LOCUS       c00247_gnlPro..         9682 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NKHGFJOM_247.
ACCESSION   c00247_gnlPro..
VERSION     c00247_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 03:28:36
            Original ID  :: gnl|Prokka|NKHGFJOM_247
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9682
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..513
                     /locus_tag="ctg247_1"
                     /transl_table=11
                     /translation="GKYKGCGHGKALLQSAIDDAKLQGKDGLVTVVGTSKFHFMSDTKW
                     LLRQGFQTIEKLPYGFSLLALKINPAAPDPSFNDSVLTGECPDRDGIVVYYTHRCPFTE
                     FHVRGSLVNAAKSKDLPLKIIELETMEQAQNAPTPATIFTLFYNGKFVTTDLSACIEAR
                     LGKALGL"
     protocluster    1..9682
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2937:7797]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2938..7797
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..9682
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9682
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             668..2425
                     /locus_tag="ctg247_2"
                     /transl_table=11
                     /translation="MRFFVCILVLLFVHNQFSRADKTLIDDSLYTEKYIRNIYIPEPRR
                     ALQLLDEAENRKTIPLRVVNELRSLSYSNMYMNKLAFMYARKAYLLDSLYQKDPKHMLK
                     MTVHLAEFSAMMSKYNESMRYALDGIRQAQELGNREAKARLFFCMGENNWRLSFKDKAY
                     DYFNRTIELLRGSKEKREMMLLSYYYGAEMSFLMNDSRIEEALKVGFEREKQIERLKAV
                     PQISEDYIDGQYSYLYAKLAYIYCMEKKYEKAEQYYQKYLSKKESHTPDGKMYSVPYLV
                     LSGQYEKVIDNCRGFKELMRTQQDTLNEQYLTVLRQEVKAYLGMHKYKEAAEIRETILT
                     ITDSINTRDRNNAALELNAMYGVSEKEEYIAEQAFQLKIRNITLCFLACIVVLTLFVVW
                     RLWHFNHIVEYKNRMLARLINEKFANRKDGNQLSEVYEQLAVVSEVEPERISPEELEEL
                     ANDTDKESGEEEENKKIFQELNDIVIQKQLYLSSELSREDLAQIVHLNNARFARMIREC
                     TGTNFNGYINELRINYAIELMKKHPNYTIRAIADEAGFNSTPILYNLFKKKTGMTPYEF
                     KKAQDSLQN"
     CDS             2491..2853
                     /locus_tag="ctg247_3"
                     /transl_table=11
                     /translation="MIQVRIKRVYEDFSETDGYRVLVDKLWPRGMKKEWLKYDYWAKDI
                     TPSSTLRRWFHEDIPGHWEDFVIQYQKELDASPSMADFLTLIKPHPVITLLYASKEPVY
                     NHARILRDYLEMRLKE"
     CDS             2938..4170
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg247_4"
                     /sec_met_domain="HBT (E-value: 1.4e-18, bitscore: 56.5,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKMLELGNYGGFILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNG
                     FALFTYHDDTIITDSPENEHIQNEARLNNLQIIKEEEFSAAVDFAPCKCMLVSDDEEAL
                     VGLEDHWKRRLNGALDVFRSEPYFLEVVPCAIDKANSLGALLEVLDVKREEVIAVGDGV
                     CDVTMIQLAGLGVAMGHSQDSVKACADYVTASNEEDGVAVAVEKAIIAEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALAETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVGTVVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             4167..5282
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg247_5"
