LOCUS       c00204_gnlPro..        17047 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CBNCELNM_204.
ACCESSION   c00204_gnlPro..
VERSION     c00204_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 04:01:31
            Original ID  :: gnl|Prokka|CBNCELNM_204
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 7978
            Orig. end    :: 25025
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17047
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[17978:20951]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12973
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17047
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17047
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(1607..2164)
                     /locus_tag="ctg204_9"
                     /transl_table=11
                     /translation="MMYVMRNGCRLGAVLSFLLLSCGVHVHAQRVAVKTNALGWLTASP
                     NVEAEFILGRHVSLNMGVAGNPISTDNFKTTFTHFQPEVRYWLNRPMVSHFLGITAFVN
                     NFNMMVKDVYHKGDAYAAGLTYGYAWVLGEHWNIEATAGIGVMRYRQFKYDKGTPKPKT
                     VNDSKTTIAPVKLGVSFVYIIR"
     CDS             complement(2333..5101)
                     /locus_tag="ctg204_10"
                     /transl_table=11
                     /translation="MRQILLGLCLLCLLNNVSGQENGREIPLPEKMPQEHPRVLTTPDG
                     KQDTWELIKKEKWAKDVFNKLKERTEVYTNLTDAQPAWLLSRLAMSWKSHATELYVKGE
                     TYDHAGGEKAPYPTVRYTGTRGTAATHGRPKLADVVPYDDDENGNVTFCNNALPERPLE
                     SVHPSKTGRNIESLNREILGIACDAAFLYWMTDEEKFAKLAAGVFDTYMTGIYYRNVPI
                     DLNHGHQQTLVGLTSFEVIHEDALHIVVPLYDFLYNYLKTNYPEKMDIYAGAFKKWADN
                     IIANGVPHNNWDLLQARYIMNVGLVLEDNKEYADGKGREYYIDYVLNRSSIRQWSLTRL
                     ADYGFDSTTGIWAECPGYSSVVINDYANFANQFDNNLKYDLVKAMPVLSKAVAATPQYL
                     FPNRMICGFGDTHPSYLNTNFFIRMIQNAQANGKTEQENYFTALLKCLNPEIDNEKGEK
                     NNVRVSVNSFFEDKPLSLNPKVKAGKIEDYVSPLFYAPNVSWLVQRNGMHPRHSLMISL
                     NASEGNHMHANGISMELYGKGYVLGPDAGIGLTLYSGLDYAEYYSQFPSHNTVCVDGIS
                     SYPVMKSNHSFDLLSCFPASAEPGKEFTSVTYSNVYFREPESRADQTRMMSIVTTGSET
                     GYYVDVFRSRKERGGDKMHDYFYHNLGQTMTLTAADGTDLNLQPTEELAFAGAHLYGYS
                     YLYDKKVAATGKDVKATFTIDMKDKGGDDIVMNLWMKGEPDRDVFTALSPMTEGLSRTP
                     GMPYNIKEQPTLTFVVRQHGEAWTRPFVAVYEPSTKKEPSAIQSVSYFDVEETVLKDFA
                     GICVKSKNGRIDHIFSLSDATQTATYQGMKVKADYAVVSNEYAGNRTLFLGNGTQLVAP
                     KVTVHTDQAGNVLLEKKQGKWYILSSVPCTVVINGKKIKSGITSQLTLLPV"
     CDS             5191..7170
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH_4Fe-4S"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg204_11"
                     /sec_met_domain="Fer4_7 (E-value: 3.1e-10, bitscore: 31.2,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 7.7e-11, bitscore: 32.4,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.1e-50, bitscore:
                     161.1, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00056, bitscore: 11.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 4e-12, bitscore:
                     36.8, seeds: 130, tool: rule-based-clusters)"
                     /sec_met_domain="NADH_4Fe-4S (E-value: 5.4e-34, bitscore:
                     106.6, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPERYFYSNKELYLQKNRLTILILMKILSIHDLATIRKRAEHNLS
                     LREESNEKVTEKCYGLASGAQHLQILICGGTGCKASSSQGITDNLLKAIQKNEITDKVE
                     VITVGCFGFCEKGPIVKIIPDNTFYTQVTPEDAEEIINEHIIGGRRIERLLYVDPKTEH
                     TVSDSKHMDFYRKQLRIALRNCGFIDPENIEEYIAREGYFALADCLLNKQPTDVIDIIK
                     RSGLRGRGGGGFPTGLKWEFANKQQSDVKYVVCNADEGDPGAFMDRSIMEGDPHSIVEA
                     MCVCGYSIGSTKGLVYIRAEYPLAINRLKTAINQAREYGLLGDHILGTDFSFDIEIRYG
