LOCUS       c00088_gnlPro..        15157 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KABPKLGH_88.
ACCESSION   c00088_gnlPro..
VERSION     c00088_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 23:38:59
            Original ID  :: gnl|Prokka|KABPKLGH_88
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 72196
            Orig. end    :: 87353
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15157
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[82196:85169]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12973
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15157
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15157
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             667..2418
                     /locus_tag="ctg88_66"
                     /transl_table=11
                     /translation="MMKKYIFLMLVAVCLFSCKDDEKVRQTKSPEVAFTTDKEEYTLGD
                     IVYLTDESVETEGQIAEYFWHFGFDGEGNRATTKDASVLYKKAGTYVVKLTVTDEFGGY
                     ATASHTVVIRPTNRPPMADFSYNPAICKVNEKVKFTDKSTDEDGEVVAYEWDFGNGQTS
                     QEKDPEVTFTTAGFVTVKLTATDDRGATNTKQATLYVRNTSVSGLQILWTKTFETSSSL
                     RSISPAVGDNGDVYVSSNALHLYAYSPSGDQKWAFDLSKDGGAGDQGSSPMVDADGTIY
                     IGSSTTNKNISSSLYAIHPDGTQKWRYEIGIGTNIPYISPALARDGNILIGNRGTDGSV
                     HMVDRSSGRQLWRRKSPNGGANGGISVGQNGVVYSALSGANGFARTTEDGVNLSPNLGK
                     GNTAAAVYPAIDAQGNVYVAFSEGVIAAYDDQGNELWRYPATGTIGKIDQGGPAIGADG
                     TIYVGTKNPNAQVIALTKGGTKKWSYASSAEIGTTPAVDSEGNIHICDDGGNYIVLNAD
                     GTEKYRQQLGTKIWSSPVIADYGIVYVTYEENGACKLVAIDCGIEGPANSPWAQRGQNA
                     KRNALQK"
     CDS             2430..3335
                     /locus_tag="ctg88_67"
                     /transl_table=11
                     /translation="MLRKINLLIALTLLLAGGLKAQNHSDQIIANLQEPAARSVLVVSH
                     RADWRNAPENSLQAIQNCIDMGVDVIEIDLKKTKDGHLILMHDKKIDRTTTGKGYPADY
                     TLEELRQFRLKSGTGHKTAHLIPTLEEVMLLCKGKILVNIDKGYDYFKEAYAILEKTGT
                     VQQCIIKAGLPYEQVKAENGDVLDKVIFMPVVQLHKEGAEAIIDSYQKHMKPAAYELVF
                     DNDSQPVLDLIQKVRATGANLFINSLWPELCGGHDDDRAVELHQPDESWGWIINQGAKL
                     IQTDRPVLLLEYLRTKKLHD"
     CDS             3348..4742
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 154.8; E-value: 9.4e-48)"
                     /gene_kind="transport"
                     /locus_tag="ctg88_68"
                     /sec_met_domain="MFS_1 (E-value: 1.2e-47, bitscore: 154.8,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKQLINFYKVSSPRPCNRETLSSFDKCRLDSDTRINSDSRRLKY
                     LKWSTFLSATFGYGMYYVCRLSLNVVKKPIVDEGIFSETELGIIGSVLFFTYAIGKFTN
                     GFLADRSNINRFMTTGLLITALVNLCLGFTNSFILFAILWGISGWFQSMGAASCVVGLS
                     RWFTDKERGSYYGFWSASHNIGEALTFLIIASIVSVLGWRYGFFGAGIVGLIGALIVWK
                     FFHDTPESMGFPSVNVPKQKKEMSETETADFNKAQRQVLLMPAIWILALSSAFMYISRY
                     AINSWGVFYLEAQKGYSTLDASFIISICPVCGIIGTMFSGVISDKLFGGRRNVPALIFG
                     LMNVFALCLFLLVPGAHFWIDVLAMVLFGLGIGVLICFLGGLMAVDIAPRNASGAALGV
                     VGIASYIGAGLQDVMSGILIEGQKTVQNGVDVYDFTYINWFWIGAALLSVLFALLVWNA
                     KSKEVD"
     CDS             4869..5003
                     /locus_tag="ctg88_69"
                     /transl_table=11
                     /translation="MENSLNDELLCSLKDELREVTAQINVHSEKLMDLLDQKKESLVN"
     CDS             5012..5257
                     /locus_tag="ctg88_70"
