LOCUS       c00855_gnlPro..        14894 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ACIBFKND_855.
ACCESSION   c00855_gnlPro..
VERSION     c00855_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 00:36:51
            Original ID  :: gnl|Prokka|ACIBFKND_855
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14894
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14894
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3133:13334]"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3134..13334
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
     cand_cluster    1..14894
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /kind="single"
                     /product="NADH_dehydrogenase_I"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14894
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NADH_dehydrogenase_I"
                     /region_number="1"
                     /rules="(Oxidored_q4 and Oxidored_q6 and Complex1_30kDa and
                     Complex1_49kDa and NADHdh and Oxidored_q3 and Oxidored_q2
                     and minimum(4, [Fe-2S_thioredx, Fer2_4, Fer4_7,
                     Molybdop_Fe4S4, Molydop_binding, NADH-G_4Fe-4S_3,
                     NADH_4Fe-4S, Proton_antipo_M, Proton_antipo_N, SLBB]))"
                     /tool="gutsmash"
     CDS             183..2993
                     /locus_tag="ctg855_1"
                     /transl_table=11
                     /translation="MQTDNERYRKMASLAQIGWWEVDLTAGYYLCSDYLSDLLGLDGDT
                     ISTSDFLNLIREDYRKQIAQEFRANSSIHKDFYEQTFPIHSKYGEVWLHTRLAFREKGT
                     GVDGGDKSFGIIQRVEAPKEEDQRDALRRVNDLLCRQNFVSQSLLRFLRDEAVESCIAD
                     ILRDILNLYNGKGRVYIFEYDEIYAHHSCIYEVVSEGVSAEIDNLQDMPASESKWWSEQ
                     ILSGKPIILNTLEQLLEEAPDEYQILVVQGIKSLMVTPLMTGDRVWGYMGIDLVETYHD
                     WSNEDFQWFSSLGNIINICIELRKTKDKVIREQTFLNNLFHFMPMGYIRMSIIRDENNK
                     PCDYRVTDANEVSSTFFGLPLESYIGSLASEKHPDYLQKLNFLEEILDSNSYREKDEYF
                     PRTERYTHWVIYSPGKDEIVGLFLDSTGSVQANRALDRSEKLFKNIFANIPAGVEIYDK
                     DGYLIDLNNKDLEIFGVVNKSDVIGVNFFENPNVPQGIRDRVRNEDLVDFRLNYSFEQA
                     GGYYETSRSNVIELYSKVSKLYDNEGNFSGYILISIDNTERIDAMNRIRDFENFFLMIS
                     DYAKVGYAKLNLLNRKGYAIKQWYKNLGEEEDIPLSEVVAVYSQMHPEDRKRFLDFYDG
                     VRDGKRRHFQGEMRIRRPGTKNEWNWVSSNVMVTNYKPEENEIEIIGINYDITELKETE
                     AELIQARDKAEMMDRLKSAFLANMSHEIRTPLNAIVGFSDLLVETEELAERQEYIKIVR
                     ENNELLLQLISDILDLSKIEAGTFEFTNGDVDVNLLCEDIVRSMGMKAKEEVELVFDDH
                     LPVCHVISDRNRIHQVISNFVNNAMKFTSEGSIHVGYKLKDGELEFYVEDTGIGIEKEQ
                     LPHIFERFVKLNSFVHGTGLGLSICQSIVEQLGGRIGVDSEKGKGSRFWFTIPGVIVTE
                     EMNCAR"
     CDS             complement(3134..4573)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg855_2"
                     /sec_met_domain="Proton_antipo_M (E-value: 5.4e-73,
                     bitscore: 235.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYSQFLNMREELSLIAVLLLLFLADLFMSPDAHKNSGKARLNTM
                     LPVILMAIHTAINLIPGTAADAFGGMYHYVPMHTVVKSILNVGTLIVFLMAHEWMKRED
                     TSFKQGEFYVLTLSTLFGMYLMISAGHFLMFFIGLETASIPMAALIAFDKYRHNSAEAG
                     AKYILTALFSSALLLFGLSMIYGSAGTLYFDDLPAHIDGNPLQIMAFIFFFTGMAFKLS
                     LVPFHLWTADVYEGAPSTVTAYLSVISKGSAAFVLLAILIKVFAPMINDWQEVLYWVTI
                     ASITIANIFAVRQQNLKRLMAFSSISQAGYIMLGVIGGTAQGMTALVYYVLVYAAANLG
                     VFAVITIVALRSQKFTLEDYAGLYKTNPKIALLMTLSLFSLAGIPPFAGFFSKFFIFMA
                     AFDAGFHLLVFIALVNTVISLYYYLLIVKAMYITPSDNPIPTFRSDRCTKWGLALCTLG
                     IIGLGIASIVYQSIDKLSFGI"
     CDS             complement(4611..6095)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg855_3"
