LOCUS       c00344_gnlPro..        24557 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LMOPJJMM_344.
ACCESSION   c00344_gnlPro..
VERSION     c00344_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 00:03:15
            Original ID  :: gnl|Prokka|LMOPJJMM_344
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 569
            Orig. end    :: 25126
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24557
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[10569:15126]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14557
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24557
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24557
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(477..1271)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg344_3"
                     /sec_met_domain="F420_oxidored (E-value: 2.1e-14, bitscore:
                     45.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPIVFIGAGNLATNLAKALYHKGFRIVQVYSRTMESAR
                     TLAEKVEAEYTTDLQEISKDAKLYIVSLKDAALVDLLPQITEGKQNSLLVHTAGSIPMS
                     IWEGYAERYGVFYPMQTFSKQREVNFQEVPFFVEAKRPEDVELLKAVAATLSEKVYEAS
                     SEQRKSLHLAAVFICNFTNHMYALAADLLEKYNLPFDVMLPLIDETARKVHELAPRDAQ
                     TGPAVRYDENVMNNHLAMLVDSPALQEIYKLMSKSIHEHHQL"
     CDS             complement(1279..1614)
                     /locus_tag="ctg344_4"
                     /transl_table=11
                     /translation="MGAAKASNSKDTYLATAVTFIVIGALYLIDKLIHFSTIGLPWVMN
                     KDNMLLYASICFLIFKRDKSIGFVLLGLWLVMNISLVISLLGSLSGYLLPLTLLIVGII
                     LFWFAKR"
     CDS             complement(1617..2171)
                     /locus_tag="ctg344_5"
                     /transl_table=11
                     /translation="MKPENNMENFSELIKNRRSMRKFTDEELTQDQVVTLMKAALMSPS
                     SKRSNSWQFVVIDDKEVLKELSHCKEQASSFIADAALAIVVMADPLASDVWIEDASIAS
                     IMIQLQAEDLGLGSCWVQVRERFTATGMPSDEFVHGILGIPLQLQILSVIAIGHKGMER
                     KPFNEEHLQWEKIHINKFGGK"
     CDS             complement(2168..2332)
                     /locus_tag="ctg344_6"
                     /transl_table=11
                     /translation="MKLFICAKIQYILHLVEYLALFSSYRFPSDNRNEKDTFISYYARF
                     ALSLHTLIK"
     CDS             2334..2558
                     /locus_tag="ctg344_7"
                     /transl_table=11
                     /translation="MKKRITQDDYIKANRKASREAEIEMYGHPICHKRVHQSKKVYNRR
                     KIKAADKKLPYFFVFKIASLSSRHSDTIQ"
     CDS             complement(2647..3189)
                     /locus_tag="ctg344_8"
                     /transl_table=11
                     /translation="MIEEILAYNKQFVENKGYESYITNKYPDKKIAILSCMDTRLTALL
                     PAALGIKNGDVKMIKNAGGVISHPFGSVIRSLLVAIFELGVEEIMVIAHSDCGACHMHS
                     EVMLEKMKARGINPDYIDMMRFCGVDFHSWLDGFEDTEKSVRGTVDFIVRHPLIPSDVT
                     VYGFIIDSTTGELTRIV"
     CDS             complement(3299..5131)
                     /locus_tag="ctg344_9"
                     /transl_table=11
                     /translation="LSVAEGGTDCWITPAGNPDYAKQVIYYDGLATNTNATNKLFGQAY
                     SMIGNCNAVVNRAELLTDGNEKDITTLVAEARCLRAFYYSILVNTYGNVTLTLEESSQD
                     PILTPQRNSIEELYTQIIDDLKFAANNLEDTPYDNNRARVTKKTALGLLARVYAQGGGE
                     YGLTEEGVSYWQRAKEVAEDMILAYGDCLYDDVEDVWAPANNRNNKEALFIAAGPDATN
                     LENWNAGTQCNNNFTYMYPKPNTLTIYPTPDNQNYWYGRTNNNTLAPSKYLLDCFDADY
                     DKRWEVTFTTAFVQFSAVQSGGSYLFTNKKQTLDDGTKPKIGTKHGVNDNISSFTILTQ
