LOCUS       c00954_gnlPro..        15645 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GBCKGDED_954.
ACCESSION   c00954_gnlPro..
VERSION     c00954_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 03:28:07
            Original ID  :: gnl|Prokka|GBCKGDED_954
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15645
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15645
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8926:14144]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      8927..14144
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15645
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15645
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             557..706
                     /locus_tag="ctg954_1"
                     /transl_table=11
                     /translation="MGIRVSCMGKQNNNLSDRGLYTNGKYNESFVLIFILNIEVNTLKQ
                     YGIS"
     CDS             693..1691
                     /locus_tag="ctg954_2"
                     /transl_table=11
                     /translation="MELVSTYGIIFVILLALELCYFKVADHFNIIDKPNERSSHSTIVL
                     RGGGIIFLIGVWIWSVFFGFQYPWFLVGLTLVAGISFVDDIHSLPDSVRLVAQFVAAAM
                     AFYQLGILHWSMWWVILLALIVYVGATNVINFMDGINGITAGYSLAVLIPLALVNMDDI
                     FVEQSLIISTILSSLVFCIFNFRPKGKAKCFAGDVGSIGIAFIILFLLGNVIIKTMDIT
                     WLIFLLVYGVDGCLTIVHRIMLHENLGEAHRKHAYQIMANELKVGHVKVALLYTVMQLV
                     ISLGFIYLCPDTVLAHWLYLVGVSAVLAIAYILFMKKYYHLHEEYLISLKQ"
     CDS             1697..2134
                     /locus_tag="ctg954_3"
                     /transl_table=11
                     /translation="MEFDKEFLDKLFEQAKENPRLRQNFDLRTSSADTSQRMLNALLPE
                     TKVPIHRHEDTTETVICLCGKLDEVIYEEVVSYEKDTDDFQKGVNVQDVARKVEYREVQ
                     RIHLNPTETKYGCQIPKGAWHTVEVIEPSVIFEAKDGAYAR"
     CDS             complement(2419..2847)
                     /locus_tag="ctg954_4"
                     /transl_table=11
                     /translation="MRTITLIIIHCSATPEGKSLSAEACRQDHILHRGFRDIGYHFYIT
                     RDGEIHRERALEKVGAHCRNHNAHSVGVCYEGGLDANGKPKDTRTLEQKGALLALLREL
                     KRQFPKALIVGHRDLNPMKGCPCFDAVKEYSQVISYQK"
     CDS             complement(2852..2959)
                     /locus_tag="ctg954_5"
                     /transl_table=11
                     /translation="MSKSSSSRSVWSLVLKIVITVATAIGGVFGIQSCM"
     CDS             complement(3136..3624)
                     /locus_tag="ctg954_6"
                     /transl_table=11
                     /translation="MIRYKIYQNQQKKGLNAGKWFARAVSDETFDLAKLAEHMSKHNSP
                     YSGGVIKGVLSDMVDCIKELLLDGKCVKIDDLAIFGVGIRSKAADTLEEFSLEKNISGM
                     RLKARATGNLSTNNLKLDSQLKQQAEYQKPTTAGGGSDSGDNPDPKPDGGGEAPDPAA"
     CDS             3844..4062
                     /locus_tag="ctg954_7"
                     /transl_table=11
                     /translation="MSEFKIRAYGRMELAQLYSPQLTDIAAYRKMKKWISLCPGLLQRL
                     YDLGYESKRRSFTPLEVRVIVDALGEP"
     CDS             complement(4244..6085)
                     /locus_tag="ctg954_8"
                     /transl_table=11
                     /translation="MTDIESLRRLTEAVEAAGADIAPTYLEYVQLSFAIATDCGEAGRD
                     FFHRLCRVSPKYQREHAERVFSNALHTQRGEVHLGTAFHLAEATGVSICIEEMPKHPTG
                     TKGTAGTARKFPPHTGAYNKVGNDNISEEREGEEELLPGSEPQHQLPTFPKNDWPEFLQ
                     RIIKAGSSPIQHDIMLLGALTALGACMSRHVRCLYGGKYHHPSLQCFVVAPSASGKGIL
                     SYIRLLVEPIHDEIRKEVTIQMKAYKKEKAEYDAMGKERTKKEAPQMPPNRMFLISGNN
                     TGTGILQNIMDSDGTGLICEAEADTLSTAIGSDHGHWSDTLRKAFDHDRLSYNRRTDQE
                     YREVKKSYLSVLISGTPSQVQTFIPTAEDGSYSRQLYYYMCGISKWISQFMDNEIDWEE
