LOCUS       gnlProkkaAGOLCJGC_164  15221 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AGOLCJGC_164.
ACCESSION   gnlProkkaAGOLCJGC_164
VERSION     gnlProkkaAGOLCJGC_164
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 23:01:25
            Original ID  :: gnl|Prokka|AGOLCJGC_164
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15221
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..189
                     /locus_tag="ctg164_1"
                     /transl_table=11
                     /translation="MYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARANPLRKQYY
                     EKRDDSDKLKLDTVDED"
     protocluster    1..15221
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4870:5221]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4871..5221
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15221
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15221
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             199..1440
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg164_2"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             1427..1954
                     /locus_tag="ctg164_3"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             1960..2733
                     /locus_tag="ctg164_4"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQPAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             2740..3135
                     /locus_tag="ctg164_5"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             3385..4773
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 91.6; E-value: 6.8e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg164_6"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMNDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             4871..5221
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg164_7"
                     /sec_met_domain="PqqD_RRE (E-value: 4.9e-11, bitscore:
                     32.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.2e-17, bitscore: 53.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYELRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(5240..5524)
                     /locus_tag="ctg164_8"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(5562..6629)
                     /locus_tag="ctg164_9"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKMPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             complement(6703..8214)
                     /locus_tag="ctg164_10"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYST
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWQLVSE"
     CDS             complement(8489..8605)
                     /locus_tag="ctg164_11"
                     /transl_table=11
                     /translation="MRNTLKYYENKVAFEPKYGRTYEKYRFEKVFLIRYLFD"
     CDS             9276..9500
                     /locus_tag="ctg164_12"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             9693..11237
