LOCUS       c00035_gnlPro..        13423 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EFPJCCAL_35.
ACCESSION   c00035_gnlPro..
VERSION     c00035_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 23:46:57
            Original ID  :: gnl|Prokka|EFPJCCAL_35
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13423
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1470
                     /locus_tag="ctg35_1"
                     /transl_table=11
                     /translation="ELVWKIAYTSTPYFLSRPRRFGKSLLLSTFEAYFEGKKELFEGLA
                     IEKLETKWEKHPVLHLDLNAEKYDSPERLYDILSRQLTLWEIQYGKGIDENTLSGRFSG
                     VIRRAYEQTGSSVVVLVDEYDKPLLQALGNDVLLDEYRKTLKAFYGVLKSADRYLRFVF
                     LTGVTKFSQVSVFSDLNQLQDITLWPDYGTLCGITLQELLDTFQPEIKILAANNSISYD
                     DAVQRMTRLYDGYHFCINSVGIFNPFSVLNVLKSKVFDNYWFQTGTPTFLVEMLQETEY
                     DLRTLLDGIEAPSSMFSEYRVDSNNPIPLIYQSGYLTIKDFDREFGNYLLQFPNDEVRY
                     GFINFLVPFYTGVRNSDQGFYIGKFVQELRSGDYDAFLTRLQAFFADFTYELNEQTERH
                     YQVVFYIVFKLMGQFTDAEVRSARGRADAVVKTPKYIYVFEFKLHDTAEAALKQIDDKG
                     YLIPYQADGREVIKIGVEFSAEKRNISRWLV"
     protocluster    1..13423
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4056:7605](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4057..7605
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13423
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13423
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(1481..2683)
                     /locus_tag="ctg35_2"
                     /transl_table=11
                     /translation="MTKKALYIFNPEHDLALASGETNYMAPASARRMASELALLPMWYA
                     EEGSAVLASSAYNLDYLKQMQELLGVSIHLMTEPELAVGPDLDIRPWGWDVALRKRLSG
                     LGVDEALLPSMEQLNGLREYSHRSKAVSLLPELQLNEYFCGESYYLKTQEEWKTFVEER
                     ECCLLKAPLSGSGKGLNWCKGIFTPFISGWCTRVAASQGGIIAEPIYNKVEDFAMEFYS
                     DGTGEVTFMGYSLFHTGKSGMYEGNRLLSNEAIWKQLSQYVPSKVLTDLENCLKYRLSA
                     LVGTVYKGYLGVDMMICRFPENEKPVFRIHPCVEINLRMNMGVVARFLYDRYVRSGSTG
                     RFVIDYHPSEGEALQEHERMSATYPLEIREGRVYSGYLPLVPVHRRSCYRAWIWVTPDN
                     I"
     CDS             2846..4024
                     /locus_tag="ctg35_3"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGNDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLIDQVFKHPEWS
                     KELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFANSLWKDHKVHKGD
                     KNVSFMVDEVMPFKICQEGAKIKNNPNVTYALHKAEIGRGNQIPLWMFGFLY"
     CDS             4057..7605
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_4"
