LOCUS       gnlProkkaKABPKLGH_286  15214 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KABPKLGH_286.
ACCESSION   gnlProkkaKABPKLGH_286
VERSION     gnlProkkaKABPKLGH_286
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 04:07:44
            Original ID  :: gnl|Prokka|KABPKLGH_286
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15214
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15214
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4863:5214]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4864..5214
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15214
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15214
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..182
                     /locus_tag="ctg286_1"
                     /transl_table=11
                     /translation="MAGKGVACGDSFRQAIYVAIDVFRNRQREKVARANPLRKQYYEKR
                     DDSDKLKLDTVDED"
     CDS             192..1433
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg286_2"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             1420..1947
                     /locus_tag="ctg286_3"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             1953..2726
                     /locus_tag="ctg286_4"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQSSEETPKLKGYELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDEPTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             2733..3128
                     /locus_tag="ctg286_5"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPAAETPAPAAE"
     CDS             3456..4766
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 85.2; E-value: 5.8e-26)"
                     /gene_kind="transport"
                     /locus_tag="ctg286_6"
                     /transl_table=11
                     /translation="MLCGYFLTDVMSPLKPMLEKELLWDSLDYGFFTSAYGWFNVFLLM
                     LIFGGIILDKMGVRFTGMGACLLMVFGCGLKYYAISTTFPEGAMLFGFKTQVTLAALGY
                     AIFGVGVEIAGITVSKIIVKWFKGKEMALAMGLEMATARIGTTLAMVLTVPLADFFGST
                     DESGTFHTNIPAPILFCLIMLCVGTIAFFLYTFYDKKLDASLDAEGLEPEEPFRMKDIV
                     YIITNKGFWLIALLCVLFYSAVFPFIKYAADLMVQKYNVDPKLAGTIPGLLPIGAIILT
                     PLFGSLYDRIGKGATLMIIGSVMLIFVHTMFALPILNIWWFATIIMIILGFAFSLVPSA
                     MWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVPLLIGWVLNTYCKGPVVDGAQTYDYTL
                     PMTIFALFGVLALIVALMLKAENKKKGYGLEEANIQK"
     CDS             4864..5214
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg286_7"
                     /sec_met_domain="PqqD_RRE (E-value: 2e-11, bitscore: 34.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 7.1e-18, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(5233..5517)
                     /locus_tag="ctg286_8"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGGLIAIAVILWAVFIK"
     CDS             complement(5554..6621)
                     /locus_tag="ctg286_9"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVSKKVAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDDK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             complement(6694..8205)
