LOCUS       c00443_gnlPro..        17047 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NKHGFJOM_443.
ACCESSION   c00443_gnlPro..
VERSION     c00443_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 03:28:36
            Original ID  :: gnl|Prokka|NKHGFJOM_443
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17047
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17047
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4074:7047]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4075..7047
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17047
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17047
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(250..936)
                     /locus_tag="ctg443_1"
                     /transl_table=11
                     /translation="LRAYLSTGLINPNNKDDLAKIAQAMLINLDEFEGMNGRELNIFKD
                     LVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVDSMEFIKIN
                     YAQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPERFEKV
                     HYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIIDTEQVK
                     SNRLYE"
     CDS             1180..1410
                     /locus_tag="ctg443_2"
                     /transl_table=11
                     /translation="MVGAAEVGVDQILNRLDGARIAQFVHLHPNAVFHHFVENMERFRL
                     LRVRFPSAIFHDMKHFVVACIVIFFDMLLNL"
     CDS             1675..2157
                     /locus_tag="ctg443_3"
                     /transl_table=11
                     /translation="MVVECHLFGEGIVVWCCRLFLFAGCPFLLLRLEEHRWLFHDDSCG
                     IGIEINIRIVREQASAANILSGSVDLNSAELGIKGSDFVISGMMEIFNFLNRFGQCPVR
                     PAYTYHDFQSHSFGTDESDAGVGTLFCQCEDACQCFLCLMVDVYHDVSQILDESCV"
     CDS             complement(2455..2685)
                     /locus_tag="ctg443_4"
                     /transl_table=11
                     /translation="MYYPDQPFHIRTYKKSELAHLYNPNVCLKVALQILRRWIVYNLPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             3557..4003
                     /locus_tag="ctg443_5"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRADRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDENGKAADTRTSRQKEAMHRLVSELL
                     QRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIEEFES"
     CDS             complement(4075..4803)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 73.2;
                     E-value: 8.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg443_6"
                     /sec_met_domain="Radical_SAM (E-value: 9.5e-30, bitscore:
                     94.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLMRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(4819..7047)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg443_7"
                     /sec_met_domain="Gly_radical (E-value: 7.7e-47, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1171.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEVKKEDLRNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             complement(7576..8031)
                     /locus_tag="ctg443_8"
                     /transl_table=11
                     /translation="LRQARKQPGRTNQYFARSATPARLPARRDATHHRFQTQYPRIESI
                     WSGHLLYLLHHDPERETSHLRLHGYGMLRARLREVARRIQTRTRHRSRRNHTRWKILIG
                     LPALRRCLRTGSGSDDWRESVRKIATDRCEEDYRGVGVNVRNKKRLL"
     CDS             complement(8100..9239)
                     /locus_tag="ctg443_9"
                     /transl_table=11
                     /translation="VGALTERDYTNRLLDDLANPDKVVIVQTAPAVRAALGEEFGFPPG
                     TLVTGKMVYALRELGFDYVFDTDFAADLTIMEEGSEILNRLTRYLNGDKSVRLPILTSC
