LOCUS       gnlProkkaLMOPJJMM_216   4842 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LMOPJJMM_216.
ACCESSION   gnlProkkaLMOPJJMM_216
VERSION     gnlProkkaLMOPJJMM_216
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 04:26:35
            Original ID  :: gnl|Prokka|LMOPJJMM_216
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4842
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..531)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg216_1"
                     /sec_met_domain="APE_KS2 (E-value: 1.7e-17, bitscore: 52.4,
                     seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYPLNIYITAHTLISSLGFGISENKKAIHDYRSGIRMQEAGRIS
                     DSPILAGMIDSVELEKRAKELLEKRAKELDISSYTRLEQLFILTIQEVISQSGVNLQES
                     DCALLLSTTKGNIDLLSNQEKRTNSDKPSGSVQSTIDNPSFLQELSADSPTFLWKMAER
                     IGHFFEAANQVEVI"
     protocluster    1..4842
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[0:4842]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..4842
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..4842
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4842
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             complement(516..959)
                     /locus_tag="ctg216_2"
                     /transl_table=11
                     /translation="MKRKTNQQIAALTNRTTFRVRFSEIDSMQIVWHGEYVRYFEDGRE
                     AFGKQYGLDYMSIYREGYMVPIVDLTCQFKQSLSFGEEAIIETRYIACEAAKIKFEYVI
                     YRATDQSVVATGSTIQVFLNLNKELELINPPFYLEWKKKWNIL"
     CDS             complement(956..1390)
                     /locus_tag="ctg216_3"
                     /transl_table=11
                     /translation="MNREAVIQGEGILNLIPQRPPIVMVDSFFGFEENRSYSGLTVTTD
                     NLFCEAGRLQEPGIIEHIAQSAAARIGFIYTRQGEKVPLGFIGSVDKLKIYNLPEAGMK
                     LFTEITVVQEVFDITLISAQVKTEEELIAECKMKIFIKKE"
     CDS             complement(1387..2457)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 126.4; E-value:
                     2.4e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg216_4"
                     /transl_table=11
                     /translation="MQQNKYDKEPLTAVEAQRLAQEIAFGPIVFQVSRLMLKFGIFQLL
                     ADERKGMTQEEISKACGLPSYGAQVLLEASLTIGTVLLREGRYCLAKAGWFLLNDKMVR
                     VNMDFNHDVNYQGMFHLEEAITNGRPEGLKVFGEWSTIYEGLSSLPSQVQKSWFGFDHY
                     YSDCSFDEALAIVFARHPKTLLDVGGNTGRWATKCVSYDDTVEVTIMDLPQQLEMMRQQ
                     TKELPGATRIHGHGANLLDPEVPFPTRFDAIWMSQFLDCFSEEEVTSILTRAARSMNRE
                     SRLYIMETFWNRQKFDTAAYCLTQISLYFTAMANGNSKMYHSDDMQRCIEAAGLEIEEI
                     HDHLGMGHSIVQCRLK"
     CDS             complement(2444..3379)
                     /locus_tag="ctg216_5"
                     /transl_table=11
                     /translation="MSTWKGKTRGGTFGYLFFIYLIKYLGITAAYLFLSLVVLYFIPFA
                     PKATKSTWFYARHILKYNRIRSLKMLLLNYYRLGQILIDKVAIGNGKVNQYQFKFEQYP
                     EFLQLLNSEQGVIMIGAHVGNWEIGVPFFDDYGKKINIVMYDAEHRRIKEILEKNGQDR
                     EFKIIPVNEDNLTHVFRITEAINQKEYVCFQGDRYLNKEKLLPGILLGQKAPFPAGPFL
                     LASRMKVPVVFYFAMREPGRTYRFHFIIAEPVVRTKEKKAEMALLEQYTVALEQILKRY
                     PEQWFNYYPFWEPAGKQSPDLKEKQKDATE"
     CDS             complement(3382..3633)
                     /NRPS_PKS="Domain: PP-binding (7-75). E-value: 3.8e-14.
