LOCUS       c00377_gnlPro..        20127 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EPPGJGLP_377.
ACCESSION   c00377_gnlPro..
VERSION     c00377_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 03:55:35
            Original ID  :: gnl|Prokka|EPPGJGLP_377
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 6107
            Orig. end    :: 26234
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20127
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[16107:20664]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14557
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..20127
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..20127
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(2907..3803)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg377_8"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 5.3e-13,
                     bitscore: 39.4, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VEYVKLAFRVNGQIIQLPVIEGQKVKKGQLIAAIDPRDIALQYAA
                     TKSAYETASAQVERNKRLLSRQAISVQEYEISLANFQKAKSEYELSANNMRDTKLTAPF
                     DGSIEKRLVENYQRVNSGEGIVQLVNTHNLRIKFTIPDAYLYLLRAKDPRFLVEFDTFK
                     GHVFQAKLEEYLDISTDGTGIPVSITIDDPSFDRDLYAVKPGFTCSIRFTADVGPLVQD
                     SWTIVPLSAVFGESEGNKMYVWVVEDNKVHKREVTVNAPTGEAQALISEGLKPGEKIVI
                     AGVYQLVEGESITTVDR"
     CDS             4735..4950
                     /locus_tag="ctg377_9"
                     /transl_table=11
                     /translation="VLQILYLQPICHRYLQRSNYLSTSALHAFGCRWQMFSCFFNFMVG
                     GLRIKIVLTTVSHKTNSPLCPPCPLW"
     CDS             4974..5189
                     /locus_tag="ctg377_10"
                     /transl_table=11
                     /translation="MLIVYVVSHMVIGTLIIIHYWNFLRSLFIQLSLRITLLFSPIAFF
                     KSRIRSFCLFIAACISFINVFISFCS"
     CDS             5129..5362
                     /locus_tag="ctg377_11"
                     /transl_table=11
                     /translation="LSLHCCLYFVYQRIYFLLQLNFLFFQLNNVGVFLADHCFIYAQLF
                     QRINIFCCNAGFTSAKEFQNTFFVNVRNIVYV"
     CDS             5669..5839
                     /locus_tag="ctg377_12"
                     /transl_table=11
                     /translation="MINNRHPRQTFIYNKSLIDMLIYDYLRGVSVVSSLGVKKLLIFKF
                     ERQYVIYSIKE"
     CDS             complement(6194..6601)
                     /locus_tag="ctg377_13"
                     /transl_table=11
                     /translation="MEITDLKQMTKEEVFNFIRQRLSFSKELQEQFRHVNKDDLAKEHR
                     RFEMSGNESKTGQCTIFNTAILNEFADLGIYDYTSYLFLDFHNGTPTVYLKYFSENENL
                     EYTFTGYTTTEIIFAILELTIFSGKPKRNRS"
     CDS             6795..8009
                     /locus_tag="ctg377_14"
                     /transl_table=11
                     /translation="MINREQYMEQIVPFIDKPFVKVITGIRRSGKSVVLRLIRDELLRR
                     GVREERIIYLNFESFQWIDLKEAKALYAYIRGQAGDAGKYYILLDEIQEVDGWEKVVNS
                     LLVDLDTDIYVTGSNSRMLSSELATYLTGRYVAFHVMTLSFREYLTFHDLQANDPTLNR
                     KEEFQKYLRMGGFPAIHTADYGYEAIYKIVYDIYSSVILRDTVQRHNIRNVELLERVVK
                     FVFDNIGNKLNAKNIADYFKSQQRKVDMNTIYNYLNALESAFIIQRIPRYDIKGKEILQ
                     TNEKYFVSDLSLIYSVMGYRDRLIAGMLENLVCLELKRRGYEVYVGKQDDKEVDFVAIR
                     REEKIYVQVTYQLASQATVEREFAPLLAINDHYPKYVVSMDSLWQDNVEGVRHRHIADF
                     LLDDA"
     CDS             complement(8341..8514)
                     /locus_tag="ctg377_15"
                     /transl_table=11
                     /translation="MMMTYLFYKTDYLYRSFFHKTFFYFTEKHYLCALKMTITLFLTKI
                     VTEYKLKKQILK"
     CDS             8812..9816
                     /locus_tag="ctg377_16"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFEVLDAV
                     MEKLPGFPIVLHGSSSVPEEEVETINKYGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAQ"
     CDS             complement(10001..11161)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg377_17"
                     /sec_met_domain="OAD_beta (E-value: 1.4e-153, bitscore:
                     501.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATVGHVVMILVGLVFIYLAIAK
                     EFEPMLLIPIGFGILIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKNERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFVIATASGVIFVKIFNIFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDSTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(11163..11594)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.7; E-value:
                     2e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg377_18"
                     /sec_met_domain="Biotin_lipoyl (E-value: 8.2e-22, bitscore:
                     67.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKPV
                     AKPVTVRPMPNAPAAPTQVVKPTAPSTGKSGVKSPLPGVILDIKVNVGDTVKKGQTIII
                     LEAMKMENNINADKDGKITAINVNKGDSVLEGNDLVIIE"
     CDS             complement(11619..12539)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg377_19"
                     /sec_met_domain="OAD_gamma (E-value: 1.4e-15, bitscore:
                     48.5, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLVLNEILINNQSNFQD
                     DYGLHSAWIEIFNKSFGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGKKLLDQIVVPAGALGPNQSYARVSDGAAEW
                     EVKSGSGDKYVTPSTNNKTLDSNSKMEKFEEHDADGVGMSISAMSVVFCGLILLFIAFK
                     IVGKVAVNLSKRNAMKSKGIDKHEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRETPPRK"
     CDS             complement(12571..13926)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg377_20"
                     /sec_met_domain="CT_Btheta (E-value: 2.2e-266, bitscore:
                     874.7, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKHYPGDGVVTGCGTIEGRLVYVFAQDFTVSAGSLSETMSLKI
                     CKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQISGIFGPC
                     AGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHSTKSGVTHF
                     TAQTEEEGFELIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPTKPYDMYE
                     VIGAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNASRKGARF
                     VRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTITLRKSYG
                     GSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLAEKEAEYT
                     KLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL"
     CDS             complement(14153..14557)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg377_21"
                     /sec_met_domain="Glyoxalase_4 (E-value: 2.6e-24, bitscore:
                     76.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             complement(14733..15731)
                     /locus_tag="ctg377_22"
                     /transl_table=11
                     /translation="MPLKLTTYYHGKDIPELPGKNAFHSKELFQIYEATPGYTPLLIVA
                     TEDGRPVARLLAAIRKAKKWLPSSLVKHCVVYSEGEFLDESLSTNKEKAEEIFGDMLEH
                     LTQEASRSCVLIEFRNLNNSMFGYRVFRANDYFPVNWLRVRNSLHSMKKTEDRFSPSRI
                     RQIKKGLKNGAKVEEAHTVEEIHDFSRMLHKVYSSRIRRYFPANDFFRHMNDMLIKGQQ
                     AKIFVVKYKEKIIGGSVCIYSEDDAYLWFSGGMRKTYALQYPGVLAVWKALEDARQRGF
                     RHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRVNWNWLNKLLVKFYV"
     CDS             16025..19210
                     /locus_tag="ctg377_23"
                     /transl_table=11
                     /translation="MILGLSLLSAPLSYSVYAEDGVSNTMVQVVTQTKTVKGTIIDESG
                     EPLIGVSIVVKGTSTGTITDFNGNFSIDLPAGRKELVISYIGYKEQTVTVTGNGPVNVK
                     MVSDTQALDEVVVVGYGTMKKRDLTGAITSVKSEDVVMNPSSNPMQALQGKVAGLDITR
                     ESGQAGSGVKMQLRGNRSFQKDSGNPLFIIDGMPGDYSTLNPNDIESIEVLKDASSTAI
                     YGSSGANGVILITTKGGKEGKAIVNFNAYVGVNGWSRTPEMRSGESYIQTLRDASVGAG
                     DGRWSSVADDKNLFTTDAEWSAHQNGQYIDWVDALLKTSVTQNYSVSVAGGTEKTKAYF
                     SLNFSNEDGQFAQDSYKLYSSKIRVDHKIKKWMKVGIDAQLSYVHQNKADSDLQTLMAS
                     NPLGSLYNEDGSINPQPVADPSSTVYNYLLNEDKSLYRNQAQNLKVYFNPYLEITPLKG
                     LTFITRAGASLGYSRSNTFTGEGSVQWYKANQTADGIKAQVKDNRSYNYKWENILTYNF
                     QIKKVHDITLTAVTSWNHNRSDVTTLYQKGVSDNKFLWHNILDGNSATSGSTSYSMSKG
                     MGYVGRLNYSYMGRYLFAASVRHDGSSRLAEGNKWDTFPAFSLGWRISDEKFMESTTNW
                     LSNLKIRFGYGVTGSTAGIDPYSSAASLDATAVNMILGGVLTPIYKFSQNIPNYLLTWE
                     KSYNTNIGIDAAFLNNRIDVSMEYYNTKTKDVIWNKALPVINGAFSPDGGPKANYTTNL
                     NMCETSNKGFELALNTRNIITKNFTWSSSVTFNHNKEKITKLSGGDSDVLNNGDTGYAL
                     ALGEAINSYYHYKLDGVWQKGEETDAAVFGAAPGDLKINIPNLVKESDGRFYKIDEETG
                     SAAVDENGNVIYYTSDNKYTPSDADYQILGHNSPDWSLGFQNNFTWKDFDLSVFVYARY
                     GQMFAYDMLTSYDPKGIRNFPTYFNYWTENNPSNDFPAANANKGLEQYTGYYALRYVDG
