LOCUS       c00020_gnlPro..        14931 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ODHLNHLJ_20.
ACCESSION   c00020_gnlPro..
VERSION     c00020_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 23:37:59
            Original ID  :: gnl|Prokka|ODHLNHLJ_20
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14931
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14931
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7884:10857]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7885..10857
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..14931
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14931
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(217..2985)
                     /locus_tag="ctg20_1"
                     /transl_table=11
                     /translation="MRQILLGLCLLCLLNNVSGQENGREIPLPEKMPQEHPRVLTTPDG
                     KQDTWELIKKEKWAKDVFNKLKERTEVYTNLTDAQPAWLLSRLAMSWKSHATELYVKGE
                     TYDHAGGEKAPYPTVRYTGTRGTAATHGRPKLADVVPYDDDENGNVTFCNNALPERPLE
                     SVHPSKTGRNIESLNREILGIACDAAFLYWMTDEEKFAKLAAGVFDTYMTGIYYRNVPI
                     DLNHGHQQTLVGLTSFEVIHEDALHIVVPLYDFLYNYLKTNYPEKMDIYAGAFKKWADN
                     IIANGVPHNNWDLLQARYIMNVGLVLEDNKEYADGKGREYYIDYVLNRSSIRQWSLTRL
                     ADYGFDSTTGIWAECPGYSSVVINDYANFANQFDNNLKYDLVKAMPVLSKAVAATPQYL
                     FPNRMICGFGDTHPSYLNTNFFIRMIQNAQANGKTEQENYFTALLKCLNPEIDNEKGEK
                     NNVRVSVNSFFEDKPLSLNPKVKAGKIEDYVSPLFYAPNVSWLVQRNGMHPRHSLMISL
                     NASEGNHMHANGISMELYGKGYVLGPDAGIGLTLYSGLDYAEYYSQFPSHNTVCVDGIS
                     SYPVMKSNHSFDLLSCFPASAEPGKEFTSVTYSNVYFREPESRADQTRMMSIVTTGSET
                     GYYVDVFRSRKERGGDKMHDYFYHNLGQTMTLTAADGTDLNLQPTEELAFAGAHLYGYS
                     YLYDKKVAATGKDVKATFTIDMKDKGGDDIVMNLWMKGEPDRDVFTALSPMTEGLSRTP
                     GMPYNIKEQPTLTFVVRQHGEAWTRPFVAVYEPSTKKEPSAIQSVSYFDVEETVLKDFA
                     GICVKSKNGRIDHIFSLSDATQTATYQGMKVKADYAVVSNEYAGNRTLFLGNGTQLVAP
                     KVTVHTDQAGNVLLEKKQGKWYILSSVPCTVVINGKKIKSGITSQLTLLPV"
     CDS             3075..5054
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH_4Fe-4S"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_2"
                     /sec_met_domain="Fer4_7 (E-value: 1.7e-10, bitscore: 31.2,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 4.2e-11, bitscore: 32.4,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.2e-50, bitscore:
                     161.1, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00031, bitscore: 11.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 2.2e-12,
                     bitscore: 36.8, seeds: 130, tool: rule-based-clusters)"
                     /sec_met_domain="NADH_4Fe-4S (E-value: 2.9e-34, bitscore:
                     106.6, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPERYFYSNKELYLQKNRLTILILMKILSIHDLATIRKRAEHNLS
                     LREESNEKVTEKCYGLASGAQHLQILICGGTGCKASSSQGITDNLLKAIQKNEITDKVE
                     VITVGCFGFCEKGPIVKIIPDNTFYTQVTPEDAEEIINEHIIGGRRIERLLYVDPKTEH
                     TVSDSKHMDFYRKQLRIALRNCGFIDPENIEEYIAREGYFALADCLLNKQPTDVIDIIK
                     RSGLRGRGGGGFPTGLKWEFANKQQSDVKYVVCNADEGDPGAFMDRSIMEGDPHSIVEA
                     MCVCGYSIGSTKGLVYIRAEYPLAINRLKTAINQAREYGLLGDHILGTDFSFDIEIRYG
                     AGAFVCGEETALIHSMEGKRGEPTLKPPFPAESGYLGKPTNVNNVETLANIPIILTKGA
                     DWFATIGTERSKGTKVFALAGKINNVGLIEVPMGTTLREVIYEIGGGIKGGKKFKAVQT
