LOCUS       gnlProkkaNKHGFJOM_677  15238 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NKHGFJOM_677.
ACCESSION   gnlProkkaNKHGFJOM_677
VERSION     gnlProkkaNKHGFJOM_677
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 00:08:58
            Original ID  :: gnl|Prokka|NKHGFJOM_677
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15238
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15238
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4863:5238]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4864..5238
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15238
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15238
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..182
                     /locus_tag="ctg677_1"
                     /transl_table=11
                     /translation="MAGKGVACEDSFRQAIYVAIDVFRNRQREKVARANPLRKQYYEKR
                     DDSDKLKLDTVDED"
     CDS             192..1433
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg677_2"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             1420..1947
                     /locus_tag="ctg677_3"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             1953..2726
                     /locus_tag="ctg677_4"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQSAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             2733..3128
                     /locus_tag="ctg677_5"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             3378..4766
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg677_6"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             4864..5238
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg677_7"
                     /sec_met_domain="PqqD_RRE (E-value: 1.8e-11, bitscore:
                     34.1, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6.6e-18, bitscore: 55.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVVYRNLLLFI"
     CDS             complement(5231..5515)
                     /locus_tag="ctg677_8"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(5552..6619)
                     /locus_tag="ctg677_9"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKMPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             complement(6692..8203)
                     /locus_tag="ctg677_10"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             complement(8478..8594)
                     /locus_tag="ctg677_11"
                     /transl_table=11
                     /translation="MRNTLKYYENKVAFEPKYGRTYEKYRFEKVFLIRYLFD"
     CDS             9265..9489
                     /locus_tag="ctg677_12"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             9682..11226
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 46.8; E-value: 2.5e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg677_13"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASTLDNTN
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKADHISHPKMDKRTKVRNTLVITILTIALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDIFGWEMPASW
                     FQSFNPLFVVVLAYIMPGVWGFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAVP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             11267..11803
                     /locus_tag="ctg677_14"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             11863..12432
                     /locus_tag="ctg677_15"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             12522..13685
                     /locus_tag="ctg677_16"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAET
                     GEYLCDVTEDGQEVILLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     VTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEDIVYEYEEDVDDDDDIDYEYEEEDWEEK"
     CDS             13682..14494
                     /locus_tag="ctg677_17"
                     /transl_table=11
                     /translation="MISLTKHNELKGYKSLEAYPEVAHFVTTRHEGISTGAYGSFNCSP
                     YTNDSCMNVNRNQSWLFQCMNHQIKELFIPEQNHGCASLIINESFFKESLEMRRLLLRG
                     MDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSNVMDHLNKMF
                     GTQGEDVIACIGPSISLESFEVGDEVYDAFEESGFDMSLISMKKKETGKYHIDLWEANR
                     IELLNLGVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRTLSGIMIRK"
     CDS             14545..15210
                     /locus_tag="ctg677_18"
                     /transl_table=11
                     /translation="MFEIKVSKEIKDACPVFAGAAVYAAVKNTAYNEGLWQEIDAFTRQ
                     LTSTTQMEDIKHQPVIFATREAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDL
                     INLVSLRTGHSIGGFDADKIQGTHLELGIGKAGEPFEGIGRDVLNIEGLPVYRDSFGGI
                     GTPTSDHERTKMDLETTHILAIVNGYNGKEGLREAAEMIQTLLRNYTESDGGEIVFFE"
ORIGIN
        1 atattgcagg caagggagtg gcttgtgaag attctttccg ccaggcaatc tatgttgcca
       61 tcgacgtgtt ccgtaatcgt cagcgtgaaa aagtggctcg tgccaatccg ttgcgtaaac
      121 agtattacga gaaacgtgac gatagtgata aactgaagct ggatacagta gacgaagatt
      181 aaaaacgagt gatgacgaaa gcagagatac aacaagtgaa acagcgtttc ggtattattg
      241 gaaatactga agcattgtcg cgcgccatag atgttgccat tcaggtagct cctaccgatt
      301 tgtctgtgct gattaccgga gaaagtggag tcggaaaaga aagttttccg cagattattc
      361 atcaatatag ccggaggaag cacggacagt atattgctgt caactgtggc gctattccgg
      421 aaggtacgat tgattccgaa ctgttcggac atgagaaagg tgcgtttacc ggtgcgattg
      481 gcgaacggaa agggtacttt ggcgaagccg acggcggtac tatttttctt gatgaagtag
      541 gggagttgcc gatgtctacc caggcacgtt tgctccgtgt actggagagt ggcgagttta
      601 tgaaagtagg ttcgtccaaa gtacaaaaaa cggatgtgcg tgtggtggcg gctaccaatg
      661 tcaatctgac acaagcgatt gcagaaggac gtttccgtga agatttatat taccggttga
      721 atacggtgcc tatccaaata ccgcctttgc gtgaacgtgg tgacgatgta cttttgttgt
      781 tccgtaagtt ttccgcagac tttgcagaga aataccggat gcctgctatt cagttgacgg
      841 aggatgcgaa gaaagagttg ttggcttacc cgtggcccgg aaacgtgcgc cagttgaaga
      901 acatcaccga gcaaatatct atcattgaaa ccaacaggga gatctctgct gctatcttgc
