LOCUS       gnlProkkaPBGEKLAC_5    13528 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PBGEKLAC_5.
ACCESSION   gnlProkkaPBGEKLAC_5
VERSION     gnlProkkaPBGEKLAC_5
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 04:16:38
            Original ID  :: gnl|Prokka|PBGEKLAC_5
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13528
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13528
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[13035:13527]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      13036..13527
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..13528
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13528
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             complement(292..1680)
                     /locus_tag="ctg5_1"
                     /transl_table=11
                     /translation="MTLIKSISGIRGTIGGGAGEGLNPLDIVKFTSAYATLIRKTCKAK
                     SNKIVVGRDARISGEMVKNVVVGTLMGMGWDVVDIDLASTPTTELAVTMEGACGGIILT
                     ASHNPKQWNALKLLNEHGEFLNAAEGNEVLRIAEAEEFDYADVDHLGSYRKDLTYNQKH
                     IDSVLALDLVDVEAIKKADFRVAIDCVNSVGGIILPELLERLGVKHVEKLYCEPTGNFQ
                     HNPEPLEKNLGDIMNLMKGGKADVAFVVDPDVDRLAMICENGVMYGEEYTLVTVADYVL
                     KHTPGNTVSNLSSTRALRDVTRKYGMEYSASAVGEVNVVTKMKATNAIIGGEGNGGVIY
                     PASHYGRDALVGIALFLSHLAHEGKKVSELRATYPPYFIAKNRVDLTPEIDVDAILAKV
                     KEIYKNEEINDIDGVKIDFADKWVHLRKSNTEPIIRVYSEASTMEAAEEIGQKIMDVIN
                     ELAK"
     CDS             complement(1718..2413)
                     /locus_tag="ctg5_2"
                     /transl_table=11
                     /translation="MKKLVFLFLSLLTAGSLFQACDNSKTYAEMLEDEKNAVNKFIKDN
                     DIRVISLEEFERDTVTASKEAGDGYDEYVAFSNGVYMQIVDRGGKEEGENGVEFINEVD
                     TFATDNIICTRYVEKDMMTGEVTCFNVALEEWMDYPDYYKFPLTFRYVQNASTVYGIVL
                     SGSLEYDLLWVNQGYGTAIPSGWLIALPYLRNNAHVRLIVPSKMGHTTAQQYVNPYFYD
                     IWKFEKAKS"
     CDS             complement(2532..3569)
                     /locus_tag="ctg5_3"
                     /transl_table=11
                     /translation="MLTKVIEQAKIDHFSKWFERADKIVIVSHVSPDGDAIGSSLGLYH
                     FLDSQEKTVNVIVPNAFPDFLRWMPGSKDILLYDRYKDFADKLIVEADVICCLDFNALK
                     RIDDMADAVAASPARKIMIDHHLYPEDFCKIVMSYPKISSTSELIFRLICRMGYFSDIT
                     KEGAECIYTGMMTDTGGFTYNSNNREIYFIISELLSKGIDKDDIYRKVYNTYSESRLRL
                     MGYVLSNMTVYPDCNSALITLTKAEQSKFNYIKGDSEGFVNIPLSIKNVCFSCFLREDT
                     EKPMIKISLRSVGTFPCNQLAAEFFNGGGHLNASGGEFFGTMEEAKAVFEKALEKYKPL
                     LTAKS"
     CDS             complement(3616..5763)
                     /locus_tag="ctg5_4"
                     /transl_table=11
                     /translation="MNSFYIHRYPFIRLLIPWIAGIFCGDHFFDRSWAPLCGILFFGFF
                     AALSFALYFLKRYSLRWCFGIAISALCFTGGWLGMTGQLQQAVCSFPKEETVYRVLITD
                     APQPKEHTYLCQALLKERRDTAGIYPIGHTAVLYLQQESSASRLKSGDELLISARISPP
                     LNNRNFDEFDYARFLMRKGISGTGYVVSGKWTLLSSNKPPLSSDELPGSLQQGGMSRLY
                     LNSIASYYRGKMLSFYRELGFADDELAVLSALTIGDKTELSDSVRESYSVAGASHILAL
                     SGLHFGLLYTMLFFILKPIARRGNIGRCVRSVFLLVLLWTFAFFTGLSPSVVRSVSMFS
                     ILAMADMVGREPLSLNTLAVAAWLMLFCNPAWLFDVGFQLSFLAVASILLIQKPIYHLI
                     TVKSRIGKYVWGLMSVSIAAQIGTAPLVLFYFSRFSVHFLLTNLVVIPLITIILYAVVV