                     /sec_met_domain="PFOR_II (E-value: 5.5e-19, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 6.4e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 5.7e-32, bitscore: 100.6,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-12, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.3e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.2e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.3e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.4e-25, bitscore: 78.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDYLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDNPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     EQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTAKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAQAENWTYCAENVKTKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIAADGTPAEVKELFAEWINNMLDADKTKE
                     LAAKIIPVVEANKDKCNHCKQIAELQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPTEAEELFKAAEENAKW
                     RYNSYKRLARENWGAE"
     CDS             complement(7758..8624)
                     /locus_tag="ctg35_5"
                     /transl_table=11
                     /translation="MRIYKIVGIVLSAILLLASCTNSDLEKKKVKIAYANWLEGIAMSH
                     LAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEFLG
                     EVYGEARVGLVVPQYVTIQSISELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGLDG
                     YTLMTSSSSTMLASLKKAMDKGEWIVITGWTPHWMFDQFDLKFLDDPKKVYGDLEEIHA
                     IAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRQLVDSW
                     IPKSENK"
     CDS             complement(8645..9469)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.5; E-value: 8.7e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg35_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.4e-29, bitscore:
                     92.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETVINWMMVHFSTFFDAINAGIGSFIIGFQHVLFGIP
                     FYITILVLAALAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSPRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             complement(9466..10692)
                     /locus_tag="ctg35_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGNEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTTGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSRQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETHEFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             complement(10992..11330)
                     /locus_tag="ctg35_8"
                     /transl_table=11
                     /translation="MKDYKVDKASLSASFCQEVYQVVREIPVGKVSTYGGIAALLGMPQ
                     CSRMVGRALKQIPDDLSAPCHRVVNVSGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKH
                     LWNYSVPE"
     CDS             11414..12802
                     /locus_tag="ctg35_9"
                     /transl_table=11
                     /translation="MQLYLLYLQIIPTFVPIKSNPIINKTSTAVMKKKTILFASCLFGV
                     FAFSSCEKNLYDESKQPEKEIQVKDLDIPAGFQWKLTQVAAGTVAATTPTMVSFFLDEA
                     CSKEEKIADIPVDTEISSLPLSIPTYVNTLYAQYKTSTNETKKVAIPVNADRSFSLNIA
                     NDAKSKSNTTRSITRGHDIEDDIQLSKGVIFHPKDGWGTIMFEDQFPSLGDYDFNDFVV
                     NYKVQFQGIRKVDKKYTAQYIQIGLRLKAIGGIFPYSPYLRLKEIDSDEVESIEVYETK