                     /locus_tag="ctg286_10"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPITSIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             8934..9158
                     /locus_tag="ctg286_11"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             9353..10897
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 46.8; E-value: 2.5e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg286_12"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASTLDNTN
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKADHISHPKMDKRTKVRNTLVITILTIALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDIFGWEMPASW
                     FQSFNPLFVVVLAYIMPGVWGFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAVP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             10938..11474
                     /locus_tag="ctg286_13"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             11534..12103
                     /locus_tag="ctg286_14"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             complement(12175..12333)
                     /locus_tag="ctg286_15"
                     /transl_table=11
                     /translation="MTSSSTIAPVGTSVRTIFLAPHVRRASSALTRATVYLYVINKIRF
                     SHIFLKS"
     CDS             12340..13356
                     /locus_tag="ctg286_16"
                     /transl_table=11
                     /translation="MRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVP
                     CGTVVYNAETGEYLCDVTEDGQEVVLLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEM
                     TVIMELKLLADVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSF
                     VMADIPGIIEGASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNP
                     EMLDKQRVLAVTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNK
                     ESNKIEDIVHRPKDVTRLQQELKDMGEDEDIVYEYEEDVDDDDDIDYEYEEEDWEEK"
     CDS             13353..14165
                     /locus_tag="ctg286_17"
                     /transl_table=11
                     /translation="MISLTKHNELKGYKSLEAYPEVAHFVTTRHEGISTGAYGSFNCSP
                     YTNDSCMNVNRNQSWLFQCMNHQIKELFIPEQSHGCASLIINESFFKESLEMRRLLLRG
                     MDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSHVMDHLNKMF
                     GTQGEDVIACIGPSISLESFEVGDEVYDAFEESGFDMSLISMKKKETGKYHIDLWEANR
                     IELLNLGVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRTLSGIMIRK"
     CDS             14216..14881
                     /locus_tag="ctg286_18"
                     /transl_table=11
                     /translation="MFEIKVSKEIKDACPVFAGAAVYAVVKNTAYSEGLWQEIDAFTKQ
                     LTSTTQMEDIKHQPVIFATREAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDL
                     INLVSLRTGHSIGGFDADKIQGTHLELGIGKAGEPFEGIGRGVLNIEGLPVYRDSFGGI
                     GTPTSDHERTKMDLETTHILAIVNGYNGKEGLQEAVEMIQTLLRNYTESDGGEIVFFE"
ORIGIN
        1 atattgcagg caagggagtg gcttgtggag attctttccg tcaggcaatc tatgttgcca
       61 tcgacgtgtt ccgtaatcgt cagcgggaaa aagtggctcg tgccaatccg ttgcgtaaac
      121 agtattacga gaaacgtgac gatagtgata aactgaagct ggatacagta gacgaagatt
