LOCUS       gnlProkkaONGKLIMM_37   15119 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ONGKLIMM_37.
ACCESSION   gnlProkkaONGKLIMM_37
VERSION     gnlProkkaONGKLIMM_37
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 23:00:10
            Original ID  :: gnl|Prokka|ONGKLIMM_37
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15119
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15119
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[14657:15119]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14658..15119
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..15119
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15119
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             complement(2..172)
                     /locus_tag="ctg37_1"
                     /transl_table=11
                     /translation="MKKTITTLLLLSCITAFSFAQSIVMTSGTIDFIKDQQVIQFTFSY
                     DEMLVGKLTESE"
     CDS             complement(230..970)
                     /locus_tag="ctg37_2"
                     /transl_table=11
                     /translation="MRKLLLLLTLLLSISTYVAAQNYTEVVYLKNGSIIKGVIIEQVPN
                     VSLKIKTSDGSLIICQMSDVEKITKEERYTRDYRKEANNRKAARNTLKGYKGFVDFAYI
                     GDVSDYNASKIELSTSHGYQFNNYFFVGGGVALNYYTDADLVAAPIYANFRANFINKRV
                     TPFADVKTGYAVGDIEGAYASIGVGVRFSLKGKKALNLALMYNFQDYDTTTDYSYSYGG
                     HYYHDSWDDTWELHGVGVRFGFEF"
     CDS             complement(990..1559)
                     /locus_tag="ctg37_3"
                     /transl_table=11
                     /translation="MKKLILFLFLSTSLFCFGQGKSALKDIQSIKFYGVDYSQAKVFGA
                     DESPIQFKDAFRRINELFITEAKKYNVGKQLKKEVTEISLDAVNQVNENINLAELMTTK
                     REYSLSKEQIKAAIEALPIQKTPGVGMVFIAQFLDKSNNRGTYEVVFFNTETKEIIEEW
                     ITDGKARGFGLRNYWAGSVYSALKKL"
     CDS             complement(1617..2912)
                     /NRPS_PKS="Domain: AMP-binding (55-290). E-value: 4.5e-14.
                     Score: 43.6. Matches aSDomain:
                     nrpspksdomains_ctg37_4_AMP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_4"
                     /sec_met_domain="AMP-binding (E-value: 3e-11, bitscore:
                     32.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNPEIQFRSPEEIKCYQEERLTQTLTYLQAHSKFYQRMFEEHH
                     IDINQIKKIEDLQQIPVTTKTDLQLHNDDFICVDKEQIIDYVTTSGTLGDPVTFVLTSE
                     DLDRLSYNEYLSFTTTGCSKKDILQLMTTIDRRFMAGLAYYMGARELGMGVIRVGNGIP
                     ELQWDTIRRIHPTCGMVVPSFLIKLIEFAEKNHIDHNACSMQKCICIGEALRNQEFQLN
                     TLGQKIHDKWPALQLYSTYASTEMQSSFTECSEFHGGHLQPELIIVEFLDDNNRPVAEG
                     EAGEVTITTLGVEGMPLLRFKTGDICYHHTEPCACGRNTIRLSSILGRKGQMIKYKGTT
                     LYPPALFDILDNIPSVKNYIIEVYTNELGTDEILIRIGSENRSEGFAKEIKDLFRSKVR
                     VAPSINFESAEYIAKIQMPPMSRKTIKFIDLR"
     aSDomain        complement(2043..2747)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg37_4_AMP-binding.1"
                     /evalue="4.50E-14"
                     /label="ctg37_4_AMP-binding.1"
                     /locus_tag="ctg37_4"
                     /protein_end="290"
                     /protein_start="55"
                     /score="43.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DLQQIPVTTKTDLQLHNDDFICVDKEQIIDYVTTSGTLGDPVTFV
                     LTSEDLDRLSYNEYLSFTTTGCSKKDILQLMTTIDRRFMAGLAYYMGARELGMGVIRVG
                     NGIPELQWDTIRRIHPTCGMVVPSFLIKLIEFAEKNHIDHNACSMQKCICIGEALRNQE
                     FQLNTLGQKIHDKWPALQLYSTYASTEMQSSFTECSEFHGGHLQPELIIVEFLDDNNRP
                     VAEGEAGEVTITT"
     CDS             complement(2896..4632)
                     /locus_tag="ctg37_5"
                     /transl_table=11
                     /translation="MHKTIKKIFKYTSCVLLSLLVILIAGICYLYFSADMRTPKHEPSI