                     /transl_table=11
                     /translation="MSHLTPVIIEYRGNPKQYVSVVLDAINLGRLTYDGVANCEQTFRA
                     LASVVDVISPKNGKTLSVETLVSYEKKKRAGEFEEK"
     CDS             5367..5669
                     /locus_tag="ctg88_71"
                     /transl_table=11
                     /translation="METLTEKEQDKIQYGLLLLKTQERLSTKFVKFVQDGVFELRTEYN
                     GNIYRVFFIFDDGNIVVLFNGFQKKSQKTPGSEIDKALKIKEEYYADKQSSNSRL"
     CDS             5635..5937
                     /locus_tag="ctg88_72"
                     /transl_table=11
                     /translation="MQINNHQIVDYDAVLDAKFGAEGTPERAEAEEKAYAFYTGQIIED
                     ARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCRIEFSMSL"
     CDS             5956..6087
                     /locus_tag="ctg88_73"
                     /transl_table=11
                     /translation="MVGNLKKITVFFKFPTVFLRKKKEKVRVGEGKFLTFVFFFRRK"
     CDS             complement(6176..8293)
                     /locus_tag="ctg88_74"
                     /transl_table=11
                     /translation="MEHFTIFQDFYRVIAEMTEEEIVSAISNGTYRETVEDVRRIFAEQ
                     GEKAANEKKIELPEITFSANYRGGRSNATLVKYLGYIVVDIDHQTQEALARILALAKKC
                     AHTRIAFISPKGMGLKIVVRVCRTDGTLPETIQEIEDFHHAAYHKIASFYAQLCGVEVD
                     TSGQDVSRTCLFSYDPDIYFNPDATAVIVEQPPMFFKSQKKKRASGKKKKTTAPDNNPL
                     TEQVALNYHSSHASLMVTLNYYHNKSEKYVTGNRNNYLHCLACMYNRYGVPQEEAAAFI
                     KSQFTDLPADEMDALIGSAYGHNEEFDTRKLNSTQKRILQIEQHIKENYDTRYNEVLHI
                     MEYRRRKTDTEQPEPFHILDEMMENSIWMEMNELGYSCTVKTIQNLIYSDFSSTYHPIR
                     EYLDSLPEWDGTDYIGILANSVHTSHQKFWVECLERYLVGMCAAATQDDVVNHTVLLLC
                     SEIQNIGKTTFINNLLPPELRAYLSTGLINPNNKDDLAKIAQAMLINLDEFEGMNGREL
                     NIFKDLVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVNSME
                     FIKINYAQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPE
                     RFEKVHYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIID
                     TEQVKSNRLYE"
     CDS             complement(8381..8611)
                     /locus_tag="ctg88_75"
                     /transl_table=11
                     /translation="MYYPDQPFHIRTYKKSELAHLYNPNVCLKVALQILRRWIVYNLPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             8805..9308
                     /locus_tag="ctg88_76"
                     /transl_table=11
                     /translation="MAMTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITS
                     RSTCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLIT
                     AAHIIFRPGKTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAP
                     DPAA"
     CDS             9329..9496
                     /locus_tag="ctg88_77"
                     /transl_table=11
                     /translation="MKEIVTKILDVIMFLVPFFGKRKRNRIVREVRFNATHKEVCNVKT
                     TEREKDDEKD"
     CDS             9483..9929
                     /locus_tag="ctg88_78"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDENGKAADTRTSRQKEAMHRLVSELL
                     QRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIEEFES"
     CDS             complement(10001..10729)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.2;
                     E-value: 4.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_79"
                     /sec_met_domain="Radical_SAM (E-value: 3.1e-29, bitscore:
                     94.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLVRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(10745..12973)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_80"
                     /sec_met_domain="Gly_radical (E-value: 3.5e-46, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1172.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLRNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             complement(13545..14021)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg88_81"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 4.1e-54,
                     bitscore: 174.8, seeds: 130, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDIKLACDVAEQVRTICDKHGNNPGELINILHEAQHLHGYLPEE
                     MQRIIASKLNIPVSKVYGVVTFYTFFTMTPKGKHPISVCMGTACYVRGSEKLLEEFKRV
                     LGIEVGETTPDGKFSLDCLRCVGACGLAPVVMIGEKVYGRLQPIDVKKIIEELE"
     CDS             complement(14040..15155)
                     /locus_tag="ctg88_82"
                     /transl_table=11
                     /translation="YTNRLLDDLANPDKVVIVQTAPAVRAALGEEFGFPPGTLVTGKMV
                     YALRELGFDYVFDTDFAADLTIMEEGSEILNRLTRYLNGDKSVRLPILTSCCPAWVNFF
                     EHHFPDMLDIPSTARSPQQMFGSIAKSYWAEKMGIPREKLVVVSIMPCLAKKYECARDE
                     FKVNGIPDVDYSISTRELARLIKRANIGFPLVLDSPFDNPMRESTGAGVIFGTTGGVME
                     AALRSVYEIYTGESLKNVNFEQVRGLNGVRRATINLNGFELKVGIAHGLGNARHLLEDI
                     RNGHNEYHVIEIMACPGGCIGGGGQPLHHGNSEILYARANALYREDANKPLRKSHENPY
                     IKTLYEEYLGKPLGEISETLLHTHYFNKSMD"
ORIGIN
        1 aaagacggta tcatcgtgtt gatgcacgat gaaacgatag accggaccac taccggaaca
       61 gggaaagtga aagatttgac ttatgagcag attcagtcct atcgtcttaa actggcagat
      121 ggaacgataa ccaatcatac agtaccttca ttatacgacg cactggtggc aggacgtgga
      181 aagatctttt tcgatttgga ctttctaaat aaagtatctc ccaaagagct ctatgatgtc
      241 gtgaaaagtt gtggaatgtt ggaccgtgtt tttttctata cctccaataa tcgggatgta
      301 ttgcagaata tcctgaatta ttctcctgcg ccgataccct atccccaatg tgaggatgaa
      361 gaacatgctg atttcctgtc acaacagccg ggagtgattt ttacccagat ttctttaagc
      421 aaaactttaa atggtggact gcctgcggcc atctcttcca aaggtttgtt cgtgtcaacc
      481 aatatgctcg atatgaacgg ctatacgtat gacactcaaa tgacgcaagg caattataca
      541 ggtgtcgatt tgatcttgtc aaaaggaatc agtatgatac agaccgatca tccccaattg
      601 ctggacgctt atttgaaaca aaaagggaaa agataatttg ttcaatcttt aataatgaat
      661 aaagtaatga tgaaaaaata tatatttctg atgctggtag ccgtttgctt attctcctgc
      721 aaagacgatg agaaagtgcg gcaaacaaag tcccctgaag ttgcttttac aactgataag
      781 gaagaatata cactaggtga tattgtttat ctgactgacg aatctgttga aacagaaggt
      841 cagatagccg aatacttttg gcatttcgga tttgatggtg aaggaaatcg ggctacgacc
      901 aaagacgcgt ccgtcctgta taagaaagca gggacttatg tcgttaaatt gacggtaaca
      961 gatgaattcg gaggatatgc gacggcatca catacggttg tgattcgccc gacaaatagg
     1021 ccgccgatgg cggactttag ttataatcct gctatttgca aagtgaatga gaaagtgaaa
     1081 ttcacagaca agtcaacgga tgaagacgga gaagtagtcg cttatgaatg ggattttgga
     1141 aacgggcaaa cctcgcagga aaaagacccg gaagtgacgt tcacaacagc agggtttgtg
     1201 actgtcaaac tgacggctac cgatgatcgt ggagcaacga ataccaaaca ggctacgctg
     1261 tatgttcgta acacttctgt ttcaggatta caaatccttt ggacaaaaac atttgaaact
     1321 tcctcttcct tgaggtctat atcccctgct gtgggtgaca atggagatgt gtatgtgtca
     1381 tccaacgctc ttcaccttta cgcttattca ccgtcgggag atcagaaatg ggcttttgat
     1441 ttgagtaaag acggaggagc tggtgaccaa ggttcatccc cgatggtgga tgctgacgga