      181 aaaaacgagt gatgacgaaa gcagagatac aacaagtgaa acagcgtttc ggtattattg
      241 gaaatactga agcattgtcg cgcgccatag atgttgccat tcaggtagct cctaccgatt
      301 tgtctgtgct gattaccgga gaaagtggag tcggaaaaga aagttttccg cagattattc
      361 atcaatatag tcggaggaag cacgggcagt atattgctgt caactgtggc gctattccgg
      421 agggtacgat tgattccgaa ctgttcggac atgagaaagg tgcgtttacc ggtgcgattg
      481 gcgaacggaa agggtacttt ggcgaagctg acggtggtac tatttttctt gatgaagtag
      541 gggagttgcc gatgtctacc caggcacgtt tgctccgtgt actggagagt ggcgagttta
      601 tgaaagtagg ttcgtccaaa gtacaaaaaa cggatgtgcg tgtggtggca gctaccaacg
      661 tcaatctgac acaagcgatt gcagaaggac gtttccgtga agatttatat taccggttga
      721 atacggtgcc tatccaaata ccgcctttgc gtgaacgtgg tgacgatgta cttttgttgt
      781 tccgtaagtt ttccgcagac tttgcagaga aatatcggat gcctgctatt cagttgacgg
      841 aggatgcgaa gaaagagttg ttagcttacc cgtggcccgg aaacgtgcgt cagttgaaga
      901 acatcaccga gcaaatatct atcattgaaa ccaataggga gatctctgct gctatcttgc
      961 agaattatct tcccgcacaa aatacgcaac gtcttcccgc gctgatggga acgcgtgaga
     1021 gtaaaggctt tgagagcgaa cgggagattc tttattctgt tctgttcgat atgcgccagg
     1081 aagtggcgga gctgaagaag atggtgcaca acctgatggc ggaacgtgcc ggacaggtgg
     1141 ggcaggtagg acaaatggga acggtggtta ctactccggt agtgacggcg catcaacctt
     1201 cggtacctgc tatcattcac accatgcagc ctacggtttg caaggatgac gatgacatac
     1261 aagacacgga agaatatgta gaagaatccc ctttgtcact ggacgaagtg gagaaagaaa
     1321 tgatacgcaa agcacttgag aggcatcatg gaaagcggaa gagtgcggcc aaggacttga
     1381 atatttccga gcgtacactt tatagaaaaa taaaagaata tgaattggat taagaaaata
     1441 atacgccctt tgttactgtt cggcttgccg ttggtagtca ttgcgtgcac tgtttcctat
     1501 aagtttaacg gatcgtctat caattatgat aaggtaaaga ctatttcgat agccgacttc
     1561 ccgatcaagt cggagtatgt atatgctccg ttggcaacca aattcaatga ggacctgaaa
     1621 gatatcttca tccggcagac ccgtctgcaa ctgctcaagc cgaatcagaa tgcggacttg
     1681 cagattgacg gagaaatcac aggatacaat cagtacaacc aggcagtatc tgccgacggt
     1741 tattcttcgg agacgaagtt gactattacc gtcaatgtgc gttttgtcaa caataccaat
     1801 catgccgaag actttgaaca acagttttct gcgttccgta cctacgactc tagccagttg
     1861 ctgactgccg tacaggacgg attgattgct gaaatgtcta aagagatcac cgaccaaatt
     1921 tttaatgcaa ctgtagcaaa ctggtaatat aaatgacttc tgttaacttt caacaatgga
     1981 ttcagcatcc cgagacgctg aatagggata ctttgtacga actgcgcaat cttcttgcga
     2041 ggtatccgta ttttcagtca cttcgtctgc tgtatctgaa gaatctgtat attctccatg
     2101 atattagttt tggtggagaa ctgcggaaag cagttcttta cattgcagac agacggcagt
     2161 tgtttcggtt gattgaaggt gaccgctatg atgtgcaggc acggaaaaag ggagtacctc
     2221 tcacggaggt gctgaaagac gaaccgtccg tagaccgcac attagcattg atcgacgctt
     2281 tcttgtccac agtacccgaa gaggtgactg cccgcaccag cttcgactat tcgatggatt
     2341 acacttctta tcttttggag gagactccgg ccacggaaca gtcgtccgaa gaaacgccca
     2401 aacttaaagg ctacgaactg attgacgact ttatagaaaa gagcgagagc gactctcccc
     2461 tctgcatgaa acctttaaga gaagaaatgc catcttcgcc aacctcttcg gacgaaccta
     2521 ccgaagaaga aacgatgaag gaagaagagg aagatgacag ctgttttacg gaaactttgg
     2581 caaaaatcta tgttaaacag caacgatatt caaaagctct tgaaataatt aaaaaattaa
     2641 gcttgaaata tccaaaaaaa aatgcttact ttgcagacca aatcagattt ttggagaaat