                     IFTAMGLEWKEKLSVIKAHGIHTLQLTDEQKEEIDTVFSNLFERSSVANGREMYSFVAR
                     LAVNLCRIMSEVAVLRALESPQPYDFKTSPTSPFTPDKEIPADNRKDDIITRWDVSISQ
                     EDFHAVLSLAEPLYCHATHILSFLPNTEISHRPNADRDYLFQKLGDEFTRTQLLEEAVA
                     MGIKENTALTWLKRLTKRGILVSIDGKGLYARACVYE"
     CDS             complement(6113..6742)
                     /locus_tag="ctg954_9"
                     /transl_table=11
                     /translation="MPNNYRMSYFMPPIAPIKDKQGRLMTPPTLIPFCEVSIEQVFQMI
                     TCNENLKALTEQVRNSEDIRTAKASLLPYVTPCGTFTRRSSKDFVSPSHLVIVDVDGLH
                     SYQEAVEMRRMLYDDPLLQPVLTFVSPSGLGVKAFVPCHYSSTTNDIPNITDNMSWAMR
                     YVETAYNTVTAVSSETKSKVDFSGKDLVRSCFLSYDPEALFRTTNE"
     CDS             6910..7062
                     /locus_tag="ctg954_10"
                     /transl_table=11
                     /translation="MENEKGLYVALGVYIGELQKRADLKNDEIRKSVHIGHSTFNDLKK
                     GQNAH"
     CDS             7342..8211
                     /locus_tag="ctg954_11"
                     /transl_table=11
                     /translation="MSSKIYPIGIQNFEKIRKDGYFYIDKTALIYQMVKTGSYYFLSRP
                     RRFGKSLLISTLEAYFLGKKELFEGLAMEKLEKDWTTYPIFHIDLNTEKYDTRESLDSI
                     LNFTLEKWEQQYGTAPSETTFALRFRGLIERAYEQTGQRVVILIDEYDKPMLQAMGNEE
                     LQKEFRNTMKAFYSVLKTMDGCIQFAFLTGVTKFGKVSVFSDLNNLDDISMRKQYVDLC
                     GVSEKELHDNLEIELHELADAKELTYGELCNRLREYYDGYHFTYNSIIKFLLPFYANTN
                     AVESEFEI"
     CDS             8354..8497
                     /locus_tag="ctg954_12"
                     /transl_table=11
                     /translation="MVAISFPCAITKTQKITIYYVEKVGGMLRSSQIMIKFAAICNAEF
                     AK"
     CDS             8494..8919
                     /locus_tag="ctg954_13"
                     /transl_table=11
                     /translation="MTNNTIKHLGIVENIQGSHLSVRIVQTSACAACSAKGHCSSADSK
                     DKIIDIIDTAASSYQVGEKVMVVGETSMGMMAVVLAFVLPFVLLIFSLFLLMAWIENEL
                     YAALLSLAVLIPYYFVLWLNKTRLKQQFSFTIKPINN"
     CDS             8927..9841
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.9; E-value:
                     3.3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg954_14"
                     /sec_met_domain="Fer4_7 (E-value: 1.1e-12, bitscore: 38.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.8e-09, bitscore: 26.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 9.9e-09, bitscore: 25.6,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.7e-08, bitscore: 25.5,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 4.2e-11, bitscore: 32.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.5e-06, bitscore: 17.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAAGEAEPMVAVV
                     RCNGTCANRPRTNQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPNKCKSCRKCVEVCPQNSIIELNFPPRKPKEEAPA
                     APKPATKVETPAAKATEAPKVTE"
     CDS             9866..11203
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg954_15"
                     /sec_met_domain="Fer4_10 (E-value: 2.1e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.2e-16, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 3.6e-51, bitscore:
                     163.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.4e-29, bitscore: 92.6,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.2e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PVVAKGDVVKVGTRIAEPAGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEETIDRSTTLVKECELSAEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNQKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             11209..12216