                     /sec_met_domain="Proton_antipo_M (E-value: 2.2e-68,
                     bitscore: 220.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFLSIFVLIPLLMLAGLWAARGIKAIRGVMVTGASALLIASVVL
                     TFLYLGERSAGNTAEMLFRADTLWYAPLHISYSVGVDGISVAMLLLSAVIVFTGTFASW
                     RLQPLTKEYFLWFTLLSMGVFGFFISVDLFTMFMFYEIALIPMYLLIGVWGSGRKEYAA
                     MKLTLMLMGGSAFLLIGILGIYFGSGATTMNLLEIAQLHNIPFAQQCIWFPLTFLGFGV
                     LGALFPFHTWSPDGHASAPTAVSMLHAGVLMKLGGYGCFRIAMYLMPEAANELSWIFLI
                     LTGISVVYGAFSACVQTDLKYINAYSSVSHCGLVLFAILMLNQTAATGAILQMLSHGLM
                     TALFFALIGMIYGRTHTRDVRELAGLMKIMPFLSVCYVIAGLANLGLPGLSGFIAEMTI
                     FVGSFQNNDVFHRTLTIIACSSIVITAVYILRLVGKILYGTCTNKHHLELTDATWDERV
                     AVICLIVCVAGLGMAPFWVSHMIGESVLPVVSQLIP"
     CDS             complement(6134..8065)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg855_4"
                     /sec_met_domain="Proton_antipo_N (E-value: 2.3e-25,
                     bitscore: 78.5, seeds: 433, tool: rule-based-clusters)"
                     /sec_met_domain="Proton_antipo_M (E-value: 1.9e-87,
                     bitscore: 283.0, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTILILLLPFFSFLILGIGGKWMSHRTAGTIGTLILGAVAVLS
                     YVTAIQYFSAPPLEDGTFATLMPYNFTWLPFTETLHFDLGILLDPISVMMLIVISTVSL
                     MVHIYSFGYMKGEVGFQRYYAFLSLFTMSMLGLVVATNIFQMYLFWELVGVSSYLLIGF
                     YYTKPAAIAASKKAFIVTRFADLGFLIGILIYGYYGGTFGFTPDTVSLISGGASMLPLA
                     LGLMFVGGAGKSAMFPLHIWLPDAMEGPTPVSALIHAATMVVAGVYLVARMFPLFITYA
                     PNTLHMVAWVGAFTAFYAASVACVQSDIKRVLAFSTISQIGFMMVALGVCTSMNPHEGG
                     LGYMASMFHLFTHAMFKALLFLGAGSIIHAVHSNEMSAMGGLRKYMPITHWTFLIACLA
                     IAGIPPFSGFFSKDEILAACFQYSPVMGWVMTVIAAMTAFYMFRLYYGIFWGSEPPRAG
                     SHSEHNTPHGNLEAAPCRPHESPLAMTFPLMFLAVVTCGAGFIPFGHFISSNGESYSIH
                     LDPSVAITSVVIAIISIAIATWMYKNAKQPVADSLAKRFKGLHKAAYNRFYIDDIYQFI
                     THKIIFRCISTPIAWFDRHVVDGFFDFLAWATNTTSDEIRGLQSGQVQQYAYVFLCGAL
                     ALILLLIL"
     CDS             complement(8257..8565)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg855_5"
                     /sec_met_domain="Oxidored_q2 (E-value: 3.1e-22, bitscore:
                     68.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHMEYYLVVSTIMMFAGIYGFFTRRNTLAILISVELMLNATDIN
                     FAVFNRFLFPGGMEGYFFALFSIAISAAETAIAIAIMINIYRNLRSIQVRNLDELKW"
     CDS             complement(8603..9115)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg855_6"
                     /sec_met_domain="Oxidored_q3 (E-value: 4.9e-38, bitscore:
                     120.0, seeds: 708, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSTLETVVFYFLAAFIIAMSIMTVTTQRIVRSATYLLFVLFGTA
                     GIYFLLGYTFLGSVQIMVYAGGIVVLYVFSILLTSGEGDRAEKAKRSKVLAGLFTMIAG
                     LAIILFITLKHDFMQTANLAPQEISIHAIGNALLSSDKYGYVLPFEAVSILLLACIIGG
                     IMIARKR"
     CDS             complement(9118..9606)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg855_7"
                     /sec_met_domain="Fer4_7 (E-value: 3.6e-13, bitscore: 39.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.1e-05, bitscore: 15.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYKDKKYTYLGGLVHGISTLATGMKTSIKVYFRKKVTEQYPENR
                     KELKMFDRFRGTLNMPHNENNEHRCVACGLCQMACPNDTIKVTSETVETEDGKKKKILA
                     TYEYDLGACMFCQLCVNACPHDAITFDQNFEHAVFDRTKLVLKLNHDGSKVIEKKKEV"
     CDS             complement(9619..10695)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: NADHdh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg855_8"
                     /sec_met_domain="NADHdh (E-value: 4.3e-123, bitscore:
                     400.2, seeds: 435, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDFSIVTNWIHELLLSIMPEGLAIFIECVAVGVCLVALYAILAI
                     ILIYMERKVCGFFQCRLGPNRVGKWGSIQVVCDVLKMLTKEIFMPKGADHFLYNLAPFM
                     VIIASFLTFACIPFNKGAAILDFNVGVFFLLAASSIGVVGILLAGWGSNNKFSLIGAMR
                     SGAQIISYELSVGMSIMTMVVLTGTMQFSEIVEGQANGWFIFKGHIPAVIAFIIYLIAG
                     NAECNRGPFDLPEAESELTAGYHTEYSGMGFGFFYLAEYLNLFIVASVAATIFLGGWMP
                     LHIVGLDGFNTVMDYIPGFIWFFAKAFFVVFLLMWIKWTFPRLRIDQILNLEWKYLVPI
                     SMVNLLLMACCVAFGFHF"
     CDS             complement(10716..12308)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_49kDa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_30kDa"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg855_9"
                     /sec_met_domain="Complex1_30kDa (E-value: 1.2e-36,
                     bitscore: 115.9, seeds: 586, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_49kDa (E-value: 9.3e-66,
                     bitscore: 211.5, seeds: 265, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQEIQFIAPAALHDEMLRLRNEKQMDFLESLTGMDWGVADEKDAP
                     EKLRGLGVVYHLESTITGERIALKTATTNRELPEIPSVSDIWKIADFYEREVFDFYGIT
                     FVGHPDMRRLYLRNDWIGYPMRKDNDPEKDNPLCMTNEKTFDTTQEIELNPDGTIKNKE
                     TKLFGEEEYVVNIGPQHPATHGVMRFRVSLEGEIIRKIDANCGYIHRGIEKMNESLTYP
                     QTLALTDRLDYLGAHQNRHALCMCIEKAMGIEVSERVQYIRTIMDELQRIDSHLLFYSC
                     LAMDLGALTAFFYGFRDREKILDIFEETCGGRLIMNYNTIGGVQADLHPNFVKRVKEFI
                     PYMRGIIHEYHDIFTGNIIAQSRMKGVGVLSREDAISFGCTGGTGRASGWACDVRKRMP
                     YGVYDKVDFKEIVYTEGDCFARYLVRMDEIMESLNIIEQLIDNIPEGPYQEKMKPIIRV
                     PEGSYYAAVEGSRGEFGVFLESQGDKTPYRLHYRATGLPLVAAIDTICRGTKIADLIAI
                     GGTIDYVVPDIDR"
     CDS             complement(12391..12993)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q6"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg855_10"
                     /sec_met_domain="Oxidored_q6 (E-value: 1.2e-26, bitscore:
                     83.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEITKKPKIKSIPYDEFIDNESLEKLVKELNAGGANVALGVLDDF
                     INWGRSNSLWPLTFATSCCGIEFMALGAARYDMARFGFEVARASPRQADMIMVCGTITN
                     KMAPVLKRLYDQMPDPKYVVAVGGCAVSGGPFKKSYHVVNGVDKILPVDVYIPGCPPRP
                     EAFYYGMMQLQRKVKIEKFFGGVNRKEKKPDYLRNEE"
     CDS             complement(12984..13334)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg855_11"
                     /sec_met_domain="Oxidored_q4 (E-value: 2.9e-38, bitscore:
                     120.0, seeds: 391, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFTFLVVVLLTALAFVGVVIALSRAISPRSYNLQKFEAYECGIP
                     TRGKSWMQFRVGYYLFAILFLMFDVETAFLFPWAVVMRDMGPQGLISVLFFFIILVLGL
                     AYAWRKGALEWK"
     CDS             complement(13453..13830)
                     /locus_tag="ctg855_12"
                     /transl_table=11
                     /translation="MKQSLKFGLLLVLALLIHCATNGAMEDMCKVSSPTYRQEKCYVSQ
                     DRPIQDALERLYNLYTTQTCDMSHTDVAHVPTDKSMFLLIAYFCDHYKHQSPPYPVSSH
                     SPTYYYDPISYYIYGLRKIVI"
     CDS             complement(13964..14059)
                     /locus_tag="ctg855_13"
                     /transl_table=11
                     /translation="MYFLCVIRKKERKSFFLLHLLTNEDGEITPF"
     CDS             14091..14894
                     /locus_tag="ctg855_14"
                     /transl_table=11
                     /translation="MKRTLWIIFFLLNSLFYLYADSENDSLLKVLDKVISERLIYTQKK
                     EATIKELKKKKVGLNSLEDIYNLNKEIIHQYETFVCDSAEQYIHENIDIAKTIGNKEYL
                     LEEQLRLAFVYSLSGLFIQANDIFKSIKCADLPDHLKALYCWNRIRYYENLIKYTDDVR
                     FSNEYISEKEAYRDTVMSILFDQSDEYRKEKAVKLQDKGSTKEALLILTEIYDKQEPAS