                     GGPSGGCLTEKHLDTPIDFDNLLSAGSMMGSGGMIVMDEDDCMVSVARFYLDFTVEESC
                     GKCTPCRIGNKRLLELLNKITEGKGTEKDLDTLATLGQVIKDTALCGLGQTSPNPVLST
                     LDNFYDEYMEHVRDKTCRSKQCKSLLTYTISPERCIGCHLCAKNCPADAISGLVRKPHV
                     IAPDKCIKCGMCMARCKFNAILVC"
     CDS             5066..6832
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH-G_4Fe-4S_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_3"
                     /sec_met_domain="Fer4 (E-value: 3.3e-10, bitscore: 29.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2e-05, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_4 (E-value: 2.5e-23, bitscore: 71.7,
                     seeds: 126, tool: rule-based-clusters)"
                     /sec_met_domain="NADH-G_4Fe-4S_3 (E-value: 2.4e-19,
                     bitscore: 58.4, seeds: 418, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDKQITLQIDGHFITVPEGSTILEAATKIGINIPTLCHIDLKGT
                     CIKNNPASCRICVVEVIGRRNLAPACATRCTEGMVVKTSTLRVMNARKVVAELILSDHP
                     NDCLTCPKCGNCELQTLALRFNIREMPFNGGELSPRKREITASIVRNMDKCIFCRRCES
                     VCNDVQTVGALGAIRRGFNTTIAPAFDRMMTESECTYCGQCVAVCPVGALTERDYTNRL
                     LDDLANPDKVVIVQTAPAVRAALGEEFGFPPGTLVTGKMVYALRELGFDYVFDTDFAAD
                     LTIMEEGSEILNRLTRYLNGDKSVRLPILTSCCPAWVNFFEHHFPDMLDIPSTARSPQQ
                     MFGSIAKSYWAEKMGIPREKLVVVSIMPCLAKKYECARDEFKVNGIPDVDYSISTRELA
                     RLIKRANIGFPLVLDSPFDNPMGESTGAGVIFGTTGGVMEAALRSVYEIYTGESLKNVN
                     FEQVRGLNGVRRATINLNGFELKVGIAHGLGNARHLLEDIRNGHNEYHVIEIMACPGGC
                     IGGGGQPLHHGNSEILYARANALYREDANKPLRKSHENPYIKTLYEEYLGKPLGEISET
                     LLHTHYFNKSMD"
     CDS             6851..7327
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_4"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 6e-55, bitscore:
                     174.8, seeds: 130, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDIKLACDVAEQVRTICDKHGNNPGELINILHEAQHLHGYLPEE
                     MQRIIASKLNIPVSKVYGVVTFYTFFTMTPKGKHPISVCMGTACYVRGSEKLLEEFKRV
                     LGIEVGETTPDGKFSLDCLRCVGACGLAPVVMIGEKVYGRLQPIDVKKIIEELE"
     CDS             7885..10113
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_5"
                     /sec_met_domain="Gly_radical (E-value: 5.1e-47, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1171.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEVKKEDLRNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             10129..10857
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 73.2;
                     E-value: 8.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_6"
                     /sec_met_domain="Radical_SAM (E-value: 6.4e-30, bitscore:
                     94.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLMRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(10929..11375)
                     /locus_tag="ctg20_7"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRADRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDENGKAADTRTSRQKEAMHRLVSELL
                     QRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIEEFES"
     CDS             complement(11362..11529)
                     /locus_tag="ctg20_8"
                     /transl_table=11
                     /translation="MKEIVTKILDVIMFLVPFFGKRKRNRIVREVRFNATHKEVCNVKT
                     TEREKDDEKD"
     CDS             complement(11550..12053)
                     /locus_tag="ctg20_9"
