LOCUS       gnlProkkaCGPCKGDH_268   3682 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CGPCKGDH_268.
ACCESSION   gnlProkkaCGPCKGDH_268
VERSION     gnlProkkaCGPCKGDH_268
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 04:16:21
            Original ID  :: gnl|Prokka|CGPCKGDH_268
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3682
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3682
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[2:2802]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..2802
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..3682
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3682
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             3..1217
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (15-197). E-value:
                     1.7e-22. Score: 71.8. Matches aSDomain:
                     nrpspksdomains_ctg268_1_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 135.1; E-value:
                     5.7e-41)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg268_1"
                     /sec_met_domain="APE_KS2 (E-value: 2.1e-73, bitscore:
                     235.6, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFITSGFLSFRSVSAHRCRPYDIQRDGLSLGEACGAVLLETQGNA
                     NHIILSGGAISNDANHISGPSRTGDGLALAINQAMEEAGALPEDISFINAHGTATVYND
                     EMESKAIHLAGLSAVPVNSLKPYFGHTLGASGIIETILCIEQLKEGIYYGTLGYETLGV
                     PMPIIVYSTHQPMPMKCCIKTASGFGGCNAALVLSLPDAHLKQKTDSLASCKAAVESAN
                     TVTIKPGVVENQGTAIFNSSETDFAPFIREAYKHLGENNMKFYKMDNLCKLGYVAAGYL
                     LKDTNYRPEEIGIILANASASLDTDCRHQAIINKEGDKAASPAVFVYTLPNVVLGEICI
                     RHKIQGENTFFVCQQSDTASLEDYARIVMAKGKLRTCIIGWCELLDGHYQAEFKQLNNI
                     STIYE"
     aSDomain        48..593
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg268_1_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.70E-22"
                     /label="ctg268_1_PKS_KS.1"
                     /locus_tag="ctg268_1"
                     /protein_end="197"
                     /protein_start="15"
                     /score="71.8"
                     /tool="antismash"
                     /translation="HRCRPYDIQRDGLSLGEACGAVLLETQGNANHIILSGGAISNDAN
                     HISGPSRTGDGLALAINQAMEEAGALPEDISFINAHGTATVYNDEMESKAIHLAGLSAV
                     PVNSLKPYFGHTLGASGIIETILCIEQLKEGIYYGTLGYETLGVPMPIIVYSTHQPMPM
                     KCCIKTASGFGGCNAALVL"
     CDS             1210..1491
                     /NRPS_PKS="Domain: PP-binding (22-68). E-value: 5.7e-11.
                     Score: 34.7. Matches aSDomain:
                     nrpspksdomains_ctg268_2_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg268_2"
                     /sec_met_domain="PP-binding (E-value: 4.1e-12, bitscore:
                     34.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLDQTKRELMDEVKGKLIEELNLEEITPEDIDDEAPLFGDEGL
                     GLDSIDALEIILILEREYGIKIENPSEGKQIFYSVCTLTDYIIANRKA"
     aSDomain        1276..1413
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg268_2_PP-binding.1"
                     /evalue="5.70E-11"
                     /label="ctg268_2_PP-binding.1"
                     /locus_tag="ctg268_2"
                     /protein_end="68"
                     /protein_start="22"
                     /score="34.7"
                     /tool="antismash"
                     /translation="LNLEEITPEDIDDEAPLFGDEGLGLDSIDALEIILILEREYGIKI
                     E"
     CDS             1495..2802