                     NVIPAIDGVELVPNKHLIIDYSPLIKNLAKPAGSQYYNTEKNALVATSDLPEINILITL
                     KKRKEVKEILEGDEFDLYLKRNDSGTEIHMNGIEPITYQYPFNDKNLLPVYTNGDEEDD
                     NYYFSAGRLIWGLRVPGNAAHAIEKANFLEAYKGFAKWAQSSGKNEQNWYNQGNADKSL
                     LIHN"
     CDS             complement(12883..13422)
                     /locus_tag="ctg35_10"
                     /transl_table=11
                     /translation="QTCHIPVILLTACSLDEQRIQGYDGGADSYISKPFSSQLLLARVR
                     NLIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVEKFKTLIEAKMGDSNLNVEDLGKDMGL
                     SRVQLYRKIKSLTNYSPNELLRIARLKKAASLLASSDMTVAEIGYEVGFSSPSYFTKCY
                     KEQFGESPTDLLKRKG"
ORIGIN
        1 gagcttgtat ggaaaatagc ttatacatct actccatact tcctgagtcg tccacgccgt
       61 tttggtaaaa gtcttcttct ctctaccttt gaagcctact ttgaaggaaa gaaagaactc
      121 ttcgaagggc ttgccattga aaaactggaa acgaaatggg aaaagcatcc tgtgctgcat
      181 ctggatttaa atgccgagaa gtacgattcc ccagaaagac tttatgatat cctcagccgt
      241 caactcacct tatgggaaat ccaatatggc aaaggaatag acgagaacac tctttccggt
      301 cgtttctccg gcgtcatccg tcgtgcctac gaacaaaccg gtagcagcgt cgtagttctg
      361 gtagacgaat acgacaaacc tctattgcaa gctttaggca atgatgtctt actggatgaa
      421 taccgtaaaa ctctgaaagc cttttacgga gtattgaaaa gtgccgaccg ctacctacgt
      481 ttcgtcttcc tcacaggagt aacgaaattc tcacaagtaa gtgtattcag tgacctcaac
      541 caattgcagg acatcacttt atggcccgat tacggaaccc tttgcggcat cactcttcaa
      601 gaattattgg ataccttcca gccggaaatc aagatactgg cagccaataa ttccatttct
      661 tatgatgacg cggtacaacg aatgacacgt ctctacgatg gctatcattt ttgcattaat
      721 tcagtaggta tcttcaaccc gttcagtgta ctgaatgtcc tgaaatcaaa agtgttcgac
      781 aattactggt tccagaccgg cacaccgact ttcctcgtcg agatgctgca agaaaccgaa
      841 tacgacctgc gtactttgct tgacgggatc gaagcaccgt cttccatgtt ctccgaatat
      901 cgtgtagatt ccaataatcc gattccgtta atttaccaaa gtggctatct gacgataaaa
      961 gatttcgata gggaatttgg taactatcta ttgcaatttc ctaatgatga agtccgctac
     1021 ggcttcatta atttcctggt tccattttac accggagtga gaaacagtga ccaaggattt
     1081 tacatcggca agtttgtaca agaacttcgt tcgggagact acgatgcctt tcttacccgc
     1141 ctgcaagcct tctttgccga tttcacctac gaattgaacg agcagacaga gcgtcactac
     1201 caagtagttt tctatattgt cttcaaactt atgggacagt tcaccgatgc cgaagtacgc
     1261 agcgcccgcg gtcgtgcaga tgccgtagtg aaaacaccta aatatatcta tgtcttcgaa
     1321 ttcaagctgc atgacacagc agaagcggca ttgaagcaga tcgacgataa aggctatctg
     1381 ataccgtatc aggcagacgg acgtgaagtg ataaagatcg gggtagagtt cagtgcggaa
     1441 aaacgcaata tcagtcgctg gctggtgtga acagataaag ttaaatatta tcaggagtta
     1501 cccatatcca tgcgcgatag caacttctcc tatgaacagg aaccaaaggt aaataaccgg
     1561 agtacactct accttccctg atttccaacg gataagttgc ggacattcgt tcatgttcct
     1621 gcaaggcttc accttccgaa ggatgataat caatcacaaa acgccctgtt gaaccagaac
     1681 gtacataacg gtcatataaa aaacgcgcaa caactcccat attcatgcgc agattaattt
