LOCUS       c00044_gnlPro..        16493 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PBGEKLAC_44.
ACCESSION   c00044_gnlPro..
VERSION     c00044_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 23:33:42
            Original ID  :: gnl|Prokka|PBGEKLAC_44
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16493
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16493
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2944:6493](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(2945..6493)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16493
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16493
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             2..1084
                     /locus_tag="ctg44_1"
                     /transl_table=11
                     /translation="SINEGEFFVIMGLSGSGKSTLLRCINRLIRPTTGQVLVNGVDISK
                     ISEKELLQVRRKELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVG
                     LKGYENQMVGELSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQS
                     KMKKTIVFITHDLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRS
                     KIITASSLMIDKPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKL
                     RSRQEKSIETIVRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETHEFLGTIPLSSLII
                     EVTGKDKEEINEIIQNAIDL"
     CDS             1081..1905
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.5; E-value: 8.7e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg44_2"
                     /sec_met_domain="BPD_transp_1 (E-value: 4.8e-29, bitscore:
                     92.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETVINWMMVHFSTFFDAINAGIGSFIIGFQHVLFGIP
                     FYITILVLAALAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSPRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             1926..2792
                     /locus_tag="ctg44_3"
                     /transl_table=11
                     /translation="MRIYKIVGIVLSAILLLASCTNSDLEKKKVKIAYANWLEGIAMSH
                     LAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEFLG
                     EVYGEARVGLVVPQYVTIQSISELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGLDG
                     YTLMTSSSSTMLASLKKAMDKGEWIVITGWTPHWMFDQFDLKFLDDPKKVYGDLEEIHA
                     IAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRQLVDSW
                     IPKSENK"
     CDS             complement(2945..6493)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_4"
                     /sec_met_domain="PFOR_II (E-value: 1.9e-18, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 2.2e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.9e-31, bitscore: 100.6,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.2e-12, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 7.8e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.4e-07, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.7e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 4.7e-25, bitscore: 78.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDYLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDNPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     EQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTAKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAQAENWTYCAENVKTKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIAADGTPAEVKELFAEWINNMLDADKTKE
                     LAAKIIPVVEANKDKCNHCKQIAELQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPTEAEELFKAAEENAKW
                     RYNSYKRLARENWGAE"
     CDS             complement(6526..7704)