                     CPAWVNFFEHHFPDMLDIPSTARSPQQMFGSIAKSYWAEKMGIPREKLVVVSIMPCLAK
                     KYECARDEFKVNGIPDVDYSISTRELARLIKRANIGFPLVLDSPFDNPMGESTGAGVIF
                     GTTGGVMEAALRSVYEIYTGESLKNVNFEQVRGLNGVRRATINLNGFELKVGIAHGLGN
                     ARHLLEDIRNGHNEYHVIEIMACPGGCIGGGGQPLHHGNSEILYARANALYREDANKPL
                     RKSHENPYIKTLYEEYLGKPLGEISETLLHTHYFNKSMD"
     CDS             9258..9500
                     /locus_tag="ctg443_10"
                     /transl_table=11
                     /translation="LSAIGTFAFRHHPVKGRGYRRVESATDGTERTDCLNIVADTFAAA
                     TENTFIHVAHDGGSDFPLAGRELASIERHFADIKA"
     CDS             complement(9878..11347)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH_4Fe-4S"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg443_11"
                     /sec_met_domain="Fer4_7 (E-value: 1.7e-10, bitscore: 31.7,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 4.3e-11, bitscore: 32.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 9.7e-51, bitscore:
                     161.9, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00033, bitscore: 11.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="NADH_4Fe-4S (E-value: 2.8e-34, bitscore:
                     107.3, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFYRKQLRIALRNCGFIDPENIEEYIAREGYFALADCLLNKQPT
                     DVIDIIKRSGLRGRGGGGFPTGLKWEFANKQQSDVKYVVCNADEGDPGAFMDRSIMEGD
                     PHSIVEAMCVCGYSIGSTKGLVYIRAEYPLAINRLKTAINQAREYGLLGDHILGTDFSF
                     DIEIRYGAGAFVCGEETALIHSMEGKRGEPTLKPPFPAESGYLGKPTNVNNVETLANIP
                     IILTKGADWFATIGTERSKGTKVFALAGKINNVGLIEVPMGTTLREVIYEIGGGIKGGK
                     KFKAVQTGGPSGGCLTEKHLDTPIDFDNLLSAGSMMGSGGMIVMDEDDCMVSVARFYLD
                     FTVEESCGKCTPCRIGNKRLLELLNKITEGKGTEKDLDTLATLGQVIKDTALCGLGQTS
                     PNPVLSTLDNFYDEYMEHVRDKTCRSKQCKSLLTYTISPERCIGCHLCAKNCPADAISG
                     LVRKPHVIAPDKCIKCGMCMARCKFNAILVC"
     CDS             11617..11751
                     /locus_tag="ctg443_12"
                     /transl_table=11
                     /translation="MPYSLYHRRSESEDVAHRMPVRNTFQSPFHYFLRAMKDCALLSS"
     CDS             11947..14715
                     /locus_tag="ctg443_13"
                     /transl_table=11
                     /translation="MRQILLGLCLLCLLNNVSGQENGREIPLPEKMPQEHPRVLTTPDG
                     KQDTWELIKKEKWAKDVFNKLKERTEVYTNLTDAQPAWLLSRLAMSWKSHATELYVKGE
                     TYDHAGGEKAPYPTVRYTGTRGTAATHGRPKLADVVPYDDDENGNVTFCNNALPERPLE
                     SVHPSKTGRNIESLNREILGIACDAAFLYWMTDEEKFAKLAAGVFDTYMTGIYYRNVPI
                     DLNHGHQQTLVGLTSFEVIHEDALHIVVPLYDFLYNYLKTNYPEKMDIYAGAFKKWADN
                     IIANGVPHNNWDLLQARYIMNVGLVLEDNKEYADGKGREYYIDYVLNRSSIRQWSLTRL
                     ADYGFDSTTGIWAECPGYSSVVINDYANFANQFDNNLKYDLVKAMPVLSKAVAATPQYL
                     FPNRMICGFGDTHPSYLNTNFFIRMIQNAQANGKTEQENYFTALLKCLNPEIDNEKGEK
                     NNVRVSVNSFFEDKPLSLNPKVKAGKIEDYVSPLFYAPNVSWLVQRNGMHPRHSLMISL
                     NASEGNHMHANGISMELYGKGYVLGPDAGIGLTLYSGLDYAEYYSQFPSHNTVCVDGIS
                     SYPVMKSNHSFDLLSCFPASAEPGKEFTSVTYSNVYFREPESRADQTRMMSIVTTGSET
                     GYYVDVFRSRKERGGDKMHDYFYHNLGQTMTLTAADGTDLNLQPTEELAFAGAHLYGYS
                     YLYDKKVAATGKDVKATFTIDMKDKGGDDIVMNLWMKGEPDRDVFTALSPMTEGLSRTP
                     GMPYNIKEQPTLTFVVRQHGEAWTRPFVAVYEPSTKKEPSAIQSVSYFDVEETVLKDFA
                     GICVKSKNGRIDHIFSLSDATQTATYQGMKVKADYAVVSNEYAGNRTLFLGNGTQLVAP
                     KVTVHTDQAGNVLLEKKQGKWYILSSVPCTVVINGKKIKSGITSQLTLLPV"
     CDS             14884..15441
                     /locus_tag="ctg443_14"