                     IMTKVSHADTTTMVPAEVLYNDTLDLRYYDGNFLRHSESGLWELFVKGDAFQRGEAIGK
                     LSSDLLHYQEKVFVDQIREIVPSDSYLKFLRFLIVLFNRHLGENVLEEYRDEIYGISLS
                     CTHEYDFIGTPYERQLNYHSAHDLGHAMQDYMLVGCSSFATWGTQSADSSLLIGRNFDF
                     YVGDAFAENKQVAFYTPDQGYKFASVGWPGMIGVLSGMNETGLTVTINAAKSAVPTGSA
                     TPISILTREILQYASTIDEAFAIAQKRKTFVSESILIGSSKDGKAAIIEKSPEKTVLFK
                     GKEANRLICTNHYQSEEFSKDERNMENIRTSDSPYRFARLEELINENMPIDASKAASIL
                     RNHKGLQDADLGLANEMAINQFIAHHSVIFQPEKRLMWVSTSPWQCGKYVAYDLNKIFN
                     DTINLQHEIYSSNLTIPADEFTETPEFQHLLTYKKLTPLLLKKIRKKEKIEEHVLKTYE
                     ASNPSLYYVYEVMGDYYEAMQQPQQAIVYWQKALKKPIPKLQEKERIQQKIQKQSKDGK
                     ES"
     CDS             complement(4625..6115)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 159.6; E-value: 2.3e-48)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_6"
                     /sec_met_domain="DAO (E-value: 6.7e-10, bitscore: 28.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYDIIIIGSGLGGLECGAILSKEGFNVCVVEKNTQFGGCFQTY
                     RRKGHLFDTGIHYVGSLDEGQVMNQYFRYFGIMDKLKLKRLDDEAFDTIYYKGKTYDYA
                     MGYPQFIETICRSFPHEKENLKRYAEQLQTVGNLISVDHLKQGTLALEGMKYFCTSAAG
                     LIADITPDPTLQNVLAGSALLYGGLKDVSTFYEHAMINHSYIEGAYRFVDGSMQVSLEL
                     INVIRANGGTVLNNSEATRIIVENEKVQGVIINGEERLESDYVISNMHPQRTLEILDKN
                     RSIKNAYISRIRSLENTYGIFTLYLVMKKKSTPYQNRNLYLHGDHKVWYDKQLYPGRTT
                     NCMISMQASSEDSQYASVISILTPMYMDELSAWKDTTPEHRGESYRSFKKEKTEQLLRF
                     IRSHGIDFSDNIEEIHTTTPLSYRDYTGTVDGSAYGIIKDYKCPQIGFVSTRSRLGNLF
                     LTGQNLNVHGALGVTLTSMLTCAEFVGQEYLAKKVGNA"
     CDS             complement(6108..9974)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:MMPL domain-containing transport protein (Score:
                     45.7; E-value: 4.5e-14)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_7"
                     /transl_table=11
                     /translation="MTQFFIGLYDYFERHKILFYLSLISCVLLMGFFALQVRFEENITQ
                     FFPDTKDSQNTIKVFDNLKIKDKIIIMLSSADTCHQVEPDSLIEAAGQLQQTLTEKAGG
                     TLIKGIFAQVDQSLIGGATDFVYEHLPLFLTDTDYQRFDSLLTEKGIQAIMQKNYTNLL
                     SPAGIALRSYILRDPLGLGSEALKHLQDFQLEANYEIYDEHIFSKDGSTLLMFITPVFS
                     TGSTGKNDELIKILEEELQHVQGESPTIRVEYFGGPSVGVYNARQIKKDTILTSSLALL
                     IIIVFISLVFKRKRSIPLIITPVLFGGLFALFLIFFIKGSISAIAVGAGSAVMGIALSY
                     SIHMLAHQNHVSTVQQLIKEIAYPLTVGSFTTIGAFMGLIFTSSDLLRDFGLFASLALV
                     GTTLFCLIYLPHFLKGQADVKQGCILRIIEKINAYSYEKNKWLVGGILLITVICLFTSQ
                     KVGFNNDMMSLNYEPQHLKQSEEKLMQLFDSDEKTVLFVSVGKDMNQATETYAMTNQKL
                     LALKDQGLIKDYASASQFLISPQEQQLRLKKWKDYWTDEKQQQIREQLETAAAEYRFRP
                     GSFDPFYQWLNQPFGEYHYTAQEDDLSGKLLNEWQTSADSITMLISQIRISDQNKETVY
                     QHFSKDQDVVIFDRSYFANKWVSAINDDFYLILYISSFLIFFALWFSYGRIELTLMSFL
                     PMLVSWVIILGLMGILGIEFNIINIILSTFIFGIGDDFSIFIMDGLQNKYRTGQKVLNS
                     HKTAIFFSAFTTVVGMGALVFAKHPALQSISLISILGMIAVVLVAYTIQPLIFRFFIAG
                     PASKGLPPYTLIGLIRTVLLFLLFFIGCIFLRVLIAVLYLVPVRKSSKQRLVCRLIQIT
                     CKGILLLATAVKKEHINKANERFQHPAIIIANHQSFIDILVLLSLSSKILMVTNHWVWH
                     SPFFGAIIRYVDFYYIGEGYEQYMERMRKKVKEGYSIAIFPEGTRTYNGKMKRFHKGAF
                     YLAETLQLDILPILLYGNNKIIAKAQPFNIRKGIIYTEILPRIPGDDLSFGTTYQERTK
                     RISAYMKEGYARICREKNTTDNPAFYEALIQNYIYKGPVVEWYIRIKVKMERNYRLFNR
                     LIPVQGQITDIGCGYGPLCYMLSLLSEDREILGIDYDEDKIALAQHGWLRNEHLQFRHG
                     NALEYPLPESDVFILNDMLHYMSYEHQRTLLLKCADRLRSQGMIIIRDGNSANTSKHRL
                     TRFTELLSTRIFNFNRTAGELHFTTETQLREIAVTCGMNVEIIPNDKYTSNTIYIFRKP
                     NEHE"
