LOCUS       gnlProkkaKJMHMHAP_34   15216 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KJMHMHAP_34.
ACCESSION   gnlProkkaKJMHMHAP_34
VERSION     gnlProkkaKJMHMHAP_34
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 23:41:01
            Original ID  :: gnl|Prokka|KJMHMHAP_34
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15216
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15216
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4865:5216]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4866..5216
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15216
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15216
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2..184
                     /locus_tag="ctg34_1"
                     /transl_table=11
                     /translation="MIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARANPLRKQYYEK
                     RDDSDKLKLDTVDED"
     CDS             194..1435
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg34_2"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             1422..1949
                     /locus_tag="ctg34_3"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             1955..2728
                     /locus_tag="ctg34_4"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQPAEEMPKLKGYELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             2735..3130
                     /locus_tag="ctg34_5"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPAAETPAPAAE"
     CDS             3380..4768
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 93; E-value: 2.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg34_6"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFALFGVLALVVALMLKAENKKKEYGLEEA
                     NIQK"
     CDS             4866..5216
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_7"
                     /sec_met_domain="PqqD_RRE (E-value: 1.8e-10, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6.6e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(5235..5519)
                     /locus_tag="ctg34_8"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(5556..6623)
                     /locus_tag="ctg34_9"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKTAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKMPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             complement(6697..8208)
                     /locus_tag="ctg34_10"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHTLTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             complement(8483..8599)
                     /locus_tag="ctg34_11"
                     /transl_table=11
                     /translation="MRNTLKYYENKAAFEPKYGRTYEKYRFEKVFLIRYLFD"
     CDS             9270..9494
                     /locus_tag="ctg34_12"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             9688..11232
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 48.8; E-value: 6.5e-15)"
                     /gene_kind="transport"