     2701 tgattattaa cgctaattca aaataactaa aaatgtactt attattcgtt atcttaatgg
     2761 ttattgcagc cttgttgatg tgtttcatcg tgctgattca gaactcaaaa ggaggcggac
     2821 ttgcttctgg tttctcttca tctaacgcca tcatgggcgt gcgcaagact acagattttc
     2881 tggaaaaagc aacatggggc ttagctatct tcatggtggt aatgagcatt gctactgctt
     2941 atgtagttcc tcgctctgct gttgctaaag acgcagtgtt ggaacaggca cagaaagaac
     3001 aacagactaa cccgtataac ttacccgcag gtacggctgc gccgcaaact gaagctcctg
     3061 ctaccaatgc acctgctaca gaaactccgg caccggctgc tgaaactcct gctcctgcag
     3121 cagagtaatt cactccgttg tcaggtaaga ctttggggga aaaccattaa tgggaaggtg
     3181 cagacggatg ctgcatttct ttgatattta agtgcggatt acgcagatta cacggatttt
     3241 caatcttccg cgtggtcagt gtaatccgca cttaactttt tcttgtaaaa acaatctctt
     3301 tttgatagaa acaaacgaga tttaactacc tttgttggtc gtatgaagat tattaactac
     3361 tatttttaaa tataacaatg acagaacatt tgaaacagaa attgaatgac tccgccgtac
     3421 tccgatggag tgttctagca ttagtcgcat ttactatgct atgcggctat ttcctcaccg
     3481 acgtaatgtc tcctctaaaa cccatgcttg agaaagaact actatgggac agtcttgatt
     3541 atggtttctt cacaagcgct tacgggtggt ttaatgtatt cctattgatg ctgattttcg
     3601 gtggtatcat tttggataag atgggagttc gtttcaccgg aatgggggct tgcttattga
     3661 tggtgtttgg ttgtggattg aaatactatg cgatttctac tacttttccg gaaggtgcca
     3721 tgctcttcgg attcaaaaca caggtaaccc tggctgcatt ggggtatgct atcttcggtg
     3781 taggtgtgga aattgccggt atcacagttt ccaagattat cgtgaaatgg ttcaagggta
     3841 aggaaatggc gttggctatg ggacttgaaa tggctacggc acgtatcgga acaactctgg
     3901 caatggtgct tacggttcct ttggccgact ttttcggatc tacggatgag agtggcacat
     3961 tccataccaa tattcctgct ccgattttgt tttgtctgat tatgttgtgc gtgggtacga
     4021 ttgctttctt cctttatact ttctatgata agaagttgga tgcttctttg gatgcagagg
     4081 gattggaacc ggaagagcca ttccgtatga aagatattgt gtatatcatt accaataaag
     4141 gattctggct gattgcatta ctatgtgtat tgttctactc ggctgtattc ccctttatca
     4201 agtatgctgc cgacttgatg gtgcagaagt ataatgtaga tccgaagttg gcgggaacga
     4261 ttcccggatt gttgccgatt ggtgcgatta tcctgactcc gttgttcggc tcgctttatg
     4321 accgtatcgg taagggagcc acattgatga taatcggatc agtgatgctt atttttgtgc
     4381 atacgatgtt tgctctgcct atactgaata tatggtggtt tgctactatc atcatgatta
     4441 tattgggatt tgccttctcg ttggtgcctt cagctatgtg gccgtctgtt ccgaagatta
     4501 ttccggaaaa acagttgggt accgcatacg cattgatttt ctgggtacag aactggggat
     4561 tgatgggtgt tcctttgttg atcggatggg tgttgaatac ttattgcaaa ggtccggtag
     4621 tagacggtgc acagacttat gactacacgt tgccgatgac tatttttgct ctttttggtg
     4681 tgcttgctct gattgtggct ttgatgttga aggcagagaa caagaagaag ggatacggtt
     4741 tggaagaggc gaatatccaa aagtaactgg gaaattcaat acctaaagta acaaaggaat
     4801 tttgtatcaa ggtgtaaaca gaagagtatc agtatgaata ctctgaaata aaaaataaga
     4861 agtatggctg ccaaagagaa aatcaacctg ttagaggtca ttccctgtcg cagtgaacat
     4921 attacagcag aaagggaagg ggagacaatt gtgctctcct ttccccgttt taaatatccg
     4981 tggatgcaac gcttccttgt gccgaaagga atgtcgaaag aacttcatgt gaaattggaa
     5041 gaacacggta cggctgtatg ggaactgata gatggaaaac gcaatgttcg tgagattata
     5101 gaaaaactcg cagaccactt tcaaaatgaa gagggctacg agtcgcgtgt atcggcttat
     5161 ctttctcaaa tgcagaaaga tggatttata aaactggtga taccagtcgt ataaatagga