     CDS             complement(9971..11161)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 83.5; E-value: 3e-25)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_8"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8.6e-30,
                     bitscore: 93.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEQISTAYWHEKLKQLGIIVIIPSYNNGKTLAEVIASVRLYAPE
                     ILVVNDGSTDETPEILNQEANLHIITHPVNQGKGVALKHGLSFAKKQGFRYAITIDSDG
                     QHFASDIPVLIEAIEKEPDTLLVGSRNLTSDNMPGKNTFANKFSNFWFTLETGIKLQDT
                     QSGYRLYPIQRMNVDKWYYTAKYEFELEALVFAAWGGNPVKNIPVHVYYPPQEERVSHF
                     RPFRDFTRISILNTVLVLVTFLWIVPRNFFRKLTWKNCKQFFSNHITHSPESNLRITAA
                     IMLGVFMGIVPAWGYQMLITLFLAHLFRLNKVIAIVAANISIPPMIPFLLYGSYVTGCK
                     VLGEPVNLHLNELSFENVKSVIEQYLIGSVIFAVVCSILAGTIAFILLTACRKKKI"
     CDS             complement(11158..11637)
                     /locus_tag="ctg37_9"
                     /transl_table=11
                     /translation="MLLDNFYTILSSESSDSTTWTIQIELNPDHTVYQGHFPEHPVVPG
                     VCLLQLIKECAENIRQQKLQIVQVSSCKFLSAINPIETPRIAIVLILKETEEGKFQLQA
                     EGTIKGNTVNKSIVKEDIAKEEIVKENTGKESIIKEENIKDECFIKLKAALTPKA"
     CDS             complement(11641..12201)
                     /locus_tag="ctg37_10"
                     /transl_table=11
                     /translation="MRRSLRFVSLTVLLFLGIQVQTSCSPRISGEGSTVPPVIELTQGE
                     ESQKYNIQLDFMKHHMSGMLIVRRMPDNEIRIVASTYFGLSLFDFSLHDDQFNVNSCIE
                     PMKKEKVLKLLEMDFRRLFLNGKDVRVKATKDNATQKRTSGKGFGKSVVYITGDTPGEP
                     AQIKIKHPWIRLTIRLDKLSKEI"
     CDS             complement(12176..12811)
                     /locus_tag="ctg37_11"
                     /transl_table=11
                     /translation="MRTLLLYLSLFFLSIATVHAQSMKKMVQKTEFENRLAKEAQTVKS
                     IESDFTQVKYLDVFDEKVTSKGKFYYQKSNKICMEYFRPMDYLIVINGSKLKIVSDGKK
                     SIMNLSSNKMMAQMQDMLTACMIGDLSKMSSNYQLEYFEDARYYLVKIKPTNKAVQAYI
                     AGIEIYLDKKDMSVHKLRLSETATNYTEYEFYNKKFNSLKNETKFAIR"
     CDS             complement(12823..13503)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235:polysaccharide deacetylase (Score: 125.9;
                     E-value: 3.4e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_12"
                     /transl_table=11
                     /translation="MMIVCLLLCLFLILSFLVYASYSIQSGIYLRSFCKKRTTEKVVAL
                     TFDDGPDPIQTPKVLKVLKEYQATACFFCIGHKIKGNEALLKSMVTEGHLIGNHSYSHS
                     GLFPLYGLSKMKKDLQTCQCELERVTSQPVTLFRPPFGVTNPTIAKAVRQLGYTSIGWS
                     IRTLDTQQSAPDKILARIRKRLEPGAIILLHDRMPGSDQLVKQILDLLKEQGYTVVRPD
                     KLLA"
     CDS             complement(13500..14645)
                     /locus_tag="ctg37_13"
                     /transl_table=11
                     /translation="MQPVYIQRIASIHPQGNHSQENNPKVNDSLDVAANRPFLQACEPD
                     YKDIIANATLRRRMSRIVKMGVACGLECMGELSPEKIGGIITATGLGCLVDTEKFLNNL
                     LDNEERMLNPTPFIQSTFNTIGAQIALIHQIHAYNMTYVHRGLSFESALLDAMMKIEEG
                     SENILVGAMDEMTETSYIIQQRLGLLKGIEAGEGAQFFLLSREAGEHPLAEIRGLETFT
                     GQHTTEEISSRIIRFLQRNGLECQGIQWLVTGKNKKQSLQGDYHEQITGYKKSTINEGK
                     STNQRSIINGESIINEKDIIIKEIMMNESNSIYEELETNLFPESIHLSFKDECGEYPTA
                     SSYAVWKAVKTSINCTTPTNILIYNHHHSINHSLILIRKSV"
     CDS             complement(14658..15119)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_14"
                     /sec_met_domain="APE_KS2 (E-value: 1.9e-45, bitscore:
                     145.4, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAFLSMSEAIASSGISPEDIDYINVHGTGTPGNDASEGMALRRI
                     FGEHVPPFSSVKAFIGHTLGASEGIEAVYSVLSIDKGMIYPNLNFTEPMPETELLSETG
                     VKSETGLIPETSFQEGVPIRHVLSNSFGFGGNDSSLLFSATNFPKRTNL"
ORIGIN