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg954_16"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.8e-120,
                     bitscore: 392.1, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIHAADKSAAMDALNQIPDALSLLIGQNGGCLGEVSALALLIGLVYMLWKKIIT
                     WHIPVSILATVFIFAGIMHLADPEKYVSPILQLLSGGLMLGAVFMATDYVTSPMSKKGM
                     LIYGVCIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             12243..12950
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg954_17"
                     /sec_met_domain="FMN_bind (E-value: 2.6e-23, bitscore:
                     73.0, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAVSVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     FTNNPVAESDTIFSEKDGKKNVDFIVYPAKNGEELVGTAVEAKSMGFGGELKVLVGFNA
                     EGKIYNYSLLAHAETPGLGSKADKWFGAYDPAKGEQAVSHEESKKSILGMNPGEAPLTV
                     SKDGGAVDAITASTITSRAFLNAVNAAYQAYKAEGGKVNGVSGASQKATGADSDTATGA
                     TIKVELTDSVSAK"
     CDS             12965..13549
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg954_18"
                     /sec_met_domain="Rnf-Nqr (E-value: 7.9e-71, bitscore:
                     228.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVMMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNAVASMFDGIGMGLGFTIALTLLGAVREFLGTGKIFDLTIMP
                     EEYGMLVFVLAPGAFIALGYLIALINSFKKA"
     CDS             13572..14144
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg954_19"
                     /sec_met_domain="Rnf-Nqr (E-value: 1e-62, bitscore: 201.7,
                     seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPLLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDVFGLGYLQTITFILVIAGLVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQMSLVKVP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             14368..15402
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg954_20"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 3.7e-52, bitscore:
                     168.1, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPVFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTVASGAPINAIMLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEKKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             15449..15538
                     /locus_tag="ctg954_21"
                     /transl_table=11
                     /translation="MRFVYLMLIDLKLFMSMRIYVNSTYASPA"
ORIGIN
        1 atgatattcc ccctttccta aaaaatgtat tagaaatttg tcggtattac attgaaaaaa
       61 aacatcttga ttgtataaaa ttgcctgtta aggaaaatac ggttgaatgg atgtggaaat
      121 gtttttagaa gagtaatgaa acgtctattc aacaaagtat agaagttaca ataaatcaaa
      181 atcaatatat ttttgaagag tgaagggtaa aaggtgagag gtatgattac acgaatgtgt
      241 aacgtgagaa ttttattcta tgttgttaat gataaagaat cataaattaa tttggataaa
      301 caaggaaaaa tgtttaccgc tgtttctaaa cacctgtttc atcaaatgta tgtttgtaat
      361 gatagctgtc aagaatattg ttcataggct ctgctcatag gacgagacgt tgccaatagc
      421 atttcagaga gtattcttgg atcgtatgat caaaggttga tattgggata tcgaaacttg
      481 gagctggcgt tgaaaatttt aaactacagt agcaatctta gtttattact ttctaataaa
      541 atagcattga aaaaagatgg gaatacgagt gtcgtgcatg ggaaaacaga acaacaactt
      601 atcagacaga ggattataca caaatgggaa atataatgaa agctttgtgt tgatttttat
      661 attaaatatc gaagtaaata cattaaaaca atatggaatt agttagtact tatggaatta
      721 tttttgtgat tctattggca ttagagttat gctatttcaa ggtggctgac cactttaata
      781 ttatcgacaa acccaacgaa cgctcatcac actctacgat tgtattgcgt ggcggaggta
      841 taatcttctt gattggtgta tggatttgga gtgtattctt tggatttcaa tatccctggt
      901 ttctggtagg cctgacgctt gtagcaggca ttagctttgt agatgacatc cattcattac
      961 cggactctgt aagattggtc gctcaatttg tagctgccgc aatggcattc tatcagcttg