                     /transl_table=11
                     /translation="MMYVMRNGCRLGAVLSFLLLSCGVHVHAQRVAVKTNALGWLTASP
                     NVEAEFILGRHVSLNMGVAGNPISTDNFKTTFTHFQPEVRYWLNRPMVSHFLGITAFVN
                     NFNMMVKDVYHKGDAYAAGLTYGYAWVLGEHWNIEATAGIGVMRYRQFKYDKGTPKPKT
                     VNDSKTTIAPVKLGVSFVYIIR"
ORIGIN
        1 ataacaaagc ccgggcttga gaaagtctgg gctttgcgca taaaaaaaag gctgtgtcag
       61 cgttttgaca caacctcgtt tttttgagga agaaaaagga aaaggtgagg gtaggtgagg
      121 gtaaatttct aacattcgta ttttttttta gaagaaaata gaagaataga aataagaaat
      181 ataaaaatga aaagttgcaa aagtaccctc accaaccctc acctttttgc gtgcgaagga
      241 gatgaaatct tattcatata gcctgtttga tttcacctgt tccgtatcaa taatgaatac
      301 agtgtatctt ctcccgtttt ttcccttatg aaattcgaag ccgtgtttgg acatcacttt
      361 tcctagttgg gctttggttc cgtgagaata ttgatacccc gtccgttcgc gaatcaattc
      421 cgcaatttca gtgaccgtca gataatgcac cttttcgaaa cgttccggtt tgcggatatg
      481 tgtcaacacc agttcttctt ccggtgagtg gaaaatgaaa tcctcgttgt tctcttcaat
      541 ccgtgagttt tccgactggg tgaaccaata ctgatatccc ggcttgttga gtagatactt
      601 gatttgtgca tacaactgcg cgtagtttat tttgataaat tccatcgagt cgacatgaaa
      661 gcagagaaaa cggcggttac cagtggtgtc gtgaagcact tcctgataat tgcatgtgcc
      721 ggcaaaagaa gccgtgtgag gaaagttctg tgaacgccgc gcgtatggca ggcggatgct
      781 gattactttg cgggtaacca aatccttgaa gatattcagt tcccgtccgt tcatcccttc
      841 aaactcatcc agattgataa gcatcgcctg cgctattttg gccagatcat ccttgttgtt
      901 cgggttgata agaccggtag aaagataggc gcgcaattcg ggcggcagca ggttgttgat
      961 aaacgtagtc tttccaatgt tctgtatttc gctgcaaagc aacaaaacag tgtggttcac
     1021 cacatcatct tgtgtggcgg cagcgcacat tcccaccaga taacgttcca gacattctac
     1081 ccaaaatttc tggtgactag tatgcacgct gttggcaagg ataccgatat aatccgttcc
     1141 gtcccattca ggcagcgagt ctaaatactc gcgaatagga tggtaggtgc tgctgaagtc
     1201 ggagtagatc agattctgaa tcgtcttgac ggtgcacgaa tagcccagtt cgttcatctc
     1261 catccaaatg ctgttttcca tcatttcgtc gagaatatgg aaaggttccg gttgctccgt
     1321 gtccgttttc cttctgcgat attccatgat atgaagcact tcgttgtagc gtgtatcgta
     1381 attttctttg atatgttgct caatctgtaa tattcgcttc tgcgtactat tcagcttgcg
     1441 ggtgtcgaat tcctcgttgt gtccgtaagc actcccgatc agtgcgtcca tttcatccgc
     1501 gggaagatcg gtgaactggc tcttgataaa agctgccgcc tcttcctggg ggacgccgta
     1561 gcgattgtac atacaagcca ggcaatgcag gtagttgttc cggttgccgg tgacgtactt
     1621 ttcggattta ttgtgataat agttcagagt caccattaag gaagcgtgcg aggaatggta
     1681 gttgagtgcc acttgttcgg tgaggggatt gttgtctggt gctgtcgtct ttttcttttt
     1741 gccggatgcc cttttcttct tttgagactt gaagaacatc ggtggctgtt ccacgatgac
     1801 agctgtggca tcgggattga aataaatatc cggatcgtaa gagaacaggc aagtgcggct
     1861 aacatcctgt ccggaagtgt cgacctcaac tccgcagagc tgggcataaa aggaagcgat
     1921 tttgtgataa gcggcatgat ggaaatcttc aatttcctga atcgtttcgg gcaatgtccc
     1981 gtccgtccgg catacacgta ccacgatttt cagtcccatt cctttgggac tgatgaaagc
     2041 gatgcgggtg tgggcacact tttttgccag tgcgaggatg cgtgccaatg cttcctgtgt
     2101 ctgatggtcg atgtctacca cgatgtatcc cagatacttg acgagagttg cgtttgaacg
     2161 tcctccccgg tagttggctg aaaaggtgat ttccggtagt tctattttct tttcgtttgc
     2221 tgctttctcg ccttgttccg cgaagattcg gcgcacgtcc tccactgttt cccggtatgt
     2281 gccgttgctg atggccgata cgatttcttc ttctgtcatt tcggctatga cgcggtaaaa
     2341 gtcttgaaag atggtaaaat gctccatgtt ggtttgttct ttttaatttg cggttgcaaa
     2401 gaaatttgtt tgtaaaataa tagaatggaa cttttcgttt ttttgattaa gttcctaggg
     2461 ttctcccaaa tagcgtatga tcgttgccac ttgccgggga gagagaaggc ggttgcgggc
     2521 acgatagcct tcttgttcga gttcttgcag gagcggaagg ttgtagacaa tccaacgacg
     2581 tagtatttgt aaggctactt tgagacatac gttggggttg taaagatgag ctagttccga