        1 attcgctttc tgtcagtttt cctaccagca tttcatcata agagaaagtg aattgtatca
       61 cttgttggtc cttgatgaag tcgatagttc ctgaagtcat aacaatgctt tgcgcaaatg
      121 aaaatgcagt aatgcagctc aatagtagaa gtgttgtgat agtctttttc atggttcgaa
      181 tttgatttat tgtttgtttg ttgttaaaag gtacagacaa acagtagatt tagaattcaa
      241 aaccgaacct gactcctact ccgtgtaact cccatgtatc atcccagctg tcatgataat
      301 aatgacctcc ataactgtaa ctataatcag ttgtggtgtc ataatcttgg aagttgtaca
      361 tcaaagctaa attcaaggcc tttttccctt ttaaagaaaa acgtactcct actcctatcg
      421 aagcatacgc tccttctatg tctcctacag catatccggt ttttacatct gcaaaaggcg
      481 tcactctttt gttgatgaag ttagccctga agttagcata gattggtgca gcaacaagat
      541 cagcatccgt atagtagttg agagcaacac caccaccaac gaagaaataa ttattgaatt
      601 gataaccgtg tgaggttgat aattcaattt tggaggcatt gtagtcgctg acatcaccga
      661 tgtatgcaaa gtccacgaaa cctttatagc cttttaatgt atttcttgca gctttgcggt
      721 tgttggcctc tttgcggtaa tctcttgtat accgttcttc tttagtgatt ttctccacat
      781 cactcatctg acagatgatg aggctgccat cacttgtttt aatttttaag gaaacattgg
      841 gcacttgctc aatgataact cctttgataa tgctgccatt ctttaaatac actacttctg
      901 tgtaattttg tgctgcgaca taagtactga tacttaacag taaagtcagc aataatagta
      961 gttttctcat gtttatatat attattggtt tataatttct tgagtgcgct ataaacagat
     1021 cctgcccagt agttgcgcaa tccgaaacca cgtgcttttc catctgttat ccattcttca
     1081 atgatctcct ttgtttcagt attgaagaat acgacttcat acgtacctct gttgtttgat
     1141 ttgtccagga actgtgcgat aaataccata cctacgcccg gcgttttctg aataggtaat
     1201 gcttcgatag ccgctttgat ttgttcttta ctaaggctat attctctttt ggtagtcatc
     1261 agctcggcca agttaatgtt ttcgttcact tgattgactg catccaatga gatttccgtt
     1321 acctcttttt tcaactgttt tcctacgtta tacttttttg cttctgtgat aaacagctca
     1381 ttgatacgtc tgaaagcatc tttgaattgt atcggtgatt catctgcacc gaaaacttta
     1441 gcttgggagt agtccactcc atagaacttg atagactgga tgtctttcaa tgcactcttg
     1501 ccttgtccaa aacagaacag gctcgtactt aagaataaga atagaataag ttttttcata
     1561 tacgttaatg ttaaagtgat atagttggtt tactaacttc caaaagtaga aaataattat
     1621 cgtaaatcaa tgaattttat cgtttttcga ctcattggag gcatttgaat ttttgcgatg
     1681 tattctgccg actcaaaatt aatgcttgga gccactctta ctttcgaacg aaacaggtct
     1741 tttatctcct tggcaaaacc ttcgctgcgg ttttcacttc cgatacggat cagaatttca
     1801 tccgttccca attcgttggt gtagacttca atgatgtaat tctttaccga agggatattg
     1861 tccagtatgt cgaacagtgc gggtggatac aaagtagtcc ctttgtattt aatcatttgc
     1921 ccttttcgtc cgaggatgga actaaggcga atcgtatttc ttccgcaggc acaaggttcg
     1981 gtatgatggt aacaaatatc acctgtcttg aagcggagca gcggcatacc ttctactcca
     2041 agcgtcgtga tcgtcacttc gccagcttct ccctctgcga caggacgatt gttgtcatcc
     2101 aaaaactcta cgatgataag ttccggttgc aaatgcccgc catggaattc gctacattcg
     2161 gtaaaggacg actgcatttc ggtggaagca taggtggaat atagctgtaa ggcaggccat
     2221 ttgtcatgta tcttctgtcc gagcgtattt aactgaaact cctgattgcg caaagcctca
     2281 ccgatacaga tacatttctg catcgagcac gcattatggt caatatgatt cttctcggca
     2341 aattctatca gtttgataag gaaagaagga acgaccattc cacaagtcgg atgaatccgg
     2401 cgaatcgtgt cccattgcag ttcggggatg ccgttaccta cccggatcac tcccatgccg
     2461 agttcgcgtg ctcccatata ataggcaagt ccggccatga agcggcggtc gatggtagtc
     2521 atgagttgca gaatatcctt tttactgcat ccggtggtgg tgaaagacag gtactcgttg
     2581 taagataaac ggtccaggtc ctcggaagtg agaacgaaag tcaccggatc tcccagtgtg
     2641 ccggaagttg ttacatagtc gatgatttgc tccttgtcta cacagatgaa gtcgtcgtta
     2701 tgaagttgca agtctgtctt ggtggtgaca gggatttgtt gcaagtcttc aatcttcttt
     2761 atctgattga tgtcaatgtg gtgttcttcg aacattcgtt ggtagaactt ggagtgtgct
     2821 tgcaggtagg tcaacgtttg ggttaaccgt tcttcctgat agcatttgat ctcttccggt
     2881 gagcggaact gaatttcagg attcttttcc atctttggat tgtttttgaa ttttctgttg
     2941 gatacgttct ttctcttgca acttgggaat cggtttcttt aatgcttttt gccagtatac
     3001 gatggcttgt tgcggttgct gcatagcctc gtaataatct cccatcactt catatacata