                     MLLLTPFSWLQIGVAGGVKKLLEGLNFFVRWVEQLPCASIDGIWLYQSEVLGIYIVIAL
                     LTYYFMNRRYRNLQICLFSILLMGTYHATLYWLDRPQTSLVFYNVRGCPAVHCIKSDGQ
                     SWINYMDTLSNEKRLKHMTANYWKRHHLLPPQEITADCRHAELNRQQQIISYHGCRVCV
                     INDNRWRNKSTVSPLYIQYLYLCKGYDGHLEELAQVFSFSYVILDASLSEYRKHLLESE
                     CKKSGLRFISLSDEGSVHFLL"
     CDS             complement(5772..6422)
                     /locus_tag="ctg5_5"
                     /transl_table=11
                     /translation="MKPIIAPSILSADFGYLAKDIEMVNRSEAEWVHIDIMDGVFVPNI
                     SFGFPVLKYVAKLSKKPLDVHLMIVNPEKFIPEVKALGAHTMNVHYEACPHLHRVIQQI
                     REAGMQPAVTINPATPVALLQDIIRDVYMVLIMSVNPGFGGQKFIEHSVEKVRELRALI
                     ERTGSKALIEVDGGVNLETGARLVEAGADALVAGNAVFGAQDPVEMIRQLHEL"
     CDS             complement(6490..7431)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228:methionyl-tRNA formyltransferase (Score: 216.6;
                     E-value: 6.4e-66)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_6"
                     /transl_table=11
                     /translation="MGTPDFAVEALRQLVEGGYNVVGVITMPDKPAGRGHKIQYSPVKQ
                     YALEQNLPLLQPEKLKDEAFVEALREWKADLQIVVAFRMLPEVVWNMPRLGTFNLHASL
                     LPQYRGAAPINWAVINGDTETGITTFFLKHEIDTGEVIQQVRVPIADTDNVEVVHDKLM
                     MLGGKLVLETVDAILNGTVKPISQEEMAVVGELRPAPKIFKETCRIDWNQPVKKIYDFI
                     RGLSPYPAAWSELIASEKAESVVVKIFESEKVYESHQLAAGTIVTDGKKFMKVAVPDGF
                     VSILSLQLPGKKRLKTDELLRGYRLEDGCKMK"
     CDS             complement(7496..9289)
                     /locus_tag="ctg5_7"
                     /transl_table=11
                     /translation="MKGEKLSLLQRCIKWREANIKEKQFILILSFLVGIFTAFAALILK
                     FFIHQIQNFLTNNFNATEANYLYLVYPVVGIFLAGWFVRNIVKDDISHGVTKILYAISR
                     RQGRIKRHNIWSSTIASAITIGFGGSVGAEAPIVLTGSAIGSNLGSVFKMEHRTLMLLV
                     GCGAAGAIAGIFKAPIAGLVFTLEVLMIDLTMSSLLPLLISAVTAATVSYIVTGTEAMF
                     KFHLDQAFELERIPFVILLGIFCGLISLYFTRAMNSVEGVFGKLNNPYKKLAFGGVMLS
                     VLIFLFPPLYGEGYDTINLLLNGTSAEEWDTVMNNSMFYGYGNLLLVYLMLIILLKVFA
                     SSATNGGGGCGGIFAPSLYLGCIAGFVFSHFSNDFAFSAYLPEKNFALMGMAGVMSGVM
                     HAPLTGVFLIAELTGGYDLFLPLMIVSVSSYLTIIAFEPHSIYSMRLAKKGQLLTHHKD
                     KAVLTLMKMENVVEKDFVVVHPEMDLGELVKAIAASHRNVFPVTDKKTGELLGIVLLDD
                     IRNIMFRQELYHRFTVNKLMISAPAKIFDTDGMEQVMQTFDDTKAWNLPVVDEEGRYQG
                     FVSKSKIFNSYRQVLVHFSED"
     CDS             complement(9290..9898)
                     /locus_tag="ctg5_8"
                     /transl_table=11
                     /translation="MCYFCVLFLTEINQEMIEDIKKACQVMNEGGVILYPTDTVWGIGC
                     DATNEEAVRRVYEIKKRADSKAMLVLVDSPVKVDFYVQDVPDVAWDLIEVADKPLTIIY
                     SGARNLAPNLLAEDGSVGIRVTNEDFSRRLCQQFRKAIVSTSANVSGQPGAANFSEISD
                     EIKSAVDYIVGFRQDDMNKPKPSSIIKLEKGGVIKIIRE"
     CDS             10168..10599
                     /locus_tag="ctg5_9"
                     /transl_table=11
                     /translation="MEEIVFHHTLPIQLRFNDVDKFGHVNNTVYFSFYDLGKTEYFASV
                     CPGVDWEKIGIVVVHIEADFVKQIFASDHIAVQTAVSKIGTKSFHLIQRVIDTETNEVK
                     CICKSVMVTFDLERHESMPLTEEWIEAICKYEERDLQKA"
     CDS             10756..12279
                     /locus_tag="ctg5_10"