                     AGAFVCGEETALIHSMEGKRGEPTLKPPFPAESGYLGKPTNVNNVETLANIPIILTKGA
                     DWFATIGTERSKGTKVFALAGKINNVGLIEVPMGTTLREVIYEIGGGIKGGKKFKAVQT
                     GGPSGGCLTEKHLDTPIDFDNLLSAGSMMGSGGMIVMDEDDCMVSVARFYLDFTVEESC
                     GKCTPCRIGNKRLLELLNKITEGKGTEKDLDTLATLGQVIKDTALCGLGQTSPNPVLST
                     LDNFYDEYMEHVRDKTCRSKQCKSLLTYTISPERCIGCHLCAKNCPADAISGLVRKPHV
                     IAPDKCIKCGMCMARCKFNAILVC"
     CDS             7292..7558
                     /locus_tag="ctg204_12"
                     /transl_table=11
                     /translation="VSHRPERHLHKEQSCFLSHLRGRGYRTPQSGSCLRYPLHGRNGSE
                     NQYATCDERTQSGSRTYPVGSSQRLSHLPQMWQLRTSDISATL"
     CDS             complement(7548..7790)
                     /locus_tag="ctg204_13"
                     /transl_table=11
                     /translation="LSAIGTFAFRHHPVKGRGYRRVESATDGTERTDCLNIVADTFAAA
                     TENTFIHVAHDGGSDFPLAGRELASIERHFADIKA"
     CDS             7809..8948
                     /locus_tag="ctg204_14"
                     /transl_table=11
                     /translation="VGALTERDYTNRLLDDLANPDKVVIVQTAPAVRAALGEEFGFPPG
                     TLVTGKMVYALRELGFDYVFDTDFAADLTIMEEGSEILNRLTRYLNGDKSVRLPILTSC
                     CPAWVNFFEHHFPDMLDIPSTARSPQQMFGSIAKSYWAEKMGIPREKLVVVSIMPCLAK
                     KYECARDEFKVNGIPDVDYSISTRELARLIKRANIGFPLVLDSPFDNPMGESTGAGVIF
                     GTTGGVMEAALRSVYEIYTGESLKNVNFEQVRGLNGVRRATINLNGFELKVGIAHGLGN
                     ARHLLEDIRNGHNEYHVIEIMACPGGCIGGGGQPLHHGNSEILYARANALYREDANKPL
                     RKSHENPYIKTLYEEYLGKPLGEISETLLHTHYFNKSMD"
     CDS             8967..9443
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg204_15"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 1.1e-54,
                     bitscore: 174.8, seeds: 130, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDIKLACDVAEQVRTICDKHGNNPGELINILHEAQHLHGYLPEE
                     MQRIIASKLNIPVSKVYGVVTFYTFFTMTPKGKHPISVCMGTACYVRGSEKLLEEFKRV
                     LGIEVGETTPDGKFSLDCLRCVGACGLAPVVMIGEKVYGRLQPIDVKKIIEELE"
     CDS             10001..12229
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg204_16"
                     /sec_met_domain="Gly_radical (E-value: 9.4e-47, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1171.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEVKKEDLRNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             12245..12973
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 73.2;
                     E-value: 8.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg204_17"
                     /sec_met_domain="Radical_SAM (E-value: 1.2e-29, bitscore:
                     94.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLMRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(13045..13491)
                     /locus_tag="ctg204_18"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRADRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDENGKAADTRTSRQKEAMHRLVSELL
                     QRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIEEFES"
     CDS             complement(13666..14142)
                     /locus_tag="ctg204_19"
                     /transl_table=11
                     /translation="VPRKNPAKKDESAKYYAQAQASGELDFEELCEGITSRSTCTETDV
                     RAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLITAAHIIFRPG
                     KTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAPDPAA"
     CDS             14363..14593
                     /locus_tag="ctg204_20"
                     /transl_table=11
                     /translation="MYYPDQPFHIRTYKKSELAHLYNPNVCLKVALQILRRWIVYNLPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             complement(14891..15382)