     5221 acttattatt atttatttga taaatacagc ccaaagtatg acggcaattg ctatcaggcc
     5281 ccccatgata ataagcgttc cccaaacaaa ataattgctg tctttctctt tctttttctc
     5341 cgagtcgtgg atgatacgtt ccatttcttc gggggtggtg ttgggtagtg gataaggttc
     5401 gtttgcacgg tttagatgct tcaacttatc gttagcacgt tcacgacgta ggcgggaagc
     5461 ttcccgtccc tcttttattc ggcgtatcat gtcgaatgca tgtccttcac caaccatatt
     5521 ctttgttttt tagaagttca cttcctcgtt tttctatttc ccttcttctc tgtccacttt
     5581 gagcaatcct cccgtattcg gatcaaaata aactttgatg gtagaattct tgttgaacaa
     5641 aaccggagcc agatattcta tcacaccgaa ttgggtaata ggaagctcac cttcgtaaag
     5701 tttcttttta ccgtcagtca gtgtaaccat agcttgtccg ggtacgttgt aggcgattcc
     5761 atccaaatct ttcttcttct tatcgtcttc ctgtggtatc ttgaccgatt tcaggtcttt
     5821 cagactgata taaaacggag ttcctgccaa atcattgttg gcaactacac ctaacttctt
     5881 cgagaagcgg aaggcaactt cattgttgaa ttccttgtca ggggtaaggc ggacagtgaa
     5941 tgttctctct tctttgttgc aggtgccgga gaacatttgc gtcatggctt cttcctgtgc
     6001 attcagattg tcgagcataa ttttaagctg tgccccatct gaaggcatat tatcagcttg
     6061 tccgcgcaat aaggcatttt tgctttcgcg gatgttatag atttctttag ccaccagctc
     6121 ggccatcttg gcggtagaac tagccatcag aatctcttcg gtcaggaatt cgcgaggatt
     6181 cgctttcttt tggaggactg cgggggcggg agcaactttt ttgcttacac tgctgttgct
     6241 gtaaggaaca ttgatcgttt tcacaatgcc atcctctgtc agttccataa gcggtgctac
     6301 tgtcttatcc ttcaatttta cgaaatacgt agtttcgctg ttgggcacac ctacggattt
     6361 cacttttacg ctagctagtt cccaatactc ttcagggtcg gcggagacgt tggtcagtcg
     6421 caggtaacga tcagcatatt tgctgaattc tcccggagta tagttgactt tgttggcttt
     6481 tatttcaagt tctatttggg ttttgggaag actgtaaacc actccatagt cttttcctcg
     6541 ggtaaccccc gtcagtactt cggtttgtgc ataggcggac gttgtcataa gtagtcctgc
     6601 tgctataatc aactttttca tattcggttc tttttaactg gttttgaaaa caaagttaat
     6661 gaagttattg aaaaaagggt aacttcttaa cttttattcg cttacaagtc gccatgctgt
     6721 cggcagacag gtgataatat cgcttgcgat cattccgatc attccttgct tcttttgagc
     6781 gacatcgccc gccagtccgt gaatgtaagt gccgatttta gcggcttcct cggtggggta
     6841 accttgtgcg agcagcgcca ggattactcc ggtcagtacg tcaccgctac ctccggttgc
     6901 cattcccgga tttccggttg ggttgaagaa acatttacct tcgggggtga tgatggcgga
     6961 gtaggctcct tttaaaataa tgtgaacatg ggcggcacgg gccagttcgc aagccttcat
     7021 cagacgttcg taagagtcct ggcatttgcc ggtcagacgt tccagttctt tcggatgcgg
     7081 ggtgaggatg gaacccttcg gcaggtgggt aagggcatgg cggtggttgg caaggatatt
     7141 aagtgcgtcg gcatccacca caacaggagt ctggcagtgt tccagttgtt ccaacaaggc
     7201 agcttccgtt tcctcgtttc gtcccagtcc cgggccgatg ccgactgctt gatagtcgtc
     7261 cgtgtcggta ggtacggcaa aacaggtttc gttgatgtcg gtttctacga ttgcttcggg
     7321 tatggaggtt tgcaagatgt cgttgttgca cattggcgca tggacagtca gcaaccctac
     7381 tcccgaacgg aggcaggcgc gggcagcgag aacagaggct cctgccattc cttttgaacc
     7441 ggcaatcaat agtgcatgac cgaagttccc cttgtgggca aactgtttgc gtggcttgat
     7501 gagtgaccgg atttgctcta tttccaacat ttcgtagttc gtttccatct cttcaatgcc
     7561 gtcttcgctc aattggatgt ccaacaattc ccattctccg acaaattccg tgttctctgc
     7621 gaaaagaaag gcgagcttcg gcagttgcag actgaaagtt acgtcggcac ggataatatt
     7681 agcttttacg ttgaatgtat tttcttctcc catcagtccg gaaggaatgt cgatggctac