                     /locus_tag="ctg34_13"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASTLDNTN
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPRDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKADHISHPKMDKRTKVRNTLVITILTIALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDIFGWEMPASW
                     FQSFNPLFVVVLAYIMPGVWGFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAVP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             11273..11809
                     /locus_tag="ctg34_14"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             11869..12438
                     /locus_tag="ctg34_15"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             12528..13682
                     /locus_tag="ctg34_16"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAET
                     GEYLCDVTEDGQEVVLLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     VTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEDIVYEYEEDGDDDIDYEYEEDWEEE"
     CDS             13679..14491
                     /locus_tag="ctg34_17"
                     /transl_table=11
                     /translation="MISLTKHNELKGYKSLDAYPEVAHFVTTRHGGISTGAYGSFNCSP
                     YTNDSCVNVNRNQNWLFQCMNHQIKELFIPEQSHGCASLIINESFFKESLERRRLLLRG
                     MDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSHVMDNMTQKF
                     GTQGEDVIACIGPSISLESFEVGDEVYDAFEESGFDMSLISMKKKETGKYHIDLWEANR
                     IELLNRRVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRTLSGIMIRK"
     CDS             14542..15207
                     /locus_tag="ctg34_18"
                     /transl_table=11
                     /translation="MFEIKVSKEIKDACPVFAGAAVYAVVKNTAYSEGLWQEIDAFTKQ
                     LTSTTQMEDIKHQPVIFATREAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDL
                     INLVSLRTGHSIGGFDADKIQGTHLELGIGKAGEPFEGIGRGVLNIEGLPVYRDSFGGI
                     GTPTSDHERTKMDLETTHILAIVNGYNGKEGLQEAVEMIQTLLRNYTESDGGEIVFFE"
ORIGIN
        1 cgatattgca ggtaagggag tggcttgtga agattctttc cgtcaggcaa tctatgttgc
       61 catcgatgtg ttccgtaatc gtcagcggga aaaagtggct cgtgccaatc cgttgcgtaa
      121 acagtattac gagaaacgtg acgatagtga taaactgaag ctggatacag tagacgaaga
      181 ttaaaaacga gtgatgacga aagcagagat acaacaagtg aaacagcgtt ttggtattat
      241 tggaaatact gaagcattgt cgcgcgccat agatgttgcc attcaggtag ctcctaccga
      301 tttgtctgtg ctgattaccg gagaaagtgg agtcggaaaa gaaagttttc cgcagattat
      361 tcatcaatat agccggagga agcacggaca gtatattgct gtcaactgtg gcgctattcc
      421 ggaaggtacg attgattccg aactgttcgg acatgagaaa ggtgcgttta ccggtgcgat
      481 tggcgaacgg aaagggtact ttggcgaagc cgacggcggt actatttttc ttgatgaagt
      541 aggggagttg ccgatgtcta cccaggcacg tttgctccgt gtactggaga gtggcgagtt
      601 tatgaaagta ggttcgtcca aagtacaaaa aacggatgtg cgtgtggtgg cagctaccaa
      661 cgtcaatctg acacaagcga ttgcagaagg acgtttccgt gaagatttat attaccggtt
      721 gaatacggtg cctatccaga taccgccttt gcgtgaacgt ggtgacgatg tactcttgtt
      781 gttccgtaag ttttccgcag actttgcaga gaaataccgg atgcctgcta tccagttgac