     1741 ccacacaggg atgaatccga aaaaccggct tttcattttc cggaaaccga caaatcatca
     1801 tatcaacccc aagataacct ttataaacgg ttcctaccaa cgcagaaagt ctatatttca
     1861 aacagttctc caaatccgtc agaacctttg aagggacata ttgcgaaagt tgtttccaga
     1921 ttgcctcatt agaaagcaaa cgattccctt catacattcc actctttccg gtatggaaga
     1981 gggaatatcc cataaatgtc acttcacctg taccatcgga ataaaactcc atggcaaagt
     2041 cttctacctt attatatata ggttccgcaa tgattccacc ctgcgaagca gccacacgcg
     2101 tacaccaacc ggatataaaa ggagtaaata tgcctttaca ccagttcaag cctttaccgc
     2161 ttcccgaaag cggagctttc aacaggcagc attcccgctc ttccacaaag gttttccatt
     2221 cttcttgtgt cttcaaataa taagattctc cgcagaaata ttcattcagt tgtaattccg
     2281 gaagcaatga gacggcttta gaacgatggg agtattcccg cagaccgttt aattgctcca
     2341 tagaaggcaa cagggcttca tccacgccca gccctgaaag ccgtttccgc aaagctacat
     2401 cccaccccca aggacgaata tccaaatccg gtccgacagc aagttccggt tcagtcatca
     2461 aatgaatcga aactcccagc aattcctgca tttgcttcaa ataatccaga ttataagcgg
     2521 aagaagctaa tacagcactc ccctcctctg cataccacat cggaagcaaa gccaactcgg
     2581 aagccatacg tctggccgaa gctggagcca tataattagt ttcaccgctg gccaacgcca
     2641 agtcatgttc cggattgaat atataaagag ccttttttgt catttcaaat gaattcaaaa
     2701 ctttattctg caaatatata caggaaatag tcaggaatga ctacaataaa cagaaagttg
     2761 gaattaaaca cacaattttg ccatctctac tttgcaaatc ctaaaaaaag cagtatattt
     2821 gccacccgaa aaacaaagaa ctgaaatgga atcattctac cgcacacacg cctacctcgt
     2881 tgagcacacc aatgcccccg ttcgccgcga tcttatggac gagatcgatt ggagcgaccg
     2941 cctgattggt atcaaaggga cacgtggcgt aggaaaaacc actttccttc tccaatacgc
     3001 caaagagaaa ttcgggaacg accgttcctg tctgttcatc aacatgaaca acttctattt
     3061 ctcgggccac agcattgtag acttcgccaa cgaatttcag aaacgtggcg gaaaagtatt
     3121 gttgatcgac caggtgttca aacatccgga atggagcaaa gagttacgca tgtgttacga
     3181 ccgttttcct aacctgaaaa ttgtcttcac cggctcgtcc gtgatgcgac tgaaagaaga
     3241 aaatcttgaa ttacgtgata tcgccaagag ctataacctg cgtggattct ctttccgtga
     3301 attcctaaac ttgcaaacag gcatgaaatt cagggcatac agtctcgaag aaattcttag
     3361 cactcacgaa cagattgcca aaggagtact ctccaaagtc cgtccgttgg attatttcca
     3421 ggattatctg caccacggct tctatccgtt cttcctcgaa aagcgtaact tttcggagaa
     3481 tctgctgaaa acgatgaaca tgatggtgga agtagatata cttctcatca aacaaattga
     3541 actgaaatat ctttcaaaga taaaaaaatt actatatttg ctcgctgtcg acgggccgaa
     3601 agctccaaat gtgagccaac tagcaagcga catacagaca tctcgcgcca cggtgatgaa
     3661 ctatatcaag tatctggcag atgcgcgact cattaatctg gtttatccga aaggggaaga
     3721 attccctaaa aaaccttcaa agataatgat gcacaactcc aacctgatgt attccatcta
     3781 tccggtgaaa gtggaagagc aggatgtgct cgacacattc tttgcaaatt ctttatggaa
     3841 agaccataag gtacataaag gagataaaaa cgtctctttt atggtggacg aagtaatgcc
     3901 gttcaaaatt tgccaggaag gcgcaaagat caagaacaat ccgaatgtaa cgtacgcgtt
     3961 gcataaggct gaaataggtc ggggcaacca gatacctctc tggatgttcg gctttttata
     4021 ttaaaagatt tatttactta aatatttaat ttagttatga ctaaacagaa gaaattcatc