                     /transl_table=11
                     /translation="MIADKSINLDTLYKVLFDNEKLELSKECIRKVEESFDFLQSFSSD
                     KIIYGINTGFGPMAQYRIEDQSLIELQYNIIRSHSTGAGKPLPELYVKAAMIARLYTFL
                     QGKSGVHMELVSLLCEFINRGIYPFIPEHGSVGASGDLVQLAHIALTLIGEGEVFYQGK
                     LRDAATVLEENGLQPFSMRIREGLSVTNGTSVMTGIGIVNLIYAKKLLRWSVAASVMMN
                     EIAASYDDFMAQALNEAKHHKGQQEIAAMMREWVAGSKCVLQRENELYNQVHKEKIFEH
                     KVQPYYSLRCVPQILGPIYDELKNAEEVLINEINSACDNPIVDPDTQNIYHGGNFHGDY
                     ISFEMDKLKIAVTKLTMLCERQINYLFHDRINGILPPFVNLGVLGLNYGLQASQFTATS
                     TTAECQTLSNPMYVHSIPNNNDNQDIVSMGTNSALLAKTVIENSYQVMAIQFMGMAQAI
                     DYLKIQDRLSPKSRQVYEEIRSFFPVFTNDTPKYKEIERMMDYLKKENK"
     CDS             12281..13009
                     /NRPS_PKS="Domain: PKS_KR (3-169). E-value: 1.3e-16. Score:
                     52.9. Matches aSDomain: nrpspksdomains_ctg5_11_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     213.3; E-value: 6.4e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_11"
                     /sec_met_domain="adh_short (E-value: 3.3e-36, bitscore:
                     114.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYALVTGGSRGIGRAVSCKLAEMGYFILINYQSNDAEAEKTLQL
                     VQEKGSNGEIMKFDVTDPAAIALALNNWASQHPDEYIEVLINNAGIRKDNLMLWMTGEE
                     WNKVLDISLNGFFYVTQPLLKNMLVKRYGRIVNIVSLSGIQGMPGQANYSAAKGGVIAA
                     TKALAQEVAKKKVTVNAVAPGFIRTDMTEGIDENEWKKHIPAGRFGTAEEVADLVGFLA
                     SPASSYITGEVISINGGLYT"
     aSDomain        12290..12787
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg5_11_PKS_KR.1"
                     /evalue="1.30E-16"
                     /label="ctg5_11_PKS_KR.1"
                     /locus_tag="ctg5_11"
                     /protein_end="169"
                     /protein_start="3"
                     /score="52.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGGSRGIGRAVSCKLAEMGYFILINYQSNDAEAEKTLQLVQE
                     KGSNGEIMKFDVTDPAAIALALNNWASQHPDEYIEVLINNAGIRKDNLMLWMTGEEWNK
                     VLDISLNGFFYVTQPLLKNMLVKRYGRIVNIVSLSGIQGMPGQANYSAAKGGVIAATKA
                     LAQ"
     CDS_motif       12293..12355
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg5_11_0001"
                     /evalue="2.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg5_11"
                     /protein_end="25"
                     /protein_start="4"
                     /score="13.5"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAVSCKLAEMG"
     CDS             13036..13527
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_12"
                     /sec_met_domain="APE_KS1 (E-value: 6.7e-48, bitscore:
                     153.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVVITGMGIYSCIGKNLDEVKDSLYNGKSGIGIDPVRKELGYF
                     SALTGILERPDLKKLLDRRKRLCLPEQGEYAYLATLEAFRNAGIDDAFLEANEVGILYG
                     NDSSAAPVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACA
                     S"
ORIGIN
        1 gctacttgtt gaaaaaatct gcgggacact gttttcttgc aatatcccgc agatgagtac
       61 tttttaaggg acgactaaat aacaaaagag aagtttacta ttagacgaaa ggaagtttag
      121 acttaatcaa aagaaacttt attgttaata ctcaaggaga agagtaacta ttatcattca
      181 gtggatatca tcctaataaa aagtctcgta tatcaatgag acaacttatt cagttatctt