     7741 taccatggca ggggaggaat tgatgtattt cactacggca gcgaatccgc cgctcaacgg
     7801 tttgttcagg cctgaaccga ataatccgtc gattaccagg tgatcgggcg ttaggacggg
     7861 aggtacgaat tgggtactga tttcgtggaa ttttacttct tccatcattt ctaccagttc
     7921 tttattggtc tggcagtcgg gtgaaagttc tcctttcgtg ttgaagagaa atacctcgat
     7981 tttatatcct ttttcagcca tcatgcgggc tacggcgaga gcgtctccgc cattattccc
     8041 cggtccggca aagatagtga ccggcgtttc cgtattccat ctgtctgtga tggcttttgt
     8101 taatacggtt gctgcacgtt ccatcagatc gattgatgta ataggttcgt tctcaatggt
     8161 ataagcgtcc aatttcttga tactgctgct tggaaatatt ttcattgcga tgttctttta
     8221 gttttcggat tacaaatgta catgattctt ctgacttttc ccgtttgttg tgggaagaaa
     8281 acttgttaat cataaggaga tgacttgttg ggggcaggga aatgaatcaa actcgtggtg
     8341 gtttgattta ttaaaaataa tcattttgta cctttcacaa gtttcacgga cacgtaagtt
     8401 gtagtgtgac agatgtttgt tgtgatttaa ggttctcttt ttaattcttc acatctttca
     8461 cactgttcac acccttaaga aagaagcccg gtcaaagcaa aagcttaggt gtttcttcaa
     8521 tatggcaaga cataggagaa cgaatatgat tgaagaccgg attgaaatag ttggcatgat
     8581 attagccaac tgtagttggc tacttagatg actactgtcg gctacatggt caactgcagt
     8641 tgactaaata gctgacttca gttgtctatt aataactcaa cttcaaaatt gtcgtatagt
     8701 gccgacatta ggcagtatta agctatatac ctcatgtgtg gttacggttt ccttcatctc
     8761 cataccttct taaacaaatt tttaatgcgg ttcccctgat taagcctttg attatttgcc
     8821 gtttccgata aaaatgttat ctttggagat aggtaatgtg catcacatta atttcctgtg
     8881 ctcacaatga attagaatct aaataacgga ttgtttaatc ttctaaagtt tgcatgatgg
     8941 aaaagacaaa aattggcttg aatgccggga aagtatggcg catcttaaat gaaaaaggtg
     9001 aactttcaat gttcgatttg tgccgtgaat taagtttgac gtttgaagac gtagctcttg
     9061 ctattggttg gctggcccga gaagacaaga tctttttgag gaaaagagaa ggaatgcttt
     9121 ttgccagtat cgaaaatgtc gaatttactt ttggctaagg tggtagctaa cctacattta
     9181 agatggatct ccactttatt atttacactg ctaaaaaagt aatgaagtgg atcagtagga
     9241 ttttttatgc tcgtttttac tattcccccc tattattctg tttgataaga gaagcatcta
     9301 atctactttt tctgtacctt tgcaccccat aaactactaa acacataaat tcatgagtgc
     9361 attgaaaggg catccgaaag gcctttattt gattttcgcg acaagcacgg cagaacgttt
     9421 cagttattac ggtatgcgtg cgatctttat tcttttcctg acgcaggcat tattgtttga
     9481 caaagaagcg gcagcatcca tctacggcag ctataccgga ctagtttatt taaccccgtt
     9541 gattggcgga tacattgccg ataaatattg gggaatccgt cgttccgtgt tttggggagc
     9601 ggtgatgatg gcagtcggac aattcctgat gtttatgagt gcttccactt tagataatac
     9661 gaaccttgcc cactggatga tgtatggcgg actaggcttc ctgatcttgg gcaatggttg
     9721 cttcaaaccc actgtctctt ctctggtagg tcagctctac gaacccggag acaggcggtt
     9781 ggatgctgca tacaccattt tttatatggg agtgaatgta ggctcttttg ctgctccttt
     9841 gatttgtggt tatctgggtg ataccggtga tccgcatgac tttaaatggg gatttcttgc
     9901 agccggaatc atgacactgt tcaccgttgt tcttttcgag actcaaaaga ataaatatct
     9961 tttttctcct tccggagaac cgattggtat tatccccgat gctaaacgtg aaaagaaaga
    10021 agacaaggcc gaccatatct cacacccgaa gatggacaaa cgtaccaaag tacgtaatac
    10081 ccttgtaatc acaattctta ccattgcttt aatagccttc tttaactatg catttgaagg
    10141 cgattgggtg agtatcggca tttttaccgc ctgcattgtt ttccctgttc tgatcctgtt
