacagaaa aagacctgga cacacttgcc actttgggac
     6841 aagtcatcaa agatacggcc ctctgcggac tgggacaaac ctctccgaat cccgttttat
     6901 ccacattgga taacttctac gatgaatata tggaacacgt acgggataag acttgtcgtt
     6961 ccaagcaatg taaatcacta ttaacgtata ccatcagtcc ggaacgttgc attggttgtc
     7021 atctatgcgc caaaaactgt ccggcggatg ctatcagcgg gctggtgcgc aagccacatg
     7081 tcattgctcc cgataaatgt atcaaatgcg gcatgtgcat ggcacgctgc aaattcaacg
     7141 ctattcttgt ctgctaaaat cgattactat ggaagataaa caaatcaccc tccagataga
     7201 cggccatttc atcaccgtcc ccgaaggaag taccatcctt gaagccgcca cgaaaatcgg
     7261 catcaacata ccgaccctgt gtcacatcga cctgaaaggc acctgcataa agaacaatcc
     7321 tgcttcctgc cgcatctgcg tggtcgaggt tataggacgc cgcaatctgg ctcctgcctg
     7381 cgctacccgt tgcacagaag gaatggtagt aaaaaccagt acgctacgtg tgatgaacgc
     7441 acgcaaagtg gtagccgaac ttatcctgtc ggatcatccc aacgactgtc tcacctgccc
     7501 caaatgtggc aattgcgaac ttcagacatt agcgctacgc tttaatatcc gcgaaatgcc
     7561 tttcaatgga ggcgagctct ctccccgcaa acgggaaatc actgcctcca tcgtgcgcaa
     7621 catggataaa tgtattttct gtcgccgctg cgaaagtgtc tgtaacgatg ttcagacagt
     7681 cggtgcgctc ggtgccatcc gtcgcggatt caacacgacg atagcccctg cctttgaccg
     7741 aatgatgacg gagagcgaat gtacctattg cggacaatgc gtagctgtct gtccggtggg
     7801 tgcactgacc gaacgcgatt atacgaaccg cctgctcgac gacttagcta acccggataa
     7861 agtggtgatt gtgcaaacag cccctgccgt acgtgctgcc ctgggcgaag aattcggttt
     7921 tcctcccggc acactggtaa ccggaaaaat ggtttatgcc ctgcgtgaac tgggattcga
     7981 ctatgtattc gatactgact ttgccgccga cctcaccatc atggaagaag gatcggaaat
     8041 actaaaccgt ctgacgcgct atctcaacgg agataagtcc gtacggttac ctatcctgac
     8101 ctcctgctgt ccggcatggg tgaacttctt cgaacatcac ttcccggata tgctggacat
     8161 tccatccacc gcccgttcac cgcaacagat gttcggttct atcgccaaat cctattgggc
     8221 ggaaaagatg ggaatcccta gagaaaagct ggtagtcgta tccatcatgc cctgtctggc
     8281 aaaaaagtat gaatgtgccc gcgatgaatt taaagtgaac ggtattcccg acgtagatta
     8341 ttctatttcc acccgcgaac tggcacgact gattaaacgc gccaatatcg gcttcccgct
     8401 ggtactggac agcccgtttg acaaccctat gggtgagtcg accggtgccg gcgttatttt
     8461 cggtacaaca ggtggtgtaa tggaagccgc cctccgttct gtttatgaaa tctataccgg
     8521 agaatctctg aaaaatgtaa acttcgaaca agtacgcgga cttaacggtg tccggcgtgc
     8581 taccatcaac ctaaacggat ttgaattaaa agtaggcatc gcacacggac taggcaacgc
     8641 ccgccatcta ttggaagata tacggaacgg gcacaacgaa tatcatgtaa tcgaaattat
     8701 ggcttgcccc ggaggttgca tcggaggagg cggacagccg ttgcatcacg gcaactcgga
     8761 aatattgtat gcacgcgcca acgcactcta ccgcgaagac gccaacaagc ctttgcgcaa
