LOCUS       c00052_gnlPro..        24557 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LFEPMIAA_52.
ACCESSION   c00052_gnlPro..
VERSION     c00052_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 23:08:12
            Original ID  :: gnl|Prokka|LFEPMIAA_52
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 12988
            Orig. end    :: 37545
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24557
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[22988:27545]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14557
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24557
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24557
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(477..1271)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_14"
                     /sec_met_domain="F420_oxidored (E-value: 4.2e-14, bitscore:
                     45.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPIVFIGAGNLATNLAKALYHKGFRIVQVYSRTMESAR
                     TLAEKVEAEYTTDLQEISKDAKLYIVSLKDAALVDLLPQITEGKQNSLLVHTAGSIPMS
                     IWEGYAERYGVFYPMQTFSKQREVNFQEVPFFVEAKRPEDVELLKAVAATLSEKVYEAS
                     SEQRKSLHLAAVFICNFTNHMYALAADLLEKYNLPFDVMLPLIDETARKVHELAPRDAQ
                     TGPAVRYDENVMNNHLAMLVDSPALQEIYKLMSKSIHEHHQL"
     CDS             complement(1279..1614)
                     /locus_tag="ctg52_15"
                     /transl_table=11
                     /translation="MGAAKASNSKDTYLATAVTFIVIGALYLIDKLIHFSTIGLPWVMN
                     KDNMLLYASICFLIFKRDKSIGFVLLGLWLVMNISLVISLLGSLSGYLLPLTLLIVGII
                     LFWFAKR"
     CDS             complement(1617..2171)
                     /locus_tag="ctg52_16"
                     /transl_table=11
                     /translation="MKPENNMENFSELIKNRRSMRKFTDEELTQDQVVTLMKAALMSPS
                     SKRSNSWQFVVIDDKEVLKELSHCKEQASSFIADAALAIVVMADPLASDVWIEDASIAS
                     IMIQLQAEDLGLGSCWVQVRERFTATGMPSDEFVHGILGIPLQLQILSVIAIGHKGMER
                     KPFNEEHLQWEKIHINKFGGK"
     CDS             2334..2558
                     /locus_tag="ctg52_17"
                     /transl_table=11
                     /translation="MKKRITQDDYIKANRKASREAEIEMYGHPICHKRVHQSKKVYNRR
                     KIKAADKKLPYFFVFKIASLSSRHSDTIQ"
     CDS             complement(2647..3189)
                     /locus_tag="ctg52_18"
                     /transl_table=11
                     /translation="MIEEILAYNKQFVENKGYESYITNKYPDKKIAILSCMDTRLTALL
                     PAALGIKNGDVKMIKNAGGVISHPFGSVIRSLLVAIFELGVEEIMVIAHSDCGACHMHS
                     EVMLEKMKARGINPDYIDMMRFCGVDFHSWLDGFEDTEKSVRGTVDFIVRHPLIPSDVT
                     VYGFIIDSTTGELTRIV"
     CDS             complement(3299..5323)
                     /locus_tag="ctg52_19"
                     /transl_table=11
                     /translation="MKSTIYKIAALTFAVASMSACSLDEYNPSQKTGDEILATFDGLKG
                     LQSYCYSSLYGQLFSVYDFLSVAEGGTDCWITPAGNPDYAKQVIYYDGLATNTNATNKL
                     FGQAYSMIGNCNAVVNRAELLTDGNEKDITTLVAEARCLRAFYYSILVNTYGNVTLTLE
                     ESSQDPILTPQRNSIEELYTQIIDDLKFAANNLEDTPYDNNRARVTKKTALGLLARVYA
                     QGGGEYGLTEEGVSYWQRAKEVAEDMILAYGDCLYDDVEDVWAPANNRNNKEALFIAAG
                     PDATNLENWNAGTQCNNNFTYMYPKPNTLTIYPTPDNQNYWYGRTNNNTLAPSKYLLDC
                     FDADYDKRWEVTFTTAFVQFSAVQSGGSYLFTNKKQTLDDGTKPKIGTKHGVNDNISSF
                     TILTQNIIDTYGLDAKFHNEYIYPYGDLNYTYYDGTWAPKMIAKVWPKGENSGDPSKLQ
                     EVKNPYVIPYPVAEDDDRICFYLSKERLSDAEKAKRRYYVINIDDLFDNGQYRKTDIKV
                     TNDKNMYPGFNKYNWLSEDSYSSNLQRKTGDVFIMRMAEVYLIAAEANQQLGNGGKAAE
                     YLNVLKKRAARNDASYNAMKLSNATQNDVMDEYARELCGEYQRWVLMKRHKDSFKQRLA
                     VGNPRAAENFDENKHYLRPISFNFLSQIDNAEEYGNNGY"
     CDS             complement(5348..8587)
                     /locus_tag="ctg52_20"
                     /transl_table=11
                     /translation="MRCNAFVEAWKNHHRRASMILGLSLLSAPLSYSVYAEDGVSNTMV
                     QVVTQTKTVKGTIIDESGEPLIGVSIVVKGTSTGTITDFNGNFSIDLPAGRKELVISYI
                     GYKEQTVTVTGNGPVNVKMVSDTQALDEVVVVGYGTMKKRDLTGAITSVKSEDVVMNPS
                     SNPMQALQGKVAGLDITRESGQAGSGVKMQLRGNRSFQKDSGNPLFIIDGMPGDYSTLN
                     PNDIESIEVLKDASSTAIYGSSGANGVILITTKGGKEGKAIVNFNAYVGVNGWSRTPEM
                     RSGESYIQTLRDASVGAGDGRWSSVADDKNLFTTDAEWSAHQNGQYIDWVDALLKTSVT
                     QNYSVSVAGGTEKTKAYFSLNFSNEDGQFAQDSYKLYSSKIRVDHKIKKWMKVGIDAQL
                     SYVHQNKADSDLQTLMASNPLGSLYNEDGSINPQPVADPSSTVYNYLLNEDKSLYRNQA
                     QNLKVYFNPYLEITPLKGLTFITRAGASLGYSRSNTFTGEGSVQWYKANQTADGIKAQV
                     KDNRSYNYKWENILTYNFQIKKVHDITLTAVTSWNHNRSDVTTLYQKGVSDNKFLWHNI
                     LDGNSATSGSTSYSMSKGMGYVGRLNYSYMGRYLFAASVRHDGSSRLAEGNKWDTFPAF
                     SLGWRISDEKFMESTTNWLSNLKIRFGYGVTGSTAGIDPYSSAASLDATAVNMILGGVL
                     TPIYKFSQNIPNYLLTWEKSYNTNIGIDAAFLNNRIDVSMEYYNTKTKDVIWNKALPVI
                     NGAFSPDGGPKANYTTNLNMCETSNKGFELALNTRNIITKNFIWSSSVTFNHNKEKITK
                     LSGGDSDVLNNGDTGYALALGEAINSYYHYKLDGVWQKGEETDAAVFGAAPGDLKINIP
                     NLVKESDGRFYKIDEETGSAAVDENGNVIYYTSDNKYTPSDADYQILGHNSPDWSLGFQ
                     NNFTWKDFDLSVFVYARYGQMFAYDMLTSYDPKGIRNFPTYFNYWTENNPSNDFPAANA
                     NKGLEQYTGYYALRYVDGSFIKIKNITLGYSLPKSILKSAGIEKCRFYATITNPFVFAK
                     SHLLKDYDPEMNGSLKYPLTKQFVFGVNVTF"
     CDS             8827..9825
                     /locus_tag="ctg52_21"