     1021 gcatattgca ttggtcaatg tggtgggtaa tactgttagc actaatagtc tatgttggtg
     1081 ccacaaatgt aataaacttc atggatggaa tcaatggtat cacagcaggc tactctttgg
     1141 ctgtattgat tccgttggct ctggtgaata tggatgatat ttttgtagaa cagagtctga
     1201 tcatatcaac gattctttct tcattggtgt tttgtatttt caatttccgt ccgaagggta
     1261 aagcgaaatg ctttgcaggg gatgtcggct ctatcggcat tgcttttatc atactgtttc
     1321 tgttaggtaa tgtaataatc aagacaatgg atattacttg gctgatattt ctgttggtat
     1381 atggtgtgga tggctgtctg actattgtac atcgtattat gttgcacgaa aatttgggcg
     1441 aggcacatcg taagcatgct tatcagatta tggctaatga gttaaaagta ggtcatgtaa
     1501 aagttgcatt gctgtatacg gttatgcagt tagtgatttc ccttggattt atctatctct
     1561 gtcccgatac agtgcttgct cattggttat atctggtggg tgtatcagct gtattagcta
     1621 ttgcttacat attattcatg aaaaaatact atcatttaca tgaagaatat cttatatcat
     1681 tgaaacaata acgattatgg aatttgataa agaattttta gataagttat ttgagcaagc
     1741 taaagagaat ccacgtttac gtcagaactt cgacctacgc acttcatctg ccgataccag
     1801 tcaacgtatg ctaaacgcat tgttgccaga aactaaggtg cctatccatc gacatgaaga
     1861 tactaccgaa acagtaatct gcctgtgtgg taagttggac gaagtaattt atgaggaagt
     1921 agtttcgtat gagaaggata cggatgattt tcagaagggg gtgaatgtac aagatgtagc
     1981 tcgtaaggtt gagtatcgag aagtacagcg tatccatctc aatcctacag aaaccaagta
     2041 tggttgtcag atacctaagg gtgcatggca tactgtggaa gtgattgaac catctgtcat
     2101 ctttgaggct aaagatggag cttatgctcg ttaaacgatg aaaaacagat gaaatgaata
     2161 ggaagtactg aaagtgcttt ttaatacgtt atgttataat tgaatattta caatgagatg
     2221 gaaaaatgta ggtccctaga ttcatgtgac aaacatgaat ccctacattt agtagattag
     2281 gagcaatata gtggtattgt tctaatctcg ctcttcatat tagtgttaac actaatatga
     2341 tttccaaaaa ataccaactg tctgtgaaga tcgttgatat ttttttatac aataagccgt
     2401 gtggaaatct aaaagaagct acttttgata agaaattact tgggaatact ctttcaccgc
     2461 atcaaagcac ggacatcctt tcattggatt caagtcccgg tgtcccacaa tcaacgcttt
     2521 cggaaactgc cttttcaact ccctcaacaa agcaagcaaa gctccttttt gttccagtgt
     2581 acgcgtatct ttcggttttc cgttcgcatc cagtcctccc tcataacaaa caccaaccga
     2641 atgggcatta tgattacggc agtgtgcccc gaccttttct aacgcacgtt cccggtgaat
     2701 ctccccatca cgagtgatgt aaaaatgata gccaatatca cggaaaccac ggtgcaagat
     2761 atgatcctgt cggcaagcct ccgccgaaag ggactttcct tccggcgtgg cactgcaatg
     2821 aatgataatt aatgtaatag tccgcatggg gttacatgca actttgtatt ccgaacacac
     2881 ctccgatggc ggtggctaca gtgataacga ttttgagaac taagctccat acagagcggg
     2941 aagatgatga tttactcata caataacagg ttttaaataa attaataata gttttctttt
     3001 accacagatt tactgtaggt ttgccatagg tttaccacag atctacacag actcacacag
     3061 ataaataatc gactacttta gcaactacca attcaatata atctgtggaa atctgtgtag
     3121 tctgtggtga atcttttagg cagccgggtc aggcgcttcg ccacctccat ccggtttcgg
     3181 atcagggttg tcacccgaat cagaacctcc tccggcagtt gtcggtttct gatattccgc
     3241 ctgctgcttc aactggctat cgagtttcag attattggtc gacagattac cggtggcacg
     3301 ggctttcaga cgcatgccgc taatattctt ctccaacgag aactcttcca gcgtatcggc
     3361 tgccttactg cgaataccca caccaaaaat ggcaagatca tcaattttca cacacttgcc
     3421 gtctagcaac aattctttga tgcaatctac catatccgaa agcacacctt tgatgacacc
     3481 accggaatac ggtgaattgt gcttcgacat atgttcggca agctttgcca aatcaaacgt
     3541 ctcgtcgctt actgcacggg cgaaccactt acccgcattc aagcctttct tctgctggtt
     3601 ctgataaatt ttgtaacgaa tcataaaaca ataaattaaa gggttaaaca tattgtccgg
     3661 ggattctttt ccctttcgac gatacaaaaa tactactccg gatctcccgg aaatcagctg
     3721 tgcacggttg tgtctggtag cggtcggtta tttgtcatta tagtcggtta ttcaatggaa
     3781 aaacgttggt tatatagtcg ttttttgtta tttttgtaac agtaaatcag aaatatatcc
     3841 atcatgagtg aatttaaaat acgtgcttac gggcgcatgg aactggcgca actctattct
     3901 ccgcaactaa ctgacatcgc tgcctatcga aagatgaaga aatggatctc tttgtgtccc
