LOCUS       c00003_gnlPro..        14217 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NAIEBDPA_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 02:03:40
            Original ID  :: gnl|Prokka|NAIEBDPA_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14217
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..408)
                     /locus_tag="ctg3_1"
                     /transl_table=11
                     /translation="MQTDGTLLVPDVPTVPYITGDGVGAEVTPAMQAVVDAAIRKAYGG
                     KRRIEWKEVLAGERAFNATGSWLPDETMETFQEYLVGIKGPLTTPVGGGIRSLNVALRQ
                     TLDLYVCLRPVRWYQGVQSPVKSPEKVNMCVF"
     protocluster    1..14217
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6970:13057]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6971..13057
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..14217
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14217
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(427..2670)
                     /locus_tag="ctg3_2"
                     /transl_table=11
                     /translation="MVYDVTMLEAFYAAYKGKVEHVRAILKRPLTLAEKILYAHLYDVA
                     DLKDYKRGEDYVNFRPDRVAMQDATAQMALLQFMNAGKDQVAVPSTVHCDHLIQAYKGA
                     KADIATARLTNEEVYDFLRDVSSRYGIGFWKPGAGIIHQVVLENYAFPGGMMVGTDSHT
                     PNAGGLGMVAIGVGGADAVDVMTGMEWELKMPKIIGVRLTGKLSGWTSPKDVILKLAGI
                     LTVKGGTNAIIEYFGPGTESLSATGKATICNMGAEVGATTSLFPFDGRMATYLRATGRD
                     CVVDWAESVGADLRADDIVTDEPSNYYDRVIEIDLSELEPYINGPFTPDAATPISEFAE
                     KVLLNGYPRKMEVGLIGSCTNSSYQDLSRAASLAKQVTEKNLSVASPLIVNPGSEQIRA
                     TAERDGMIEAFERLGATIMANACGPCIGQWKRQTDDPTRKNSIVTSFNRNFAKRADGNP
                     NTYAFVASPELTMALTIAGDLCFNPLKDRLVNHNGEKVKLSEPVGDELPLKGFEQGNEG
                     YIAPHGAKTEIRVKPDSQRLQLLTPFPAWDGQDLLNMPLLIKAQGKCTTDHISMAGPWL
                     RFRGHLENISDNMLMGAVNAFNGETNRVWNRSTNTYGTVSGTAKMYKSEGIPSIVVAEE
                     NYGEGSSREHAAMEPRFLNVRVILAKSFARIHETNLKKQGMLALTFVDKVDYDKIREHD
                     LLSVSGLVHFAPGRNLTIILHHEDGTKESFEVQHTYNEQQIAWFRAGSALNTR"
     CDS             2737..4674
                     /locus_tag="ctg3_3"
                     /transl_table=11
                     /translation="MKYFFYPERRFVTFAPIMSNNPKSPIIDLQQQQLLLRMEYEYEKE
                     EFKRQTETMGVARKVKRGLCWYPVSLGRSYYNSLNQLVIDITRTENKEIEHSFEFGRPV
                     CFFHQSFEGKVKYMDFIATVSFADEERMVVVLPGAGALAELQTDGILGVQLYFDETSYR
                     AMFEALEDTIRAKDNRLAELRDILLGTQKPGFRELYPVRFPWLNSTQETAVNKVLCTRD
                     VSIVHGPPGTGKTTTLVEAIYETLHREPQVLVCAQSNTAVDWICEKLVDRGVPVLRIGN
                     PTRVNDKMLSSTYERRFESHPAYPELWGIRKSIREMGSRMRRGSYSEREGMRNRMSRLR
                     ERATELEIQINADLFDSARVIASTLVSSNHRLLNGRRFPTLFIDEAAQALEAACWIAIR
                     KADRVILAGDHCQLPPTIKCIEASCGGLDHTLMEKVVQQKPSAVSLLKVQYRMHEAIMQ
                     FPSDWFYHGELEAAPEVRYRGILDFDTPMNWIDTSEMDFHEDFVGESFGRINKQEANLL
                     LQELETYIERIGKERILDERIDFGLISPYKAQVQYLRGKTKGSSFLRPFRSLITVNTVD
                     GFQGQERDVIFISLVRANEDGQIGFLNDLRRMNVAITRARMKLVILGDASTLTKHPFYK
                     RLMLFIKKED"
     CDS             complement(4818..6776)
                     /locus_tag="ctg3_4"
                     /transl_table=11