     1501 acgatttata tcggttcaag cactacaaat aagaatatca gtagtagttt atatgccatt
     1561 catcccgacg ggacgcaaaa atggagatat gagataggca ttggaacaaa tattccgtat
     1621 atctctccgg ctttggcccg tgatggtaac atcttgatcg gtaatagggg aacagacgga
     1681 tcggtacaca tggtagaccg tagttccggc agacaacttt ggagacgtaa atctcctaac
     1741 ggtggtgcta acggaggtat atcagtaggc caaaacgggg ttgtttattc agccttgtcg
     1801 ggtgcaaacg gatttgcccg taccaccgag gatggtgtga acctgtctcc taatctgggc
     1861 aagggaaata ctgccgccgc cgtatatccg gctattgatg cgcaaggaaa tgtctatgtt
     1921 gcgttctcgg aaggagtaat tgccgcttat gacgatcagg ggaatgagtt gtggagatac
     1981 ccggctaccg gcactatcgg taagattgac caaggtggtc cggctatcgg tgcagatggt
     2041 acgatctatg tgggaacgaa aaatccgaat gctcaagtaa tagctttgac taagggagga
     2101 acgaagaaat ggagttatgc atcttctgcc gaaataggaa caactccggc tgtggatagt
     2161 gaaggtaata tccacatctg tgatgatgga ggcaattata ttgttctgaa tgctgatgga
     2221 acagagaaat acagacagca attgggaact aagatttggt catctcctgt aattgcggat
     2281 tatggtatcg tatatgtcac ttatgaagag aacggagcct gtaaattggt ggctattgac
     2341 tgcggaattg aagggcctgc taattctcca tgggcacagc gcggacagaa tgcaaaaaga
     2401 aatgccttac aaaaataaaa tagaaagata tgcttaggaa aataaattta ttgatagctt
     2461 taaccctcct gttggcagga gggttaaaag cccagaacca ttcggatcaa attattgcga
     2521 atcttcaaga accggccgct cgttcggtct tggtcgtatc tcatcgtgct gattggcgta
     2581 atgccccaga gaactcgttg caagccattc agaactgtat tgatatggga gtagatgtga
     2641 tcgaaattga tttaaagaaa accaaagacg gacatctgat tctgatgcat gataaaaaga
     2701 ttgaccgtac gactactgga aaagggtatc ctgccgacta tactcttgaa gaactgcgac
     2761 agttccgctt aaaaagtggt accggacata aaacggctca cctgatacct actctggaag
     2821 aggtaatgtt actttgtaaa ggcaagattc tggttaatat tgataaaggt tatgattatt
     2881 ttaaagaagc ttacgccatt cttgaaaaga ccgggacagt tcaacaatgc attatcaaag
     2941 ccgggcttcc ttatgaacaa gtgaaagcag aaaatggaga tgtgctggat aaagtcattt
     3001 tcatgcctgt cgtacagctt cataaagaag gagccgaagc tattattgac agctatcaga
     3061 agcacatgaa acctgctgcc tatgaactgg tatttgataa tgatagtcag ccggttctcg
     3121 atttgattca gaaagtgcgt gctacaggtg ccaacctttt cattaattct ctatggccag
     3181 aattatgtgg tggtcacgat gatgaccgtg cagtagaact tcaccaaccg gatgaaagtt
     3241 ggggatggat tatcaatcag ggtgctaagc tgattcaaac agaccgtcct gttcttctat
     3301 tggagtattt acgaaccaag aagctccacg actaaaagaa tttctccatg ttgaaacaac
     3361 taattaattt ttacaaggtc tcttcaccga gaccttgcaa cagggaaact ttgtcttcat
     3421 tcgacaaatg tcgtttggat tccgataccc gtataaattc cgatagtcgt cgtctgaaat
     3481 acctgaaatg gtctaccttt ctttcagcga ctttcggtta cggtatgtat tatgtgtgcc
     3541 gtcttagcct gaatgtcgta aagaaaccta ttgtagatga aggaattttt tcggaaacag
     3601 agttaggcat cataggttcc gtattgtttt tcacctatgc gatcgggaaa ttcacgaacg
     3661 gtttccttgc cgaccgcagc aatatcaacc gttttatgac taccggttta ttgataactg
     3721 ctttggttaa tctttgtctc ggttttacta attcttttat cctgttcgct atcctttggg
     3781 ggattagcgg ctggtttcaa tctatgggag cagcctcttg tgtagtaggg ctttcccgtt
     3841 ggtttacgga taaggaacgc ggttcatact atggcttttg gtctgcgagc cataatatcg
     3901 gcgaagcgtt gacttttctg ataatagcct caattgtcag tgtgttgggc tggcggtatg
     3961 gtttcttcgg agccggtata gtgggattga taggagcgtt gatcgtctgg aagttcttcc
     4021 atgatactcc cgaaagcatg ggattccctt cggtgaatgt tcccaaacag aaaaaggaaa
     4081 tgagtgagac agaaacggct gattttaata aagcacagcg tcaggtattg ctgatgcctg
     4141 ccatttggat actggctctt tcgagtgctt ttatgtatat cagtcgttat gctatcaata