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (152-423). E-value:
                     1.2e-38. Score: 125.0. Matches aSDomain:
                     nrpspksdomains_ctg268_3_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 253.5; E-value:
                     6.3e-77)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg268_3"
                     /sec_met_domain="APE_KS2 (E-value: 9.7e-114, bitscore:
                     368.4, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIYVTGLGVVSGIGIGVSENIEALQQGKHGIGKVTLFPTALDVP
                     VSEVKRSNEELKQLLSLPPQRTVSRTALLGMIAAKEAMEDAGLNLRISSNQPKNQLPNQ
                     SVTSQKDQQPLRIGFISATSVGGMDLSERFYESFKKNPKQGRLREVISHDCGASTELIA
                     SYLGINDFITTISTACSSAANAIMLGARLIKHGQLNAVIVGGTDALCRFTLNGFNSLMI
                     LDKIHCRPFDRSRSGLNLGEGAGYLVLQSESSLQRVPYCELSGYANTNEAYHQTGSSPE
                     GDGAFLSMSEAIASSGISPEDIDYINVHGTGTPGNDASEGMALRRIFGEHVPPFSSVKA
                     FIGHTLGASEGIEAVYSVLSIDKGMIYPNLNFTEPMPETELLSETGVKSETGLIPETSF
                     QEGVPIRHVLSNSFGFGGNDSSLLFSATNFPKRTNL"
     aSDomain        1951..2763
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg268_3_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.20E-38"
                     /label="ctg268_3_PKS_KS.1"
                     /locus_tag="ctg268_3"
                     /protein_end="423"
                     /protein_start="152"
                     /score="125.0"
                     /tool="antismash"
                     /translation="HDCGASTELIASYLGINDFITTISTACSSAANAIMLGARLIKHGQ
                     LNAVIVGGTDALCRFTLNGFNSLMILDKIHCRPFDRSRSGLNLGEGAGYLVLQSESSLQ
                     RVPYCELSGYANTNEAYHQTGSSPEGDGAFLSMSEAIASSGISPEDIDYINVHGTGTPG
                     NDASEGMALRRIFGEHVPPFSSVKAFIGHTLGASEGIEAVYSVLSIDKGMIYPNLNFTE
                     PMPETELLSETGVKSETGLIPETSFQEGVPIRHVLSNSFGFGGNDSSLL"
     CDS             2815..3681
                     /locus_tag="ctg268_4"
                     /transl_table=11
                     /translation="MQPVYIQRIASIHPQGNHSQENNPKVNDSLDVAANRPFLQACEPD
                     YKDIIANATLRRRMSRIVKMGVACGLECMGELSPEKIGGIITATGLGCLVDTEKFLNNL
                     LDNEERMLNPTPFIQSTFNTIGAQIALIHQIHAYNMTYVHRGLSFESALLDAMMKIEEG
                     SENILVGAMDEMTETSYIIQQRLGLLKGIEAGEGAQFFLLSREAGEHPLAEIRGLETFT
                     GQHTTEEISSRIIRFLQRNGLECQGIQWLVTGKNKKQSLQGDYHEQITGYKKSTINEGK
                     STNQRSII"
ORIGIN
        1 ctcattttat taccagcggt ttcttgtctt tccggtcagt cagcgcacac cgatgccggc
       61 catacgatat acaacgggac ggattaagtc taggcgaagc ctgtggagct gtgcttttag
      121 aaactcaagg aaacgcaaat catattattc tatccggagg agcgatcagc aatgatgcca
      181 accatatatc cggtccttcc cggacaggag acggactggc gctggctatc aatcaggcaa
      241 tggaagaagc cggagcactt cctgaagata tcagctttat caatgcacac ggaacagcta
      301 cggtttataa tgacgaaatg gaatccaaag ccatacattt ggcaggattg tctgcagttc
      361 cggtaaatag tcttaagcct tatttcgggc atacattagg agcttcaggc attattgaaa
      421 ccatactttg catagagcaa ctaaaagaag gaatatacta cggaacttta ggatatgaga
      481 cactgggtgt tcccatgcct atcatcgttt atagcactca tcagccgatg ccaatgaaat
      541 gctgtatcaa aaccgcttcc ggtttcggag gctgtaatgc tgcactggta ttatctctcc
      601 cagatgctca tttgaaacag aaaactgatt ctttggcatc ctgtaaagct gccgtagaat
      661 cagccaatac agtcacgatc aaaccgggag tggtagaaaa ccaaggaaca gctatattca
      721 attcttcgga gactgacttt gcgccgttta tccgggaagc atacaagcat ctgggagaaa
      781 acaatatgaa gttctacaag atggataatc tttgtaagct tggatatgta gctgccggat
      841 atttattgaa agataccaac taccgtccag aagagattgg aatcattcta gccaatgctt