     4081 acttgtgatg gtaaccaggc tgcagcgcat atctcgtata tgttctctga agtagcagct
     4141 atctacccca tcactccttc ttcgactatg gctgagtacg tagacgaatg ggctgccgca
     4201 ggacgtaaga acatcttcgg cgaaacagta ttagtacagg aaatgcaatc tgaaggtggt
     4261 gctgccggtg cagttcacgg ttctcttcag gctggtgcgt tgactactac ttacactgct
     4321 tcccagggtc ttctcctgat gatccctaac atgtacaaaa ttgccggtga gttcttgcct
     4381 tgcgtattcc atgtatctgc tcgtacattg gcttctcacg cattgtgtat cttcggtgac
     4441 caccaagacg taatgtcagc tcgtcagact ggctttgcta tgttggctga aggctctgta
     4501 caggaagtta tggatttggc tggtgttgct cacttggcta ccatcaaatc tcgcgttccg
     4561 ttcatgaact tcttcgatgg tttccgtaca tctcacgaaa tccaaaagat tgaaatgttg
     4621 gaaaatgatg atcttgctcc gctgatcgac caagaagctt tggctgaatt ccgtgcccgc
     4681 gcactgaacc cgatgaaacc ggtagctcgt ggtatggctg aaaatcctga ccatttcttc
     4741 caacatcgtg aatcatgcaa caactactat gaagcagttc ctgctatcgt agaagaatac
     4801 atgaatgaaa tttctaagat cacaggtcgt aaatacggtt tgttcgatta ctatggtgca
     4861 gaagatgcag aacgcgtaat tatcgctatg ggttctgtaa cagaagctgc ccgcgaagct
     4921 atcgactacc tggtagcaaa cggcgaaaaa gtgggtatgg ttgccgtaca cctgtatcgt
     4981 ccgttctctg ctaaacactt cttggctgct gtacctaaga ctgctaaaac tatcgcagtt
     5041 cttgaccgta ctaaagaacc gggtgctaac ggcgaacctc tttaccttga cgttaaagac
     5101 tgcttctacg gtgcagaaaa tgctccggtt atcgttggcg gtcgctacgg tttgggttca
     5161 aaagatacta ctcctgctca aattctttca gtattcgaaa acttggctat gccaatgccg
     5221 aagaaccact tcactatcgg tatcgtagac gacgttactt tcacttctct tcctcaaaaa
     5281 gaagaaatcg ctttaggcgg cgaaggtatg ttcgaagcta aattctacgg tttgggtgct
     5341 gacggtacag taggtgctaa caagaactct gtaaagatta tcggtgacaa cactgacaaa
     5401 cactgccagg cttacttctc ttatgactct aagaagtcgg gcggtttcac ttgttctcac
     5461 ttgcgtttcg gtgacaatcc aatccgttct acttatctgg taaatactcc gaacttcgtt
     5521 gcttgtcacg ttcaggctta cctgcacatg tacgatgtaa ctcgtggttt gcgtaagaac
     5581 ggttctttcc tgctgaacac aatctgggaa ggtgaagaac tggctaagaa cctgcctaac
     5641 aaggttaaga aatatttcgc acagaacaac atttctgtat actatatcaa cgcaacacaa
     5701 attgcactgg aaattggttt gggtaaccgt accaacacaa tccttcaatc tgcattcttc
     5761 cgtatcacag gcgttattcc tgtagaacaa gctgttgagc agatgaagaa attcatcgtt
     5821 aagtcttacg gcaagaaggg tgaagacgtt gttaacaaga actatgctgc cgttgaccgt
     5881 ggtggtgaat acaagacttt ggctgttgat cctgcttggg ctaaccttcc ggatgacgca
     5941 aaagctgaaa acaacgatcc tgcattcatc aacgaagtag ttcgtccgat caatgcacaa
     6001 gacggtgact tgttgccggt atctgcattc aagggtatcg aagacggtac ttggtatcaa
     6061 ggaactgcta aatacgaaaa acgtggtgta gctgcattcg ttcctgaatg gaatgctgaa
     6121 aactgtatcc agtgtaacaa gtgtgcatac gtttgtcctc acgcttctat ccgtccgttc
     6181 gtactcgacg ctgaagagca gaagggtgct aagttcgaac aactgaaagc tgtaggtaaa
     6241 gcattcgacg gtatgacatt ccgtatccag gtagacgttc tcgactgtct gggttgcggt
     6301 aactgtgctg acatctgtcc gggtaatccg aagaagggtg gcaaagcatt gacaatgaaa
     6361 cacctcgaaa gccaattggc tcaagctgaa aactggactt actgtgctga aaacgtgaag