     8821 atcgcacgag aatccgtaca tcaagacctt gtacgaagaa tatctcggca aaccactggg
     8881 cgagatatcg gaaacgctat tgcacacgca ctatttcaac aaatctatgg attaacttta
     8941 aacgaagagt attatgtcag atataaaact agcctgcgat gtggcagaac aagtccgaac
     9001 gatttgcgac aagcacggaa acaacccggg cgaactaatc aatattttgc acgaagcgca
     9061 acacctgcac ggctacctgc ccgaagagat gcaacgcatc atcgcttcca aactcaatat
     9121 ccccgtatcg aaagtatatg gagtggtcac cttctatacc ttcttcacca tgaccccgaa
     9181 agggaaacat cccatctccg tctgcatggg tacggcatgt tacgtgcgcg gctccgagaa
     9241 gttactcgaa gaattcaaac gcgtactagg catcgaagtc ggcgaaacca caccagatgg
     9301 aaaattctca ttggactgcc tgcgctgcgt aggtgcctgc ggactggctc cggtagtgat
     9361 gattggcgag aaagtgtacg gaagattgca accgatagat gtgaagaaga ttatcgagga
     9421 gttggaataa atgtccggaa taaaaaagtg gctgctttga aaaatcaagg cagccgcttt
     9481 caaacatttt tttaacaaca aacaaaaaag cggagagaac gagattcgaa ctcgtgatac
     9541 cctttagggg tatacacgct ttccaggcgt gcctcttcaa ccactcgagc acctctcctt
     9601 attttccaat aaaaacagac aatggaaata tattttccac aaaagaaata gcagcttaaa
     9661 agctgctatc ctagcggaga gacagggatt cgaaccccgg gtacctcgcg gtacaacggt
     9721 tttcaagacc gccgcaatcg accactctgc cacctctcca aaacttcctt ttcagaagtg
     9781 ctttttgtta aaagcggtgc aaaggtacga atatatttta aacttgcaag agttttcaca
     9841 aaaaaaaatc acgaacatca tttccaaaga atagctatat ctaggtattt tatgttgaaa
     9901 agcataaaat acagcatatt tatgctgatt atatgaaaaa acgttgtaac tttgtgcgct
     9961 ctaaagaaaa ggataactac aacctctaat tttatcattt atggaattaa ataagatctt
    10021 taaagacggt ctttggagca cagaaatcaa cgtaagagat ttcgttagtc acaacatcac
    10081 tccgtattat ggagatgctt ctttcctcga aggacctacc gaacgcacta aagctgtatg
    10141 gaaccgctgc ctcgaagcac tggcagaaga aagagccaat aacggagtac gctcactgga
    10201 taatgtcacc gtctcaacca tcacttctca taaagccgga tatatcgaca aagaaaacga
    10261 actgatcgtc ggtctgcaaa cagacgaact tctgaaacgt gcaatcaaac ctttcggagg
    10321 tatcaacgtg gtgagcaaag cctgccacga aaacggcgtg gaagtggacg accgtgtaaa
    10381 agatatattc actcactacc gcaagacgca caatgacgga gtatttgacg tatataccga
    10441 agaaatccgt tcgttccgtt ctctgggatt cctcaccgga cttcctgaca actatgcccg
    10501 cggacgtatc atcggcgact accgccgtat ggctctctat ggtatcgacc gactgattga
    10561 ggcaaaaaaa gaagatttgc gtaaccttac cggtccgatg accgaagccc gcatccgcct
    10621 gcgcgaagaa gtggcagagc aaatcaaggc attgaaagac atgaaagtaa tgggcgaata
    10681 ctacggactc gacttgagcc gtcctgccta caccgcacaa gaagcagtac aatgggtgta
    10741 catggcttac cttgctgccg taaaagaaca agacggtgct gccatgtcac tgggtaacgt
    10801 ctcttcgttc ctcgacattt atatggaata tgaattgagc aaaggaacta tcacagaatc