      901 ccgcctcttt ggatacggac tgcagacatc aagctatcat caataaagaa ggagacaaag
      961 ccgccagtcc tgccgtattt gtctacactc tccccaatgt agtattggga gaaatctgta
     1021 tacgacacaa aattcaggga gaaaatacat tctttgtctg tcagcaatcc gacactgctt
     1081 ccttagagga ttacgcaaga attgtgatgg cgaaaggtaa gttacgcaca tgcatcatag
     1141 gctggtgcga actactggac ggacattatc aagcagaatt taaacaactt aataatatat
     1201 caacgattta tgaataattt agatcaaacc aaaagagaac tgatggacga agtgaaaggt
     1261 aaactaatcg aagagttgaa ccttgaagaa atcactccgg aagatattga cgatgaagcc
     1321 cctctgtttg gcgacgaagg tcttggcctt gactccattg acgcactcga aatcatcctg
     1381 attttggaac gtgaatatgg cattaaaata gagaatccta gtgaaggaaa acaaatcttc
     1441 tactcggtat gtacactgac tgactacatc attgctaatc ggaaagctta acttatgaag
     1501 atttacgtca ccggattggg agttgtttcg ggcatcggca tcggagtttc cgaaaatata
     1561 gaggcactac aacaaggaaa gcatggtatc ggaaaggtaa ctcttttccc gactgctctc
     1621 gatgtacccg tatctgaagt gaaacgtagc aatgaagaac ttaaacaact attatcttta
     1681 cctccgcagc gtacagtatc acgcacagca ttgctaggca tgatagccgc caaagaagcg
     1741 atggaagatg caggactaaa cttgcgtata tcatccaatc agccaaaaaa tcaattacca
     1801 aatcagtcag taacctcgca aaaagaccag caaccgttac gtattggttt tatttccgcc
     1861 acctctgtcg gcggtatgga tttaagcgag cgtttctatg aatctttcaa gaaaaacccg
     1921 aaacagggac gattgcggga agtgatttca cacgactgcg gagccagtac cgaattaata
     1981 gcttcgtatt taggtatcaa tgattttata accaccatca gtacagcctg ttcatcggca
     2041 gccaatgcta ttatgttggg agcgagactg attaaacatg gacaactgaa tgctgttatc
     2101 gtcggaggta cggatgcact ttgccggttt acgctcaatg ggttcaactc tctcatgatt
     2161 ttggacaaaa tacattgtcg tccttttgac cgttcacgtt ccggattaaa tttgggagaa
     2221 ggcgcgggtt atttagtgct tcaatcagaa agttcactcc aaagagttcc ttactgtgaa
     2281 ctaagcggtt atgctaatac aaatgaagct tatcatcaaa caggaagttc tcccgaagga
     2341 gatggcgcct ttctatcaat gagtgaagcc atcgcttcca gtggcatttc tcctgaagat
     2401 attgattata tcaacgtaca tgggacaggt actcccggta atgacgcatc ggaaggaatg
     2461 gcactacgaa gaatcttcgg agaacatgtt ccaccgttta gttcggtaaa agcttttatc
     2521 ggacacactt taggagcttc cgaaggaatt gaagctgttt attccgttct ttccatagat
     2581 aaaggcatga tttatccgaa tctgaatttc acggagccta tgccggaaac agaactgttg
     2641 tcagaaacag gagtaaaatc agaaacagga ttgataccgg aaacatcttt ccaggaagga
     2701 gtgccgatcc gccatgtatt atccaattct ttcggcttcg gaggaaacga ctcgtcgctc
     2761 ctcttttccg caacgaattt tcccaaacga acgaaccttt aagtttttga gcctatgcag
     2821 ccagtttata ttcaacgcat cgcttctatc catccacaag gaaatcattc acaagaaaat
     2881 aatccgaaag taaatgattc gctcgatgtt gcagcaaacc gtccttttct tcaggcttgt
     2941 gaacccgatt ataaggatat tattgccaat gcaactttgc gcaggcgcat gagccgtatt
     3001 gtgaaaatgg gagtggcttg cggattggaa tgtatgggcg aactatctcc cgagaagata
     3061 gggggaatta tcacagccac agggctgggc tgcctggttg atacggaaaa gtttctgaac
     3121 aacctgttag ataatgaaga gcggatgctg aatcctactc cttttattca gtcgacattc
     3181 aatacaattg gtgcacaaat agcactgatt catcaaatac atgcctataa catgacttat
     3241 gttcaccggg gactaagttt tgaaagcgct ttgctggatg ccatgatgaa aatagaagaa
     3301 ggaagcgaga atatactggt gggagccatg gacgaaatga cagaaaccag ttacatcatt
     3361 cagcaacgct tgggactgct gaaaggaata gaagccggag aaggcgctca attcttccta
     3421 ttaagccggg aagccggaga gcatccgtta gcagaaatac gaggacttga aactttcacg
     3481 ggacaacata cgacagaaga aatcagttcc cgaattattc gttttttaca acgaaacgga
     3541 ttagagtgtc agggtattca atggttagtt accggaaaga acaaaaaaca atcccttcaa
     3601 ggtgattacc acgagcaaat cactggttat aagaagagta ctataaatga agggaaaagt
     3661 acgaatcaga gaagtattat aa
//
