LOCUS       gnlProkkaNKHGFJOM_727   3086 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NKHGFJOM_727.
ACCESSION   gnlProkkaNKHGFJOM_727
VERSION     gnlProkkaNKHGFJOM_727
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 00:08:58
            Original ID  :: gnl|Prokka|NKHGFJOM_727
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3086
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3086
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[1049:2273]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1050..2273
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..3086
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3086
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             complement(232..774)
                     /locus_tag="ctg727_1"
                     /transl_table=11
                     /translation="MSTWKGKTRGGTFGYLFFIYLIKYLGITAAYLFLSLVVLYFIPFA
                     PKATKSTWFYARHILKYNRIRSLKMLLLNYYRLGQILIDKVAIGNGKVNQYQFKFEQYP
                     EFLQLLNSEQGVIMIGAHVGNWEIGVPFFDDYGKKINIVMYDAEHRRIKEILEKNGQDR
                     EFKIIPVNEDNLTHVFP"
     CDS             complement(777..1028)
                     /NRPS_PKS="Domain: PP-binding (7-75). E-value: 3.8e-14.
                     Score: 44.9. Matches aSDomain:
                     nrpspksdomains_ctg727_2_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg727_2"
                     /sec_met_domain="PP-binding (E-value: 2.7e-15, bitscore:
                     44.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNEEIIEKIRTTLAEEFEVDIDVIQPDAPLMETLELDSLDLVDM
                     VVLVEKNFGFNVTGQDFAGIKTFQDFYDLVITRMQEAK"
     aSDomain        complement(804..1007)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg727_2_PP-binding.1"
                     /evalue="3.80E-14"
                     /label="ctg727_2_PP-binding.1"
                     /locus_tag="ctg727_2"
                     /protein_end="75"
                     /protein_start="7"
                     /score="44.9"
                     /tool="antismash"
                     /translation="EKIRTTLAEEFEVDIDVIQPDAPLMETLELDSLDLVDMVVLVEKN
                     FGFNVTGQDFAGIKTFQDFYDLV"
     CDS             complement(1050..2273)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (65-405). E-value:
                     2.2e-53. Score: 173.5. Matches aSDomain:
                     nrpspksdomains_ctg727_3_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 295.4; E-value:
                     1.2e-89)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg727_3"
                     /sec_met_domain="APE_KS1 (E-value: 5.5e-161, bitscore:
                     523.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVVITGMGIYSCIGKNLDEVKDSLYNGKSGIGIDPVRKELGYF
                     SALTGILERPDLKKLLDRRKRLCLPEQGEYAYLATLEAFRNAGIDDAFLEANEVGILYG
                     NDSSAAPVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACA
                     SGSHAIGMGYLLIKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAEPEKASKPFDK
                     RRDGLIPSGGAASLVLESYESAVKRGAPILAEVIGYGFSSNGDHISVPNVDGPKRSLQM
                     AIKDAGIALEQISYINAHATSTPVGDLNEAKAIAEVFEGHHPYVTSTKSMTGHEMWMAG
                     ASEVIYSILMMNNGFIAPNLNFEEADEASAQLNIPTQRVNLEFDTFLSNSFGFGGTNST
                     LIIRQIKE"