                     NIIDTYGLDAKFHNEYIYPYGDLNYTYYDGTWAPKMIAKVWPKGENSGDPSKLQEVKNP
                     YVIPYPVAEDDDRICFYLSKERLSDAEKAKRRYYVINIDDLFDNGQYRKTDIKVTNDKN
                     MYPGFNKYNWLSEDSYSSNLQRKTGDVFIMRMAEVYLIAAEANQQLGNGGKAAEYLNVL
                     KKRAARNDASYNAMKLSNATQNDVMDEYARELCGEYQRWVLMKRHKDSFKQRLAVGNPR
                     AAENFDENKHYLRPISFNFLSQIDNAEEYGNNGY"
     CDS             complement(5348..8458)
                     /locus_tag="ctg344_10"
                     /transl_table=11
                     /translation="MVQVVTQTKTVKGTIIDESGEPLIGVSIVVKGTSTGTITDFNGNF
                     SIDLPAGRKELVISYIGYKEQTVTVTGNGPVNVKMVSDTQALDEVVVVGYGTMKKRDLT
                     GAITSVKSEDVVMNPSSNPMQALQGKVAGLDITRESGQAGSGVKMQLRGNRSFQKDSGN
                     PLFIIDGMPGDYSTLNPNDIESIEVLKDASSTAIYGSSGANGVILITTKGGKEGKAIVN
                     FNAYVGVNGWSRTPEMRSGESYIQTLRDASVGAGDGRWSSVADDKNLFTTDAEWSAHQN
                     GQYIDWVDALLKTSVTQNYSVSVAGGTEKTKAYFSLNFSNEDGQFAQDSYKLYSSKIRV
                     DHKIKKWMKVGIDAQLSYVHQNKADSDLQTLMASNPLGSLYNEDGSINPQPVADPSSTV
                     YNYLLNEDKSLYRNQAQNLKVYFNPYLEITPLKGLTFITRAGASLGYSRSNTFTGEGSV
                     QWYKANQTADGIKAQVKDNRSYNYKWENILTYNFQIKKVHDITLTAVTSWNHNRSDVTT
                     LYQKGVSDNKFLWHNILDGNSATSGSTSYSMSKGMGYVGRLNYSYMGRYLFAASVRHDG
                     SSRLAEGNKWDTFPAFSLGWRISDEKFMESTTNWLSNLKIRFGYGVTGSTAGIDPYSSA
                     ASLDATAVNMILGGVLTPIYKFSQNIPNYLLTWEKSYNTNIGIDAAFLNNRIDVSMEYY
                     NTKTKDVIWNKALPVINGAFSPDGGPKANYTTNLNMCETSNKGFELALNTRNIITKNFT
                     WSSSVTFNHNKEKITKLSGGDSDVLNNGDTGYALALGEAINSYYHYKLDGVWQKGEETD
                     AAVFGAAPGDLKINIPNLVKESDGRFYKIDEETGSAAVDENGNVIYYTSDNKYTPSDAD
                     YQILGHNSPDWSLGFQNNFTWKDFDLSVFVYARYGQMFAYDMLTSYDPKGIRNFPTYFN
                     YWTENNPSNDFPAANANKGLEQYTGYYALRYVDGSFIKIKNITLGYSLPKSILKSAGIE
                     KCRFYATITNPFVFAKSHLLKDYDPEMNGSLKYPLTKQFVFGVNVTF"
     CDS             8827..9825
                     /locus_tag="ctg344_11"
                     /transl_table=11
                     /translation="MPLKLTTYYHGKDIPELPGKNAFHSKELFQIYEATPGYTPLLIVA
                     TEDGRPVARLLAAIRKAKKWLPSSLVKHCVVYSEGEFLDESLSTNKEKAEEIFGDMLEH
                     LTQEASRSCVLIEFRNLNNSMFGYRVFRANDYFPVNWLRVRNSLHSMKKTEDRFSPSRI
                     RQIKKGLKNGAKVEEAHTVEEIHDFSRMLHKVYSSRIRRYFPANDFFRHMNDMLIKGQQ
                     AKIFVVKYKEKIIGGSVCIYSEDDAYLWFSGGMRKTYALQYPGVLAVWKALEDARQRGF
                     RHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRVNWNWLNKLLVKFYV"
     CDS             10001..10405
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg344_12"
                     /sec_met_domain="Glyoxalase_4 (E-value: 3.5e-24, bitscore:
                     76.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             10434..11987
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg344_13"
                     /sec_met_domain="CT_Btheta (E-value: 5.3e-290, bitscore:
                     953.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERLAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYVFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGFELIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPT
                     KPYDMYEVIGAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             12019..12939
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg344_14"