                     /transl_table=11
                     /translation="MPLKLTTYYHGKDIPELPGKNAFHSKELFQIYEATPGYTPLLIVA
                     TEDGRPMARLLAAIRKAKKWLPSSLVKHCVVYSEGEFLDESLSTNKEKAEEVFGDMLEH
                     LTQEASRSCVLIEFRNLNNSMFGYRVFRANDYFPVNWLRVRNSLHSMKKTEDRFSPSRI
                     RQIKKGLKNGAKVEEAHTVEEIHDFSRMLHKVYSSRIRRYFPANDFFRHMNNMLIKGQQ
                     AKIFVVKYKEKIIGGSVCIYSGDDAYLWFSGGMRKTYALQYPGVLAVWKALEDAHQRGF
                     RHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRINWSWLNKLLVKFYV"
     CDS             10001..10405
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_22"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.7e-23, bitscore:
                     75.1, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAEGKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             10434..11987
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_23"
                     /sec_met_domain="CT_Btheta (E-value: 1.1e-289, bitscore:
                     952.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERLAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYVFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAKTEEEGFELIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPT
                     KPYDMYEVIGAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             12019..12939
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_24"
                     /sec_met_domain="OAD_gamma (E-value: 3.6e-15, bitscore:
                     48.5, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLVLNEILIDNQSNFQD
                     DYGLHSAWIEIFNKSFGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGKKLLDQIVVPAGALGPNQSYARVSDGAAEW
                     EVKSGSGDKYVTPSTNNKTLDSNSKMEKFEEHDADGVGMSISAMSVVFCGLILLFIAFK
                     IVGKVAVNLSKRNAMKSKGIDKHEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRETPPRK"
     CDS             12964..13395
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.7; E-value:
                     2e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_25"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.1e-21, bitscore:
                     67.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKPV
                     AKPVTVRPMPNAPAAPTQVVKPTAPSTGKSGVKSPLPGVILDIKVNVGDTVKKGQTIII
                     LEAMKMENNINADKDGKITAINVNKGDSVLEGNDLVIIE"
     CDS             13397..14557
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_26"
                     /sec_met_domain="OAD_beta (E-value: 3.7e-153, bitscore:
                     501.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATVGHVVMILVGLVFIYLAIAK
                     EFEPMLLIPIGFGILIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKNERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFVIATASGVIFVKIFNIFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDSTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             14852..16192
                     /locus_tag="ctg52_27"
                     /transl_table=11
                     /translation="MKRIIILFFLCCTIPLIAQHTDPIQEAMANYDYETALSLIAQKKT
                     TPPLLLQKGKALRGLGLTTEALATYQEIICNDTTNTRAFIEAAECCRALAKYNQALKYY
                     EHALDLNPENKYVRIQYISLLLSQQKFSEALGESSLMTEKDSSAIVLHLQAQSFEGMGE
                     LLPAAGCYYNIQAKYPDDYLAASKLGALNISGSYFDEAIEATEKYRQIDSTNISVNRQN
                     ALAYCLKQDYPTAIQRYEYLVSQGDSSFHTCYYLGISYYAAEKYYEAHDFLEVARKYDP
                     NNINLLYYLGRACSKTSWKKEGVDYLEKAIDLSIPKDSSMTRLYIGMTDCYKMAQMYKE
                     QIASIKERYQRYDKQNHKLLYDMAYIYFYDLKDKKNAERYLEAFLKTRPKDTKEEAEMN
                     ERGELVLGKSNYYNAAANWLKDIQSKQKIEDFFQNSSPQLPLPKKDK"
     CDS             complement(16277..17281)
                     /locus_tag="ctg52_28"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFEVLDAV
                     MEKLPGFPIVLHGSSSVPEEEVETINKYGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAVRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKILNVLGSDNKLAQ"
     CDS             17579..17752
                     /locus_tag="ctg52_29"
                     /transl_table=11
                     /translation="MMMTYLFYKTDYLYRSFFHKTFFYFTEKHYLCALKMTITLFLTKI
                     VTEYKLKKQILK"
     CDS             17749..18003
                     /locus_tag="ctg52_30"
                     /transl_table=11
                     /translation="MKKGLHPESYRPVVFKDMSNGDMFLSRSTVATKETIEFEGETYPL
                     LKIEISNTSHPFYTGKSTLVDTAGRVDKFMSRYGDRKKK"
     CDS             complement(18084..19298)
                     /locus_tag="ctg52_31"
                     /transl_table=11
                     /translation="MINREQYMEQIVPFIDKPFVKVITGIRRSGKSVVLRLIRDELLRR
                     GVREERIIDLNFESFQWIDLKEAKALYAYIRGQAGDAGKYYILLDEIQEVDGWEKVVNS
                     LLVDLDTDIYVTGSNSRMLSSELATYLTGRYVAFHVMTLSFREYLTFHDLQANDPTLNR
                     KEEFQKYLRMGGFPAIHTADYGYEAIYKIVYDIYSSVILRDTVQRHNIRNVELLERVVK
                     FVFDNIGNKLNAKNIADYFKSQQRKVDMNTIYNYLNALESAFIIQRIPRYDIKGKEILQ
                     TNEKYFVSDLSLIYSVMGYRDRLIAGMLENLVCLELKRRGYEVYVGKQDDKEVDFVAIR
                     REEKIYVQVTYQLASQATVEREFAPLLAINDHYPKYVVSMDSLWQDNVEGVRHRHIADF
                     LLDDA"
     CDS             19493..19900
                     /locus_tag="ctg52_32"
                     /transl_table=11
                     /translation="MEITDLKQMTKEEVFNFIRQRLSFSKELQEQFRHVNKDDLAKEHR