                     /locus_tag="ctg204_21"
                     /transl_table=11
                     /translation="VRGMVVECHLFGEGIVVWCCRLFLFAGCPFLLLRLEEHRWLFHDD
                     SCGIGIEINIRIVREQASAANILSGSVDLNSAELGIKGSDFVISGMMEIFNFLNRFGQC
                     PVRPAYTYHDFQSHSFGTDESDAGVGTLFCQCEDACQCFLCLMVDVYHDVSQILDESCV
                     "
     CDS             16112..16798
                     /locus_tag="ctg204_22"
                     /transl_table=11
                     /translation="LRAYLSTGLINPNNKDDLAKIAQAMLINLDEFEGMNGRELNIFKD
                     LVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVDSMEFIKIN
                     YAQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPERFEKV
                     HYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIIDTEQVK
                     SNRLYE"
ORIGIN
        1 ttctcgaatc cggagcctct ctctgtatag ttgctaccgc cagttcattg gctgcatacg
       61 taaagttatc atagagttca agtgcttctc tgcaatattt ttctttttca ttcagatcct
      121 ttgcggttgc aatcatacgg taaaactcaa atcgggtcag atctttcgga tgcctcttat
      181 agagttgtct gatttcctcg tccgtcagag aacggaaaat ggaatatccg tatgtgtatt
      241 gcacttttct taatttaggc agatacactt cggctatctc tttatagaaa tgtttcgttt
      301 ttaacgcatg attcaatcgg tacggagtag cctcgtattg tttgattagc tcttccacac
      361 ttttagccaa gtcatgttta gagtcctttt tcagtaatcc taccacttct ttccaggaag
      421 caaccgatgc atcagatttt acttccagaa gtttacgtgt tccgggatct aattgcgaca
      481 agatacgttc caatgcttta tccgtacgta atttggccag ttttaaattc gattcataag
      541 aaccgtccgg tgaagcaaca cccgttatat ggaaactctt taaagaagca tccggattcg
      601 tttcaatgct acgcaattcc tgattcaaac gattcagttc cacttgattc cgtggatttt
      661 tatcatccag attggcttta cctacaacga atgtcagatt cacttctcct ttagtgtccc
      721 tcaactgcat cacaggtttc ggaaggtatt tctcatccgt cagcttgaaa gcggagaatt
      781 tatattccaa gaaacgaagc ggattgactg tcccccgtgc aatagagaaa gaatcacgat
      841 aaattatatt ccgataattc tccatggcaa gatgcacatc cgcccggtaa tcatgttgca
      901 ggtactctat ataaatcgaa tcatggtaag ctatgatgtc tcctttacgg gaagaagtcg
      961 tttttacctg aatatattca tgcaaaggat cttcttcaat ctcataatcg tacatccggc
     1021 gttgtgttgt attatacgtg cctccgtcga aaaccacagg acgcatcaac agccgtttct
     1081 ttaatgtcac atcataaatg gaaggttgca ataccaggcg acgatgcgaa ttaaacattt
     1141 ccttcggcac cgggacacgg gttttcagat ggaaatagtt tcctttgatt tcaatgtccg
     1201 taggttcggg aaccacttta tcttttatct tcgaagtaat cgttacttca tccaattcga
     1261 tcacagcatc tctcaatatg acattgagaa tctgttttcc atccactttc accgtcttat
     1321 cctcataacc gacgcacgta aacttcaatg aaccgttttt atctaccaat acactgtatc
     1381 gaccatcttc gtcggacatt tctatgcgtt catcatttgc aggattcaac acatttacat
     1441 tcggaatact cttgccttgt ggatttgtga tgtgtccctg tacgcggata cgttgcgcgg
     1501 atacacttat acaagatgcc agcattgcca tgagaagtat tcctattaat ctatcatgtt
     1561 ttaaattgat tttcattctt ttttggctaa ctaatattcg ttctattcat cggataatat
     1621 aaacaaagga cactcccagt ttaacaggcg caatagtagt cttgctatca ttgacagttt
     1681 tcggttttgg agtaccctta tcatacttaa actgacggta acgcatcaca cctattccgg
     1741 ctgttgcctc gatgttccag tgctctccga gaacccatgc atatccatag gtcaaaccgg
     1801 cagcatatgc atcccctttg tgatacacat cctttaccat catattaaaa ttattcacga
     1861 aagcggtgat gccgagaaaa tggctcacca tcggacgatt tagccaataa cgtacttccg
     1921 gctgaaaatg cgtgaaagtc gttttaaaat tgtctgtact gattggattc cctgctactc
     1981 ccatatttaa ggagacatgg cgacccaaaa taaactccgc ttcgacattc ggactggctg
     2041 tcagccatcc caatgcgttt gttttgactg ctactcgttg cgcatgtaca tgtacaccgc
     2101 aagataataa cagaaatgat agcacagccc ctagcctgca accattccgc attacataca
     2161 tcataattta tttcccacta aatatttccc actaatactt acccataaaa agggctttct
     2221 gtctgtttcc cttaaacatc agacagaaag ccgcaaattt agaaaaaata tggcatttaa