     3061 atatagagaa ggattagagg cttcgtatgt ttttaaaaca tgctcttcta tcttctcctt
     3121 tttcctgatt ttcttcaata ggagcggagt caacttctta taggtaagaa gatgctggaa
     3181 ctccggtgtt tcggtgaatt catctgccgg aatggtcagg ttggaactgt atatttcgtg
     3241 ttgcaagtta atcgtgtcgt taaatatctt attcaggtca taagctacat actttccaca
     3301 ttgccaggga gaggtagata cccacatcaa tcgtttctcc ggttggaaga taacggaatg
     3361 atgagcaata aattgattga tagccatttc gttagccagt cccaagtccg catcttgcaa
     3421 acctttgtgg ttgcgcagga tagaggcggc cttggaggcg tctatcggca tattttcatt
     3481 gatgagttct tccagtcgtg caaaacggta tggactgtcc gaagtacgga tattttccat
     3541 gtttcgttca tccttgctga attcctccga ttggtaatga ttggtgcaga tgagccggtt
     3601 ggcttctttt cctttaaaga gcactgtctt ctccggggat ttctcaatga tagcggcttt
     3661 gccatctttg gaagaaccta tcaagatgga ttcggagacg aatgtcttcc gtttctgtgc
     3721 gatggcaaaa gcctcatcaa tcgttgacgc atattgcagg atttctctgg tcagaatgga
     3781 aataggagtg gcggaacctg ttggaacagc agacttggcg gcattgatcg tgacggtcag
     3841 ccccgtttcg ttcatgccgg atagtacgcc tatcataccg ggccatccta cggaagcgaa
     3901 tttataacct tgatccggtg tataaaaagc tacttgttta ttttctgcga aggcatctcc
     3961 cacatagaaa tcgaagttgc gtccgatcag tagagacgaa tcggcgcttt gtgttcccca
     4021 agtggcaaac gaactgcatc ccactaacat ataatcttgc atggcatgtc ccaggtcgtg
     4081 tgccgaatgg taattcagct gacgttcgta aggagtgccg ataaagtcgt attcatgggt
     4141 acacgatagc gagattccgt agatctcgtc gcggtattct tcgaggacgt tctcacccaa
     4201 atgacggttg aataaaacga tgaggaaccg gagaaacttc agataactgt ctgaaggaac
     4261 aatctcacga atctgatcga caaatacttt ctcctgataa tgaagcaaat cggaagacag
     4321 tttgccgatg gcttctcccc tttgaaaggc atcccctttc acaaacaact cccacaatcc
     4381 gctttcgctg tggcgcagga agttgccgtc ataatatcgg agatcgagcg tatcgttgta
     4441 gagcacctct gccggaacca tggtggtagt atctgcatga gacacttttg tcatgatgat
     4501 actgggttca tgtttcggtg tccgcatatc cgctgaaaag tagagataac agattccggc
     4561 tatcaatatc acaaggagcg acaaaagaac gcagctcgtg tacttgaata tctttttgat
     4621 tgttttatgc atttcctact tttttagcca agtattcttg tcccacaaat tccgcacaag
     4681 tgagcatgga agtcagcgtt actcccagtg cgccgtgcac attcaggttt tgacctgtga
     4741 gaaagagatt acccaaccgg cttcgtgtag acacaaaacc gatttgcgga catttataat
     4801 ctttgataat tccgtatgct gaaccgtcca ccgttccggt atagtcgcga tagctcaacg
     4861 gagtggtggt gtgaatctct tctatgttgt cggagaaatc aatgccatgg ctccggataa
     4921 agcgaagcag ctgttccgtc ttttccttct tgaaggaccg gtagctttct ccccgatgtt
     4981 cgggagtggt gtctttccat gcagagagtt cgtccatata catcggtgtc aggatagaaa
     5041 taacactggc gtattgactg tcttcggaag aggcttgcat cgaaatcatg cagttggtgg
     5101 tccgtcccgg atagagctgc ttgtcatacc acactttgtg atctccatgc agatagaggt
     5161 tacggttttg gtacggagtg ctcttctttt tcattaccag ataaagcgtg aagatgccgt
     5221 atgtgttttc gagcgaacgg atgcgggata tgtaggcgtt cttgatacta cggtttttat
     5281 ccagtatctc cagggttcgt tgagggtgca tgttggaaat tacatagtcg ctttccaacc
     5341 gctcttcgcc gttgatgatg actccctgta ctttttcgtt ttcaacaatg atgcgggtgg
     5401 cttcgctgtt gttaagtact gtccctccat tcgcccggat cacgttaatc aattccaggc
     5461 tgacttgcat actgccgtcc acaaaacgat aagctccttc gatgtaggaa tggttaatca
     5521 tggcatgttc gtagaaggtg gagacatctt tcaagcctcc gtagagcaag gccgagcctg
     5581 ccagtacatt ttgtaaagta gggtccggag taatatccgc aatcagtcct gcggcggagg
     5641 tgcagaagta tttcattcct tccagggcaa gtgtgccctg tttcagatgg tctacgctaa
     5701 tcaagttacc aacagtctga agctgttcgg cataacgttt caggttttct ttttcgtgcg
     5761 ggaaggaccg gcagatcgtt tcgatgaatt gcggataccc cattgcataa tcgtatgttt
     5821 ttcctttata gtagattgta tcgaaagcct catcgtccaa acgtttcagc tttagtttgt
     5881 ccatgatgcc gaaatagcgg aaatactgat tcatcacttg accttcatcc aggcttccta
     5941 cataatgaat gcctgtatcg aataagtgtc cttttcgccg gtaggtttga aagcatccgc
     6001 cgaattgcgt gtttttctct acgacgcata cattgaatcc ttctttacta agaatcgctc