     2641 ctttttataa gtgcggatat gaaacggctg atccggataa tacatggtga atgatatttg
     2701 gtttatgcta taaagttact gaaaattaat ggtttattaa aagaataacg tcgttattat
     2761 tcatagaata tcaggaaact tcgttgggga atccggaggg tgaaaaatgt gttatcttta
     2821 tgtcgttaac aaataaggaa cgcgttcgaa atgtgtgaaa tcttaaaatt attttattat
     2881 ggcaatgaca gtaacttatt cagtagtgcc gcgcaagaat cctgccaaaa aggatgagtc
     2941 ggcaaagtat tacgcgcagg cacaggcttc gggagagttg gattttgaag agttgtgcga
     3001 gggaatcacg agtcggtcta cctgtacgga gacagatgtg cgtgccgcca tttcgggtat
     3061 tctttatgag gcgaagcgtg cgttgaaagc gggaagaata gtccggttgg gtgatttggg
     3121 cagtttgcag atcgggttga acagtgaagg agctgtgtcg gtcaaggagt tttcaagttc
     3181 gctgattacg gctgcccata ttattttccg tcccggaaag acgttggcgg acatcacgaa
     3241 gattcttagc taccagcagg taacgacgcg tgcggtggcc caaacgggcg gtagcggcaa
     3301 tgaaggagaa gacgatgaca aaggttccgg tggcggttca gacggtggtg gaagcggaga
     3361 agctccggat ccggcagcat gataacttta atattagatc aaatgaaaga aattgtaact
     3421 aagattttgg atgtaatcat gttccttgtg cctttcttcg gaaaaagaaa gcggaacaga
     3481 attgtgagag aggtgcgctt caatgctacc cataaggaag tgtgtaatgt gaaaacaacg
     3541 gaaagggaaa aggacgatga gaaagattag tctgattgtg attcactgct ctgctacccg
     3601 tgctgatcgc gacttcacgg cgaaggatgt ggacactgcc catcgctttc ggggcttttc
     3661 ttgttggggg tatcattatt atatccgcaa gtcgggacag atagaaccga tgagggatga
     3721 agatacggtg ggtgctcatg cacgcggttt taatgcgatt agtttagggg tgtgctatga
     3781 aggcgggctg gatgagaacg gaaaggcagc agatacgcgt acttcccgcc agaaagaggc
     3841 gatgcatcgt ctggtaagcg agttgttgca gcgttatccg gatgcaaagg tggtcggtca
     3901 ccgggacttg agccctgaca ccaattataa tggaattgta gacccctggg aacggatcaa
     3961 agagtgtccc tgttttgagg tgattgaaga atttgagagt tgagaatgga gagttgagag
     4021 ttggctgcgc actgttatac tgcatagtta actctcaatt ctcaacttct tcaactaatt
     4081 gaccaccaca gtagtgaaat attctttaaa tacctccgcg gctttttcaa gttgttcggg
     4141 ggtattttct tttacgtctt tcagcttgta ttcctgctcc atcgcttcat acttatgtac
     4201 gcctaatgta tgataaggca ggatttccac tcgttgcacc atcttatatt ttcccagagc
     4261 ctctcctaaa cggcggatgt cttcctcgaa atcgctgtat ccgggcacta atacataacg
     4321 cagccagaaa ggtttctcgt tttcttccag ccatgctgcc gtgcggatgg tttgctcgtt
     4381 acttcttccg gtcagtgcct gatggcgtgc cggattgaac tctttaatat ccagcaatac
     4441 aagatccgtc agtttgaaaa gttcttctac ttcttcgttc cagataccgc cgttgctgtc
     4501 tatgcataca tgtattccct tttctttcag ttcacgcatt aaagggacta gtgctttggc
     4561 ctgaaacgta ggttctcctc cggagaaagt gactcctccg cgtttcccga aaaaaggacg
     4621 ttggctcata gccatgcgga cgatttcttc cggtggggta ggtgtgcctc cttttccggc
     4681 tatcgtgtcg gggttggcac aatacaggca gcggaaattg catccttgaa gaaaaacgac
     4741 gagccgtaag cccggcccgt cgaatgttcc catactttcg tatgaatgta cgtttatcgt
     4801 catattgagt agatctgatt acatacgttc gtggaagcta cggctgataa cttccaattg
     4861 atgttcgcgg ctcaacttca cgaagtttac ggcataaccg gaaacacgga tggtgagttg
     4921 cggatatttt tccggatgtt ccatggcatc gtaaagcatt tcacggttca gtacgttcac
     4981 gttcaggtgg tgagcgcctt tggtgaagta accatccatc attgtcacca gattttctac
     5041 gcgatcttct tcagtagctc ccagtgattt cggaacgata gagaaggtgt tgctgatacc
     5101 gtcctgtgag tcgcggtaac gtaatttcgc tacggaactc aaagaggcga tggcgccgtt
     5161 cttgtcacgt ccgtgcatag ggttggctcc cggagcaaaa gcgacacctt tggcgcggcc
     5221 gtcgggagta gcacctgtct tcttgccata catcacgttg gaagtgatgg tgagcaaaga
     5281 cagagtagga cgggcatttt tgtaaaccgg aagtttcttc aattcttcgc tgaagaaata
     5341 gaccaggtca acacccaggt ggtctacctt gtcgttgtca ttaccgaagc aagggaattc
     5401 gccttgaata tcgaaacctt ctgtcagacc gatgtcgttg cggcgtgcgg ttactttggc
     5461 atatttgatg gccgacagtg aatcgagggc gatagaaagt ccggctacac cgtaagcaag