     3961 ggacttctac aacgcctgta cgacttaggc tacgaatcaa agcgacgctc attcacaccg
     4021 ttggaggtga gagtcattgt ggatgcttta ggagagcctt aaataaagcg tcgctttatg
     4081 gtgtataaag caccgcttta cgatgtctaa agcttagctt tacacctcct aaagcgatgc
     4141 tttatgcagg acaaacgatt gtttcagtca aaacggatgt ggtaattgaa atgactactg
     4201 catccgtaag taaaacgggt acagtgggta cactttttcc ggttcactca tacacacacg
     4261 cacgcgcgta caaccctttg ccgtctatac tgactaatat tccgcgcttg gtgagccgtt
     4321 tcaaccaagt gagggctgtg ttttccttaa ttcccatggc aactgcttct tccagtaact
     4381 gtgtacgagt aaattcatca cccagtttct ggaagagata atcacgatcg gcattaggac
     4441 ggtggctgat ttctgtattg gggaggaacg atagaatatg cgtggcatga cagtagagag
     4501 gttccgcaag actaagcaca gcatgaaagt cttcctgtga aatggataca tcccaacgag
     4561 tgatgatgtc atctttgcgg ttgtccgcag gaatctcctt gtccggtgtg aaaggagagg
     4621 tgggggaggt cttgaagtcg tagggctgcg ggctttcgag ggcacgcaat acggctactt
     4681 ccgacatgat tctgcataga ttgacggcca gacgtgccac aaaactatac atttcccttc
     4741 cattagctac actggagcgt tcaaacaagt tggaaaagac ggtgtcgatt tcttcttttt
     4801 gttcatccgt gagttgcagg gtatgaatgc cgtgcgcttt tatcacgctc aacttttctt
     4861 tccattccag tcccatagcg gtgaatatct cctcccaatc tatctcgttg tccataaatt
     4921 ggctgatcca tttacttatt ccgcacatgt aataatataa ttggcgggag tatgatccgt
     4981 cttctgccgt cggaatgaaa gtttgcacct gcgacggcgt acccgaaatc agaacggaaa
     5041 gatagctttt cttcacttcc cggtattcct ggtcggtgcg gcggttgtag gacaagcggt
     5101 cgtggtcgaa cgctttgcgc agggtatcgc tccaatgacc gtgatccgat ccgatggcgg
     5161 tggaaagggt gtccgcttcc gcttcgcaga taagtccggt tccgtcggag tccatgatgt
     5221 tttgtaggat acccgtaccg gtgttgttgc ccgaaatgag gaacatcctg ttagggggca
     5281 tttgtggagc ctcctttttg gttcgttctt ttcccattgc atcgtactcg gctttctctt
     5341 ttttgtatgc tttcatctgt atggtcactt ctttgcgaat ctcgtcgtgg ataggttcca
     5401 cgagtaagcg gatgtaggaa aggatacctt tgccggaagc cgaaggagcc actacgaaac
     5461 attggaggct ggggtgatgg tatttgccgc catataggca tcgcacgtgg cgcgacatac
     5521 aggcacccag ggcagtgagc gctcccaata gcatgatgtc gtgttgtatt gggctgctcc
     5581 cggcttttat gatacgttgc aaaaattccg gccagtcgtt tttcggaaaa gtgggcaatt
     5641 gatgttgcgg ttcactgccc ggcaatagtt cttcttcccc ttctctttct tcggagatat
     5701 tgtcattccc taccttatta tacgcgcccg tgtgtggggg aaatttgcgt gctgtacctg
     5761 ctgtaccttt tgtacctgtg ggatgtttgg gcatttcttc tatgcagatg cttactcccg
     5821 tcgcttcggc caggtggaaa gcggtgccca ggtgcacttc tccacgttgg gtgtggagtg
     5881 cgttggagaa tacccgttcg gcatgttcgc gctgatactt gggagacacc cggcacaggc
     5941 gatgaaaaaa gtcacgtcct gcttcaccgc aatccgttgc gatggcgaat gacaattgta
     6001 cgtattcaag ataagtggga gcaatgtccg ctcctgccgc ttcgactgct tcggtgagac
     6061 ggcgtaaaga ttcaatatcg gtcattttga tttatgattt ttgatttatg atttattcgt
     6121 tggtggttct gaacaatgct tccgggtcgt aactaaggaa acaggatctc acgaggtctt
     6181 tgccggagaa atctactttg gattttgttt cggaagaaac tgctgttacc gtattgtatg
     6241 ccgtctctac gtaccgcatc gcccaactca tgttgtctgt gatatttggg atgtcatttg
     6301 tcgtggagga ataatggcag ggaacaaatg cctttacacc cagtccgctg gggctgacaa
     6361 aggtgagtac aggttgtagg agaggatcgt catagagcat acgtcgcatt tccactgctt
     6421 cctgataaga gtggagaccg tccacatcta ctatcaccag gtgagacggg gagacgaaat
     6481 ccttactgct acggcgggtg aatgtgccgc agggggtcac atacggtagt aatgacgctt
     6541 tggcggttcg tatatcttcg gagttgcgta cttgttcggt cagggctttg agattctcgt
     6601 tgcaagtaat catttggaaa acttgttcga tggagacttc gcagaagggg ataagcgtgg
     6661 gaggagtcat cagtcggcct tgtttgtctt tgataggagc gataggtggc atgaaatagg
     6721 acattctgta gttgtttggc atcattttct ttttgtttca agttaaaatg tttatttttg
     6781 caaaaaaata tgagtgtgtt tcaaaacacg gcgtaaaatt agtaaatgca aaatagacat
     6841 cgtcccgaca tgttgggatg aaagtgaaaa taattaaccg ttacggtgta attttaacaa