                     /transl_table=11
                     /translation="MAMTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITS
                     RSTCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLIT
                     AAHIIFRPGKTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAP
                     DPAA"
     CDS             12247..12477
                     /locus_tag="ctg20_10"
                     /transl_table=11
                     /translation="MYYPDQPFHIRTYKKSELAHLYNPNVCLKVALQILRRWIVYNLPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             12565..14682
                     /locus_tag="ctg20_11"
                     /transl_table=11
                     /translation="MEHFTIFQDFYRVIAEMTEEEIVSAISNGTYRETVEDVRRIFAEQ
                     GEKAANEKKIELPEITFSANYRGGRSNATLVKYLGYIVVDIDHQTQEALARILALAKKC
                     AHTRIAFISPKGMGLKIVVRVCRTDGTLPETIQEIEDFHHAAYHKIASFYAQLCGVEVD
                     TSGQDVSRTCLFSYDPDIYFNPDATAVIVEQPPMFFKSQKKKRASGKKKKTTAPDNNPL
                     TEQVALNYHSSHASLMVTLNYYHNKSEKYVTGNRNNYLHCLACMYNRYGVPQEEAAAFI
                     KSQFTDLPADEMDALIGSAYGHNEEFDTRKLNSTQKRILQIEQHIKENYDTRYNEVLHI
                     MEYRRRKTDTEQPEPFHILDEMMENSIWMEMNELGYSCTVKTIQNLIYSDFSSTYHPIR
                     EYLDSLPEWDGTDYIGILANSVHTSHQKFWVECLERYLVGMCAAATQDDVVNHTVLLLC
                     SEIQNIGKTTFINNLLPPELRAYLSTGLINPNNKDDLAKIAQAMLINLDEFEGMNGREL
                     NIFKDLVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVDSME
                     FIKINYAQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPE
                     RFEKVHYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIID
                     TEQVKSNRLYE"
     CDS             14797..14931
                     /locus_tag="ctg20_12"
                     /transl_table=11
                     /translation="MLEIYPHLPSPFPFSSSKKRGCVKTLTQPFFYAQSPDFLKPGLCY
                     "
ORIGIN
        1 tgatagcaca gcccctagcc tgcaaccatt ccgcattaca tacatcataa tttatttccc
       61 actaaatatt tcccactaat acttacccat aaaaagggct ttctgtctgt ttcccttaaa
      121 catcagacag aaagccgcaa atttagaaaa aatatggcat ttaaaacgtt tgaatacgtt
      181 tttttattgc atttttttca ttcaaaatca ttttaatcag acaggcaata acgtgagttg
      241 cgatgttatt cctgatttta tcttctttcc attaataacc accgtacaag gaacagaaga
      301 aaggatatac cattttccct gtttcttttc gagtaacaca ttgcccgcct gatccgtatg
      361 aacggtcacc ttgggtgcaa caagttgtgt tccgttcccc aggaataaag tccggtttcc
      421 tgcatattca ttgctgacaa ctgcatagtc tgcttttact ttcattcctt gataagtggc
      481 ggtctgcgta gcatcagaca aggagaaaat atgatctata cgcccatttt tgcttttcac
      541 acagataccg gcaaagtctt tcaaaacagt ttcttccaca tcaaaatagg atacagactg
      601 aatggcagac ggttctttct tcgtacttgg ttcatagact gcgacaaaag gacgagtcca
      661 cgcttctcca tgctgacgga ccacgaaagt caatgtcggt tgttctttta tattatatgg
      721 cataccaggt gtacgactta aaccttcggt catcggtgac aaggccgtga aaacgtcacg
      781 atccggttcc cctttcatcc agagattcat tactatatca tccccacctt tatctttcat
      841 gtcgatggta aaggtcgctt ttacatcttt accggtagcc gctactttct tgtcatataa
      901 ataagaataa ccatacagat gcgctccagc aaaagcgagt tcttctgtcg gttgaagatt
      961 caggtctgta ccatcagctg ctgtcaatgt catggtctgt ccgagattat gatagaaata
     1021 atcatgcatc ttatcccctc cacgctcttt ccggctccgg aatacatcca cataatatcc
     1081 tgtctcggag ccagtggtaa caatgctcat cattcgggtc tgatccgccc tgctttccgg
     1141 ttcacgaaaa tagacattgc tgtaagtcac agaagtaaac tcctttcccg gttctgccga