      961 agaattatct tcccgcacaa aatacgcaac gtcttcccgc gctgatggga acgcgtgaga
     1021 gtaaaggctt tgagagcgaa cgggagattc tttattctgt tctgttcgat atgcgccagg
     1081 aagtggcgga gctgaagaag atggtgcaca acctgatggc ggaacgtgcc ggacaggtgg
     1141 ggcaggtagg acaaatggga acggtggtta ctactccggt agtgacggcg catcaacctt
     1201 cggtacctgc tattattcac accatgcagc ccacggtttg caaggatgat gatgacatac
     1261 aagacacgga agaatatgta gaagaatctc ctttgtcact ggacgaagtg gagaaagaaa
     1321 tgatacgcaa agcacttgag aggcatcatg gaaagcggaa gagtgcggcc aaggacttga
     1381 atatttccga gcgtacactt tatagaaaaa taaaagaata tgaattggat taagaaaata
     1441 atacgccctt tgttactgtt cggcttgccg ttggtagtca ttgcgtgcac tgtttcctat
     1501 aagtttaacg gatcgtctat caattatgat aaggtaaaga ccatttcgat agccgacttc
     1561 ccgatcaagt cggagtatgt gtatgctccg ttggcaacca agttcaatga ggacctgaaa
     1621 gatatcttca tccggcagac tcgtctgcaa ctgctcaagc cgagtcaaaa tgccgacttg
     1681 cagattgacg gagaaatcac agggtacaat cagtacaatc aggcagtatc tgccgacggt
     1741 tattcttcgg agacgaagtt gactatcacc gtcaatgtac gttttgtcaa caacaccaat
     1801 catgccgaag actttgaaca acagttttct gcgttccgta cctacgactc tacccagttg
     1861 ctgactgctg tacaggacgg attgattgct gaaatgtcta aagagatcac cgaccaaatt
     1921 tttaatgcaa ctgtagcaaa ctggtaatat aaatgacttc tgttaacttt caacaatgga
     1981 ttcagcatcc cgagacgctg aatagggata ctttgtacga actgcgcaat cttcttgcga
     2041 ggtatccgta ttttcagtca cttcgtctgc tgtatctgaa gaatctgtat attctccatg
     2101 atattagttt tggtggagaa ctgcggaaag cagttcttta cattgcagac agacggcagt
     2161 tgttccggtt gattgaaggt gaccgctatg atgtgcaggc acggaaaaag ggagtacctc
     2221 ttacggaggt actgaaagac gaaccgtccg tagaccgcac attagcattg atcgacgctt
     2281 tcttgtccac agtacccgaa gaggtgactg cccgcaccag cttcgactat tcgatggatt
     2341 acacctctta tcttttggag gagactccgg ccacggaaca gtcggccgaa gaaacgccca
     2401 aactcaaagg ctacgaactg attgacgact ttatagaaaa gagcgagagc gactctcccc
     2461 tctgcaagaa acctttaaga gaagaaatgc catcttcgcc aacctcttcg gacgaactta
     2521 ccgaagaaga aacgatgaag gaagaagagg aagatgacag ctgttttacg gaaactttgg
     2581 caaaaatcta tgttaaacag caacgatatt caaaagctct tgaaataatt aaaaaattaa
     2641 gcttgaaata tccaaaaaaa aatgcttact ttgcagacca aatcagattt ttggagaaat
     2701 tgattattaa cgctaattca aaataactaa aaatgtactt attattcgtt atcttaatgg
     2761 ttattgcagc cttgttgatg tgtttcatcg tgctgattca gaactcaaaa ggaggcggac
     2821 ttgcttctgg tttctcttca tctaacgcca tcatgggcgt gcgcaagact acagattttc
     2881 tggaaaaagc aacatggggc ttagctatct tcatggtggt aatgagcatt gctactgctt
     2941 atgtagttcc tcgctctgct gttgctaaag acgcagtgtt ggaacaggca cagaaagaac
     3001 aacagactaa cccgtataac ttacccgcag gtacggctgc gccgcaaact gaagctcctg
     3061 ctaccaatgc acctgctaca gaaactccgg caccggctac tgaaactcct gctcctgcag
     3121 cagagtaatt cactccgttg tcaggtaaga ctttggggta aaaccattaa tgggaaggtg
     3181 cagacggatg ctgcatttct ttgatattta agtgcggatt acgcagatta cacggatttt
     3241 caatcttccg cgtggtcagt gtaatccgca cttaactttt tcttgtaaaa acaatctctt
     3301 tttgatagaa acaaacgaga tttaactacc tttgttggtc gtatgaagat tattaactac