                     SFIKIKNITLGYSLPKSILKSAGIEKCRFYATITNPFVFAKSHLLKDYDPEMNGSLKYP
                     LTKQFVFGVNVTF"
     CDS             19305..19463
                     /locus_tag="ctg377_24"
                     /transl_table=11
                     /translation="MSIIQAKKQEMKFLQRSMGLKDYSLIVIHHFTGSYSVSMISCLWL
                     KVVRTAG"
     CDS             19433..20125
                     /locus_tag="ctg377_25"
                     /transl_table=11
                     /translation="VAEGGTDCWITPAGNPDYAKQVIYYDGLATNTNATNKLFGQAYSM
                     IGNCNAVVNRAELLTDGNEKDITTLVAEARCLRAFYYSILVNTYGNVTLTLEESSQDPI
                     LTPQRNSIEELYTQIIDDLKFAANNLEDTPYDNNRARVTKKTALGLLARVYAQGGGEYG
                     LTEEGVSYWQRAKEVAEDMILAYGDCLYDDVEDVWAPANNRNNKEALFIAAGPDATNLE
                     NWNAGTQCN"
ORIGIN
        1 actgacaaca gcatccaacg gctttttgcc cgtctttgcc tccagatcaa tctgttccac
       61 cagtacaatc gcatttttga tattcatccc aatcagtccg agcaaaccaa ggatggagaa
      121 gaagtcgaac gacttgccta gcaacaccaa tcccaaaacg ataccgataa aaataagcgg
      181 taacatcaac aagatcactg tcggcttacg atacgtcctg aacaggaaca acagcgtgac
      241 gaacatcagg aagaacgtca acggtaaatt cttggccaac gcctcgttag actccacctg
      301 actttcctgt tccccgaaat acttcattgt ataccccttc ggcactttaa tctctttctg
      361 caccagcggc caaacctcat tgaaagcagc aatcgcattc actccgcgac gcggatcgca
      421 ttgcgccatc atcaccattt gccggttgta atccttcaca ttcgagaaac gatattggaa
      481 atcaaattcc gataccacct gttccagact ggtcgtctca ttccccgtgc cgaacacggg
      541 caacgtgcgc aggtcgttga tgcggaacga atccaccgtg ttatccttca ataagatagg
      601 aagcacctga tccccctgcc ggtactctcc aagcgtcata cctgtggttc cgatctggat
      661 actttgtgcc attccctgac gcgatacccc taacggttgc gcccgttcgg gactatatac
      721 aggcttccat acaggaactt tatttcccca cgaattgcgc acattgatta aatccggatt
      781 ccggtgcata atctccaaag cctggttggt gagtgccaca agcgtgtcca cattcggacc
      841 gataaacccg atttcgatag cggcatccac cgcaggcgac agtttgaaca gactggtacg
      901 ggtaatcgca ttcggataat tcgccttcat gtacgcgtcg aaatcttctt catactcttt
      961 tgtatattta ctgtccgtca attcaaccaa tacattggca aaattcggtt tcggccccac
     1021 cgaagtagaa gccaggtaat accttaacgg cgtgctaccg aaagtgatcg acactttctt
     1081 cacttccggc tgctttgcca gatgctcttc cacggatttc atctctttca ctacgtcatt
     1141 gatgctatac ccgtcgggat agaacacgtc cgcccggaaa taaggcttat cgagagaagg
     1201 gaagaagttt tgcggcatca ttcccatgat aaccagcgaa gcaacaaaga gcactaccat
     1261 cgaacccagt gtcaatgttt tcctgcgaat cagcgtgcgg aggatggagg cgaatttgtg
     1321 atagaacggt ttgtcatacg ggtctttcgt gccgtccttt gctttcgctt tcaggatgaa
     1381 attaccgaaa acagtggtct gcgtcagcgc gagcacccag ctcaatccca gcgagatggc
     1441 aagcaccaca aaaagcggtt tcacgatttc cgccacggca gaaggagcaa ggtagagcgg
     1501 gaggaacgaa cagatagcga tgaacgtagc cccaagcaat ccccattgcg gaccggttgc
     1561 gccgtctatc agcgctttcc gccggtctac tccgcgggcg atggcaatct gtgcgttgtc
     1621 cgttaccacg atggcgttat ccaccagcat ccccatggcg atgataaatc ccgctaatga
     1681 agtacggttc agcccgacac cgaagaaaga catgataagc aatgtgccgc caatagagaa
     1741 aatcagtgac gagccgatca gcatacctgc gcgcaaaccc atcaccaaca tgataatcac
     1801 aattacaatc agaatcgatt cgatcagatt gatgataaat ccgttgttgg cttcgttggc
     1861 aatttcgttc tccagataca ggctttgcag ttccagtccc acaggcatca gtggcaacaa
     1921 ttcgtccagt ttggctttca cgttcttgcc cgtctgcacc acgtcccgtt gcgggtcggt
     1981 ggagacgccg atgccgatgg cacgtttgcc gttcacgtgc atgatgttgg atggagggtc
     2041 catgtatcct ttttcgatga cggcgatatc gcccagtttc acttgtccgg ctttggtggt
     2101 aatcacctgg ttgcggatat cgtctacggt ggtatacata ccgttggcgg tcacccggag
     2161 ctgttgctcg ccggcacgga tttctccggt attgataatc tggttctgcg attgcaacag
     2221 actggcaagc tgtttcgggt cgatgcccat acctacgagc ttattggtgg aaataaaaat
     2281 attgaccacc tccgtctgcg tcccgaacag ggcgactttc atcaccccgt ccgccgtcac
     2341 tacctgcgtc ttgatccgtt ccgcccagtt gcgcatctct tcgtatgtgt aaccgtcgtc
     2401 cgccgtcaga ccgtaataga taccgaacac gtcgccgaaa tcatcggaaa ccgtcggtgc
     2461 ggaagcaccg cttggcaact gtggctgtat atttagcacc ttccgtcgca actcatccca
     2521 cttctgcgga atggagcttg ccgacaagga aggttgcaac tcgaatgtga tttttgagag
     2581 cccgtacatc gattctgatt ttatcttgta cacaccgctc atactttgaa tctcacgaga
     2641 gataggctcg gtaatcaacc gctccacttc tgccggttcg gcacccggat agcgggtcat
     2701 aataaccgcc gactttatga cgaaaggagc atcctctttc ttacccagct tgccgaagga
     2761 agtgattccc ccaatcagca atacagcaag aaagaaatag atgattttcg tattatctaa