                     /translation="MYFNLPKRMINITKLVCVIGVVSVAFSSCLQKDVYDPANSGDKEE
                     EVTLDNYFNFATTKNIQLNIDYGKECPQTYFEVYAENPLSYVAEGGQIIKKAGVSHIAT
                     GFTDIQGRYIKPASFPTTVSEVYIYSPDFGVPTLYKTKIVGSDVSAEITFENALDVTAV
                     DSSTRSAQTRSSLKFITNVIPNVLGTWNVNTGRPNYLDASKKINVDATLKSYITAYFPE
                     GKNNKGTLVSDDADILITKDANVVINYFGGNTAAQSVFAYYCYPKDASVDKIKEATKHA
                     CVIFPNAHGNSLGNYSGVAVNLKYINEAGNFPQENPERIPANTKIGFLIWNNGWKNTKA
                     NGNMFYSTKSLNSDKISHTAIFAAKNKAGERVNVITMEDWKNDNDYNDVAFVISSNPIT
                     AIEVPEVPNPGDRQGTENYSGVLGFEDNWPEQGDYDLNDVVMKYQSSVDYNIDNKVLNI
                     IDKFTLAWTGANYKNSFAYEVPFDLSKASQVIINGDEITSYSGNVITLFKDAKAELGVS
                     NVNAEDMINQNIQEKTYTVSIQFNNPTLDKSVVVAPYNPFIKVFNSATEVHLTDHKPTT
                     GANNRFPSGADISRGDVDGTYFICKDGFPFAIHVDARLDASILNLDLKKENQRIDKTYP
                     KFAEWAKTRDPQIKWWK"
     CDS             complement(6971..8014)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_5"
                     /sec_met_domain="IlvN (E-value: 6.9e-47, bitscore: 148.5,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 6.6e-42, bitscore: 132.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTTETVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQREGKTYDKAVADGWVPGETLFGIEEACEKGTIVMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGKAYERTIALGIGIGSGYLFETTFQREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHSPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYNSVKTGNEAQISIDSNSQPDYREKLNEELRQLRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(8082..8825)
                     /locus_tag="ctg3_6"
                     /transl_table=11
                     /translation="MSEENRIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHANDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYENFSVQTWVENVYRLFTDRNFAIIDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVDYVCDEPCPIEKPSRIKVTSDQPIATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYKTKRIRRFEMAYVAESYFGDELSFFCDEV
                     NANEFHVEVKKNGNEVVCRSKVIFE"
     CDS             complement(8831..9388)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_7"
                     /sec_met_domain="ALS_ss_C (E-value: 2e-19, bitscore: 59.1,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDIIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQENP
                     EASKLIRRYNARIVEVNPVFSIVEKNGMSEDITSLYGELKALNCVLQFVRSGRVAITTS
                     CFERVNEFLDGREAMYNQSKNQ"
     CDS             complement(9439..11133)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_8"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-47, bitscore:
                     150.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLITGAEALMRSLEHQGVTTIFGYPGGSIMPVFDALYDHQNIL
                     NHILVRHEQGAAHAAQGYARVSGDVGVCLVTSGPGATNTVTGIADAMIDSTPIVVIAGQ
                     VGTGFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAVARAFYIARSGRPGPVVLDF
                     AKNAQVEKTKYEPTKVDFIRSYVPVPDADEESVQAAAELINNAERPLVLVGQGVELGNA
                     QSELREFIEKADMPAGCTLLGLSALPTEHPLNKGMLGMHGNLGPNINTNKCDVLIAVGM
                     RFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDVAVLGDCKETLASVTKLLKKNAH
                     AEWIDSFKEYEKVEEEKVIRPELHPATNSLSMGEVVRAVSDATHHEAVLVTDVGQNQMI