     3361 tatttttaaa tataacaatg acagaacatt tgaaacagaa attgaatgac tccgccgtac
     3421 tccgatggag tgttctagca ttagtcgcat ttactatgct atgcggctat ttcctcaccg
     3481 acgtaatgtc tcctctaaaa cccatgcttg agaaagaact actatgggac agtctggatt
     3541 atggtttctt cacaagcgct tacgggtggt ttaatgtatt cctattgatg ctgattttcg
     3601 gtggtatcat tttggataag atgggagttc gtttcaccgg aatgggagct tgcttattga
     3661 tggtgtttgg ttgtggattg aaatactatg cgatttctac tacttttccg gaaggtgcca
     3721 tgctcttcgg attcaaaaca caggtaaccc tggctgcatt ggggtatgct atcttcggtg
     3781 taggtgtgga aattgccggt atcacagttt ccaagattat cgtaaaatgg ttcaagggta
     3841 aggaaatggc attagctatg ggacttgaaa tggctacggc acgtatcgga acaactctgg
     3901 caatggtgct tacggttcct ttggccgact ttttcggatc tacggatgag agtggcacat
     3961 tccataccaa tattcctgct ccgattttgt tttgtctgat tatgttgtgc gtgggtacga
     4021 ttgctttctt cctttatact ttctatgata agaagttgga tgcttctttg gatgcagaag
     4081 gattggagcc ggaagagccg ttccgtatga aagatattgt gtatatcatt accaataaag
     4141 gattctggct gattgcatta ctatgtgtat tgttctactc ggctgtattc ccctttatca
     4201 agtatgctgc cgacttgatg gtgcagaagt ataatgtaga tccgaagttg gcgggaacga
     4261 ttcccggatt gttgccgatt ggtgcgatta tcctgactcc gttgttcggc tcgctttatg
     4321 accgtattgg taagggagcc acattgatga taatcggatc agtgatgctt atttttgtgc
     4381 atacgatgtt cgctctgcct atactgaata tatggtggtt tgctactatt atcatgatta
     4441 tattgggatt tgccttctcg ttggtgcctt cagctatgtg gccgtctgtt ccgaagatta
     4501 ttccggaaaa acagttgggt accgcatacg cattgatttt ctgggtacag aactggggat
     4561 tgatgggtgt tcctttgttg atcggatggg tgttgaatac ttattgcaaa ggtccggtag
     4621 tagatggtgc acagacttat gactacacgt tgccgatgac tatttttgct ctttttggtg
     4681 tgcttgctct gattgtggct ttgatgttga aggcagagaa caagaagaag ggatacggtt
     4741 tggaagaggc gaatatccaa aagtaactgg gaaattcaat acctaaagta acaaaggaat
     4801 tttgtatcaa ggtgtaaaca gaagagtatc agtataaata ctctgaaata aaaaataaga
     4861 agtatggctg ccaaagagaa aatcaacctg ttagaggtca ttccctgtcg cagtgaacat
     4921 attacagcag aaagggaagg ggagacaatt gtgctctcct ttccccgttt taaatatccg
     4981 tggatgcaac gcttccttgt gccgaaagga atgtcgaaag aacttcatgt gaaattggaa
     5041 gaacacggta cggctgtatg ggaactgata gatggaaaac gcaatgttcg tgagattata
     5101 gaaaaactcg cagaccactt tcaaaatgaa gagggctacg agtcgcgtgt atcggcttat
     5161 ctttctcaaa tgcagaaaga tggatttata aaactggtga taccagtcgt atataggaac
     5221 ttattattat ttatttgata aatacagccc aaagtatgac ggcaattgct atcaggaccc
     5281 ccatgataat aagcgttccc caaacaaaat aattgctgtc tttctctttc tttttctccg
     5341 agtcgtggat gatacgctcc atttcttcgg gagtggtgtt aggtagtgga taaggttcgt
     5401 ttgcacggtt tagatgcttc aacttatcgt tagcacgttc acgacgtagg cgggaagctt
     5461 cccgtccctc ttttattcgg cgtatcatgt cgaatgcatg tccttcacca accatattct
     5521 ttgtttttta gaagttcact tcctcgtttt tctatttccc ttcttctctg tccactttga
     5581 gcaatcctcc cgtattcgga tcaaaataaa ctttgatggt agaattcttg ttgaacaaaa
     5641 ccggagccag atattctatc acaccgaatt gggtaatagg aagctcacct tcgtaaagtt
     5701 tctttttacc gtcggtcagt gtaaccatag cttgtccggg gacgttgtag gcgattccat