    10201 agacggttca ttgacaaaaa tagaacgcag ccgtattttc gttatctata tagtagcctt
    10261 ctttgtcatc ttcttctggg cagcctacga acaggcggga gcttctttaa ctctctttgc
    10321 gtccgaacag acgaatcgtg acattttcgg ttgggaaatg ccggcttcat ggtttcaatc
    10381 cttcaatcca ctgtttgtag ttgtcctggc atatatcatg ccgggtgtat ggggtttcct
    10441 gaacaagcga aagatggaac ctgcttctcc taccaaacaa gcgattggtc tgttactcct
    10501 ttctttaggt tatcttttca tctgtttcgg agtgaaagat gcagttcccg gagtgaaagt
    10561 gagcatgatt tggctgacag gactttactt tattcatacc atgggtgaaa tagctttgtc
    10621 gcctatcgga ctttcaatgg taaataaatt gagtccgctg cgtttcgcct ccttgatgat
    10681 gggaatctgg tatctgtcta ctgccacagc taataaattt gcgggaatgt tgagcggact
    10741 ctatccggaa gccggaaaag tgaagtcaat ctttggttat cagattgcta ccatgtatga
    10801 tttctttatg gtattcgtcg tgatgtccgg tgttgcttcg ttgattctgt tccttctctc
    10861 gaagaaatta cagaagatga tgcacggggt agaataaaaa atcgtatttt tgcaaggtta
    10921 tttttaaatt accggttatg gataccattc agataaaaga caaattgttt accgtttcca
    10981 ttaaggaaca agaaattcag aaagaagtga ttcgcgtagc gaacgaaatt aaccgcgatt
    11041 tggcaggtaa gaatccgctt ttccttagtg tgttgaacgg ttcgttcatg tttaccgctg
    11101 atttactgaa gcacatcacc atcccttgtg aaatctcatt tgtgaagttg gcgtcttatc
    11161 agggcatcac ttccaccgga gtgattaaag aggtaatcgg cctgaatgaa gacattgccg
    11221 gacgtaccat tgtaatcgta gaagatattg tagacacagg actgacgatg cagcgactgc
    11281 tcgaaacatt aggtacacgc aatcccgaag ctatccatat cgcttctctg ttggtgaaac
    11341 ctgaaaagct caaggtaaac ctcaacattg aatatgtagc gatggaaatt ccgaacgact
    11401 ttatcgtagg ttacgggttg gattatgatg gtttcggacg taattatccc gatatttata
    11461 cagtagtaga ttaatattaa ataggtacca gtttaaatgg taaatagtaa atcgttaaat
    11521 tgtaaataac aaaatgttga acatcgtaat tttcggtgct ccgggttcag gaaaaggaac
    11581 acagagcgaa cgtatcgtag aaaagtatgg aatcaatcac atctcgacag gagatgtatt
    11641 gcgtgctgaa atcaagaatg gcacagaact gggtaaaaca gctaaaggtt acatcgacca
    11701 aggtcaattg attcctgatg aattaatgat tgatattctg gcaagcgtat tcgacagctt
    11761 caaagatagc aaaggtgtaa ttttcgacgg tttcccaaga acaattgcac aagcagaagc
    11821 attaaagaaa atgttggcag aaagaggaca ggacgtttct gtaatggttg acttggatgt
    11881 tccggaagaa gaactgatgg tacgtcttat taaacgtggc aaggattccg gtcgtgctga
    11941 tgataacgaa gagacaatca agaaacgtct gcatgtatat cattcacaga ctgctccact
    12001 gatcgactgg tacaagaacg aaaagaaata ccaacacatc aacggcttgg gtactatgga
    12061 aggtatcttc gctgaaatct gcgaagcagt agataaattg taataataca atattataaa
    12121 taaataagtc agtagccgga gtgttctaat taactgctct aactactgac tactttaact
    12181 ctttaaaaaa atatggctga atcgaatttt gttgattacg taaagatata ctgtcgctcg
    12241 ggtaagggcg gaagaggctc tacgcacatg aggcgcgaga aatattgtcc taacggaggt
    12301 cccgacgggg gcgatggtgg aagaggaggt catatcatct tgcgcggtaa ccgtaattac
    12361 tggacattgc tgcacttgaa gtatgaccgt catgcaatgg ccggtcatgg tgaatcgggg
    12421 agcaaaggac gtagcttcgg aaaagacggt gcggataaaa taatagaagt gccctgcgga
    12481 acggtagttt ataatgccga gacaggggag tatctttgtg acgtaacaga agacggacag
    12541 gaagtggtct tgctcaaagg cggccgcggc ggtcagggta actggcattt caagacggcc
    12601 acccgtcagg ctccgcgttt tgcgcagccg ggagagccga tgcaggaaat gaccgttatc
    12661 atggagctga aactgcttgc cgatgtcggt ctggtaggtt tcccgaatgc gggaaagtca