     2281 aacgtttgaa tacgtttttt tattgcattt ttttcattca aaatcatttt aatcagacag
     2341 gcaataacgt gagttgcgat gttattcctg attttatctt ctttccatta ataaccaccg
     2401 tacaaggaac agaagaaagg atataccatt ttccctgttt cttttcgagt aacacattgc
     2461 ccgcctgatc cgtatgaacg gtcaccttgg gtgcaacaag ttgtgttccg ttccccagga
     2521 ataaagtccg gtttcctgca tattcattgc tgacaactgc atagtctgct tttactttca
     2581 ttccttgata agtggcggtc tgcgtagcat cagacaagga gaaaatatga tctatacgcc
     2641 catttttgct tttcacacag ataccggcaa agtctttcaa aacagtttct tccacatcaa
     2701 aataggatac agactgaatg gcagacggtt ctttcttcgt acttggttca tagactgcga
     2761 caaaaggacg agtccacgct tctccatgct gacggaccac gaaagtcaat gtcggttgtt
     2821 cttttatatt atatggcata ccaggtgtac gacttaaacc ttcggtcatc ggtgacaagg
     2881 ccgtgaaaac gtcacgatcc ggttcccctt tcatccagag attcattact atatcatccc
     2941 cacctttatc tttcatgtcg atggtaaagg tcgcttttac atctttaccg gtagccgcta
     3001 ctttcttgtc atataaataa gaataaccat acagatgcgc tccagcaaaa gcgagttctt
     3061 ctgtcggttg aagattcagg tctgtaccat cagctgctgt caatgtcatg gtctgtccga
     3121 gattatgata gaaataatca tgcatcttat cccctccacg ctctttccgg ctccggaata
     3181 catccacata atatcctgtc tcggagccag tggtaacaat gctcatcatt cgggtctgat
     3241 ccgccctgct ttccggttca cgaaaataga cattgctgta agtcacagaa gtaaactcct
     3301 ttcccggttc tgccgaagca ggaaaacagg aaagcaagtc aaaagaatga ttgcttttca
     3361 ttaccggata gctcgatatt ccatctacgc atactgtatt gtgacttgga aattgagagt
     3421 aatattcggc ataatccagg ccgctataca aagtcagacc aattcctgca tctggcccaa
     3481 gcacatatcc ttttccataa agttccatgg agatgccgtt agcgtgcatg tgatttccct
     3541 cactggcatt cagagaaatc atcaggctat gacgcggatg cattccgttc cgctgcacca
     3601 gccatgacac attgggagca tagaataaag gagaaacata gtcctctatc ttccctgctt
     3661 tcactttcgg attcagactt aacggtttat cttcaaagaa agaattgaca gatacacgca
     3721 cgttattctt ctctcccttt tcattatcaa tttcgggatt caagcatttc agcaaagcag
     3781 tgaagtagtt ctcctgttcc gtcttaccgt ttgcctgcgc attctgtatc atgcggataa
     3841 agaagttcgt attcaaatag cttggatgcg tatctccgaa cccacaaatc atccggttgg
     3901 gaaaaagata ttgcggagtg gctgccactg ctttcgacag tacaggcata gcctttacca
     3961 aatcatattt caaattatta tcaaactgat tggcaaaatt agcataatcg ttgattacca
     4021 cactgctata tcccggacac tctgcccaga taccagttgt tgaatcaaag ccataatcgg
     4081 caagacgagt cagactccat tgacggatac tggaacggtt caacacataa tcaatataat
     4141 attcacgtcc ttttccatct gcatactctt tattatcttc aagcaccagt cccacattca
     4201 tgatatatcg tgcctgcaat aaatcccagt tattatgagg gactccattc gcaatgatgt
     4261 tatccgccca tttcttaaat gcaccggcat agatgtccat cttttccgga tagttggtct
     4321 tcaggtaatt ataaagaaaa tcatacaagg gaacaacgat atgcagggca tcttcgtgaa
     4381 tcacttcaaa agaagtcaat cccaccaatg tctgttgatg accatgattc aggtcaatgg
     4441 gaacatttct gtaataaatt ccagtcatat acgtatcaaa cacaccggca gccagtttcg
     4501 cgaatttttc ctcatctgtc atccaataga ggaaagctgc atcacaagct attcccagaa
     4561 tttcccggtt cagactttcg atattccgtc ccgtttttga cggatgtaca ctttccaaag
     4621 gacgttccgg caatgcatta ttgcaaaaag tcacatttcc gttttcgtca tcgtcataag
     4681 gcactacatc tgccagtttg ggacggccat gagtagcagc cgttccacgt gttcctgtat
     4741 aacggacagt cggataagga gctttttcgc ctccggcatg atcgtaagtc tcacctttca
     4801 catatagctc ggttgcatga gatttccaag acatggccag acgggataat aaccatgcgg
     4861 gttgagcatc cgtcagattg gtatatactt cggttcgttc cttcaattta ttgaatacgt
     4921 ctttcgccca tttctctttt ttaatcagct cccacgtatc ctgctttcca tccggtgtag
     4981 tcaacactct cggatgttct tgcggcattt tctccggcaa cggaatttcc cgtccgtttt
     5041 cctgtccgga tacattattc aataagcaaa gaagacatag tcccagtaaa atttgtctca
     5101 tactttatat ttcattttta ggtttactac ctattaaata cgaagataga gaattattta
     5161 cctaattact ttcattaaga cctgttttat ttgcccgaac gctactttta ttcaaacaaa