    10861 tttcgcacag gagctgatcg accagtttgt catcaaactg cgtatggtgc gccacctgcg
    10921 tatgcaatct tacaacgaca tctttgccgg cgacccgaca tgggtaaccg aatccctggg
    10981 cggacgcctc aacgacggac gcaccaaggt gacaaagact tctttccgct tcctgcaaac
    11041 actctacaac ctcggccctt caccggaacc gaacctgact gtattgtgga gcccggaact
    11101 gccggaagga ttcaaagaat tctgcgcaaa agtatctatc gacacttctt ccatccaata
    11161 tgaaaacgac gacctgatgc gtgaagtgcg ccagtctgat gactacggaa tcgcgtgctg
    11221 cgtatcttat caggaaatcg gaaaacaaat ccagttcttc ggcgcacgtt gcaacctggc
    11281 taaagccctg ctgcttgcca tcaacggcgg acgttgcgaa aacaccggta cggtaatggt
    11341 gaaaaacatc cccgtactaa ccagcgacac actgaacttc gaagaagtaa tgagcaacta
    11401 caagaaggta ttgacagaaa tcgcccgtgt ttacaacgaa gcgatgaaca tcatccatta
    11461 tatgcatgat aagtattact acgaaaaagc ccaaatggct cttgtagata ccaacccacg
    11521 catcaacctt gcttacggtg tagccggact ttctatcgcc ctcgattcac tgtcggccat
    11581 caaatatgcc aaagtaaccg cacgccgcaa cgacatcggt ctgacagaag gtttcgatat
    11641 tcaaggcgaa ttcccttgct tcggtaatga caacgacaag gtagaccacc tgggtgttga
    11701 cctggtctat ttcttcagcg aagaattgaa gaaacttccg gtttacaaaa atgcccgtcc
    11761 tactctgtct ttgctcacca tcacttccaa cgtgatgtat ggcaagaaga caggtgctac
    11821 tcccgacggc cgcgccaaag gtgtcgcttt tgctccggga gccaacccta tgcacggacg
    11881 tgacaagaac ggtgccatcg cctctttgag ttccgtagcg aaattacgtt accgcgactc
    11941 acaggacggt atcagcaaca ccttctccat cgttccgaaa tcactgggag ctactgaaga
    12001 agatcgcgta gaaaatctgg tgacaatgat ggatggttac ttcaccaaag gcgctcacca
    12061 cctgaacgtg aacgtactga accgtgaaat gctttacgac gccatggaac atccggaaaa
    12121 atatccgcaa ctcaccatcc gtgtttccgg ttatgccgta aacttcgtga agttgagccg
    12181 cgaacatcaa ttggaagtta tcagccgtag cttccacgaa cgtatgtaat cagatctact
    12241 caatatgacg ataaacgtac attcatacga aagtatggga acattcgacg ggccgggctt
    12301 acggctcgtc gtttttcttc aaggatgcaa tttccgctgc ctgtattgtg ccaatcccga
    12361 cacgatagcc ggaaaaggag gtacacctac cccaccggaa gaaatcgtcc gcatggctat
    12421 gagccaacgt ccttttttcg ggaaacgcgg aggagtcact ttctccggag gagaacctac
    12481 gtttcaggcc aaagcactag tccctttagt gcgtgaactg aaagaaaagg gaatacatgt
    12541 atgcatagac agcaacggcg gtatctggaa cgaagaagta gaagaacttt tcaaactgac
    12601 ggatcttgta ttgctggata ttaaagagtt caatccggca cgccatcaag cactgaccgg
    12661 aagaagtaac gagcaaacca tccgcacggc agcatggctg gaagaaaacg agaaaccttt
    12721 ctggctgcgt tatgtattag tgcccggata cagcgatttc gaagaggata tccgccgctt
    12781 gggagaggct ctgggaaaat ataagatggt gcaacgagtg gaaatcctgc cttatcatac
    12841 attaggcgta cataagtatg aagcgatgga gcaggaatac aagctgaaag acgtaaaaga