      241 tatgatatac gagactcaaa tgttataaat aaaatcctat tttacaggat attattttgc
      301 taattcatta atcacatcca ttatcttctg accgatttcc tcggcagctt ccatggtaga
      361 agcttcacta tacacacgga tgatcggctc tgtattactc ttgcgcaaat gtacccattt
      421 gtcggcaaag tctattttca caccatcgat atcattgatt tcttcgttct tatagatttc
      481 ctttactttg gcaaggatag catctacatc gatttccgga gtcaggtcta cacggttttt
      541 agcaatgaag taaggaggat aagtagcacg gagctcgcta accttctttc cttcgtgagc
      601 cagatggcta aggaataatg cgatgcctac caatgcatca cgtccgtagt gactggcagg
      661 atagattact ccaccatttc cctcaccgcc gataatggca ttggttgctt tcatcttcgt
      721 tacaacattt acttcgccta cggcagaagc gctgtattcc attccatatt tgcgagttac
      781 atcacgcaaa gcacgggtag agctcaaatt agaaacagtg ttaccggggg tatgtttcag
      841 tacatagtcg gcaacagtaa ccagtgtata ttcttcaccg tacattacgc cattctcgca
      901 aatcattgcc agacggtcaa cgtcagggtc tacaacgaaa gctacatcgg cttttccacc
      961 cttcattaag ttcatgatgt caccgaggtt cttttcaagc ggttcggggt tgtgctggaa
     1021 gtttccggta ggttcacaat agagtttctc tacatgtttc acacctaaac gttcaagaag
     1081 ttcgggaaga atgataccgc ctaccgagtt tacacaatca atagctaccc ggaaatctgc
     1141 ttttttgata gcttctacat ctaccagatc gagagccaat acactgtcga tatgtttctg
     1201 attataagtc aggtctttgc ggtaagagcc caagtgatct acgtcggcat agtcaaattc
     1261 ttctgcttca gcaatacgaa gtacttcgtt gccttcggct gcattcagaa attcaccatg
     1321 ttcattcagc aatttcagtg cattccactg tttcgggtta tgagaagctg tcaggatgat
     1381 accgccacaa gcaccttcca ttgtcacagc aagctctgtg gtcggagtag aagcaagatc
     1441 aatatctact acatcccagc ccattcccat taatgtaccg actactacgt tttttaccat
     1501 ttcacctgag atacgggcat cgcgtcccac aacaatcttg ttgctcttcg ctttgcaggt
     1561 cttacgaatt aaagtagcat aagccgaggt gaattttaca atgtcaagcg ggttcagtcc
     1621 ttctcccgct cctccgccga tggttccgcg gattccagag atagatttga ttagagtcat
     1681 aggtttttaa ctaaaagatt tatctaatgt tagtgcttta gctttttgct ttctcaaatt
     1741 tccagatatc atagaaataa ggattgacat attgttgtgc agttgtatgc cccatcttag
     1801 aaggtacaat caggcgtaca tgtgcattat tacgcaaata aggtaaggca atcaaccatc
     1861 cggatggaat tgcagttcca taaccttgat taacccataa taaatcatat tccaaactac
     1921 cggataaaac gatcccataa acagtagacg cgttttgtac ataacggaat gttaatggaa
     1981 acttataata atcagggtaa tccatccatt cttctaaagc tacattgaaa caagtaacct
     2041 ctcctgtcat catatccttt tctacataac gagtacaaat gatgttatca gtagcaaaag
     2101 tatctacttc attaataaac tcaaccccat tctcaccttc ctctttcccg ccacgatcta
     2161 cgatctgcat atatacgccg ttggaaaaag caacatattc gtcatatcca tccccagctt
     2221 cttttgaagc cgtaacagtg tctcgttcga actcttccag tgaaatgaca cgaatatcat
     2281 tatctttgat gaacttattc accgcatttt tctcgtcttc cagcatttct gcataagtct
     2341 tcgaattgtc gcatgcctgg aacagacttc cggcggttaa caaagagaga aataaaaata
     2401 caagtttctt cattatctgt tatttagcta tattccgcac aaatgtatct caaaatcatt
     2461 aaaagttgaa agggggaagt tgaaagttcg tatcttttaa cctttccata ttcactttta
     2521 accttccatc tttagctttt cgctgttagc aaaggtttat acttctcaag cgctttctca
     2581 aagaccgctt ttgcctcttc catcgttccg aaaaactcac cgcccgaagc gttcaaatgt
     2641 ccgccaccgt tgaaaaattc agcggctaac tgattacatg gaaaggttcc taccgaacga
     2701 agggagattt taatcatcgg cttctctgta tcttcccgca agaagcagga gaaacaaaca
     2761 ttcttgatgg aaagggggat gtttacgaag ccttcgctat caccttttat atagttaaac
     2821 ttactttgct cggcttttgt caatgtgatt aatgccgaat tacaatccgg ataaacagtc