     2821 tgaatatttg gctaaactca taataaatga tcgttgataa ttgatgaatg acagcggata
     2881 aatgatactt aatcatttat caactatcac ctgtcaacag ttgtgataga ttctccttct
     2941 actagttggt atacgcctgc tatgacgatt ttttcaccgg gtttcaaacc ttccgagatg
     3001 agcgcctgtg cttctccggt cggggcgttg acggtcactt cccgtttgtg gactttattg
     3061 tcttctacca cccagacata cattttattc ccttcgcttt caccgaatac ggcactaagc
     3121 ggtacaatcg tccagctatc ctgcaccaac gggcctacat ctgccgtgaa acggatgctg
     3181 cacgtgaaac cgggtttaac agcatacaga tcgcggtcga atgacggatc gtcaatcgtg
     3241 atgctgaccg gaattcctgt gccatccgta gaaatatcaa gatattcttc cagtttcgct
     3301 tgaaacacgt gtcctttaaa tgtgtcgaac tctacaagga aacgcgggtc tttggcgcgc
     3361 aacaaataaa gatacgcatc cggaatggtg aatttgatac gcagattgtg tgtattgaca
     3421 agctgcacga taccctcacc ggagttgaca cgctgatagt tttccaccag tcgtttttcg
     3481 atagaaccgt cgaaaggagc tgtcagcttg gtgtcgcgca tattgttggc agacagttcg
     3541 tattcagact tcgccttctg gaagttggcg aggctgattt catattcctg cacggagatc
     3601 gcttgccggg agaggagccg tttgttacgt tccacttgtg ccgaagccgt ttcgtatgcc
     3661 gatttcgtgg cggcatattg caacgcaatg tctctggggt cgatagccgc gatgagctgt
     3721 ccttttttca ctttctgtcc ttcgatgaca ggaagctgaa tgatttgtcc gttgacccgg
     3781 aaagccagct tcacatattc caccgcttcc acgattcccg agaaatcttt tctgataatc
     3841 gatcttgact cgacaatcgt agtctttacg ggacgtgcag ttgtcgttgt cgtttctttt
     3901 ttctgtccgc agccagccag caagattgca gccgccagga cgaatccaaa ttcctttttc
     3961 atataccacg ttgatgttta gaggttttgc gttgataaat agcgaataat atactaaaac
     4021 aactcctgtt tatttatgtt caatattcct gtcttttcat atcctgcctc ttaaccttta
     4081 tatggaacac aaaaaaacgg gaactttacg agttcaccac agaggacaca gagttcttct
     4141 ctctctttcc gtaagcaaaa cagagcgata aatacgatta ctctgtatta ctctataggg
     4201 aataaaaata gtaaacctcc gtgtcctttg tggtgaaata taaattccca tttagcaaag
     4261 aagtgtgcag aaataaacta aaatcgcact attttgctca tttcagtgca gaaatgaatg
     4321 aaagtttttc ctactataaa gttgaaaaac ataaaaacat ctgccacctg caacgaaacg
     4381 cgtgtaacac actaattaat aaatagttgg aacgttgcag atacctgtgg cagataggtt
     4441 gcagataaag tatctgcaac acgttatata atcaaagaaa aagtcttgat tcctttgtgc
     4501 aaagctatgg gataattggg gtgactctat ggagaatttg tggtgtctct acggggaaac
     4561 gacagtatcc ttacgtggaa actgtagtgt cccgccttag aaactctcgt ttcctaccgt
     4621 ggaaattgta atttctaatg caggaaacga cagttccccg cctggaaacg ggaagttaat
     4681 gtatacaata aacttttgcc ctcctggaga attagcttat gtaaggttta tactgtgttg
     4741 cagatacttt atctgcaacc tatctgccac aggtatctgc aacgctccaa ctatttatca
     4801 actagtgcat tacacgcgtt tggttgcagg tggcagatgt tttcatgttt tttcaacttt
     4861 atggtaggag gattacgcat caaaattgtg cttacaaccg taagtcataa aacaaattca
     4921 cctctgtgcc ctccgtgtcc tctgtggtaa aaaccgtgca ataatgtgtc aatatgctaa
     4981 ttgtttacgt tgtgtcccac atggtaattg gtacgctgat aattattcac tattggaatt
     5041 ttttgcgtag tctttttatc caactgtcgc tacgtataac attattattc tctccaatcg
     5101 cttttttcaa atcccggatc cgttcatttt gtctcttcat tgctgcctgt atttcgttta
     5161 tcaacgtatt tatttccttc tgcagctgaa tttcctcttc tttcaattga ataatgtggg
     5221 cgtatttctc gcagaccatt gttttatcta tgcacagttg ttccagcgta tcaatatatt
     5281 ctgctgtaat gccggcttta cttcggcgaa agagttccag aatacattct tcgtcaacgt
     5341 tcggaacatt gtctatgtat aacataggga attgtcccat ttccacccaa agcaggatcg
     5401 cttctttttc gatgtgatac ttaatcactg ctttttctac actaatccat tttggcatat
     5461 tgcttttgtt ttaatgtgtt ataaaaaaag gagtaaataa cgtattgtcc ggagaggtgc
     5521 aacgaacacc cacgattttt atgatttcgg tcgggtgggg aattggttgg ggtataagga
     5581 ttgttgaaac cgaccggata caataaaagc gtgagtgctg ttgtaccatt atctaaactt
     5641 aaggcttagc aatacccttc accagataat gataaacaac agacacccac gccaaacgtt
     5701 tatatataac aaatctctaa tcgatatgtt gatatacgac tatctacgtg gagtatctgt
     5761 tgtatcatct ctcggtgtga aaaaactgct aatttttaag tttgagagac aatacgttat
     5821 ttactccatt aaggaataaa aaccgctttt gcctgtttca tcacgctgat gggcagaaag
     5881 cgtgtgacaa agatatatgt ttttttcgga ataggatgga aaagaggaaa taaatgcagg
     5941 aaatatggta tgagaataga gagtatggta taaagatggt aaatatgcta tacgggtggc
     6001 aaatataatg tgatgataaa aaggagggag ccaaaagtga aaccatctat tagattgata
     6061 ttatttaggt acggattaca cggatttcgc ggcttttagt ctaatggaac cgtgaaatcc
     6121 gtgtaatccg tgcctaaatg aaagccataa aagtcttttg acctcgcatt gtctttccgt
     6181 gcaattcttt tttttagctg cgatttcttt tgggctttcc ggagaagata gtcagttcaa
     6241 gaattgcaaa gatgatttcc gttgtggtat atccggtaaa tgtatattcc aaattttcat