                     /sec_met_domain="OAD_gamma (E-value: 1.8e-15, bitscore:
                     48.5, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLVLNEILINNQSNFQD
                     DYGLHSAWIEIFNKSFGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGKKLLDQIVVPAGALGPNQSYARVSDGAAEW
                     EVKSGSGDKYVTPSTNNKTLDSNSKMEKFEEHDADGVGMSISAMSVVFCGLILLFIAFK
                     IVGKVAVNLSKRNAMKSKGIDKHEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRETPPRK"
     CDS             12964..13395
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.7; E-value:
                     2e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg344_15"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.1e-21, bitscore:
                     67.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKPV
                     AKPVTVRPMPNAPAAPTQVVKPTAPSTGKSGVKSPLPGVILDIKVNVGDTVKKGQTIII
                     LEAMKMENNINADKDGKITAINVNKGDSVLEGNDLVIIE"
     CDS             13397..14557
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg344_16"
                     /sec_met_domain="OAD_beta (E-value: 1.9e-153, bitscore:
                     501.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATVGHVVMILVGLVFIYLAIAK
                     EFEPMLLIPIGFGILIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKNERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFVIATASGVIFVKIFNIFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDSTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(14742..15746)
                     /locus_tag="ctg344_17"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFEVLDAV
                     MEKLPGFPIVLHGSSSVPEEEVETINKYGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAQ"
     CDS             16044..16217
                     /locus_tag="ctg344_18"
                     /transl_table=11
                     /translation="MMMTYLFYKTDYLYRSFFHKTFFYFTEKHYLCALKMTITLFLTKI
                     VTEYKLKKQILK"
     CDS             complement(16549..17763)
                     /locus_tag="ctg344_19"
                     /transl_table=11
                     /translation="MINREQYMEQIVPFIDKPFVKVITGIRRSGKSVVLRLIRDELLRR
                     GVREERIIYLNFESFQWIDLKEAKALYAYIRGQAGDAGKYYILLDEIQEVDGWEKVVNS
                     LLVDLDTDIYVTGSNSRMLSSELATYLTGRYVAFHVMTLSFREYLTFHDLQANDPTLNR
                     KEEFQKYLRMGGFPAIHTADYGYEAIYKIVYDIYSSVILRDTVQRHNIRNVELLERVVK
                     FVFDNIGNKLNAKNIADYFKSQQRKVDMNTIYNYLNALESAFIIQRIPRYDIKGKEILQ
                     TNEKYFVSDLSLIYSVMGYRDRLIAGMLENLVCLELKRRGYEVYVGKQDDKEVDFVAIR
                     REEKIYVQVTYQLASQATVEREFAPLLAINDHYPKYVVSMDSLWQDNVEGVRHRHIADF
                     LLDDA"
     CDS             17957..18364
                     /locus_tag="ctg344_20"
                     /transl_table=11
                     /translation="MEITDLKQMTKEEVFNFIRQRLSFSKELQEQFRHVNKDDLAKEHR
                     RFEMSGNESKTGQCTIFNTAILNEFADLGIYDYTSYLFLDFHNGTPTVYLKYFSENENL
                     EYTFTGYTTTEIIFAILELTIFSGKPKRNRS"
     CDS             complement(18719..18937)
                     /locus_tag="ctg344_21"
                     /transl_table=11
                     /translation="LYHYLNLRLSNTLHQIMINNRHPRQTFIYNKSLIDMLIYDYLRGV
                     SVVSSLGVKKLLIFKFERQYVIYSIKE"
     CDS             19100..19528
                     /locus_tag="ctg344_22"
                     /transl_table=11
                     /translation="MPKWISVEKAVIKYHIEKEAILLWVEMGQFPMLYIDNVPNVDEEC