                     SARYFKYTKERSIITSGGLGTMGFGLPAAIGATFGAPERTVCVFMGDGGLQMNIQELGT
                     IMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKVASAYDIPSKRAFT
                     REELKEAIAEMLATDGPFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             complement(11258..13057)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_9"
                     /sec_met_domain="ILVD_EDD (E-value: 8.2e-217, bitscore:
                     710.2, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQLRSSFSTQGRRMAGARALWAANGMKKNQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQLVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPAVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVSDQEVANIEQNACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRTQLFKDAAELIVKNAKLYYEEGDESVLPRSIATRQAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAEVDFKMDDIDMLSRKAPCLCKVAPNTQKYHIQDVNRAGGIIAIMDELAKGG
                     LIDTSVRRVDGMSLAEAINEYSITSPNVSEKAIKKYSSAAGNKFNLVLGSQGMYYKELD
                     KDRANGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQEA
                     ACEGILGGRVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGNIGKIVDGDIIEIDIPARKINVRLTEEELAARPMTPVTRDRY
                     VPKSLKAYASMVSSADKGAVRII"
     CDS             13539..14117
                     /locus_tag="ctg3_10"
                     /transl_table=11
                     /translation="METVENKYITVAYKLYTMEDGEKELFEEAKAEHPFQFISGLGTTL
                     EDFENQITALSKGDKFDFTIPADKAYGQYDEQHVIDLPKNIFEIDGKFDSERIKEGNIV
                     PLMTGDGQRVNASVVEIKPDVVVVDLNHPLAGADLIFEGEILESRPATNEEIQELVKMM
                     SGEGGCGCGCDSCGDGCGDDCGCEGGHCH"
ORIGIN
        1 gaacacacac atgttcactt tctccggtga tttgacaggc gactgtactc cctgatacca
       61 acgaaccgga cgaagacaga cgtataaatc aagtgtctga cgcagtgcta cgttcaacga
      121 acggattcca cctccgacag gagttgtcaa cggacctttg attcctacca ggtattcctg
      181 aaaggtttcc attgtttcat ccggcaacca ggaaccagtc gcgttgaagg cacgttctcc
      241 cgccaacact tctttccatt cgatccgacg tttgccgccg tatgctttcc ggatagctgc
      301 gtccactacg gcttgcatgg caggagtcac ttcggctcct actccatcgc cggtaatata
      361 aggtacggta ggcacatcgg gtaccaacag cgtaccatct gtttgcatgg ttattttgct
      421 cattttttat cttgtattta aggcagaacc ggcacggaac caagctatct gctgttcatt
      481 ataggtatgt tgcacttcaa aactttcttt cgttccgtct tcgtgatgaa gaataatcgt
      541 cagattgcgc cccggtgcga aatggactaa gcctgatacg gacaaaagat cgtgttcccg
      601 aatcttgtca tagtctactt tatctacaaa agtaagagca agcattcctt gttttttcag
      661 atttgtttcg tggatacggg caaaactctt agccaaaatg acacgtacat tgaggaagcg
      721 tggttccatg gctgcatgtt cacggctgga accttctcca taattctctt cggcaacaac
      781 aatagacgga ataccttcgg atttatacat ctttgccgta ccggaaactg ttccataagt
      841 atttgtcgaa cgattccaaa cacggttcgt ttcaccattg aaagcattga cagctcccat
      901 cagcatattg tcggaaatat tctccaaatg tccccggaaa cggagccacg gacctgccat
      961 agagatatgg tcggtagtac attttccctg tgctttaatc aataaaggca tgttcagcaa
     1021 gtcttgtccg tcccatgccg ggaaaggagt cagaagctgg agacgttggg aatccggttt
     1081 taccctgatt tccgtttttg ctccgtgcgg ggcaatatac ccttcatttc cctgttcaaa
     1141 acctttcaag gggagttcat ctcctacagg ctcggagagt ttcacttttt ctccgttatg
     1201 attcaccagt ctgtctttca acgggttgaa acagagatca ccggctattg ttaacgccat