     5221 gaactatatt tgcaaaaaaa ccgactaaca attctgatac ttatgaaaat tttatctatc
     5281 catgatttgg caacaatcag gaagagagca gagcacaatc tttcattgcg cgaagaaagt
     5341 aatgaaaagg tgactgaaaa gtgttacgga ctggcatccg gtgcgcaaca tcttcagatt
     5401 ctgatctgcg gtggtacagg ctgtaaggca tcttccagcc agggtattac agacaatctt
     5461 ctaaaagcca tccaaaagaa cgaaatcacc gacaaagtag aagtcatcac cgtaggctgt
     5521 ttcggcttct gtgaaaaagg tcctatcgtg aaaattatcc ccgataatac cttttacacc
     5581 caagtcactc ccgaagatgc ggaagaaatc atcaacgagc atatcatcgg aggacgaaga
     5641 atcgaacggt tgctgtatgt agatcctaaa acggaacata ccgtcagcga ctccaagcac
     5701 atggatttct accggaaaca actccgcatc gcattgcgta actgtggttt tatcgatccc
     5761 gaaaatattg aagagtatat cgcccgtgaa ggatactttg cattggccga ttgcctgctt
     5821 aacaaacagc cgacggacgt tattgatatt atcaaacgtt cgggacttcg cggacgtggc
     5881 ggtggcggtt tcccgacggg actgaaatgg gaatttgcca acaaacaaca gtcggatgtc
     5941 aaatacgtgg tttgtaacgc cgacgaagga gatcccggtg cattcatgga ccgttccatt
     6001 atggagggcg acccacattc gattgtagaa gcgatgtgtg tctgcggtta ttccatcggg
     6061 tccaccaaag gattagtata tatccgtgcc gaatatccgt tagctatcaa ccgactgaaa
     6121 acagctatca atcaggcacg cgaatacgga ttactgggag atcatatctt aggaacagat
     6181 ttcagtttcg acatagaaat acgatacgga gccggagctt ttgtctgcgg agaagaaact
     6241 gcccttattc attcgatgga aggaaaacga ggagagccga ctctgaaacc tcccttccct
     6301 gccgaatccg gttatctggg aaaaccaacc aatgtaaata atgtggaaac acttgccaat
     6361 attcccatta ttctaaccaa aggagccgac tggtttgcaa cgattggcac agaacgttcc
     6421 aaaggaacca aagtgtttgc tcttgccgga aagattaata atgtagggct gatcgaagtg
     6481 ccgatgggaa ctactcttcg ggaagtaatc tacgaaatcg gaggaggtat caaaggcgga
     6541 aagaaattca aagctgtaca aacaggagga ccgtcaggcg gctgtctgac agaaaaacat
     6601 ctggacactc ccattgactt tgacaacctt ctctcggccg gttccatgat gggttcagga
     6661 gggatgattg tcatggatga ggacgactgc atggtatccg tagcacgctt ttatctggat
     6721 tttacagtgg aagagtcctg cgggaaatgc acaccttgcc gcattggaaa caaacgtctg
     6781 ctggaactac tgaacaagat tacggaagga aaaggcacag aaaaagacct ggacacactt
     6841 gccactttgg gacaagtcat caaagatacg gccctctgcg gactgggaca aacctctccg
     6901 aatcctgttt tatccacatt ggataacttc tacgatgaat atatggaaca cgtgcgggat
     6961 aagacttgtc gttccaagca atgtaaatca ctattaacgt ataccatcag tccggaacgt
     7021 tgcattggtt gtcatctatg cgccaaaaac tgtccggcgg atgctatcag cgggctggtg
     7081 cgcaagccac atgtcattgc tcccgataaa tgtatcaagt gcggtatgtg catggcacgc
     7141 tgcaaattca acgctattct tgtctgctaa aatcgattac tatggaagat aaacaaatca
     7201 cactccagat agacggtcat ttcatcaccg tccccgaagg aagtaccatc cttgaagccg
     7261 ccacgaaaat cggcatcaac ataccgaccc tgtgtcacat cgacctgaaa ggcacctgca
     7321 taaagaacaa tcctgcttcc tgtcgcatct gcgtggtcga ggttatagga cgccgcaatc
     7381 tggctcctgc ctgcgctacc cgttgcacgg aaggaatggt agtgaaaacc agtacgctac
     7441 gtgtgatgaa cgcacgcaaa gtggtagccg aacttatcct gtcggatcat cccaacgact
     7501 gtctcacctg ccccaaatgt ggcaattgcg aacttcagac attagcgcta cgctttaata
     7561 tccgcgaaat gcctttcaat ggaggcgagc tctctccccg caagcgggaa atcactgcct
     7621 ccatcgtgcg caacatggat aaatgtattt tctgtcgccg ctgcgaaagt gtctgcaacg
     7681 atgttcagac agtcggtgcg ctcggtgcca tccgtcgcgg attcaacacg acgatagccc
     7741 ctgcctttga ccggatgatg acggaaagcg aatgtaccta ttgcggacaa tgcgtagctg
     7801 tctgtccggt gggtgcactg accgaacgcg attatacgaa ccgtctgctc gacgacttag
     7861 ccaacccgga taaagtggtg attgtgcaaa cagcccctgc cgtacgtgct gccctgggcg
     7921 aagaattcgg ttttcctccc ggcacactgg taaccggaaa aatggtttat gccctgcgtg
     7981 aactgggatt cgactatgta ttcgatactg actttgccgc cgacctcacc atcatggaag
     8041 aaggatcgga aatactaaac cgtctgacgc gctatctcaa cggagataag tccgtacggt
     8101 tacctatcct gacctcctgc tgtccggcat gggtgaactt cttcgaacat cacttcccgg