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 46.8; E-value: 2.5e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg164_13"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASTLDNTN
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKADHISHPKMDKRTKVRNTLVITILTIALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDIFGWEMPASW
                     FQSFNPLFVVVLAYIMPGVWGFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAVP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             11278..11814
                     /locus_tag="ctg164_14"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             11874..12443
                     /locus_tag="ctg164_15"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             12533..13696
                     /locus_tag="ctg164_16"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAET
                     GEYLCDVTEDGQEVVLLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     VTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEDIVYEYEEDVDDDDDIDYEYEEEDWEEK"
     CDS             13693..14505
                     /locus_tag="ctg164_17"
                     /transl_table=11
                     /translation="MISLTKHNELKGYKSLEAYPEVAHFVTTRHEGISTGAYGSFNCSP
                     YTNDSCMNVNRNQSWLFQCMNHQIKELFIPEQNHGCASLIINESFFKESLEMRRLLLRG
                     MDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSHVMDHLNKMF
                     GTQGEDVIACIGPSISLESFEVGDEVYDAFEESGFDMSLISMKKKETGKYHIDLWEANR
                     IELLNLGVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRTLSGIMIRK"
     CDS             14556..15221
                     /locus_tag="ctg164_18"
                     /transl_table=11
                     /translation="MFEIKVSKEIKDACPVFAGAAVYAAVKNTAYSEGLWQEINAFTGQ
                     LTSTTQMEDIKHQPVIFATREAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDL
                     INLVSLRTGHSIGGFDADKIQGTHLELGIGKAGEPFEGIGRGVLNIEGLPVYRDSFGGI
                     GTPTSDHERTKMDLETTHILAIVNGYNGKEGLREAAEMIQTLLRNYTESDGGEIVFFE"
ORIGIN
        1 gcatacgata ttgcaggtaa gggagtggct tgtgaagatt ctttccgtca ggcaatctat
       61 gttgccatcg acgtgttccg taatcgtcag cgggaaaaag tggctcgtgc caatccgttg
      121 cgtaaacagt attacgagaa acgtgacgat agtgataaac tgaagctgga tacagtagac
      181 gaagattaaa aacgagtgat gacgaaagca gagatacaac aagtgaaaca gcgtttcggt
      241 attattggaa atactgaagc attgtcgcgc gccatagatg ttgccattca ggtagctcct
      301 accgatttgt ctgtgctgat taccggagaa agtggagtcg ggaaagaaag ttttccgcag
      361 attattcatc aatatagccg gaggaagcac gggcagtata ttgctgtcaa ctgtggtgct
      421 attccggagg gtacgattga ttccgaactg ttcggacatg agaaaggtgc gtttaccggt
      481 gcgattggcg aacggaaagg gtactttggc gaagctgacg gcggtactat ttttcttgat
      541 gaagtagggg agttgccgat gtctacccag gcacgtttgc tccgtgtact ggagagtggc
      601 gagtttatga aagtaggttc gtccaaagta caaaaaacgg atgtgcgtgt ggtggcggct
      661 accaacgtca atctgacaca agcgattgca gaaggacgtt tccgtgaaga tttatattac
      721 cggttgaata cggtgcctat ccagataccg cctttgcgtg aacgtggtga cgatgtgctc
      781 ctgttgttcc gtaagttttc cgcagacttt gcagagaaat accggatgcc tgctattcag