     6061 cacattccag tccgccaagg ccgcttccga taatgatgat atcgtattta ctcatgttcg
     6121 ttcggttttc tgaatatata aatagtgttc gaggtatatt tgtcattagg aatgatttct
     6181 acattcattc cgcaggtgac tgctatttcc cgtagttggg tttctgtagt gaaatgcaat
     6241 tctccggcag tccggttgaa attgaagatg cgggtggata gcaattccgt gaaccgggtc
     6301 agccggtgtt tggatgtatt tgccgagttt ccgtcgcgta tgataatcat tccctgcgaa
     6361 cgcagccggt cagcgcattt caacagcaaa gtccgttgat gttcatagct catatagtga
     6421 agcatatcgt tcaggataaa gacatcgctt tccggtagcg gatattccaa tgcgttgccg
     6481 tgcctgaact ggagatgttc gttgcgtaac catccgtgtt gtgccaaggc tattttatcc
     6541 tcatcgtaat caattcctaa aatttcccgg tcttcggaaa gcagagacag catataacag
     6601 agcggaccgt agccgcagcc gatgtctgta atttgccctt ggacgggaat caatcggttg
     6661 aacagccgat agtttctttc catcttcacc ttgatacgga tataccattc tacgaccggt
     6721 cctttgtata tatagttttg gatcagagct tcgtagaaag caggattgtc cgtcgtgttc
     6781 ttttcccggc agatacgggc gtaaccttcc ttcatatacg cggatatgcg tttggtgcgt
     6841 tcctggtagg tggttccgaa agaaaggtcg tcgcccggta tacggggaag tatttccgtg
     6901 tagatgattc ctttgcggat attgaaaggc tgtgcctttg caatgatttt gttgttgccg
     6961 tagaggagga tcggaagaat atccagttgc aatgtttctg ccaggtagaa agctcctttg
     7021 tggaaacgct tcatctttcc gttgtaagtg cgtgtacctt cggggaagat agcgatggag
     7081 tagccctctt ttactttttt ccgcatccgt tccatatatt gttcgtagcc ttcgcctatg
     7141 taatagaaat cgacatagcg gatgattgct ccgaagaaag gagaatgcca tacccaatga
     7201 ttggttacca tcaggatttt agacgaaaga gacagcaata ccagaatatc gatgaacgac
     7261 tggtggttgg cgataataat tgccggatgc tgaaaacgtt cgttagcctt gttgatatgt
     7321 tcttttttaa cggcagtggc caatagtaga atccctttgc aggtgatttg tatcagtcgg
     7381 cataccaaac gttgtttgct gcttttccgc acaggcacca aataaaggac agcgatcagt
     7441 acacggagga agatacaacc gataaagaaa agcaggaaga gcaatacggt ccgtatcagc
     7501 ccgataagcg tataaggcgg caatcctttg gaagcgggtc ctgcaatgaa gaaccggaaa
     7561 atgagtggct gaatggtata ggcaaccaac actactgcta tcatgccgag aatggaaatc
     7621 aatgaaatgg attgcaaagc cggatgcttg gcaaaaacaa gtgctcccat gccgacaact
     7681 gtggtgaaag cagagaagaa gatggctgtt ttgtgagaat tcagtacctt ttggcctgta
     7741 cggtatttgt tttgtagccc gtccataatg aagatactga aatcgtctcc aattccaaag
     7801 ataaaggtgg acaggataat gttgatgatg ttgaactcaa tccccaaaat tcccatcaat
     7861 cccaggatga ttacccagct aactagcatc gggaggaaac tcatcaaggt aagttcgata
     7921 cgtccgtagg agaaccataa tgcgaagaat atcaggaaag aagagatata tagaatcagg
     7981 taaaagtcgt cattgatggc agatacccat ttattggcaa agtaggaacg gtcgaagatg
     8041 actacatcct ggtctttgct gaagtgctga tatacggttt ccttattctg gtcgctgatc
     8101 cgtatctggc tgataagcat ggtgatggaa tcggcagaag tttgccattc gttcagtagc
     8161 ttgccggata aatcgtcttc ttgagcggtg tagtgatatt caccgaaagg ttggttcagc
     8221 cattgataaa agggatcgaa gcttcccggg cggaaacggt attcagcggc agctgtttcc
     8281 agttgttcac ggatttgttg ttgcttttca tctgtccagt agtctttcca ttttttcagg
     8341 cgtagctgtt gctcttgtgg cgagatcaga aattgtgagg cggaagcata gtctttaatc
     8401 agtccctgat ctttcagtgc caataacttc tgattggtca ttgcataagt ttcggtggcc
     8461 tgattcatgt ctttgcctac gctgacaaaa agcactgtct tttcgtcgct gtcgaagagc
     8521 tgcattaatt tctcttccga ttgtttgagg tgttgaggtt catagttgag gctcatcatg
     8581 tcgttgttga agccgacctt ttgtgaggta aacaaacaga taactgtaat gaggagaata
     8641 ccgcctacca accatttatt cttttcgtaa gaatatgcgt ttattttctc gatgatgcgt
     8701 aatatacatc cctgtttgac gtctgcctgt cctttcagga aatgaggcag gtaaatgagg
     8761 cagaaaagag tagtacccac caatgccagg gaagcgaaca acccgaaatc gcgtaacaga
     8821 tcggaactgg tgaatatcaa tcccataaat gcgccgatgg tggtgaaact acctactgta
     8881 agcggatagg ctatctcttt aatcagttgt tgcacggtgg aaacatggtt ctgatgtgcc
     8941 aacatgtgga tggaatagct tagtgcaata cccatcactg ccgaaccggc tcccacggca
     9001 atggccgata tacttccttt gataaagaaa atcagaaaca gggcgaacaa tcctccgaag