                     /sec_met_domain="Chorismate_bind (E-value: 2.4e-57,
                     bitscore: 183.6, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDEEISNLTTIDAFIQRKQPFAVYRIPGEKVPRLLTQAEGVVRL
                     IYDLKELNGQRGFVIAPFQVNESCPVVLIQPDQWGQPLPVDDDTEEDREIALRLQGQES
                     FLTSSTEEYTACFHTFINALRDRTFDKLVLSRHLTVDKVADFSPSSIFRAACKRYIHSY
                     IYLCYTPQTGIWLGSTPEIILSGEKDEWHTVALAGTQPLQDGRLPQVWDEKNRKEQDYV
                     SSYIRRQLLSLDIHATENGPYPAYAGALSHLKTDFRFALKDNKGLGDLLKVLHPTPAVC
                     GLPKEEAYQFILQNEGYDRRYYSGFIGWLDPEGRTDLYVNLRCMHIEDKQLTLYAGGGL
                     LASSELNDEWLETEKKLQTIKRLIAVPPLKS"
     CDS             5302..6969
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg247_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.9e-08, bitscore:
                     21.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTDKKNILQLVALLEAHGITKVVLCPGSRNTPIVHTLSNHPNFT
                     CYPVTDERSAGYFAIGLALNGGKPAAVCCTSGTALLNLHPAVAEAFYQNVPLVIISADR
                     PAAWIGQMDGQTVPQPGVFQTLVKKSVNLPEIHTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINIPISEPLFQFTVDSLPEVRVITRYQGLNVYDRDYNDLVDRMNKYQKRMIIIGQMN
                     LIYLFEKRYIKLLYKHFAWLTEHIGNQTVPGIPVKNFDAALYAMPEEKVDQMVPELLIT
                     YGGHVVSKRLKKLLRQHPPKEHWHVSPDGEVVDLYGSLTTVIEMDPFEFLEKIASLLDN
                     RTPEYPRVWENYCKIIPEPEFAYSEMSAVGTLLKALPESCALHLANSSVVRYAQLYSIP
                     STIEVCCNRGTNGIEGSLSTAVGYAAASDKLNFIAIGDLSFFYDMNALWNVNVRSNLRV
                     LLLNNGGGEIFHTLPGLDMSGTSHKFIAAVHKTSAKGWAEERGFLYLQAQNDEELAEAM
                     KTFTQPEAMEQPVLLEVFTNKNKDARMLKNYYHQLKQK"
     CDS             6973..7797
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg247_7"
                     /sec_met_domain="ECH_1 (E-value: 8.2e-83, bitscore: 266.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYDDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKQYPKFP"
     CDS             7970..8995
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg247_8"
                     /sec_met_domain="MR_MLE_C (E-value: 1.5e-28, bitscore:
                     89.1, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNCKIEIIPRLLHFKQPAGTSRGTYTTRKVWYLHFTSPDFPGRVG
                     IGECAPLPALSCDDLPDYEDILVKVCRKVEREQGRLDMDGLCDYPSILFGLETAIRHFF
                     AGNWALCDTAFSRGEVGIPINGLIWMGDFQNMLSQIEKKMEAGFRCIKLKIGAINFEEE
                     LTLLRHIRTHFSSKEIELRVDANGAFSPVDAMEKLKRLSEFDLHSIEQPICAGQWEEMA
                     RLAAESPLAIALDEELIGCNTLERKQELLSTIRPQYIVIKPSLHGGICGGDEWITEAEK
                     QQIGWWITSALESNIGLNAIAQWCATFSNPLPQGLGTGALFTDNVEVPLEIRKDCLWFC
                     K"
     CDS             9017..9682
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 58.9; E-value:
                     1.2e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg247_9"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-19, bitscore:
                     58.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFDRKQQRLLLEGKEYTFEDISRLIAGGAEAHSPASWDLYLFLN
                     EWFNDSPVIIVHTSGSTGTPKELIVRKDQMMQSARLTCEFLDLKKGETALLCMNLRYIG