                     RFEMSGNESKTGQCTIFNTAILNEFADLGIYDYTSYLFLDFHNGTPTVYLKYFSENENL
                     EYTFTGYTTTEIIFAILELTIFSGKPKRNRS"
     CDS             20634..21065
                     /locus_tag="ctg52_33"
                     /transl_table=11
                     /translation="MPKWISVEKAVIKYHIEKEAILLWVEMGQFPMLYIDNVPNVDEEC
                     ILELFRRSKAGITAEYIDTLEQLCIDKTMVCEKYAHIIQLKEKEIQLQKEINTLINEIQ
                     AAMKRQNERIRDLKKAIGENNNVIRSDSWIKRLRKRFQW"
     CDS             complement(21328..21744)
                     /locus_tag="ctg52_34"
                     /transl_table=11
                     /translation="MKLIFFHRRAEYNPCHSTRKPFSTMHVIVWEKPVGGVFVVGAAEI
                     VFIFCQCPCNGKAGSVCSLQAEIGVVPSHPVYQFFYLVCTAHRFSQCQQCAVILFRILA
                     DNSCPTGNRQATVILHRFFHTDFFVLKCSHFSSC"
     CDS             22077..23381
                     /locus_tag="ctg52_35"
                     /transl_table=11
                     /translation="MTTSNSANTKQSNNASQKRKPIHNGYFNHPTSSSSNIPMSILIRE
                     QGLEIYGLYWVMLEEAHAQLKCCVNIQTMGIIANIFHAQPEHLELLYHHYFRRPGKGYN
                     SHILYADFCEESAIRSYFPHPLLAYTDNELLRMIMQDGLKAYGLYWLVMEKLYQQPQHF
                     LAPQTASFIQNLYDVSDELMESVLYNYGLFYLDEKMNLHSKAIDDYREALDNMEDEKKR
                     NTKPHVNNSLKANGNAEDFNTREMKKTSNIQKNPSPIINKEINKKNSSSEESGKEKEEE
                     NGLKVTDLNAVTPDMRPNAWEENLQEAMNDTSWYEVVAIQSGIPRLMMEEKEWFFNYLR
                     EQIILRGNESSMNSLHEIKNYFANLTRQGSHVSSTTQVALKKFLKNRQEQQQCSPYETI
                     TNGIRTYDGHPIPAYAKPRPSAAHIWNPVTNEWTR"
ORIGIN
        1 tccacagacc atgagctttc agtacttgct ccactacatc acgtccgcaa ccacgtccgc
       61 cgtctgcata agagatatac tttgctacgg atttcacttc cggcacggca tctttcggac
      121 aacatggaag tccacattca cgcatcactt caatatccgg aacatcatcg cccatataga
      181 gaatttcatc atcggtcagt ccgtatttat cacgaaaatc acgatagtcg tgtatcttga
      241 cggcggatcc catatacaga tccttcactc ccagtccttc aaaacggata cgcactgctt
      301 ctgtacggcc accggtgatg atggctatgt gaagtccttt tttcacagcc aactggatag
      361 cgtacccatc tttgatattc acagtacgca tcggctctcc ggaaggatgc aaaggtacgg
      421 ttgtcgaact caatactccg tctacgtcaa aagctaaagc cttgatacgg gataaatcat
      481 agttgatggt gctcatggat acttttgctc attagtttat atatttcctg caatgccgga
      541 gaatctacca acatggcaag atgattgttc atcacattct catcgtaacg gacagcgggt
      601 ccggtctgtg catcacgcgg tgccagttcg tgtactttac gtgccgtttc atctatcagc
      661 ggaagcatga catcgaaagg caagttgtat ttttcaagca aatcagcagc taatgcatac
      721 atgtgatttg tgaaattgca gataaaaaca gcagccaaat gaaggctttt acgctgctcg
      781 gaagaagctt cgtaaacttt ctccgaaaga gtggcggcaa cagctttcaa gagttctaca
      841 tcttccggtc ttttcgcttc aacaaagaaa ggcacttcct gaaaattgac ttcacgttgt
      901 ttgctgaatg tctgcatcgg ataaaatact ccataccgtt ctgcataccc ttcccaaata
      961 ctcatcggga tacttcccgc ggtatgcacc aacaaagaat tttgttttcc ttctgttatc
     1021 tgcggcaaca aatctactaa agcggcatcc ttcaaagata cgatatacaa tttagcatct
     1081 ttggagattt cctgtaaatc tgttgtatat tcagcttcaa ctttctcggc taaagtacga
     1141 gcagattcca tggtccggct atatacctgc acaatacgga agcctttatg atagagagcc
     1201 ttcgccagat tagtagccag gttacctgcg ccgataaaca caatcggtgt atcttctata
     1261 cttctcttca ttatttcctt accgttttgc aaaccagaat aaaatgatgc cgacaatgag
     1321 caaagtcaat ggcagcagat acccggataa cgaacccagc aatgatatta ccagactgat
     1381 attcatcacc agccaaagac caagtaacac aaaaccaatt gatttatcgc gtttgaaaat
     1441 aagaaaacag atcgaagcat acaataacat attgtcttta ttcatcaccc aaggtagtcc
     1501 aatagtggag aaatgaatca gtttatcaat cagataaagt gctccgataa cgataaaggt
     1561 aacagcagta gccaaataag tatctttgct gttactcgct ttagcagctc ccatatttat
     1621 tttcctccga atttatttat gtgaattttc tcccattgaa gatgttcttc gttgaaaggt
     1681 ttacgttcca tccctttatg tccgatagca ataacggaaa gaatttgaag ttgcagagga
     1741 atacccaaga ttccatgaac aaattcatcg gaaggcattc cggtagcagt gaaacgttcg
     1801 cggacctgca cccagcagct tcccaagccg agatcttcgg cctgcaactg tatcatgata
     1861 gaagcaatag aagcatcttc aatccaaaca tcactggcca acggatcggc cattaccaca
     1921 attgccaaag cagcgtcggc aataaatgaa gaagcctgtt ccttacaatg agacaattct
     1981 ttcaatacct ctttatcatc aatcactaca aactgccaac tattactacg tttggaagaa
     2041 ggagacatca aagctgcttt catcaatgta actacctgat cttgtgtcaa ctcttcatcg
     2101 gtgaacttcc gcatactacg acggttcttt attaattcac tgaaattttc catattattt
     2161 tccggtttca tttgattaat gtatgcaaag ataatgcaaa ccgagcgtaa taggaaataa
     2221 aagtatcttt ttcatttcta ttgtcagaag ggaatctata agatgaaaag agtgccaaat
     2281 actccactaa atgaagaata tattgtatct ttgcacagat aaataatttc attatgaaaa
     2341 agcgaattac acaagacgat tacattaaag cgaatcgtaa agctagccgt gaggcagaaa
     2401 ttgagatgta cggacaccct atttgtcaca aacgagtgca ccagtcaaag aaagtatata
     2461 accgcagaaa gataaaggca gccgataaaa agctgcctta tttttttgtc ttcaaaatag
     2521 cgtcactatc ctccagacat agcgacacta tacaatagga atggcgtcac tatcatgata
     2581 ggatagcgtc actatattta ggggattaaa aagaagttta tctatttacc taatctatct
     2641 aattatctat acaatccgag ttaattcccc ggtcgtagaa tcaataataa acccgtagac
     2701 tgtcacatct gaagggatca aaggatgacg cacgataaaa tccaccgttc ctctcaccga
     2761 cttttccgta tcttcgaagc catccagcca cgaatgaaag tcaactccgc agaaacgcat
     2821 catgtcaata taatccggat tgatcccgcg tgctttcatt ttttcgagca ttacttcact
     2881 gtgcatgtgg caagctccac agtcagaatg agcaatcacc attatttcct ctacccccaa
     2941 ttcaaaaata gctacaagta aactacgtat cacgctaccg aaaggatggg aaataacgcc
     3001 acctgcattt tttatcattt ttacatcgcc attcttaatt cctaatgcgg ctggaagcaa