                     ILELFRRSKAGITAEYIDTLEQLCIDKTMVCEKYAHIIQLKEEEIQLQKEINTLINEIQ
                     AAMKRQNERIRDLKKAIGENNNVIRSDSWIKRLRKKFQ"
     CDS             complement(19608..19862)
                     /locus_tag="ctg344_23"
                     /transl_table=11
                     /translation="LPSWRISLCKVYTVLQILYLQPICHRYLQRSNYLSTSALHAFGCR
                     WQMFSCFFNFMVGGLRIKIVLTTVSHKTNSPLCPPCPLW"
     CDS             20596..21651
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg344_24"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 8.1e-13,
                     bitscore: 39.2, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKEFGFVLAAAILLAGCGQKKETTTTTARPVKTTIVESRSIIRK
                     DFSGIVEAVEYVKLAFRVNGQIIQLPVIEGQKVKKGQLIAAIDPRDIALQYAATKSAYE
                     TASAQVERNKRLLSRQAISVQEYEISLANFQKAKSEYELSANNMRDTKLTAPFDGSIEK
                     RLVENYQRVNSGEGIVQLVNTHNLRIKFTIPDAYLYLLRAKDPRFLVEFDTFKGHVFQA
                     KLEEYLDISTDGTGIPVSITIDDPSFDRDLYAVKPGFTCSIRFTADVGPLVQDSWTIVP
                     LSAVFGESEGNKMYVWVVEDNKVHKREVTVNAPTGEAQALISEGLKPGEKIVIAGVYQL
                     VEGESITTVDR"
     CDS             complement(22166..22903)
                     /locus_tag="ctg344_25"
                     /transl_table=11
                     /translation="MAMINPANEVRFSPTPKKDMISNVPPIEKISDEPISIPARKPITN
                     MIITITIRIDSIRLMINPLLASLAISFSRYRLCSSSPTGISGNNSSSLAFTFLPVCTTS
                     RCGSVETPMPMARLPFTCMMLDGGSMYPFSMTAISPSFTCPALVVITWLRISSTVVYIP
                     LAVTRSCCSPARISPVLIIWFCDCNRLASCFGSMPIPTSLLVEIKILTTSVCVPNRATF
                     ITPSAVTTCVLIRSAQLRISSYV"
     CDS             complement(22881..23456)
                     /locus_tag="ctg344_26"
                     /transl_table=11
                     /translation="MLFHGFHLFHYVIDAIPVGIEHVRPEIRLIERREEVLRHHSHDNQ
                     RSNKEHYHRTQCQCFPANQRAEDGGEFVIERFVIRVFRAVLCFRFQDEITENSGLRQRE
                     HPAQSQRDGKHHKKRFHDFRHGRRSKVEREERTDSDERSPKQSPLRTGCAVYQRFPPVY
                     SAGDGNLCVVRYHDGVIHQHPHGDDKSR"
ORIGIN
        1 tccacagacc atgagctttc agtacttgct ccactacatc acgtccgcaa ccacgtccgc
       61 cgtctgcata agagatatac tttgctacgg atttcacttc cggcacggca tctttcggac
      121 aacatggaag tccacattca cgcatcactt caatatccgg aacatcatcg cccatataga
      181 gaatttcatc atcggtcagt ccgtatttat cacgaaaatc acgatagtcg tgtatcttga
      241 cggcggatcc catatacaga tccttcactc ccagtccttc aaaacggata cgcactgctt
      301 ctgtacggcc accggtgatg atggctatgt gaagtccttt tttcacagcc aactggatag
      361 cgtacccatc tttgatattc acagtacgca tcggctctcc ggaaggatgc aaaggtacgg
      421 ttgtcgaact caatactccg tctacgtcaa aagctaaagc cttgatacgg gataaatcat
      481 agttgatggt gctcatggat acttttgctc attagtttat atatttcctg caatgccgga
      541 gaatctacca acatggcaag atgattgttc atcacattct catcgtaacg gacagcgggt
      601 ccggtctgtg catcacgcgg tgccagttcg tgtactttac gtgccgtttc atctatcagc
      661 ggaagcatga catcgaaagg caagttgtat ttttcaagca aatcagcagc taatgcatac
      721 atgtgatttg tgaaattgca gataaaaaca gcagccaaat gaaggctttt acgctgctcg
      781 gaagaagctt cgtaaacttt ctccgaaaga gtggcggcaa cagctttcaa gagttctaca
      841 tcttccggtc ttttcgcttc aacaaagaaa ggcacttcct gaaaattgac ttcacgttgt
      901 ttgctgaatg tctgcatcgg ataaaatact ccataccgtt ctgcataccc ttcccaaata
      961 ctcatcggga tacttcccgc ggtatgcacc aacaaagaat tttgttttcc ttctgttatc
     1021 tgcggcaaca aatctactaa agcggcatcc ttcaaagata cgatatacaa tttagcatct
     1081 ttggagattt cctgtaaatc tgttgtatat tcagcttcaa ctttctcggc taaagtacga