     1201 agcaggaaaa caggaaagca agtcaaaaga atgattgctt ttcattaccg gatagctcga
     1261 tattccatct acgcatactg tattgtgact tggaaattga gagtaatatt cggcataatc
     1321 caggccgcta tacaaagtca gaccaattcc tgcatctggc ccaagcacat atccttttcc
     1381 ataaagttcc atggagatgc cgttagcgtg catgtgattt ccctcactgg cattcagaga
     1441 aatcatcagg ctatgacgcg gatgcattcc gttccgctgc accagccatg acacattggg
     1501 agcatagaat aaaggagaaa catagtcctc tatcttccct gctttcactt tcggattcag
     1561 acttaacggt ttatcttcaa agaaagaatt gacagataca cgcacgttat tcttctctcc
     1621 cttttcatta tcaatttcgg gattcaagca tttcagcaaa gcagtgaagt agttctcctg
     1681 ttccgtctta ccgtttgcct gcgcattctg tatcatgcgg ataaagaagt tcgtattcaa
     1741 atagcttgga tgcgtatctc cgaacccaca aatcatccgg ttgggaaaaa gatattgcgg
     1801 agtggctgcc actgctttcg acagtacagg catagccttt accaaatcat atttcaaatt
     1861 attatcaaac tgattggcaa aattagcata atcgttgatt accacactgc tatatcccgg
     1921 acactctgcc cagataccag ttgttgaatc aaagccataa tcggcaagac gagtcagact
     1981 ccattgacgg atactggaac ggttcaacac ataatcaata taatattcac gtccttttcc
     2041 atctgcatac tctttattat cttcaagcac cagtcccaca ttcatgatat atcgtgcctg
     2101 caataaatcc cagttattat gagggactcc attcgcaatg atgttatccg cccatttctt
     2161 aaatgcaccg gcatagatgt ccatcttttc cggatagttg gtcttcaggt aattataaag
     2221 aaaatcatac aagggaacaa cgatatgcag ggcatcttcg tgaatcactt caaaagaagt
     2281 caatcccacc aatgtctgtt gatgaccatg attcaggtca atgggaacat ttctgtaata
     2341 aattccagtc atatacgtat caaacacacc ggcagccagt ttcgcgaatt tttcctcatc
     2401 tgtcatccaa tagaggaaag ctgcatcaca agctattccc agaatttccc ggttcagact
     2461 ttcgatattc cgtcccgttt ttgacggatg tacactttcc aaaggacgtt ccggcaatgc
     2521 attattgcaa aaagtcacat ttccgttttc gtcatcgtca taaggcacta catctgccag
     2581 tttgggacgg ccatgagtag cagccgttcc acgtgttcct gtataacgga cagtcggata
     2641 aggagctttt tcgcctccgg catgatcgta agtctcacct ttcacatata gctcggttgc
     2701 atgagatttc caagacatgg ccagacggga taataaccat gcgggttgag catccgtcag
     2761 attggtatat acttcggttc gttccttcaa tttattgaat acgtctttcg cccatttctc
     2821 ttttttaatc agctcccacg tatcctgctt tccatccggt gtagtcaaca ctctcggatg
     2881 ttcttgcggc attttctccg gcaacggaat ttcccgtccg ttttcctgtc cggatacatt
     2941 attcaataag caaagaagac atagtcccag taaaatttgt ctcatacttt atatttcatt
     3001 tttaggttta ctacctatta aatacgaaga tagagaatta tttacctaat tactttcatt
     3061 aagacctgtt ttatttgccc gaacgctact tttattcaaa caaagaacta tatttgcaaa
     3121 aaaaccgact aacaattctg atacttatga aaattttatc tatccatgat ttggcaacaa
     3181 tcaggaagag agcagagcac aatctttcat tgcgcgaaga aagtaatgaa aaggtgactg
     3241 aaaagtgtta cggactggca tccggtgcgc aacatcttca gattctgatc tgcggtggta
     3301 caggctgtaa ggcatcttcc agccagggta ttacagacaa tcttctaaaa gccatccaaa
     3361 agaacgaaat caccgacaaa gtagaagtca tcaccgtagg ctgtttcggc ttctgtgaaa
     3421 aaggtcctat cgtgaaaatt atccccgata atacctttta cacccaagtc actcccgaag
     3481 atgcggaaga aatcatcaac gagcatatca tcggaggacg aagaatcgaa cggttgctgt
     3541 atgtagatcc taaaacggaa cataccgtca gcgactccaa gcacatggat ttctaccgga
     3601 aacaactccg catcgcattg cgtaactgtg gttttatcga tcccgaaaat attgaagagt
     3661 atatcgcccg tgaaggatac tttgcattgg ccgattgcct gcttaacaaa cagccgacgg
     3721 acgttattga tattatcaaa cgttcgggac ttcgcggacg tggcggtggc ggtttcccga
     3781 cgggactgaa atgggaattt gccaacaaac aacagtcgga tgtcaaatac gtggtttgta
     3841 acgccgacga aggagatccc ggtgcattca tggaccgttc cattatggag ggcgacccac
     3901 attcgattgt agaagcgatg tgtgtctgcg gttattccat cgggtccacc aaaggattag