                     HGYAMMAMGLARAYRLIGNYALEEKFLMLAAMTDTKLAVKENEALL"
ORIGIN
        1 ggttagcgga gtccgtattt ttcaatagga ggtatgggag aatttgtaac aaacagattc
       61 tcccatattc tatttattta ttttcgtaat cttcttttag cttttttatt tgctccttta
      121 tggtatcagt gattaccttt tttgtatatt tgtcaaccta ttgtcttaca ataatacaaa
      181 atatgcagac agacaacgag cgatacagaa aaatggcttc tcttgcacaa atcgggtggt
      241 gggaagtaga tttaacggca ggatattatt tatgttccga ttatctttct gatcttttgg
      301 gattggacgg cgacaccatc tctacttcgg attttctgaa cctgatacgt gaagattatc
      361 gcaagcagat tgcccaggag ttccgggcaa attcttctat ccataaggac ttttatgaac
      421 aaactttccc tattcattca aaatatggcg aggtctggtt gcatacccgt ctggcttttc
      481 gtgagaaggg tacaggtgtt gatggaggtg ataagtcttt cggaataatc cagcgcgttg
      541 aggctcccaa ggaagaagat caaagggatg cattaagacg tgtgaatgac ctgctttgtc
      601 gtcagaattt tgtttcgcaa tcgttgcttc gtttcctacg tgatgaggca gtagaatctt
      661 gtatcgcaga tattttaaga gatattctga atctttataa tggaaaaggt cgtgtttata
      721 tttttgaata cgatgaaatt tatgcccatc atagttgtat ctacgaagtt gtttctgaag
      781 gagtatcggc agagatagac aatctgcagg acatgcctgc cagtgagtca aaatggtgga
      841 gtgaacagat attatcgggc aagccgatta ttttaaatac attggagcag ttattagaag
      901 aggctcctga tgaatatcag attcttgtag ttcagggaat caaatcgtta atggtgactc
      961 ctttgatgac aggcgaccgc gtttggggat atatggggat tgatttggtt gagacttacc
     1021 atgactggag taatgaagat tttcaatggt tctcctcatt gggaaatatt ataaatatct
     1081 gtatcgagtt gcgtaaaact aaggacaagg taatccgtga acagactttc ctaaataatc
     1141 tgtttcattt tatgccgatg ggatatatac gtatgtccat tatccgtgac gagaataata
     1201 aaccttgcga ttatcgggtg acggatgcga atgaggtcag ttcaaccttt ttcgggcttc
     1261 ctttggagtc gtatattggt tctttggcat ctgaaaagca tcctgactat ctccaaaaac
     1321 ttaattttct ggaagaaata ctggatagta attcttatag agagaaagat gaatatttcc
     1381 ctcgaacgga acggtatacg cattgggtga tttattctcc cggaaaggac gaaatagtcg
     1441 gtctattcct cgattctacg ggatcggtac aagctaaccg ggcattggat cgtagtgaaa
     1501 aactctttaa gaatatcttt gctaatattc cggcaggagt agagatctac gataaggacg
     1561 gctatttgat agatttgaat aataaggatt tagaaatatt cggtgtagtg aataaatcgg
     1621 atgtgatagg ggttaatttc tttgagaatc cgaatgtgcc gcaggggatt cgtgatcgtg
     1681 tgcggaatga agatctggtg gatttcagac ttaattattc ttttgagcaa gcaggaggat
     1741 attatgagac aagccgttct aatgtgatag aactatattc gaaggttagt aaactatatg
     1801 ataatgaggg caacttcagc ggatatattt taataagcat tgacaatacg gagcgtattg
     1861 atgcaatgaa ccgtattcgt gattttgaga atttcttctt gatgatatcc gattatgcaa
     1921 aagtaggata tgctaaattg aatctcttga accgcaaagg ttatgctata aaacagtggt
     1981 ataagaattt aggtgaggag gaagatattc ctttgagtga ggtggtagca gtttatagcc
     2041 aaatgcatcc cgaagaccgt aagcgtttcc ttgattttta tgatggagtc agagacggaa
     2101 aaaggaggca tttccaaggg gagatgcgta ttcgtcgtcc cggaacgaag aacgaatgga
     2161 attgggtcag cagtaatgta atggtcacca attataaacc ggaagaaaat gaaatagaaa
     2221 tcatcggtat caattatgac attacagaat tgaaggagac tgaagccgaa ttgattcagg
     2281 cacgtgataa agcagagatg atggatcgtt tgaaaagtgc tttccttgcc aatatgagtc
     2341 atgaaatccg tacgccgctg aatgccattg tcggtttctc cgatttgctg gtagaaactg
     2401 aagagctggc agaacgtcag gagtatatta agattgtacg tgagaataat gaacttttgt
     2461 tgcaattaat ttcagatata ctcgatttgt caaagattga agcgggtaca tttgagttta
     2521 ctaacggaga tgtagatgta aatctgttat gtgaggatat tgtccgctct atggggatga
     2581 aagcgaaaga agaggtggaa ctggtgtttg atgatcatct tccggtttgt catgtcatta
     2641 gtgaccgtaa ccgtatacat caggtgatct ctaactttgt taacaatgca atgaagttta
     2701 cctctgaagg aagtattcat gtggggtata aactaaaaga cggagaattg gagttttatg
     2761 tcgaagatac gggaatcggt attgaaaaag agcagttgcc acatatcttt gagcgttttg
     2821 tgaagcttaa ttcttttgta cacggtacag gattgggact ttctatttgt cagagcatcg
     2881 ttgaacaatt aggtgggcgg attggcgttg attctgaaaa aggaaaagga tcaaggtttt