                     Score: 44.9. Matches aSDomain:
                     nrpspksdomains_ctg216_6_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg216_6"
                     /sec_met_domain="PP-binding (E-value: 4.7e-15, bitscore:
                     44.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNEEIIEKIRTTLAEEFEVDIDVIQPDAPLMETLELDSLDLVDM
                     VVLVEKNFGFNVTGQDFAGIKTFQDFYDLVITRMQEAK"
     aSDomain        complement(3409..3612)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg216_6_PP-binding.1"
                     /evalue="3.80E-14"
                     /label="ctg216_6_PP-binding.1"
                     /locus_tag="ctg216_6"
                     /protein_end="75"
                     /protein_start="7"
                     /score="44.9"
                     /tool="antismash"
                     /translation="EKIRTTLAEEFEVDIDVIQPDAPLMETLELDSLDLVDMVVLVEKN
                     FGFNVTGQDFAGIKTFQDFYDLV"
     CDS             complement(3655..4842)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (53-393). E-value:
                     2e-53. Score: 173.6. Matches aSDomain:
                     nrpspksdomains_ctg216_7_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 276.2; E-value:
                     8.2e-84)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg216_7"
                     /sec_met_domain="APE_KS1 (E-value: 9.5e-155, bitscore:
                     504.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCIGKNLDEVKDSLYNGKSGIGIDPVRKELGYFSALTGILERPDL
                     KKLLDRRKRLCLPEQGEYAYLATLEAFRNAGIDDAFLEANEVGILYGNDSSAAPVINAV
                     DIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACASGSHAIGMGYLL
                     IKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAEPEKASKPFDKRRDGLIPSGGAA
                     SLVLESYESAVKRGAPILAEVIGYGFSSNGDHISVPNVDGPKRSLQMAIKDAGIALEQI
                     SYINAHATSTPVGDLNEAKAIAEVFEGHHPYVTSTKSMTGHEMWMAGASEVIYSILMMN
                     NGFIAPNLNFEEADEASAQLNIPTQRVNLEFDTFLSNSFGFGGTNSTLIIRQIKE"
     aSDomain        complement(3664..4683)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg216_7_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.00E-53"
                     /label="ctg216_7_PKS_KS.1"
                     /locus_tag="ctg216_7"
                     /protein_end="393"
                     /protein_start="53"
                     /score="173.6"
                     /tool="antismash"
                     /translation="RLCLPEQGEYAYLATLEAFRNAGIDDAFLEANEVGILYGNDSSAA
                     PVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACASGSHAI
                     GMGYLLIKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAEPEKASKPFDKRRDGLI
                     PSGGAASLVLESYESAVKRGAPILAEVIGYGFSSNGDHISVPNVDGPKRSLQMAIKDAG
                     IALEQISYINAHATSTPVGDLNEAKAIAEVFEGHHPYVTSTKSMTGHEMWMAGASEVIY
                     SILMMNNGFIAPNLNFEEADEASAQLNIPTQRVNLEFDTFLSNSFGFGGTNSTLIIRQI
                     "
ORIGIN
        1 gataacttct acctgattgg ctgcctcaaa aaaatgcccg attcgttctg ccattttcca