     6421 actaaacaac atcttgttga tatcaaggct aacgtgaaga actcacagtt cgctactccg
     6481 ttgtttgagt tctccggcgc ttgctctggt tgtggtgaaa ctccatacgt gaaattgatt
     6541 tctcaattgt tcggtgaccg tgaaatggtt gctaacgcta ccggatgttc ttctatctac
     6601 tctggttctg ttccttctac tccgtatact acaaacgaaa acggacacgg tcctgcttgg
     6661 gctaactcac tgttcgaaga cttctgtgaa ttcggtttgg gtatggaact ggctaacgaa
     6721 aagatgcgtg ctcgtctcgt gaaagtgatg aacgaggcta ttgctgctga tggcactcct
     6781 gctgaagtga aagaactgtt cgctgaatgg atcaacaata tgctggatgc ggacaagact
     6841 aaggaattgg ctgctaagat cattccggtt gttgaagcta acaaggataa atgtaaccac
     6901 tgcaaacaaa tcgctgaact gcaacaatat cttgtaaaac gcagccagtg gatcattggt
     6961 ggtgacggtg cttcttacga tatcggttac ggtggtcttg accatgtaat cgcttccggt
     7021 aaggacgtta acatcctcgt tctggatact gaagtttact ctaacacagg tggtcagtct
     7081 tctaaagcta ctccggtagg tgctatcgct aagttcgctg ctgctggtaa gcgcgtacgt
     7141 aagaaagacc tcggtctgat ggctactact tacggttatg tatatgttgc acagatcgct
     7201 atgggtgctg accaagctca aactctgaaa gctatccgtg aagctgaagc atatccggga
     7261 ccatctttga ttatcgctta tgctccgtgt atcaaccacg gtctgaaagc aggtatgggt
     7321 aagagccagg aagaagaaga aaaagctgtt aagtgcggtt actggcactt gtggcgttac
     7381 aacccggctt tggaagaaga aggcaagaac ccattccaat tggatagcaa agaaccgaac
     7441 tgggaagatt tccaaggttt cttgaagggt gaagttcgtt acgcttctgt aatgaaacaa
     7501 tatcctactg aagctgaaga actgttcaaa gctgctgaag aaaacgctaa atggcgttac
     7561 aacagctaca aacgtttggc tagagaaaac tggggtgctg aataatagta ataccctata
     7621 aatataaaac ggtaatcttg tagaagatta ccgttttttt attgtatgaa ctctgtctaa
     7681 cataaacaat actccctttt tcccactaga gttcatgtct attttatatt taaaattaag
     7741 aataacaatg ctccaatcta tttattctca gacttcggaa tccaactatc caccaactgc
     7801 cgatgttcat ccctccattt gcgggctatt tcttcttcat ccatccgggc atccttcata
     7861 gctgtcataa aagagctaag ttcttctgtc gttagtttaa tgttgccaaa gaattcggca
     7921 gcaaacggat ctttctcact gaatcctttc catgcaatag catgtatttc ttccaagtct
     7981 ccatatactt tcttcggatc atccaagaat ttcaagtcaa actggtcgaa catccaatgc
     8041 ggtgtccacc ccgtgatgac aatccattct cctttgtcca tcgctttttt caaagaagcc
     8101 agcatggtgg aactacttga agtcatgagg gtatacccat caagtccata agcagcaatg
     8161 gccttatcgg tcgtcttcat tatccctgct ccggcatcaa ttcccactat ttcggaagag
     8221 aaacggtctt tattagcttc cagctcacta atagactgaa tcgtaacata ttgaggaaca
     8281 accagcccta cacgggcttc tccatatacc tcacccagaa attcgatgct gtctccatac
     8341 tgatccatat aatctttcat cgttattggt aaccaggcat ccagaaacac atctgatttc
     8401 tttcctgaca tagatacaaa aataggggca agatcagcat tttgcaattc aacctcatat
     8461 ccatgttctt ccaataccac cttagccaaa tggctcatgg caataccttc caaccaattg
     8521 gcataggcta tttttacttt ctttttctct aagtctgaat tagtacagga agccagcaaa
     8581 agtatagctg acaatactat tcctactatt ttatatattc tcatacgtat tttatccttt
     8641 ccgtttagtt cttgtttttt cgtcctgcca ttccttgtgt gatacggtct aagatgatag
     8701 ctaaaataac aactgcgata ccaccttcaa acccaagtcc gattttcatt tgggtaatac