     3961 tatatatccg tgccgaatat ccgttagcta tcaaccgact gaaaacagct atcaatcagg
     4021 cacgcgaata cggattactg ggagatcata tcttaggaac agatttcagt ttcgacatag
     4081 aaatacgata cggagccgga gcttttgtct gcggagaaga aactgccctt attcattcga
     4141 tggaaggaaa acgaggagag ccgactctga aacctccctt ccctgccgaa tccggttatc
     4201 tgggaaaacc aaccaatgta aataatgtgg aaacacttgc caatattccc attattctaa
     4261 ccaaaggagc cgactggttt gcaacgattg gcacagaacg ttccaaagga accaaagtgt
     4321 ttgctcttgc cggaaagatt aataatgtag ggctgatcga agtgccgatg ggaactactc
     4381 ttcgggaagt aatctacgaa atcggaggag gtatcaaagg cggaaagaaa ttcaaagctg
     4441 tacaaacagg aggaccgtca ggcggctgtc tgacagaaaa acatctggac actcccattg
     4501 actttgacaa ccttctctcg gccggttcca tgatgggttc aggagggatg attgtcatgg
     4561 atgaggacga ctgcatggta tccgtagcac gcttttatct ggattttaca gtggaagagt
     4621 cctgcgggaa atgcacacct tgccgcattg gaaacaaacg tctgctggaa ctactgaaca
     4681 agattacgga aggaaaaggc acagaaaaag acctggacac acttgccact ttgggacaag
     4741 tcatcaaaga tacggccctc tgcggactgg gacaaacctc tccgaatcct gttttatcca
     4801 cattggataa cttctacgat gaatatatgg aacacgtgcg ggataagact tgtcgttcca
     4861 agcaatgtaa atcactatta acgtatacca tcagtccgga acgttgcatt ggttgtcatc
     4921 tatgcgccaa aaactgtccg gcggatgcta tcagcgggct ggtgcgcaag ccacatgtca
     4981 ttgctcccga taaatgtatc aagtgcggta tgtgcatggc acgctgcaaa ttcaacgcta
     5041 ttcttgtctg ctaaaatcga ttactatgga agataaacaa atcacactcc agatagacgg
     5101 tcatttcatc accgtccccg aaggaagtac catccttgaa gccgccacga aaatcggcat
     5161 caacataccg accctgtgtc acatcgacct gaaaggcacc tgcataaaga acaatcctgc
     5221 ttcctgtcgc atctgcgtgg tcgaggttat aggacgccgc aatctggctc ctgcctgcgc
     5281 tacccgttgc acggaaggaa tggtagtgaa aaccagtacg ctacgtgtga tgaacgcacg
     5341 caaagtggta gccgaactta tcctgtcgga tcatcccaac gactgtctca cctgccccaa
     5401 atgtggcaat tgcgaacttc agacattagc gctacgcttt aatatccgcg aaatgccttt
     5461 caatggaggc gagctctctc cccgcaagcg ggaaatcact gcctccatcg tgcgcaacat
     5521 ggataaatgt attttctgtc gccgctgcga aagtgtctgc aacgatgttc agacagtcgg
     5581 tgcgctcggt gccatccgtc gcggattcaa cacgacgata gcccctgcct ttgaccggat
     5641 gatgacggaa agcgaatgta cctattgcgg acaatgcgta gctgtctgtc cggtgggtgc
     5701 actgaccgaa cgcgattata cgaaccgtct gctcgacgac ttagccaacc cggataaagt
     5761 ggtgattgtg caaacagccc ctgccgtacg tgctgccctg ggcgaagaat tcggttttcc
     5821 tcccggcaca ctggtaaccg gaaaaatggt ttatgccctg cgtgaactgg gattcgacta
     5881 tgtattcgat actgactttg ccgccgacct caccatcatg gaagaaggat cggaaatact
     5941 aaaccgtctg acgcgctatc tcaacggaga taagtccgta cggttaccta tcctgacctc
     6001 ctgctgtccg gcatgggtga acttcttcga acatcacttc ccggatatgc tggacattcc
     6061 atccaccgcc cgttcaccgc aacagatgtt cggttctatc gccaaatcct attgggcgga
     6121 aaagatggga attcccagag aaaagctggt agttgtatcc atcatgccct gtctggcaaa
     6181 aaagtatgaa tgtgcccgcg atgaatttaa agtgaacggt attcccgacg tagattattc
     6241 tatttccacc cgcgaactgg cacgactgat taaacgcgcc aatatcggct tcccgctggt
     6301 actggacagc ccgtttgaca acccgatggg tgagtcgacc ggtgccggcg ttattttcgg
     6361 tacaacaggt ggtgtaatgg aagctgctct ccgttctgtt tatgaaatct ataccggaga
     6421 atctctgaaa aatgtaaact tcgaacaagt acgcggactt aacggtgtcc ggcgtgctac
     6481 catcaaccta aacggatttg aattaaaagt aggcatcgca cacggactag gcaacgcccg
     6541 ccatctattg gaagatatac ggaacgggca caacgaatat catgtaatcg aaattatggc
     6601 ttgccccgga ggttgcatcg gaggaggcgg acagccattg catcacggca actcggaaat
     6661 attgtatgca cgcgccaacg cactctaccg cgaagacgcc aacaagcctt tgcgcaaatc