       61 aagaaaagtc ggactatcgg ctgataattc ctgtaaaaag gaaggattat caattgttga
      121 ttgtacagaa ccgcttggct tgtccgaatt agttcttttt tcttgattgc tcaataaatc
      181 aatatttccc ttcgtagtag agagcaacaa agcacagtcc gactcttgca gattcactcc
      241 cgattgggaa atcacttcct gaatagtcaa tataaacagt tgctctaacc gggtataaga
      301 ggaaatatcc agctcctttg cccgcttttc taatagttct ttagctctct tttccaactc
      361 gacagaatca atcatccctg ccagaatcgg actgtcagaa atccgtccgg cttcctgcat
      421 acgaatcccg cttcgatagt catggattgc ttttttgttt tccgaaatac cgaaacctaa
      481 cgaactaatc agcgtatggg ctgtgatgta tatatttaaa ggatattcca tttctttttc
      541 cattccagat aaaacggagg attgataagc tccagttctt tattcaggtt caggaacact
      601 tgtatggtgc ttccggtggc cactacactc tggtcggtag cccggtagat aacgtattcg
      661 aattttatct tggctgcctc acaggcaata tagcgtgttt cgataatcgc ttcttcacca
      721 aaggacaatg attgcttgaa ctggcaggtt aaatctacga tgggaaccat gtagccttcc
      781 cggtaaatgc tcatataatc caaaccatac tgtttgccga aagcttcccg cccatcttca
      841 aagtagcgca cgtactcgcc atgccataca atctgcatgg agtcaatttc gctgaaccgt
      901 actctgaaag tagtccggtt agtcaaagct gcaatctgtt gatttgtttt ccgtttcatt
      961 cttttttgat aaatattttc atcttacatt cagcaatcag ctcttcttcc gttttcactt
     1021 gtgccgaaat aagcgtaata tcgaatacct cttgtacgac ggtaatctct gtaaataatt
     1081 tcattccggc ttccggcaaa ttgtagattt taagtttgtc taccgaaccg ataaaaccta
     1141 acggaacttt ttcaccctgc cgggtataaa taaacccgat acgtgcagcc gctgattgtg
     1201 cgatatgctc aataattccc ggctcttgca gtctgcctgc ctcacaaaat aaattgtcgg
     1261 tagtgacagt cagtccggaa tatgaacggt tttcttcaaa tccgaagaaa ctgtccacca
     1321 taacgattgg cggacgctgt ggaatcaggt tgagtattcc ttctccttgt atgacggctt
     1381 ctctgttcat ttcaatctgc attgtacgat gctgtgtccc attcctaaat ggtcatgtat
     1441 ctcttcgatt tccaatcctg ctgcttcgat gcatcgttgc atatcgtccg aatgatacat
     1501 cttgctgttt ccgtttgcca tcgctgtaaa atagagactg atttgtgtca ggcaataagc
     1561 ggctgtgtca aatttctgtc ggttccagaa agtctccata atatacaggc ggctctctcg
     1621 gttcatagaa cgggctgcac gggtcaatat gctggtaact tcttcttccg agaaacaatc
     1681 gaggaactgg ctcatccaaa tagcatcgaa ccttgtcggg aaaggcacct ccggatcaag
     1741 cagattggca ccatgaccgt ggatacgtgt agctccgggc agctctttgg tttgttgacg
     1801 catcatctcc aattgttgcg gaagatccat gatggttact tccactgtgt cgtcgtagct
     1861 tacgcatttg gtcgcccagc ggccggtatt gcctcccaca tccaataaag tcttgggatg
     1921 gcgggcgaag acaattgcca gtgcttcatc gaacgaacaa tccgagtaat aatgatcgaa
     1981 accgaaccag ctcttttgta cttgtgaagg cagacttgac aacccttcat agatagtact
     2041 ccattcaccg aatactttca gtccttcagg acgtccgttg gtgatggctt cttccagatg
     2101 aaacattccc tgatagttga catcatggtt gaagtccata ttgacacgta ccattttgtc
     2161 attgagcaga aaccagccgg ctttcgcaag gcagtatcgc ccttcacgca acaatacggt
     2221 gccgatagtc aatgatgcct ccaacaatac ttgtgcgcca taagagggca gcccacaagc
     2281 tttgctgatt tcttcttgcg tcataccttt gcgctcgtcg gccaataact ggaaaattcc
     2341 gaatttaagc ataaggcgtg atacctgaaa aacaataggc ccaaaagcta tttcttgtgc
     2401 caggcgttgt gcctctaccg ctgtcaacgg ctctttgtca tatttattct gttgcatctt