     6301 tttcggagaa atatttgaga taaacggttg gagtgccatt gtggaagtcg agaaaaaggt
     6361 aagaagtata atcatagatg ccaagatcgg caaactcgtt cagaatcgct gtgttgaaaa
     6421 tcgtgcattg gcctgtcttt gattcatttc cggacatttc gaatctgcga tgttcttttg
     6481 cgagatcgtc tttattcaca tgtctgaatt gttcttgcag ttctttactg aaagaaaggc
     6541 gttgtctgat gaaattaaaa acttcttcct ttgtcatttg ttttaaatcg gttatttcca
     6601 ttttttatta attagtcggg taaaggtact ttctttattt ggtaataaat cggatttagt
     6661 catatttctt ttatttattt ttcggcttat aaccctaaaa gaatctgaat ttatggaatt
     6721 atttagggtt ataaccctaa aaactttccg aaaatagtat atctttgtgc ttataaccct
     6781 aaaaactttt gaatatgatt aatcgtgaac agtatatgga acaaatcgtt ccttttatag
     6841 ataagccgtt tgtaaaagtg ataacgggta ttcgtcgcag tggaaagtcg gtagtgctgc
     6901 gtctgattcg tgacgaactg ttgaggagag gagttcgtga agaacgtatc atctatctga
     6961 attttgaaag ttttcagtgg atagatctga aagaggcgaa ggctttgtat gcttatattc
     7021 gggggcaggc aggagatgcg ggtaaatatt atattctctt ggatgaaatt caggaagtgg
     7081 acggttggga aaaagtggtc aactcacttc tggtagattt ggatacggat atttatgtga
     7141 ccggctccaa ctcacgtatg ttatcgtccg aactggcaac ttatttaacg ggacggtatg
     7201 tcgcttttca tgtcatgacc ttgtctttta gagaatatct gactttccat gacttgcagg
     7261 ccaatgatcc gacactcaac cggaaggagg aatttcagaa atatctccgt atgggaggat
     7321 ttccggccat acatactgcc gattatggat atgaggctat ctataaaatt gtctacgaca
     7381 tctattcttc tgtcattctt cgtgacacgg tgcagcgtca caatatccgg aatgtggaac
     7441 tgctcgaacg ggtagtgaag tttgttttcg ataatatagg caataagctg aacgctaaaa
     7501 atatagctga ttacttcaaa agtcagcaac ggaaggtgga tatgaatacc atctataatt
     7561 atctgaatgc attggaaagt gcttttatca ttcaacgtat tccccggtat gatattaaag
     7621 gaaaggaaat tctgcagacg aatgaaaagt attttgtaag tgacctttct ttgatttatt
     7681 ccgtgatggg ctatcgtgac cggttgattg caggtatgtt ggagaatctg gtctgtctgg
     7741 agttgaaaag aaggggttat gaagtgtatg taggcaaaca ggatgataaa gaagtggatt
     7801 ttgtagccat ccgtcgggaa gaaaagattt atgtgcaagt aacgtatcag ttagcttcac
     7861 aggccactgt tgagagggag tttgctcctt tgctcgccat taacgaccat tatcctaaat
     7921 atgtagttag catggacagc ttgtggcagg ataatgtgga gggtgtcagg catcgtcata
     7981 tagccgattt cttgttggat gatgcttgac gttaaggaat atagaaaacg aaaaagagga
     8041 aattctctgc gagaatctcc tcttttttca tctttcacga aagatcgaat tatttcttct
     8101 tacggtcacc gtaacggctc atgaacttgt caacacgacc tgcagtatct accaatgtag
     8161 atttacctgt atagaacggg tgagaagtgt ttgagatttc aatcttcagc aacggataag
     8221 tttcaccttc gaattcgatg gtttctttag ttgctacagt tgatctagac aaaaacatgt
     8281 caccatttga catatcttta aatactaccg gacggtatga ttctggatga aggccttttt
     8341 tcatttcagt atctgttttt ttaatttata ttctgttact attttggtaa gaaatagtgt
     8401 aatggtcatt ttcagagcgc aaagataatg cttttctgtg aaatagaaaa aggttttatg
     8461 gaaaaaactt cgataaaggt aatctgtttt ataaaataag tatgtcatca tcattggttt
     8521 atacaactat ataaggcaca gactacctat atatcctgca tataacagga tttttctctt
     8581 aattcatata taaatgactg cgtggataca agcaatacgc gttactgtct tttatccgtt
     8641 tatttgcaag gtagacatta caatctaatg tcacactcat attcctgcag aaaaatggtg
     8701 tctgatttaa acctttttct actatatttt tctttccgat gttcgttatt cgatggataa
     8761 tgcttacttt tgcgtagaat ttttattcac taacaataaa ctttaaacaa aatggtaaat
     8821 tacaaagatt taggattggt aaacacaaga gaaatgtttg ctaaggctat caaaggtgga
     8881 tatgctatcc cagcattcaa cttcaacaat atggaacaaa tgcaggctat catcaaggct
     8941 gctgttgaaa ctaaatctcc tgtgattctt caggtttcta aaggtgctcg tcagtatgct
     9001 aacgctactt tgttgcgtta catggcacag ggtgctgtag aatatgctaa agaattaggc
     9061 tgcgcacatc cggaaatcgt tcttcatctt gaccacggag atacattcga aacttgcaaa
     9121 tcttgtatcg attcaggttt ctcttcagtg atgattgacg gttctcatct tccttacgaa
     9181 gaaaacgtag cattgactaa gaaagttgtt gaatacgctc accagtttga cgtaactgta
     9241 gaaggtgaac ttggcgtatt ggctggtgta gaagatgaag tttcttccga ccatcacaca
     9301 tatactgacc ctgaagaagt aatcgacttc gctactcgca ctggttgcga ctctttggct
     9361 atctcaatcg gtacttctca cggtgcttac aaatttactc cggaacaatg ccacatcgac
     9421 ccgaagactg gccgtatggt tcctcctcca ttggctttcg aagtattgga cgctgtaatg
     9481 gaaaaacttc cgggattccc tatcgttctt cacggatcat cttcagttcc ggaagaagaa
     9541 gtggaaacta tcaacaaata tggtggtgca ctgaaagctg ctatcggcat tccggaagaa
     9601 gaattgcgta aagctgctaa gtctgctgtt tgcaaaatca acatcgactc tgactcacgt
     9661 ctggctatga ctgctgctat ccgtaagact ttcgctgaaa aaccggctga attcgaccca