     4201 gttggggcgt tttttatttg gaagcccaaa aggggtattc cacattggat gccagtttta
     4261 tcatttctat ttgtccggtc tgtggtataa tcggtactat gttttcaggt gttatttctg
     4321 ataagttatt tggtggacgt cgcaatgttc ctgcgttaat tttcggattg atgaatgtgt
     4381 ttgctctttg tttgtttctc ttagttccgg gagctcattt ttggatagac gtgttggcaa
     4441 tggttctttt cggtttaggt atcggagttt tgatctgttt tctgggtggt ttgatggcag
     4501 tggatattgc tccccgtaat gcttcgggtg ctgcattggg agtagtcggc attgccagtt
     4561 acatcggtgc cggattgcag gacgtgatga gcggtatact gatagaaggg caaaagactg
     4621 ttcagaatgg agtagatgtt tatgacttca cctatatcaa ttggttttgg attggtgctg
     4681 ctttgctttc tgtgttgttt gctttgctgg tatggaatgc aaaatcaaaa gaagtggatt
     4741 aaagtgagta cattaggtta gaatataagt ctttgttttc gaggtattag acaccattcc
     4801 gggaagtaag taatgattgc ttatctttct ggaatggctt ttttataatc aattaaataa
     4861 aaagttttat ggaaaattca ttgaatgatg aattattgtg ttcattgaaa gatgaacttc
     4921 gtgaagtaac tgcacaaatc aatgtgcata gtgaaaaatt aatggatctg ctcgaccaaa
     4981 aaaaagaatc gttggtcaac tgactcgaga gatgtcgcat ctcacgcctg tcatcatcga
     5041 gtatcgggga aatccgaagc aatatgtctc tgttgtgctc gatgccatca atctgggtag
     5101 gttgacgtat gacggagtag caaattgcga acagactttt cgtgcgttag caagcgttgt
     5161 agatgtgata agccctaaga atgggaaaac gcttagtgta gagacgctgg tgtcttatga
     5221 gaagaaaaag cgtgcaggag aatttgagga aaaataatat aaaataaaaa gatgattgtt
     5281 gtatagttga acaacaattc gcatatttgc agtatggaaa gcctcaacgt aacctccgta
     5341 catacggagg ttacgttgag gctttcatgg agactttaac cgaaaaggaa caagataaaa
     5401 tccagtatgg actactcttg ttgaaaacac aagaaagact ctccactaaa tttgtaaaat
     5461 ttgttcagga cggagttttt gaacttcgta cagaatataa tggtaatata taccgggtat
     5521 ttttcatttt tgatgatgga aatattgtag tgttgtttaa tggctttcaa aagaagtcgc
     5581 aaaaaacacc gggtagtgaa atagataaag cattaaaaat aaaggaggaa tattatgcag
     5641 ataaacaatc atcaaatagt agattatgac gctgttcttg atgcgaaatt tggagcagaa
     5701 ggtactcccg aacgtgcgga agcagaagaa aaagcgtatg ctttctacac cgggcaaatt
     5761 atcgaagacg caaggaaaaa ggctaagatt actcaagcag agttagcccg gcgtatcggt
     5821 tccgaccgtt cttatatttc aagagtggaa agtggtcaga cagaacctaa ggtttctact
     5881 ttctatcgca tcatgaatgc gttaggttgt aggatcgaat tttcgatgtc tttataagaa
     5941 gcgattaaaa aaaacatggt gggaaatttg aaaaagataa ctgtcttttt caaatttccc
     6001 accgtttttt tgaggaagaa aaaggaaaag gtgagggtag gtgagggtaa atttctaaca
     6061 ttcgtatttt tttttagaag aaaatagaag aatagaaata agaaatataa aaatgaaaag
     6121 ttgcaaaagt accctcacca accctcacct ttttgcgtgc gaaggagatg aaatcttatt
     6181 catatagcct gtttgatttc acctgttccg tatcaataat gaatacagtg tatcttctcc
     6241 cgttttttcc cttatgaaat tcgaagccgt gtttggacat cacttttcct agttgggctt
     6301 tggttccgtg agaatattga taccccgtcc gttcgcgaat caattccgca atttcagtga
     6361 ccgtcagata atgcaccttt tcgaaacgtt ccggtttgcg gatatgtgtc aacaccagtt
     6421 cttcttccgg tgagtggaaa atgaaatcct cgttgttctc ttcaatccgt gagttttccg
     6481 actgggtgaa ccaatactga taccccggct tgttgagcag atacttgatt tgtgcataca
     6541 actgcgcgta gtttattttg ataaactcca tcgagttgac atgaaagcag agaaaacggc
     6601 ggttacctgt ggtgtcgtga agcacttcct gataattgca tgtgccggca aaagaagccg
     6661 tgtgaggaaa gttctgcgaa cgccgcgcgt atggcaggcg gatgctgatt actttgcggg
     6721 taactaaatc cttgaagata ttcagttccc gtccgttcat cccttcaaac tcatccagat
     6781 tgataagcat tgcctgcgct attttggcca gatcatcctt gttgttcggg ttaataagac
     6841 cggtagaaag ataggcgcgc aattcgggcg gcagcaggtt gttgataaac gtagtctttc
     6901 cgatgttctg tatttcgctg caaagcaaca aaacagtgtg gttcaccaca tcgtcttgtg