     5761 ccaaatcttt cttcttctta ccgtcttcct gtggcatctt gaccgatttc aggtctttca
     5821 gactgatata aaacggagtt cctgccaaat cattgttggc aactacacct aacttcttcg
     5881 agaagcggaa agcaacttca ttgttgaatt ccttgtcagg ggtaaggcgg acagtgaatg
     5941 ttctttcttc tttgttgcag gtgccggaga acatttgtgt catggcttct tcctgtgcat
     6001 tcagattgtc gagcataatc ttaagctgtg ccccatctga aggcatatta tcagcttgtc
     6061 cgcgcaataa ggcatttttg ctttcgcgga tattatagat ctctttagcc accagctcgg
     6121 ccatcttggc ggtagagctg gccatcagaa tctcctcggt caggaattca cgaggattcg
     6181 ctttcttttg gaggactgcg ggggcgggag cagctttttt gcctacactg ctattgctgt
     6241 aaggaacatt gatcgttttc acaatgccat cctctgtcag ttccatgagc ggtgctactg
     6301 tcttatcctt caattttacg aaatacgtag tttcgctgtt gggcacacct acggatttca
     6361 cttttacgct agccagttcc cagtactctt cagggtcggc ggagacgttg gtcagtcgca
     6421 ggtaacgatc agcatatttg ctgaattctc cgggagtata gttgactttg ttggctttta
     6481 tttcaagttc tatttgggtt ttgggaagac tgtaaaccac tccatagtct tttcctcggg
     6541 taacccccgt cagtacttcg gtttgtgcat aggcggacgt tgtcataagt agtcctgctg
     6601 ctataatcaa ctttttcata ttcggttctt tttaactggt tttgaaaaca aagttaatga
     6661 agttattgaa aaaagggtaa gttcttaact tttattcgct tacaagtcgc catgctgtcg
     6721 gcagacaggt gataatatcg cttgcgatca ttccgatcat tccttgcttc ttttgagcga
     6781 catcgcccgc cagtccgtga atgtaagtgc cgattttagc ggcttcctcg gtggggtaac
     6841 cttgggcaag cagtgccagg attactccgg tcagtacgtc accgctacct ccggttgcca
     6901 ttcccggatt tccggttggg ttgaagaaac atttaccttc gggggtgatg atggcggagt
     6961 aggctccttt taaaataatg tgaacatggg cggcacgggc cagttcgcag gccttcatca
     7021 gacgttcgta agagtcctgg catttgccgg tcagacgttc cagttctttc ggatgcgggg
     7081 tgaggatgga acccttcggc aggtgggtaa gtgcatgacg gtggttggcg aggatattaa
     7141 gtgcgtcggc atccactaca acaggagtct ggcagtgttc cagttgttcc aacaaggcag
     7201 cttccgtttc ctcgtttcgt cccagtcccg ggccgatgcc gactgcttga tagtcgtccg
     7261 tgtcggtagg tacggcaaaa caggtttcgt tgatgtcggt ttctacgatt gcttcgggta
     7321 tggaggtttg caagatgtcg ttgttgcaca ttggcgcatg gacagtcagc aaccctactc
     7381 ccgaacggag gcaggcgcgg gcagcgagaa cagaggctcc tgccattcct tttgaaccgg
     7441 caatcaatag tgcatggccg aagttcccct tgtgggcaaa ctgtttgcgt ggcttgatga
     7501 gtgaacggat ttgctctatt tccaacattt cgtagttcgt ttccatctct tcaataccgt
     7561 cttcgcttaa ttggatgtcc agcacttccc attctccgac aaattccgtg ttctctgcga
     7621 aaagaaaggc gagcttcggc agttgcagac tgaaagttac gtcggcacgg ataatattag
     7681 cttttacgtt gaatgtgttt tcttctccca tcagtccgga aggaatgtcg atggctacta
     7741 ccatagcagg ggaggaattg atgtatttca ctacggcagc gaatccgccg ctcaacggtt
     7801 tgttcagacc tgaaccgaat aatccgtcga ttaccagatg gtcgggcgtc aggacgggag
     7861 gtacgaattg ggtactgatt tcgtggaatt ttacttcttc catcatttct accaattctt
     7921 tattggtctg gcagtcgggt gaaagttctc ctttcgtgtt gaagagaaat acctcgattt
     7981 tatatccttt ttcagccatc atgcgggcta cggcgagagc gtctccgcca ttattccccg
     8041 gtccggcaaa gatagtgacc ggcgtttctg tattccatct gtctgtgatg gcttttgtta