     aSDomain        complement(1059..2078)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg727_3_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.20E-53"
                     /label="ctg727_3_PKS_KS.1"
                     /locus_tag="ctg727_3"
                     /protein_end="405"
                     /protein_start="65"
                     /score="173.5"
                     /tool="antismash"
                     /translation="RLCLPEQGEYAYLATLEAFRNAGIDDAFLEANEVGILYGNDSSAA
                     PVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACASGSHAI
                     GMGYLLIKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAEPEKASKPFDKRRDGLI
                     PSGGAASLVLESYESAVKRGAPILAEVIGYGFSSNGDHISVPNVDGPKRSLQMAIKDAG
                     IALEQISYINAHATSTPVGDLNEAKAIAEVFEGHHPYVTSTKSMTGHEMWMAGASEVIY
                     SILMMNNGFIAPNLNFEEADEASAQLNIPTQRVNLEFDTFLSNSFGFGGTNSTLIIRQI
                     "
     CDS             complement(2300..3028)
                     /NRPS_PKS="Domain: PKS_KR (3-169). E-value: 1.3e-16. Score:
                     52.9. Matches aSDomain: nrpspksdomains_ctg727_4_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     213.3; E-value: 6.4e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg727_4"
                     /sec_met_domain="adh_short (E-value: 1.1e-36, bitscore:
                     114.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYALVTGGSRGIGRAVSCKLAEMGYFILINYQSNDAEAEKTLQL
                     VQEKGSNGEIMKFDVTDPAAIALALNNWASQHPDEYIEVLINNAGIRKDNLMLWMTGEE
                     WNKVLDISLNGFFYVTQPLLKNMLVKRYGRIVNIVSLSGIQGMPGQANYSAAKGGVIAA
                     TKALAQEVAKKKVTVNAVAPGFIRTDMTEGIDENEWKKHIPAGRFGTAEEVADLVGFLA
                     SPASSYITGEVISINGGLYT"
     aSDomain        complement(2522..3019)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg727_4_PKS_KR.1"
                     /evalue="1.30E-16"
                     /label="ctg727_4_PKS_KR.1"
                     /locus_tag="ctg727_4"
                     /protein_end="169"
                     /protein_start="3"
                     /score="52.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGGSRGIGRAVSCKLAEMGYFILINYQSNDAEAEKTLQLVQE
                     KGSNGEIMKFDVTDPAAIALALNNWASQHPDEYIEVLINNAGIRKDNLMLWMTGEEWNK
                     VLDISLNGFFYVTQPLLKNMLVKRYGRIVNIVSLSGIQGMPGQANYSAAKGGVIAATKA
                     LAQ"
     CDS_motif       complement(2954..3016)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg727_4_0001"
                     /evalue="2.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg727_4"
                     /protein_end="25"
                     /protein_start="4"
                     /score="13.5"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAVSCKLAEMG"
ORIGIN
        1 cttttgttcg tactaccggt tccgctatta taaaatgaaa acggtaagtt cttcccggtt
       61 ccctcattgc aaagtagaat accaccggaa ctttcattcg cgaagcgagc aggaaaggac
      121 cggcaggaaa aggagctttc tgtcccagta aaattcctgg cagaagtttc tctttgttca
      181 gataacggtc gccttggaaa catacatatt ctttttggtt gatcgcctcg gttatgggaa
      241 aacgtgtgtc aggttgtctt cattgacagg gataatctta aattccctgt cctgaccgtt
      301 tttctccagg atctctttga ttctacgatg ttcggcatcg tacatcacga tattgatttt
      361 ctttccgtaa tcatcaaaga aaggaacgcc tatttcccag tttcccacat gggcgccaat
      421 cataatcact ccctgttcac tgttcagcag ttgcagaaac tccggatact gctcgaattt