     6721 gcacgagaat ccgtacatca agaccttgta cgaggaatat ctcggcaaac cactgggcga
     6781 gatatcggaa acgctattgc acacgcacta tttcaacaaa tctatggatt aactttaaac
     6841 gaagagtaat atgtcagata taaaactagc ctgcgatgtg gcagaacaag tccgaacgat
     6901 ttgcgacaag cacggaaaca acccgggcga actaatcaat attttgcacg aagcgcaaca
     6961 cctgcacggc tacctgcccg aagagatgca acgcatcatc gcttccaaac tcaatatccc
     7021 cgtatcgaaa gtatatggag tggtcacctt ctataccttc ttcaccatga ccccgaaagg
     7081 gaaacatccc atctccgtct gcatgggtac ggcatgttac gtgcgcggct ccgagaagtt
     7141 gctcgaagaa ttcaaacgcg tactaggcat cgaagtcggc gaaaccacac cagatggaaa
     7201 attctcattg gactgcctgc gctgcgtagg tgcctgcgga ctggctccgg tagtgatgat
     7261 tggcgagaaa gtgtacggaa gattgcaacc gatagatgtg aagaagatta tcgaggagtt
     7321 ggagtaaatg tccggaataa aaagcggctg ctttgaaaaa ccaaggcagc cgctttcaaa
     7381 cattttttta acaacaaaca aaaaagcgga gagaacgaga ttcgaactcg tgataccctt
     7441 taggggtata cacgctttcc aggcgtgcct cttcaaccac tcgagcacct ctccttataa
     7501 ttaccaacta gagaacaact ctctataaaa acagaaagca gcaaaaagct gcttcctagc
     7561 ggagagacag ggattcgaac cccgggtacc tcgcggtaca acggttttca agaccgccgc
     7621 aatcgaccac tctgccacct ctccaaaact tccttttcag aagtgctttt cgttaaaagc
     7681 ggtgcaaagg tacgaatata ttttaaacct acaagagttt tcacaaaaaa aatcacgaac
     7741 atcatttcca aagaatagca atatctaggt attttatgtt gaaaagcata aaatagagca
     7801 tatttatgct gattatatga aaaaacgttg taactttgtg cgctctaaag aaaaggataa
     7861 ctacaacctc taattttatc atttatggaa ttaaataaga tctttaaaga cggtctttgg
     7921 agcacagaaa tcaacgtaag agatttcgtt agtcacaaca tcactccgta ttatggagat
     7981 gcttctttcc tcgaaggacc taccgaacgc acaaaagctg tatggaaccg ctgcctcgaa
     8041 gcactggcag aagaaagagc caataacgga gtacgctcac tggataatgt caccgtctca
     8101 accatcactt ctcataaagc cggatatatc gacaaagaaa acgaactgat cgtcggtctg
     8161 caaacagacg aacttctgaa acgtgccatc aaacctttcg gaggtatcaa cgtggtgagc
     8221 aaagcctgcc acgaaaacgg cgtggaagtg gacgaccgtg taaaagatat attcactcac
     8281 taccgcaaga cgcacaatga cggagtattt gacgtatata ccgaagaaat ccgttcgttc
     8341 cgttctctgg gattcctcac cggacttcct gacaactatg cccgcggacg tatcatcggc
     8401 gactaccgcc gtatggctct ctatggtatc gaccgactga ttgaggtaaa aaaagaagat
     8461 ttgcgtaacc ttaccggtcc gatgaccgaa gcccgcatcc gcctgcgcga agaagtggca
     8521 gagcaaatca aggcattgaa ggacatgaag gtaatgggcg aatactacgg actcgacttg
     8581 agccgtcctg cctacaccgc acaagaagca gtacaatggg tgtacatggc ttaccttgct
     8641 gccgtaaaag aacaagacgg tgctgccatg tcactgggta acgtctcttc gttcctcgac
     8701 atttatatgg aatatgaatt gagcaaagga actatcacag aatctttcgc acaggagctg
     8761 atcgaccagt ttgtcatcaa actgcgtatg gtgcgccacc tgcgtatgca atcttacaac
     8821 gacatctttg ccggcgaccc gacatgggtg accgaatcct tgggtggacg cctcaacgac
     8881 ggacgcacaa aggtgacaaa gacttctttc cgcttcctgc aaacactcta caacctcggc
     8941 ccttcaccgg aaccgaacct gactgtattg tggagcccgg aacttccgga aggattcaaa
     9001 gaattctgcg caaaagtatc tatcgacact tcttccatcc aatatgaaaa cgacgacctg
     9061 atgcgtgaag tacgccagtc tgacgactac ggaatcgcgt gctgcgtatc ttatcaggaa
     9121 atcggaaaac aaatccagtt cttcggcgca cgttgcaacc tggctaaagc cctgctgctt
     9181 gccatcaacg gcggacgttg cgaaaacacc ggcacggtaa tggtgaaaaa catccccgta
     9241 ctaaccagcg acacactgaa cttcgaagaa gtaatgagca actacaagaa ggtattgaca
     9301 gaaatcgccc gtgtttacaa cgaagcgatg aacatcatcc attatatgca tgataagtat
     9361 tactacgaaa aagcccaaat ggctcttgta gataccaacc cgcgcatcaa ccttgcttac