     8101 atacggttgc tgcacgttcc atcagatcga ttgatgcaat aggttcgttc tcaatggtat
     8161 aagcgtccaa tttcttgata ctgctgcttg gaaatatttt cattgcgatg ttcttttagt
     8221 tttcggatta caaatgtaca tgattcttct gacttttccc gtttgttgtg ggaagaaaac
     8281 cataattgca acttttaatt catcattagt tctatctttg ggtcagagaa atatctgctt
     8341 ttgaactatt aagtgttaga ataactccgc caaaaaataa ttcaatgcag caccattatg
     8401 aacttacttt tatttctcct gaaaaagatt tcttcatttc atttctcata ttctcattgt
     8461 ttttcgataa acgaaagcta atcaaataga tatcttatga gaaacacttt ttcgaaacgg
     8521 tatttctcat aagttctccc atattttggc tcaaaagcca ccttattctc atagtatttc
     8581 agggtatttc tcatagtcaa aagccatttg ttcttccttt tttctttcag cctgccttat
     8641 ttttatcagg aaatgaagct actatttaga taaaatagtg gctttttgct tgaagatgct
     8701 cattggtctc gattgtccca tatattgtgg gaaagttttc cttcaatata cgggaatact
     8761 ttcctacaaa atacgggaat actttcccaa gccttaggga atcttttccc acaatatgtg
     8821 gaactaagac actgtgtatg gaagcaagca aaaggaatac atagttttat ttattcaatg
     8881 tcagcttccg gcacactaca ctatgagaaa tgaagcaaaa tccgggttat tttgcgaaga
     8941 aactatgaga aatgcctgtt tttaaatcat ttctcatagt ctatcttatt agtttactgc
     9001 cacttgtttc ttatttatga gaatatgaga aatgaaaaat ctttttctgt agaggcgcgg
     9061 atgaaaattg tgtttagttt atcgccatac cttcttaaac aaatttttaa tgcggttccc
     9121 cttattaagc ctttgattat ttgccgtttc cgataaaaat gttatctttg gagatagata
     9181 atgtgcatca catcattttc cagtgctcac aatgaaaatg aattaaaatc taaataacgg
     9241 attgtttaat cttctaaagt ttgcatgatg gaaaagacaa aaattggctt gaatgccggg
     9301 aaagtatggc gcatcttaaa tgaaaaaggt gaactttcaa tgttcgattt gtgccgtgaa
     9361 ttaagtttga cgtttgaaga cgtagctctc gctattggtt ggctggcccg agaagacaaa
     9421 atctttttga ggaaaagaga aggaatgctt tttgccagta tcgaaaatgt cgaatttact
     9481 tttggctaag gtggtagcta acctacattt aagatggatc tccactttat tatttacact
     9541 gctaaaaaag taatgaagtg gatcagtagg atttttatgc tcgtttttac tattccccct
     9601 attattctgt ttgataagag aagcatctaa tctacttttt ctgtaccttt gcaccccata
     9661 aactactaaa cacataaatt catgagtgca ttgaaagggc atccgaaagg cctttatctg
     9721 attttcgcga caagcacggc agaacgtttc agttactacg gtatgcgtgc gatctttatt
     9781 cttttcctga cgcaggcatt attgtttgac aaagaagcgg cagcatccat ctacggcagc
     9841 tataccggac tagtttattt aaccccgttg attggcggat acattgccga taaatattgg
     9901 ggaatccgtc gttccgtgtt ttggggagcg gtaatgatgg cagtcggaca attcctgatg
     9961 tttatgagtg cctccacttt agataatacg aaccttgccc actggatgat gtatggtgga
    10021 ctcggcttcc tgattctagg caatggttgc ttcaaaccca ctgtctcttc tctggtaggt
    10081 cagctctacg aacccggaga caggcggttg gatgctgcat acaccatttt ttatatggga
    10141 gtgaatgtag gctcttttgc tgctcctttg atttgtggtt atctgggtga taccggtgat
    10201 ccgcatgact ttaaatgggg atttcttgca gccggaatca tgacactgtt caccgttgtt
    10261 cttttcgaga ctcaaaagaa taaatatctt ttttctcctt ccggagaacc gattggtatt
    10321 atccccgatg ctaaacgtga aaagaaagaa gacaaggccg accatatctc acacccgaag
    10381 atggacaaac gtaccaaagt acgtaacacc cttgtaatca caattcttac cattgcttta
    10441 atagccttct ttaactatgc atttgaaggc gattgggtga gtatcggcat ttttaccgcc