     5521 gttgatgcgc gggttggtat ctacaagagc catttgggct ttttcgtagt aatacttatc
     5581 atgcatataa tggatgatgt tcatcgcttc gttgtaaaca cgggcgattt ctgtcaatac
     5641 cttcttgtag ttgctcatta cttcttcgaa gttcagtgtg tcgctggtta gtacggggat
     5701 gtttttcacc attaccgtgc cggtgttttc gcaacgtccg ccgttgatgg caagcagcag
     5761 ggctttagcc aggttgcaac gtgcgccgaa gaactggatt tgttttccga tttcctgata
     5821 agatacgcag cacgcgattc cgtagtcgtc agactggcgt acttcacgca tcaggtcgtc
     5881 gttttcatat tggatggaag aagtgtcgat agatactttt gcgcagaatt ctttgaatcc
     5941 ttccggaagt tccgggctcc acaatacagt caggttcggt tccggtgaag ggccgaggtt
     6001 gtagagtgtt tgcaggaagc ggaaagaagt ctttgtcacc tttgtgcgtc cgtcgttgag
     6061 gcgtccaccc aaggattcgg tcacccatgt cgggtcgccg gcaaagatgt cgttgtaaga
     6121 ttgcatacgc aggtggcgca ccatacgcag tttgatgaca aactggtcga tcagctcctg
     6181 tgcgaaagat tctgtgatag ttcctttgct caattcatat tccatataaa tgtcgaggaa
     6241 cgaagagacg ttacccagtg acatggcagc accgtcttgt tcttttacgg cagcaaggta
     6301 agccatgtac acccattgta ctgcttcttg tgcggtgtag gcaggacggc tcaagtcgag
     6361 tccgtagtat tcgcccatta ccttcatgtc cttcaatgcc ttgatttgct ctgccacttc
     6421 ttcgcgcagg cggatgcggg cttcggtcat cggaccggta aggttacgca aatcttcttt
     6481 ttttacctca atcagtcggt cgataccata gagagccata cggcggtagt cgccgatgat
     6541 acgtccgcgg gcatagttgt caggaagtcc ggtgaggaat cccagagaac ggaacgaacg
     6601 gatttcttcg gtatatacgt caaatactcc gtcattgtgc gtcttgcggt agtgagtgaa
     6661 tatatctttt acacggtcgt ccacttccac gccgttttcg tggcaggctt tgctcaccac
     6721 gttgatacct ccgaaaggtt tgatggcacg tttcagaagt tcgtctgttt gcagaccgac
     6781 gatcagttcg ttttctttgt cgatatatcc ggctttatga gaagtgatgg ttgagacggt
     6841 gacattatcc agtgagcgta ctccgttatt ggctctttct tctgccagtg cttcgaggca
     6901 gcggttccat acagcttttg tgcgttcggt aggtccttcg aggaaagaag catctccata
     6961 atacggagtg atgttgtgac taacgaaatc tcttacgttg atttctgtgc tccaaagacc
     7021 gtctttaaag atcttattta attccataaa tgataaaatt agaggttgta gttatccttt
     7081 tctttagagc gcacaaagtt acaacgtttt ttcatataat cagcataaat atgctctatt
     7141 ttatgctttt caacataaaa tacctagata ttgctattct ttggaaatga tgttcgtgat
     7201 tttttttgtg aaaactcttg taggtttaaa atatattcgt acctttgcac cgcttttaac
     7261 gaaaagcact tctgaaaagg aagttttgga gaggtggcag agtggtcgat tgcggcggtc
     7321 ttgaaaaccg ttgtaccgcg aggtacccgg ggttcgaatc cctgtctctc cgctaggaag
     7381 cagctttttg ctgctttctg tttttataga gagttgttct ctagttggta attataagga
     7441 gaggtgctcg agtggttgaa gaggcacgcc tggaaagcgt gtatacccct aaagggtatc
     7501 acgagttcga atctcgttct ctccgctttt ttgtttgttg ttaaaaaaat gtttgaaagc
     7561 ggctgccttg gtttttcaaa gcagccgctt tttattccgg acatttactc caactcctcg
     7621 ataatcttct tcacatctat cggttgcaat cttccgtaca ctttctcgcc aatcatcact
     7681 accggagcca gtccgcaggc acctacgcag cgcaggcagt ccaatgagaa ttttccatct
     7741 ggtgtggttt cgccgacttc gatgcctagt acgcgtttga attcttcgag caacttctcg
     7801 gagccgcgca cgtaacatgc cgtacccatg cagacggaga tgggatgttt ccctttcggg
     7861 gtcatggtga agaaggtata gaaggtgacc actccatata ctttcgatac ggggatattg
     7921 agtttggaag cgatgatgcg ttgcatctct tcgggcaggt agccgtgcag gtgttgcgct
     7981 tcgtgcaaaa tattgattag ttcgcccggg ttgtttccgt gcttgtcgca aatcgttcgg
     8041 acttgttctg ccacatcgca ggctagtttt atatctgaca tattactctt cgtttaaagt
     8101 taatccatag atttgttgaa atagtgcgtg tgcaatagcg tttccgatat ctcgcccagt
     8161 ggtttgccga gatattcctc gtacaaggtc ttgatgtacg gattctcgtg cgatttgcgc
     8221 aaaggcttgt tggcgtcttc gcggtagagt gcgttggcgc gtgcatacaa tatttccgag
     8281 ttgccgtgat gcaatggctg tccgcctcct ccgatgcaac ctccggggca agccataatt
     8341 tcgattacat gatattcgtt gtgcccgttc cgtatatctt ccaatagatg gcgggcgttg