      481 gaactgatat tgatttactt ttccattacc gatggctacc ttgtcaatca ggatttgtcc
      541 taatcggtaa tagttgagta gtaacatttt caaagaacgt atcctattgt atttcagaat
      601 gtgacgggca taaaaccagg tgcttttggt tgctttcgga gcaaacggta tgaagtagag
      661 cactaccagg cttagaaaaa gataagcggc agtaatgccc agatacttaa tcaggtaaat
      721 aaagaataag tatccgaacg ttcctccccg ggttttgcct ttccacgtcg acatatttac
      781 ttggcttcct gcatacgggt gataacgaga tcgtagaagt cctggaaggt tttgatacct
      841 gcaaagtctt gtccggttac gttgaaaccg aaattctttt ctaccagtac caccatgtcg
      901 accaagtcca gactgtccag ttcaagagtt tccattaacg gcgcatccgg ctggatgacg
      961 tcgatgtcta cttcaaactc ttctgccaga gttgttctta ttttctcgat gatttcttcg
     1021 tttgtcatat atctgttttc tttagtaatt tattctttga tttggcgtat aatcagggtg
     1081 gaattggttc ctccgaatcc aaacgagttg gaaaggaacg tatcaaattc cagatttacc
     1141 cgttgggtag gtatattcaa ctgtgcggaa gcctcgtccg cttcctcgaa attgaggttg
     1201 ggagcgatga aaccgttatt catcatgagg atggagtaaa tcacttcact ggcacctgcc
     1261 atccacattt catgtccggt catagacttc gtggaagtga catacgggtg atgtccttca
     1321 aatacttccg caatggcttt cgcttcgttc aggtcgccta ccggagtgga agtggcgtgt
     1381 gcgttgatat aactgatttg ttcgagtgca atacccgcat ctttgatggc catctgaaga
     1441 gaacgtttcg gaccgtccac gttcggtacg gagatatgat ctccattgga agagaaaccg
     1501 taaccgataa cttcggccaa aatgggagct ccccttttta ctgccgattc atagctctct
     1561 aataccagac tggcggctcc tccactcgga atcagtccgt cacgtcgttt atcaaaaggt
     1621 ttggaggctt tctcgggctc tgcttcctgg gtggaaaatg cgcttagccc gtcgaaactg
     1681 ccgaccgcat aaggatttac ttcttgtgcg ccaccgcaaa gaatacaatc ctgcaatcct
     1741 gatttaatga gcagataccc catgccaata gcatgagaac cacttgcaca agctccggca
     1801 atggtgaagt taactcctct aagcttgaag ataaccgaca ggttcattgt cacggtagaa
     1861 ttcatcgact ggaaaataga accggaacct accaacgctg tgtttttctt ttcacgaatg
     1921 atgtccactg cgttgatgac aggggcagca ctactatcat tgccatacaa gatacccact
     1981 tcattagctt cgagaaaagc atcgtcaata ccggcgttgc ggaaagcctc caaagtagcg
     2041 agataagcat actctccctg ttccggcagg cagagacgtt tacgacgatc taatagtttc
     2101 ttcaagtcgg gacgttccaa tatgcccgtt aatgcagaaa aatagcccag ttctttccgt
     2161 accggatcta tgccaatccc cgatttccca ttgtatagtg agtcttttac ttcatccagg
     2221 ttcttgccga tgcaagagta aattcccatt cccgtgataa caactctttt cattattttg
     2281 tctattctat gcttttgttt taagtatata gtcctccgtt gatggaaatc acctctcctg
     2341 tgatatagga tgaggccgga gatgccagaa aaccgacgag atcggcaacc tcttccgcag
     2401 taccgaaacg tcctgcagga atgtgttttt tccattcgtt ctcatcaatc ccttccgtca
     2461 tatccgtgcg gataaatcca ggagcaactg cgttgactgt tacctttttc ttggccactt
     2521 cttgtgccag tgctttggta gcagctatta cgccaccttt ggctgcggaa taattggctt
     2581 gtccgggcat tccctgaata cctgacaagg atacgatatt gacaatacgt ccataacgtt
     2641 tgaccagcat attcttcaat aaaggttgtg tcacataaaa gaatccgttc agactgatat
     2701 cgagcacttt gttccattct tctcctgtca tccaaagcat caggttgtct ttgcggatgc
     2761 ccgcattgtt aatcagtact tcgatgtatt cgtcaggatg ttgtgacgcc cagttgttca
     2821 aggcaagggc aatagcggca gggtctgtca catcgaactt catgatttct ccgttacttc
     2881 ctttttcctg cactaactgc aacgtttttt ccgcttctgc gtcgttactc tgataattaa
     2941 tcagtataaa gtagcccatt tccgccagtt tgcaactgac agcacggccg atacctcgac
     3001 ttcctccggt tactaatgcg tatttcattt tatttatttt cttttttgag atagtccatc
     3061 attctttcta tctctttgta tttagg
//