    12901 aaataccccc gaacaacttg aaaaagccgc ggaggtattt aaagagtatt tcactactgt
    12961 ggtggtcaat taaccaccac agtaataaat aggataaaaa tcaccatgtc tctgctttca
    13021 cctcgaaaca gggacactct ttgatccgct cccaagggtc aacaattcca ttataattgg
    13081 tgtcaggact caagtcccga tgaccgacca cctttgcatc cggataacgc tgcaacaact
    13141 cgtttaccag acgatgcatc gcctctttct ggcgggaagt acgcgtatct gctgcctttc
    13201 cgttctcatc cagcccgcct tcatagcaca ctcctaaact aatcgcatta aaaccgcgtg
    13261 catgagcacc caccgtatct tcatccctca tcggctctat ctgtcccgac ttgcggatat
    13321 aataatgata cccccaacaa gaaaagcccc gaaagcgatg ggcagtgtcc acatccttcg
    13381 ccgtgaagtc gcgatcagca cgggtagcag agcagtgaat cacaatcaga ctaatctttc
    13441 tcatcgtcct tctccctttc cgtcgttttc acattacaca cttccttatg ggtagcattg
    13501 aagcgcacct ctctcacaat tctgttccgc tttctttttc cgaagaaagg cacaaggaac
    13561 ataattacat ccaaaatctt agttacaatt tctttcattt gattcaatat taaagttatc
    13621 atgctgccgg atccggagct tctccgcttc caccaccgtc tgaaccgcca ccggaacctt
    13681 tgtcatcatc ttctccttca ttgccgctac cgcccgtttg ggccaccgca cgcgtcgtta
    13741 cctgctggta gctaagaatc ttcgtgatgt ccgccaacgt ctttccggga cgaaaaataa
    13801 tatgggcagc cgtaatcagc gaacttgaaa actccttgac cgacacagct ccttcactgt
    13861 tcaacccgat ctgcaaactg cccaaatcac ccaaccggac tattcttccc gctttcaacg
    13921 cacgcttcgc ctcataaaga atacccgaaa tggcggcacg cacatctgtc tccgtacagg
    13981 tagaccggct ggtgattccc tcgcacaact cttcaaaatc caactctccc gaagcctgtg
    14041 cctgcgcgta atactttgcc gactcatcct ttttggcagg attcttgcgc ggcactactg
    14101 aataagttac tgtcattgcc ataataaaat aattttaaga tttcacacat ttcgaacgcg
    14161 ttccttattt gttaacgaca taaagataac acatttttca ccctccggat tccccaacga
    14221 agtttcctga tactctatga ataataatga cgttattctt ttattaaacc attaattttc
    14281 agtaacttta tagcataaac caaatatcat tcatcatgta ttatccggat cagccgtttc
    14341 atatctgcac ttataaaaag tcggaactag ctcatcttta caaccccaac gtatgcctta
    14401 aagtagcctt acaaatacta cgtcgttgga ttgtctacaa ccttccgctc ctgcaagaac
    14461 tcgaacaaga aggctatcgt gcccgcaacc gccttctctc tccccggcaa gtggcaacga
    14521 tcatacgcta tttgggagaa ccctaggaac ttaatcaaaa aaacgaaaag ttccattcta
    14581 ttattttaca aacaaatttc tttgcaaccg caaattaaaa agaacaaacc aacatggagc
    14641 attttaccat ctttcaagac ttttaccgcg tcatagccga aatgacagaa gaagaaatcg
    14701 tatcggccat cagcaacggc acataccggg aaacagtgga ggacgtgcgc cgaatcttcg
    14761 cggaacaagg cgagaaagca gcaaacgaaa agaaaataga actaccggaa atcacctttt
    14821 cagccaacta ccggggagga cgttcaaacg caactctcgt caagtatctg ggatacatcg
    14881 tggtagacat cgaccatcag acacaggaag cattggcacg catcctcgca ctggcaaaaa