      841 agaggatgcg aagaaagagt tgttggctta tccgtggccc ggaaacgtgc gccagttgaa
      901 gaacatcacc gagcaaatat ctatcattga aaccaatagg gagatctctg ctgctatctt
      961 gcagaattat cttcctgcac aaaatacgca acgtcttccc gcgctgatgg gaacgcgtga
     1021 gagtaaaggc tttgagagcg aacgggagat tctttattct gttctgttcg atatgcgcca
     1081 ggaagtggcg gagctgaaga agatggtgca caatctgatg gcggaacgtg ccggacaggt
     1141 ggggcaggta ggacaaatgg gaacggtggt tactactccg gtagtgacgg cgcatcaacc
     1201 ttcggtacct gctatcattc acaccatgca gcccacggtt tgcaaggatg atgatgacat
     1261 acaagacacg gaagaatatg tagaagaatc tcctttgtca ctggacgaag tggagaaaga
     1321 aatgatacgc aaagcacttg agaggcatca tggaaagcgg aagagtgcgg ccaaggactt
     1381 gaatatttcc gagcgtacac tttatagaaa aataaaagaa tatgaattgg attaagaaaa
     1441 taatacgccc tttgttactg ttcggcttgc cgttggtagt cattgcgtgc actgtttcct
     1501 ataagtttaa cggatcgtct atcaattatg ataaggtaaa gaccatttcg atagccgact
     1561 tcccgatcaa gtcggagtat gtgtatgctc cgttggcaac caagtttaat gaggacctga
     1621 aagatatctt catccggcag acccgtctgc aactgctcaa gccgagtcaa aatgccgact
     1681 tgcagattga cggagaaatc acaggttaca atcagtacaa tcaggctgta tctgccgacg
     1741 gttattcttc ggagacgaag ttgactatca ccgtcaatgt gcgttttgtc aacaacacca
     1801 atcatgccga agactttgaa caacagtttt ctgcgttccg tacctacgac tctagccagt
     1861 tgctgactgc cgtacaggac ggattgattg ctgaaatgtc taaagagatc accgaccaaa
     1921 tttttaatgc aactgtagca aactggtaat ataaatgact tctgttaact ttcaacaatg
     1981 gattcagcat cccgagacgc tgaataggga tactttgtac gaactgcgca atcttcttgc
     2041 gaggtatccg tattttcagt cacttcgtct gctgtatctg aagaatctgt atattctcca
     2101 tgatattagt tttggtggag aactgcggaa agcagttctt tacattgcag acagacggca
     2161 gttgttccgg ttgattgaag gtgaccgcta tgatgtgcag gcacggaaaa agggagtacc
     2221 tctcacggag gtgctgaaag acgaaccgtc cgtagaccgc acattagcat tgatcgacgc
     2281 tttcttgtcc acagtacccg aagaggtgac tgcccggacc agcttcgact attcgatgga
     2341 ttacacttct tatcttttgg aggagactcc ggccacggaa cagccggccg aagaaatgcc
     2401 caaactcaaa ggctacgaac tgattgacga ctttatagaa aagagcgaga gcgactctcc
     2461 cctctgcatg aaacctttaa gagaagaaat gccatcttcg ccaacctctt cggacgaact
     2521 taccgaagaa gaaacgatga aggaagaaga ggaagatgac agctgtttta cggaaacttt
     2581 ggcaaaaatc tatgttaaac agcaacgata ttcaaaagct cttgaaataa ttaaaaaatt
     2641 aagcttgaaa tatccaaaaa aaaatgctta ctttgcagac caaatcagat ttttggagaa
     2701 attgattatt aacgctaatt caaaataact aaaaatgtac ttattattcg ttatcttaat
     2761 ggttattgca gccttgttga tgtgtttcat cgtgctgatt cagaactcaa aaggaggcgg
     2821 acttgcttct ggtttctctt catctaacgc catcatgggc gtgcgcaaga ctacagattt
     2881 tctggaaaaa gcaacatggg gcttagctat cttcatggtg gtaatgagca ttgctactgc
     2941 ttatgtagtt cctcgctctg ctgttgctaa agacgcagtg ttggaacagg cacagaaaga
     3001 acaacagact aacccgtata acttacccgc aggtacggct gcgccgcaaa ctgaagctcc
     3061 tgctaccaat gcacctgcta cagaaactcc ggcaccggct gctgaaactc ctgctcctgc
     3121 agcagagtaa ttcactccgt cgtcaggtaa gactttgggg taaaaccatt aatgggaagg
     3181 tgcagacgga tgctgcattt ctttgatatt taagtgcgga ttacgcagat tacacggatt