     9421 ggtgtagccg gactttctat cgccctcgat tcactgtcgg ccatcaaata tgccaaagta
     9481 accgcacgcc gcaacgacat cggtctgaca gaaggtttcg atattcaagg cgaattccct
     9541 tgcttcggta atgacaacga caaggtagac cacctgggtg ttgacctggt ctatttcttc
     9601 agcgaagaat tgaagaaact tccggtttac aaaaatgccc gtcctactct gtctttgctc
     9661 accatcactt ccaacgtgat gtatggcaag aagacaggtg ctactcccga cggccgcgcc
     9721 aaaggtgtcg cttttgctcc gggagccaac cctatgcacg gacgtgacaa gaacggcgcc
     9781 atcgcctctt tgagttccgt agcgaaatta cgttaccgcg actcacagga cggtatcagc
     9841 aacaccttct ctatcgttcc gaaatcactg ggagctactg aagaagatcg cgtagaaaat
     9901 ctggtgacaa tgatggatgg ttacttcacc aaaggcgctc accacctgaa cgtgaacgta
     9961 ctgaaccgtg aaatgcttta cgatgccatg gaacatccgg aaaaatatcc gcaactcacc
    10021 atccgtgttt ccggttatgc cgtaaacttc gtgaagttga gccgcgaaca tcaattggaa
    10081 gttatcagcc gtagcttcca cgaacgtatg taatcagatc tactcaatat gacgataaac
    10141 gtacattcat acgaaagtat gggaacattc gacgggccgg gcttacggct cgtcgttttt
    10201 cttcaaggat gcaatttccg ctgcctgtat tgtgccaacc ccgacacgat agccggaaaa
    10261 ggaggcacac ctaccccacc ggaagaaatc gtccgcatgg ctatgagcca acgtcctttt
    10321 ttcgggaaac gcggaggagt cactttctcc ggaggagaac ctacgtttca ggccaaagca
    10381 ctagtccctt taatgcgtga actgaaagaa aagggaatac atgtatgcat agacagcaac
    10441 ggcggtatct ggaacgaaga agtagaagaa cttttcaaac tgacggatct tgtattgctg
    10501 gatattaaag agttcaatcc ggcacgccat caggcactga ccggaagaag taacgagcaa
    10561 accatccgca cggcagcatg gctggaagaa aacgagaaac ctttctggct gcgttatgta
    10621 ttagtgcccg gatacagcga tttcgaggaa gacatccgcc gtttaggaga ggctctggga
    10681 aaatataaga tggtgcaacg agtggaaatc ctgccttatc atacattagg cgtacataag
    10741 tatgaagcga tggagcagga atacaagctg aaagacgtaa aagaaaatac ccccgaacaa
    10801 cttgaaaaag ccgcggaggt atttaaagaa tatttcacta ctgtggtggt caattagttg
    10861 aagaagttga gaattgagag ttaactatgc agtataacag tgcgcagcca actctcaact
    10921 ctccattctc aactctcaaa ttcttcaatc acctcaaaac agggacactc tttgatccgt
    10981 tcccaggggt ctacaattcc attataattg gtgtcagggc tcaagtcccg gtgaccgacc
    11041 acctttgcat ccggataacg ctgcaacaac tcgcttacca gacgatgcat cgcctctttc
    11101 tggcgggaag tacgcgtatc tgctgccttt ccgttctcat ccagcccgcc ttcatagcac
    11161 acccctaaac taatcgcatt aaaaccgcgt gcatgagcac ccaccgtatc ttcatccctc
    11221 atcggttcta tctgtcccga cttgcggata taataatgat acccccaaca agaaaagccc
    11281 cgaaagcgat gggcagtgtc cacatccttc gccgtgaagt cgcgatcagc acgggtagca
    11341 gagcagtgaa tcacaatcag actaatcttt ctcatcgtcc ttttcccttt ccgttgtttt
    11401 cacattacac acttccttat gggtagcatt gaagcgcacc tctctcacaa ttctgttccg
    11461 ctttcttttt ccgaagaaag gcacaaggaa catgattaca tccaaaatct tagttacaat
    11521 ttctttcatt tgatctaata ttaaagttat catgctgccg gatccggagc ttctccgctt
    11581 ccaccaccgt ctgaaccgcc accggaacct ttgtcatcgt cttctccttc attgccgcta
    11641 ccgcccgttt gggccaccgc acgcgtcgtt acctgctggt agctaagaat cttcgtgatg
    11701 tccgccaacg tctttccggg acggaaaata atatgggcag ccgtaatcag cgaacttgaa
    11761 aactccttga ccgacacagc tccttcactg ttcaacccga tctgcaaact gcccaaatca
    11821 cccaaccgga ctattcttcc cgctttcaac gcacgcttcg cctcataaag aatacccgaa
    11881 atggcggcac gcacatctgt ctccgtacag gtagaccgac tcgtgattcc ctcgcacaac
    11941 tcttcaaaat ccaactctcc cgaagcctgt gcctgcgcgt aatactttgc cgactcatcc
    12001 tttttggcag gattcttgcg cggcactact gaataagtta ctgtcattgc cataataaaa
    12061 taattttaag atttcacaca tttcgaacgc gttccttatt tgttaacgac ataaagataa
    12121 cacatttttc accctccgga ttccccaacg aagtttcctg atattctatg aataataacg