     2941 ggtttactat tcccggagtg atcgtgacgg aagagatgaa ctgtgcccgg tagagtggta
     3001 ataaggcagg tgaatatctt ccttcctcat taataaaagc ggcttttata tagaagaaac
     3061 agtcttggtt ttgatgtcga ttgatactga catgaaacca agaccgtttc tttggtgaaa
     3121 aggtgtagtc cgtttaaatt ccgaacgaca gtttatcgat agattgatat acaatacttg
     3181 caatacccag tccgatgata cccagcgtgc aaagtgccag tccccatttt gtgcagcggt
     3241 cgctgcggaa agtaggaatt gggttgtcgg aaggagtgat atacattgct tttacaatca
     3301 atagatagta atacaacgaa atcactgtat ttaccaatgc gatgaatacc agcaagtgga
     3361 aacctgcatc gaaagcagcc atgaagataa agaacttaga gaagaatccg gcaaacggag
     3421 ggatgcctgc caatgagaac agagacagag tcatcaagag agcgattttg ggattcgttt
     3481 tataaagtcc tgcgtaatct tcgagcgtga atttctgact gcgtaatgcc acgatagtga
     3541 taacggcaaa tactccgagg ttggcggcag cgtacactaa tacataatat accaatgccg
     3601 tcatgccttg tgctgtgcct ccgataacgc ctaacataat atatcccgct tgcgaaatac
     3661 tggagaacgc catcaaacgt ttcaggtttt gctgacggac agcaaatata ttggcaatag
     3721 tgatagaagc gatggttacc caataaagta cttcctgcca gtcattaatc attggagcga
     3781 atactttgat aaggatggcc aataatacaa atgctgccga tccttttgat ataacactca
     3841 aataagcggt aactgtactc ggagcgcctt cgtaaacgtc tgctgtccat aagtggaatg
     3901 gaaccagtga taacttgaat gccattcctg tgaagaagaa tataaatgcc atgatctgta
     3961 acggatttcc gtcgatatgg gcagggaggt catcgaaata aagagtcccg gcagaaccat
     4021 agatcatgga cagaccaaac aacagcaatg cactggagaa aagagctgtc agaatgtatt
     4081 tggcacctgc ttcggcagag ttgtgacggt atttatcgaa ggcaatcaat gctgccatcg
     4141 gaatagaagc tgtttcaaga ccgatgaaga acatcaggaa atgtccggcg gaaatcatga
     4201 gatacatacc aaacaaggta gagagtgtaa gcacatagaa ttctccttgt ttgaatgaag
     4261 tgtcttctct tttcatccac tcgtgcgcca tcaggaaaac aatcagtgta ccgacattca
     4321 ggatcgattt aacaacagtg tgcatcggta catagtgata cataccaccg aatgcatcgg
     4381 cagcagttcc cggaatcaag ttgatagccg tatggatagc catcagaata acgggcaaca
     4441 tggtgttcag gcgtgctttc ccactatttt tgtgtgcatc cggactcatg aagaggtcag
     4501 ctagaaatag cagcagtaag acagctatga gcgacagctc ttctcgcata tttagaaatt
     4561 gtgaataatc catcttgttt atttatgaat taagaattat gatttatgag ttaggggatt
     4621 agttgtgaga caaccggtaa tacgctttca ccaatcatgt ggctaaccca gaaaggagcc
     4681 atacctagtc cggcaacgca aacgatgagg cagataacgg ctacacgttc gtcccaagtt
     4741 gcgtcggtca gttcgaggtg atgtttgttg gtgcaggttc cgtatagaat cttacctacc
     4801 aggcgcagga tgtagactgc ggtaatcaca atcgaagagc aggcgatgat ggtcagtgtg
     4861 cggtgaaata cgtcgttgtt ctggaaagag ccgacgaaga tggtcatttc agcaatgaaa
     4921 ccgcttaatc ccggcagacc gaggttggca agaccggcaa tcacataaca tacactaagg
     4981 aacggcataa ttttcattaa accggcaagt tcgcgaacgt cacgtgtgtg tgtacgtcca
     5041 tatatcatac cgatcagagc aaagaacaag gctgtcatca atccgtgtga aagcatttga
     5101 aggattgctc ctgttgctgc tgtctggttt agcatcagaa tggcgaaaag aaccagtccg
     5161 cagtgagata cggatgaata agcattgata tatttcaagt cggtctgtac gcaagcggag
     5221 aaggctccgt agactacaga gatacctgtc agtatcagga atatccagga aagttcgttg
     5281 gctgcttccg gcatcagata catggcgata cggaaacatc cgtaacctcc cagtttcatc
     5341 aatactccgg catgaagcat ggatacggca gtcggggcag aagcgtgacc gtcaggactc
     5401 catgtgtgga acgggaaaag ggcgcccaat acaccgaagc cgaggaaagt cagcgggaac
     5461 cagatgcatt gctgtgcaaa aggtatgttg tgcaactgtg caatttcgag aaggttcatg
     5521 gtggttgctc ccgagccgaa atagattccg agaataccga tcaataggaa agcggaaccg
     5581 cccatcaaca taagggtcag tttcatggct gcatattctt tacgtcctga tccccataca
     5641 ccaatcagca ggtacatcgg tatcaacgca atttcataga acatgaacat ggtgaacaaa
     5701 tcgacggata taaagaatcc gaatactccc atagacaaca gggtgaacca gaggaaatat
     5761 tctttcgtca gcggttgcag gcgccaggaa gcgaatgtac cggtgaatac gatgacagca
     5821 gacaataaca acatggctac cgaaattccg tcaacaccta ctgaataaga tatgtgaagc
     5881 ggggcatacc aaagcgtatc tgcacggaaa agcatttctg ccgtatttcc ggcgctacgc