     3241 ttcaatcttc cgcgtggtca gtgtaatccg cacttaactt tttcttgtaa aaacaatctc
     3301 tttttgatag aaacaaacga gatttaacta cctttgttgg tcgtatgaag attattaact
     3361 actattttta aatatagcaa tgacagaaca tttgaaacag aaattgaatg actccgccgt
     3421 actccgatgg agtgttctag cattagtcgc atttactatg ctatgcggct atttcctcac
     3481 cgacgtaatg tctcctctaa aacccatgct tgagaaagaa ctactatggg acagtcttga
     3541 ttatggtttc ttcacaagtg cttacgggtg gtttaatgta ttcctattga tgctgatttt
     3601 cggtggtatc attttggata agatgggagt tcgtttcacc ggaatgggag cttgcttatt
     3661 gatggtgttt ggttgtggat tgaaatacta tgcgatttct actacttttc cggaaggtgc
     3721 catgctcttt ggattcaaaa cacaggtaac cctggccgca ttggggtatg ctatcttcgg
     3781 tgtaggtgtg gaaattgccg gtatcacagt ttccaagatt atcgtgaaat ggttcaaggg
     3841 taaggaaatg gcattggcta tgggacttga aatggctacg gcacgtatcg gaacaactct
     3901 ggcaatggtg cttacggttc ctttggccga ctttttcgga tctacggatg agagtggcac
     3961 attccatacc aatattcctg ctccgatttt gttttgtctg attatgttgt gcgtgggtac
     4021 gattgctttc ttcctttata ctttctatga taagaagttg gatgcttctt tggatgcaga
     4081 gggattggaa ccggaagagc cgttccgtat gaaagatatt gtgtatatca ttaccaataa
     4141 aggattctgg ttgattgcat tactatgtgt attgttctac tcggctgtat tcccctttat
     4201 caagtatgct gccgacttga tggtgcagaa gtataatgta gatccgaagt tggcgggaac
     4261 gattcccgga ttgttgccga ttggtgcgat tatcctgact ccgttgttcg gttcgcttta
     4321 tgaccgtatc ggtaagggag ctacgttgat gataatcgga tcagtgatgc ttatttttgt
     4381 gcatacgatg tttgctctgc ctatactgaa tatatggtgg tttgctacta ttatcatgat
     4441 tatattggga tttgccttct cgttggtgcc ttcagctatg tggccgtctg ttccgaagat
     4501 tattccggaa aaacagttgg gtaccgcata cgcattgatt ttctgggtac agaactgggg
     4561 attgatgggt gttcctttgt tgatcggatg ggtgttgaat acttattgca aaggtccggt
     4621 agtagacggt gcacagactt atgactacac gttgccgatg gctatttttg ctctctttgg
     4681 tgtgcttgct ctggttgtgg ctttgatgtt aaaggcagag aacaagaaga aggaatacgg
     4741 tctggaagag gcgaatatcc aaaagtaact aggaaattca atacctaaag tgacaaagga
     4801 attttgtatc aaggtgtaaa cagaagagta tcagtatgaa tactctgaaa taaaaaataa
     4861 gaagtatggc tgccaaagag aaaatcaacc tgttagaggt cattccctgt cgcagtgaac
     4921 atattacagc agaaagggaa ggggagacaa ttgtgctctc ctttccccgt tttaaatatc
     4981 cgtggatgca acgcttcctt gtgccgaaag gaatgtcgaa agaacttcat gtgaaattgg
     5041 aagaacacgg tacggctgta tgggaactga tagatggaaa acgcaatgtt cgtgagatta
     5101 tagaaaaact cgcagaccac tttcaaaatg aagagggcta cgagtcgcgt gtatcggctt
     5161 atctttctca aatgcagaaa gatggattta taaaactggt gataccagtc gcataaatag
     5221 gaacttatta ttatttattt gataaataca gcccaaagta tgacggcaat tgctatcagg
     5281 actcccatga taataagcgt tccccaaaca aaataattgc tgtctttctc tttctttttc
     5341 tccgagtcgt ggatgatacg ttccatttct tcgggggtgg tgttgggtag tggataaggt
     5401 tcgtttgcac ggtttagatg cttcaactta tcgttagcac gttcacgacg taggcgggaa
     5461 gcttcccgtc cctcttttat tcggcgtatc atgtcgaatg catgtccttc accaaccata
     5521 ttctttgttt tttagaagtt cacttccttg tttttctatt tcccttcttc tctgtccact
     5581 ttgagcaatc ctcccgtatt cggatcaaaa taaactttga tggtagaatt cttattgaac