     8401 cctagtccgt gtgcgatgcc tacttttaat tcaaatccgt ttaggttgat ggtagcacgc
     8461 cggacaccgt taagtccgcg tacttgttcg aagtttacat ttttcagaga ttctccggta
     8521 tagatttcat aaacagaacg gagagcagct tccattacac cacctgttgt accgaaaata
     8581 acgccggcac cggtcgactc acccatcggg ttgtcaaacg ggctgtccag taccagcggg
     8641 aagccgatat tggcgcgttt aatcagtcgt gccagttcgc gggtggaaat agaataatct
     8701 acgtcgggaa taccgttcac tttaaattca tcgcgggcac attcatactt ttttgccaga
     8761 cagggcatga tggatacaac taccagcttt tctctgggaa ttcccatctt ttccgcccaa
     8821 taggatttgg cgatagaacc gaacatctgt tgcggtgaac gggcggtgga tggaatgtcc
     8881 agcatatccg ggaagtgatg ttcgaagaag ttcacccatg ccggacagca ggaggtcagg
     8941 ataggtaacc gtacggactt atctccgttg agatagcgcg tcagacggtt tagtatttcc
     9001 gatccttctt ccatgatggt gaggtcggcg gcaaagtcag tatcgaatac atagtcgaat
     9061 cccagttcac gcagggcata aaccattttt ccggttacca gtgtgccggg aggaaaaccg
     9121 aattcttcgc ccagggcagc acgtacggca ggggctgttt gcacaatcac cactttatcc
     9181 gggttggcta agtcgtcgag cagacggttc gtataatcgc gttcggtcag tgcacccacc
     9241 ggacagacag ctacgcattg tccgcaatag gtacattcgc tttccgtcat catccggtca
     9301 aaggcagggg ctatcgtcgt gttgaatccg cgacggatgg caccgagcgc accgactgtc
     9361 tgaacatcgt tgcagacact ttcgcagcgg cgacagaaaa tacatttatc catgttgcgc
     9421 acgatggagg cagtgatttc ccgcttgcgg ggagagagct cgcctccatt gaaaggcatt
     9481 tcgcggatat taaagcgtag cgctaatgtc tgaagttcgc aattgccaca tttggggcag
     9541 gtgagacagt cgttgggatg atccgacagg ataagttcgg ctaccacttt gcgtgcgttc
     9601 atcacacgta gcgtactggt tttcactacc attccttccg tgcaacgggt agcgcaggca
     9661 ggagccagat tgcggcgtcc tataacctcg accacgcaga tgcgacagga agcaggattg
     9721 ttctttatgc aggtgccttt caggtcgatg tgacacaggg tcggtatgtt gatgccgatt
     9781 ttcgtggcgg cttcaaggat ggtacttcct tcggggacgg tgatgaaatg accgtctatc
     9841 tggagtgtga tttgtttatc ttccatagta atcgatttta gcagacaaga atagcgttga
     9901 atttgcagcg tgccatgcac ataccgcact tgatacattt atcgggagca atgacatgtg
     9961 gcttgcgcac cagcccgctg atagcatccg ccggacagtt tttggcgcat agatgacaac
    10021 caatgcaacg ttccggactg atggtatacg ttaatagtga tttacattgc ttggaacgac
    10081 aagtcttatc ccgcacgtgt tccatatatt catcgtagaa gttatccaat gtggataaaa
    10141 caggattcgg agaggtttgt cccagtccgc agagggccgt atctttgatg acttgtccca
    10201 aagtggcaag tgtgtccagg tctttttctg tgccttttcc ttccgtaatc ttgttcagta
    10261 gttccagcag acgtttgttt ccaatgcggc aaggtgtgca tttcccgcag gactcttcca
    10321 ctgtaaaatc cagataaaag cgtgctacgg ataccatgca gtcgtcctca tccatgacaa
    10381 tcatccctcc tgaacccatc atggaaccgg ccgagagaag gttgtcaaag tcaatgggag
    10441 tgtccagatg tttttctgtc agacagccgc ctgacggtcc tcctgtttgt acagctttga
    10501 atttctttcc gcctttgata cctcctccga tttcgtagat tacttcccga agagtagttc
    10561 ccatcggcac ttcgatcagc cctacattat taatctttcc ggcaagagca aacactttgg
    10621 ttcctttgga acgttctgtg ccaatcgttg caaaccagtc ggctcctttg gttagaataa
    10681 tgggaatatt ggcaagtgtt tccacattat ttacattggt tggttttccc agataaccgg
    10741 attcggcagg gaagggaggt ttcagagtcg gctctcctcg ttttccttcc atcgaatgaa
    10801 taagggcagt ttcttctccg cagacaaaag ctccggctcc gtatcgtatt tctatgtcga
    10861 aactgaaatc tgttcctaag atatgatctc ccagtaatcc gtattcgcgt gcctgattga
    10921 tagctgtttt cagtcggttg atagctaacg gatattcggc acggatatat actaatcctt
    10981 tggtggaccc gatggaataa ccgcagacac acatcgcttc tacaatcgaa tgtgggtcgc
    11041 cctccataat ggaacggtcc atgaatgcac cgggatctcc ttcgtcggcg ttacaaacca
    11101 cgtatttgac atccgactgt tgtttgttgg caaattccca tttcagtccc gtcgggaaac
    11161 cgccaccgcc acgtccgcga agtcccgaac gtttgataat atcaataacg tccgtcggct
    11221 gtttgttaag caggcaatcg gccaatgcaa agtatccttc acgggcgata tactcttcaa