      841 ttgacggagg atgcgaagaa agagttgttg gcttacccgt ggccaggaaa cgtgcgtcag
      901 ttgaagaata tcaccgagca aatatctatc attgaaacca atagggagat ctctgctgct
      961 atcttgcaga attatcttcc cgcacaaaat acgcaacgtc ttcccgcgct gatgggaacg
     1021 cgtgagagta aaggctttga gagcgaacgg gagattcttt attctgttct gttcgatatg
     1081 cgccaggaag tggcggagct gaagaagatg gtgcacaacc tgatggcgga acgtgccgga
     1141 caggtggggc aggtaggaca aatgggaacg gtggttacta ctccggtagt gacggcgcat
     1201 caaccttcgg tacctgctat cattcacacc atgcagccca cggtttgcaa ggatgatgat
     1261 gacatacaag acacggaaga atatgtagaa gaatctcctt tgtcactgga cgaagtggag
     1321 aaagaaatga tacgcaaagc acttgagagg catcatggaa agcggaagag tgcggccaag
     1381 gacttgaata tttccgagcg tacactctat agaaaaataa aagaatatga attggattaa
     1441 gaaaataata cgccctttgt tactgttcgg cttgccgttg gtagtcattg cgtgcactgt
     1501 ttcctataag tttaacggat cgtctatcaa ttatgataag gtaaagacca tttcgatagc
     1561 cgacttcccg atcaagtcgg agtatgtgta tgctccgttg gcaaccaagt ttaatgagga
     1621 cctgaaagat atcttcatcc ggcagacccg tctgcaactg ctcaagccga gtcaaaatgc
     1681 cgacttgcag attgacggag aaatcacagg ttacaatcag tacaatcagg ctgtatctgc
     1741 cgacggttat tcttcggaga cgaagttgac tatcaccgtt aatgtacgtt ttgtcaacaa
     1801 caccaatcat gccgaagact ttgaacaaca gttttctgcg ttccgtacct acgactctag
     1861 ccagttgctg actgccgtac aggacggatt gattgctgaa atgtctaaag agatcaccga
     1921 ccaaattttt aatgcaactg tagcaaactg gtaatataaa tgacttctgt taactttcaa
     1981 caatggattc agcatcccga gacgctgaat agggatactt tgtacgaact gcgcaatctt
     2041 cttgcgaggt atccgtattt tcagtcactt cgtctgctgt atctgaagaa tctgtatatt
     2101 ctccatgata ttagttttgg tggagaactg cggaaagcag ttctttacat tgcagacaga
     2161 cggcagttgt tccggttgat tgaaggtgac cgctatgatg tgcaggcacg gaaaaaggga
     2221 gtacctctca cggaggtgct gaaagacgaa ccgtccgtag accgcacatt agcattgatc
     2281 gacgctttct tgtccacagt acccgaagag gtgactgccc gcaccagctt cgactattcg
     2341 atggattaca cctcttatct tttggaggag actccggcca cggaacagcc ggccgaagaa
     2401 acgcccaaac tcaaaggcta cgaactgatt gacgacttta tagaaaagag cgagagcgac
     2461 tctcccctct gcaagaaacc tttaagagaa gaaatgccat cttcgccaac ctcttcggac
     2521 gaacttaccg aagaagaaac gatgaaggaa gaagaggaag atgacagctg ttttacggaa
     2581 actttggcaa aaatctatgt taaacagcaa cgatattcaa aagctcttga aataattaaa
     2641 aaattaagct tgaaatatcc aaaaaaaaat gcttactttg cagaccaaat cagatttttg
     2701 gagaaattga ttattaacgc taattcaaaa taactaaaaa tgtacttatt attcgttatc
     2761 ttaatggtta ttgcagcctt gttgatgtgt ttcatcgtgc tgattcagaa ctcaaaagga
     2821 ggcggacttg cttctggttt ctcttcatct aacgccatca tgggcgtgcg caagactaca
     2881 gattttctgg aaaaagcaac atggggctta gctatcttca tggtggtaat gagcattgct
     2941 actgcttatg tagttcctcg ctctgctgtt gctaaagacg cagtgttgga acaggcacag
     3001 aaagaacaac agactaaccc gtataactta cccgcaggta cggctgcgcc gcaaactgaa
     3061 gctcctgcta ccaatgcacc tgctacagaa actccggcac cggctactga aactcctgct
     3121 cctgcagcag agtaattcac tccgttgtca ggtaagactt tggggtaaaa ccattaatgg
     3181 gaaggtgcag acggatgctg catttctttg atatttaagt gcggattacg cagattacac