     8761 ctttcaatac aatttctccc agaccaccgg cagcaatcat ggcagcaatg acaaccatag
     8821 aaagcgacat cattattgtc tgattgacac ctgtcaggat ggttggcaac gccaaaggaa
     8881 gctgcacttt atacaataac tgccaacggg tagccccgaa cgaacgggaa gcttccacta
     8941 catttttagg aacttgccga attcccaatc cagtaaggcg gaccacagga ggcatagcaa
     9001 agataatggt ggcaaacact cccggcactg ctcccaatcc gaaaaacaaa acggcaggaa
     9061 tcagataaac aaaagcaggc atcgtctgca ttaagtcgag aacaggacga agtattttct
     9121 ctgcacgcgg actgtttgcc gtccacactc ctaaaggtac accaacaatc agggccagac
     9181 aggtagatga aaaaacaaga gccagggttt gcatagtagc ctcccaaaat cccattccat
     9241 aaatcagtaa taatcccaat gcggtgaaaa ttgccgtacc acgtcctgcc ttcatccatg
     9301 cgagtgcagc aagcactaga atggttatat aaaaaggtat tccaaaaagt acgtgttgga
     9361 atcctataat aaaactaccg atgcctgcat ttatggcatc aaagaaagtg gaaaaatgta
     9421 ccatcatcca attgatgacc gtctctatat attgtcctat atttatcata aatctattgc
     9481 gttttgaatt atttcgttta tttcttcttt atctttcccc gtcacttcga tgattaagga
     9541 ggaaagcggg attgttccta aaaactcatg cgtctcatca atcacccata ccggcgaatt
     9601 gctctttgtc attaaaggaa gtatatcctc caacactgta tcctccaata cagaatgtac
     9661 ttcggtacgc acaatcgttt caatggattt ttcctgtctg ctacgtaact taagcaggtc
     9721 gttcagacgt acttctccga ccagtttatc atcggcgtct atgacaggta atacggtgat
     9781 attcttcgca cgcatcttac gaatcaatac ttcaggtccc tctttcttca gacgggccac
     9841 cagtggtttg tcaatcatta aagaagaagc ggtaataatt ttactcctgt ccacgttttc
     9901 aacaaaacgg gctacataat cgttagccgg ttcggtcagt atttcttctg aagtacctac
     9961 ctgcaccacc tctccgtctt tcataatagc aatacggtcg cccagtttaa tcgcttcact
    10021 caagtcatgg gtaataaaga caattgtttt tttcatcttc gactgcaaag ccagcagttc
    10081 atcctgcatt tgcacacgaa tcagaggatc gagcgcagag aaagcctcat ccattagaag
    10141 tacttcggga ttattagcca gagcgcgggc cagtccgaca cgctgttgca ttccaccgga
    10201 aagctcgccc accatctgat tttcatatcc tttcaatccg acaagcttca tgctttccat
    10261 cgctttcttc tcacgttcct ctttcttcac tccctgaagt tcgaggccga acgcgatatt
    10321 gctcaatacg gaacggtgag gtaacagacc gaaattctgg aaaaccatcg ccagctcttt
    10381 ccgacgaacc tgcaataatt ctttttcgga aattttagat atatctactc cgtttacaag
    10441 cacttgcccg gtagtaggac gtatcagacg attgatacaa cgcagtaatg tcgattttcc
    10501 acttcccgag agtcccatta tcacgaaaaa ctctccttca ttaattgaaa gattggcatc
    10561 tttcactcct accgtacaac cggtatcttt cagaatttcc tctttactct tatctttttt
    10621 caacatcttg agggctttct gcttctcgtt accaaagata aggtacaaat cctttatttc
    10681 tattttactc atataatata ttggtttaga ttataatatt tgttttgttt tcaactgccg
    10741 cattccttat tctcacttac gataaacaag ttgaatgttc gcatggttca gtcatgtcac
    10801 atgataacat gacggtccga cgttttttaa atggtttaaa aaaaacagac agagtagttt
    10861 aaaaggaata gaatttgata agattatcct cttaatgaac agtagaaaac agtattttca
    10921 taaataaata acagtctgtt cttgcatatt gttggcacaa aggtaaggaa aatagattaa
    10981 atatgcaaat ttcattcagg tacggagtaa ttccaaagat gctttttcaa gtctacgcat
    11041 ccattttgtt tgaaagagat cccttcttcc aacaagagtt gtttctgctc tgtccaaccc