     6901 taaaaaagaa tggaaaatga aaaaggttta tatgtagctt taggagttta cataggagag
     6961 ttgcaaaagc gtgcggattt gaaaaatgac gaaatacgga agagcgtaca catcggccac
     7021 tctactttta atgatttaaa aaaggggcaa aacgcccatt gagtgattac gtaaaagtgg
     7081 tggagtgctg tctggatgcc ttcaatgaag aggaagccgg agttatctgg gatgaatgga
     7141 ggagaatgta ttttcgatac agaagaagaa aagaggagga gagaggagaa cggtgaaaaa
     7201 acagataagg taaaagtggc aggcgggaaa aagtttcccg cctgcggtct ttatgaatgg
     7261 atttttttgt agctttgtga aaaataagat tgatatggaa gatttgtctg gtaattttta
     7321 taatttaaga aaaagaagcg tatgagtagc aagatatacc ccattggcat acagaacttt
     7381 gaaaaaatcc ggaaagacgg ttatttctat attgataaga ctgctttgat ttatcagatg
     7441 gtgaagacag gcagttatta tttcttgagc cgtccccgtc gttttggaaa aagtctgttg
     7501 atatctacgc ttgaagcgta tttcttgggc aagaaagaac tttttgaggg cttggccatg
     7561 gaaaagctgg aaaaggattg gactacatat cccatttttc atatcgatct taatacggag
     7621 aagtatgata cgcgggagag cctggatagt atattgaatt tcacattgga gaaatgggaa
     7681 cagcaatatg gcaccgctcc gtcggaaaca acttttgcat tgcgttttcg cggccttatt
     7741 gaacgggctt atgagcaaac cgggcagcgt gtggtcattc tgatagatga atatgataag
     7801 cccatgttac aagcaatggg taacgaggag cttcagaagg aattccgtaa taccatgaaa
     7861 gctttttata gtgtgctgaa gactatggac ggttgtattc agtttgcatt tttgacggga
     7921 gtgacgaaat ttggtaaggt aagcgtgttc agcgatttaa ataatctcga tgacatctca
     7981 atgcggaagc aatacgtgga tctttgcgga gtttctgaaa aagaattgca tgataatctg
     8041 gaaattgaac tgcatgaact ggcggatgca aaggagctga cttatggtga actgtgcaat
     8101 agattgaggg agtactatga tggctatcat tttacataca attctatcat taaatttttg
     8161 cttccctttt atgcgaacac caatgcggta gagtcggagt ttgaaatata gaactttaac
     8221 gcgaaaatgc gtaatattga gaaatggata gtggaataat ggtgaaataa cgatagaaaa
     8281 tcccggctga agaaataaaa cggctgggat tttttgttta ggatgtctat ttgccattct
     8341 tgaaaaatat caaatggtag ctatatcttt tccgtgtgcg ataacgaaaa cgcaaaaaat
     8401 aacaatttat tatgtagaaa aagttggggg aatgcttcgt agttcacaaa taatgattaa
     8461 atttgccgcg atttgtaatg cggagtttgc aaaatgacga ataatactat aaagcatcta
     8521 ggtattgtgg aaaacatcca aggttctcat ctgtcggtga ggattgtcca gacatcggct
     8581 tgcgcggctt gtagcgcaaa ggggcattgt tcctcggcgg atagtaagga caaaatcata
     8641 gatattatag ataccgcggc ttcttcctat caggtgggag agaaggtgat ggtggtcggc
     8701 gaaacgtcga tgggcatgat ggcagtggta ttggctttcg tacttccttt cgtacttctt
     8761 atattttcat tgtttctttt gatggcgtgg atagagaatg agttgtatgc agcacttctt
     8821 tctctggctg tccttatacc ttattatttc gttttgtggc tcaataaaac gcgactcaaa
     8881 caacaatttt catttactat aaaaccaata aataactaaa aacattatga atttgattct
     8941 gattgcagtg atttcattgg gagctatagc gctcgtgctg gccgctattc tttatgtggc
     9001 ttccaagaaa tttgccgtgt atgaagaccc gcggattgct caggtgggag aagtgcttcc
     9061 ccaggctaat tgtggtggat gtggctatcc cggttgtagc ggatttgccg acgcttgcgt
     9121 caaagccggt tcgctggatg gtaaattctg ccccgtaggt ggacaacctg tcatggcaca
     9181 aattgctgat atcctcggac ttgcagccgg tgaagctgaa ccgatggtag cagtggtaag
     9241 atgtaacgga acgtgtgcca atcgtccgcg taccaaccaa tatgatggtg cgaagagttg
     9301 tgctattgcc gcttcgctgt atggtgggga aacgggatgt agttacggat gtctggggtg
     9361 tggcgactgt gtggctgctt gtcagttcga tgccatccac atgaatcctg aaacggggct
     9421 tccggaagtg gatgaagcga aatgtaccgc ttgtggcgcc tgtgtgaagg cttgcccgaa
     9481 agcgatcatc gaaatccgtc cgcaaggaaa gaagtcacgc cgcgtgtata tctcttgtgt
     9541 gaataaagac aagggagctg tggcacgtaa ggcttgtaca gtgagctgta tcggctgtgg
     9601 caagtgtgtg aagacttgtc cgttcgaggc tattacgctg gaaaacaatt tggcttacat
     9661 cgatccgaac aagtgtaaat cttgccggaa atgtgtggaa gtttgtccgc agaatagcat
     9721 tatcgagttg aatttcccgc cgcggaaacc gaaagaagaa gctccggctg ctccgaaacc