     9721 cgtaagtatc ttggcccggc tcgtgacaac atggaaaaac tgtacaagca caaaatcatc
     9781 aacgtgctcg gttctgacaa caaattggca cagtaataat ctccggatta ttccataaat
     9841 aaaagaaaga ggctgctccg gtttgaacac tggtagcagc cttttttatg acgtttaatc
     9901 gtttcagaac ggagagaaga taacactatg gctgtaataa agaacacccg tgtcacaact
     9961 gaatgtaaca cgggtgttct tatctattat ataatgtttc ttacatcaag aatccaagca
    10021 gaataccggc agcaacagct gaaccgatca ctccggcaac gttcggaccc atagcgtgca
    10081 tcagcaaata gttggtcgaa tcgtattcca aaccaatcac ttgcgagata cgtgcagagt
    10141 cgggaacagc agaaacacct gcattaccga tcaacggatt gatcttatta cccttcttca
    10201 ggaagatatt gaagatctta acgaagatga caccagatgc cgttgcaata acaaatgaca
    10261 atgcaccgag ggcaaagatc ttgatagagt caagcgtcag gaattcggat gcttgtgtag
    10321 aagcacctac tgtcagaccc aacaggatag tgattgtatc aatcaacgga ccactggcag
    10381 tattagccaa acggcgggtt acaccacttt ctttcaacag gttaccgaag aacagcatac
    10441 ccagcaaagg cagaccggaa ggaaccagga aacaagtcag caacaaaccg atgatcggga
    10501 aaatcacctt ctccgtgtga gaaacggcac gcggcggttt catgcggatg acacgttcgt
    10561 tcttggtggt gagcagacgc atgataggcg gctgtatcac cggaaccaac gccatatagg
    10621 agtaggcgga caccgcaatg gctcccatca ggttaggtgc tagcttggaa gaaaggaaga
    10681 tggccgtcgg gccgtctgct ccaccaatga taccgatagc accggcttgc attgggtcga
    10741 aacccatttc caatgcgatc atatatgcac cgaagatacc gaactgtgca gctgcaccaa
    10801 tcagcatcaa ttttggatta gagataagtg ccgagaagtc cgtcatggca ccgataccca
    10861 aaaagatgag tggcggatac cagccggagg tcactccctg atacaatata ttcaatacag
    10921 aaccttcttc ataaataccg actttcagcc cggcatccat attaaaaggt atattaccaa
    10981 tcaatatacc aaaaccgata ggaatcagca gcattggttc gaactctttg gctattgcca
    11041 aatagatgaa taccaagcca acgagaatca tgactacatg ccctaccgta gcattggcaa
    11101 agcctgtgta tgtccagaag tcggccaggt tatttcctaa aaagtttata aagtctccca
    11161 tattattcaa taattacgag gtcattacct tcaagaacag agtctccctt gttgacgttg
    11221 atggcagtaa tcttaccgtc cttatccgca ttgatattgt tttccatctt catggcttcc
    11281 aatatgataa tggtctgtcc tttctttaca gtatcgccta cattcacttt gatgtcgagg
    11341 atcacacccg gcagcggaga ttttactcct gattttccgg tagacggagc ggtcggtttc
    11401 actacttgag taggagcagc aggagcatta ggcatcgggc gtactgtcac gggtttcgca
    11461 acaggcttcg gctgtttctc catttctact ttatagtgtg taccgttcac ttctacatga
    11521 gcgatattat cttcaatatc tccgatggtt actttatatg agttaccgtt gattttatat
    11581 ttatattctt tcatcgtttt aactttttaa aaggtgactt actttctggg aggagtttca
    11641 cgcaaagtgt aaatcttcga actccatggt gagtagctgc gttttacgcg ggtgatggtc
    11701 agcaccgttt cttctacgtc gtgcacctca tcctgcattt cgtgtaatgc catagaaata
    11761 gcagcgtata cttcgcccgg agcctgtgac agttccttag cttcatgctt gtcaatgcct
    11821 ttagatttca tagcgttgcg cttgctcaaa ttaacagcta cttttcctac aatcttaaaa
    11881 gcaataaaga gaagaatcaa tccgcagaat actacgctca tggcagaaat ggacattcca
    11941 acgccatcag catcgtgttc ttcaaacttt tccatcttgg aattgctgtc aagagtcttg
    12001 ttgttggtgc ttggagtcac gtatttgtca ccgcttccac tttttacttc ccattcagct
    12061 gccccgtcgc ttacacgagc gtatgattga ttgggaccga gagcgcctgc gggcactaca
    12121 atctggtcga gcaacttttt gccggagtcg aacagaccaa cccaattagc tgtttccgga
    12181 ttcagcttga agctggtatg gaaagtacca cggttaggtt cgccatctgc ccagaatagt
    12241 gcatgttggc gtggtttcac taaggtaagt atatcacctt tcgggataaa ataagtaact
    12301 gtatcgcccg gttggctgct tactttcagc aagcaagctg ccaggtcggc gctaccgaat
    12361 gatttattga atatttcaat ccatgcgctg tgcaatccgt aatcgtcctg aaaattactc
    12421 tgattgttta tcaggatttc gtttagcacc agcttattgt tcgacttttg ctctccacaa
    12481 gaagtcagac caatcagcaa cagcaaagaa aggaatattc cgattttggt tttgttcata
    12541 atcgttcttg ttttaatgtg aaaagtagga ttacaacgga atattaccat gcttcttagc
    12601 cggattactc aatttcttag tctgcaactg ctgcaaagca cggatcacac ggaaacgtgt
    12661 gttgcgcggt tcaatcacat cgtcgatgta gccatattta gctgcattgt aaggattggc
    12721 gaacaatttc gtgtattctg cttctttttc agcaaggaat tgagcgggat tttcctgatc
    12781 tttggcttcg cgtgcgtaca atacttctac tgctcctgct ccacccatta ctgcgatttc
    12841 ggcagtaggc catgcgtagt tcatgtcacc gcgaagttgc ttacagctca ttacgatgtg
    12901 agaaccaccg taagatttac gcaatgtgat agtaacctta ggcacagtag cttcaccgta
    12961 agcatacaac agtttagcac catgaaggat aacgccattg tattcctgac ctgttcccgg
    13021 aaggaatccc ggtacgtcta ccaacgatac gataggaata ttgaatgcat cgcagaaacg
    13081 aacaaaacgt gcacccttac gagatgcgtt gctgtcgagc acaccagcca gatacttagg
    13141 ctgattagca acgataccta ccgattgtcc gttgaagcgg gcgaaaccga tgatgatatt