    11101 ggaacaaggc gtcccgatac attgacaacc cgatgacaag gcgcagataa atcatccgga
    11161 atctgtttca aagcacgccc caccatacgg gaacattgag gcattcccaa taatgcggca
    11221 attcccccat aggtagaaac tttacctacc ggaatttccc gaacaacctg atacacctct
    11281 tgacaaaagg atgcggagag actcgctttg tctactttat aatctttcat cactcaaaca
    11341 ttactttatt tcagttccaa aactagataa aaaggaaaga atttgcaaat aataaaagta
    11401 tttcaaataa aatatgcaac tttatttgct ttatttacaa ataatcccga cctttgtacc
    11461 cattaaaagc aaccctatta ttaacaaaac aagcactgct gttatgaaaa agaagacaat
    11521 tctattcgct tcttgtttat ttggagtatt cgctttcagc tcctgtgaga agaaccttta
    11581 tgatgaaagc aagcaacctg aaaaagaaat tcaagtaaaa gacctggata tacccgcagg
    11641 ctttcaatgg aaattaactc aagtagccgc aggaacagta gctgctacta cccccactat
    11701 ggtttccttc tttttggatg aagcatgtag taaagaagag aaaatagccg acattcctgt
    11761 agatacagaa atttcaagtc tccctttgag catcccaacc tacgtaaata cattgtatgc
    11821 ccagtacaaa accagcacca atgaaaccaa aaaagtagcc atacctgtaa atgcagatag
    11881 aagtttctca ctgaacattg ctaatgatgc caaatccaaa tctaacacca cccggtcaat
    11941 cactcgtggg catgatatag aagatgacat ccaattgtca aaaggagtca tttttcatcc
    12001 caaagatggt tggggaacaa tcatgtttga agaccaattt ccatcattag gagattatga
    12061 ctttaatgat tttgtagtca attataaggt gcagttccaa ggtattagaa aggttgacaa
    12121 aaaatacact gcgcagtata tacaaatagg gttacgtcta aaagctatcg gaggaatatt
    12181 cccttattcc ccttatttaa gactgaaaga aatagattct gacgaagtgg aaagtataga
    12241 agtttatgaa actaaaaacg tgattcctgc gatcgacgga gtagaacttg tccccaataa
    12301 acatcttatc attgattaca gccctttaat taagaatctg gctaaacctg caggcagcca
    12361 atattataat acagaaaaga atgctttggt agcaacaagt gatttaccgg agatcaatat
    12421 tctgatcacc ctaaaaaaga gaaaagaagt aaaggaaata ttagaaggcg atgaattcga
    12481 cttgtattta aaacgtaatg atagcggaac agaaatccat atgaatggta ttgaaccgat
    12541 cacttaccaa tatccattca atgataaaaa tctgctaccg gtatatacaa acggggacga
    12601 agaagatgat aattattatt ttagtgcagg acgcctgatt tggggattaa gagtaccagg
    12661 caacgcagca catgctattg aaaaagctaa tttcttggaa gcctataaag gattcgcaaa
    12721 atgggcgcaa agtagtggca aaaacgaaca aaactggtat aatcaaggaa acgcagataa
    12781 aagtttattg attcataact aacacatatc aataaatccc ggtaaacatt gaaaattcaa
    12841 gttaccggga tttattgtat tctgacgtga atagttttga ttctatcctt tccttttcag
    12901 caaatctgtc ggactttcgc caaactgctc tttatagcat ttggtaaaat aagaaggaga
    12961 actaaaaccg acttcataac caatctccgc cactgtcata tccgacgaag caagcaagga
    13021 agcagctttc tttaaacgag cgatacgaag caattcattc ggagaataat tagtcaaaga
    13081 ttttattttg cgatagagct gcacacgact taatcccata tccttaccca aatcttctac
    13141 attcaaattt gagtctccca tctttgcttc aatcaaagtc ttgaattttt ccacaaagtc
    13201 tttatccata tcgcaaacat cctctttcgc caacgtttgt ccgtcaccaa agaactgttt
    13261 caggcggcga tgtgaatcta tcagattacg aacgcgtgcc aacagcaatt gcgaactgaa
    13321 gggcttggag atataagaat ccgcacctcc gtcatatccc tgaatccgtt gttcatccaa
    13381 agaacaggct gtcaataaga tgacagggat atggcaggtt tgc
//