                     AMMVVVRSLVAGLNLIVRPASGHPLADIKEPLRFVAMVPLQVYNTLQVPEEKERLKQTD
                     ILIIGGGAIDEALEAEIKHLPTAVYSTYGMTETLSHIALRRLNGTLASEHYYPFSSVKL
                     "
ORIGIN
        1 ggtaaatata aaggatgcgg gcatggtaag gctttgctgc agtctgctat tgatgatgcg
       61 aaattgcagg gaaaagatgg tttagttacc gtagtgggca cttctaaatt tcattttatg
      121 agtgatacaa aatggctgct gcgacaaggt ttccaaacta tagaaaaact tccttacgga
      181 ttcagtttgt tggctttgaa aataaatccg gctgctcccg atccttcatt caacgacagt
      241 gtattgacag gtgagtgtcc tgaccgggat ggaatagtag tgtattatac tcatcgctgt
      301 ccgtttactg aattccatgt tcgcggttct ttggtcaatg cagccaagag taaggatctc
      361 ccattaaaaa taatagaatt agaaaccatg gaacaagcac aaaatgcgcc tacaccagcc
      421 actatcttta ctctttttta taatgggaag tttgttacaa ccgatttgag cgcgtgtatt
      481 gaagcccggt tggggaaggc tttaggcttg tgattctgtg agatgaagat ttatcagaaa
      541 ctaggattgg gataagaaga tagctaatgt ttcttatttt aattttgcaa aattaagatg
      601 caccttgcac tttttgtgga aaatacatat ctttggatgc tgaatgatta aaacacggta
      661 agatcttatg cgtttttttg tatgtatttt ggtgctttta tttgtacaca atcaattttc
      721 gagggctgat aaaactttaa ttgatgattc tctgtatacg gagaaatata tcaggaatat
      781 ttatattccc gaacctaggc gtgctctgca attactggac gaagcggaga acaggaaaac
      841 gattcctttg cgggttgtaa atgaattgcg tagtttatca tatagtaata tgtatatgaa
      901 taaactagca tttatgtatg caaggaaagc ttatttgctt gattccctat atcaaaaaga
      961 tccgaaacac atgctgaaaa tgacagtaca tttggctgaa ttttcggcaa tgatgagcaa
     1021 atataatgaa agtatgcgtt atgcattaga tggaatcagg caggcgcaag agttagggaa
     1081 cagggaagcc aaagccaggt tatttttctg tatgggagag aataattgga gattatcttt
     1141 taaagataaa gcatacgatt attttaaccg gactattgag cttttgcggg gctcaaagga
     1201 gaagcgggaa atgatgttgc tctcttatta ctatggagca gaaatgagct ttttaatgaa
     1261 tgattctcga attgaagagg cattgaaagt gggttttgag cgtgaaaagc aaattgaacg
     1321 gcttaaggca gtacctcaaa tctctgaaga ttatatagac ggtcaatata gttatttata
     1381 tgccaaatta gcctacatct attgcatgga gaagaaatat gagaaggcgg agcaatatta
     1441 tcagaaatac ttatcaaaga aagaatctca tactcccgac ggaaaaatgt actcggttcc
     1501 ttatttagtg ctttccggac aatatgaaaa ggttattgat aattgcaggg ggttcaagga
     1561 attgatgaga acccagcagg atactttgaa tgaacagtat ctgactgtcc ttcgacagga
     1621 agtgaaggca tatttgggta tgcataaata caaagaagct gccgagatac gtgaaacgat
     1681 tttaactata acagatagta tcaatacccg ggatagaaac aatgctgcat tggaattgaa
     1741 tgcaatgtac ggcgtctctg aaaaagaaga atatattgcc gaacaggctt ttcaattaaa
     1801 aataaggaat attaccctct gttttcttgc atgtattgtt gtactgactc tgtttgtcgt
     1861 ttggcgtttg tggcatttca atcatatagt cgagtataag aacaggatgc ttgccaggct
     1921 tataaacgag aaatttgcta atagaaaaga tgggaaccag ttatcggaag tatacgaaca
     1981 actggctgtt gtgtcggagg ttgaaccgga acgtatttca cccgaagaac tggaagaact
     2041 tgctaacgat acagataaag aaagtgggga agaagaagag aataagaaga tatttcagga
     2101 actgaatgat atcgttattc agaaacagtt atatctttct tcagaattgt cgagagaaga
     2161 tctggcacaa atcgtacatc tgaataacgc acgttttgcg aggatgataa gagaatgtac
     2221 cgggaccaat ttcaatggat atatcaatga attgcgcatt aattatgcca ttgaactgat