     1261 cgttagttcc ggagaagcta caaacgcgta tgtgttggga ttaccgtcag cgcgtttggc
     1321 aaaattacga ttgaaagagg tgacgattga gttttttcgt gtcggatcgt ccgtctgacg
     1381 tttccactga ccgatacaag gtccacaagc atttgccata atcgtggctc ccagccgttc
     1441 aaaagcctca atcataccgt ctctttcggc agtagcccgg atttgctccg aacccggatt
     1501 gacgatcagc ggagaagcaa cgctcaaatt cttttctgtc acctgctttg ccaaagaagc
     1561 tgcacggctc aaatcctgat aagaagaatt ggtacatgaa cctatcaagc ctacctccat
     1621 tttacggggg tagccgttca ataacacttt ttctgcaaat tcagagatgg gagtagcggc
     1681 atccggtgta aacggcccgt ttatataagg ttcgagttct gacaagtcaa tttcaatcac
     1741 acggtcgtaa tagttggatg gttcgtcggt cacaatgtcg tctgcacgaa ggtctgcacc
     1801 aacagattca gcccaatcga ctacacaatc tcttccggta gctctcaaat aagtagccat
     1861 gcgtccgtca aacgggaata aagaggtagt agctccaact tcggcaccca tattgcaaat
     1921 ggtagctttc ccggtagcag aaagggattc ggttccggga ccaaaatatt cgataatagc
     1981 attcgttcct ccttttacgg taaggatgcc ggccaatttc aggattacat ctttcggaga
     2041 ggtccaaccg cttagttttc cggtcagacg gacaccgata atcttcggca ttttcagctc
     2101 ccattccatt cctgtcatca catccacggc atccgctcca ccgacaccga tagccaccat
     2161 gcccagtccg cctgcattag gcgtatgaga gtctgttccc accatcatac cgccggggaa
     2221 agcatagttt tcgagcacta cctgatggat aattcctgct cccggtttcc agaagccgat
     2281 gccataacgg gaagatacat cacggaggaa atcgtatact tcttcattgg tcagtcttgc
     2341 cgtagcaata tccgcctttg cacctttata cgcctgtatc aagtgatcgc aatgcactgt
     2401 cgaaggcaca gccacctgat ccttacctgc attcataaat tgaagcaaag ccatctgcgc
     2461 agttgcatcc tgcatagcca cacgatcggg acggaaattc acataatcct ccccccgttt
     2521 gtaatctttc aaatcggcta catcatacag atgagcatac aaaatcttct cggccaacgt
     2581 caaagggcgt tttagtatag cccgtacgtg ttctaccttt cctttataag cagcgtagaa
     2641 agcttctaac atagtcacat catataccat attgcttttt gtttttttag tctatctatt
     2701 aaaataacga acgacgttcg agtaatgttt aacaaaatga aatatttttt ctacccggaa
     2761 cgaagatttg ttacctttgc gcctattatg agtaataatc cgaaaagtcc cattatagac
     2821 cttcagcaac agcaactcct cctgcggatg gagtatgaat atgagaagga agaatttaag
     2881 cggcagaccg aaacaatggg cgttgcccgt aaagtgaagc gcggtctctg ctggtatcct
     2941 gtctctcttg gccgaagtta ctacaattcg ctgaatcagc ttgtaataga tattacacgg
     3001 accgaaaata aagaaataga gcattccttt gagtttggcc gtcctgtttg ctttttccac
     3061 cagtcattcg aaggaaaagt gaaatatatg gatttcatcg ctaccgtcag ctttgccgac
     3121 gaagaacgaa tggtcgtagt actccccgga gcgggagctt tagcggaact gcaaactgac
     3181 ggtatactgg gggtacaact ttattttgac gaaacatcgt accgggccat gttcgaggca
     3241 ctggaagaca cgatacgtgc caaggacaac cgcctggcgg aactgcgcga cattttgctg
     3301 ggtacccaaa agccgggatt ccgcgaatta tatcccgtcc gctttccatg gttgaacagt
     3361 acacaggaaa cagctgttaa caaggtgctc tgtacgcgtg acgtatctat tgttcacggt
     3421 cctccgggaa ccggaaagac aacgactctt gtcgaagcga tttacgaaac attgcatcgg
     3481 gaaccacaag tgcttgtttg tgcgcaaagc aacacggctg tcgactggat ttgtgagaaa
     3541 ctggtagatc ggggagtccc cgtgctccgc attggaaatc caacccgggt caacgacaaa
     3601 atgctttcat ccacctacga acgccggttt gaaagtcatc ctgcctatcc ggagctttgg
     3661 ggaatccgta aatctatccg cgaaatgggt agccggatgc gccggggtag ttattctgaa
     3721 cgggaaggaa tgcgtaatcg catgagtcgt ctccgcgagc gtgccacgga attggaaata
     3781 caaatcaatg ccgatctttt cgacagtgcc cgcgtaattg cttctaccct agtcagcagc