    10501 tgcattgttt tccctgttct gatcctgtta gacggttcat tgacaaaaat agaacgcagc
    10561 cgtattttcg ttatctatat agtagccttc tttgtcatct tcttctgggc agcctacgaa
    10621 caggcgggag cttctttaac tctcttcgca tccgaacaga cgaatcgtga cattttcggt
    10681 tgggaaatgc cggcttcatg gtttcaatcc ttcaatccac tgtttgtagt tgtcctggca
    10741 tatatcatgc cgggtgtatg gggtttcctg aacaagcgaa agatggaacc tgcttctcct
    10801 accaaacaag cgattggtct gttactcctt tctttaggtt atcttttcat ctgtttcgga
    10861 gtgaaagatg cagttcccgg agtgaaagtg agcatgattt ggctgacagg actttacttt
    10921 attcatacca tgggtgaaat agctttgtcg cctatcggac tttcaatggt aaataaattg
    10981 agtccgctgc gtttcgcctc cctgatgatg ggaatctggt atctgtctac tgccacagct
    11041 aataaatttg cgggaatgtt gagcggactc tatccggaag ccggaaaagt gaagtcaatc
    11101 tttggttatc agattgctac catgtatgat ttctttatgg tattcgtcgt gatgtccggt
    11161 gttgcttcgt tgattctgtt ccttctctcg aagaaattac agaagatgat gcacggggta
    11221 gaataaaaaa tcgtattttt gcaaggttat ttttaaatta ccggttatgg ataccattca
    11281 gataaaagac aaattgttta ccgtttccat taaggaacaa gaaattcaga aagaagtgat
    11341 tcgcgtagcg aacgaaatta accgcgattt ggcaggtaag aatccgcttt tccttagtgt
    11401 gttgaacggt tcgttcatgt ttaccgctga tttactgaag cacatcacca tcccttgtga
    11461 aatctcattt gtgaagttgg cgtcttatca gggcatcact tccaccggag tgattaaaga
    11521 ggtaatcggc ctgaatgaag acattgccgg acgtaccatt gtaatcgtag aagatattgt
    11581 agacacagga ctgacgatgc agcgactgct cgaaacatta ggtacacgca atcccgaagc
    11641 tatccatatc gcttctctgt tggtgaaacc tgaaaagctc aaggtaaacc tcaacattga
    11701 atatgtagcg atggaaattc cgaacgactt tatcgtaggt tacgggttgg attatgatgg
    11761 tttcggacgt aattatcccg atatttatac agtagtagat taatattaaa taggtaccag
    11821 tttaaatggt aaatagtaaa tcgttaaatt gtaaataaca aaatgttgaa catcgtaatt
    11881 ttcggtgctc cgggttcagg aaaaggaaca cagagcgaac gtatcgtaga aaagtatgga
    11941 atcaatcaca tctcgacagg agatgtattg cgtgctgaaa tcaagaatgg cacagaactg
    12001 ggtaaaacag ctaaaggtta catcgaccaa ggtcaattga ttcctgatga attaatgatt
    12061 gatattctgg caagcgtatt cgacagcttc aaagatagca aaggggtaat tttcgacggt
    12121 ttcccaagaa caattgcaca ggcagaagca ttaaagaaaa tgttggcaga aagaggacag
    12181 gacgtttctg taatggttga tctggatgtt ccggaagaag aactgatggt acgtcttatt
    12241 aaacgtggca aggattccgg tcgtgctgat gataacgaag agacaatcaa aaaacgtctg
    12301 catgtatatc attcacagac tgctccactg atcgactggt acaagaacga aaagaaatac
    12361 caacacatca acggcttggg tactatggaa ggtatcttcg ctgaaatctg cgaagcagta
    12421 gataaattgt aataatacaa tattataaat aaataagtca gtagccggag tgttctaatt
    12481 aactgctcta actactgact actttaactc ttaaaaaaaa tatggctgaa tcgaattttg
    12541 ttgattacgt aaagatatac tgtcgctcgg gtaagggcgg aagaggctct acgcacatga
    12601 ggcgcgagaa atattgtcct aacggaggtc ctgacggggg cgatggtgga agaggaggtc
    12661 atatcatctt gcgcggtaac cgtaattact ggacattgct gcacttgaag tatgaccgtc
    12721 atgcaatggc cggtcatggt gaatcgggga gcaaaggacg tagcttcgga aaagacggtg
    12781 cggataaaat aatagaagtg ccctgcggaa cggtagttta taatgccgag acaggggagt