    14941 agtgtgccca cacccgcatc gctttcatca gtcccaaagg aatgggactg aaaatcgtgg
    15001 tacgtgtatg ccggacggac gggacattgc ccgaaacgat tcaggaaatt gaagatttcc
    15061 atcatgccgc ttatcacaaa atcgcttcct tttatgccca gctctgcgga gttgaggtcg
    15121 acacttccgg acaagatgtc agccgtactt gcctgttctc ttacgatccg gatatttatt
    15181 tcaatcccga tgccacagct gtcatcgtgg aacagccacc gatattcttc aagtctcaaa
    15241 agaagaaaag ggcatccggc aaaaagaaaa agacgacagc accagacaac aatcccctca
    15301 ccgaacaagt ggcactcaac taccattcct cgcacgcttc cttaatggtg actctgaact
    15361 attatcacaa taaatccgaa aagtacgtca ccggcaaccg gaacaactac ctgcattgcc
    15421 tggcttgtat gtacaatcgc tacggcgtcc cccaggaaga ggcggcagct tttatcaaga
    15481 gccagttcac cgatcttccc gcggatgaaa tggacgcact gatcgggagt gcttacggac
    15541 acaatgagga attcgacacc cgcaagctga atagtacgca gaagcgaata ttacagattg
    15601 agcaacatat caaagaaaat tacgatacac gctacaacga agtgcttcat atcatggaat
    15661 atcgcagaag gaaaacggac acggagcaac cggaaccttt ccatattctc gacgaaatga
    15721 tggaaaacag catttggatg gagatgaacg aactgggcta ttcgtgcacc gtcaagacga
    15781 ttcagaatct gatctactcc gacttcagca gcacctacca tcctattcgc gagtatttag
    15841 actcgctgcc tgaatgggac ggaacggatt atatcggtat ccttgccaac agcgtgcata
    15901 ctagtcacca gaaattttgg gtagaatgtc tggaacgtta tctggtggga atgtgcgctg
    15961 ccgccacgca agacgatgtg gtgaaccaca ctgttttgtt gctttgcagc gaaatacaga
    16021 acatcggaaa gactacgttt atcaacaacc tgctgccgcc cgaattgcgc gcctatcttt
    16081 ctaccggtct tattaacccg aacaacaagg atgatctggc caaaatagcg caggcaatgc
    16141 ttatcaatct ggatgagttt gaagggatga acggacggga actgaatatc ttcaaggatt
    16201 tggttacccg caaagtaatc agcatccgcc tgccatacgc gcggcgttca cagaacttcc
    16261 ctcacacggc ttcttttgcc ggcacatgca attatcagga agtgcttcac gacaccacag
    16321 gtaaccgccg ttttctctgc tttcatgtca actcgatgga gtttatcaaa ataaactacg
    16381 cgcagttgta tgcacaaatc aagtatctgc tcaacaagcc ggggtatcag tattggttca
    16441 cccaatcgga aaactcacgg attgaagaga acaacgagga tttcattttc cactcaccgg
    16501 aagaagaact ggtgttgaca catatccgca aaccggaacg tttcgaaaag gtgcattatc
    16561 tgacggtcac tgaaattgcg gaattgattc gcgaacgaac ggggtatcaa tattctcacg
    16621 gaaccaaagc ccaactagga aaagtgatgt ccaaacacgg cttcgaattt cataagggaa
    16681 aaaacgggag aagatacact gtattcatta ttgatacgga acaggtgaaa tcaaacaggc
    16741 tatatgaata agatttcatc tccttcgcac gcaaaaaggt gagggttggt gagggtactt
    16801 ttgcaacttt tcatttttat atttcttatt tctattcttc tattttcttc taaaaaaaaa
    16861 tacgaatgtt agaaatttac cctcacctac cctcaccttt tcctttttct tcctcaaaaa
    16921 aacgaaggtg tgtcaaaatg cacaccttct gttttttacg cacaaagccc cgactttcac
    16981 aagctggggc tttgttatta
//