     3841 aaccaccgcc tgctcaacgg acgtcgtttt ccgactttat tcatcgacga agctgcacaa
     3901 gccctcgaag ctgcctgctg gatcgctatc cgcaaagcag accgggtcat ccttgcagga
     3961 gatcattgtc aacttccgcc gactatcaaa tgtatagaag cctcctgtgg aggattggat
     4021 catacattaa tggaaaaagt agttcagcaa aaaccttccg cggtctctct attaaaagta
     4081 cagtacagaa tgcatgaagc catcatgcag tttccctctg actggtttta tcatggagaa
     4141 ctggaagctg ctccggaagt acgctatcgg gggattcttg atttcgacac tcccatgaac
     4201 tggatcgata cttcagagat ggactttcac gaagattttg taggcgaaag cttcggacgc
     4261 atcaataagc aggaagccaa cctactacta caagaactgg aaacttacat tgaacgtatc
     4321 ggcaaagagc gaatactgga tgaaagaatt gatttcggtc tgatttcacc ctacaaggcg
     4381 caagtgcaat atttgagggg aaagaccaaa gggagcagct ttttacgtcc tttccgcagc
     4441 ctcatcaccg taaacacggt agacggtttt cagggacagg agcgagatgt cattttcatc
     4501 agtcttgtac gtgccaacga ggatggacag attggattcc tgaatgattt gcgaagaatg
     4561 aatgtagcga ttacaagggc acgaatgaag cttgttatat taggagatgc ctccaccctt
     4621 accaaacatc ctttctataa aagattgatg ttattcatta aaaaggagga ttaaatactt
     4681 aatcctcctt ttaacaaagc acactttctc ccgaaaccac acttttttta acacaaacaa
     4741 aacaaacaat attttacatc agtactattc ttaatttttc accctcaaag atagtcgatt
     4801 attccaatgc actccaacta tttccaccat tttatttgcg gatcgcgcgt ttttgcccat
     4861 tctgcaaatt taggatatgt tttatcaatg cgctgattct cctttttaag atctaaattc
     4921 aaaatagaag cgtccaaacg agcatctaca tgaattgcaa acggaaaacc atctttgcaa
     4981 atgaaatagg taccatctac atcaccacga gaaatatcag ctccggaagg gaaacgatta
     5041 ttcgcaccag tcgtcggctt atgatctgtc agatggactt ctgtggcaga gttgaatact
     5101 tttataaaag ggttataagg agctaccact actgatttat caagagtagg gttattaaat
     5161 tgtatggata ccgtatatgt cttctcttga atattctgat taatcatatc ctccgcattc
     5221 acattagata ctcccagttc ggctttagca tccttgaata atgttatcac attacctgaa
     5281 taggaagtaa tttcatcgcc attgattatt acttgggacg ctttactcaa atcgaaagga
     5341 acctcatacg caaacgagtt tttataatta gctcccgtcc aagccaatgt gaacttatca
     5401 ataatattaa gaactttatt atctatatta taatcaacac ttgactgata tttcatgact
     5461 acatcattca agtcataatc tccttgttca ggccagttat cttcaaagcc aagcactcct
     5521 gaatagtttt ctgtcccttg tcgatcaccc ggattaggaa cttccggcac ctcaatagca
     5581 gtaataggat tggaagatat tacaaaagca acgtcattat agtcgttatc atttttccag
     5641 tcttccattg taatcacatt cactctttca cctgctttat tttttgctgc aaagattgca
     5701 gtgtgtgaga ttttatcact atttaaagat ttggttgaat agaacatatt tccattagcc
     5761 ttggtgtttt tccaaccatt attccaaatc aagaaaccta tttttgtatt tgccggaata
     5821 cgttcggggt tctcctgcgg gaaattacca gcctcattta tatattttaa attaaccgca
     5881 accccactat aatttcccaa actatttcca tgtgcattag gaaatatgac acaggcatgc
     5941 tttgtagcct cctttatttt atcaacagaa gcatctttag gataacaata ataagcaaat
     6001 acactttgtg cagcagtatt tcctccaaaa tagttaataa caacattggc atcttttgtt
     6061 atcagaatat ctgcatcatc ggacaccaat gttcctttat tattctttcc ttccgggaaa
     6121 tatgctgtta tataactctt aagcgttgca tccacattaa tttttttaga agcatccaga
     6181 tagttaggtc taccagtatt tacattccaa gttcctaata cattcggaat tacatttgta
     6241 ataaatttca aagaagaccg tgtttgtgca cttctcgttg atgaatctac agcagtaacg
     6301 tcaagagcat tctcaaaagt gatctccgca ctgacatccg aaccgactat tttagtttta
     6361 tacaaagtcg gcacaccaaa atccggagaa taaatataaa cttctgaaac tgttgtcggg