     2881 atgttcgaca atacatagcc catcaaacgc aaacggctct ccgaataggt attgtacacc
     2941 ttacggtaaa tatcatcctt atcgattcct ttggaaagca gctcgctgat gataaaataa
     3001 atttcccggt tatttgaatt ataagtgaat cctcctgtat ctgtcatcat gcctgtgtag
     3061 atacattctg caccttcctt cgtgatatca ctgaaatatc ccatacgaca aatcagccgg
     3121 aatatcaatt cggaagtaga agaaatctta ggataggaca ttacaatctt acagaaatct
     3181 tcgggataca ggtgatgatc gatcatgatt ttacgtgcag gagatgcagc cacagcatct
     3241 gccatatcgt caatacgctt caatgcattg aagtcgagac aacagattac gtcagcttcg
     3301 actatcaact tatcggcaaa atctttgtaa cggtcataca aaagaatatc cttactgccc
     3361 ggcatccatc gcaggaaatc gggaaaggca ttcggcacaa ttacgtttac tgttttttcc
     3421 tgtgaatcca ggaaatgata caatcccaat gatgaaccaa tagcgtcgcc gtcaggagaa
     3481 acatgggata caattactat tttgtcagct cgttcaaacc atttggaaaa atggtctatt
     3541 ttggcttgtt caattacttt cgtcaacata ctcttaaact ttatcaaggt gcaaatgtac
     3601 gataaatctt tgtacttaga gcaaaaagtg gacagaacct tcgtcagaca aagagataaa
     3661 tcgcagaccg gatttcttgc attcgctttc aagtaggtgt ttgcggtatt ccgagaggga
     3721 cgcgtccaat atgacgtaag agaaagaaaa gacttgggcg agttcttcca gatgaccgtc
     3781 atatcctttg cataagtaaa gatactgaat atataacgga gaaacggtag atttgtttcg
     3841 ccaacggtta tcgtttatga cacatacacg acaaccatga taggatataa tctgctgttg
     3901 acggttaagt tcagcgtgcc ggcaatcagc cgttatttct tggggaggaa gaaggtgatg
     3961 acgcttccaa tagttagctg tcatgtgttt cagacgtttt tcattggaga gagtatccat
     4021 atagtttatc caggattgcc cgtcactttt tatgcaatgt actgccggac aaccacgcac
     4081 attgtaaaag actaaactcg tttgaggacg atccagccaa tacagcgttg catgataagt
     4141 ccccatcaac aagatagaaa aaagacagat ttgcagattc cggtatcggc gattcataaa
     4201 ataataggtt agcagagcga tgacaatata gatacctagc acttctgact gataaagcca
     4261 aattccatct atagaagcgc aaggaagctg ctctacccat cggacaaaga aattaagtcc
     4321 ttccaacagc ttcttaacac ctccagccac tcctatctga agccaggaga aaggagtcag
     4381 aagaagcatt acaacaacag catataagat aatcgtaatc aaaggaataa caactagatt
     4441 cgtcaataga aaatgcacgg agaatcgaga gaaataaaac agaacaagcg gagctgttcc
     4501 tatttgtgcg gcaatagaca cgctcatgag tccccaaaca tactttccta ttctactttt
     4561 cacggtaatc aaatggtaga tcggcttttg gataagcaag atagaagcaa cagcaaggaa
     4621 agagagctga aaaccaacat cgaacagcca tgcaggattg cagaataaca tcaaccacgc
     4681 agctactgcc aatgtattta aagataaagg ttcacgacca accatatccg ccatagctaa
     4741 aatcgaaaac atactgaccg aacgtactac cgacggagaa agccctgtaa aaaaagcaaa
     4801 ggtccacaat aagacaagaa gaaaaacaga acgcacacat ctacctatat ttcctcttcg
     4861 ggcaataggt ttcagaatga aaaaaagcat tgtatataaa agcccgaaat gcaaaccgga
     4921 tagagcaaga atatggcttg caccggccac cgaataactt tcacgaaccg aatcacttaa
     4981 ttccgtctta tcacctatgg ttagtgctga aagcacagcc aattcatcgt cagcgaatcc
     5041 gagttcccga tagaacgaga gcatttttcc tctataataa ctagctatac tgttgagata
     5101 aagtctactc atcccaccct gttgcaaaga gccgggtagt tcgtctgaag ataatggtgg
     5161 tttgtttgag gataacaaag tccatttccc ggatacaaca tatcctgttc cgctaatacc
     5221 tttccgcatc aggaagcggg cataatcaaa ttcatcaaag tttcgattgt tgagaggagg
     5281 agaaatgcgg gcagaaatca gcagttcatc tccactcttc aaacgggagg cagacgattc
     5341 ttgctgtaga taaagaaccg cagtatgtcc tatcggatat atgcccgcag tatcacgacg
     5401 ttctttcaat aatgcctgac agaggtaagt atgttcttta ggttgaggcg catccgttat
     5461 caaaacccgg tacactgttt cttctttcgg aaaagagcag acagcctgtt gcaattgtcc
     5521 agtcatccca agccatcctc ccgtaaaaca aagagcggag atagctatcc caaaacacca