     1141 gcagattcca tggtccggct atatacctgc acaatacgga agcctttatg atagagagcc
     1201 ttcgccagat tagtagccag gttacctgcg ccgataaaca caatcggtgt atcttctata
     1261 cttctcttca ttatttcctt accgttttgc aaaccagaat aaaatgatgc cgacaatgag
     1321 caaagtcaat ggcagcagat acccggataa cgaacccagc aatgatatta ccagactgat
     1381 attcatcacc agccaaagac caagtaacac aaaaccaatt gatttatcgc gtttgaaaat
     1441 aagaaaacag atcgaagcat acaataacat attgtcttta ttcatcaccc aaggtagtcc
     1501 aatagtggag aaatgaatca gtttatcaat cagataaagt gctccgataa cgataaaggt
     1561 aacagcagta gccaaataag tatctttgct gttactcgct ttagcagctc ccatatttat
     1621 tttcctccga atttatttat gtgaattttc tcccattgaa gatgttcttc gttgaaaggt
     1681 ttacgttcca tccctttatg tccgatagca ataacggaaa gaatttgaag ttgcagagga
     1741 atacccaaga ttccatgaac aaattcatcg gaaggcattc cggtagcagt gaaacgttcg
     1801 cggacctgca cccagcagct tcccaagccg agatcttcgg cctgcaactg tatcatgata
     1861 gaagcaatag aagcatcttc aatccaaaca tcactggcca acggatcggc cattaccaca
     1921 attgccaaag cagcgtcggc aataaatgaa gaagcctgtt ccttacaatg agacaattct
     1981 ttcaatacct ctttatcatc aatcactaca aactgccaac tattactacg tttggaagaa
     2041 ggagacatca aagctgcttt catcaatgta actacctgat cttgtgtcaa ctcttcatcg
     2101 gtgaacttcc gcatactacg acggttcttt attaattcac tgaaattttc catattattt
     2161 tccggtttca tttgattaat gtatgcaaag ataatgcaaa ccgagcgtaa taggaaataa
     2221 aagtatcttt ttcatttcta ttgtcagaag ggaatctata agatgaaaag agtgccaaat
     2281 actccactaa atgaagaata tattgtatct ttgcacagat aaataatttc attatgaaaa
     2341 agcgaattac acaagacgat tacattaaag cgaatcgtaa agctagccgt gaggcagaaa
     2401 ttgagatgta cggacaccct atttgtcaca aacgagtgca ccagtcaaag aaagtatata
     2461 accgcagaaa gataaaggca gccgataaaa agctgcctta tttttttgtc ttcaaaatag
     2521 cgtcactatc ctccagacat agcgacacta tacaatagga atggcgtcac tatcatgata
     2581 ggatagcgtc actatattta ggggattaaa aagaagttta tctatttacc taatctatct
     2641 aattatctat acaatccgag ttaattcccc ggtcgtagaa tcaataataa acccgtagac
     2701 tgtcacatct gaagggatca aaggatgacg cacgataaaa tccaccgttc ctctcaccga
     2761 cttttccgta tcttcgaagc catccagcca cgaatgaaag tcaactccgc agaaacgcat
     2821 catgtcaata taatccggat tgatcccgcg tgctttcatt ttttcgagca ttacttcact
     2881 gtgcatgtgg caagctccac agtcagaatg agcaatcacc attatttcct ctacccccaa
     2941 ctcaaaaata gctacaagta aactacgtat cacgctaccg aaaggatggg aaataacgcc
     3001 acctgcattt tttatcattt ttacatcgcc attcttaatt cctaatgcgg ctggaagcaa
     3061 agctgtcagt cgggtgtcca tacaggaaag aatagctatt ttcttatcgg gatatttatt
     3121 ggtaatatac gattcgtatc ccttgttctc aacaaattgc ttgttgtaag ctaaaatttc
     3181 ttctatcata gttccgctta aattataaag ctctgtttga tgatacaaag atatagaaaa
     3241 aagggacata tcatcacgac atatcccctc tttaatctaa atttaatctg taagagtact
     3301 aatacccatt gtttccatat tcttctgcat tatcaatctg actcaagaag ttaaaagaaa
     3361 tcggacgcaa ataatgcttg ttttcatcaa aattttcagc tgcacgagga ttaccaacag
     3421 caagacgttg tttaaaagaa tctttgtgac gcttcatcaa tacccaacgt tgatattctc
     3481 cacataattc acgagcatat tcgtccataa catcattctg tgtagcatta ctcaatttca
     3541 tagcattgta agatgcatca ttgcgagcgg cacgcttttt cagtacattt aaatattcag
     3601 cagcttttcc gccatttcct aattgttggt tagcttcagc tgcaatcaga tatacttcag
     3661 ccatacgcat aatgaacaca tcacctgtct tacgttgcaa attgctacta tatgaatctt
     3721 ccgacaacca attgtatttg ttgaaaccag ggtacatatt tttgtcatta gtaactttta
     3781 tatctgtttt acgatattgt ccgttatcaa acaaatcatc aatattgatt acataatatc
     3841 tacgtttcgc tttctccgca tccgaaagtc tttcctttga taagtagaaa cagattctat