                     /locus_tag="ctg44_5"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGNDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLIDQVFKHPEWS
                     KELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFANSLWKDHKVHKGD
                     KNVSFMVDEVMPFKICQEGAKIKNNPNVTYALHKAEIGRGNQIPLWMFGFLY"
     CDS             7852..9069
                     /locus_tag="ctg44_6"
                     /transl_table=11
                     /translation="LNSFEMTKKALYIFNPEHDLALASGETNYMAPASARRMASELALL
                     PMWYAEEGSAVLASSAYNLDYLKQMQELLGVSIHLMTEPELAVGPDLDIRPWGWDVALR
                     KRLSGLGVDEALLPSMEQLNGLREYSHRSKAVSLLPELQLNEYFCGESYYLKTQEEWKT
                     FVEERECCLLKAPLSGSGKGLNWCKGIFTPFISGWCTRVAASQGGIIAEPIYNKVEDFA
                     MEFYSDGTGEVTFMGYSLFHTGKSGMYEGNRLLSNEAIWKQLSQYVPSKVLTDLENCLK
                     YRLSALVGTVYKGYLGVDMMICRFPENEKPVFRIHPCVEINLRMNMGVVARFLYDRYVR
                     SGSTGRFVIDYHPSEGEALQEHERMSATYPLEIREGRVYSGYLPLVPVHRRSCYRAWIW
                     VTPDNI"
     CDS             complement(9080..10636)
                     /locus_tag="ctg44_7"
                     /transl_table=11
                     /translation="MNDLLRKLPIGIQTFEKLRKGDYLYVDKTELVWKIAYTSTPYFLS
                     RPRRFGKSLLLSTFEAYFEGKKELFEGLAIEKLETKWEKHPVLHLDLNAEKYDSPERLY
                     DILSRQLTLWEIQYGKGIDENTLSGRFSGVIRRAYEQTGSSVVVLVDEYDKPLLQALGN
                     DVLLDEYRKTLKAFYGVLKSADRYLRFVFLTGVTKFSQVSVFSDLNQLQDITLWPDYGT
                     LCGITLQELLDTFQPEIKILAANNSISYDDAVQRMTRLYDGYHFCINSVGIFNPFSVLN
                     VLKSKVFDNYWFQTGTPTFLVEMLQETEYDLRTLLDGIEAPSSMFSEYRVDSNNPIPLI
                     YQSGYLTIKDFDREFGNYLLQFPNDEVRYGFINFLVPFYTGVRNSDQGFYIGKFVQELR
                     SGDYDAFLTRLQAFFADFTYELNEQTERHYQVVFYIVFKLMGQFTDAEVRSARGRADAV
                     VKTPKYIYVFEFKLHDTAEAALKQIDDKGYLIPYQADGREVIKIGVEFSAEKRNISRWL
                     V"
     CDS             complement(11245..12453)
                     /locus_tag="ctg44_8"
                     /transl_table=11
                     /translation="MKKIFRKIHLWLSVPFGLIITLVCFSGAMLVFENEVNEWFRRDLY
                     YVETVKESPLPMDKLLEKVATTLPDSVSVTGVSISSDPGRAYQVSLSKPRRASLYVDQY
                     TGEVKGKSERSGFFMFMFRMHRWLLDSMNPGNEGIFWGKMIVGVSTLLLVFVLISGIVI
                     WWPRTRKALKNSLKITATKGWRRFWYDLHVAGGMYALIFLLAMALTGLTWSFPWYRTAF
                     YKVFGVEVQQRVAQGHEQKSDAQKRDTKLAAHREKKREGNEVRKGERSGRPENNHSDMY
                     SVTSPFVYWQEIYDKLRRQNPEYKQISISSGTASVSFNRFGNQRASDRYSFNTDNGEFT
                     ETSLYQHQDKSGKIRGWIYSVHVGNWGGMFTRILTFIAALLGAALPLTGYYLWIKRLIK
                     VLK"
     CDS             complement(12543..13931)
                     /locus_tag="ctg44_9"
                     /transl_table=11
                     /translation="MKKFLLQAFAVAFCLSSGVFVASCDDDNNPVDNPPIDGETAYVVA
                     ATTGEASYLVVANSLDEGTVSTQGNGTEVIGGTYWVYKGLDYVFALVYNKGGAGTGASY
                     YLGADGKMKEKYTYTYNRITSYGTWGDKVVTVSTGDSKITDEDQNVAQALLFNYLDATD
                     GSQEEGTLLAENYLGNGEKVSWAGLVEANNKIYTSVIPMGMSKYGIKKWPEAVTDQELV
                     TKTDGGSGSGAYTAGVIPSTQYPDNAYVAIYNGTNFNETPVIAKTDKIGYACGRMRSQY
                     YQTIWAADNGDVYVFSPGYGRTAVSSSDLKKVTGQKPSGAMRIKAGATDFDPDYYVNFE
                     EIGTKHPIFRCWHISEDYFLLQLYKKGAEDMINGGTSADVSELAVFKAEDQTIMPVTGL
                     PADGKFGGEPYGEKGYAYMAVTVTTGEKPAFYKIDAKTGKAVKGLTVEADAITTVGKME
                     YLSK"
     CDS             complement(13972..16386)
                     /locus_tag="ctg44_10"
                     /transl_table=11
                     /translation="MSNKYFLVFLAFLFSVSVYSQHGRHRNSLISGRVMSTEKEVVDFA