     5581 tcgcagcgaa tagcgcttca gaaaataaag agcaaaagac aatgcagcaa aaaagccaaa
     5641 gaagagaata ccacaaaggg gggcccatga acggtcaaaa aaatgatctc cacaaaaaat
     5701 gcctgctatc caggggataa gcaggcgtat aaatggatat cgatggatat aaaaggaatt
     5761 caatagatta gttacagttc gtgcaactga cgaatcattt ctaccggatc ctgtgcacca
     5821 aagacagcat ttccagccac cagcgcatcg gctcccgcct caaccaaacg ggcccctgtt
     5881 tccaggttca cgccaccgtc tacttcaatc agggctttcg aacctgtccg ttcaatcaag
     5941 gcacgcagtt cacgaacttt ttctaccgaa tgttcgataa acttctgccc gccaaatccc
     6001 ggattcacgc tcatgataag caccatatac acgtcccgga taatatcttg cagaagagct
     6061 acaggagtag caggattgat cgttacagca ggctgcatcc cggcttctct gatttgttga
     6121 atcacccgat gcagatgtgg acaagcttca taatgcacat tcatcgtatg agcacccaat
     6181 gcttttactt ccggaatgaa tttctccgga ttcacaatca tcaaatgcac atccaacggc
     6241 ttcttactta acttcgctac atatttcagt accggaaagc caaatgaaat attcggaaca
     6301 aatactccgt ccataatatc aatatgtacc cactccgctt cactgcggtt taccatttca
     6361 atatcctttg ccaaatatcc aaaatcggca gaaagaatag aaggagcgat aatcggtttc
     6421 ataattcttt tattttaggt tctaattgtc tcgtgttcgg gacggttttt attctatctt
     6481 attgtcagat cacttcatct tacacccatc ttccaggcga taaccacgaa gcaactcatc
     6541 tgttttcagt cgtttcttac cgggtaattg taaagaaaga atagatacaa atccatccgg
     6601 tacagctact ttcataaatt tcttgccatc agtcacgatt gttccggcag ccaattgatg
     6661 tgattcataa actttctcac tttcaaatat tttcacgacc acactttctg ctttttcgga
     6721 agcaatcagt tcactccagg cagcggggta aggtgatagt ccacggataa aatcgtagat
     6781 cttcttcacc ggctggttcc agtcaatccg gcaagtttct ttaaatatct tcggagcagg
     6841 acggagttca ccgacaactg ccatttcttc ttgagaaatt ggtttgaccg ttccattcag
     6901 tatagcatct actgtttcaa gaaccagctt tcctcccaac atcatcaatt tatcatgtac
     6961 cacttctaca ttatccgtat ctgcaatagg cacacgtacc tgttgaatga cctctccggt
     7021 atctatctca tgcttcaaaa agaaagtcgt aatcccggtt tccgtatcac cgttgataac
     7081 cgcccagttg ataggagcag ctccacgata ttgaggaagt aaagaagcat gaagattaaa
     7141 tgtacccagt cgcggcatat tccataccac ttccggcaac atacggaaag caactacaat
     7201 ctgcaaatcc gctttccatt cacgcaacgc ttccacaaaa gcttcatctt tcaacttttc
     7261 cggttgaagc aacggtaaat tctgttcgag cgcatattgt ttgacaggag aatattgaat
     7321 cttatgtccg cgtccggcag gtttatcggg catcgtaatc acacccacta cattataacc
     7381 gccttctacc aattgacgca gggcctctac tgcaaaatcg ggagtcccca tatatactat
     7441 tcttaagtcc tctttcttca tcattttaaa tatgttatca ttacttaggc acggattagt
     7501 cttcagaaaa atgtaccagc acttgccgat acgaattaaa tatctttgat ttagagacaa
     7561 atccctgata gcggccttcc tcatctacga ccggaagatt ccaggctttc gtatcgtcaa
     7621 atgtttgcat aacctgctcc attccatccg tatcgaagat tttggcagga gcagatatca
     7681 tcaatttatt aacagtgaaa cgatgataaa gttcttgtcg gaacatgatg ttgcgaatat
     7741 cgtcgagcaa tacaattccc aacaattcac ccgttttctt atctgtcacc ggaaagacat
     7801 ttctatggga agctgcaatt gctttcacca gttcgcccaa gtccatttcc gggtgtacga
     7861 caacgaaatc tttctccacc acgttttcca ttttcatcag cgtcaacaca gctttatcct
     7921 tgtgatgtgt cagcaattgt cccttcttag ccaaacgcat cgaatagata ctatgaggct
     7981 cgaaagcaat aattgtcaga tatgaactta cagatacaat catcaacgga agaaataaat
     8041 catatccacc tgtcagctcg gctatcagga acacccctgt caatggagca tgcatgacac
     8101 cactcattac tcccgccatt cccatcaatg cgaaattctt ctccggcaaa taagcggaga
     8161 aagcaaagtc attgctaaaa tgagagaaaa caaaaccggc aatacatccc aaataaagcg