     2281 gaaaaagcat cctaactata cgatacgtgc cattgcagat gaggccggat ttaatagcac
     2341 cccgatttta tacaatcttt ttaagaaaaa gacgggaatg actccttacg aatttaaaaa
     2401 agcacaggat tcgttacaga attgagtgga ttctgctaaa caattttcgc attttccggt
     2461 ttatctattt ataattaact attaatagag atgatacagg taaggataaa gcgggtttac
     2521 gaagattttt cagaaacaga tggctaccgg gtactggtag ataaattatg gccacgtgga
     2581 atgaagaaag aatggcttaa gtacgattat tgggcaaaag acatcacacc gtcttccaca
     2641 ttgcgtagat ggtttcacga agatattccc ggacactggg aagactttgt catacagtat
     2701 cagaaagaac tagatgcttc tccctcaatg gctgattttc tgactcttat caagccacat
     2761 ccggtgataa cattgcttta cgcttccaaa gaaccggtgt ataatcatgc ccgtatcctc
     2821 cgcgattatc tggaaatgcg tttgaaagag tgaaattaaa gtaattttta tctgtttacg
     2881 ctttctgtcg ttcactcaat ttcctacctt tgtaatctaa atcaaaatcg tgtaatcatg
     2941 aagtataaat tattggttct tgatgtagac ggaacactcc tcaatgatgc gaaagaaatt
     3001 agtaagcgta cattggctgc cctgttgaag gttcagcaaa tgggagtacg tattgtgctg
     3061 gcatccggca gacctactta tggcctgatg ccgctggcca agatgcttga acttggaaac
     3121 tatggaggtt ttatcctttc ctataatggc tgtcagatta tcaatgcaca aaacggggaa
     3181 attctgtttg aacgtcggat taatcccgaa atgttgccgt atctggaaaa gaaagcccgt
     3241 aaaaacggtt ttgccttatt cacttatcat gatgatacga tcataacgga ttctcctgaa
     3301 aatgaacata tccaaaatga agcccggttg aataacctgc aaataatcaa agaagaagaa
     3361 ttttctgctg ccgttgattt tgctccttgt aagtgtatgc tggtgagcga tgacgaagaa
     3421 gcactggttg gtctggaaga tcactggaag agacgattga acggagcgtt ggacgtattc
     3481 cgttcggaac catattttct ggaagtagtt ccctgcgcta tcgacaaagc caactctttg
     3541 ggtgctttgc tggaggtact ggatgtgaag cgtgaggaag tgattgctgt gggcgacggt
     3601 gtgtgtgacg taacaatgat tcagttggcc gggctgggcg tagctatggg acattcacaa
     3661 gactcggtga aagcctgtgc cgactatgtg actgcttcga atgaggaaga cggagtggcc
     3721 gttgcagtgg agaaggctat tatagccgaa gtgcgtgcag ccgaaattcc ccttgaccaa
     3781 ctgaatgcgc aggcacgcca tgcattaatg ggaaacttgg gaattcaata tacatacgcc
     3841 gacgaagatc gtgtggaagc aacgatgccg gtagaccatc gtacccgtca gccttttggt
     3901 attttgcatg gtggagctac tcttgcgttg gcggaaacag ttgccggact cggttcgatg
     3961 attctttgcc agccggacga gattgtagta ggaatgcagg tcagcggaaa ccatatatct
     4021 tctgcacatg aaggagatac cgtgcgtgca gtaggaacag ttgtacataa aggacgttcc
     4081 tcccacgtat ggaatgtaga cgtgtttact tcaacaaaca aactggtgtc ttccatacgg
     4141 gtagtcaaca gtgtgatgaa aaagagatga ccgacgaaga aataagtaac ttgacaacta
     4201 ttgatgcatt tattcagcgg aagcagccgt ttgctgttta ccgtattccc ggagagaaag
     4261 ttccccgtct gttgacgcag gcggaaggag tggtccgttt gatatacgat ttgaaagaac
     4321 tgaacggaca gagaggattt gtaattgctc cgtttcaggt gaatgagtca tgtccggttg
     4381 tattgattca acccgatcag tgggggcagc ctttaccggt ggatgatgat acggaagaag
     4441 accgggagat agccttgcgc ctgcaagggc aagaatcatt tctgacttct tccacggaag
     4501 aatatacggc atgctttcat acctttataa atgcgttacg tgacaggact tttgataaac
     4561 tagtgctttc ccgtcatctt acagttgata aagtagctga tttctctcct tcgtccatct
     4621 ttcgggcggc ttgtaaacgt tatattcatt cgtatatata cttatgttat actccgcaga
     4681 cagggatctg gctgggaagc actcccgaaa tcattttatc gggtgagaaa gacgaatggc