     3241 ggattttcaa tcttccgcgt ggtcagtgta atccgcactt aactttttct tgtaaaaaca
     3301 atctcttttt gatagaaaca aacgagattt aactaccttt gttggtcgta tgaagattat
     3361 taactactat ttttaaatat aacaatgaca gaacatttga aacagaaatt gaatgactcc
     3421 gccgtactcc gatggagtgt tctagcattg gtcgcattta ctatgctatg cggctatttc
     3481 ctcaccgacg taatgtctcc tctaaaaccc atgcttgaga aagaactact atgggacagt
     3541 cttgattatg gtttcttcac aagtgcttac gggtggttta atgtattcct attgatgctg
     3601 attttcggtg gtatcatttt ggataagatg ggagttcgtt ttaccggaat gggagcttgc
     3661 ttattgatgg tgtttggttg tggattgaaa tactatgcga tttctactac ttttccggaa
     3721 ggtgccatgc tcttcggatt caaaacacag gtaaccctgg ctgcattggg gtatgctatc
     3781 ttcggtgtag gtgtggaaat tgccggtatc acagtttcca aaattatcgt gaaatggttc
     3841 aagggtaagg aaatggcatt ggctatggga cttgaaatgg ctacggcacg tatcggaaca
     3901 actctggcaa tggtgctcac ggttcctttg gccgactttt tcggatctac ggatgagagt
     3961 ggcacatttc ataccaatat tcctgctccg attttgtttt gtctgattat gttgtgcgtg
     4021 ggtacgattg ctttcttcct ttatactttc tatgataaga agttggatgc ttctttggat
     4081 gcagaaggat tggagccgga agagccgttc cgtatgaatg atattgtgta tatcattacc
     4141 aataaaggat tctggctgat tgcattacta tgtgtattgt tctactcggc tgtattcccc
     4201 tttatcaagt atgctgccga cttgatggtg cagaagtata acgtagatcc gaagttggcg
     4261 ggaacgattc ccggattgtt gccgattggt gcgattatcc tgactccgtt gttcggctcg
     4321 ctttatgacc gtattggtaa gggagccaca ttgatgataa tcggatcagt gatgcttatt
     4381 tttgtgcata cgatgtttgc tctgcctata ctgaatatat ggtggtttgc tactatcatc
     4441 atgattatat tgggatttgc cttctcgttg gtgccttcag ctatgtggcc gtctgttccg
     4501 aagattattc cggaaaaaca gttgggtacc gcatatgcat tgattttctg ggtacagaac
     4561 tggggattga tgggtgttcc tttgttgatc ggatgggtgt tgaatactta ttgcaaaggt
     4621 ccggtagtag acggtgcaca gacttatgat tacacgttgc cgatggctat ttttgctctc
     4681 tttggtgtgc ttgctctgat tgtggctttg atgttgaagg cagagaacaa gaagaaggga
     4741 tacggtttgg aagaggcgaa tatccaaaag taactaggaa attcaatacc taaagtaaca
     4801 aaggaatttt gtatcaaggt gtaaacagaa gagtatcagt atgaatactc tgaaataaaa
     4861 aataagaagt atggctgcca aagagaaaat caacctgtta gaggtcattc cctgtcgcag
     4921 tgaacatatt acagcagaaa gggaagggga gacaattgtg ctctcctttc cccgttttaa
     4981 atatccgtgg atgcaacgct tccttgtgcc aaaaggaatg tcgaaagaac ttcatgtgaa
     5041 attggaagaa cacggtacag ctgtatggga actgatagat ggaaaacgca atgttcgtga
     5101 gattatagaa aaactcgcag accactttca aaatgaagag ggctacgagt tgcgtgtatc
     5161 ggcttatctt tctcaaatgc agaaagatgg atttataaaa ctggtgatac cagtcgtata
     5221 aataggaact tattattatt tatttgataa atacagccca aagtatgacg gcaattgcta
     5281 tcaggactcc catgataata agcgttcccc aaacaaaata attgctgtct ttctctttct
     5341 ttttctccga gtcgtggatg atacgttcca tttcttcggg ggtggtgttg ggtagtggat
     5401 aaggttcgtt tgcacggttt agatgcttca acttatcgtt agcacgttca cgacgtaggc
     5461 gggaagcttc ccgtccctct tttattcggc gtatcatgtc gaatgcatgt ccttcaccaa
     5521 ccatattctt tgttttttag aagttcactt ccttcgtttt tctatttccc ttcttctctg
     5581 tccactttga gcaatcctcc cgtattcgga tcaaaataaa ctttgatggt agaattcttg