                     TVYLKGTNQGCYTDEKGIYHLKTTAGEYTLVVSAIGYQTVEKKVKLAKGERIKVNVTIA
                     PAVKELGEVLVTTSGVGRVNQSAFNAVAIDAKKLHNSTQTLAGALTKVPGVKLRESGGV
                     GSDMQLYIDGFSGKHVKIFIDGIPQEGAGAAFDLNNVPINFADRIEVYKGVVPVGFGTD
                     AIGGVVNIVTNKQPGKWFMDASYSYGSFNTHKSYVRFGQTFKNGFMYEVNAFQNFSDND
                     YYVDTYVREFEIKEDGSVRFPPLDKNKIYHLKRFNDQYHNEAVIGKIGLVGKKWADRLA
                     LSFNYSHFYKEIQTGVYQDVVFGEKFRKGHSLVPSLEYYKKNLLVKNLDLLLTANYNHN
                     ITNNVDTASRAYNWRGDFYEKGSRGEQSYQNSESKNRNWNGTLKMNYHIGQAHTLTFSP
                     VISDFERTSRSTIGASSKFTDFSIPKITRKNVSGLSYRLMPSDRWNVSAFAKYYRQYNK
                     GPVSQNTDGIGNYINLSNTASALGYGAAGTYFIWKDLQVKLSYEKAFRLPTTDELFGDE
                     DLEAGKMNLKPEKSDNVNLSFSYNHQFGKHGLYAEAGLIYRDTKDYIKRGLDVLGGTSY
                     GYYENHGHVRTKGYNLSLLYSFSRWFDIGGTFNSIDTRDYEKFLAGSSLQESMHYKVRM
                     PNLPYRYANINANFYWNDLFVKGNVLSIGYDSYWQHDFPLYWENLGDKDSKNMVPEQFS
                     HNLSLSYTMKNGRYNVSFECRNFTDAQLFDNFSLQKAGRAFYGKFRVFFGK"
ORIGIN
        1 ttcaattaat gaaggagagt ttttcgtgat aatgggactc tcgggaagtg gaaaatcgac
       61 attactgcgt tgtatcaatc gtctgatacg tcctactacc gggcaagtgc ttgtaaacgg
      121 agtagatata tctaaaattt ccgaaaaaga attattgcag gttcgtcgga aagagctggc
      181 gatggttttc cagaatttcg gtctgttacc tcaccgttcc gtattgagca atatcgcgtt
      241 cggcctcgaa cttcagggag tgaagaaaga ggaacgtgag aagaaagcga tggaaagcat
      301 gaagcttgtc ggattgaaag gatatgaaaa tcagatggtg ggcgagcttt ccggtggaat
      361 gcaacagcgt gtcggactgg cccgcgctct ggctaataat cccgaagtac ttctaatgga
      421 tgaggctttc tctgcgctcg atcctctgat tcgtgtgcaa atgcaggatg aactgctggc
      481 tttgcagtcg aagatgaaaa aaacaattgt ctttattacc catgacttga gtgaagcgat
      541 taaactgggc gaccgtattg ctattatgaa agacggagag gtggtgcagg taggtacttc
      601 agaagaaata ctgaccgaac cggctaacga ttatgtagcc cgttttgttg aaaacgtgga
      661 caggagtaaa attattaccg cttcttcttt aatgattgac aaaccactgg tggcccgtct
      721 gaagaaagag ggacctgaag tattgattcg taagatgcgt gcgaagaata tcaccgtatt
      781 acctgtcata gacgccgatg ataaactggt cggagaagta cgtctgaacg acctgcttaa
      841 gttacgtagc agacaggaaa aatccattga aacgattgtg cgtaccgaag tacattctgt
      901 attggaggat acagtgttgg aggatatact tcctttaatg acaaagagca attcgccggt
      961 atgggtgatt gatgagacgc atgagttttt aggaacaatc ccgctttcct ccttaatcat
     1021 cgaagtgacg gggaaagata aagaagaaat aaacgaaata attcaaaacg caatagattt
     1081 atgataaata taggacaata tatagagacg gtcatcaatt ggatgatggt acatttttcc
     1141 actttctttg atgccataaa tgcaggcatc ggtagtttta ttataggatt ccaacacgta
     1201 ctttttggaa taccttttta tataaccatt ctagtgcttg ctgcactcgc atggatgaag
     1261 gcaggacgtg gtacggcaat tttcaccgca ttgggattat tactgattta tggaatggga
     1321 ttttgggagg ctactatgca aaccctggct cttgtttttt catctacctg tctggccctg
     1381 attgttggtg tacctttagg agtgtggacg gcaaacagtc cgcgtgcaga gaaaatactt
     1441 cgtcctgttc tcgacttaat gcagacgatg cctgcttttg tttatctgat tcctgccgtt
     1501 ttgtttttcg gattgggagc agtgccggga gtgtttgcca ccattatctt tgctatgcct
     1561 cctgtggtcc gccttactgg attgggaatt cggcaagttc ctaaaaatgt agtggaagct
     1621 tcccgttcgt tcggggctac ccgttggcag ttattgtata aagtgcagct tcctttggcg
     1681 ttgccaacca tcctgacagg tgtcaatcag acaataatga tgtcgctttc tatggttgtc
     1741 attgctgcca tgattgctgc cggtggtctg ggagaaattg tattgaaagg tattacccaa
     1801 atgaaaatcg gacttgggtt tgaaggtggt atcgcagttg ttattttagc tatcatctta
     1861 gaccgtatca cacaaggaat ggcaggacga aaaaacaaga actaaacgga aaggataaaa
     1921 tacgtatgag aatatataaa atagtaggaa tagtattgtc agctatactt ttgctggctt
     1981 cctgtactaa ttcagactta gagaaaaaga aagtaaaaat agcctatgcc aattggttgg
     2041 aaggtattgc catgagccat ttggctaagg tggtattgga agaacatgga tatgaggttg