     8161 atatgctgga cattccatcc accgcccgtt caccgcaaca gatgttcggt tctatcgcca
     8221 aatcctattg ggcggaaaag atgggaattc ccagagaaaa gctggtagtt gtatccatca
     8281 tgccctgtct ggcaaaaaag tatgaatgtg cccgcgatga atttaaagtg aacggtattc
     8341 ccgacgtaga ttattctatt tccacccgcg aactggcacg actgattaaa cgcgccaata
     8401 tcggcttccc gctggtactg gacagcccgt ttgacaaccc gatgggtgag tcgaccggtg
     8461 ccggcgttat tttcggtaca acaggtggtg taatggaagc tgctctccgt tctgtttatg
     8521 aaatctatac cggagaatct ctgaaaaatg taaacttcga acaagtacgc ggacttaacg
     8581 gtgtccggcg tgctaccatc aacctaaacg gatttgaatt aaaagtaggc atcgcacacg
     8641 gactaggcaa cgcccgccat ctattggaag atatacggaa cgggcacaac gaatatcatg
     8701 taatcgaaat tatggcttgc cccggaggtt gcatcggagg aggcggacag ccattgcatc
     8761 acggcaactc ggaaatattg tatgcacgcg ccaacgcact ctaccgcgaa gacgccaaca
     8821 agcctttgcg caaatcgcac gagaatccgt acatcaagac cttgtacgag gaatatctcg
     8881 gcaaaccact gggcgagata tcggaaacgc tattgcacac gcactatttc aacaaatcta
     8941 tggattaact ttaaacgaag agtaatatgt cagatataaa actagcctgc gatgtggcag
     9001 aacaagtccg aacgatttgc gacaagcacg gaaacaaccc gggcgaacta atcaatattt
     9061 tgcacgaagc gcaacacctg cacggctacc tgcccgaaga gatgcaacgc atcatcgctt
     9121 ccaaactcaa tatccccgta tcgaaagtat atggagtggt caccttctat accttcttca
     9181 ccatgacccc gaaagggaaa catcccatct ccgtctgcat gggtacggca tgttacgtgc
     9241 gcggctccga gaagttgctc gaagaattca aacgcgtact aggcatcgaa gtcggcgaaa
     9301 ccacaccaga tggaaaattc tcattggact gcctgcgctg cgtaggtgcc tgcggactgg
     9361 ctccggtagt gatgattggc gagaaagtgt acggaagatt gcaaccgata gatgtgaaga
     9421 agattatcga ggagttggag taaatgtccg gaataaaaag cggctgcttt gaaaaaccaa
     9481 ggcagccgct ttcaaacatt tttttaacaa caaacaaaaa agcggagaga acgagattcg
     9541 aactcgtgat accctttagg ggtatacacg ctttccaggc gtgcctcttc aaccactcga
     9601 gcacctctcc ttataattac caactagaga acaactctct ataaaaacag aaagcagcaa
     9661 aaagctgctt cctagcggag agacagggat tcgaaccccg ggtacctcgc ggtacaacgg
     9721 ttttcaagac cgccgcaatc gaccactctg ccacctctcc aaaacttcct tttcagaagt
     9781 gcttttcgtt aaaagcggtg caaaggtacg aatatatttt aaacctacaa gagttttcac
     9841 aaaaaaaatc acgaacatca tttccaaaga atagcaatat ctaggtattt tatgttgaaa
     9901 agcataaaat agagcatatt tatgctgatt atatgaaaaa acgttgtaac tttgtgcgct
     9961 ctaaagaaaa ggataactac aacctctaat tttatcattt atggaattaa ataagatctt
    10021 taaagacggt ctttggagca cagaaatcaa cgtaagagat ttcgttagtc acaacatcac
    10081 tccgtattat ggagatgctt ctttcctcga aggacctacc gaacgcacaa aagctgtatg
    10141 gaaccgctgc ctcgaagcac tggcagaaga aagagccaat aacggagtac gctcactgga
    10201 taatgtcacc gtctcaacca tcacttctca taaagccgga tatatcgaca aagaaaacga
    10261 actgatcgtc ggtctgcaaa cagacgaact tctgaaacgt gccatcaaac ctttcggagg
    10321 tatcaacgtg gtgagcaaag cctgccacga aaacggcgtg gaagtggacg accgtgtaaa
    10381 agatatattc actcactacc gcaagacgca caatgacgga gtatttgacg tatataccga
    10441 agaaatccgt tcgttccgtt ctctgggatt cctcaccgga cttcctgaca actatgcccg
    10501 cggacgtatc atcggcgact accgccgtat ggctctctat ggtatcgacc gactgattga
    10561 ggtaaaaaaa gaagatttgc gtaaccttac cggtccgatg accgaagccc gcatccgcct
    10621 gcgcgaagaa gtggcagagc aaatcaaggc attgaaggac atgaaggtaa tgggcgaata
    10681 ctacggactc gacttgagcc gtcctgccta caccgcacaa gaagcagtac aatgggtgta
    10741 catggcttac cttgctgccg taaaagaaca agacggtgct gccatgtcac tgggtaacgt
    10801 ctcttcgttc ctcgacattt atatggaata tgaattgagc aaaggaacta tcacagaatc
    10861 tttcgcacag gagctgatcg accagtttgt catcaaactg cgtatggtgc gccacctgcg
    10921 tatgcaatct tacaacgaca tctttgccgg cgacccgaca tgggtgaccg aatccttggg
    10981 tggacgcctc aacgacggac gcacaaaggt gacaaagact tctttccgct tcctgcaaac
    11041 actctacaac ctcggccctt caccggaacc gaacctgact gtattgtgga gcccggaact
    11101 tccggaagga ttcaaagaat tctgcgcaaa agtatctatc gacacttctt ccatccaata