     6421 aaagaagcag gcttgatata acgtccttgt atatcagtaa atccggttgc aatgtgtgaa
     6481 acccctgctt tctttataat ctgaccgcct tctgccacat aagaaagcgg attttcagca
     6541 taaacttcaa aatatgtttg gggacattcc tttccataat caatattcaa ttgaatattc
     6601 ttagtagtag caaagttgaa atagttatct aaagtaacct cttcttcttt atctcctgaa
     6661 ttagcaggat catatacatc tttctgcaaa cagctggaga aagcaacaga aacaacacca
     6721 ataacacata ctaatttagt aatgttaatc attcttttgg gcaagttaaa atacatcata
     6781 cttctcgttt attttatttg atggtgcaaa tataaacata aacttgtata ttttagtcat
     6841 attatagata tatttttcta aaaaaagcaa tttaaaggat tcactcctcc ttttatacaa
     6901 tgtatttcca ataaaaaagg agagaactat ttgctctctc ccctcttaaa acttgtataa
     6961 tttatccagt ttaattattc tccggacgaa gtttacgaac agttacagca gtctgccaca
     7021 tttcgctttc gcgtaattga cggagttctt cgttcaattt ttcacgataa tcaggttgtg
     7081 aattactgtc aatagaaatc tgtgcttcgt taccagtctt cacactgtta tacaactttt
     7141 caactaccgg tttaatagca tcgtggaatg ggcccatcca atcgagagca ccacgttgag
     7201 cagtagtaga gcagttagcg tacatccagt ccataccgtt ctttgcgaac aacggcatca
     7261 acgactgtgt cagttcttcc actgtttcat tgaatgcttc agaaggacta tgaccgtttt
     7321 cacgcaatac ttcgtactgt gccagcaaca aaccttggat agcacccatc aatgaaccac
     7381 gttcacctgt caagtcagaa gtagcttcac gttggaaagt tgtttcgaac agataaccgg
     7441 aaccgatacc aatacccagt gcgatggttc tttcgtaagc cttgcctgta gcatcctgat
     7501 agatagcata agaagagttc aagccacgtc cttcgaggaa catagtacgc aaagatgtac
     7561 ccgaaccttt aggagcaacc atgataacgt cgatatcagc aggaggaact acacctgtac
     7621 ggtcgttcca agtgatagca aaaccgtgtg agaaataaag agcttttccg gcagtcaggt
     7681 aaggcttgat agtaggccat actgacatta ctgctgcgtc agacaacaga cacattacaa
     7741 tagtaccttt ctcacaagct tcttcgatac cgaacaaagt ttcacccgga acccatccgt
     7801 ctgctactgc cttatcgtat gtttttcctt cacgttgacc aacgattaca ttgaaaccgt
     7861 tatcacgcaa gttcagtgcc tgtccaggac cctgtacgcc ataaccgatt acagcgattg
     7921 tttcattttt caatacttca cgagcttttt ccaatggaaa ttcgtcacgg attactacag
     7981 tttcagtagt acctccaaaa ttcaactgtg ccattttctt tttgttttta gtttttgatg
     8041 acttatgcca tctgttatta attgatttta tattctcaca tttattcaaa tatcactttc
     8101 gagcggcaaa caacttcgtt gccattcttc ttcacttcta cgtgaaactc gtttgcgttc
     8161 acttcatcgc agaagaaaga gagttcatca ccaaaatagc tttccgccac atacgccatt
     8221 tcaaaacgac ggatacgttt ggtcttatac aattcaatcg ggaacaaatc aaggatatgc
     8281 tcgatgtaac ggatgctgtt tacatgaccg ttgatatcta tatcactgta ttttgccgtc
     8341 agggtagcta tcggctgatc gcttgtcact ttgatgcgtg aaggcttttc aatcgggcaa
     8401 ggctcatcac agacatagtc tacgatactt cccccatgca aagtcaacaa gtcggcaggc
     8461 ttgcgggtat taagattaat cattgcccat acggaacgtg cgtagccaat cttcttccca
     8521 tccttatcaa taatagcaaa attacggtcc gtaaacaaac ggtagacatt ttccacccac
     8581 gtctgaaccg agaaattctc atactgataa ggcatttcat ccaactcaat agccagacgt
     8641 gaaagcaccc atgtgtaatt atcctcattc agcgttgcaa taccaaaacc acggtcattg
     8701 gcgtgaaaac ctgcacaatt cagcagatga tttcccagta cccccatggt cagacgtccg
     8761 ttgaagtcaa catggaacgg ttctgccaca aactgataag tccctattct attttcttca
     8821 ctcattattc ttattggttt ttactttggt tatacatagc ttcccgtcca tcgagaaact
     8881 cattcacccg ttcaaagcag ctggtagtaa tcgctacacg tcccgaacga acaaactgca
     8941 aaacacaatt caaagccttc agttcaccat agagcgaagt tatatcttcg ctcattccat
     9001 ttttctcgac aatagaaaat accggattga cttccactat acgtgcattg tatctacgaa