     2101 aattgcaaaa tgctgatctt gcccctattt ttgtatctat gtcaggaaag aaatcagatg
     2161 tgtttctgga tgcctggtta ccaataacga tgaaagatta tatggatcag tatggagaca
     2221 gcatcgaatt tctgggtgag gtatatggag aagcccgtgt agggctggtt gttcctcaat
     2281 atgttacgat tcagtctatt agtgagctgg aagctaataa agaccgtttc tcttccgaaa
     2341 tagtgggaat tgatgccgga gcagggataa tgaagacgac cgataaggcc attgctgctt
     2401 atggacttga tgggtatacc ctcatgactt caagtagttc caccatgctg gcttctttga
     2461 aaaaagcgat ggacaaagga gaatggattg tcatcacggg gtggacaccg cattggatgt
     2521 tcgaccagtt tgacttgaaa ttcttggatg atccgaagaa agtatatgga gacttggaag
     2581 aaatacatgc tattgcatgg aaaggattca gtgagaaaga tccgtttgct gccgaattct
     2641 ttggcaacat taaactaacg acagaagaac ttagctcttt tatgacagct atgaaggatg
     2701 cccggatgga tgaagaagaa atagcccgca aatggaggga tgaacatcgg cagttggtgg
     2761 atagttggat tccgaagtct gagaataaat agattggagc attgttattc ttaattttaa
     2821 atataaaata gacatgaact ctagtgggaa aaagggagta ttgtttatgt tagacagagt
     2881 tcatacaata aaaaaacggt aatcttctac aagattaccg ttttatattt atagggtatt
     2941 actattattc agcaccccag ttttctctag ccaaacgttt gtagctgttg taacgccatt
     3001 tagcgttttc ttcagcagct ttgaacagtt cttcagcttc agtaggatat tgtttcatta
     3061 cagaagcgta acgaacttca cccttcaaga aaccttggaa atcttcccag ttcggttctt
     3121 tgctatccaa ttggaatggg ttcttgcctt cttcttccaa agccgggttg taacgccaca
     3181 agtgccagta accgcactta acagcttttt cttcttcttc ctggctctta cccatacctg
     3241 ctttcagacc gtggttgata cacggagcat aagcgataat caaagatggt cccggatatg
     3301 cttcagcttc acggatagct ttcagagttt gagcttggtc agcacccata gcgatctgtg
     3361 caacatatac ataaccgtaa gtagtagcca tcagaccgag gtctttctta cgtacgcgct
     3421 taccagcagc agcgaactta gcgatagcac ctaccggagt agctttagaa gactgaccac
     3481 ctgtgttaga gtaaacttca gtatccagaa cgaggatgtt aacgtcctta ccggaagcga
     3541 ttacatggtc aagaccaccg taaccgatat cgtaagaagc accgtcacca ccaatgatcc
     3601 actggctgcg ttttacaaga tattgttgca gttcagcgat ttgtttgcag tggttacatt
     3661 tatccttgtt agcttcaaca accggaatga tcttagcagc caattcctta gtcttgtccg
     3721 catccagcat attgttgatc cattcagcga acagttcttt cacttcagca ggagtgccat
     3781 cagcagcaat agcctcgttc atcactttca cgagacgagc acgcatcttt tcgttagcca
     3841 gttccatacc caaaccgaat tcacagaagt cttcgaacag tgagttagcc caagcaggac
     3901 cgtgtccgtt ttcgtttgta gtatacggag tagaaggaac agaaccagag tagatagaag
     3961 aacatccggt agcgttagca accatttcac ggtcaccgaa caattgagaa atcaatttca
     4021 cgtatggagt ttcaccacaa ccagagcaag cgccggagaa ctcaaacaac ggagtagcga
     4081 actgtgagtt cttcacgtta gccttgatat caacaagatg ttgtttagtc ttcacgtttt
     4141 cagcacagta agtccagttt tcagcttgag ccaattggct ttcgaggtgt ttcattgtca
     4201 atgctttgcc acccttcttc ggattacccg gacagatgtc agcacagtta ccgcaaccca
     4261 gacagtcgag aacgtctacc tggatacgga atgtcatacc gtcgaatgct ttacctacag
     4321 ctttcagttg ttcgaactta gcacccttct gctcttcagc gtcgagtacg aacggacgga
     4381 tagaagcgtg aggacaaacg tatgcacact tgttacactg gatacagttt tcagcattcc
     4441 attcaggaac gaatgcagct acaccacgtt tttcgtattt agcagttcct tgataccaag
     4501 taccgtcttc gatacccttg aatgcagata ccggcaacaa gtcaccgtct tgtgcattga
     4561 tcggacgaac tacttcgttg atgaatgcag gatcgttgtt ttcagctttt gcgtcatccg
     4621 gaaggttagc ccaagcagga tcaacagcca aagtcttgta ttcaccacca cggtcaacgg
     4681 cagcatagtt cttgttaaca acgtcttcac ccttcttgcc gtaagactta acgatgaatt
     4741 tcttcatctg ctcaacagct tgttctacag gaataacgcc tgtgatacgg aagaatgcag
     4801 attgaaggat tgtgttggta cggttaccca aaccaatttc cagtgcaatt tgtgttgcgt
     4861 tgatatagta tacagaaatg ttgttctgtg cgaaatattt cttaaccttg ttaggcaggt
     4921 tcttagccag ttcttcacct tcccagattg tgttcagcag gaaagaaccg ttcttacgca