     5641 aaaaccggag ccagatattc tatcacaccg aattgagtaa taggaagctc accttcgtaa
     5701 agtttctttt taccgtcggt cagtgtaacc atagcttgtc cgggtacgtt gtaggcgatt
     5761 ccatctaaat ctttcttctt cttaccatct tcctgtggca tcttgaccga tttcaggtct
     5821 ttcagactga tataaaacgg agttcctgcc aaatcattgt tggcaactac acctaacttc
     5881 ttcgagaagc ggaaagcaac ttcattgttg aattccttgt caggggtaag gcggacagtg
     5941 aatgttctct cttctttgtt gcaggtgccg gagaacattt gtgtcatggc ttcttcctgt
     6001 gcattcagat tgtcgagcat aattttaagc tgtgccccgt ctgaaggcat attgtcagcc
     6061 tgtccgcgca ataaggcatt tttgctttcg cggatgttat agatttcttt agccaccagc
     6121 tcggccatct tggcggtaga actagccatc agaatctctt cggtcaggaa ttcgcgagga
     6181 ttcgctttct tttggaggac tgcgggagcg ggagcagttt ttttgcctac actgctattg
     6241 ctgtaaggaa cattgatcgt tttcacaatg ccatcctctg tcagttccat gagcggtgct
     6301 actgtcttat ccttcaattt tacgaaatac gtagtttcgc tgttgggcac acctacggat
     6361 ttcactttta cgctagccag ttcccagtac tcttcagggt cggcggagac gttggtcagt
     6421 cgcaggtaac gatcagcata tttgctgaat tctcccggag tatagttgac tttgttggct
     6481 tttatttcaa gttctatttg ggttttggga agactgtaaa ccactccata gtcttttcct
     6541 cgggtaaccc ctgtcagtac ttcggtttgt gcataggcgg acgttgtcat aagtagtcct
     6601 gctgctataa ttaacttttt catattcggt tcttttttaa ctggttttga aaacaaagtt
     6661 aatgaagtta ttgaaaaaac tgtaagttct taacttttat tcgcttacaa gtcgccatgc
     6721 tgtcggcaga caggtgataa tatcgcttgc gatcattccg atcattcctt gcttcttttg
     6781 agcgacatcg cccgccaatc cgtgaatgta agtgccgatt ttagcggctt cttcggtggg
     6841 ataaccttgg gcaagcagtg ccaggattac tccggtcagt acgtcaccgc tacctccggt
     6901 tgccattccc ggatttccgg ttgggttgaa gaaacattta ccttctgggg tgataatggc
     6961 ggaataggct ccttttaaaa taatgtgaac atgggcggca cgagccaatt cgcaagcctt
     7021 catcagacgt tcgtaagagt cttggcattt gccggtcaga cgttccagtt ctttcggatg
     7081 cggggtgagg atggaaccct tcggcaggtg ggtaagggta tggcggtggt tggcaaggat
     7141 attaagtgcg tcggcatcca ctacaacagg agtctggcaa tgttccagtt gctccaataa
     7201 ggcagcttcc gtttcctcgt ttcgtcccag tcccggaccg atgccgactg cttgatagtc
     7261 gtccgtgtcg gtaggtacgg caaaacaggt ttcgttgatg tcggtttcta cgattgcttc
     7321 gggtatggag gtctgcaaga tgtcgttgtt gcacattggt gcatgaacag tcagcaaccc
     7381 tactcccgaa cggaggcagg cacgggcagc gagaacagag gctcctgcca ttccttttga
     7441 accggcaatc aatagtgcat gaccgaagtt tcccttgtgg gcaaactgtt tgcgtggctt
     7501 gatgagtgaa cggatttgct ctatttccaa catttcgtag ttcgtttcca tctcttcaat
     7561 accgtcttcg ctcaattgga tatccaacaa ttcccattct ccgacaaatt ctgtgttttc
     7621 tgcgaaaaga aaggcgagct tcggcagttg cagactgaaa gttacgtcgg cacggataat
     7681 attagctttt acgttgaatg tattttcttc tcccatcagt ccggaaggga tgtcgatggc
     7741 tactaccatg gcaggggagg aattgatgta tttcactacg gcagcgaatc cgccgctcaa
     7801 cggtttgttc aggcctgaac cgaataatcc gtcgattacc agatggtcgg gcgtcagggc
     7861 gggaggtacg aattgggtac tgatctcgtg gaattttact tcttccatca tttctaccag
     7921 ttctttattg gtctggcagt cgggtgaaag ttctcctttc gtgttgaaga gaaatacctc
     7981 gattttatat cctttttcag ccatcatgcg ggctacggcg agagcgtctc cgccattatt