    13201 ctttgcataa tctttctgga tttcaaggaa ttcaccgttg tccacaatag cgccgatcac
    13261 ttcgtacatg tcatacggtt tagtagggct gtcggggata atatcgttca aagaatcttc
    13321 cagacggtcg attgggtctg tgcaatctac ataaggagct tcttcaaggt tgttttgagg
    13381 aatatagctc aacagtttgc gaatcagttc gaaaccttct tcttctgttt gggcggtgaa
    13441 atgagtcaca cccgatttag tggagtgaac gcttgcgcca ccgaggtttt cctggctaac
    13501 gtcttcacct gtaacggtct tcaccacttt cggtccggtg aggaacatat aagaagtgcc
    13561 ttccatcatc agtgtgaagt cggtcagagc cggagaataa acagcaccac cggcacaagg
    13621 accgaagata ccggaaatct gcggaataac acctgaagca aggatgttgc gttggaagat
    13681 ttctgcataa cctgccaaag cgttgatacc ttcctggata cgtgcaccac ccgagtcgtt
    13741 gataccgata caaggagcac ccatcttcat ggcctgatcc ataattttac aaatcttcaa
    13801 tgacatcgtt tctgacagtg aaccggcaga aacagtgaag tcctgtgcga acacatatac
    13861 cagacgtcct tcgattgtac cgcagccggt taccacaccg tctcccggat aatgtttttt
    13921 ctccattccg aagttcgtgc atctgtgctc aacgaacatg tccatttctt cgaagctacc
    13981 ctcgtcaagc agcatagcca gacgctcgcg tgctgtgtat ttcccttttt catgttgctt
    14041 cgcaattgct ttttcaccgc ctccgatacg tgctacggca cggcgttcaa taagctcttt
    14101 aattttttca agttgattac tcatgagttc ttgttggttt tagagtttat gattaatgtt
    14161 cgcagagttc tgtcaacacg cccaaagttg atttcgggtg aaggaaagca atattcaaac
    14221 cttcggcacc tttgcgggga gctttgtcga taaggcggat ttctttgctt tctgcttctg
    14281 ccaaagcatt ggctacgcca tcttctacag caaaggcaac gtgatgaaca cctgcacctt
    14341 tgttttcaat gaatttggca atagtactct ccgggcaagt cggctccaac agttcaattt
    14401 tggtttcgcc tacttttaaa aaagcagttc ttactttctg atcttccact gtttcaatgt
    14461 tgtaacactt cagacctaat acattttcgt agtaaggaag ggcttcttcg atgcttttta
    14521 cagcaatgcc cagatgttca atgtgtgaaa tcttcataac tatacttttt ttatttggtt
    14581 ttaatcatgt gcttatatgg cataaaacag cacaaagaaa gacatttctt acctaataaa
    14641 gaaatatttc tgcatttaat tattggatta ttaaacagaa aaaatggtag ggaaggagca
    14701 tgaagagtcg ttttgcaatc ttgagattac atttagacat aaaatttgac taagagtttg
    14761 ttcagccaat tccaattgac acggaaccag cggcgggtac tgctctgctt tcctccgaat
    14821 cggagaacga aatcacgata accgtgtttg cggaacggaa gtcctacatc cataaattcc
    14881 atgtggcgga atccccgttg gcgggcgtct tccaatgcct tccaaacggc cagtactccc
    14941 ggatactgaa gtgcgtatgt ctttctcatt cctccggaaa accaaaggta cgcgtcatct
    15001 tccgagtaga tacagacgga accgccaatg attttctctt tgtattttac tacgaatatt
    15061 tttgcctgtt gtcctttgat tagcatatcg ttcatgtgac ggaaaaagtc gttggcaggg
    15121 aaatatctgc gtatgcggga ggaataaacc ttgtgcagca tccgtgagaa atcgtgtatt
    15181 tcttccacgg tatgtgcctc ctctactttg gctccattct tgagtccttt ttttatctga
    15241 cggatgcgtg acgggctgaa ccggtcttcc gtctttttca tactgtgcag cgaattgcgt
    15301 acccgcagcc aattgacagg gaaataatca ttggcacgga aaacccggta accgaacatc
    15361 gaattattga ggttccggaa ttcgatcagg acacagctac gcgatgcttc ttgtgtgaga
    15421 tgttcgagca tatcgccaaa gatttcttct gccttttctt tgttggtcga aagcgactca
    15481 tccagaaatt ccccttcgct atatactacg caatgtttca ctaaagagga gggaagccac
    15541 tttttcgctt tgcggatggc agcaagcagg cgtgccacag gtctgccgtc ttctgttgct
    15601 actattaata aaggagtata ccccggagtc gcttcataaa tttgaaataa ctctttggaa
    15661 tggaaggcgt tttttccggg caattcagga atgtccttcc catgataata tgtggttagt
    15721 ttaagtggca tctaggtaca aatttacact ttttattctt tattcaacaa caaaacaaag
    15781 aatttgttgg agctgcttga agtaaagtat aatatatagt tgcgtattta atggagaaaa
    15841 tatattttat aggagaaata tggtatgaaa agtgagtacg tattaaaatt agattcgtct
    15901 ttaattaaga ttataatcga atagtttttg caaaacaacg agaattaata ttaactttaa
    15961 attagaacga atgagatgta atgcatttgt tgaagcatgg aagaatcatc atagacgcgc
    16021 ttccatgatt ttagggctgt ctttattgtc tgcccctctg tcatattctg tgtatgcaga
    16081 agatggagtt tctaatacta tggtgcaagt tgtcacacaa acgaaaactg tgaaaggaac
    16141 tatcattgat gaaagcgggg agccgctgat tggagtttct atcgttgtga aaggaacaag
    16201 tacaggtacg attaccgatt ttaacggtaa cttctctatc gatcttccgg cgggaagaaa
    16261 agaactggtc atttcttata tcggttacaa agaacaaacg gtgacagtga caggcaacgg
    16321 accggtcaat gtgaaaatgg tttcggacac acaggcattg gatgaagtgg ttgttgtggg
    16381 ttacggtacg atgaaaaaac gcgatttgac aggagctatc acttctgtaa aaagtgaaga
    16441 tgtagtgatg aatccaagtt caaatccgat gcaggcttta caaggtaagg tggcaggatt
    16501 ggatattacg cgtgaatcgg gacaggccgg ttcgggagta aagatgcagt tgcgtggtaa
    16561 ccggtcattc cagaaggatt ccggaaatcc tttatttata attgatggta tgccggggga
    16621 ttattctaca ttgaatccga atgatattga aagcattgaa gttttaaaag atgcttcttc