     4981 aaccacgagt tacatcgtac atgtgcaggt aagcctgaac gtgacaagca acgaagttcg
     5041 gagtatttac cagataagta gaacggattg gattgtcacc gaaacgcaag tgagaacaag
     5101 tgaaaccgcc cgacttctta gagtcataag agaagtaagc ctggcagtgt ttgtcagtgt
     5161 tgtcaccgat aatctttaca gagttcttgt tagcacctac tgtaccgtca gcacccaaac
     5221 cgtagaattt agcttcgaac ataccttcgc cgcctaaagc gatttcttct ttttgaggaa
     5281 gagaagtgaa agtaacgtcg tctacgatac cgatagtgaa gtggttcttc ggcattggca
     5341 tagccaagtt ttcgaatact gaaagaattt gagcaggagt agtatctttt gaacccaaac
     5401 cgtagcgacc gccaacgata accggagcat tttctgcacc gtagaagcag tctttaacgt
     5461 caaggtaaag aggttcgccg ttagcacccg gttctttagt acggtcaaga actgcgatag
     5521 ttttagcagt cttaggtaca gcagccaaga agtgtttagc agagaacgga cgatacaggt
     5581 gtacggcaac catacccact ttttcgccgt ttgctaccag gtagtcgata gcttcgcggg
     5641 cagcttctgt tacagaaccc atagcgataa ttacgcgttc tgcatcttct gcaccatagt
     5701 aatcgaacaa accgtattta cgacctgtga tcttagaaat ttcattcatg tattcttcta
     5761 cgatagcagg aactgcttca tagtagttgt tgcatgattc acgatgttgg aagaaatggt
     5821 caggattttc agccatacca cgagctaccg gtttcatcgg gttcagtgcg cgggcacgga
     5881 attcagccaa agcttcttgg tcgatcagcg gagcaagatc atcattttcc aacatttcaa
     5941 tcttttggat ttcgtgagat gtacggaaac catcgaagaa gttcatgaac ggaacgcgag
     6001 atttgatggt agccaagtga gcaacaccag ccaaatccat aacttcctgt acagagcctt
     6061 cagccaacat agcaaagcca gtctgacgag ctgacattac gtcttggtgg tcaccgaaga
     6121 tacacaatgc gtgagaagcc aatgtacgag cagatacatg gaatacgcaa ggcaagaact
     6181 caccggcaat tttgtacatg ttagggatca tcaggagaag accctgggaa gcagtgtaag
     6241 tagtagtcaa cgcaccagcc tgaagagaac cgtgaactgc accggcagca ccaccttcag
     6301 attgcatttc ctgtactaat actgtttcgc cgaagatgtt cttacgtcct gcggcagccc
     6361 attcgtctac gtactcagcc atagtcgaag aaggagtgat ggggtagata gctgctactt
     6421 cagagaacat atacgagata tgcgctgcag cctggttacc atcacaagtg atgaatttct
     6481 tctgtttagt cataactaaa ttaaatattt aagtaaataa atcttttaat ataaaaagcc
     6541 gaacatccag agaggtatct ggttgccccg acctatttca gccttatgca acgcgtacgt
     6601 tacattcgga ttgttcttga tctttgcgcc ttcctggcaa attttgaacg gcattacttc
     6661 gtccaccata aaagagacgt ttttatctcc tttatgtacc ttatggtctt tccataaaga
     6721 atttgcaaag aatgtgtcga gcacatcctg ctcttccact ttcaccggat agatggaata
     6781 catcaggttg gagttgtgca tcattatctt tgaaggtttt ttagggaatt cttccccttt
     6841 cggataaacc agattaatga gtcgcgcatc tgccagatac ttgatatagt tcatcaccgt
     6901 ggcgcgagat gtctgtatgt cgcttgctag ttggctcaca tttggagctt tcggcccgtc
     6961 gacagcgagc aaatatagta atttttttat ctttgaaaga tatttcagtt caatttgttt
     7021 gatgagaagt atatctactt ccaccatcat gttcatcgtt ttcagcagat tctccgaaaa
     7081 gttacgcttt tcgaggaaga acggatagaa gccgtggtgc agataatcct ggaaataatc
     7141 caacggacgg actttggaga gtactccttt ggcaatctgt tcgtgagtgc taagaatttc
     7201 ttcgagactg tatgccctga atttcatgcc tgtttgcaag tttaggaatt cacggaaaga
     7261 gaatccacgc aggttatagc tcttggcgat atcacgtaat tcaagatttt cttctttcag
     7321 tcgcatcacg gacgagccgg tgaagacaat tttcaggtta ggaaaacggt cgtaacacat
     7381 gcgtaactct ttgctccatt ccggatgttt gaacacctgg tcgatcaaca atacttttcc
     7441 gccacgtttc tgaaattcgt tggcgaagtc tacaatgctg tggcccgaga aatagaagtt
     7501 gttcatgttg atgaacagac aggaacggtc gttcccgaat ttctctttgg cgtattggag
     7561 aaggaaagtg gtttttccta cgccacgtgt ccctttgata ccaatcaggc ggtcgctcca
     7621 atcgatctcg tccataagat cgcggcgaac gggggcattg gtgtgctcaa cgaggtaggc
     7681 gtgtgtgcgg tagaatgatt ccatttcagt tctttgtttt tcgggtggca aatatactgc
     7741 tttttttagg atttgcaaag tagagatggc aaaattgtgt gtttaattcc aactttctgt
     7801 ttattgtagt cattcctgac tatttcctgt atatatttgc agaataaagt tttgaattca