     8041 ccccggtccg gcaaagatag tgaccggcgt ttccgtattc catctgtctg tgatggcttt
     8101 tgttaatacg gttgctgcac gttccatcag atcgattgat gcaataggtt cgttctcaat
     8161 ggtataagcg tccaatttct tgatactgct gcttggaaat attttcattg cgatgttctt
     8221 ttagttttcg gattacaaat gtacatgatt cttctgactt ttcccgtttg ttgtgggaag
     8281 aaaaccataa ttgcaacttt taattcatca ttagttctat ctttgggtca gagaaatatc
     8341 tgcttttgaa ctattaagtg ttagaataac tccgccaaaa aataattcaa tgcagcacca
     8401 ttatgaactt acttttattt ctcctgaaaa agatttcttc atttcatttc tcatattctc
     8461 attgtttttc gataaacgaa agctaatcaa atagatatct tatgagaaac actttttcga
     8521 aacggtattt ctcataagtt ctcccatatt ttggctcaaa agccgcctta ttctcatagt
     8581 atttcagggt atttctcata gtcaaaagcc atttgttctt ccttttttct ttcagcctgc
     8641 cttattttta tcaggaaatg aagctactat ttagataaaa tagtggcttt ttgcttgaag
     8701 atgctcattg gtctcgattg tcccatatat tgtgggaaag ttttccttca atatacggga
     8761 atactttccc acaaaataag ggaatacttt cccaagcctt agggaatctt ttcccacaat
     8821 atgtggaact aagacactgt gtatggaagc aagcaaaagg aatacatagt tttatttatt
     8881 caatgtcagc ttccggcaca ctacactatg agaaatgaag caaaatccgg gttattttgc
     8941 gaagaaacta tgagaaatac ctgttttaaa atcatttctc atagcctatc ttattagttt
     9001 actgccactt gtttcttatt tatgagaata tgagaaatga aaaatctttt tctgtagagg
     9061 cgcggatgga aattgtgttt agtttatcgc cataccttct taaacaaatt tttaatgcgg
     9121 ttccccttat taagcctttg attatttgcc gtttccgata aaaatgttat ctttggagat
     9181 agataatgtg catcacatca ttttccagtg ctcacaatga aaatgaatta aaatctaaat
     9241 aacggattgt ttaatcttct aaagtttgca tgatggaaaa gacaaaaatt ggcttgaatg
     9301 ccgggaaagt atggcgcatc ttaaatgaaa aaggtgaact ttcaatgttc gatttgtgcc
     9361 gtgaattaag tttgacgttt gaagacgtag ctctcgctat tggttggctg gcccgagaag
     9421 acaaaatctt tttgaggaaa agagaaggaa tgctttttgc cagtatcgaa aatgtcgaat
     9481 ttacttttgg ctaaggtggt agctaaccta catttaagat ggatctccac tttattattt
     9541 acactgctaa aaaagtaatg aagtggatca gtaggatttt ttatgctcgt ttttactatt
     9601 ccccctatta ttctgtttga taagagaagc atctaatcta ctttttctgt acctttgcac
     9661 cccataaact actaaacaca taaattcatg agtgcattga aagggcatcc gaaaggcctt
     9721 tatctgattt tcgcgacaag cacggcagaa cgtttcagtt actacggtat gcgtgcgatc
     9781 tttattcttt tcctgacgca ggcattattg tttgataaag aagcggcagc atccatctac
     9841 ggcagctata ccggactagt ttatttaacc ccgttgattg gcggatacat tgccgataaa
     9901 tattggggaa tccgtcgctc cgtgttttgg ggagcggtaa tgatggcagt cggacaattc
     9961 ctgatgttta tgagtgcttc cactttagat aatacaaacc ttgcccactg gatgatgtat
    10021 ggcggactag gcttcctgat cttgggcaat ggttgcttca aacccactgt ctcttctctg
    10081 gtaggtcagc tctacgaacc cagagacagg cggctggatg ctgcatacac cattttttat
    10141 atgggagtga atgtaggctc ttttgctgct cctttgattt gtggttatct gggtgatacc
    10201 ggtgatccgc atgactttaa atggggattt cttgcagccg gaatcatgac actgttcacc
    10261 gttgttcttt tcgagactca aaagaataaa tatctttttt ctccttccgg agaaccgatt
    10321 ggtattatcc ccgatgctaa acgtgaaaag aaagaagaca aggccgacca tatctcacac
    10381 ccgaagatgg acaaacgtac caaagtacgt aatacccttg taatcacaat tcttaccatt