     5641 ttgaacaaaa ccggagccag atattctatc acaccaaatt gggtaatagg aagctcacct
     5701 tcgtaaagtt tctttttacc gtcggtcagt gtaaccatag cttgtccggg tacgttgtag
     5761 gcgattccat ccaaatcttt cttcttctta ccatcttcct gtggcatctt gaccgatttc
     5821 aggtctttca gactgatata aaacggagtt cctgccaaat cattgttggc aactacacct
     5881 aacttcttcg agaagcggaa agcaacttca ttgttgaatt ccttgtcagg ggtaaggcgg
     5941 acagtgaatg ttctctcttc tttgttgcag gtgccggaga acatttgcgt catggcttct
     6001 tcctgtgcat tcagattgtc gagcataatc ttaagctgtg ctccgtctga aggcatattg
     6061 tcagcctgtc cgcgcaataa ggcatttttg ctttcgcgga tgttatagat ttctttagcc
     6121 accagctcgg ccatcttggc ggtagagcta gccatcagaa tctcttcggt caggaattcg
     6181 cgaggattcg ctttcttttg gaggactgcg ggggcgggag cagctttttt gcctacactg
     6241 ctattgctgt aaggaacatt gatcgttttc acaatgccat cctctgtcag ttccataagc
     6301 ggtgctactg tcttatcctt caattttacg aaatacgtag tttcgctgtt gggcacacct
     6361 acggatttca cttttacgct agccagttcc cagtactctt caggatcggc ggagacgttg
     6421 gtcagtcgca ggtaacgatc agcatatttg ctgaattctc ccggagtata gttgactttg
     6481 ttggctttta tttcaagttc tatttgggtt ttgggaagac tgtaaaccac tccatagtct
     6541 tttcctcggg taacccctgt cagtacttcg gtttgtgcat aggcggacgt tgtcattagt
     6601 agtcctgctg ctataatcaa ctttttcata ttcggttctt ttttaactgg ttttgaaaac
     6661 aaagttaatg aagttattga aaaaagggta agttcttaac ttttattcgc ttacaagttg
     6721 ccatgctgtc ggcagacagg tgataatatc gcttgcgatc attccgatca ttccttgctt
     6781 cttttgagcg acatcgcccg ccaatccgtg aatgtaagtg ccgattttag cggcttcttc
     6841 ggttgagtaa ccttgggcaa gcagtgccag gattactccg gtcagtacgt caccgctacc
     6901 tccggttgcc attcccggat ttccggttgg gttgaagaaa catttacctt ctggggtgat
     6961 aatggcggag taggctcctt ttaaaataat gtgaacatgg gcggcacgag ccaattcgca
     7021 agccttcatc agacgttcgt aagagtcctg gcatttgccg gtcagacgtt ccagttcttt
     7081 cggatgcggg gtgaggatgg aacccttcgg caggtgggta agtgcatgac ggtggttggc
     7141 gaggatatta agtgcgtcgg catccaccac aacaggagtc tggcaatgtt ccagttgctc
     7201 caataaagca gcttccgttt cctcgtttcg tcccagccct gggccgatgc cgactgcttg
     7261 atagtcgtcc gtgtcggtag gtacggcaaa acaggtttcg ttgatgtcgg tttctacgat
     7321 tgcttcgggt atggaggttt gcaagatgtc gttgttgcac attggcgcat ggacagtcag
     7381 caaccctact cccgaacgga ggcaggcgcg ggcagcgaga acagaggctc ctgccattcc
     7441 ttttgaaccg gcaatcaata gtgcatggcc gaagttcccc ttgtgggcaa actgtttgcg
     7501 tggcttgatg agtgaacgga tttgctctat ttccaacatt tcgtagttcg tttccatctc
     7561 ttcaataccg tcttcgctta attggatgtc cagcacttcc cattctccga caaattccgt
     7621 gttctctgcg aaaagaaagg cgagcttcgg cagttgcaga ctgaaagtta cgtcggcacg
     7681 gataatatta gcttttacgt tgaatgtgtt ttcttctccc atcagtccgg aaggaatgtc
     7741 gatggctact accatagcag gggaggaatt gatgtatttc actacggcag cgaatccgcc
     7801 gcttaacggt ttgttcaggc ctgaaccgaa taatccgtcg attaccagat ggtcgggcgt
     7861 caggacggga ggtacgaatt gggtactgat ttcgtggaat tttacttctt ccatcatttc
     7921 taccagttct ttattggttt ggcagtcggg tgaaagttct cctttcgtgt tgaagagaaa
     7981 tacctcgatt ttatatcctt tttcagccat catgcgggct acggcgagag cgtctccgcc