     7861 tttgaaatga caaaaaaggc tctttatata ttcaatccgg aacatgactt ggcgttggcc
     7921 agcggtgaaa ctaattatat ggctccagct tcggccagac gtatggcttc cgagttggct
     7981 ttgcttccga tgtggtatgc agaggagggg agtgctgtat tagcttcttc cgcttataat
     8041 ctggattatt tgaagcaaat gcaggaattg ctgggagttt cgattcattt gatgactgaa
     8101 ccggaacttg ctgtcggacc ggatttggat attcgtcctt gggggtggga tgtagctttg
     8161 cggaaacggc tttcagggct gggcgtggat gaagccctgt tgccttctat ggagcaatta
     8221 aacggtctgc gggaatactc ccatcgttct aaagccgtct cattgcttcc ggaattacaa
     8281 ctgaatgaat atttctgcgg agaatcttat tatttgaaga cacaagaaga atggaaaacc
     8341 tttgtggaag agcgggaatg ctgcctgttg aaagctccgc tttcgggaag cggtaaaggc
     8401 ttgaactggt gtaaaggcat atttactcct tttatatccg gttggtgtac gcgtgtggct
     8461 gcttcgcagg gtggaatcat tgcggaacct atatataata aggtagaaga ctttgccatg
     8521 gagttttatt ccgatggtac aggtgaagtg acatttatgg gatattccct cttccatacc
     8581 ggaaagagtg gaatgtatga agggaatcgt ttgctttcta atgaggcaat ctggaaacaa
     8641 ctttcgcaat atgtcccttc aaaggttctg acggatttgg agaactgttt gaaatataga
     8701 ctttctgcgt tggtaggaac cgtttataaa ggttatcttg gggttgatat gatgatttgt
     8761 cggtttccgg aaaatgaaaa gccggttttt cggattcatc cctgtgtgga aattaatctg
     8821 cgcatgaata tgggagttgt tgcgcgtttt ttatatgacc gttatgtacg ttctggttca
     8881 acagggcgtt ttgtgattga ttatcatcct tcggaaggtg aagccttgca ggaacatgaa
     8941 cgaatgtccg caacttatcc gttggaaatc agggaaggta gagtgtactc cggttattta
     9001 cctttggttc ctgttcatag gagaagttgc tatcgcgcat ggatatgggt aactcctgat
     9061 aatatttaac tttatctgtt cacaccagcc agcgactgat attgcgtttt tccgcactga
     9121 actctacccc gatctttatc acttcacgtc cgtctgcctg atacggtatc agatagcctt
     9181 tatcgtcgat ctgcttcaat gccgcttctg ctgtgtcatg cagcttgaat tcgaagacat
     9241 agatatattt aggtgttttc actacggcat ctgcacgacc gcgggcgctg cgtacttcgg
     9301 catcggtgaa ctgtcccata agtttgaaga caatatagaa aactacttgg tagtgacgct
     9361 ctgtctgctc gttcaattcg taggtgaaat cggcaaagaa ggcttgcagg cgggtaagaa
     9421 aggcatcgta gtctcccgaa cgaagttctt gtacaaactt gccgatgtaa aatccttggt
     9481 cactgtttct cactccggtg taaaatggaa ccaggaaatt aatgaagccg tagcggactt
     9541 catcattagg aaattgcaat agatagttac caaattccct atcgaaatct tttatcgtca
     9601 gatagccact ttggtaaatt aacggaatcg gattattgga atctacacga tattcggaga
     9661 acatggaaga cggtgcttcg atcccgtcaa gcaaagtacg caggtcgtat tcggtttctt
     9721 gcagcatctc gacgaggaaa gtcggtgtgc cggtctggaa ccagtaattg tcgaacactt
     9781 ttgatttcag gacattcagt acactgaacg ggttgaagat acctactgaa ttaatgcaaa
     9841 aatgatagcc atcgtagaga cgtgtcattc gttgtaccgc gtcatcataa gaaatggaat
     9901 tattggctgc cagtatcttg atttccggct ggaaggtatc caataattct tgaagagtga
     9961 tgccgcaaag ggttccgtaa tcgggccata aagtgatgtc ctgcaattgg ttgaggtcac
    10021 tgaatacact tacttgtgag aatttcgtta ctcctgtgag gaagacgaaa cgtaggtagc
    10081 ggtcggcact tttcaatact ccgtaaaagg ctttcagagt tttacggtat tcatccagta
    10141 agacatcatt gcctaaagct tgcaatagag gtttgtcgta ttcgtctacc agaactacga
    10201 cgctgctacc ggtttgttcg taggcacgac ggatgacgcc ggagaaacga ccggaaagag
    10261 tgttctcgtc tattcctttg ccatattgga tttcccataa ggtgagttga cggctgagga
    10321 tatcataaag tctttctggg gaatcgtact tctcggcatt taaatccaga tgcagcacag
    10381 gatgcttttc ccatttcgtt tccagttttt caatggcaag cccttcgaag agttctttct
    10441 ttccttcaaa gtaggcttca aaggtagaga gaagaagact tttaccaaaa cggcgtggac
    10501 gactcaggaa gtatggagta gatgtataag ctattttcca tacaagctct gttttatcta
    10561 catatagata atcgccctta cgaagtttct caaaggtctg tatcccgata gggagtttac
    10621 gaagcaggtc attcattgtt attttccttt tagtggttca aagataatca ttattttcgt
    10681 aatatttcgt tttcaatatc tcaaagaacg ggcgttataa ttttgtttaa ctggaaaatt