     8221 aaggagcaaa gataccacca caaccaccgc caccgtttgt tgcactggaa gcaaacactt
     8281 tcaataagat aatcagcatc agataaacca gcaacaaatt gccatagcca taaaacatag
     8341 agttgttcat gaccgtatcc cactcttcgg cagacgttcc attcaacaaa agattaatcg
     8401 tatcatatcc ttcaccataa agaggcggga aaaggaaaat caatacactc aacatcacac
     8461 caccaaacgc cagtttcttg taagggttat tgagtttgcc aaatacacct tctaccgaat
     8521 tcatggcacg tgtgaagtac aacgaaatca gcccacaaaa aattcccagc aagataacga
     8581 aaggaatacg ctccagttcg aatgcctgat cgaggtggaa cttaaacata gcctccgtac
     8641 cagtgactat gtacgaaaca gttgcagctg tcacagcaga aatcagcagg ggaagcaaag
     8701 aagacatggt taagtcaatc atcagcactt ccaaggtaaa taccagtccc gcaatcggag
     8761 ctttaaaaat accggcaatg gcacctgccg caccacaacc tacgagcagc atcaacgtgc
     8821 gatgctccat cttaaacacg ctcccgagat tggaaccgat tgccgaacct gtcagtacaa
     8881 ttggtgcctc tgctccgacc gatccaccaa atccgatggt tatggcactg gcgatagtag
     8941 acgaccagat attgtgtcgc ttgatacgtc cctgcctacg ggagatggca tataaaatct
     9001 tggtgacccc atgactgatg tcatccttta caatattacg cacaaaccaa cctgcaagga
     9061 aaataccgac taccggatat accaaataca ggtagttagc ttctgttgca ttgaaattat
     9121 tagtcaggaa attctgtatc tgatggataa agaatttcaa tattaacgca gcaaacgcag
     9181 tgaagattcc gaccaggaaa cttaatatca ggataaattg cttctccttt atgttcgctt
     9241 cccgccattt gatacaacgc tgcaataaac taagtttttc tcctttcatt tattcgcgaa
     9301 ttatctttat cactccacct ttttccaact taataatact tgagggtttc ggcttattca
     9361 tatcatcctg acgaaagcca actatataat ctaccgccga tttgatttca tcactgattt
     9421 cactaaaatt agcagcaccc ggctgcccgc tgacattagc cgaagtagaa acaattgctt
     9481 tacggaactg ctgacagagt cttctggaaa aatcttcatt cgtcacacga atccctacac
     9541 tgccatcttc ggccagcaga ttaggtgcta aatttcgtgc tccggaataa ataatcgtca
     9601 acggcttgtc ggcaacttca atcaaatccc atgctacatc aggtacatcc tgtacataaa
     9661 aatccacttt aaccggagaa tccaccaaca ccaacatagc tttgctatca gcacgtttct
     9721 tgatctcata tacccggcgt acagcctctt cattagtcgc gtcacagcct ataccccata
     9781 cggtatcagt gggataaagg atcactcctc cttcattcat cacctgacag gcttttttaa
     9841 tatcttctat catttcttga ttaatttccg ttaagaacaa gacgcaaaaa taacacattt
     9901 attccattta gtgaaatcta tcctgacgtt tttaaattac cctttaaaat caactgttgg
     9961 cagacaataa tttaactatt acattattac aagcgtgttt ccctaacagg acaaacatcc
    10021 caaaacttcg ttttaaacga ttattaacga aaatcttcct tatctccgaa agcagaatca
    10081 ttagaaatct ctatctttgc ctcaatttca agcaagaaag caaaagtgcc atttttgtgt
    10141 cgaatttaaa acgtttaaga gaaaacaatg gaagaaatcg tatttcatca cacattacct
    10201 atccaattgc gattcaatga tgtagacaaa tttggtcacg tcaacaacac agtttacttc
    10261 tccttttacg acttaggaaa gactgaatac ttcgcttcag tatgccccgg agtagattgg
    10321 gaaaagatcg ggattgtcgt tgtccatatc gaagcggatt tcgtcaaaca gatattcgca
    10381 tccgatcata tcgccgtaca gactgctgtt tctaagatag gcaccaaaag ctttcacctg
    10441 atccagcggg ttatcgacac agaaacgaat gaagtaaaat gtatctgcaa gtctgttatg
    10501 gttactttcg atcttgaaag acatgaatcc atgccactga cagaagaatg gatagaggcg
    10561 atctgcaaat atgaagaacg ggacttgcaa aaagcataga tagatttttt gaaaaagccc
    10621 cctcacgaat gagaaacaaa acaagcaaaa ccaattctcc ggaaaaagtt ttattctaat
    10681 tcatgtccgc tatataacag aaattgccta tttttgtacc ttaattaata aggcataaaa
    10741 tatctagtac agaaaatgat agctgacaaa agtataaatt tagataccct ttataaagta
    10801 ttgtttgata atgagaagct ggaactctct aaagaatgca tccgaaaagt agaggaaagc