     6961 tggcggcagc gcacattccc accagataac gttccagaca ttctacccaa aatttctggt
     7021 gactagtatg cacgctgttg gcaaggatac cgatataatc cgttccgtcc cattcaggca
     7081 gcgagtctaa atactcgcga ataggatggt aggtgctgct gaagtcggag tagatcagat
     7141 tttgaatcgt cttgacggtg cacgaatagc ctagttcgtt catctccatc caaatgctgt
     7201 tttccatcat ttcgtcgaga atatggaaag gttccggttg ctccgtgtcc gttttccttc
     7261 tgcgatattc catgatatga agcacttcgt tgtagcgtgt atcgtaattt tctttgatat
     7321 gttgctcaat ctgtaatatt cgcttctgcg tactattcag cttgcgggtg tcgaattcct
     7381 cattgtgtcc gtaagcactc ccgatcagtg cgtccatttc atccgcggga agatcggtga
     7441 actggctctt gataaaagct gccgcctctt cctgggggac gccgtagcga ttgtacatac
     7501 aagccaggca atgcaggtag ttgttccggt tgccggtgac gtacttttcg gatttattgt
     7561 gataatagtt cagagtcacc attaaggaag cgtgcgagga atggtagttg agtgccactt
     7621 gttcggtgag gggattgttg tctggtgctg tcgtcttttt ctttttgccg gatgcccttt
     7681 tcttcttttg agacttgaag aacatcggtg gctgttccac gatgacagct gtggcatcgg
     7741 gattgaaata aatatccgga tcgtaagaga acaggcaagt gcggctgaca tcttgtccgg
     7801 aagtgtcgac ctcaactccg cagagctggg cataaaagga agcgattttg tgataagcgg
     7861 catgatggaa atcttcaatt tcctgaatcg tttcgggcaa tgtcccgtcc gtccggcata
     7921 cacgtaccac gattttcagt cccattcctt tgggactgat gaaagcgatg cgggtgtggg
     7981 cacacttttt tgccagtgcg aggatgcgtg ccaatgcttc ctgtgtctga tggtcgatgt
     8041 ctaccacgat gtatcccaga tacttgacga gagttgcgtt tgaacgtcct ccccggtagt
     8101 tggctgaaaa ggtgatttcc ggtagttcta ttttcttttc gtttgctgct ttctcgcctt
     8161 gttccgcgaa gattcggcgc acgtcctcca ctgtttcccg gtatgtgccg ttgctgatgg
     8221 ccgatacgat ttcttcttct gtcatttcgg ctatgacgcg gtaaaagtct tgaaagatgg
     8281 taaaatgctc catgttggtt tgttcttttt aatttgcggt tgcaaagaaa tttgtttgta
     8341 aaataataga atggaacttt tcgttttttt gattaagttc ctagggttct cccaaatagc
     8401 gtatgatcgt tgccacttgc cggggagaga gaaggcggtt gcgggcacga tagccttctt
     8461 gttcgagttc ttgcaggagc ggaaggttgt agacaatcca acgacgtagt atttgtaagg
     8521 ctactttaag gcatacgttg gggttgtaaa gatgagctag ttccgacttt ttataagtgc
     8581 ggatatgaaa cggctgatcc ggataataca tgatgaataa tgtttgattt atgctataaa
     8641 gttactgaaa attaatggtt tattaaaaga ataacgtcat tattattcat agaatatcag
     8701 gaaacttcgt tggggaatcc ggagggtgaa aaatgtgtta tctttatgtc gttaacaaat
     8761 aaggaacgcg ttcgaaatgt gtgaaatctt aaaattattt tattatggca atgacagtaa
     8821 cttattcagt agtgccgcgc aagaatcctg ccaaaaagga tgagtcggca aagtattatg
     8881 cgcaggcaca ggcttcggga gagttggatt ttgaagagtt gtgcgaggga atcacgagtc
     8941 ggtctacctg tacggagaca gatgtgcgtg ccgccatttc gggtattctt tatgaggcga
     9001 agcgtgcgtt gaaagcggga agaatagtcc ggctgggtga tttgggcagt ttgcagatcg
     9061 ggttgaacag tgaaggagct gtgtcggtca aggagttttc aagttcgctg attacggctg
     9121 cccatattat tttccgtccc ggaaagacgt tggcggacat cacgaagatt cttagctacc
     9181 agcaagtaac gacgcgtgcg gtggctcaaa cgggcggtag cggcaatgaa ggagaagacg
     9241 atgacaaagg ttccggtggc ggttcagacg gtggtggaag cggagaagct ccggatccgg
     9301 cagcatgata actttaatat tggatcaaat gaaagaaatt gtaactaaga ttttggatgt
     9361 aatcatgttc cttgtgcctt tcttcggaaa aagaaagcgg aacagaattg tgagagaggt
     9421 gcgcttcaat gctacccata aagaagtgtg taatgtgaaa acgacggaaa gggagaagga
     9481 cgatgagaaa gattagtctg attgtgattc actgctctgc tacccgtgtc gatcgcgact
     9541 tcacggcgaa ggatgtggac actgcccatc gctttcgggg cttttcgtgt tgggggtatc
     9601 attattatat ccgcaagtcg ggacagatag aaccgatgag ggatgaagat acggtgggtg
     9661 ctcatgcacg cggttttaat gcgattagtt taggggtgtg ctatgaaggc gggctggatg