    12721 actttgcttt cttccatttc ggctgccaaa ccgaaaattg ccgattaccc gtttactacg
    12781 ctcgaaccca acttgggcat cgtttcctat cacggtggaa aatcctttgt gatggcggac
    12841 ataccaggta ttatcgaagg tgctagtcag ggaaaaggtt tgggactgcg tttcttgcgt
    12901 catatcgagc gtaattcatt actgctgttt atggttccgg cagacagcga cgacattcgt
    12961 aaagaatacg aagtcttgct gaacgaactg cgtaccttca atcctgaaat gttggacaag
    13021 caacgtgtgt tggctgtcac caaaagtgat atgctcgatc aggagttgat ggacgagatt
    13081 gaacctacat tgccggaagg cattccacat gtattcatat cttctgtttc cggtttgggt
    13141 atctcggtgt tgaaagacat cctttgggaa gaactgaaca aggaaagcaa taagatagag
    13201 gacatcgttc accgtccgaa agacgtgacc cgtctgcaac aggaactcaa agacatgggc
    13261 gaagatgaag acatcgttta tgaatatgag gaagatgtcg acgatgacga tgatatcgat
    13321 tatgaatacg aagaagaaga ttgggaagaa aaatgatttc acttacaaaa cataacgagt
    13381 tgaaggggta taagtcactg gaggcatatc ccgaagtagc tcattttgta actacgcgtc
    13441 acgaaggtat aagcaccgga gcttacggct ctttcaactg ttcgccttat accaacgact
    13501 catgtatgaa cgtcaatcgc aatcagagct ggttgtttca gtgcatgaat catcagataa
    13561 aagaattatt tattcctgaa cagagtcatg gttgtgccag tctgattatc aatgaatcat
    13621 tttttaaaga atcattggaa atgagacggc tacttctgcg aggaatggat gccttgataa
    13681 ctaatgtgcc gggatattgc gtttgtgtca cgacggcgga ttgtgttcct gtattgctgt
    13741 acgacaaaaa acaacacgtt gtggctgccg ttcatgctgg atggaaagga acggtgaagc
    13801 atattgtcag tcatgtgatg gatcacttga ataagatgtt cgggacgcaa ggtgaagatg
    13861 tgatagcttg catcgggccg agcatttcgc tcgaatcatt tgaagtaggt gatgaggtgt
    13921 atgatgcttt tgaagaaagc ggcttcgata tgtctcttat ttctatgaag aagaaggaga
    13981 caggcaaata tcatattgat ttgtgggaag ccaaccggat tgaattactg aatctcggag
    14041 tgcctgcaga acagatagaa gtggccggaa tctgtaccta tattcatcat gatgaattct
    14101 tctccgcgcg tagactggga atagattccg gtcgtacatt gtcgggaata atgattagaa
    14161 agtaataatt ggtgtccgtt attgcaggac gctgatgatt ggtttatgat aagttatgtt
    14221 tgaaataaaa gtatctaaag aaataaaaga cgcatgtccg gtttttgccg gagccgctgt
    14281 gtatgctgtt gtgaaaaata cagcttacag cgaagggctt tggcaggaaa tcgacgcttt
    14341 taccaagcaa ctgacttcca caacacagat ggaagacatc aaacatcaac ccgttatctt
    14401 tgctacccgt gaggcttata aacgttgtgg caaagacccc ggacgttacc gcccgtcagc
    14461 cgaagctcta cgccgccgcc tgatgcgtgg aattccttta tatcagattg atacgttggt
    14521 agaccttatc aaccttgtgt ctcttcgtac gggacattcg atcggtggtt ttgacgcgga
    14581 caaaatacaa ggtacgcatc ttgaactcgg tatcggcaaa gcaggagaac cgtttgaagg
    14641 tatcggacgc ggggtattga atatcgaagg attacctgta tatcgtgatt ctttcggcgg
    14701 aatcggaacc ccgacaagcg accatgaacg tacgaagatg gacctcgaaa ctactcatat
    14761 cctagccata gtcaacggtt ataacggaaa agaaggtttg caagaagctg ttgaaatgat
    14821 acagacctta ttaagaaact atacagaatc ggatggaggc gaaatcgtat tcttcgaata
    14881 attagaatga gtgctctaag aaaaaagaca tgaaaaacat acttatctta ctgacagttt
    14941 tattattgcc actgactgcc gccgggcagg ataaatcctc cttctctgcc cgcgaaatgg
    15001 ctgatgtacg ggtagctact cccggattat ttgctaaaag caatcatatc tatctgcatt
    15061 tggattctct gaaagatcac gaatatgctt tcccattacc cggaggaaaa gtaatctctg
    15121 cctatggaac tcgcggagga cattcaggaa cagacattaa gacctgtgca aaagatacga
    15181 ttcgtgctgc ttttgatgga gtggtgcgta tgtc
//