    10741 atcatttagc tcattcttgc acggttttca ccacagagga cacggaggac acagaggtga
    10801 atttgtttta tgacttacgg ttgtgaccct aattttaatg cgtaatcctc ctctataaag
    10861 ttgaaaaaac ataaaaacat ctgccacctg caaccaaacg catgtaatac agtagttaat
    10921 aagtagttag aacgtggcag atacctgcga cagataggtt gcagataaag tatctgcaac
    10981 acagtataaa ccttacataa actaattctc catgagtgct tacatttctc catagagtga
    11041 tcccaattat cccatagctt tgcataaagg aatcaaggct ttttctttga ttatataacg
    11101 tgttgcagat actttatctg caacctatct gtcgcaggta tctgccacgt tacaactgtc
    11161 tattaactag tgaattacac gcgtttcgtt gcaggtggca gatgttttta tgtttttcaa
    11221 ctttatagta ggaaaaaatt tcattcattt cagtaccttt atgagtcttt ttatccataa
    11281 ataatatcca gtcagtggta gtgcagcccc caataaggca gcaataaagg taagtatgcg
    11341 agtaaacatt cctccccagt taccaacatg cacagaataa atccaaccac gaatctttcc
    11401 cgacttgtct tgatgttgat aaagacttgt ttctgtaaat tcaccattat ccgtattgaa
    11461 agaataacgg tcagatgccc gctgattccc gaaacggttg aaagacacgc ttgccgtacc
    11521 agaagaaata ctgatttgct tatactccgg attttgacgt cttagtttat cataaatctc
    11581 ctgccaataa acgaatggtg aagttaccga gtacatatca ctgtgattgt tttccggacg
    11641 tccgcttctt tcaccctttc gaacctcatt tccttctctt ttcttttccc gatgggctgc
    11701 cagtttggta tccctctttt gagcatcact tttctgttca tgtccttggg cgacacgttg
    11761 ctgtacttcc accccgaaga ccttataaaa agccgtccga taccacggaa aagaccaggt
    11821 caatcccgtc agtgccatag ccagtagaaa gatcagagca tacattccac ctgccacatg
    11881 caagtcatac caaaaccttc tccaaccttt tgttgctgtt attttcaggc tattcttcaa
    11941 tgctttacgt gtacgcggcc accaaatgac aattcccgaa atcagtacaa aaacaagtaa
    12001 aagtgtactg acacctacaa tcattttgcc ccaaaagatc ccttcatttc ccggattcat
    12061 actatccagc agccagcgat gcattcggaa cataaacata aaaaagccgc tacgctcgct
    12121 ttttcctttt acttcacccg tatactggtc tacatacaaa gatgcacgac gtggtttgga
    12181 aagactaacc tgatacgcac gtccgggatc agaagatatg ctgacaccgg tcaccgatac
    12241 actgtcaggc aatgtcgtcg ccactttttc aagcaactta tccataggaa gaggagactc
    12301 ctttaccgtt tccacgtagt aaagatcgcg tcgaaaccac tcattcacct cattttcaaa
    12361 taccagcatg gcaccggaga agcagacaag agttattatc agtccgaaag ggacggaaag
    12421 ccacaaatgt atctttctga atattttttt catgttttca atcctatttc ttgaaaaagc
    12481 ctgcaaagct ttccgctcgg caggctttta tatacaaaag attctctatt taaccgactg
    12541 tattattttg aaagatattc catcttacct accgtagtga tagcgtcagc ttctaccgtc
    12601 aaacctttga ctgccttgcc tgtttttgcg tctattttat agaaggccgg tttctcgccc
    12661 gtagtcacag tgacagccat ataagcatag cctttttctc cataaggctc gccaccaaac
    12721 tttccgtcag ccggcagacc tgtaacaggc ataatcgtct gatcttccgc cttgaaaaca
    12781 gctaattcgc tgacatctgc acttgtaccg ccattaatca tatcttccgc tcccttttta
    12841 tacaattgaa gcaggaagta atcttcagag atgtgccagc aacggaaaat aggatgttta
    12901 gtgcctatct cttcaaagtt cacatagtaa tccggatcga aatctgttgc acctgctttg
    12961 atacgcattg cgcccgaagg cttctgtcct gttaccttct tcaaatctga agatgaaact
    13021 gccgtacgtc catatccggg agagaacaca tagacgtcac cattatcagc ggcccaaatg
    13081 gtctgataat attgtgaacg catacgaccg catgcatagc ctattttatc agtcttggca
    13141 atcaccggag tctcattaaa gttcgtgcca ttataaattg ccacgtaagc attatccggg
    13201 tattgtgtag aaggaataac accggctgta tatgcaccgc tgccgctacc accgtcagtc
    13261 ttagtcacaa gttcctgatc tgtcactgct tccggccatt ttttaatacc gtacttactc
    13321 attcccatcg ggatgacaga cgtataaatc ttattgttag cttcaaccag acctgcccat
    13381 gaaacttttt caccattacc caagtaattt tcggcaagca aggtaccctc ttcctggcta
    13441 ccatcagtcg catccagata gttgaacaac aatgcttgag ccacattctg atcctcatcc
    13501 gttattttcg agtccccggt ggaaacagtc accactttat ccccccaagt accgtatgac
    13561 gtgatacgat tataagtgta tgtgtacttt tctttcattt taccatctgc ccccagataa