     9721 agaacggaaa ggcagcggat acacgtactt cccgccagaa agaggcgatg catcgtctgg
     9781 taagcgagtt gttgcagcgt tatccggatg caaaggtggt cggtcaccgg gacttgagcc
     9841 ctgacaccaa ctacaacgga attgtagacc cctgggaacg gatcaaagaa tgtccctgtt
     9901 ttgaggtgat tgaagaattt gagagttgag aatggagagt tgagagttgg ctgcgcactg
     9961 ttatactgca tagttaactc tcaattctca acttcttcaa ctaattgacc accacagtag
    10021 tgaaatactc tttaaatacc tccgcggctt tttcaagttg ttcgggggta ttttctttta
    10081 cgtctttcag tttgtattcc tgctccatcg cttcatactt atgtacgcct aatgtatgat
    10141 aaggcaggat ttccactcgt tgcaccatct tatattttcc cagagcctct cctaaacggc
    10201 ggatgtcttc ttcgaaatcg ctgtatccgg gcactaatac ataacgcagc cagaaaggtt
    10261 tctcgttttc ttccagccat gctgccgtgc ggatggtttg ctcgttactt cttccggtca
    10321 gtgcctgatg gcgtgccgga ttgaactctt taatatccag caatacaaga tccgtcagtt
    10381 tgaaaagttc ttctacttct tcgttccaga taccgccgtt gctgtctatg catacatgta
    10441 ttcccttttc tttcagttca cgcaccagag gaaccagtgc tttggcctga aacgtaggtt
    10501 ctcctccgga gaaagtgact cctccgcgtt tcccgaaaaa aggacgttgg ctcatagcca
    10561 tgcggacgat ttcttccggt ggggtaggtg tacctccttt tccggctatc gtgtcgggat
    10621 tggcacaata caggcagcgg aaattgcatc cttgaagaaa aacgacgagc cgtaagcccg
    10681 gcccgtcgaa tgttcccata ctttcgtatg aatgtacgtt tatcgtcata ttgagtagat
    10741 ctgattacat acgttcgtgg aagctacggc tgattacttc caattgatgt tcgcggctca
    10801 acttcacgaa gtttacggca taaccggaaa cacggatggt aagctgcgga tatttttccg
    10861 gatgttccat ggcgtcgtaa agcatttcac ggttcagtac gttcacgttc aggtggtgag
    10921 cgcctttggt gaagtaacca tccatcattg tcaccagatt ttctacgcga tcctcttcag
    10981 tagctcccag agatttcgga acgatggaga aggtgttgct gataccgtct tgtgagtcgc
    11041 ggtaacgtaa tttcgctacg gaactcaaag aggcgatagc accgttcttg tcacgtccgt
    11101 gcatcgggtt ggctcccgga gcaaaagcga cacctttggc gcgtccgtcg ggagtagcac
    11161 ctgtcttctt gccatacatc acgttggaag tgatggtgag caaagataaa gtaggacggg
    11221 catttttgta aaccggaagt ttcttcaatt cttcgctgaa gaaatagacc aggtcaacac
    11281 ccaggtggtc taccttgtcg ttgtcattac cgaagcaagg gaattcgcct tgaatatcga
    11341 aaccttctgt cagaccgatg tcgttgcggc gtgcggttac tttggcatat ttgatggccg
    11401 acagtgaatc gagggcgata gaaagtccgg ctacaccata agcaaggttg atgcgtgggt
    11461 tggtatctac aagagccatt tgggcttttt cgtagtaata cttatcatgc atataatgga
    11521 tgatgttcat cgcttcgttg taaacacggg cgatttctgt caataccttc ttgtagttgc
    11581 tcattacttc ttcgaagttc agtgtgtcgc tggttagtac ggggatattt ttcaccatta
    11641 ccgtaccggt gttttcgcaa cgtccgccgt tgatggcaag cagcagggct tttgccaggt
    11701 tgcaacgtgc gccgaagaat tggatttgtt ttccgatttc ctgataagat acgcagcatg
    11761 cgattccgta atcgtcagac tggcgcactt cacgcatcag gtcgtcgttt tcatattgga
    11821 tggaagaagt gtcgatagat acttttgcgc agaattcttt gaatccttcc ggcagttccg
    11881 ggctccacaa tacagtcagg ttcggttccg gtgaagggcc gaggttgtag agtgtttgca
    11941 ggaagcggaa agaagtcttt gtcaccttgg tacgtccgtc gttgaggcgt ccgcccagag
    12001 attcggttac ccatgtcggg tcgccggcaa agatgtcgtt gtaagattgc atacgcaggt
    12061 ggcgcaccat acgcagtttg atgacaaact ggtcgatcag ctcctgtgcg aaagattctg
    12121 tgatggttcc tttgctcaat tcatattcca tataaatgtc gaggaacgaa gagacgttac
    12181 ccagtgacat ggcagcaccg tcttgttctt ttacggcagc aaggtaagcc atgtacaccc
    12241 attgtactgc ttcttgtgcg gtgtaggcag gacggctcaa gtcgagtccg tagtattcgc
    12301 ccattacctt catgtccttc aatgccttga tttgctctgc cacttcttcg cgcaggcgga
    12361 tgcgggcttc ggtcatcgga ccggtaaggt tacgcaaatc ttcttttttt gcctcaatca