    11161 tgaaaacgac gacctgatgc gtgaagtacg ccagtctgac gactacggaa tcgcgtgctg
    11221 cgtatcttat caggaaatcg gaaaacaaat ccagttcttc ggcgcacgtt gcaacctggc
    11281 taaagccctg ctgcttgcca tcaacggcgg acgttgcgaa aacaccggca cggtaatggt
    11341 gaaaaacatc cccgtactaa ccagcgacac actgaacttc gaagaagtaa tgagcaacta
    11401 caagaaggta ttgacagaaa tcgcccgtgt ttacaacgaa gcgatgaaca tcatccatta
    11461 tatgcatgat aagtattact acgaaaaagc ccaaatggct cttgtagata ccaacccgcg
    11521 catcaacctt gcttacggtg tagccggact ttctatcgcc ctcgattcac tgtcggccat
    11581 caaatatgcc aaagtaaccg cacgccgcaa cgacatcggt ctgacagaag gtttcgatat
    11641 tcaaggcgaa ttcccttgct tcggtaatga caacgacaag gtagaccacc tgggtgttga
    11701 cctggtctat ttcttcagcg aagaattgaa gaaacttccg gtttacaaaa atgcccgtcc
    11761 tactctgtct ttgctcacca tcacttccaa cgtgatgtat ggcaagaaga caggtgctac
    11821 tcccgacggc cgcgccaaag gtgtcgcttt tgctccggga gccaacccta tgcacggacg
    11881 tgacaagaac ggcgccatcg cctctttgag ttccgtagcg aaattacgtt accgcgactc
    11941 acaggacggt atcagcaaca ccttctctat cgttccgaaa tcactgggag ctactgaaga
    12001 agatcgcgta gaaaatctgg tgacaatgat ggatggttac ttcaccaaag gcgctcacca
    12061 cctgaacgtg aacgtactga accgtgaaat gctttacgat gccatggaac atccggaaaa
    12121 atatccgcaa ctcaccatcc gtgtttccgg ttatgccgta aacttcgtga agttgagccg
    12181 cgaacatcaa ttggaagtta tcagccgtag cttccacgaa cgtatgtaat cagatctact
    12241 caatatgacg ataaacgtac attcatacga aagtatggga acattcgacg ggccgggctt
    12301 acggctcgtc gtttttcttc aaggatgcaa tttccgctgc ctgtattgtg ccaaccccga
    12361 cacgatagcc ggaaaaggag gcacacctac cccaccggaa gaaatcgtcc gcatggctat
    12421 gagccaacgt ccttttttcg ggaaacgcgg aggagtcact ttctccggag gagaacctac
    12481 gtttcaggcc aaagcactag tccctttaat gcgtgaactg aaagaaaagg gaatacatgt
    12541 atgcatagac agcaacggcg gtatctggaa cgaagaagta gaagaacttt tcaaactgac
    12601 ggatcttgta ttgctggata ttaaagagtt caatccggca cgccatcagg cactgaccgg
    12661 aagaagtaac gagcaaacca tccgcacggc agcatggctg gaagaaaacg agaaaccttt
    12721 ctggctgcgt tatgtattag tgcccggata cagcgatttc gaggaagaca tccgccgttt
    12781 aggagaggct ctgggaaaat ataagatggt gcaacgagtg gaaatcctgc cttatcatac
    12841 attaggcgta cataagtatg aagcgatgga gcaggaatac aagctgaaag acgtaaaaga
    12901 aaataccccc gaacaacttg aaaaagccgc ggaggtattt aaagaatatt tcactactgt
    12961 ggtggtcaat tagttgaaga agttgagaat tgagagttaa ctatgcagta taacagtgcg
    13021 cagccaactc tcaactctcc attctcaact ctcaaattct tcaatcacct caaaacaggg
    13081 acactctttg atccgttccc aggggtctac aattccatta taattggtgt cagggctcaa
    13141 gtcccggtga ccgaccacct ttgcatccgg ataacgctgc aacaactcgc ttaccagacg
    13201 atgcatcgcc tctttctggc gggaagtacg cgtatctgct gcctttccgt tctcatccag
    13261 cccgccttca tagcacaccc ctaaactaat cgcattaaaa ccgcgtgcat gagcacccac
    13321 cgtatcttca tccctcatcg gttctatctg tcccgacttg cggatataat aatgataccc
    13381 ccaacaagaa aagccccgaa agcgatgggc agtgtccaca tccttcgccg tgaagtcgcg
    13441 atcagcacgg gtagcagagc agtgaatcac aatcagacta atctttctca tcgtcctttt
    13501 ccctttccgt tgttttcaca ttacacactt ccttatgggt agcattgaag cgcacctctc
    13561 tcacaattct gttccgcttt ctttttccga agaaaggcac aaggaacatg attacatcca
    13621 aaatcttagt tacaatttct ttcatttgat ctaatattaa agttatcatg ctgccggatc
    13681 cggagcttct ccgcttccac caccgtctga accgccaccg gaacctttgt catcgtcttc
    13741 tccttcattg ccgctaccgc ccgtttgggc caccgcacgc gtcgttacct gctggtagct
    13801 aagaatcttc gtgatgtccg ccaacgtctt tccgggacgg aaaataatat gggcagccgt
    13861 aatcagcgaa cttgaaaact ccttgaccga cacagctcct tcactgttca acccgatctg
    13921 caaactgccc aaatcaccca accggactat tcttcccgct ttcaacgcac gcttcgcctc
    13981 ataaagaata cccgaaatgg cggcacgcac atctgtctcc gtacaggtag accgactcgt
    14041 gattccctcg cacaactctt caaaatccaa ctctcccgaa gcctgtgcct gcgcgtaata