     9781 ggctacaaaa gtggaaactc ctgctgcaaa ggctacagaa gctccgaaag taacagaata
     9841 ataacagaaa aaaatacaga actgtatgtt aaagacattt tcaattggtg gagttcatcc
     9901 acacgaaaat aaattgtcgg cacatcaacc tattatcaca gcggaagttc ctgcaaaggc
     9961 tgttattttg ctggggcagc atatcggtgc gcctgcaaaa ccggttgtag cgaaagggga
    10021 tgtggtaaag gtaggcacac ggattgccga acctgccggc tttgtttcgg cagcaattca
    10081 ctcttcggtc agtggtaaag tggcgaagat tgataccata gtcgatgcca gcggttatgc
    10141 gaaacctgcc atcttcattg atgtggaagg cgacgaatgg gaagaaacaa tcgaccgtag
    10201 caccacactg gtgaaagagt gtgaactttc cgcagaagag atcgtgaaga agattgccga
    10261 tgctggaatc gtaggtctgg gcggtgcttg tttccctacg caggtgaaac tttgtcctcc
    10321 tccttctttc aaggctgaat gtgtgattat caatgccgta gagtgtgaac cttacctgac
    10381 tgccgaccat cagctgatgc tggaacacgc ggaagaaatc atggtgggtg tttctatcct
    10441 gatgaaagcg gtgaaagtga acaaggcatt tatcggaatc gaaaataata agccggatgc
    10501 tatcgaactg atgaccaaag tggcttccag ctatgcaggt atcgaagtag tgcccttgaa
    10561 ggtgaaatat ccgcaaggag gtgaaaagca gctgatcgac gcgattacca aacgtcaggt
    10621 ggcgagcggt gcattgccta tctctacggg agcagtcgtg cagaacgtgg gaacagcatt
    10681 tgccgtttat gaagctgtac agaaaaataa gccgttgttc gaacgtgtga ttaccgtgac
    10741 aggaaagtcg gttgcgaaac cttccaactt cctggctcgt atcggtacac cgatgaaaca
    10801 gttgattgac gcttgcggtg gtctgcccga agatacgggt aaggtgatcg gtggcggtcc
    10861 gatgatgggt aaggcgctcg taaatatcga ggttcctact gcgaagggca gttccggtat
    10921 cctgattatg aatcagaagg aagccaaacg tggtgaggcg cagacttgta tccgttgcgc
    10981 gaagtgcgtg agtgcctgtc cgatgggact ggaaccgtac ttgctcggag ccttgtccga
    11041 aaacggagat tttgaaacaa tggaaaaaga aagaatcatg gattgtatcg agtgcggctc
    11101 ttgccagttc acttgtcctg ccaaccgtcc gttgctcgac tactgtcgtc tgggcaaagg
    11161 caaagtaggt gctatgattc gtgcacgtca agctaaaaaa taacgaatat ggaaaataaa
    11221 ttaatcgtat cactatcacc ccacgttcat ggcggagaca gcgtacagaa aaatatgtat
    11281 ggcgtgctga tcgcactgat tccggctttt ctggtgtctc tctatttctt cggactgggt
    11341 gccctgattg tcacggctac ttccgttgca gcttgtttgt tcttcgaatg ggcgatcggg
    11401 aaatatttaa tgaagaaacc taccaccacc atctgcgacg gctctgccat catcacaggt
    11461 gtgttgctgg cattcaactt accgtctaat ctccctatct ggattatcat tctgggtgca
    11521 ctgtttgcta tcggtgtagg caaaatgtct ttcggcggat taggttgcaa tccttttaat
    11581 ccggcactgg caggacgtgt gttcctgttg ctttctttcc cggtacagat gaccagctgg
    11641 ccggtagtcg gacagttgac cgcctatacg gatgctacca ccggtgccac tccgctggca
    11701 ttgatgaaac aagcgattca tgctgcagat aaaagtgcgg ctatggatgc tttaaaccag
    11761 attccggatg cattgagttt gctgatcgga cagaatggcg gatgcttggg tgaagtgagt
    11821 gcattggctc tattgatcgg actggtttat atgctctgga agaagatcat tacctggcat
    11881 attcctgtgt ctatcctggc taccgtgttt atctttgcag gtatcatgca cttggcagat
    11941 ccggaaaaat atgtttctcc gatattgcag ttgctctccg gtggtctgat gctgggtgct
    12001 gtctttatgg caaccgacta tgtgacttct ccgatgagta agaaaggaat gttgatttat
    12061 ggtgtatgta tcggtctgct gacggttgtc attcgtctgt tcggtgctta tcccgaaggt
    12121 atgtcgttcg ccatcctgat tatgaatgcg ttcactccgc tgattaacac ctattgtaaa
    12181 ccaaaacgct ttggggaggt agcgaagaag aaatgaaaaa gttagaatca tctttaaaga
    12241 atatgttgct ggtacttacg ggcgtgactg ctgtctccgt agcgttgctg gcttatgtaa
    12301 atgaactgac aaaaggcccc attgccgaag cgaatgcgaa gacactgaac gaggctttga
    12361 aaaaggttct tcccgaattt accaataatc cggtagcgga aagcgatacg atcttcagcg
    12421 agaaagacgg aaagaagaac gttgacttta tcgtttatcc ggccaaaaat ggcgaagaac
    12481 ttgtaggaac ggccgtcgaa gctaaatcaa tgggatttgg cggcgaactg aaagtactgg
    12541 taggctttaa cgccgaaggt aaaatctata attactcgtt actcgctcac gcggaaactc
    12601 cgggactggg ctctaaagcc gacaaatggt ttggagcata cgacccggcc aagggagaac
    12661 aggctgtgtc tcatgaagag agtaaaaagt ctattttggg gatgaatccg ggtgaagctc