    12421 gtcggtcgat accatagaga gccatacggc ggtagtcgcc gatgatacgt ccgcgggcat
    12481 agttgtcagg aagtccggtg aggaatccca gagaacggaa cgaacggatt tcttcggtat
    12541 atacgtcaaa tactccgtca ttgtgcgtct tgcggtagtg agtgaatata tcttttacac
    12601 ggtcgtccac ttccacgccg ttttcgtggc aggctttgct caccacgttg atacctccga
    12661 aaggtttgat tgcacgtttc agaagttcgt ctgtttgcag accgacgatc agttcgtttt
    12721 ctttgtcgat atatccggct ttatgagaag tgatggttga gacggtgaca ttatccagtg
    12781 agcgtactcc gttattggct ctttcttctg ccagtgcttc gaggcagcgg ttccatacag
    12841 cttttgtgcg ttcggtaggt ccttcgagga aagaagcatc tccataatac ggagtgatgt
    12901 tgtgactaac gaaatctctt acgttgattt ctgtgctcca aagaccgtct ttaaagatct
    12961 tatttaattc cataaatgat aaaattagag gttgtagtta tccttttctt tagagcgcac
    13021 aaagttacaa cgttttttca tataatcagc ataaatatgc tctattttat gcttttcaac
    13081 ataaaatacc tagatattgc tattctttgg aaatgatgtt cgtgattttt ttttgtgaaa
    13141 actcttgtaa gtttaaaata tattcgtacc tttgcaccgc ttttaacgaa aagcacttct
    13201 gataaagaag ttttggagag gtggcagagt ggtcgattgc ggcggtcttg aaaaccgttg
    13261 tactgcgagg tacccggggt tcgaatccct gtctctccgc taggatagca gcttttaagc
    13321 tgctatttct tttgtggaaa atatatttcc attgtttgtt tccttattgg aaaataagga
    13381 gaggtgctcg agtggttgaa gaggcacgcc tggaaagcgt gtatactcct aaagggtatc
    13441 acgagttcga atctcgttct ctccgctttt ttgtttgttg ttaaaaaaat gtttgaaagc
    13501 ggctgccttg atttttcaaa gcagccactt tttattccgg acatttattc caactcttcg
    13561 ataatcttct tcacatctat cggttgcaat cttccgtaca ctttctcgcc aatcatcact
    13621 accggagcca gtccgcaggc acctacgcag cgcaggcagt ccaatgagaa ttttccatcc
    13681 ggtgtggttt cgccgacttc gatgcctagt acgcgtttga attcttcgag caacttctcg
    13741 gagccgcgca cgtaacatgc cgtacccatg cagacggaga tgggatgttt ccctttcggg
    13801 gtcatggtga agaaggtata gaaggtgacc actccatata ctttcgatac ggggatattg
    13861 agtttggaag cgatgatgcg ttgcatctct tcgggcaggt agccgtgcag gtgttgcgct
    13921 tcgtgcaaaa tattgattag ttcgcccggg ttgtttccgt gcttgtcgca aatcgttcgg
    13981 acttgttctg ccacatcgca ggctagtttt atatctgaca taatactctt cgtttaaagt
    14041 taatccatag atttgttgaa atagtgcgtg tgcaatagcg tttccgatat ctcgcccagt
    14101 ggtttgccga gatattcttc gtacaaggtc ttgatgtacg gattctcgtg cgatttgcgc
    14161 aaaggcttgt tggcgtcttc gcggtagagt gcgttggcgc gtgcatacaa tatttccgag
    14221 ttgccgtgat gcaacggctg tccgcctcct ccgatgcaac ctccggggca agccataatt
    14281 tcgattacat gatattcgtt gtgcccgttc cgtatgtctt ccaatagatg gcgggcgttg
    14341 cctagtccgt gtgcgatgcc tacttttaat tcaaatccgt ttaggttgat ggtagcacgc
    14401 cggacaccgt taagtccgcg tacttgttcg aagtttacat ttttcagaga ttctccggta
    14461 tagatttcat aaacagaacg gagggcggct tccattacac cacctgttgt accgaaaata
    14521 acgccggcac cggtcgactc acgcataggg ttgtcaaacg ggctgtccag taccagcggg
    14581 aagccgatat tggcgcgttt aatcagtcgt gccagttcgc gggtggaaat agaataatct
    14641 acgtcgggaa taccgttcac tttaaattca tcgcgggcac actcgtactt ctttgccaga
    14701 cagggcatga tggatacgac taccagcttt tctctgggaa ttcccatctt ttccgcccaa
    14761 taggatttgg cgatagagcc gaacatctgt tgcggtgaac gggcggtgga tggaatgtcc
    14821 agcatatccg ggaagtgatg ttcgaagaag ttcacccatg ccggacagca ggaggtcagg
    14881 ataggtaacc gtacggactt atctccgttg agatagcgcg tcagacggtt tagtatttcc
    14941 gatccttctt ccatgatggt gaggtcggcg gcaaagtcag tatcgaatac atagtcgaat
    15001 cccagttcac gcagggcata aaccattttt ccggttacca gtgtgccggg aggaaaaccg
    15061 aattcttcgc ccagggcagc acgtacggca ggggctgttt gcacaatcac cactttatcc
    15121 gggttagcta agtcgtcgag caggcggttc gtataat
//