     8041 attattcccc ggtccggcaa agatagtgac cggcgtttcc gtattccatc tgtctgtgat
     8101 ggcttttgtt aatacggttg ctgcacgttc catcagatcg attgatgcaa taggttcgtt
     8161 ctcaatggta taagcgtcca atttcttgat actgctgctt ggaaatattt tcattgcgat
     8221 gttcttttag ttttcggatt acaaatgtac atgattcttc tgacttttcc cgtttgttgt
     8281 gggaagaaaa ccataattgc aacttttaat tcatcattag ttctatcttt gggtcagaga
     8341 aatatctgct tttgaactat taagtgttag aataactccg ccaaaaaata attcaatgca
     8401 gcaccattat gaacttactt ttatttctcc tgaaaaagat ttcttcattt catttctcat
     8461 attctcattg tttttcgata aacgaaagct aatcaaatag atatcttatg agaaacactt
     8521 tttcgaaacg gtatttctca taagttctcc catattttgg ctcaaaagcc accttattct
     8581 catagtattt cagggtattt ctcatagtca aaagccattt gttcttcctt ttttctttca
     8641 gcctgcctta tttttatcag gaaatgaagc tactatttag ataaaatagt ggctttttgc
     8701 ttgaagatgc tcattggtct cgattgtccc atatattgtg ggaaagtttt ccttcaatat
     8761 acgggaatac tttcctacaa aatacgggaa tactttccca agccttaggg aatcttttcc
     8821 cacaatatgt ggaactaaga cactgtgtat ggaagcaagc aaaaggaata catagtttta
     8881 tttattcaat gtcagcttcc ggcacactac actatgagaa atgaagcaaa atccgggtta
     8941 ttttgcgaag aaactatgag aaatgcctgt ttttaaatca tttctcatag tctatcttat
     9001 tagtttactg ccacttgttt cttatttatg agaatatgag aaatgaaaaa tctttttctg
     9061 tagaggcgcg gatgaaaatt gtgtttagtt tatcgccata ccttcttaaa caaattttta
     9121 atgcggttcc ccttattaag cctttgatta tttgccgttt ccgataaaaa tgttatcttt
     9181 ggagatagat aatgtgcatc acatcatttt ccagtgctca caatgaaaat gaattaaaat
     9241 ctaaataacg gattgtttaa tcttctaaag tttgcatgat ggaaaagaca aaaattggct
     9301 tgaatgccgg gaaagtatgg cgcatcttaa atgaaaaagg tgaactttca atgttcgatt
     9361 tgtgccgtga attaagtttg acgtttgaag acgtagctct cgctattggt tggctggccc
     9421 gagaagacaa aatctttttg aggaaaagag aaggaatgct ttttgccagt atcgaaaatg
     9481 tcgaatttac ttttggctaa ggtggtagct aacctacatt taagatggat ctccacttta
     9541 ttatttacac tgctaaaaaa gtaatgaagt ggatcagtag gatttttatg ctcgttttta
     9601 ctattccccc tattattctg tttgataaga gaagcatcta atctactttt tctgtacctt
     9661 tgcaccccat aaactactaa acacataaat tcatgagtgc attgaaaggg catccgaaag
     9721 gcctttatct gattttcgcg acaagcacgg cagaacgttt cagttactac ggtatgcgtg
     9781 cgatctttat tcttttcctg acgcaggcat tattgtttga caaagaagcg gcagcatcca
     9841 tctacggcag ctataccgga ctagtttatt taaccccgtt gattggcgga tacattgccg
     9901 ataaatattg gggaatccgt cgttccgtgt tttggggagc ggtaatgatg gcagtcggac
     9961 aattcctgat gtttatgagt gcctccactt tagataatac gaaccttgcc cactggatga
    10021 tgtatggtgg actcggcttc ctgattctag gcaatggttg cttcaaaccc actgtctctt
    10081 ctctggtagg tcagctctac gaacccggag acaggcggtt ggatgctgca tacaccattt
    10141 tttatatggg agtgaatgta ggctcttttg ctgctccttt gatttgtggt tatctgggtg
    10201 ataccggtga tccgcatgac tttaaatggg gatttcttgc agccggaatc atgacactgt
    10261 tcaccgttgt tcttttcgag actcaaaaga ataaatatct tttttctcct tccggagaac
    10321 cgattggtat tatccccgat gctaaacgtg aaaagaaaga agacaaggcc gaccatatct
    10381 cacacccgaa gatggacaaa cgtaccaaag tacgtaatac ccttgtaatc acaattctta