    11281 tattttcggg atcgataaaa ccacagttac gcaatgcgat gcggagttgt ttccggtaga
    11341 aatccatgtg cttggagtcg ctgacggtat gttccgtttt aggatctaca tacagcaacc
    11401 gttcgattct tcgtcctccg atgatatgct cgttgatgat ttcttccgca tcttcgggag
    11461 tgacttgggt gtaaaaggta ttatcgggga taattttcac gataggacct ttttcacaga
    11521 agccgaaaca gcctacggtg atgacttcta ctttgtcggt gatttcgttc ttttggatgg
    11581 cttttagaag attgtctgta ataccctggc tggaagatgc cttacagcct gtaccaccgc
    11641 agatcagaat ctgaagatgt tgcgcaccgg atgccagtcc gtaacacttt tcagtcacct
    11701 tttcattact ttcttcgcgc aatgaaagat tgtgctctgc tctcttcctg attgttgcca
    11761 aatcatggat agataaaatt ttcataagta tcagaattgt tagtcggttt ttttgcaaat
    11821 atagttcttt gtttgaataa aagtagcgtt cgggcaaata aaacaggtct taatgaaagt
    11881 aattaggtaa ataattctct atcttcgtat ttaataggta gtaaacctaa aaatgaaata
    11941 taaagtatga gacaaatttt actgggacta tgtcttcttt gcttattgaa taatgtatcc
    12001 ggacaggaaa acggacggga aattccgttg ccggagaaaa tgccgcaaga acatccgaga
    12061 gtgttgacta caccggatgg aaagcaggat acgtgggagc tgattaaaaa agagaaatgg
    12121 gcgaaagacg tattcaataa attgaaggaa cgaaccgaag tatataccaa tctgacggat
    12181 gctcaacccg catggttatt atcccgtctg gccatgtctt ggaaatctca tgcaaccgag
    12241 ctatatgtga aaggtgagac ttacgatcat gccggaggcg aaaaagctcc ttatccgact
    12301 gtccgttata caggaacacg tggaacggct gctactcatg gccgtcccaa actggcagat
    12361 gtagtgcctt atgacgatga cgaaaacgga aatgtgactt tttgcaataa tgcattgccg
    12421 gaacgtcctt tggaaagtgt acatccgtca aaaacgggac ggaatatcga aagtctgaac
    12481 cgggaaattc tgggaatagc ttgtgatgca gctttcctct attggatgac agatgaggaa
    12541 aaattcgcga aactggctgc cggtgtgttt gatacgtata tgactggaat ttattacaga
    12601 aatgttccca ttgacctgaa tcatggtcat caacagacat tggtgggatt gacttctttt
    12661 gaagtgattc acgaagatgc cctgcatatc gttgttccct tgtatgattt tctttataat
    12721 tacctgaaga ccaactatcc ggaaaagatg gacatctatg ccggtgcatt taagaaatgg
    12781 gcggataaca tcattgcgaa tggagtccct cataataact gggatttatt gcaggcacga
    12841 tatatcatga atgtgggact ggtgcttgaa gataataaag agtatgcaga tggaaaagga
    12901 cgtgaatatt atattgatta tgtgttgaac cgttccagta tccgtcaatg gagtctgact
    12961 cgtcttgccg attatggctt tgattcaaca actggtatct gggcagagtg tccgggatat
    13021 agcagtgtgg taatcaacga ttatgctaat tttgccaatc agtttgataa taatttgaaa
    13081 tatgatttgg taaaggctat gcctgtactg tcgaaagcag tggcagccac tccgcaatat
    13141 ctttttccca accggatgat ttgtgggttc ggagatacgc atccaagcta tttgaatacg
    13201 aacttcttta tccgcatgat acagaatgcg caggcaaacg gtaagacgga acaggagaac
    13261 tacttcactg ctttgctgaa atgcttgaat cccgaaattg ataatgaaaa gggagagaag
    13321 aataacgtgc gtgtatctgt caattctttc tttgaagata aaccgttaag tctgaatccg
    13381 aaagtgaaag cagggaagat agaggactat gtttctcctt tattctatgc tcccaatgtg
    13441 tcatggctgg tgcagcggaa cggaatgcat ccgcgtcata gcctgatgat ttctctgaat
    13501 gccagtgagg gaaatcacat gcacgctaac ggcatctcca tggaacttta tggaaaagga
    13561 tatgtgcttg ggccagatgc aggaattggt ctgactttgt atagcggcct ggattatgcc
    13621 gaatattact ctcaatttcc aagtcacaat acagtatgcg tagatggaat atcgagctat
    13681 ccggtaatga aaagcaatca ttcttttgac ttgctttcct gttttcctgc ttcggcagaa
    13741 ccgggaaagg agtttacttc tgtgacttac agcaatgtct attttcgtga accggaaagc
    13801 agggcggatc agacccgaat gatgagcatt gttaccactg gctccgagac aggatattat
    13861 gtggatgtat tccggagccg gaaagagcgt ggaggggata agatgcatga ttatttctat
    13921 cataatctcg gacagaccat gacattgaca gcagctgatg gtacagacct gaatcttcaa
    13981 ccgacagaag aactcgcttt tgctggagcg catctgtatg gttattctta tttatatgac
    14041 aagaaagtag cggctaccgg taaagatgta aaagcgacct ttaccatcga catgaaagat
    14101 aaaggtgggg atgatatagt aatgaatctc tggatgaaag gggaaccgga tcgtgacgtt