    12181 acgttattct tttaataaac cattaatttt cagtaacttt atagcataaa ccaaatatca
    12241 ttcaccatgt attatccgga tcagccgttt catatccgca cttataaaaa gtcggaacta
    12301 gctcatcttt acaaccccaa cgtatgtctc aaagtagcct tacaaatact acgtcgttgg
    12361 attgtctaca accttccgct cctgcaagaa ctcgaacaag aaggctatcg tgcccgcaac
    12421 cgccttctct ctccccggca agtggcaacg atcatacgct atttgggaga accctaggaa
    12481 cttaatcaaa aaaacgaaaa gttccattct attattttac aaacaaattt ctttgcaacc
    12541 gcaaattaaa aagaacaaac caacatggag cattttacca tctttcaaga cttttaccgc
    12601 gtcatagccg aaatgacaga agaagaaatc gtatcggcca tcagcaacgg cacataccgg
    12661 gaaacagtgg aggacgtgcg ccgaatcttc gcggaacaag gcgagaaagc agcaaacgaa
    12721 aagaaaatag aactaccgga aatcaccttt tcagccaact accggggagg acgttcaaac
    12781 gcaactctcg tcaagtatct gggatacatc gtggtagaca tcgaccatca gacacaggaa
    12841 gcattggcac gcatcctcgc actggcaaaa aagtgtgccc acacccgcat cgctttcatc
    12901 agtcccaaag gaatgggact gaaaatcgtg gtacgtgtat gccggacgga cgggacattg
    12961 cccgaaacga ttcaggaaat tgaagatttc catcatgccg cttatcacaa aatcgcttcc
    13021 ttttatgccc agctctgcgg agttgaggtc gacacttccg gacaggatgt tagccgcact
    13081 tgcctgttct cttacgatcc ggatatttat ttcaatcccg atgccacagc tgtcatcgtg
    13141 gaacagccac cgatgttctt caagtctcaa aagaagaaaa gggcatccgg caaaaagaaa
    13201 aagacgacag caccagacaa caatcccctc accgaacaag tggcactcaa ctaccattcc
    13261 tcgcacgctt ccttaatggt gactctgaac tattatcaca ataaatccga aaagtacgtc
    13321 accggcaacc ggaacaacta cctgcattgc ctggcttgta tgtacaatcg ctacggcgtc
    13381 ccccaggaag aggcggcagc ttttatcaag agccagttca ccgatcttcc cgcggatgaa
    13441 atggacgcac tgatcgggag tgcttacgga cacaacgagg aattcgacac ccgcaagctg
    13501 aatagtacgc agaagcgaat attacagatt gagcaacata tcaaagaaaa ttacgataca
    13561 cgctacaacg aagtgcttca tatcatggaa tatcgcagaa ggaaaacgga cacggagcaa
    13621 ccggaacctt tccatattct cgacgaaatg atggaaaaca gcatttggat ggagatgaac
    13681 gaactgggct attcgtgcac cgtcaagacg attcagaatc tgatctactc cgacttcagc
    13741 agcacctacc atcctattcg cgagtattta gactcgctgc ctgaatggga cggaacggat
    13801 tatatcggta tccttgccaa cagcgtgcat actagtcacc agaaattttg ggtagaatgt
    13861 ctggaacgtt atctggtggg aatgtgcgct gccgccacac aagatgatgt ggtgaaccac
    13921 actgttttgt tgctttgcag cgaaatacag aacattggaa agactacgtt tatcaacaac
    13981 ctgctgccgc ccgaattgcg cgcctatctt tctaccggtc ttatcaaccc gaacaacaag
    14041 gatgatctgg ccaaaatagc gcaggcgatg cttatcaatc tggatgagtt tgaagggatg
    14101 aacggacggg aactgaatat cttcaaggat ttggttaccc gcaaagtaat cagcatccgc
    14161 ctgccatacg cgcggcgttc acagaacttt cctcacacgg cttcttttgc cggcacatgc
    14221 aattatcagg aagtgcttca cgacaccact ggtaaccgcc gttttctctg ctttcatgtc
    14281 gactcgatgg aatttatcaa aataaactac gcgcagttgt atgcacaaat caagtatcta
    14341 ctcaacaagc cgggatatca gtattggttc acccagtcgg aaaactcacg gattgaagag
    14401 aacaacgagg atttcatttt ccactcaccg gaagaagaac tggtgttgac acatatccgc
    14461 aaaccggaac gtttcgaaaa ggtgcattat ctgacggtca ctgaaattgc ggaattgatt
    14521 cgcgaacgga cggggtatca atattctcac ggaaccaaag cccaactagg aaaagtgatg
    14581 tccaaacacg gcttcgaatt tcataaggga aaaaacggga gaagatacac tgtattcatt
    14641 attgatacgg aacaggtgaa atcaaacagg ctatatgaat aagatttcat ctccttcgca
    14701 cgcaaaaagg tgagggttgg tgagggtact tttgcaactt ttcattttta tatttcttat
    14761 ttctattctt ctattttctt ctaaaaaaaa atacgaatgt tagaaattta ccctcaccta
    14821 ccctcacctt ttcctttttc ttcctcaaaa aaacgaggtt gtgtcaaaac gctgacacag
    14881 cctttttttt atgcgcaaag cccagacttt ctcaagcccg ggctttgtta t
//