     5941 tctcccagat acaggaatgt aagtacgacg gaggcaatca gaagtgccga tgcgccagta
     6001 accataaccc cccggatggc tttgattcct cgtgctgccc aaagtccggc cagcatcaat
     6061 aaggggataa gtacgaatat ggataagaaa ttcatcttta tgatttacta tttaaagatt
     6121 tactatttac tatttagaga atcagcagta ggataagtgc caatgcaccg caaaggaaca
     6181 catacgcata ttgttgtacc tgaccgctct gcaaaccacg aatctcgtcg cttgttgtat
     6241 tggtggccca tgccaggaag tcaaagaatc catccactac atgacggtcg aaccatgcga
     6301 taggagtaga gatgcagcgg aagataatct tatgcgtaat aaactggtag atatcatcaa
     6361 tatagaagcg attataggct gccttgtgca gacctttgaa tcgttttgcc aacgaatcag
     6421 caacaggctg tttggcattc ttgtacatcc atgtagcgat tgcaatcgaa ataatcgcaa
     6481 taacaacgct cgtaatagct actgacggat cgagatggat agaataagat tcaccattcg
     6541 aactgatgaa gtgtccgaaa ggaataaatc ctgctccaca agttacaact gccaggaaca
     6601 tcagcgggaa agtcatagcc aacggactct catgtgggcg gcaaggtgcc gcttccaagt
     6661 ttccgtgcgg cgtgttatgt tccgaatggg aacctgcccg gggcggctcg ctcccccaaa
     6721 aaataccgta gtaaaggcgg aacatataga aagctgtcat tgcagcgatg actgtcatca
     6781 cccatcccat tacagggctg tattggaaac aagcagccag aatttcatct ttcgagaaga
     6841 agcccgagaa cggaggaata ccggcaatag ccagacaagc aatcaggaag gtccagtgag
     6901 tgatcggcat atatttgcgt aaacctccca tagcggacat ttcattagaa tgtacggcat
     6961 gaataatgct acctgcaccg aggaagagta atgccttaaa catggcatgt gtgaaaaggt
     7021 ggaacatgga agccatgtag cccaaacctc cttcgtgcgg attcatggaa gtacaaacac
     7081 ccagagctac catcatgaag ccaatctgtg aaatggtaga gaaagccagt acacgtttga
     7141 tgtctgattg tacgcaagcc acacttgccg cgtagaatgc tgtaaatgca cctacccaag
     7201 caaccatgtg cagcgtattc ggtgcgtatg taatgaaaag tgggaacata cgtgccacca
     7261 gatatacacc ggcaactacc atggtagccg catgaatcaa tgcgctgacc ggagtaggac
     7321 cttccattgc atccggcaac cagatatgca acgggaacat ggcactttta ccggcaccac
     7381 cgacaaacat cagtccgaga gccaacggaa gcatagaagc tccaccgctt atcaaggata
     7441 ctgtatccgg agtgaagccg aatgtaccac cgtaatatcc gtaaatcagg ataccgatca
     7501 ggaagcccaa gtcagcaaag cgagtaacaa taaacgcttt cttggaagca gcaatggcag
     7561 ccggttttgt ataataaaaa ccgattagca ggtaagaact tacccccacc agctcccaaa
     7621 aaaggtacat ctggaagatg ttggttgcaa cgaccaatcc cagcatagac atggtaaaca
     7681 gggataggaa agcgtaatag cgttgaaaac cgacttctcc tttcatgtaa ccgaaagagt
     7741 agatatgtac catcagtgac actgtagaga tgacgatcaa catcattacc gatataggat
     7801 cgagcaagat gcccaaatcg aagtgtaaag tctctgtaaa aggaagccac gtgaagttgt
     7861 aaggcatcag tgtggcgaat gttccgtctt ccagtggtgg agcggagaaa tattggatag
     7921 ctgtaacgta ggatagtact gctactgctc ccagtatcag cgtaccgatt gtacccgctg
     7981 tccggtggga catccactta cctccgattc ccaatatgag aaaggagaag aaaggaagaa
     8041 ggagtattag aattgttagt tccatacagt tttatttaat tacttgagtt attattatta
     8101 attcttggtc ttatagctga taatcactat actcggacct tctgttttgt ttcccggtgt
     8161 gaaactagtt gttcctcggt gagaaacact ttgtttctcg gtgtgaaacg aagtgtttca
     8221 agggatgaaa caccttgttc ctgggaatga aacaaatcac cacttcaact cgtccaggtt
     8281 gcgcacctga atgcttcgaa gattacgata aatgttaatc atgatggcga tagctattgc
     8341 agtttccgca gccgagatgg cgatggaaaa gagtgcaaag aaataaccct ccattccccc
     8401 cggaaaaagg aaacgattga atacggcgaa gttgatgtcc gtagcattca gcattaactc
     8461 tacagaaatc aggatagcca gtgtatttcg gcgggtaaag aatccataga ttcctgcaaa
     8521 catcatgatg gtagaaacta ccaggtaata ttccatgtgt atcatattcg aactctattt
     8581 tgatagttaa tacttaaaat tcctatctct tacgtgcaat catgatgcca ccgatgatac
     8641 acgccagcaa taatatgctg acagcttcga aaggcaatac ataaccgtat ttgtcactac
     8701 ttaataaagc gttcccgata gcatgaatgc taatttcttg cggggccaaa ttagctgtct
     8761 gcatgaaatc gtgcttcagt gtgataaaca ggataatggc caaaccggca atcatagtga
     8821 agagtccggc taagacttta cttcgttttg ctttctcggc ccggtcgcct tctccactgg
     8881 tcaataggat ggagaataca taaagaacga cgataccacc ggcataaacc ataatctgaa