     3061 agctgtcagt cgggtgtcca tacaggaaag aatagctatt ttcttatcgg gatatttatt
     3121 ggtaatatac gattcgtatc ccttgttctc aacaaattgc ttgttgtaag ctaaaatttc
     3181 ttctatcata gttccgctta aattataaag ctctgtttga tgatacaaag atatagaaaa
     3241 aagggacata tcatcacgac atatcccctc tttaatctaa atttaatctg taagagtact
     3301 aatacccatt gtttccatat tcttctgcat tatcaatctg actcaagaag ttaaaagaaa
     3361 tcggacgcaa ataatgcttg ttttcatcaa aattttcagc tgcacgagga ttaccaacag
     3421 caagacgttg tttaaaagaa tctttgtgac gcttcatcaa tacccaacgt tgatattctc
     3481 cacataattc acgagcatat tcgtccataa catcattctg tgtagcatta ctcaatttca
     3541 tagcattgta agatgcatca ttgcgagcgg cacgcttttt cagtacattt aaatattcag
     3601 cagcttttcc gccatttcct aattgttggt tagcttcagc tgcaatcaga tatacttcag
     3661 ccatacgcat aatgaacaca tcacctgtct tacgttgcaa attgctacta tatgaatctt
     3721 ccgacaacca attgtatttg ttgaaaccag ggtacatatt tttgtcatta gtaactttta
     3781 tatctgtttt acgatattgt ccgttatcaa acaaatcatc aatattgatt acataatatc
     3841 tacgtttcgc tttctccgca tccgaaagtc tttcctttga taagtagaaa cagattctat
     3901 catcatcttc agctacaggg taaggtatca cataggggtt cttcacttcc tgcaatttgg
     3961 aaggatcacc gctattttca cctttcggcc aaaccttggc tatcattttg ggcgcccaag
     4021 ttccatcata atatgtataa ttcaaatcac cataaggata aatatactca ttatggaatt
     4081 ttgcatccaa tccataagta tcgattatat tttgagtaag aattgtaaat gaactaatat
     4141 tatcatttac gccatgtttt gttccaattt ttggttttgt accatcatcc aatgtctgct
     4201 tcttattagt aaataaataa ctacctcctg actgtacggc agaaaactgt acaaaagccg
     4261 tagtaaaggt tacttcccac cgcttatcat aatcagcatc aaaacaatcc agcaaatatt
     4321 tggaaggtgc caacgtatta ttattagtac gtccatacca ataattttga ttatccggag
     4381 taggataaat agtgagagta tttggctttg gatacatata agtaaagttg ttattacatt
     4441 gtgttccagc attccagttc tccaaattcg tagcatccgg accggcagca ataaataaag
     4501 cttctttatt atttcgatta tttgccggag cccaaacatc ttccacatca tcatacagac
     4561 agtcaccata cgctaaaatc atgtcctctg ccacttcttt agcacgttgc caataagata
     4621 ctccctcttc tgtcagccca tattcgccac caccttgagc ataaacgcga gccaaaagtc
     4681 ctaacgcggt tttcttagtc acacgcgcac gattattatc ataaggagta tcttcaagat
     4741 tattggccgc aaatttcaaa tcatcaatta tctgcgtata tagttcttca atagagttac
     4801 gctgcggagt caaaatagga tcttgagacg attcttccaa tgttaacgtt acattcccat
     4861 acgtattcac caatatggaa taataaaacg cacgaagaca gcgggcttca gccactaacg
     4921 tcgttatatc tttttcattg ccatccgtta gtaattcagc cctgtttact actgcattac
     4981 aattaccgat catagaataa gcctgaccga ataatttatt tgtagcattc gtattcgtag
     5041 ctaaaccatc ataataaatc acctgcttgg cataatccgg attaccggca ggagttatcc
     5101 agcagtccgt accaccttca gccacagaca agaaatcata gacactgaat aactgcccgt
     5161 aaagtgatga ataacaataa gactgtaatc ctttaagccc atcgaacgtt gcaagaattt
     5221 catctcctgt tttttggctt ggattatact catcaagcga gcaggcagac attgaagcca
     5281 cagcgaatgt aagcgctgct attttataga ttgtactttt catttcaata ctttttttag
     5341 tgaaaaacta gaatgtaaca tttacaccaa atacaaattg tttggtcaat gggtacttca
     5401 gagaaccatt catttcggga tcatagtctt tcagcaaatg gcttttcgca aatacaaacg
     5461 gatttgtaat ggtagcatag aaacgacact tctctatacc ggctgatttt aagatagatt
     5521 tcggcagact atatcccaat gtaatgttct taatctttat aaacgaaccg tctacatagc
     5581 gtaatgcgta atatcccgta tattgttcga gacctttatt agcattggcg gcaggaaaat
     5641 catttgaagg gttgttttca gtccaataat taaaataggt cgggaagtta cgtataccct
     5701 tcgggtcata agacgtcaac atatcataag caaacatctg tccgtaacgt gcataaacaa
     5761 acacacttaa atcaaaatcc ttccaggtaa aattattctg gaatcctaaa gaccaatccg
     5821 gagagttgtg acccagaatt tgataatctg catcacttgg agtatattta ttatcagaag
     5881 tgtaataaat aacattacca ttttcatcta cagcagcact acccgtttct tcatctattt
     5941 tatagaatct accatcagat tcttttacta aattaggtat attgattttc aaatcaccag
     6001 gtgcagcacc aaataccgcc gcatcagttt cctcaccttt ttgccataca ccatccaact
     6061 tataatgata ataagagtta atagcttctc ccaatgccaa tgcataaccg gtgtcaccat
     6121 tattaagcac atctgaatct ccaccggaca atttggttat tttctcttta ttatgattga
     6181 aagttacact tgaactccag ataaagttct ttgttataat attacgtgta ttaagagcca
     6241 actcaaaacc tttattgcta gtctcacaca tatttaaatt agtagtataa ttcgctttag
     6301 gtccgccatc cggggagaat gctccattaa taacaggaag tgccttgttc catataacat
     6361 cttttgtttt tgtattataa tattccatac tgacatcaat gcgattattt aagaatgcag
     6421 cgtcaatacc aatattcgtg ttatacgact tttcccatgt aagcaaatag ttcggaatat
     6481 tctgtgagaa tttataaatc ggcgtcagaa cacctcctaa tatcatattt acagcagtag
     6541 catccaatga tgcagcagac gaatacggat caatacccgc tgtactaccc gtaacaccat
     6601 atccgaagcg aattttcaga ttactcaacc agttagtcgt actctccata aatttttcat
     6661 cagagattct ccatcccaaa gaaaaagccg ggaaagtatc ccatttatta ccttctgcca
     6721 gtctggaaga gccgtcatgg cggacagatg cagcaaataa atacctaccc atatatgaat
     6781 agttcaaacg gccgacatat cccatcccct tagacatact ataagaagta cttcccgaag
     6841 ttgcggaatt accatcaaga atattatgcc ataagaattt attatcagaa acaccttttt
     6901 gatacaaagt agtgacatcg ctacgattgt gattccaaga tgtaactgca gtaagagtta
     6961 tatcatgcac tttcttaatc tggaaattgt aagtaagtat attttcccac ttataattat
     7021 acgaacggtt gtccttaact tgcgccttaa tgccgtctgc cgtttgattt gccttatacc
     7081 attgaacaga cccctctcct gtgaaagtgt tactacgtga atatcccaaa ctagcaccag
     7141 cacgagtaat aaaagtcagc cctttaagag gagtgatttc caagtaagga ttaaaataga
     7201 ccttaaggtt ttgagcctga ttgcggtaca aacttttatc ctcatttaaa agataattat
     7261 atactgtaga tgaaggatcg gcaacaggtt gcggattgat gcttccatct tcattataca
     7321 acgatccaag aggatttgac gccatcaaag tctgtaaatc agaatcagct ttattttgat