     4741 atacggttgc gctggccgga acacagcctt tgcaagatgg cagactgccg caagtatggg
     4801 atgaaaagaa ccggaaggaa caggattatg tatcttctta tatccgtcgt cagcttcttt
     4861 cactggatat ccatgctacg gaaaacgggc catatcctgc ttatgccggt gctttgtcac
     4921 atttaaaaac cgatttccgg ttcgctttga aagataataa aggtttggga gaccttctga
     4981 aagttttgca tccgacacct gccgtatgcg gcttgccgaa ggaagaagcc tatcagttta
     5041 ttttgcagaa cgaaggttac gaccgccgct attactccgg ttttatcgga tggctcgatc
     5101 cggaagggcg aacagacttg tatgtaaacc tgcgctgtat gcatatcgaa gataaacaac
     5161 tcactcttta tgccggcggt ggattattgg cctcttcgga actgaatgac gaatggctgg
     5221 aaacggagaa aaagttgcaa accatcaaac ggctgattgc agtgcctcct ttaaaatcat
     5281 aaactactaa taattatcat catgtataca gacaagaaga acatactcca gttggttgcg
     5341 ttgcttgagg cgcatgggat tactaaggtt gtgttgtgtc cgggtagtcg taacaccccc
     5401 atagtgcata ctttgtctaa ccatccgaat tttacctgct atccggtgac ggatgaacgg
     5461 agtgccggct attttgccat cggtcttgcg ttgaatggtg gtaagcctgc tgctgtctgc
     5521 tgcacttccg gtactgcatt attaaacctt catccggctg tggcagaagc attttatcaa
     5581 aatgttcctc tggtcattat ttctgcagac cgtcccgctg cctggatcgg acaaatggac
     5641 ggacagactg taccacaacc aggcgtattt cagacgctgg tcaagaagtc ggtaaacctt
     5701 ccggagattc atacggaaga agatgaatgg tattgcaatc gtctggtgaa tgaagcattg
     5761 ctggagacga accatcatgg aaaaggaccg gtacatatca atatccctat ttctgaacca
     5821 ttgttccagt ttacggtcga ttcgcttcca gaagtgcgtg tcataacccg ttatcagggg
     5881 ttgaacgtct acgatcgtga ttataacgat ttggtcgacc ggatgaataa ataccagaag
     5941 cgtatgatta tcatcggtca gatgaatctt atctatctgt ttgaaaaaag atatatcaag
     6001 ttattatata aacattttgc ctggttgacg gaacatatcg gcaaccagac agttcccggt
     6061 attccggtaa agaacttcga tgcggcgctt tatgccatgc ccgaagagaa ggtagatcag
     6121 atggttccgg agctgctgat tacttatgga ggacatgtcg tttccaaacg attgaagaag
     6181 ttgctccgtc agcatccgcc taaagaacat tggcacgtat cgccggacgg tgaggtggtc
     6241 gatttgtatg gctcattaac tacggtgatc gaaatggacc cgttcgagtt tctggagaag
     6301 atagccagtt tgctggacaa tcggactcct gaatatcccc gtgtgtggga aaactattgc
     6361 aagatcattc ctgaaccgga gtttgcttat tcggaaatgt ctgctgtcgg tacgttgttg
     6421 aaagccttgc cggagtcatg tgcgttgcat ctggctaaca gttcggtggt gcgctatgcg
     6481 caattatact ccattccttc tacgattgaa gtttgttgca accggggaac aaacggcatt
     6541 gaaggctcgc tgtctacggc tgtcggttat gcggcagctt ccgacaaact gaactttata
     6601 gctatcggag atttgagctt cttctatgat atgaatgcgt tgtggaacgt caatgttcgc
     6661 tccaatctgc gtgttcttct gttaaataat ggaggaggag agattttcca taccttgccg
     6721 ggattggata tgtcgggtac ctcacataaa tttattgcgg cagttcataa aacatcggcc
     6781 aaaggttggg cagaagagcg tgggtttctc tatctgcaag cgcaaaatga cgaagaactg
     6841 gctgaagcga tgaaaacttt cactcaaccg gaagctatgg agcagcctgt gctcttggag
     6901 gtgtttacca acaaaaacaa ggacgcgcgc atgttgaaga attattatca tcaattaaaa
     6961 caaaaataga ttatgtcaac acaaagagag tggacaacca ttagagaata cgacgatatt
     7021 ctttttgatt attataatgg aattgcccgt atcacgatca accgtgagcg ctatcggaat
     7081 gcgtttactc cgacaactac tgctgaaatg agtgacgcat tgcgcatctg ccgtgaagaa
     7141 gcggatattg atgtgattgt gattaccgga gccggtgata aggcgttttg ttcgggtggc