     3901 catcatcttc agctacaggg taaggtatca cataggggtt cttcacttcc tgcaatttgg
     3961 aaggatcacc gctattttca cctttcggcc aaaccttggc tatcattttg ggcgcccaag
     4021 ttccatcata atatgtataa ttcaaatcac cataaggata aatatactca ttatggaatt
     4081 ttgcatccaa tccataagta tcgattatat tttgagtaag aattgtaaat gaactaatat
     4141 tatcatttac gccatgtttt gttccaattt ttggttttgt accatcatcc aatgtctgct
     4201 tcttattagt aaataaataa ctacctcctg actgtacggc agaaaactgt acaaaagccg
     4261 tagtaaaggt tacttcccac cgcttatcat aatcagcatc aaaacaatcc agcaaatatt
     4321 tggaaggtgc caacgtatta ttattagtac gtccatacca ataattttga ttatccggag
     4381 taggataaat agtgagagta tttggctttg gatacatata agtaaagttg ttattacatt
     4441 gtgttccagc attccagttc tccaaattcg tagcatccgg accggcagca ataaataaag
     4501 cttctttatt atttcgatta tttgccggag cccaaacatc ttccacatca tcatacagac
     4561 agtcaccata cgctaaaatc atgtcctctg ccacttcttt agcacgttgc caataagata
     4621 ctccctcttc tgtcagccca tattcgccac caccttgagc ataaacgcga gccaaaagtc
     4681 ctaacgcggt tttcttagtc acacgcgcac gattattatc ataaggagta tcttcaagat
     4741 tattggccgc aaatttcaaa tcatcaatta tctgcgtata tagttcttca atagagttac
     4801 gctgcggagt caaaatagga tcttgagacg attcttccaa tgttaacgtt acattcccat
     4861 acgtattcac caatatggaa taataaaacg cacgaagaca gcgggcttca gccactaacg
     4921 tcgttatatc tttttcattg ccatccgtta gtaattcagc cctgtttact actgcattac
     4981 aattaccgat catagaataa gcctgaccga ataatttatt tgtagcattc gtattcgtag
     5041 ctaaaccatc ataataaatc acctgcttgg cataatccgg attaccggca ggagttatcc
     5101 agcagtccgt accaccttca gccacagaca agaaatcata gacactgaat aactgcccgt
     5161 aaagtgatga ataacaataa gactgtaatc ctttaagccc atcgaacgtt gcaagaattt
     5221 catctcctgt tttttggctt ggattatact catcaagcga gcaggcagac attgaagcca
     5281 cagcgaatgt aagcgctgct attttataga ttgtactttt catttcaata ctttttttag
     5341 tgaaaaacta gaatgtaaca tttacaccaa atacaaattg tttggtcaat gggtacttca
     5401 gagaaccatt catttcggga tcatagtctt tcagcaaatg gcttttcgca aatacaaacg
     5461 gatttgtaat ggtagcatag aaacgacact tctctatacc ggctgatttt aagatagatt
     5521 tcggcagact atatcccaat gtaatgttct taatctttat aaacgaaccg tctacatagc
     5581 gtaatgcgta atatcccgta tattgttcga gacctttatt agcattggcg gcaggaaaat
     5641 catttgaagg gttgttttca gtccaataat taaaataggt cgggaagtta cgtataccct
     5701 tcgggtcata agacgtcaac atatcataag caaacatctg tccgtaacgt gcataaacaa
     5761 acacacttaa atcaaaatcc ttccaggtaa aattattctg gaatcctaaa gaccaatccg
     5821 gagagttgtg acccagaatt tgataatctg catcacttgg agtatattta ttatcagaag
     5881 tgtaataaat aacattacca ttttcatcta cagcagcact acccgtttct tcatctattt
     5941 tatagaatct accatcagat tcttttacta aattaggtat attgattttc aaatcaccag
     6001 gtgcagcacc aaataccgcc gcatcagttt cctcaccttt ttgccataca ccatccaact
     6061 tataatgata ataagagtta atagcttctc ccaatgccaa tgcataaccg gtgtcaccat
     6121 tattaagcac atctgaatct ccaccggaca atttggttat tttctcttta ttatgattga
     6181 aagttacact tgaactccag gtaaagttct ttgttataat attacgtgta ttaagagcca
     6241 actcaaaacc tttattgcta gtctcacaca tatttaaatt agtagtataa ttcgctttag
     6301 gtccgccatc cggggagaat gctccattaa taacaggaag tgccttgttc catataacat
     6361 cttttgtttt tgtattataa tattccatac tgacatcaat gcgattattt aagaatgcag
     6421 cgtcaatacc aatattcgtg ttatacgact tttcccatgt aagcaaatag ttcggaatat
     6481 tctgtgagaa tttataaatc ggcgtcagaa cacctcctaa tatcatattt acagcagtag
     6541 catccaatga tgcagcagac gaatacggat caatacccgc tgtactaccc gtaacaccat
     6601 atccgaagcg aattttcaga ttactcaacc agttagtcgt actctccata aatttttcat