     7381 gtacataaga cagttgagca tcaatgccca ccttcatcca ctttttaatc ttatgatcta
     7441 cccggatttt agatgaataa agtttatagc tatcttgtgc aaactgccca tcctcattag
     7501 agaagttcag agaaaaatat gcctttgtct tttccgttcc accagccaca gaaacagaat
     7561 aattctgtgt tacactggtt ttcaacaaag catccaccca atctatatat tggccatttt
     7621 gatgtgcact ccattcagca tcagtagtaa acagattttt atcatcagca accgaactcc
     7681 aacgtccatc gccagcacca acagatgcat ctctcaaggt ttgtatataa ctttctccac
     7741 tacgcatctc cggagtcctt gaccagccgt ttacacctac gtatgcatta aaattaacaa
     7801 ttgctttgcc ttccttacca cctttagtag taattaaaat aacaccgttc gcaccacttg
     7861 aaccataaat agctgtcgaa gaagcatctt ttaaaacttc aatgctttca atatcattcg
     7921 gattcaatgt agaataatcc cccggcatac catcaattat aaataaagga tttccggaat
     7981 ccttctggaa tgaccggtta ccacgcaact gcatctttac tcccgaaccg gcctgtcccg
     8041 attcacgcgt aatatccaat cctgccacct taccttgtaa agcctgcatc ggatttgaac
     8101 ttggattcat cactacatct tcacttttta cagaagtgat agctcctgtc aaatcgcgtt
     8161 ttttcatcgt accgtaaccc acaacaacca cttcatccaa tgcctgtgtg tccgaaacca
     8221 ttttcacatt gaccggtccg ttgcctgtca ctgtcaccgt ttgttctttg taaccgatat
     8281 aagaaatgac cagttctttt cttcccgccg gaagatcgat agagaagtta ccgttaaaat
     8341 cggtaatcgt acctgtactt gttcctttca caacgataga aactccaatc agcggctccc
     8401 cgctttcatc aatgatagtt cctttcacag ttttcgtttg tgtgacaact tgcaccatag
     8461 tattagaaac tccatcttct gcatacacag aatatgacag aggggcagac aataaagaca
     8521 gccctaaaat catggaagcg cgtctatgat gattcttcca tgcttcaaca aatgcattac
     8581 atctcattcg ttctaattta aagttaatat taattctcgt tgttttgcaa aaactattcg
     8641 attataatct taattaaaga cgaatctaat tttaatacgt actcactttt cataccatat
     8701 ttctcctata aaatatattt tctccattaa atacgcaact atatattata ctttacttca
     8761 agcagctcca acaaattctt tgttttgttg ttgaataaag aataaaaagt gtaaatttgt
     8821 acctagatgc cacttaaact aaccacatat tatcatggga aggacattcc tgaattacca
     8881 ggaaaaaacg ccttccattc caaagagtta tttcagattt atgaagcgac tccgggctat
     8941 actcctttat taatagtggc aacagaagac ggcagaccta tggcacgcct gcttgccgcc
     9001 atccgcaaag cgaaaaagtg gcttccctcc tctttagtga aacattgcgt agtatatagc
     9061 gaaggtgaat ttctggatga gtcgctttcg accaacaaag aaaaggcaga agaagtcttt
     9121 ggcgatatgc tcgaacatct cacacaagaa gcatcgcgta gctgtgtcct gatcgaattc
     9181 cggaacctca ataattcgat gttcggttac cgggttttcc gtgccaatga ttatttccct
     9241 gtcaactggc tgcgggtacg caattcgctg cacagtatga aaaagacgga agaccggttc
     9301 agcccgtcgc gcatccgtca gataaaaaaa ggactcaaga atggagccaa agtagaggag
     9361 gcacataccg tggaagaaat acacgatttc tcacggatgc tgcacaaggt ttattcctcc
     9421 cgcatacgca gatatttccc tgccaacgac tttttccgcc acatgaacaa tatgttaatc
     9481 aaaggacaac aggcaaaaat attcgttgtg aaatacaaag agaaaatcat tggcggttct
     9541 gtctgtatct attcgggaga cgacgcatac ctttggtttt ccggaggaat gagaaagaca
     9601 tacgcacttc aatatccggg tgtgctagcc gtttggaaag cattggaaga cgcacaccaa
     9661 cggggattcc gccacatgga atttatggat gtaggacttc cgttccgtaa acacggttat
     9721 cgtgatttcg ttcttcgctt cggaggaaaa caaagcagta cccgccgttg gttccgcatc
     9781 aattggagtt ggctgaacaa actcttagtc aagttttatg tctaaatgta atctcaagat
     9841 tacaaaacaa tgttttatgc tcctttccca ccattttttc tgtttaataa tccaataatt
     9901 aaatgcagaa atatttcttt attagataag aaatgtcttt ctttgtgctg ttttatgcct
     9961 tataagcaca gatttaaaac caaataaaaa aagtatagtt atgaagattt cacacattga
    10021 acatctgggc attgctgtaa aaagcatcga agaagccctt ccttactacg aaaatgtatt
    10081 aggtctgaag tgttacaaca ttgaaacagt ggaagatcag aaagtaagaa ctgctttttt
    10141 aaaagtgggc gaaacaaaaa ttgaactgtt ggagcctact tgcccggaga gtactattgc
    10201 caaattcatt gaaaacaaag gtgcaggcgt tcaccacgtc gcatttgctg tagaagatgg
    10261 cgtagccaat gcgctggcag aggcagaagg caaagaaatc cgccttatcg acaaagctcc
    10321 ccgcaaaggt gctgaaggtt tgaatatcgc tttccttcac ccgaaatcaa ctttgggtgt
    10381 gttaacagaa ctctgcgaac attaatcata aactctaaaa ccaacaagaa ctcatgagta
    10441 atcaacttga aaaaattaaa gagcttattg aacgccgtgc cgtagcacgt atcggaggcg
    10501 gtgaaaaagc aattgcgaag caacacgaaa aagggaaata cacagcacgc gagcgtctgg
    10561 ctatgctgct tgacgagggt agcttcgaag aaatggacat gttcgttgag cacagatgca
    10621 cgaacttcgg catggagaaa aaacattacc cgggagacgg tgtagtaacc ggctgcggta
    10681 cgatcgaagg acgtctggta tatgtgttcg cacaagactt cactgtttct gccggttcac
    10741 tgtcagaaac gatgtcattg aaaatttgta aaatcatgga tcaagccatg aagatgggcg
    10801 ctccctgtat cggtatcaac gactcgggtg gtgcacgtat tcaggaaggt atcaacgctt
    10861 tggcaggtta tgcagaaatc ttccaacgca atatccttgc ttccggtgtt atcccacaga
    10921 tttcaggtat cttcggtcct tgtgccggcg gtgctgttta ttctccggct ctgaccgact
    10981 tcacgctaat gatggaaggt acttcttata tgttccttac cggaccaaaa gttgtgaaga
    11041 ccgtaacagg tgaagacgtt agccaggaaa acctcggtgg cgcaagcgtt cactccacta
    11101 aatcaggtgt gactcatttc accgctaaaa cagaagaaga aggtttcgag ctgattcgta
    11161 aactgttgag ttatattcct caaaacaacc tcgaagaagc tccttatgta gattgcacag
    11221 acccaatcga ccgtctggaa gattctttga acgatattat ccccgacagc cctactaaac
    11281 cgtatgacat gtacgaagtg atcggcgcta ttgtggacaa cggtgaattc cttgaaatcc
    11341 agaaagatta tgcaaagaat atcatcatcg gtttcgcccg tttcaacgga caatcggtag
    11401 gtatcgttgc taatcagcct aagtatctgg ctggtgtgct cgatagcaac gcatctcgta
    11461 agggtgcacg tttcgttcgt ttctgcgatg cattcaatat tcctatcgta tcgttggtag
    11521 acgtaccggg attccttccg ggaacaggtc aggaatacaa tggcgttatc cttcatggtg
    11581 ctaaactgtt gtatgcttac ggtgaagcta ctgtgcctaa ggttacgatt acattgcgta
    11641 aatcctacgg tggttctcac atcgtaatga gctgtaagca acttcgcggt gacatgaact