    14161 ttcacggcct tgtcaccgat gaccgaaggt ttaagtcgta cacctggtat gccatataat
    14221 ataaaagaac aaccgacatt gactttcgtg gtccgtcagc atggagaagc gtggactcgt
    14281 ccttttgtcg cagtctatga accaagtacg aagaaagaac cgtctgccat tcagtctgta
    14341 tcctattttg atgtggaaga aactgttttg aaagactttg ccggtatctg tgtgaaaagc
    14401 aaaaatgggc gtatagatca tattttctcc ttgtctgatg ctacgcagac cgccacttat
    14461 caaggaatga aagtaaaagc agactatgca gttgtcagca atgaatatgc aggaaaccgg
    14521 actttattcc tggggaacgg aacacaactt gttgcaccca aggtgaccgt tcatacggat
    14581 caggcgggca atgtgttact cgaaaagaaa cagggaaaat ggtatatcct ttcttctgtt
    14641 ccttgtacgg tggttattaa tggaaagaag ataaaatcag gaataacatc gcaactcacg
    14701 ttattgcctg tctgattaaa atgattttga atgaaaaaaa tgcaataaaa aaacgtattc
    14761 aaacgtttta aatgccatat tttttctaaa tttgcggctt tctgtctgat gtttaaggga
    14821 aacagacaga aagccctttt tatgggtaag tattagtggg aaatatttag tgggaaataa
    14881 attatgatgt atgtaatgcg gaatggttgc aggctagggg ctgtgctatc atttctgtta
    14941 ttatcttgcg gtgtacatgt acatgcgcaa cgagtagcag tcaaaacaaa cgcattggga
    15001 tggctgacag ccagtccgaa tgtcgaagcg gagtttattt tgggtcgcca tgtctcctta
    15061 aatatgggag tagcagggaa tccaatcagt acagacaatt ttaaaacgac tttcacgcat
    15121 tttcagccgg aagtacgtta ttggctaaat cgtccgatgg tgagccattt tctcggcatc
    15181 accgctttcg tgaataattt taatatgatg gtaaaggatg tgtatcacaa aggggatgca
    15241 tatgctgccg gtttgaccta tggatatgca tgggttctcg gagagcactg gaacatcgag
    15301 gcaacagccg gaataggtgt gatgcgttac cgtcagttta agtatgataa gggtactcca
    15361 aaaccgaaaa ctgtcaatga tagcaagact actattgcgc ctgttaaact gggagtgtcc
    15421 tttgtttata ttatccgatg aatagaacga atattagtta gccaaaaaag aatgaaaatc
    15481 aatttaaaac atgatagatt aataggaata cttctcatgg caatgctggc atcttgtata
    15541 agtgtatccg cgcaacgtat ccgcgtacag ggacacatca caaatccaca aggcaagagt
    15601 attccgaatg taaatgtgtt gaatcctgca aatgatgaac gcatagaaat gtccgacgaa
    15661 gatggtcgat acagtgtatt ggtagataaa aacggttcat tgaagtttac gtgcgtcggt
    15721 tatgaggata agacggtgaa agtggatgga aaacagattc tcaatgtcat attgagagat
    15781 gctgtgatcg aattggatga agtaacgatt acttcgaaga taaaagataa agtggttccc
    15841 gaacctacgg acattgaaat caaaggaaac tatttccatc tgaaaacccg tgtcccggtg
    15901 ccgaaggaaa tgtttaattc gcatcgtcgc ctggtattgc aaccttccat ttatgatgtg
    15961 acattaaaga aacggctgtt gatgcgtcct gtggttttcg acggaggcac gtataataca
    16021 acacaacgcc ggatgtacga ttatgagatt gaagaagatc ctttgcatga atatattcag
    16081 gtaaaaacga cttcttcccg taaaggagac atcatagctt accatgattc gatttatata
    16141 gagtacctgc aacatgatta ccgggcggat gtgcatcttg ccatggagaa ttatcggaat
    16201 ataatttatc gtgattcttt ctctattgca cgggggacag tcaatccgct tcgtttcttg
    16261 gaatataaat tctccgcttt caagctgacg gatgagaaat accttccgaa acctgtgatg
    16321 cagttgaggg acactaaagg agaagtgaat ctgacattcg ttgtaggtaa agccaatctg
    16381 gatgataaaa atccacggaa tcaagtggaa ctgaatcgtt tgaatcagga attgcgtagc
    16441 attgaaacga atccggatgc ttctttaaag agtttccata taacgggtgt tgcttcaccg
    16501 gacggttctt atgaatcgaa tttaaaactg gccaaattac gtacggataa agcattggaa
    16561 cgtatcttgt cgcaattaga tcccggaaca cgtaaacttc tggaagtaaa atctgatgca
    16621 tcggttgctt cctggaaaga agtggtagga ttactgaaaa aggactctaa acatgacttg
    16681 gctaaaagtg tggaagagct aatcaaacaa tacgaggcta ctccgtaccg attgaatcat
    16741 gcgttaaaaa cgaaacattt ctataaagag atagccgaag tgtatctgcc taaattaaga
    16801 aaagtgcaat acacatacgg atattccatt ttccgttctc tgacggacga ggaaatcaga
    16861 caactctata agaggcatcc gaaagatctg acccgatttg agttttaccg tatgattgca
    16921 accgcaaagg atctgaatga aaaagaaaaa tattgcagag aagcacttga actctatgat
    16981 aactttacgt atgcagccaa tgaactggcg gtagcaacta tacagagaga ggctccggat
    17041 tcgagaa
//