     9061 agtaccggag taataatcaa tggtatcgat cgcttccgtt taaacacgag tgagataaac
     9121 actatgatga taagcagtgc cagtgaggaa gtcaaaatcg tatctttctt gatctgacgg
     9181 gcgttgtaga ctcctacgga gggaccgccg aaatattcga ctcgaatggt aggagattct
     9241 ccctgtacgt gttggagttc ttcttcgagt atttttatca gttcgtcatt ctttccggta
     9301 ctgcctgtgc tgaataccgg ggtaatgaac ataagcaagg tggaaccgtc tttggaaaag
     9361 atgtgttcgt catagatctc gtagttggct tccaactgga aatcctgcaa atgtttcagg
     9421 gcttcacttc ccagtccgag cgggtcccgg agaatataac ttcttaatgc gattccggca
     9481 ggagagagga gattggtata gttcttctgc atgatagctt gtataccttt ctctgtcaat
     9541 agggaatcga atcgttgata atccgtatct gtcaggaata acgggagatg ctcgtagaca
     9601 aagtctgtgg ctcctccgat gaggctttgg tctacttgtg cgaaaattcc cttaatcagg
     9661 gttcctccgg ctttttcagt cagggtttgt tgcagttgtc cggcagcttc tatcagggaa
     9721 tcaggttcta cctggtgaca ggtatctgcc gaggatagca taatgataat cttatccttg
     9781 attttgagat tgtcgaatac cttgattgtg ttttgggagt ctttggtgtc ggggaaaaat
     9841 tgtgtgatgt tctcttcgaa tcttacttgc agggcaaaga accccatcaa caggacacaa
     9901 ctgatgagtg acaaatagaa cagaatcttg tgcctctcaa aataatcata tagtccgata
     9961 aaaaactggg tcatatcttt tttttcctac acgccgtgag cagaatgaac gcgatggttc
    10021 ctgccagtat gctgcatacg actgcaaaga taacacttcc tattaaatat tgctctatga
    10081 ctgattttac attttcaaaa gaaagttcgt ttaagtgcag gtttacaggt tctcccagta
    10141 ctttacagcc ggttacataa cttccgtaca gtaaaaatgg tatcatcgga gggatgctaa
    10201 tgttggctgc tacaatagct atgactttgt ttaatcggaa caaatgtgcc aaaaacaacg
    10261 taatcagcat ttgatatccc catgccggaa cgatgcccat aaatacgccg agcatgatgg
    10321 ctgctgtaat ccgcaggtta gattcggggg agtgggtgat gtgattggag aaaaactgct
    10381 tgcaattctt ccaggtcagt ttacggaaaa agttccgtgg aacaatccaa aggaaagtga
    10441 cgagtaccag taccgtattc agaatactga tacgggtgaa atcacggaac gggcggaaat
    10501 gagaaacccg ttcttcctgt ggcggataat aaacgtgtac cggaatattt tttacgggat
    10561 tgcctcccca tgctgcaaaa acaagtgctt ccagttcgaa ctcatatttg gcagtgtaat
    10621 accacttgtc cacattcatt cgttggatag ggtagaggcg gtagccggat tgcgtatctt
    10681 gtagtttgat accggtttcg agggtgaacc aaaagttgga aaacttattg gcaaaggtat
    10741 tctttcccgg catattgtcc gaggtcagat tacgggagcc taccagtaac gtgtccggtt
    10801 ccttttctat ggcttcaatc aatacgggaa tgtccgaagc gaaatgctgt ccgtcggaat
    10861 caatggtgat ggcatatcgg aatccttgct tctttgcgaa agatagtcca tgttttaatg
    10921 ctactccttt tccttgattg acagggtggg tgatgatgtg aagattagct tcctgattca
    10981 gtatttcagg tgtttcatcc gttgaaccgt cattgacaac aaggatttcc ggtgcataaa
    11041 gacgtacact tgctatgact tctgccagtg tcttgccatt gttgtaactc gggatgatga
    11101 cgatgatccc taattgtttc aacttttcgt gccaataggc tgtacttatt tgctccttca
    11161 tgcttttggg gtaagtgcag cttttagttt aatgaaacat tcgtctttta tattttcttc
    11221 ctttataatg ctttcttttc ctgtgttctc ctttacaatt tcttcttttg caatatcctc
    11281 tttcacaatg cttttattta cggtatttcc ctttatagta ccttccgcct gtaactggaa
    11341 cttgccttct tctgtctctt tgagaatcag tacgattgct atccgaggcg tttctatagg
    11401 attgatagcc gaaagaaact tgcaggaaga cacttgtact atttgcaact tttgctgacg
    11461 aatattttct gcacattcct tgataagttg caatagacaa actccgggaa ctaccggatg
    11521 ttcaggaaaa tgtccctgat aaacagtgtg gtcaggattc aactctatct gaatagtcca
    11581 ggtagttgaa tccgatgact cggaggaaag gatagtatag aagttatcaa gtagcatata
    11641 ttaaatttct ttagatagtt tatccagacg gatcgttaac cgtatccacg gatgtttgat
    11701 ttttatttgt gccggttcac ccggagtgtc gccggtaatg tagaccactg attttccaaa
    11761 gccttttcca ctggttcttt tttgggtagc attgtctttg gtggctttca cacggacgtc
    11821 ttttccattt aagaacaaac gcctgaaatc catctctaac agtttcaata ccttttcttt
    11881 tttcatgggt tcaatgcagc tgttgacatt aaattgatcg tcatgcagag aaaaatcgaa
    11941 aaggcttaac ccgaagtagg tagacgccac gatccggatt tcgttatcag gcatacggcg
    12001 tactatcagc ataccactca tgtgatgttt catgaaatcc agttggatat tgtatttttg
    12061 tgattcttcc ccttgtgtca gttcgataac aggaggcaca gtactgcctt ccccgcttat