    14101 ctttgccgac tcatcctttt tggcaggatt cttgcgcggc actactgaat aagttactgt
    14161 cattgccata ataaaataat tttaagattt cacacatttc gaacgcgttc cttatttgtt
    14221 aacgacataa agataacaca tttttcaccc tccggattcc ccaacgaagt ttcctgatat
    14281 tctatgaata ataacgacgt tattctttta ataaaccatt aattttcagt aactttatag
    14341 cataaaccaa atatcattca ccatgtatta tccggatcag ccgtttcata tccgcactta
    14401 taaaaagtcg gaactagctc atctttacaa ccccaacgta tgtctcaaag tagccttaca
    14461 aatactacgt cgttggattg tctacaacct tccgctcctg caagaactcg aacaagaagg
    14521 ctatcgtgcc cgcaaccgcc ttctctctcc ccggcaagtg gcaacgatca tacgctattt
    14581 gggagaaccc taggaactta atcaaaaaaa cgaaaagttc cattctatta ttttacaaac
    14641 aaatttcttt gcaaccgcaa attaaaaaga acaaaccaac atggagcatt ttaccatctt
    14701 tcaagacttt taccgcgtca tagccgaaat gacagaagaa gaaatcgtat cggccatcag
    14761 caacggcaca taccgggaaa cagtggagga cgtgcgccga atcttcgcgg aacaaggcga
    14821 gaaagcagca aacgaaaaga aaatagaact accggaaatc accttttcag ccaactaccg
    14881 gggaggacgt tcaaacgcaa ctctcgtcaa gtatctggga tacatcgtgg tagacatcga
    14941 ccatcagaca caggaagcat tggcacgcat cctcgcactg gcaaaaaagt gtgcccacac
    15001 ccgcatcgct ttcatcagtc ccaaaggaat gggactgaaa atcgtggtac gtgtatgccg
    15061 gacggacggg acattgcccg aaacgattca ggaaattgaa gatttccatc atgccgctta
    15121 tcacaaaatc gcttcctttt atgcccagct ctgcggagtt gaggtcgaca cttccggaca
    15181 ggatgttagc cgcacttgcc tgttctctta cgatccggat atttatttca atcccgatgc
    15241 cacagctgtc atcgtggaac agccaccgat gttcttcaag tctcaaaaga agaaaagggc
    15301 atccggcaaa aagaaaaaga cgacagcacc agacaacaat cccctcaccg aacaagtggc
    15361 actcaactac cattcctcgc acgcttcctt aatggtgact ctgaactatt atcacaataa
    15421 atccgaaaag tacgtcaccg gcaaccggaa caactacctg cattgcctgg cttgtatgta
    15481 caatcgctac ggcgtccccc aggaagaggc ggcagctttt atcaagagcc agttcaccga
    15541 tcttcccgcg gatgaaatgg acgcactgat cgggagtgct tacggacaca acgaggaatt
    15601 cgacacccgc aagctgaata gtacgcagaa gcgaatatta cagattgagc aacatatcaa
    15661 agaaaattac gatacacgct acaacgaagt gcttcatatc atggaatatc gcagaaggaa
    15721 aacggacacg gagcaaccgg aacctttcca tattctcgac gaaatgatgg aaaacagcat
    15781 ttggatggag atgaacgaac tgggctattc gtgcaccgtc aagacgattc agaatctgat
    15841 ctactccgac ttcagcagca cctaccatcc tattcgcgag tatttagact cgctgcctga
    15901 atgggacgga acggattata tcggtatcct tgccaacagc gtgcatacta gtcaccagaa
    15961 attttgggta gaatgtctgg aacgttatct ggtgggaatg tgcgctgccg ccacacaaga
    16021 tgatgtggtg aaccacactg ttttgttgct ttgcagcgaa atacagaaca ttggaaagac
    16081 tacgtttatc aacaacctgc tgccgcccga attgcgcgcc tatctttcta ccggtcttat
    16141 caacccgaac aacaaggatg atctggccaa aatagcgcag gcgatgctta tcaatctgga
    16201 tgagtttgaa gggatgaacg gacgggaact gaatatcttc aaggatttgg ttacccgcaa
    16261 agtaatcagc atccgcctgc catacgcgcg gcgttcacag aactttcctc acacggcttc
    16321 ttttgccggc acatgcaatt atcaggaagt gcttcacgac accactggta accgccgttt
    16381 tctctgcttt catgtcgact cgatggaatt tatcaaaata aactacgcgc agttgtatgc
    16441 acaaatcaag tatctactca acaagccggg atatcagtat tggttcaccc agtcggaaaa
    16501 ctcacggatt gaagagaaca acgaggattt cattttccac tcaccggaag aagaactggt
    16561 gttgacacat atccgcaaac cggaacgttt cgaaaaggtg cattatctga cggtcactga
    16621 aattgcggaa ttgattcgcg aacggacggg gtatcaatat tctcacggaa ccaaagccca
    16681 actaggaaaa gtgatgtcca aacacggctt cgaatttcat aagggaaaaa acgggagaag
    16741 atacactgta ttcattattg atacggaaca ggtgaaatca aacaggctat atgaataaga
    16801 tttcatctcc ttcgcacgca aaaaggtgag ggttggtgag ggtacttttg caacttttca
    16861 tttttatatt tcttatttct attcttctat tttcttctaa aaaaaaatac gaatgttaga
    16921 aatttaccct cacctaccct caccttttcc tttttcttcc tcaaaaaaac gaggttgtgt
    16981 caaaacgctg acacagcctt ttttttatgc gcaaagccca gactttctca agcccgggct
    17041 ttgttat
//