     2461 tttgtttctc ttttaaatcc ggtgactgct ttccggcagg ttcccagaat ggataataat
     2521 tgaaccattg ttccggatag cgttttagta tctgttccaa agcaacagta tattgttcga
     2581 gcagagccat ctccgctttc ttttcttttg ttcgtactac cggttccgct attataaaat
     2641 gaaaacggta agttcttccc ggttccctca ttgcaaagta gaataccacc ggaactttca
     2701 ttcgcgaagc gagcaggaaa ggaccggcag gaaaaggagc tttctgtccc agtaaaattc
     2761 ctggcagaag tttctctttg ttcagataac ggtcgccttg gaaacataca tattcttttt
     2821 ggttgatcgc ctcggttatg cggaaaacgt gtgtcaggtt gtcttcattg acagggataa
     2881 tcttaaattc cctgtcctga ccgtttttct ccaggatctc tttgattcta cgatgttcgg
     2941 catcgtacat cacgatattg attttctttc cgtaatcatc aaagaaagga acgcctattt
     3001 cccagtttcc cacatgggcg ccaatcataa tcactccctg ttcactgttc agcagttgca
     3061 gaaactccgg atactgctcg aatttgaact gatattgatt tacttttcca ttaccgatgg
     3121 ctaccttgtc aatcaggatt tgtcctaatc ggtaatagtt gagtagtaac attttcaaag
     3181 aacgtatcct attgtatttc agaatgtgac gggcataaaa ccaggtgctt ttggttgctt
     3241 tcggagcaaa cggtatgaag tagagcacta ccaggcttag aaaaagataa gcggcagtaa
     3301 tgcccagata cttaatcagg taaataaaga ataagtatcc gaacgttcct ccccgggttt
     3361 tgcctttcca cgtcgacata tttacttggc ttcctgcata cgggtgataa cgagatcgta
     3421 gaagtcctgg aaggttttga tacctgcaaa gtcttgtccg gttacgttga aaccgaaatt
     3481 cttttctacc agtaccacca tgtcgaccaa gtccagactg tccagttcaa gagtttccat
     3541 taacggcgca tccggctgga tgacgtcgat gtctacttca aactcttctg ccagagttgt
     3601 tcttattttc tcgatgattt cttcgtttgt catatatctg ttttctttag taatttattc
     3661 tttgatttgg cgtataatca gggtggaatt ggttcctccg aatccaaacg agttggaaag
     3721 gaacgtatca aattccagat ttacccgttg ggtaggtata ttcaactgtg cggaagcctc
     3781 gtccgcttcc tcgaaattga ggttgggagc gatgaaaccg ttattcatca tgaggatgga
     3841 gtaaatcact tcactggcac ctgccatcca catttcatgt ccggtcatag acttcgtgga
     3901 agtgacatac gggtgatgtc cttcaaatac ttccgcaatg gctttcgctt cgttcaggtc
     3961 gcctaccgga gtggaagtgg cgtgtgcgtt gatataactg atttgttcga gtgcaatacc
     4021 cgcatctttg atggccatct gaagagaacg tttcggaccg tccacgttcg gtacggagat
     4081 atgatctcca ttggaagaga aaccgtaacc gataacttcg gccaaaatgg gagctcccct
     4141 ttttactgcc gattcatagc tctctaatac cagactggcg gctcctccac tcggaatcag
     4201 tccgtcacgt cgtttatcaa aaggtttgga ggctttctcg ggctctgctt cctgggtgga
     4261 aaatgcgctt agcccgtcga aactgccgac cgcataagga tttacttctt gtgcgccacc
     4321 gcaaagaata caatcctgca atcctgattt aatgagcaga taccccatgc caatagcatg
     4381 agaaccactt gcacaagctc cggcaatggt gaagttaact cctctaagct tgaagataac
     4441 cgacaggttc attgtcacgg tagaattcat cgactggaaa atagaaccgg aacctaccaa
     4501 cgctgtgttt ttcttttcac gaatgatgtc cactgcgttg atgacagggg cagcactact
     4561 atcattgcca tacaagatac ccacttcatt agcttcgaga aaagcatcgt caataccggc
     4621 gttgcggaaa gcctccaaag tagcgagata agcatactct ccctgttccg gcaggcagag
     4681 acgtttacga cgatctaata gtttcttcaa gtcgggacgt tccaatatgc ccgttaatgc
     4741 agaaaaatag cccagttctt tccgtaccgg atctatgcca atccccgatt tcccattgta
     4801 tagtgagtct tttacttcat ccaggttctt gccgatgcaa ga
//