     7201 gaccagaatg tgaaaggacg tggcggatat atcggaaaag acggtgtgcc tcgtctaagc
     7261 gtattggatg tgcaaaagca gattcgcagc atcccgaaac cggtgattgc tgccgtgaac
     7321 ggttttgcta ttggtggcgg acatgtgctt catgtggtat gtgatttgtc cattgcgtcg
     7381 gaaaatgcta ttttcggtca gacgggtcct cgtgtaggta gctttgatgc cggattcggt
     7441 gcgtcttatc tggcacgtgt ggtaggtcag aagaaagcac gcgaaatctg gttcctctgt
     7501 cggaagtata atgcacaaga agcattggac atgggattag tgaataaagt agttcctttg
     7561 gagcagttgg aagatgaata tgtgcagtgg gcagaagaaa tgatgctgct tagtccgttg
     7621 gctttgcgca tgattaaagc aggattgaat gccgaactgg atggtcaagc aggtattcag
     7681 gaattggcag gtgacgcaac gttgctctat tacctgactg atgaagcaca ggaaggaaag
     7741 aatgcgtttc tggagaaacg taaaccgaac ttcaaacaat atccgaaatt cccttaaaat
     7801 cggctttgcc acagagtacc acagagtttg cttttcctgc gtttaagccc gattttctgc
     7861 aaagcaagac tgtggaggag agaatggtag gagaactgca agagatataa cttattaaaa
     7921 cttcgtgagg ctctgtgtta ttctgtggtg aattgaaaaa ttattcacga tgaattgtaa
     7981 aatagaaatt attccccgat tgctccattt caagcaacct gccgggactt ccagaggaac
     8041 atatactacg cgtaaagttt ggtatcttca ttttacctct cctgacttcc ctggcagagt
     8101 gggaataggg gagtgtgcac ctttgcccgc tttaagttgt gacgatcttc ctgattacga
     8161 agatatatta gtgaaagtct gccggaaagt agagagggaa caaggcagat tggatatgga
     8221 tggcttgtgt gactatcctt caattttatt tggtctggaa acggccatcc ggcatttctt
     8281 tgcaggaaac tgggctttat gtgatacggc tttctcacgt ggagaagttg gtattccgat
     8341 taacggcctt atttggatgg gagattttca gaacatgtta tcccagattg agaaaaagat
     8401 ggaagccgga tttcgttgta tcaagttaaa gataggtgcc atcaatttcg aagaagaact
     8461 gacattgttg cgccatattc gtacgcattt ctcttctaaa gaaatagagt tgcgtgtaga
     8521 tgcaaatggt gctttctcac ccgtggacgc aatggaaaaa ctgaaacgtc tgtccgagtt
     8581 tgatttacat tctatcgaac agccaatctg tgccggacaa tgggaggaaa tggctcggct
     8641 tgctgccgaa tctccattag cgattgcttt ggatgaagaa ctgataggat gcaatacgtt
     8701 ggaaaggaaa caggagctgc tttcaacaat tcgtccgcaa tatatcgtta ttaaaccttc
     8761 tcttcatgga ggaatatgcg gaggagacga atggattacc gaagctgaaa aacaacagat
     8821 cggctggtgg ataacttccg ctctggaatc aaacattggg ctaaacgcca ttgcccagtg
     8881 gtgtgcaaca ttcagcaatc cgttgccaca gggactggga acaggggcgc tctttacaga
     8941 caacgtggaa gtgcctcttg aaataagaaa agattgttta tggttttgta aatgatagta
     9001 tttaaaagat attccgatga tattcgatcg aaaacaacaa cgcttgttac tggaaggaaa
     9061 agaatatact tttgaggata taagccgatt aatagcagga ggagcggagg ctcattctcc
     9121 tgctagttgg gatttatatc ttttcctgaa cgaatggttt aacgattctc ctgtcatcat
     9181 tgttcataca tcaggctcta cgggtacacc taaagagttg attgtacgta aagaccagat
     9241 gatgcaaagt gcgcgtctga cttgtgagtt tctggatttg aagaaaggag agacggcatt
     9301 actttgtatg aatcttcgtt atattggtgc aatgatggtg gtcgtgcgtt cgttggttgc
     9361 aggcttgaat ttgattgtac gtcctgcttc cggtcatcct ttagcggata taaaagagcc
     9421 tttgagattt gtggcaatgg ttcccctgca agtttataat acgttgcaag ttcccgaaga
     9481 gaaagaacga ttgaaacaga cggatatttt gattataggt ggtggagcta ttgatgaggc
     9541 tttagaggcg gagatcaaac atcttccgac tgccgtctat tctacctatg gcatgactga
     9601 aactttatct catattgctc ttcgtcggct gaacggaaca ttggcttcgg aacattatta
     9661 tccgttttct tcagtaaaac tg
//