    13621 taggaagctc ctgtacctgc gccaccttta ttataaacta aagcaaacac ataatccaat
    13681 cctttatata cccaataggt accgccaatc acttcggttc cattcccttg agtcgacact
    13741 gttccttcat ccaaagaatt ggctactacc aaataacttg cttcaccagt tgtggcagcc
    13801 accacataag ccgtttctcc atcaatcggc gggttatcca ccggattatt atcatcgtcg
    13861 caagatgcca caaacacacc gctactcaaa caaaaagcta cggcaaaagc ctgtaataaa
    13921 aacttcttca tatattcttt attattgatt gatactaaaa acttactctt attatttacc
    13981 gaaaaacact ctgaactttc catagaatgc gcgccccgct ttttgcaggc taaaattgtc
    14041 aaacagttgg gcatcggtga aattcctaca ttcaaatgat acattataac gtccattctt
    14101 catggtgtag gacaaagaca gattatgaga aaactgttcc ggcaccatat tctttgaatc
    14161 tttatctccg agattttccc agtaaagagg aaaatcgtgc tgccagtagc tatcatagcc
    14221 gatgctcaac acatttcctt tgacaaacag gtcattccaa taaaaatttg cattgatatt
    14281 agcataacga tagggcagat tcggcatacg cactttatag tgcatgcttt cctgcaaaga
    14341 ggaacccgcc agaaactttt cgtaatcacg agtatcgatg ctattgaatg ttcctcctat
    14401 atcaaaccaa cgcgagaagc tataaagcaa tgacaaatta taccctttgg tccttacgtg
    14461 accgtggttc tcataatatc cgtagcttgt tcctcccaat acgtccagtc ctctttttat
    14521 gtaatctttc gtatcccgat atatcaaacc ggcctcggca tacaatccat gcttgccaaa
    14581 ctgatgatta tagctgaaac tcaaattgac attatcactt ttctccggtt tcagattcat
    14641 tttgccagct tcaaggtctt catctccaaa gagttcgtcc gtggtcggca ggcggaaagc
    14701 cttttcgtac gaaagtttca cctgaagatc tttccatata aaataggtac ctgccgctcc
    14761 atatccaaga gcgcttgccg tattggacag attgatataa ttgcctattc catccgtatt
    14821 ctgcgatacc ggtcccttgt tgtattgccg ataatatttg gcaaatgccg acacattcca
    14881 tctgtccgac ggcatcagac ggtaagaaag cccgctgacg tttttacgag tgattttagg
    14941 aatagaaaag tccgtgaatt tggaagaagc accgatggta gaacggctcg tacgttcaaa
    15001 atcactgatt acaggactga aagtaagcgt atgcgcctgt ccgatatgat aattcatctt
    15061 cagcgtccca ttccagtttc tatttttaga ttcactgttc tggtaagact gttctccccg
    15121 gctacctttt tcataaaaat ctccacgcca gttgtaagcc cgcgaagcgg tatcgacatt
    15181 attggtgata ttatgattgt aattggcagt caacagcaga tccaggtttt tcaccaataa
    15241 gttctttttg taatattcta aagaagggac caacgaatgt cctttgcgga atttttcacc
    15301 gaacacgaca tcttgataaa cgcctgtttg tatctcttta tagaaatgag aataattgaa
    15361 actcaacgcc aaacgatctg cccatttctt tcctaccagg ccgatttttc caatcacggc
    15421 ttcattatga tactggtcat taaaacgttt cagatgataa atcttatttt tgtcaagtgg
    15481 cggaaaacgt acgcttccat cttctttaat ctcaaattcg cgtacataag tgtctacata
    15541 ataatcatta tccgagaaat tctgaaaagc attgacctca tacataaaac cattcttgaa
    15601 cgtttgtccg aagcgcacgt atgatttatg agtattaaat gacccgtaag aataggaagc
    15661 gtccataaac cactttccgg gttgcttgtt ggtgacaata ttaaccactc ccccaatagc
    15721 atcggttccg aatcctacag gaactactcc tttatagact tctatacggt cggcaaaatt
    15781 aataggaaca ttgttcaaat cgaatgcggc accggctccc tcctgtggta tgccgtcaat
    15841 gaagattttc acatgtttcc cgctaaagcc atcgatatac aattgcatat ccgaccccac
    15901 tccacctgat tcgcggagtt ttacaccggg cactttagtc agtgcacctg ccaaagtctg
    15961 cgtactatta tgcaatttct tcgcatcaat ggctaccgca ttaaaagcag actgattcac
    16021 acgaccgact ccggatgtcg tgaccagcac ctctcccagt tcttttaccg ccggcgcgat
    16081 agtgacgttt acttttattc tttctccctt ggctaattta actttctttt ctaccgtttg
    16141 ataaccgata gccgaaacga caagtgtata ttcaccggct gtagttttca aatgatatat
    16201 acctttttca tctgtatagc atccttggtt ggttcctttc agataaactg tcgcaaaatc
    16261 caccacttct ttctccgtgg acattactct acccgaaatt aaactattac ggtgacgccc
    16321 atgttgtgaa tatacggata cggaaaacaa gaatgccaga aaaaccaaaa aatatttatt
    16381 gctcatctcc tttttacctt tttactttat accttttcat tgctctaaaa gcgatgcaaa
    16441 ggtaagcaga aagagggatg ccaaacaatc cctatctatt ggtaaaaata aga
//