    11701 acgcatggcc gactgctgaa atcgcagtaa tgggtggagc aggagcagta gaagtattgt
    11761 acgcacgcga agccaaagat caggaaaacc ctgctcaatt ccttgcagag aaagaagcag
    11821 aatacacgaa attgttcgcc aatccttaca atgcagctaa atatggctac atcgacgatg
    11881 tgattgaacc gcgcaacaca cgtttccgtg tgatccgtgc tttgcagcag ttgcagacta
    11941 agaaattgag caatccggct aagaagcatg gtaatattcc gttgtaatcc tacttttcac
    12001 attaaaacaa gaacgattat gaacaaaacc aaaatcggaa tattcctttc tttgctgttg
    12061 ctgattggtc tgacttcttg tggagagcaa aagtcgaaca ataagctggt gctaaacgaa
    12121 atcctgatag acaatcagag taattttcag gacgattacg gattgcacag cgcatggatt
    12181 gaaatattca ataaatcatt cggtagcgcc gacctggcag cttgcttgct gaaagtaagc
    12241 agccaaccgg gcgatacagt tacttatttt atcccgaaag gtgatatact aaccttagtg
    12301 aaaccacgcc aacatgcact attctgggca gatggcgaac ctaaccgtgg tactttccat
    12361 accagcttca agctgaatcc ggaaacagct aactgggtgg gtctgttcga ctccggcaaa
    12421 aagttgctcg accagattgt agtgcccgca ggcgcgctcg gtcccaacca atcatacgct
    12481 cgtgtaagcg acggggcagc tgaatgggaa gtaaaaagtg gaagcggtga taaatacgtg
    12541 actccgagca ccaacaacaa gactcttgac agcaattcca agatggaaaa gtttgaagaa
    12601 cacgatgctg atggcgttgg aatgtccatt tctgccatga gcgtagtatt ctgcggattg
    12661 attcttctct ttattgcttt taagattgta ggaaaagtag ctgttaattt gagcaagcgc
    12721 aacgctatga aatctaaagg cattgacaag catgaagcta aggaactgtc acaggctccg
    12781 ggcgaagtat acgctgctat ttctatggca ttacacgaaa tgcaggatga ggtgcacgac
    12841 gtagaagaaa cggtgctgac catcacccgc gtaaaacgca gctactcacc atggagttcg
    12901 aagatttaca ctttgcgtga aactcctccc agaaagtaag tcacctttta aaaagtaaaa
    12961 acgatgaaag aatataaata taaaatcaac ggtaactcat ataaagtaac catcggagat
    13021 attgaagaca acatcgctca tgtagaagtg aacggtacac actataaagt agaaatggag
    13081 aaacagccga agcctgttgc gaaacccgtg acagtacgcc cgatgcctaa tgctcctgct
    13141 gctcctactc aagtagtgaa accgaccgct ccgtctaccg gaaaatcagg agtaaaatct
    13201 ccgttgccgg gtgtgatcct cgacatcaaa gtgaatgtag gcgatactgt aaagaaagga
    13261 cagaccatta tcatattgga agccatgaag atggaaaaca atatcaatgc ggataaggac
    13321 ggtaagatta ctgccatcaa cgtcaacaag ggagactctg ttcttgaagg taatgacctc
    13381 gtaattattg aataatatgg gagattttat aaacttttta ggaaataacc tggccgactt
    13441 ctggacatac acaggctttg ccaatgctac ggtagggcat gtagtcatga ttctcgttgg
    13501 cttggtattc atctatttgg caatagccaa agagttcgaa ccaatgctgc tgattcctat
    13561 cggtttcggt atattaatcg gtaacatacc ttttaatatg gatgccgggc tgaaagtcgg
    13621 tatttatgaa gaaggttctg tattgaatat attgtatcag ggagtgacct ccggctggta
    13681 tccgccgctc atctttttgg gcatcggcgc catgacggac ttctcggcac ttatctctaa
    13741 tccaaaattg atgctgatcg gtgcagctgc acaattcggt atcttcggtg cttatatgat
    13801 cgcgctagaa atgggcttcg acccgatgca agccggtgct attggtatca ttggtggagc
    13861 agacggcccg acggccatct tcctttcttc caagctagca cctaacctga tgggagccat
    13921 tgcggtgtcc gcctactcct atatggcgtt agttccggtg atacagccgc ctatcatgcg
    13981 tctgctcacc accaagaacg aacgtgtcat ccgcatgaaa ccgccgcgtg ccgtttctca
    14041 cacggagaag gtgattttcc cgatcatcgg tttgttgctg acttgtttcc tggttccttc
    14101 cggtctgcct ttgctgggta tgctgttctt cggtaacctg ttgaaagaaa gtggtgtaac
    14161 tcgccgtttg gctaatactg ccagtggtcc gttgattgat acaatcacta tcctgttggg
    14221 tctgacagta ggtgcttcta cgcaagcttc cgaattcctg acgctcgact ctatcaagat
    14281 ctttgctctc ggtgcattgt catttgttat tgcaacggca tccggtgtca tcttcgttaa
    14341 gatcttcaat atcttcctga agaagggtaa taagatcaat ccgttgatcg gtaatgcagg
    14401 tgtttctgct gttcccgact ctgcacgtat ctcgcaagtg attggtttgg aatacgattc
    14461 gaccaactat ttgctgatgc acgctatggg tccgaacgtt gccggagtga tcggttcagc
    14521 tgttgctgcc ggtatcctgc tcggattctt gatgtaagat acaaggaggc tgtttgaaca
    14581 gttcttaaaa taaaaaataa gactatccta aaagccttga atttataaaa atcacctttg
    14641 ctacattata gtagtaaagg tgatttttca ttataaggac ttgctgtaaa aaagactgta
    14701 gctaccatgc cccatgtatt gtattgcgca ctgttgtgtt accttctctt atcattccgt
    14761 taatctatcc aaaataatct acgaataatt cgtaaatata atatttttag taacttgcag
    14821 cagataagtc aaacaactaa aataaaatat tatgaaacgg attatcattc tgttctttct
    14881 ttgttgtacc attcctctaa tagcgcaaca cacagaccct attcaagaag ctatggcaaa
    14941 ctacgattat gagacggccc tttctcttat agctcaaaaa aagactaccc ctcccctgct
    15001 attacagaaa ggcaaagcgt tgcgtggact aggactcacc acagaggcac ttgctaccta
    15061 tcaagaaatt atctgtaatg atactacaaa tactcgtgct ttcattgaag cggccgaatg
    15121 ttgccgagca ctagctaaat acaatcaagc actaaaatat tatgaacatg cactcgatct
    15181 gaatccggaa aacaaatatg tacgtattca atatatcagt ttgcttctct cccaacagaa
    15241 gtttagcgag gcgcttggtg aaagtagtct gatgacagaa aaagacagtt ccgccattgt
    15301 cctgcatcta caagctcaaa gctttgaagg aatgggcgaa cttcttcccg ctgcaggttg
    15361 ctattacaat atccaggcta aatatcccga cgattatctg gctgccagca aactaggcgc
    15421 tctaaatata tccggttctt atttcgacga agccatcgaa gctacagaaa aataccggca
    15481 aattgacagt accaacattt ccgtcaaccg gcagaacgct ttagcatact gcttgaaaca
    15541 agactacccc actgccatcc aacgttatga atatcttgtc agccaaggag acagttcttt
    15601 tcatacttgt tattatttag gcatcagtta ctatgcagca gagaagtact acgaagctca
    15661 tgattttttg gaagtcgccc gtaaatatga tcccaacaat atcaatctcc tttattacct
    15721 cggtcgcgcc tgttccaaaa cttcttggaa aaaagagggc gtagactatc tggaaaaagc
    15781 cattgatcta tccattccca aagacagcag tatgacccgg ctctatatcg ggatgaccga
    15841 ctgttacaag atggcacaaa tgtacaaaga acagattgca tccatcaaag aacgctacca
    15901 gcggtatgac aaacaaaacc acaaactatt gtatgacatg gcctatatat acttctatga