    10441 gctttaatag ccttctttaa ctatgcattt gaaggcgatt gggtgagtat cggcattttt
    10501 accgcctgca ttgttttccc tgttctgatc ctgttagacg gttcattgac aaaaatagaa
    10561 cgcagccgta ttttcgttat ctatatagta gccttctttg tcatcttctt ctgggcagcc
    10621 tacgaacagg cgggagcttc tttaactctc ttcgcatccg aacagacgaa tcgtgacata
    10681 ttcggttggg aaatgccggc ttcatggttt caatccttca atccactgtt tgtagttgtt
    10741 ctggcatata tcatgccggg tgtatggggt ttcctgaaca agcgaaagat ggaacctgct
    10801 tctcctacca aacaagcgat tggtctgtta ctcctttctt taggttatct tttcatctgt
    10861 ttcggagtga aagatgctgt tcccggagtg aaagtgagca tgatttggct gacaggactt
    10921 tactttattc atactatggg tgaaatagct ttgtcgccta tcggactttc aatggtaaat
    10981 aaattgagtc cgctgcgttt cgcctccctg atgatgggaa tctggtatct gtctactgcc
    11041 acagccaata aatttgcggg aatgttgagc gggctctatc cggaagccgg aaaagtgaag
    11101 tcaatctttg gttatcagat tgctaccatg tatgatttct ttatggtatt cgtcgtgatg
    11161 tccggtgttg cttcgttgat tctgttcctt ctctcgaaga aattacagaa gatgatgcac
    11221 ggggtagaat aaaaaatcgt atttttgcaa ggttattttt aaattaccgg ttatggatac
    11281 cattcagata aaagacaaat tgtttaccgt ttccattaag gaacaagaaa ttcagaaaga
    11341 agtgattcgc gtagcgaacg aaatcaaccg cgatttggca ggtaagaatc cgctttttct
    11401 tagtgtgttg aacggttcgt tcatgtttac cgctgattta ctgaagcaca tcaccatccc
    11461 ttgtgaaatc tcatttgtga agttggcgtc ttatcagggc atcacttcca ccggagtgat
    11521 taaagaggta atcggcctga atgaagacat tgccggacgt accattgtga tcgtagaaga
    11581 tatcgtagac acaggactga cgatgcagcg attgctcgaa acattaggta cacgcaatcc
    11641 tgaagctatt catatcgctt ctctgttggt aaaacctgaa aagctcaagg taaacctcaa
    11701 cattgaatat gtagcgatgg aaatcccgaa cgactttatc gtaggttacg gcctggatta
    11761 tgatggtttc ggacgtaatt atcccgatat ttatacagta gtagattaat attaaatagg
    11821 taccagttta aatggtaaat agtaaatcgt taaattgtaa ataacaaaat gttgaacatc
    11881 gtaattttcg gtgctccggg ttcaggaaaa ggaacacaga gcgaacgtat cgtagaaaag
    11941 tatggaatca atcacatctc gacaggagat gtattgcgtg ctgaaatcaa gaatggcaca
    12001 gaactgggta aaacagctaa aggttacatc gaccaaggtc aattgattcc tgatgaatta
    12061 atgattgata ttctggcaag tgtattcgac agcttcaaag atagcaaagg tgtaattttc
    12121 gacggtttcc caagaacaat cgcacaggca gaagcattaa agaaaatgtt ggcagaaaga
    12181 ggacaggacg tttctgtaat ggttgacttg gatgttccgg aagaagaact gatggtacgt
    12241 ctcattaaac gtggcaagga ttccggtcgt gctgatgata acgaagagac aatcaagaaa
    12301 cgtctgcatg tatatcattc acagactgct ccactgatcg actggtacaa gaacgaaaag
    12361 aaataccaac acatcaacgg cttgggtact atggaaggta tcttcgctga aatctgcgaa
    12421 gcagtagata aattgtaata atacaatatt ataaataaat aagtcagtag ccggagtgtt
    12481 ctaattaact gctctaacta ctgactactt taactcttta aaaaaatatg gctgaatcga
    12541 attttgttga ttacgtaaag atatactgtc gctcgggtaa gggcggaaga ggctctacgc
    12601 acatgaggcg cgagaaatat tgtcctaacg gaggtcctga tgggggcgat ggtggaagag
    12661 gaggtcatat catcttgcgc ggtaaccgta attactggac attgctgcat ttgaagtatg
    12721 accgtcatgc aatggccggt catggtgaat cggggagcaa aggacgtagt ttcggaaaag
    12781 acggtgcgga taaaataata gaagtaccct gcggaacggt agtttataat gccgagacag