    12121 tcgtggagag caggacgttt gaacctgtat tcccaagaat aacagaaccg tcaggctaac
    12181 gaatcgcaaa cttcgtctca ttcttcagag agttgaactt tttattatag aattcgtatt
    12241 ctgtgtagtt tgtagctgtt tcggacagac ggagtttgtg caccgacata tctttcttgt
    12301 ccaaataaat ttcgataccg gcaatatagg cttgtactgc tttgttagtc ggcttaattt
    12361 taaccaaata atatcgtgcg tcttcaaaat attctagctg gtagttggat gacatcttag
    12421 acaggtcgcc tatcatacac gcagttagca tatcctgcat ctgtgccatc attttgttcg
    12481 aacttaggtt cataatactt ttcttgccat ccgatacgat tttgagctta ctcccgttta
    12541 tcacgatgag ataatccatt gggcggaagt attccataca gattttattg ctcttttggt
    12601 agtagaactt ccctttggaa gtaacctttt cgtcgaatac atcgagatat ttcacttggg
    12661 taaaatcgct ttcgatggac ttcacggttt gtgcctcctt tgccaggcgg ttttcaaact
    12721 cggtcttttg caccatcttt ttcatgctct gtgcatggac ggtggcgata gacaagaaga
    12781 aaagcgataa gtatagtaat aaagttctca tacattttta ttttatgcca atagtttgtc
    12841 cggacggaca acggtatatc cttgttcttt tagcaaatcc agtatttgtt tcactaactg
    12901 gtcgctgccg ggcatccggt cgtgcaacag aatgatggct cccggttcaa gacgtttccg
    12961 aatcctggca agtattttgt ccggagctga ctgttgcgta tctaatgtac ggatgctcca
    13021 tcctattgag gtgtatccta actgtcggac agctttcgca atcgtaggat tagtgacacc
    13081 gaatggcgga cgaaacaaag taaccggctg cgaagttact cgttctagtt cacactgaca
    13141 agtttgcagg tcttttttca ttttagagag tccatatagc ggaaataaac cggaatgact
    13201 atatgaatga tttccaatta gatgaccttc tgttaccata cttttcaaca gggcttcatt
    13261 tccttttatc ttgtgtccga tacagaaaaa acaggcagtt gcctgatatt cttttagtac
    13321 cttcaatact ttgggcgttt gaatgggatc gggaccgtcg tcaaaagtca gggcgacaac
    13381 tttttccgta gtacgttttt tgcaaaacga tcgtagataa attcccgact gaatgctata
    13441 ggaagcataa acgagaaagg acagtatcaa gaataaacat agaaggaggc aaacaatcat
    13501 catacgcttt tccgaattag aatcaatgag tgattgatgg agtggtggtg attataaatc
    13561 agtatattgg taggggtagt acagtttatt gatgtcttta ctgctttcca tacggcatac
    13621 gatgaggcgg taggatattc tccacattcg tccttaaaac taagatgaat actttccggg
    13681 aaaaggttgg tttcaagctc ttcatagata gaattgcttt cattcatcat aatctcctta
    13741 attattatat ctttttcatt tatgatactc tccccgttta taatacttct ctgattcgta
    13801 cttttccctt catttatagt actcttctta taaccagtga tttgctcgtg gtaatcacct
    13861 tgaagggatt gttttttgtt ctttccggta actaaccatt gaataccctg acactctaat
    13921 ccgtttcgtt gtaaaaaacg aataattcgg gaactgattt cttctgtcgt atgttgtccc
    13981 gtgaaagttt caagtcctcg tatttctgct aacggatgct ctccggcttc ccggcttaat
    14041 aggaagaatt gagcgccttc tccggcttct attcctttca gcagtcccaa gcgttgctga
    14101 atgatgtaac tggtttctgt catttcgtcc atggctccca ccagtatatt ctcgcttcct
    14161 tcttctattt tcatcatggc atccagcaaa gcgctttcaa aacttagtcc ccggtgaaca
    14221 taagtcatgt tataggcatg tatttgatga atcagtgcta tttgtgcacc aattgtattg
    14281 aatgtcgact gaataaaagg agtaggattc agcatccgct cttcattatc taacaggttg
    14341 ttcagaaact tttccgtatc aaccaggcag cccagccctg tggctgtgat aattccccct
    14401 atcttctcgg gagatagttc gcccatacat tccaatccgc aagccactcc cattttcaca
    14461 atacggctca tgcgcctgcg caaagttgca ttggcaataa tatccttata atcgggttca
    14521 caagcctgaa gaaaaggacg gtttgctgca acatcgagcg aatcatttac tttcggatta
    14581 ttttcttgtg aatgatttcc ttgtggatgg atagaagcga tgcgttgaat ataaactggc
    14641 tgcataggct caaaaactta aaggttcgtt cgtttgggaa aattcgttgc ggaaaagagg
    14701 agcgacgagt cgtttcctcc gaagccgaaa gaattggata atacatggcg gatcggcact
    14761 ccttcctgga aagatgtttc cggtatcaat cctgtttctg attttactcc tgtttctgac
    14821 aacagttctg tttccggcat aggctccgtg aaattcagat tcggataaat catgccttta
    14881 tctatggaaa gaacggaata aacagcttca attccttcgg aagctcctaa agtgtgtccg
    14941 ataaaagctt ttaccgaact aaacggtgga acatgttctc cgaagattct tcgtagtgcc
    15001 attccttccg atgcgtcatt accgggagta cctgtcccat gtacgttgat ataatcaata
    15061 tcttcaggag aaatgccact ggaagcgatg gcttcactca ttgatagaaa ggcgccatc
//