    16681 gacagctatt tatggttcaa gtggtgcgaa cggtgttatt ttaattacta ctaaaggtgg
    16741 taaggaaggc aaagcaattg ttaattttaa tgcatacgta ggtgtaaacg gctggtcaag
    16801 gactccggag atgcgtagtg gagaaagtta tatacaaacc ttgagagatg catctgttgg
    16861 tgctggcgat ggacgttgga gttcggttgc tgatgataaa aatctgttta ctactgatgc
    16921 tgaatggagt gcacatcaaa atggccaata tatagattgg gtggatgctt tgttgaaaac
    16981 cagtgtaaca cagaattatt ctgtttctgt ggctggtgga acggaaaaga caaaggcata
    17041 tttttctctg aacttctcta atgaggatgg gcagtttgca caagatagct ataaacttta
    17101 ttcatctaaa atccgggtag atcataagat taaaaagtgg atgaaggtgg gcattgatgc
    17161 tcaactgtct tatgtacatc aaaataaagc tgattctgat ttacagactt tgatggcgtc
    17221 aaatcctctt ggatcgttgt ataatgaaga tggaagcatc aatccgcaac ctgttgccga
    17281 tccttcatct acagtatata attatctttt aaatgaggat aaaagtttgt accgcaatca
    17341 ggctcaaaac cttaaggtct attttaatcc ttacttggaa atcactcctc ttaaagggct
    17401 gacttttatt actcgtgctg gtgctagttt gggatattca cgtagtaaca ctttcacagg
    17461 agaggggtct gttcaatggt ataaggcaaa tcaaacggca gacggcatta aggcgcaagt
    17521 taaggacaac cgttcgtata attataagtg ggaaaatata cttacttaca atttccagat
    17581 taagaaagtg catgatataa ctcttactgc agttacatct tggaatcaca atcgtagcga
    17641 tgtcactact ttgtatcaaa aaggtgtttc tgataataaa ttcttatggc ataatattct
    17701 tgatggtaat tccgcaactt cgggaagtac ttcttatagt atgtctaagg ggatgggata
    17761 tgtcggccgt ttgaactatt catatatggg taggtattta tttgctgcat ctgtccgcca
    17821 tgacggctct tccagactgg cagaaggtaa taaatgggat actttcccgg ctttttcttt
    17881 gggatggaga atctctgatg aaaaatttat ggagagtacg actaactggt tgagtaatct
    17941 gaaaattcgc ttcggatatg gtgttacggg tagtacagcg ggtattgatc cgtattcgtc
    18001 tgctgcatca ttggatgcta ctgctgtaaa tatgatatta ggaggtgttc tgacgccgat
    18061 ttataaattc tcacagaata ttccgaacta tttgcttaca tgggaaaagt cgtataacac
    18121 gaatattggt attgacgctg cattcttaaa taatcgcatt gatgtcagta tggaatatta
    18181 taatacaaaa acaaaagatg ttatatggaa caaggcactt cctgttatta atggagcatt
    18241 ctccccggat ggcggaccta aagcgaatta tactactaat ttaaatatgt gtgagactag
    18301 caataaaggt tttgagttgg ctcttaatac acgtaatatt ataacaaaga actttacctg
    18361 gagttcaagt gtaactttca atcataataa agagaaaata accaaattgt ccggtggaga
    18421 ttcagatgtg cttaataatg gtgacaccgg ttatgcattg gcattgggag aagctattaa
    18481 ctcttattat cattataagt tggatggtgt atggcaaaaa ggtgaggaaa ctgatgcggc
    18541 ggtatttggt gctgcacctg gtgatttgaa aatcaatata cctaatttag taaaagaatc
    18601 tgatggtaga ttctataaaa tagatgaaga aacgggtagt gctgctgtag atgaaaatgg
    18661 taatgttatt tattacactt ctgataataa atatactcca agtgatgcag attatcaaat
    18721 tctgggtcac aactctccgg attggtcttt aggattccag aataatttta cctggaagga
    18781 ttttgattta agtgtgtttg tttatgcacg ttacggacag atgtttgctt atgatatgtt
    18841 gacgtcttat gacccgaagg gtatacgtaa cttcccgacc tattttaatt attggactga
    18901 aaacaaccct tcaaatgatt ttcctgccgc caatgctaat aaaggtctcg aacaatatac
    18961 gggatattac gcattacgct atgtagacgg ttcgtttata aagattaaga acattacatt
    19021 gggatatagt ctgccgaaat ctatcttaaa atcagccggt atagagaagt gtcgtttcta
    19081 tgctaccatt acaaatccgt ttgtatttgc gaaaagccat ttgctgaaag actatgatcc
    19141 cgaaatgaat ggttctctga agtacccatt gaccaaacaa tttgtatttg gtgtaaatgt
    19201 tacattctag tttttcacta aaaaaagtat tgaaatgaaa agtacaatct ataaaatagc
    19261 agcgcttaca ttcgctgtgg cttcaatgtc tgcctgctcg cttgatgagt ataatccaag
    19321 ccaaaaaaca ggagatgaaa ttcttgcaac gttcgatggg cttaaaggat tacagtctta
    19381 ttgttattca tcactttacg ggcagttatt cagtgtctat gatttcttgt ctgtggctga
    19441 aggtggtacg gactgctgga taactcctgc cggtaatccg gattatgcca agcaggtgat
    19501 ttattatgat ggtttagcta cgaatacgaa tgctacaaat aaattattcg gtcaggctta
    19561 ttctatgatc ggtaattgta atgcagtagt aaacagggct gaattactaa cggatggcaa
    19621 tgaaaaagat ataacgacgt tagtggctga agcccgctgt cttcgtgcgt tttattattc
    19681 catattggtg aatacgtatg ggaatgtaac gttaacattg gaagaatcgt ctcaagatcc
    19741 tattttgact ccgcagcgta actctattga agaactatat acgcagataa ttgatgattt
    19801 gaaatttgcg gccaataatc ttgaagatac tccttatgat aataatcgtg cgcgtgtgac
    19861 taagaaaacc gcgttaggac ttttggctcg cgtttatgct caaggtggtg gcgaatatgg
    19921 gctgacagaa gagggagtat cttattggca acgtgctaaa gaagtggcag aggacatgat
    19981 tttagcgtat ggtgactgtc tgtatgatga tgtggaagat gtttgggctc cggcaaataa
    20041 tcgaaataat aaagaagctt tatttattgc tgccggtccg gatgctacga atttggagaa
    20101 ctggaatgct ggaacacaat gtaataa
//