    15961 cttgaaagat aagaaaaatg cggaacgcta tttggaagca ttcctaaaaa cacgtcctaa
    16021 agacactaaa gaagaagcgg aaatgaacga gagaggcgaa cttgttttag gaaaatccaa
    16081 ttattataat gccgccgcca actggctgaa agatattcaa agtaaacaaa aaatagaaga
    16141 cttctttcaa aattcctctc cacaacttcc tctcccaaag aaagataaat agataagaac
    16201 tataaagcaa ctaaaaggct gctaccggtt tatcggtagc agcctttctt ttatttatgg
    16261 aataatccgg agattattac tgtgccaatt tgttgtcaga accgagcaca ttcagaattt
    16321 tgtgcttgta cagtttttcc atattgtcac gagccgggcc aagatactta cgtgggtcga
    16381 attcagccgg tttttcagcg aataccttac gtacagcagc agtcatagcc agacgagagt
    16441 cagagtcgat gttgattttg caaacagcag acttagcagc tttacgcaat tcttcttccg
    16501 gaatgccgat agcagctttc agtgcaccac catatttgtt gatagtttcc acttcttctt
    16561 ccggaactga agatgatccg tgaagaacga tagggaatcc cggaagtttt tccattacag
    16621 cgtccaatac ttcgaaagcc aatggaggag gaaccatacg gccagtcttc gggtcgatgt
    16681 ggcattgttc cggagtaaat ttgtaagcac cgtgagaagt accgattgag atagccaaag
    16741 agtcgcaacc agtgcgagta gcgaagtcga ttacttcttc agggtcagta tatgtgtgat
    16801 ggtcggaaga aacttcatct tctacaccag ccaatacgcc aagttcacct tctacagtta
    16861 cgtcaaactg gtgagcgtat tcaacaactt tcttagtcaa tgctacgttt tcttcgtaag
    16921 gaagatgaga accgtcaatc atcactgaag agaaacctga atcgatacaa gatttgcaag
    16981 tttcgaatgt atctccgtgg tcaagatgaa gaacgatttc cggatgtgcg cagcctaatt
    17041 ctttagcata ttctacagca ccctgtgcca tgtaacgcaa caaagtagcg ttagcatact
    17101 gacgagcacc tttagaaacc tgaagaatca caggagattt agtttcaaca gcagccttga
    17161 tgatagcctg catttgttcc atattgttga agttgaatgc tgggatagca tatccacctt
    17221 tgatagcctt agcaaacatt tctcttgtgt ttaccaatcc taaatctttg taatttacca
    17281 ttttgtttaa agtttattgt tagtgaataa aaattctacg caaaagtaag cattatccat
    17341 cgaataacga acatcggaaa gaaaaatata gtagaaaaag gtttaaatca gacaccattt
    17401 ttctgcagga atatgagtgt gacattagat tgtaatgtct accttgcaaa taaacggata
    17461 aaagacagta acgcgtattg cttgtatcca cgcagtcatt tatatatgaa ttaagagaaa
    17521 aatcctgtta tatgcaggat atataggtag tctgtgcctt atatagttgt ataaaccaat
    17581 gatgatgaca tacttatttt ataaaacaga ttacctttat cgaagttttt tccataaaac
    17641 ctttttctat ttcacagaaa agcattatct ttgcgctctg aaaatgacca ttacactatt
    17701 tcttaccaaa atagtaacag aatataaatt aaaaaaacag atactgaaat gaaaaaaggc
    17761 cttcatccag aatcataccg tccggtagta tttaaagata tgtcaaatgg tgacatgttt
    17821 ttgtctagat caactgtagc aactaaagaa accatcgaat tcgaaggtga aacttatccg
    17881 ttgctgaaga ttgaaatctc aaacacttct cacccgttct atacaggtaa atctacattg
    17941 gtagatactg caggtcgtgt tgacaagttc atgagccgtt acggtgaccg taagaagaaa
    18001 taattcgatc tttcgtgaaa gatgaaaaaa gaggagattc tcgcagagaa tttcctcttt
    18061 ttcgttttct atattcctta acgtcaagca tcatccaaca agaaatcggc tatatgacga
    18121 tgcctgacac cctccacatt atcctgccac aagctgtcca tgctaactac atatttagga
    18181 taatggtcgt taatggcgag caaaggagca aactccctct caacagtggc ctgtgaagct
    18241 aactgatacg ttacttgcac ataaatcttt tcttcccgac ggatggctac aaaatccact
    18301 tctttatcat cctgtttgcc tacatacact tcataacccc ttcttttcaa ctccagacag
    18361 accagattct ccaacatacc tgcaatcaac cggtcacgat agcccatcac ggaataaatc
    18421 aaagaaaggt cacttacaaa atacttctca ttcgtctgca gaatttcctt tcctttaata
    18481 tcataccggg gaatacgttg aatgataaaa gcactttcca atgcattcag ataattatag
    18541 atggtattca tatccacctt ccgttgctga cttttgaagt aatcagctat atttttagcg
    18601 ttcagcttat tgcctatatt atcaaaaaca aacttcacta cccgttcgag caattccaca
    18661 ttccggatat tgtgacgctg caccgtgtca cgaagaatga cagaagaata gatgtcgtag
    18721 acaattttat agatagcctc atatccataa tcggcagtat gtatggccgg aaatcctccc
    18781 atacggagat atttctgaaa ttcctccttc cggttgagcg tcggatcatt ggcctgcaag
    18841 tcatggaaag tcagatattc tctaaaagac aaggtcatga catggaaagc gacataccgt
    18901 cccgttaaat aagttgccag ttcggacgat aacatacgtg agttggagcc ggtcacataa
    18961 atatccgtat ccaaatctac cagaagtgag ttgaccactt tttcccaacc gtccacttcc
    19021 tgaatttcat ccaagagaat ataatattta cccgcatctc ccgcctgtcc ccgaatataa
    19081 gcatacaaag ccttcgcctc tttcagatct atccactgaa aactttcaaa attcagatcg
    19141 atgatacgtt cttcacgaac tcctctcctc aacagttcgt cacgaatcag acgcagcact
    19201 accgactttc cactgcgacg aatacccgtt atcactttta caaacggctt atctataaaa
    19261 ggaacgattt gttccatata ctgttcacga ttaatcatat tcaaaagttt ttagggttat
    19321 aagcacaaag atatactatt ttcggaaagt ttttagggtt ataaccctaa ataaatccat
    19381 gaattcagat tcttttaggg ttacaagccg aaaaataaat aaaagaaata tgactaaatc
    19441 cgatttatta ccaaataaag aaagtacctt tacccgacta attaataaaa aaatggaaat
    19501 aaccgattta aaacaaatga caaaggaaga agtttttaat ttcatcagac aacgcctttc
    19561 tttcagtaaa gagctgcaag aacaattcag acatgtgaat aaagacgatc tcgcaaaaga
    19621 acatcgcaga ttcgaaatgt ccggaaatga atcaaagaca ggccaatgca cgattttcaa
    19681 cacagcgatt ctgaacgagt ttgccgatct tggcatctat gattatactt cttatctttt
    19741 tctcgacttc cacaatggca ctccaaccgt ttatctcaaa tacttctccg aaaatgaaaa
    19801 tttggaatat acatttaccg gatataccac aacggaaatc atctttgcaa ttcttgaact
    19861 gactatcttc tccggaaagc ccaaaagaaa tcgcagctaa aaaaagaatt gcacggaaag
    19921 acaatgcgag gtcaaaagac ttttatggct ttcatttagg cacggattac acgaatttca
    19981 cggttccatt agactaaaac cgtgaaactc gtgtaatccg tgcctaaata atatcaatct
    20041 aatagatggt tttacttttg gctccctcct ttttatcatc acattatatt tgccacccgt
    20101 atagcatatt taccatcttt ataccatact ctctattctc ataccatatt tcctgcattt
    20161 atttcctctt ttccatccta ttccgaaaaa aaaatatatc tttgtcacac gctttctgcc
    20221 catcagcgtg atgaaacagg caaaagcgtt tttttattcc ttaatggagt aaataacgta