    10441 ccattgcttt aatagccttc tttaactatg catttgaagg cgattgggtg agtatcggca
    10501 tttttaccgc ctgcattgtt ttccctgttc tgatcctgtt agacggttca ttgacaaaaa
    10561 tagaacgcag ccgtattttc gttatctata tagtagcctt ctttgtcatc ttcttctggg
    10621 cagcctacga acaggcggga gcttctttaa ctctcttcgc atccgaacag acgaatcgtg
    10681 acatattcgg ttgggaaatg ccggcttcat ggtttcaatc cttcaatcca ctgtttgtag
    10741 ttgtcctggc atatatcatg ccgggtgtat gggggttcct gaacaagcga aagatggaac
    10801 ctgcttctcc taccaaacaa gcgattggtc tgttactcct ttctttaggt tatcttttca
    10861 tctgtttcgg agtgaaagat gcagttcccg gagtgaaagt gagcatgatt tggctgacag
    10921 gactttactt tattcatacc atgggtgaaa tagctttgtc gcctatcgga ctttcaatgg
    10981 taaataaatt gagtccgctg cgtttcgctt ccctgatgat gggaatctgg tatctgtcta
    11041 ctgccacagc caataaattt gcgggaatgt tgagcggact ctatccggaa gccggaaaag
    11101 tgaagtcaat ctttggttat cagattgcta ccatgtatga tttctttatg gtattcgtcg
    11161 taatgtccgg tgttgcttcg ttgattctgt tccttctctc gaagaaatta cagaagatga
    11221 tgcacggggt agaataaaaa atcgtatttt tgcaaggtta tttttaaatt accggttatg
    11281 gataccattc agataaaaga caaattgttt accgtttcca ttaaggaaca agaaattcag
    11341 aaagaagtga ttcgcgtagc gaacgaaatc aaccgcgatt tggcaggtaa gaatccgctt
    11401 ttccttagtg tgttgaacgg ttcgttcatg tttactgctg atttactgaa gcacatcacc
    11461 atcccttgtg aaatctcatt tgtgaagttg gcgtcttatc agggcatcac ttccaccgga
    11521 gtgattaaag aggtaatcgg cctgaatgaa gacattgccg gacgtaccat tgtgatcgta
    11581 gaagatatcg tagacacagg actgacgatg cagcgactgc tcgaaacatt aggtacacgc
    11641 aatcccgaag ctattcatat cgcttctctg ttggtgaaac ctgaaaagct caaggtaaac
    11701 ctcaacattg aatatgtagc gatggaaatc ccgaacgact ttatcgtagg ttacggactg
    11761 gattatgatg gtttcggacg taattatccc gatatttata cagtagtaga ttaatattaa
    11821 ataggtacca gtttaaatgg taaatagtaa atcgttaaat tgtaaataac aaaatgttga
    11881 acatcgtaat tttcggtgct ccgggttcag gaaaaggaac acagagcgaa cgtatcgtag
    11941 aaaagtatgg aatcaatcac atctcgacag gagatgtatt gcgtgctgaa atcaagaatg
    12001 gcacagaact gggtaaaaca gctaaaggtt atatcgacca aggtcaattg attcctgatg
    12061 aattaatgat tgatattctg gcaagcgtat tcgacagctt caaagatagc aaaggggtaa
    12121 ttttcgacgg tttcccaaga acaattgcac aagcagaagc attaaagaaa atgttggcag
    12181 aaagaggaca ggacgtttct gtaatggttg acttggatgt tccggaagaa gaactgatgg
    12241 tacgtctcat taaacgtggc aaggattccg gtcgtgctga tgataacgaa gaaacaatca
    12301 agaaacgtct gcatgtatat cattcacaga ctgctccact gatcgactgg tacaagaacg
    12361 aaaagaaata ccaacacatc aacggcttgg gtactatgga aggtatcttc gctgaaatct
    12421 gcgaagcagt agataaattg taataataca atattataaa taaataagtc agtagccgga
    12481 gtgttctaat taactgctct aactactgac tactttaact ctttaaaaaa atatggctga
    12541 atcgaatttt gttgattacg taaagatata ctgtcgctcg ggcaagggcg gaagaggctc
    12601 tacgcacatg aggcgcgaga aatattgtcc taacggaggt cctgatgggg gcgatggtgg
    12661 aagaggaggt catatcatct tgcgcggtaa ccgtaattac tggacattgc tgcacttgaa
    12721 gtatgaccgt cacgcaatgg ccgggcatgg tgaatcgggg agcaaaggac gtagcttcgg
    12781 aaaagacggt gcggataaaa taatagaagt accctgcgga acggtagttt ataatgccga