    12721 cgttgactgt cagcaaagat gggggagcgg tggatgccat tacagcttct accattactt
    12781 cacgtgcgtt tctgaatgct gtaaatgctg cttatcaggc ttataaggca gaaggtggta
    12841 aagtgaatgg tgtcagcggt gcttctcaaa aggctacagg cgcagactct gacactgcta
    12901 caggagctac gataaaggtt gaacttactg attcggtcag tgctaaataa gaaaggagac
    12961 agatatgaat aactttaaag taatgatgaa cgggattatc aaagagaatc ctacgtttgt
    13021 actcctgctc ggtatgtgtc ctacattggg tacgacttcg tcggccatca atggtatggg
    13081 tatgggactg gctaccatgt tcgttttgat ctgctcgaat gtggtgatct ctttaatcaa
    13141 gaacctgatt ccggatatgg tgcgtatccc gtcgtttatc gtggtgatcg cgtctttcgt
    13201 aaccttgctt caaatggtga tgcaggcata cgtgccggga ctgtacgcta cgctcggact
    13261 tttcatcccg ttgattgtag tgaactgtat tgtgttggga cgtgccgaag cattcgccgc
    13321 caagaataac gcagttgctt ctatgttcga cggtatcggc atgggacttg gtttcaccat
    13381 tgccctgaca ttgctgggtg ctgtccgtga atttctggga accggtaaga ttttcgatct
    13441 gaccatcatg ccggaagaat atggaatgtt ggtatttgta ttggctccgg gtgctttcat
    13501 cgctttggga tacctcattg cgctgattaa cagtttcaag aaagcctaat tcaattaaat
    13561 aagaaaagaa tatggaatat atattaatat ttatttcggc aatctttgta aacaacatcg
    13621 tgttgtcgca gttcttgggt atctgtccgc tcctgggcgt atctaagaaa gtagagactg
    13681 cgatgggtat gagcgctgcg gttgctttcg tgttgaccat cgctaccatc gttaccttcc
    13741 tgattcagaa gtttgtgttg gatgttttcg ggctgggata tttgcagacg attacgttca
    13801 ttctggtcat tgccggattg gtgcagatgg tggaaatcat tctgaaaaaa gtatcgcctg
    13861 ctctgtatca ggctttgggc gtgttcttgc ctttgattac aaccaactgt tgtattcttg
    13921 gtgtggctat cctggtgatt cagaaagact acgacctgct gacaggtgtt gtgtacgcgt
    13981 tttctacggc catcggtttc ggtctggcac tggtgctttt tgccggattg cgcgaacaga
    14041 tgagcctcgt gaaagtacct aaaggaatgc aaggcactcc gattgccttg attaccgccg
    14101 gtttgcttgc tatggcattc atgggattct ccggcgtggt gtaaggattt acagttgata
    14161 attaaatagg ggattggaag ctctgctgta tggcgtcata cagctttgag tttccaattc
    14221 ttttttatac ctgattgcca cccaatcgta cctaaattac ttttcagcaa ataaaattgt
    14281 ggcaaattat tgctattcca ttttatttcc atacatttgt aactcaaaca atgataagcc
    14341 gagaaactaa ccatttttat aaagtatatg aaagaaagaa ttttagtaac aggcgggaca
    14401 ggatacatag ggtctcatac tgttgtagaa ctacaaaaca gtggatatga agtaatcatc
    14461 atcgataatt tatcaaattc aagtgccgac gttgttgaca atatagagaa agtttccggt
    14521 attcgcccag tttttgaaaa gctggactgt ttggactttg ccggtctgga tgcagtattt
    14581 gcaaaatata aaggaattaa ggcaatcatt cactttgcag ctagcaaagc agtaggagag
    14641 tcggtacaaa aaccgttgct ttactaccgt aataacctgg tttctttgat taaccttctc
    14701 gaactgatgc caaaacatgg agtagaaggt attgtgttct cttcttcttg tacagtatac
    14761 ggtcagccgg acgagctgcc ggtaacggaa aaagctccga tcaagaaagc ggaatcacct
    14821 tatggaaata ccaaacagat caatgaagag attattcgtg atacggtagc ttcaggtgct
    14881 ccgatcaatg cgatcatgtt gcgctatttc aacccgattg gcgcgcatcc tactgcattg
    14941 ctgggtgaac tgcctaacgg ggttcctcaa aacctgattc catatctgac ccagacagcc
    15001 atcggtatcc gtgagaaact tagcgtgttt ggtgacgatt atgatacacc ggacggttct
    15061 tgtatccgtg actttatcaa tgtcgttgac ttggctaaag cacacgtgat tgctatccgt
    15121 cgtatcttgg aaaagaaaca aaaagaaaaa gtagaagtat ttaatattgg tacaggacgt
    15181 ggtgtttctg tattggaatt aataaatggc tttgaaaaag ccactggcgt aaaattgaat
    15241 tatcagattg tcggacgtcg tgcaggtgac attgaaaaag tttgggctaa cccggatttt
    15301 gctaataaag agctgggttg gaaagccgta gaaactttag aagatacttt acgctctgca
    15361 tggaactggc agctgaaact ccgtgaaaga gggattcaat aaaagagaaa cttgttttaa
    15421 ataacataaa agtttaaaca aatcgtgcat gcgatttgtt tatttgatgc taatcgacct
    15481 gaagctgttt atgagtatgc gaatatacgt aaatagtact tatgcctccc cggcatagac
    15541 aggaaagatt gcatagtagt tttgtcgtgt tttattttgt gtttgtgttg tggaggttgt
    15601 gtcaaaacgt tggcacaacc tcttttatat tttacagttc tgcta
//