    20281 ttgtctctca aacttaaaaa ttagcagttt tttcacaccg agagatgata caacagatac
    20341 tccacgtaga tagtcgtata tcaacatatc gattagagat ttgttatata taaacgtttg
    20401 gcgtgggtgt ctgttgttta tcattatctg gtgaagggtg ttgctaagcc ttaagtttag
    20461 ataatggtac aacagcactc acgcttttat tgtatccggt cggtttcaac aatccttata
    20521 ccccaaccaa ttccccagcc gaccgaaatc ataaaaatcg tgggtgttcg ttgcacctct
    20581 ccggacaata cgttatttac tcctttttta taacacatta aaacaaaagc gatatgccaa
    20641 aatggattag tgtagaaaaa gcagtgatta agtatcacat cgaaaaagaa gcgatcctgc
    20701 tttgggtgga aatgggacaa ttccctatgt tatacataga caatgttccg aatgttgacg
    20761 aagaatgtat tctggaactc tttcgccgaa gtaaagccgg cattacagca gaatatattg
    20821 atacgctgga acaactgtgc atagataaaa caatggtctg cgagaaatac gcccacatta
    20881 ttcaattgaa agaaaaggaa attcagctgc agaaggaaat aaatacgttg ataaacgaaa
    20941 tacaggcagc aatgaagaga caaaatgaac ggatccggga tttgaaaaaa gcgattggag
    21001 agaataacaa cgttatacgt agtgacagtt ggataaaaag gctgcgcaaa aggtttcaat
    21061 ggtgaataat tatcagtgta ccaattacca tgtgggacat tattgcacgg ttttcaccac
    21121 agaggataaa gagggccgtc ctttgccctt tgcagcctat tcccattccc tccacagctt
    21181 tctttaaact cctccataag ctctttaaag cctatattca aacaatgaaa aatacaaaat
    21241 attttattcc atttatttaa ctaatcatcc attatataag taattttatc ctttgtaaag
    21301 tcaagtaaat tcactacatt tacaccacta acaagaactg aaatgtgagc atttcagcac
    21361 aaagaaatct gtatgaaaaa aacgatgaag aatgacagtt gcctgacggt ttcccgtcgg
    21421 gcagctatta tccgccaaga tgcggaagag aattacggca cactgttgac actgggagaa
    21481 tctatgcgcc gtgcatacca agtagaagaa ctgatagacc ggatgagatg ggacaacgcc
    21541 gatttctgcc tgcaacgaac agacggaacc tgcctttcca ttacagggac actgacagaa
    21601 tatgaacact atttcggccg cccctactac gaaaacccct ccaacaggtt tctcccatac
    21661 tatgacgtgc attgtagaaa atggcttacg tgtcgagtgg cagggattgt attcggctct
    21721 tctgtgaaaa aaaattaatt tcatggatta aataaggaaa gttgtaggac atatacgaaa
    21781 taaagtagtt actttgcaac cgcaagtaag agaaaaaatc atgtcaatgc tgcttccttg
    21841 ttttttgaca gaggcagtta tctgtttttc cagcattgct ttttcagaac ttcggaatta
    21901 aatctcccct gctccgaaaa ttccctatat tacagattac atacacgaag agaatactcc
    21961 gaatccatca tgaagaatga gtacgatatt tgctgctttc caaagaagtg gccggattct
    22021 tcgtatctgt attttcagaa aaatagaatt taaaacagaa actaatatat tttattatga
    22081 caacatctaa ttcagcaaat accaaacaat cgaacaacgc atcacaaaag agaaaaccga
    22141 ttcataacgg ttacttcaat catcccactt cttcttccag caatataccc atgagtattt
    22201 tgatacggga acaaggactg gaaatatacg gactatactg ggtgatgctc gaagaagctc
    22261 atgcacagct taaatgctgc gtcaatatcc agacaatggg aatcatcgcc aatatattcc
    22321 atgcccaacc cgaacatctt gagctcctct accaccatta tttccggcgt cctggtaaag
    22381 gatacaactc gcatatactc tatgccgact tttgcgaaga atctgccatc agaagttatt
    22441 tcccgcaccc cctactggca tacaccgaca acgaactgct gcggatgatt atgcaagacg
    22501 gactgaaagc ctacggacta tattggcttg tgatggaaaa gctctatcaa cagccacaac
    22561 attttctggc accgcaaact gcttccttca tccagaacct ttatgatgtg agcgacgaac
    22621 tgatggaaag tgtattatac aattacggac tcttttatct ggatgagaaa atgaacctcc
    22681 attctaaagc aatagacgat tatagggaag cacttgacaa catggaagat gaaaaaaagc
    22741 gcaacacgaa accgcacgtc aataactctc tgaaagccaa cggaaatgca gaggatttta
    22801 acactcggga aatgaaaaaa acgtcaaata tacagaaaaa tccatccccc attataaata
    22861 aagaaataaa caaaaaaaat tcttcttctg aagaaagcgg aaaagaaaaa gaagaagaaa
    22921 atggtttgaa ggtgacggac ttgaacgctg tgacacccga tatgcgcccc aacgcatggg
    22981 aagaaaatct acaggaggca atgaacgaca cgtcctggta tgaagtcgta gccattcagt
    23041 cgggcatccc ccggctgatg atggaagaaa aagaatggtt cttcaactat ttacgggagc
    23101 aaatcatctt acgggggaat gaaagctcga tgaacagcct gcacgaaata aaaaactatt
    23161 tcgccaatct cacccggcag ggaagccatg tgtcatccac aacgcaggtg gcactgaaga
    23221 agtttctcaa aaaccggcaa gagcaacagc aatgttcgcc ctacgaaacc atcaccaacg
    23281 gaatacgtac ctacgacggg catcccatcc ccgcttatgc caagccgcga ccttcggcgg
    23341 cacatatctg gaatccggtg acgaacgaat ggacacgata gcatattatc tctcaatcat
    23401 ttactaaata tggatagatt caaagaactg ggtattgata cccacggtcg cacaagcggc
    23461 aaaatgaaaa caaaatgtcc ctggtgtcat gcccaacgga cggataagcg tgataaatca
    23521 ctaagtgtca acctcgatac caaactgtat ttgtgccact actgcggcgc acacggttcg
    23581 gcagccatat atgccggaaa aggcagaaag ctgggtgatc cgttggtcaa atttccaacg
    23641 gcaacaggta gcaactccag ttgtccgccc actgaaaagc cgcacggcga cccagagcaa
    23701 ggggcactca cacagaagca aattgaatgg tgtcgtgacg tccgccacat tccgccggaa
    23761 gtattggtgg aagctggcgt ggctttcgcc tccatctcga tgcctatatc cggaaaggag
    23821 aaaggctggg aaaagaggga ctgtctctgc ttcaactttt tcgaaaacgg ggaattggtg
    23881 aacacaaagt tccgcgactc acaaaagcac ttcaaattgc tgcaaggagc gcgcaccatc
    23941 ccttacaaca tcgacgccat ccgcgacacg ccggagtgca tcctcgtgga aggggaattt
    24001 gatgccctct cctacatggc tgtcggccgg acggatgtca tttccgtgcc gaacggtgcc
    24061 aacagtcaac tggactggct ggacgaattg tcggaatctc atttcgagca gaaacaagtg
    24121 atttatctgt cggtggacac cgaccgcaag ggacgggaac tgtgccggga actctcccga
    24181 cggctggggg tagaccgctg ccgtatcgtc acctacggcg aagcatacaa ggacgccaac
    24241 gaactgctcg tggcggaagg cccggacgca ctactgaagg cactggagga cgcacccatc
    24301 ccccgcctgg aaggtacgtt tacggcagaa gacttacggg aggggttgca ccaactgttt
    24361 gaagaggggt atacttcggg cgtggaattg ggaataccga atctggacga aatcatgagg
    24421 ctggaaacgg ggcgagtgct caccgtcacc ggtattcccg gacatggcaa atcggacttt
    24481 gtggatgaga tagtgctccg gctctgcacc cgccaagatt ggcgagcggg atatttcagt
    24541 ccggagaaca cgccaat
//