     9061 tcagcttgga tgcttccgga ttctcctgaa aagcaggagt agacacctta tataatgcaa
     9121 tctcgtggaa ataaatctca tcctctgtga aataatgtgc ctgaatcacg tcgatcttct
     9181 tttcgatctg tttcactacc ttctcaatga tgtccttatc agtccaggct gttattgtat
     9241 acttatgtac acctttaata gaagaagcag atacattcag actctcaata tttatttgcc
     9301 gacgggtaaa tacagcagtt acctgattca gcaatccagc tatattctcc gaatgaacaa
     9361 tgattgtata taacgtttta tcactcataa ctctaatttt ttaaatgcga actctccatt
     9421 ctcaactctc aacttctcct agcactccag caacatctgg tttaccgaac cacccggagg
     9481 agtcatcggc aaaacattgc cttcttccac cacgcaggct tcgagcagga acggaccatc
     9541 cgttgccagc atttcagcaa tagcttcctt cagttcttca cgagtgaaag cacgtttgga
     9601 aggaatatca taagccgagg ccactttcat ataatccgga ttcaacatcg gggtaaacga
     9661 atagcgacgg ttgaaaaaca tagcttgcca ctgacgtacg tttcctaggt aattattgtt
     9721 cagacagata atcttcaccg gagctttctg ctccataatc gtacccaatt cctgaatatt
     9781 catttgcagt ccgccatctc ccataaatac gcatacggta cgttccggtg ctccgaaagt
     9841 tgccccgata gctgcgggaa gcccgaagcc cattgttcca agtcctccgg aagtaatgat
     9901 actgcgttct ttcgtatatt taaagtagcg tgcagatatc atctgatttt gacctacatc
     9961 tgttaccaaa acagcttcat ggtgagtagc gtcactaacc gcacgtacca cttcccccat
    10021 actcaaagag tttgtggcag gatgaagttc tggacggatt actttttcct cctctacttt
    10081 ctcatattct ttgaagctat caatccattc ggcatgagcg ttctttttca ggagtttcgt
    10141 cacagaagcc agtgtttcct tgcagtctcc caatacagct acatctacct ttacattctt
    10201 attaacttcc gcaggatcga tatcaaaatg aatcactttt gcctgtttgg cgtaagtagc
    10261 caaattaccg gtcacacggt cgtcaaaacg cataccaaca gcaatcagca catcacattt
    10321 attggtattg atattcggtc ccagattgcc gtgcataccc aacatacctt tattcaacgg
    10381 atgttctgtt ggcaaagccg aaagtccgag cagcgtacaa cccgcaggca tatccgcttt
    10441 ttcgataaac tcgcgcaatt cgctctgtgc atttcccagt tcaacacctt gtccaaccaa
    10501 tacaagcgga cgttcagcgt tattaatcag ttcggcagca gcctgtacag actcctcatc
    10561 cgcatcggga acaggaacat aactacggat aaaatcgact ttcgtcggtt cgtatttcgt
    10621 tttctctact tgcgcatttt tggcaaagtc cagtaccacc ggccccggac gaccactacg
    10681 agcaatgtaa aacgcacgtg ctaccgccca ggctacatct tccgcacggc gaatctgata
    10741 actccattta gtgattggct gggtgatacc taccaagtca acttcctgaa aagcatccgt
    10801 cccaagaaag cctgttccta cctgtccggc aatcaccacg ataggcgtac tatcgatcat
    10861 cgcatccgca atgcctgtta ccgtattggt tgctccggga ccgctcgtca ccaggcaaac
    10921 acctacatca cccgatacac gggcataacc ctgtgcggca tgggcggctc cctgttcgtg
    10981 acgaaccaag atatggttca atatattttg atgatcgtac aaggcatcga ataccggcat
    11041 aatagaacca ccggggtaac caaagatggt agtcactccc tgatgttcca aggagcgcat
    11101 caaagcctct gcacctgtta ttaaatcttt catattagtt gatagttgat aaatgataaa
    11161 tgatagttga gaaatgacag ttgaaaatga atggtttaca atcattgcgc taagtgctgc
    11221 gcagctaact attacctatc aactatcacc aactatatta tataattctc actgctccct
    11281 tatcggcaga gcttaccatg ctggcatacg ccttcaggct cttcggtaca taacggtcac
    11341 gagtgacagg agtcatcgga cgagccgcca gttcttcctc cgtcagtcgc acgttaatct
    11401 tccgggccgg aatatcgatt tcgataatgt ctccgtctac aatttttccg atattgcctc
    11461 cagctgccgc ttcaggagaa atatgtccga tactcaatcc ggaagttcca ccgctgaaac
    11521 gtccgtcggt aatcaaggca cattcttttc cgagatgacg ggattttata taagaggtag
    11581 gataaagcat ttcctgcata ccgggaccac ccttcggacc ttcgtgcgtg atgacgacga