    12841 gggagtatct ttgtgacgta acagaagacg gacaggaagt ggtcttgctc aaaggcggcc
    12901 gcggcggtca gggtaactgg catttcaaga cggccacccg tcaggctccg cgttttgcgc
    12961 agccgggaga accgatgcag gaaatgaccg ttatcatgga gctgaaactg cttgccgatg
    13021 ttggtctggt aggtttcccg aatgcgggaa agtcaacttt gctttcttcc atttcggccg
    13081 ccaaaccgaa aattgccgat tacccgttta ctacactcga acccaacttg ggcatcgttt
    13141 cctatcacgg tggaaaatcc tttgtgatgg cggacatacc gggtattatc gaaggtgcta
    13201 gccaggggaa aggtttggga ctgcgtttct tgcgtcatat cgagcgtaat tcattactgc
    13261 tgtttatggt tccggcagac agcgacgaca ttcgtaaaga atatgaagtc ttgctgaacg
    13321 aactgcgtac cttcaatcct gaaatgttgg acaagcaacg tgtgttggct gtcaccaaga
    13381 gtgatatgct cgatcaggag ttgatggacg agattgaacc tacattgccg gaaggcattc
    13441 cacatgtatt catatcttct gtttccggtt tgggtatctc ggtgttgaaa gacatccttt
    13501 gggaagaact gaacaaggaa agcaataaaa tagaggacat cgttcaccgt ccgaaagacg
    13561 tgacccgtct gcaacaggaa ctcaaagaca tgggcgaaga tgaagacatc gtttatgaat
    13621 atgaggaaga tggcgacgat gatatcgatt atgagtacga agaagattgg gaagaagaat
    13681 gatttctctt acaaaacata acgagttgaa gggatataag tcattagatg catatcccga
    13741 agtagctcat ttcgtaacta cacgtcacgg aggtataagc accggagctt acggctcttt
    13801 caactgttcg ccttatacca acgactcatg tgtgaacgtc aatcgcaatc agaactggtt
    13861 gtttcagtgc atgaatcatc agataaagga attatttatt cctgaacaga gtcatggttg
    13921 cgccagtctg attatcaatg aatcattttt taaagaatca ttggaaagga gacggctact
    13981 tctgcgagga atggatgctt tgataacgaa tgtgccggga tattgcgttt gtgtcacgac
    14041 agcggattgt gttcctgtat tgctgtacga caaaaaacaa cacgttgtgg ctgccgttca
    14101 tgccggatgg aagggaacgg tgaagcatat tgtcagtcat gtgatggaca acatgactca
    14161 aaagttcggg acgcaaggcg aagatgtaat agcttgcatc gggccgagca tttcgctcga
    14221 atcatttgaa gtaggcgatg aagtgtatga tgcttttgaa gaaagcggtt tcgatatgtc
    14281 tcttatttct atgaagaaga aggagacagg caaatatcat attgatttgt gggaagccaa
    14341 ccggattgaa ttactgaatc gcagagtgcc tgcagagcag atagaagtgg ctggaatctg
    14401 tacctatatt catcatgatg aattcttctc cgcacgtaga ctgggaatag attccggtcg
    14461 tacattgtcg ggaataatga ttagaaagta ataattggtg tccgttattg caggacgctg
    14521 atgattggtt tatgataagt tatgtttgaa ataaaagtat ctaaagaaat aaaagacgca
    14581 tgtccggttt ttgccggagc cgctgtgtat gctgttgtga aaaatacagc ttacagcgaa
    14641 gggctttggc aggaaatcga cgcttttacc aagcaactga cttccacaac acagatggaa
    14701 gacatcaaac atcaacccgt tatctttgct acccgtgagg cttataaacg ttgtggcaaa
    14761 gaccccggac gttaccgccc gtcagccgaa gctctacgcc gccgcctgat gcgtggaatt
    14821 cctttatatc agattgatac gttggtagac cttatcaacc ttgtgtctct tcgtacggga
    14881 cattcgatcg gtggttttga cgcggacaaa atacaaggta cgcatcttga actcggtatc
    14941 ggcaaagcag gagaaccgtt tgaaggtatc ggacgcgggg tattgaatat cgaaggatta
    15001 cctgtatatc gtgattcttt cggcggaatc ggaaccccga caagcgacca tgaacgtacg
    15061 aagatggacc tcgaaactac tcatatccta gccatagtca acggttataa cggaaaagaa
    15121 ggtttgcaag aagctgttga aatgatacag accttattaa gaaactatac agaatcggat
    15181 ggaggcgaaa tcgtattctt cgaataatta gaatga
//