     8941 cggaacccag aaaggtgtaa cccagcaaaa aatagatgcc ggccgtgccg aagagcacga
     9001 agagcaggta ggtggccgag cgtacgatac gttgggtagt caccgtcatg atggacatag
     9061 caataataaa tgctgccaaa aagtagaata ctactgtttc aagtgttgat cccatatcta
     9121 aacttctttt ttcttttcta ttactttact accgtcgtgg ttcaacttca ggacaagttt
     9181 cgtccggtcg aagactgcat gttcgaagtt ctggtcgaac gtgatggcat cgtgcggaca
     9241 agcattgaca cagagctggc agaacataca ggcacccaaa tcatattcat aggttgccag
     9301 aattttcttc ttctttccat cttctgtttc gacggtttcg ctggtcactt tgattgtatc
     9361 gttcggacag gccatttgac acaatccgca agctacacag cgatgttcat tattctcatt
     9421 gtggggcata ttcagcgtac cacgaaaacg gtcgaacatt ttcagctctt tccggttttc
     9481 gggatattgc tcggtcactt tcttacggaa gtataccttg atgctggttt tcatacccgt
     9541 tgccagtgta ctgatgccat gcaccagacc acctaagtac gtatattttt tatctttata
     9601 ttccataatt ttcatttatc aaaagtggaa gccgaaagct acgcagcatg ccattaataa
     9661 tagatttacc atagaaattg gaaccaggta tttccattcc agattcaaga tctggtcgat
     9721 acgcaagcgt gggaaagtcc atttgatcca catcagaagg aataccacaa agaatgcttt
     9781 ggcgaagaac cagataaagc ccggaatata atccattaca gtgttaaatc catccaaacc
     9841 aacaatgtgc agcggcatcc atcctcccag gaagatagtg gcggcaacac tggctacgat
     9901 aaacagattc aagtattctg ccagatagaa gaaaccgaaa cccataccgg agtattcagt
     9961 atgatatccg gctgtcagct cactttccgc ttcgggaagg tcgaacgggc cacggttaca
    10021 ttctgcattt ccggcaatca gatagatgat gaaagcaatg accgcaggaa tatgtccctt
    10081 gaagatgaac caaccattag cttgtccttc tacgatttca gaaaattgca tggttcccgt
    10141 cagcactacc attgtcatga tactcatacc aacagaaagt tcataactga taatctgtgc
    10201 accgcttcgc atggcaccga tcaaagagaa tttgttgtta ctaccccaac cggccagcaa
    10261 gataccgaca actccaatgc tggaagctgc caacaggaag aacacgccca cattaaagtc
    10321 cagaatcgcc gcacctttat taaaaggaat acaagcgaaa gtcaggaatg aagcgataat
    10381 caccatgaat ggagcaagat tgtaaaggaa atggtcggca cccttcggca tgaagatttc
    10441 tttggtcagc attttgagca cgtcgcagac cacttggata gaaccccatt taccaacacg
    10501 gttcggtcca agacgacact ggaagaaacc gcagacctta cgctccatgt agatcaatat
    10561 gatagccagg atggcataca gtgctacgag gcacacgccg acagctacac attctataaa
    10621 gatggctaat ccctccggca taatggagag cagtagctca tgtatccagt ttgttactat
    10681 actaaagtcg aacatatatt tttaataatt aagtattatc tgtcaatatc cggaacgaca
    10741 taatctattg ttccgccaat agcaattaag tctgcaatct ttgttccccg gcaaatggtg
    10801 tcaattgcag caacaagcgg caatcccgta gcacggtagt gcaggcggta aggcgttttg
    10861 tcaccctgac tttccaggaa gacaccaaat tcaccacgac ttccttctac tgctgcatag
    10921 taactgcctt ccggaacacg gatgataggt ttcatcttct cctgataagg tccctcggga
    10981 atattgtcta ttaattgctc aatgatgttc agactttcca tgatctcatc catacgcacc
    11041 aggtaacggg caaagcagtc accttccgta taaacgattt ctttgaaatc gactttgtca
    11101 tatacaccgt atggcattcg tttacgtacg tcacacgccc atcctgatgc acggcctgta
    11161 cctccggtac aaccgaaaga gatggcatct tcacggctta acacaccgac gcctttcata
    11221 cggctctgtg cgatgatgtt acccgtgaat atatcgtgat attcgtggat aattcctctc
    11281 atatatggaa tgaactcttt tactcgtttg acgaagttag gatgaagatc agcctgtaca
    11341 ccgccaatcg tattgtagtt cataatcaga cgtccgccgc aagtttcttc aaagatatcg
    11401 agaattttct cgcggtcacg gaatccataa aagaatgctg tcaacgctcc taagtccata
    11461 gcaagacaag agtagaacag caagtgagaa tcgatacgtt gcaactcgtc cattatggta
    11521 cggatgtact gtacgcgttc actgacctca atgcccatgg ctttttcaat gcacatacac
    11581 aatgcatggc ggttctgatg cgcgcccaaa tagtccagac ggtctgtcaa agccaatgtt
    11641 tgagggtaag tgaggctttc attcattttc tcgatgcctc ggtggatata cccgcagttc
    11701 gcatcaatct tacgaataat ttcaccttcc agagaaacac ggaagcgcat tacaccatgg
    11761 gtagcagggt gttgcggacc gatgttgact acatattctt cttcgccgaa cagtttcgtc
    11821 tctttgttct tgatggttcc gtccgggttc agttctattt cttgagtcgt atcaaacgtc