    11641 cgtctccact gacgactcga cctccgagga taccttcaca ggctgcttct tgtgaatcaa
    11701 atactttggc aggtccggta aacttccaga tactttcgtc tacacctgct gtttttacta
    11761 cacaaccatc ttgagcaata ttgcctttca atacggccag tccgccgtct ttgctgtaag
    11821 catgttccaa gtcacggata catccgtttg cacggtcctt atccagttcc ttatagtaca
    11881 taccttgtga accaagtacg agattgaatt tatttccggc tgcgctcgaa tatttcttaa
    11941 ttgctttttc gctcacattc gggctggtga ttgaatattc gttaatggct tctgccagtg
    12001 acattccgtc tacccggcga acggatgtat ctatcaaacc tccctttgcc agttcgtcca
    12061 taatggcaat gataccaccg gcacggttta catcttgaat atgatatttc tgtgtattgg
    12121 gagccacctt gcagagacaa ggagccttgc gggaaagcat gtcgatatca tccatcttga
    12181 agtctacctc tgcttcgtga gcaacagcca acaagtgaag aaccgtattg gtagatcccc
    12241 ccattgctat atccagcgtc atggcgttca ggaaagcctg acgggtagcg atgctacggg
    12301 gaagtacact ttcgtctcct tcttcataat ataattttgc atttttcacg atcagttccg
    12361 cagcgtcttt gaaaagttgc gtacggtttt cgtgtgtcgc tacaatggtt ccgttgccgg
    12421 gaagagccag tccgattgct tcattcaggc agttcatcga gttggcggta aacataccgg
    12481 agcagcatcc gcaagtagga caagcatttt gctcgatatt cgctacttcc tgatcgctaa
    12541 cactttcgtc ggccgattta atcatcgcat cgatcaaatc caggtgctgg ccattccatt
    12601 ctcccgcttc catcggacca cccgatacaa atacggcagg gatattcaga cgcatagccg
    12661 ccatcaacat tccgggagtg atcttatcgc aattgctgat acataccatt gcatctgcct
    12721 tgtgcgcatt gaccatatat tctacgctgt ctgcaataat gtcacgtgaa ggaagcgaat
    12781 aaagcatacc gtcatgtccc attgctatac catcgtcgat agctattgta ttgaattccg
    12841 cagcgaagca tcccagcttc tcaatctctg ccttcaccag ctgaccgatt tcatgtaggt
    12901 gtacatgccc cgggacaaac tgtgtgaacg aattgacgat agcgataatg ggtttaccca
    12961 tctgattctt cttcatgccg ttggctgccc acaatgcacg ggctcccgcc atccgacggc
    13021 cttgtgtact aaacgaactg cgtaattgct ttttcatttc aatctatctt ttaattaaag
    13081 agccttcctc acacaagtga gaaaggctct aaattctatc ttttatggta cgaacacata
    13141 caacacaaaa acctttctca cgctcttgat gggaccacca cgacgcgaat aatatgcagg
    13201 actgctaggt taatagatgt atgtaacata ttcatatctt cttttcttta ttttcgtgct
    13261 gcaaaggtaa gggctttttt attatatcca aacaaatcga agaaaaaaat cacttaaaag
    13321 cgaataattg taagaaaaga gaggtattat ttctctattt tatcacttaa aggttgaatt
    13381 tacaactatt atctaactgc gcacctcact ttctttttct gacaaaagca cttaataatc
    13441 tgaaatttac cctccctata ccggagtaca agcaaataat tcgtatcttt gtagacccgt
    13501 atttacggga attattaatc agaaacaaaa aagatcagat ggaaacagta gaaaacaagt
    13561 acattaccgt tgcatacaaa ctatatacaa tggaagatgg tgaaaaagag ttgttcgaag
    13621 aagcaaaagc agaacatccc tttcaattca tttcaggatt aggaacaaca ctcgaagatt
    13681 tcgaaaatca gataactgct ctttctaaag gtgataaatt tgattttacc attccggcag
    13741 ataaggctta cggacaatat gacgaacaac acgttattga cctccccaaa aatatttttg
    13801 aaatagatgg caagtttgac agcgaacgta ttaaagaagg taacatcgta cctttgatga
    13861 ctggtgacgg tcagcgcgta aatgccagcg tagtagaaat caaaccggat gttgtagtag
    13921 ttgacctcaa tcacccgttg gctggtgccg acctgatttt cgaaggtgaa atactggaaa
    13981 gccgtcctgc taccaacgaa gaaatccagg aattggtgaa aatgatgagt ggcgaaggtg
    14041 gttgcggttg cggatgcgac agctgcggtg atggctgtgg cgacgactgc ggttgcgaag
    14101 gcggacactg tcattaattg aagtataaag tattaagtat taatttcgtg cggatatagc
    14161 cggagtttta atacttaata ctttttttat gccgtcattc cggctaatac ctaatac
//