    10861 ttcgatttcc tacaatcttt ttccagcgat aagattattt atggtatcaa tacggggttc
    10921 ggcccaatgg cacaataccg gatagaagat cagtcactga tcgaacttca gtacaatatc
    10981 attcgaagcc attccaccgg tgccggtaaa ccacttcccg aactttatgt aaaagcagct
    11041 atgattgccc gcctgtacac ttttctacag gggaaatcag gagtacacat ggagctggta
    11101 tctcttctct gtgaatttat caaccgtgga atttatccgt tcatacccga acatggaagt
    11161 gtaggtgcca gcggcgatct cgtgcaactg gcccatattg ccctgacatt aataggagaa
    11221 ggggaagttt tttatcaggg gaaattgcgt gatgccgcta ctgtgcttga ggaaaacggt
    11281 ctgcaacctt tttcaatgcg catccgcgaa ggattatccg tcacaaacgg tacttctgtg
    11341 atgacaggaa tcggtatcgt caatctgatt tatgccaaaa agctgctccg ttggtcggta
    11401 gccgcttctg tcatgatgaa tgagattgcc gcctcttatg atgatttcat ggcacaggca
    11461 ttaaacgagg ccaagcatca caaagggcaa caagagatag ccgctatgat gagagaatgg
    11521 gtcgcgggca gcaaatgcgt acttcaaaga gagaatgagc tatacaacca ggtgcacaaa
    11581 gaaaaaatct tcgagcacaa agtacagccc tattattcct tgcgatgtgt tccgcaaatc
    11641 ctcggtccca tctatgatga gctgaaaaat gcggaagaag tattgattaa cgaaataaat
    11701 tccgcctgcg acaatccgat tgtcgatccg gacacacaaa atatttatca tggcggtaac
    11761 ttccacggag attacatctc tttcgaaatg gataaactga aaatcgccgt aaccaaactg
    11821 accatgcttt gcgaaagaca gatcaattat ctgttccacg accgtatcaa tggcatcctg
    11881 cctccttttg taaacttggg agtgcttgga ttgaactacg gtttgcaggc ttcgcaattc
    11941 acagcaacat ccactacagc cgaatgtcag acattgtcga atccgatgta tgtgcacagt
    12001 attcctaaca acaacgataa tcaggatatt gtcagcatgg gaaccaactc ggctctatta
    12061 gcaaaaacag tcatagagaa ttcttatcag gtaatggcta ttcaatttat gggaatggcg
    12121 caagccatcg actacctgaa aatacaggat cgtctaagtc ccaaaagccg tcaggtgtat
    12181 gaagaaatac gtagtttctt ccctgtattt accaatgaca cacctaaata taaagagata
    12241 gaaagaatga tggactatct caaaaaagaa aataaataaa atgaaatacg cattagtaac
    12301 cggaggaagt cgaggtatcg gccgtgctgt cagttgcaaa ctggcggaaa tgggctactt
    12361 tatactgatt aattatcaga gtaacgacgc agaagcggaa aaaacgttgc agttagtgca
    12421 ggaaaaagga agtaacggag aaatcatgaa gttcgatgtg acagaccctg ccgctattgc
    12481 ccttgccttg aacaactggg cgtcacaaca tcctgacgaa tacatcgaag tactgattaa
    12541 caatgcgggc atccgcaaag acaacctgat gctttggatg acaggagaag aatggaacaa
    12601 agtgctcgat atcagtctga acggattctt ttatgtgaca caacctttat tgaagaatat
    12661 gctggtcaaa cgttatggac gtattgtcaa tatcgtatcc ttgtcaggta ttcagggaat
    12721 gcccggacaa gccaattatt ccgcagccaa aggtggcgta atagctgcta ccaaagcact
    12781 ggcacaagaa gtggccaaga aaaaggtaac agtcaacgca gttgctcctg gatttatccg
    12841 cacggatatg acggaaggga ttgatgagaa cgaatggaaa aaacacattc ctgcaggacg
    12901 tttcggtact gcggaagagg ttgccgatct cgtcggtttt ctggcatctc cggcctcatc
    12961 ctatatcaca ggagaggtga tttccatcaa cggaggacta tatacttaaa acaaaagcat
    13021 agaatagaca aaataatgaa aagagttgtt atcacgggaa tgggaattta ctcttgcatc
    13081 ggcaagaacc tggatgaagt aaaagactca ctatacaatg ggaaatcggg gattggcata
    13141 gatccggtac ggaaagaact gggctatttt tctgcattaa cgggcatatt ggaacgtccc
    13201 gacttgaaga aactattaga tcgtcgtaaa cgtctctgcc tgccggaaca gggagagtat
    13261 gcttatctcg ctactttgga ggctttccgc aacgccggta ttgacgatgc ttttctcgaa
    13321 gctaatgaag tgggtatctt gtatggcaat gatagtagtg ctgcccctgt catcaacgca
    13381 gtggacatca ttcgtgaaaa gaaaaacaca gcgttggtag gttccggttc tattttccag
    13441 tcgatgaatt ctaccgtgac aatgaacctg tcggttatct tcaagcttag aggagttaac
    13501 ttcaccattg ccggagcttg tgcaagtg
//