     6661 cagagattct ccatcccaaa gaaaaagccg ggaaagtatc ccatttatta ccttctgcca
     6721 gtctggaaga gccgtcatgg cggacagatg cagcaaataa atacctaccc atatatgaat
     6781 agttcaaacg gccgacatat cccatcccct tagacatact ataagaagta cttcccgaag
     6841 ttgcggaatt accatcaaga atattatgcc ataagaattt attatcagaa acaccttttt
     6901 gatacaaagt agtgacatcg ctacgattgt gattccaaga tgtaactgca gtaagagtta
     6961 tatcatgcac tttcttaatc tggaaattgt aagtaagtat attttcccac ttataattat
     7021 acgaacggtt gtccttaact tgcgccttaa tgccgtctgc cgtttgattt gccttatacc
     7081 attgaacaga cccctctcct gtgaaagtgt tactacgtga atatcccaaa ctagcaccag
     7141 cacgagtaat aaaagtcagc cctttaagag gagtgatttc caagtaagga ttaaaataga
     7201 ccttaaggtt ttgagcctga ttgcggtaca aacttttatc ctcatttaaa agataattat
     7261 atactgtaga tgaaggatcg gcaacaggtt gcggattgat gcttccatct tcattataca
     7321 acgatccaag aggatttgac gccatcaaag tctgtaaatc agaatcagct ttattttgat
     7381 gtacataaga cagttgagca tcaatgccca ccttcatcca ctttttaatc ttatgatcta
     7441 cccggatttt agatgaataa agtttatagc tatcttgtgc aaactgccca tcctcattag
     7501 agaagttcag agaaaaatat gcctttgtct tttccgttcc accagccaca gaaacagaat
     7561 aattctgtgt tacactggtt ttcaacaaag catccaccca atctatatat tggccatttt
     7621 gatgtgcact ccattcagca tcagtagtaa acagattttt atcatcagca accgaactcc
     7681 aacgtccatc gccagcacca acagatgcat ctctcaaggt ttgtatataa ctttctccac
     7741 tacgcatctc cggagtcctt gaccagccgt ttacacctac gtatgcatta aaattaacaa
     7801 ttgctttgcc ttccttacca cctttagtag taattaaaat aacaccgttc gcaccacttg
     7861 aaccataaat agctgtcgaa gaagcatctt ttaaaacttc aatgctttca atatcattcg
     7921 gattcaatgt agaataatcc cccggcatac catcaattat aaataaagga tttccggaat
     7981 ccttctggaa tgaccggtta ccacgcaact gcatctttac tcccgaaccg gcctgtcccg
     8041 attcacgcgt aatatccaat cctgccacct taccttgtaa agcctgcatc ggatttgaac
     8101 ttggattcat cactacatct tcacttttta cagaagtgat agctcctgtc aaatcgcgtt
     8161 ttttcatcgt accgtaaccc acaacaacca cttcatccaa tgcctgtgtg tccgaaacca
     8221 ttttcacatt gaccggtccg ttgcctgtca ctgtcaccgt ttgttctttg taaccgatat
     8281 aagaaatgac cagttctttt cttcccgccg gaagatcgat agagaagtta ccgttaaaat
     8341 cggtaatcgt acctgtactt gttcctttca caacgataga aactccaatc agcggctccc
     8401 cgctttcatc aatgatagtt cctttcacag ttttcgtttg tgtgacaact tgcaccatag
     8461 tattagaaac tccatcttct gcatacacag aatatgacag aggggcagac aataaagaca
     8521 gccctaaaat catggaagcg cgtctatgat gattcttcca tgcttcaaca aatgcattac
     8581 atctcattcg ttctaattta aagttaatat taattctcgt tgttttgcaa aaactattcg
     8641 attataatct taattaaaga cgaatctaat tttaatacgt actcactttt cataccatat
     8701 ttctcctata aaatatattt tctccattaa atacgcaact atatattata ctttacttca
     8761 agcagctcca acaaattctt tgttttgttg ttgaataaag aataaaaagt gtaaatttgt
     8821 acctagatgc cacttaaact aaccacatat tatcatggga aggacattcc tgaattgccc
     8881 ggaaaaaacg ccttccattc caaagagtta tttcaaattt atgaagcgac tccggggtat
     8941 actcctttat taatagtagc aacagaagac ggcagacctg tggcacgcct gcttgctgcc
     9001 atccgcaaag cgaaaaagtg gcttccctcc tctttagtga aacattgcgt agtatatagc
     9061 gaaggggaat ttctggatga gtcgctttcg accaacaaag aaaaggcaga agaaatcttt
     9121 ggcgatatgc tcgaacatct cacacaagaa gcatcgcgta gctgtgtcct gatcgaattc
     9181 cggaacctca ataattcgat gttcggttac cgggttttcc gtgccaatga ttatttccct
     9241 gtcaattggc tgcgggtacg caattcgctg cacagtatga aaaagacgga agaccggttc
     9301 agcccgtcac gcatccgtca gataaaaaaa ggactcaaga atggagccaa agtagaggag
     9361 gcacataccg tggaagaaat acacgatttc tcacggatgc tgcacaaggt ttattcctcc