    12841 atctttgtga cgtaacagaa gacggacagg aagtgatttt gctcaaaggc ggtcgcggcg
    12901 gtcagggtaa ctggcatttc aagacggcca cccgtcaggc tccgcgtttt gcgcagccgg
    12961 gagagccgat gcaggaaatg accgttatca tggagctgaa actgcttgcc gatgttggtc
    13021 tggtaggttt cccgaatgcg ggaaagtcaa ctttgctttc ttccatttcg gctgccaaac
    13081 cgaaaattgc cgattacccg tttactacgc tcgaacccaa cttgggcatc gtttcctatc
    13141 acggtggaaa atcctttgtg atggcggaca taccgggtat tatcgaagga gccagtcagg
    13201 gaaaaggttt gggactgcgt ttcttgcgtc atatcgagcg taattcatta ctgctgttta
    13261 tggttccggc agacagcgac gacattcgta aagaatacga agttttgctg aacgaactgc
    13321 gtaccttcaa tcctgaaatg ttggacaagc aacgtgtgtt ggctgtcacc aaaagtgata
    13381 tgctcgatca ggagttgatg gacgagattg aacctacatt gccggaaggc attccacatg
    13441 tattcatatc ttctgtttcc ggtttgggca tctcggtgtt gaaagacatc ctttgggaag
    13501 aactgaacaa ggaaagcaat aagatagagg acatcgttca ccgtccgaaa gacgtgaccc
    13561 gtctgcaaca ggaactcaaa gacatgggcg aagatgaaga catcgtttat gaatatgagg
    13621 aagatgtcga cgatgacgat gatatcgatt atgaatacga agaagaagat tgggaagaaa
    13681 aatgatttca cttacaaaac ataacgagtt gaagggatat aagtcactgg aggcatatcc
    13741 cgaagtagct cattttgtaa ctacgcgtca cgaaggtata agcaccggag cttacggctc
    13801 tttcaactgt tcgccttata ccaacgactc atgtatgaat gtcaatcgca atcagagctg
    13861 gttgtttcag tgcatgaatc atcagataaa ggaattattt attcctgaac agaatcatgg
    13921 ctgtgccagt ctgattatca atgaatcatt ttttaaagaa tcattggaaa tgagacggct
    13981 acttctgcga ggaatggatg ccttgataac taatgtgccg ggatattgcg tttgtgtcac
    14041 gacggcggat tgtgttcctg tattgctgta cgacaaaaaa caacacgttg tggctgccgt
    14101 tcatgccgga tggaaaggaa cagtgaagca tattgtcagt aatgtgatgg accacttgaa
    14161 taagatgttc gggacgcaag gcgaagatgt gatagcttgc atcgggccga gcatttcgct
    14221 cgaatcattt gaagtaggtg atgaggtgta tgatgctttt gaagaaagcg gcttcgatat
    14281 gtctcttatt tctatgaaga agaaggagac gggcaaatat catattgatt tgtgggaagc
    14341 caaccggatt gaattactga atctcggagt gcctgcagaa cagatagaag tggccggaat
    14401 ctgtacctat attcatcatg atgaattctt ctctgcacgt agactgggaa tagattccgg
    14461 tcgtacattg tcgggaataa tgattagaaa gtaataatta gcgtccgtaa tcgcaggacg
    14521 ctgatgattg gtttatgata agttatgttt gaaataaaag tatctaaaga aataaaagac
    14581 gcatgcccgg tttttgccgg agccgccgtg tatgctgcgg tgaagaatac tgcttacaac
    14641 gaagggcttt ggcaggaaat cgacgctttt actaggcaac tgacttccac aacacagatg
    14701 gaagacatca aacatcaacc cgttatcttt gctacccgtg aggcttataa acgttgtggc
    14761 aaagaccccg gacgttatcg tccgtcagcc gaagctctac gccgccgcct gatgcgtgga
    14821 attcctttat atcagattga tacgttggta gaccttatta atttagtgtc tcttcgcaca
    14881 ggacattcga tcggtggttt tgacgcggac aaaatacaag gtacgcatct tgaactcggt
    14941 atcggcaaag caggagaacc gtttgaaggt atcggacgcg atgtattgaa tatcgaagga
    15001 ttacctgtat atcgtgattc tttcggcgga atcggaaccc cgacaagcga ccatgaacgt
    15061 acgaagatgg acctcgaaac tactcatatc ctagccatag tcaacggtta taacggaaaa
    15121 gaaggtttgc gagaagctgc tgaaatgata cagaccttat taagaaacta tacagaatcg
    15181 gatggaggcg aaatcgtatt cttcgaataa ttagaatgag tgctctaaga aaaaagac
//