    11881 ttttcattgg tcatgcacag tgggttatcc ttttccggat cgttatcttt acgcatcgga
    11941 taaccgatcc aatcgttgcg caggtagagc cggcgcatat caggatgacc gacaaaggtg
    12001 atgccataaa aatcaaaaac ttcacgttcg tagaagtcgg ctatcttcca gatgtcgctg
    12061 acagacggaa tttccggtag ctcgcggttg gttgtcgctg tttttagtgc tatccgttcg
    12121 cctgtaatgg tagattccag atggtagact acgcctaagc cgcggagttt ttccggagcg
    12181 tctttctcat cggctactcc ccagtccata ccggtgaggc tttcgagaaa gtccatctgt
    12241 ttttcatttc gcaagcgcag catctcgtcg tgtaacgctg caggagctat aaattgtatt
    12301 tcttgcataa atcaaattaa attaagaatg aaaaattaag aatgaaaaat ctgccgggat
    12361 gttgcatgcg aattcttcat tcatcattca tcattcttca tttcttaaat aatccggttt
    12421 cttctctttt ctgtttactc caccaaagaa cttttctatt ttcactttgc gttgcaattg
    12481 catcatgcca taatagaatg cttcaggacg tggcgggcat ccgggaatat atacatctac
    12541 cggaagaatc ttgtccaccc cgtttactac gtgataggac ttcttgaaag gacctccgct
    12601 gacagcgcat ccgcctacgg caaccacata cttcggatcg ggcatctggt cgtaaagtcg
    12661 tttcagtacc ggagccattt tattggtgat tgttccgcat accataatca tatcagcctg
    12721 acgcgggctg gcacgtgcta cctcaaaccc aaagcgggcc atgtcataac gcgcggcacc
    12781 cagtgccata aattcgatac cacaacaact ggttgcaaag gtaagcggcc acagtgaatt
    12841 gctgcgtccc cagttgataa agtcgtcaag tactccgagg gcaacattgg ctcctcctgc
    12901 attaagttct ttgaccaact tttccaatga ttcattgtcg ataaactcat catacggaat
    12961 agattttatt tttggctttt tggttatttc cattccaaag ctcctttcct ccaggcataa
    13021 gcaagaccca gaactaaaat gataaagaag aagagaacac taataagtcc ctgtggtccc
    13081 atgtcacgca taactaccgc ccacggaaac agaaaagctg tttcgacatc gaacataagg
    13141 aataggatgg caaacaagta gtagcctaca cggaactgca tccatgattt accacgtgtc
    13201 ggtataccac attcataagc ctcaaacttt tgcaggttgt atgaacgggg agagatagca
    13261 cgcgagaggg ctattactac accgacaaaa gcaagcgctg tcagtaaaac aacaactaaa
    13321 aatgtaaaat tcataattca atagctgttt agattgaata ttatatagaa ataagcaatt
    13381 agtctattcg ccctatggag aataaaacca actgtaataa atgacgagca aaagagtcta
    13441 ctgtactgta ggctaaatga caatctttct caacccatat atataatagg agataggatc
    13501 gtaatagtat gtaggagaat gggatgagac agggtaaggt ggactttgat gtttgtaatg
    13561 gtcacagaaa taagcgatta acaaaaacat gcttttatct gtcggaacat gtgcgacgtc
    13621 tgtatgactc atatcacagg tttgagtcgt ataaagatta taaagacgtt ccaaagcatc
    13681 ctgaatcgga cgatcttgtg atacatagca tttctcctgc cgataagtcg gggaggaaac
    13741 tttgcacata tcttccattg ctccgttagt tgcgcaatgg atgagcaaag ccaacactaa
    13801 aagtagtccg aattttaagc tttgtttcat ctttctcctt taacggctgc aaatatagaa
    13861 ctaatattta tactttttgc aaagtccgta tggcaaaaaa gcttttttta actccatatc
    13921 ttttagattc attttttagt cagcatggtt tcacaaatat catttagaat ggggtaattt
    13981 ctccatcttc atttgttaaa agatgcaata aaaagaatga tttacgctct tttttgcgaa
    14041 ttacacaaag aaaatacatt tttttgcaga ttaagaaaga atacatgatt atgaaacgca
    14101 cactatggat tatatttttc cttctaaact ccttgtttta cctctatgca gatagtgaga
    14161 atgattcttt gttgaaggtg ttagacaaag tgatttctga acgtttgata tatacccaga
    14221 aaaaagaagc taccataaaa gaattaaaga aaaagaaggt tggccttaat tcgttggagg
    14281 atatatataa tttaaataaa gagattatcc atcaatatga gacttttgtc tgtgactcgg
    14341 cagaacaata cattcatgaa aatattgata tagcaaaaac gatcggtaat aaagaatatc
    14401 ttttggaaga gcagctccgg ttggcttttg tctattcctt atccggtttg tttattcaag
    14461 caaatgatat ttttaagtcg ataaaatgtg cggatttacc cgatcatttg aaagctttgt
    14521 attgctggaa tcgtatacgt tattatgaaa atctcattaa atacacggac gatgtacggt
    14581 tttcaaacga gtatatatcg gaaaaagagg cttatcggga tactgtgatg agcatcttat
    14641 ttgaccagtc ggatgaatat agaaaagaaa aagctgtgaa gcttcaagat aagggaagta
    14701 ccaaagaggc tcttctgatt ttgacagaga tatatgataa acaagagccg gcatctcatg
    14761 gatatgctat gatggctatg gggcttgcca gggcttatcg gttgattggg aattatgcac
    14821 tggaagaaaa gtttctaatg ctggctgcta tgacagatac aaaactggct gtcaaagaga
    14881 atgaggcatt attg
//