    12841 gacaggggag tatctttgtg acgtaacaga agacggacag gaagtggtct tgctcaaagg
    12901 cggccgcggc ggtcagggta actggcattt caagacggcc acccgtcagg ctccgcgttt
    12961 tgcgcagccg ggagagccga tgcaggaaat gaccgttatc atggagctga aactgcttgc
    13021 cgatgtcggt ctggtaggtt tcccgaatgc gggaaagtca actttgcttt cttccatttc
    13081 ggctgccaaa ccgaaaattg ccgattaccc gtttactacg ctcgaaccca acttgggcat
    13141 cgtttcctat cacggtggaa aatcctttgt gatggcggac ataccaggta ttatcgaagg
    13201 tgccagtcag ggaaaaggtt tgggactgcg tttcttgcgt catatcgagc gtaattcatt
    13261 actgctgttt atggttccgg cagacagcga cgacattcgt aaagaatacg aagttttgct
    13321 gaacgaactg cgtaccttca atcctgaaat gttggacaag caacgtgtgt tggctgtcac
    13381 caaaagtgat atgctcgatc aggagttgat ggacgagatt gaacctacat tgccggaagg
    13441 cattccacat gtattcatat cttctgtttc cggtttgggc atctcggtgt tgaaagacat
    13501 cctttgggaa gaactgaaca aggaaagcaa taagatagag gacatcgttc accgtccgaa
    13561 agacgtgacc cgtctgcaac aggaactcaa agacatgggc gaagatgaag acatcgttta
    13621 tgaatatgag gaagatgtcg acgatgacga tgatatcgat tatgaatacg aagaagaaga
    13681 ttgggaagaa aaatgatttc acttacaaaa cataacgagt tgaagggata taagtcactg
    13741 gaggcatatc ccgaagtagc tcattttgta actacgcgtc acgaaggtat aagcaccgga
    13801 gcttacggct ctttcaactg ttcgccttat accaacgact catgtatgaa tgtcaatcgc
    13861 aatcagagct ggttgtttca gtgcatgaat catcagataa aggaattatt tattcctgaa
    13921 cagaatcatg gctgtgccag tctgattatc aatgaatcat tttttaaaga atcattggaa
    13981 atgagacggc tacttctgcg aggaatggat gccttgataa ctaatgtgcc gggatattgc
    14041 gtttgtgtca cgacagcgga ttgtgttcct gtattgctgt acgacaaaaa acaacacgtt
    14101 gtggctgccg ttcatgccgg atggaaggga acggtgaagc atattgtcag tcatgtgatg
    14161 gaccacttga ataagatgtt cgggacgcaa ggcgaagatg tgatagcttg catcgggccg
    14221 agcatttcgc tcgaatcatt tgaagtaggt gatgaggtgt atgatgcttt tgaagaaagc
    14281 ggcttcgata tgtctcttat ttctatgaag aagaaagaaa caggcaaata tcatattgat
    14341 ttgtgggaag ccaaccggat tgaattactg aatctcggag tgcctgcaga acagatagaa
    14401 gtggccggaa tctgtaccta tattcatcat gatgaattct tctctgcacg tagactggga
    14461 atagattccg gtcgtacatt gtcgggaata atgattagaa agtaataatt ggtgtccgtt
    14521 attgcaggac gctgatgatt ggtttatgat aagttatgtt tgaaataaaa gtatctaaag
    14581 aaataaaaga cgcatgcccg gtttttgccg gagccgccgt gtatgctgca gtgaaaaata
    14641 cagcttacag cgaagggctt tggcaggaaa ttaacgcttt taccgggcaa ctgacttcca
    14701 caacacagat ggaagacatc aaacatcaac ccgttatctt tgctacccgt gaggcttata
    14761 aacgttgtgg caaagacccc ggacgttacc gcccgtcagc cgaagctcta cgccgccgcc
    14821 tgatgcgtgg aattccttta tatcagattg atacgttggt agaccttatt aatttagtgt
    14881 ctcttcgcac aggacattcg atcggtggtt ttgacgcgga caaaatacaa ggtacgcatc
    14941 ttgaactcgg tatcggcaaa gcaggagaac cgtttgaagg tatcggacgc ggtgtattga
    15001 atatcgaagg attacctgta tatcgtgatt ctttcggcgg aatcggaacc ccgacaagcg
    15061 accatgaacg tacgaagatg gacctcgaaa ctactcatat cctagccata gtcaacggtt
    15121 ataacggaaa agaaggtttg cgagaagctg ctgaaatgat acagacctta ttaagaaact
    15181 atacagaatc ggatggaggc gaaatcgtat tcttcgaata a
//