     9421 cgcatacgca gatatttccc tgccaacgac tttttccgtc acatgaacga tatgctaatc
     9481 aaaggacaac aggcaaaaat attcgtagta aaatacaaag agaaaatcat tggcggttcc
     9541 gtctgtatct actcggaaga tgacgcgtac ctttggtttt ccggaggaat gagaaagaca
     9601 tacgcacttc agtatccggg agtactggcc gtttggaagg cattggaaga cgcccgccaa
     9661 cggggattcc gccacatgga atttatggat gtaggacttc cgttccgcaa acacggttat
     9721 cgtgatttcg ttctccgatt cggaggaaag cagagcagta cccgccgctg gttccgtgtc
     9781 aattggaatt ggctgaacaa actcttagtc aaattttatg tctaaatgta atctcaagat
     9841 tgcaaaacga ctcttcatgc tccttcccta ccattttttc tgtttaataa tccaataatt
     9901 aaatgcagaa atatttcttt attaggtaag aaatgtcttt ctttgtgctg ttttatgcca
     9961 tataagcaca tgattaaaac caaataaaaa aagtatagtt atgaagattt cacacattga
    10021 acatctgggc attgctgtaa aaagcatcga agaagccctt ccttactacg aaaatgtatt
    10081 aggtctgaag tgttacaaca ttgaaacagt ggaagatcag aaagtaagaa ctgctttttt
    10141 aaaagtaggc gaaaccaaaa ttgaactgtt ggagccgact tgcccggaga gtactattgc
    10201 caaattcatt gaaaacaaag gtgcaggtgt tcatcacgtt gcctttgctg tagaagatgg
    10261 cgtagccaat gctttggcag aagcagaaag caaagaaatc cgccttatcg acaaagctcc
    10321 ccgcaaaggt gccgaaggtt tgaatattgc tttccttcac ccgaaatcaa ctttgggcgt
    10381 gttgacagaa ctctgcgaac attaatcata aactctaaaa ccaacaagaa ctcatgagta
    10441 atcaacttga aaaaattaaa gagcttattg aacgccgtgc cgtagcacgt atcggaggcg
    10501 gtgaaaaagc aattgcgaag caacatgaaa aagggaaata cacagcacgc gagcgtctgg
    10561 ctatgctgct tgacgagggt agcttcgaag aaatggacat gttcgttgag cacagatgca
    10621 cgaacttcgg aatggagaaa aaacattatc cgggagacgg tgtggtaacc ggctgcggta
    10681 caatcgaagg acgtctggta tatgtgttcg cacaggactt cactgtttct gccggttcac
    10741 tgtcagaaac gatgtcattg aagatttgta aaattatgga tcaggccatg aagatgggtg
    10801 ctccttgtat cggtatcaac gactcgggtg gtgcacgtat ccaggaaggt atcaacgctt
    10861 tggcaggtta tgcagaaatc ttccaacgca acatccttgc ttcaggtgtt attccgcaga
    10921 tttccggtat cttcggtcct tgtgccggtg gtgctgttta ttctccggct ctgaccgact
    10981 tcacactgat gatggaaggc acttcttata tgttcctcac cggaccgaaa gtggtgaaga
    11041 ccgttacagg tgaagacgtt agccaggaaa acctcggtgg cgcaagcgtt cactccacta
    11101 aatcgggtgt gactcatttc accgcccaaa cagaagaaga aggtttcgaa ctgattcgca
    11161 aactgttgag ctatattcct caaaacaacc ttgaagaagc tccttatgta gattgcacag
    11221 acccaatcga ccgtctggaa gattctttga acgatattat ccccgacagc cctactaaac
    11281 cgtatgacat gtacgaagtg atcggcgcta ttgtggacaa cggtgaattc cttgaaatcc
    11341 agaaagatta tgcaaagaat atcatcatcg gtttcgcccg cttcaacgga caatcggtag
    11401 gtatcgttgc taatcagcct aagtatctgg ctggtgtgct cgacagcaac gcatctcgta
    11461 agggtgcacg ttttgttcgt ttctgcgatg cattcaatat tcctatcgta tcgttggtag
    11521 acgtaccggg attccttccg ggaacaggtc aggaatacaa tggcgttatc cttcatggtg
    11581 ctaaactgtt gtatgcttac ggtgaagcta ctgtgcctaa ggttactatc acattgcgta
    11641 aatcttacgg tggttctcac atcgtaatga gctgtaagca acttcgcggt gacatgaact
    11701 acgcatggcc tactgccgaa atcgcagtaa tgggtggagc aggagcagta gaagtattgt
    11761 acgcacgcga agccaaagat caggaaaatc ccgctcaatt ccttgctgaa aaagaagcag
    11821 aatacacgaa attgttcgcc aatccttaca atgcagctaa atatggctac atcgacgatg
    11881 tgattgaacc gcgcaacaca cgtttccgtg tgatccgtgc tttgcagcag ttgcagacta
    11941 agaaattgag taatccggct aagaagcatg gtaatattcc gttgtaatcc tacttttcac
    12001 attaaaacaa gaacgattat gaacaaaacc aaaatcggaa tattcctttc tttgctgttg
    12061 ctgattggtc tgacttcttg tggagagcaa aagtcgaaca ataagctggt gctaaacgaa
    12121 atcctgataa acaatcagag taattttcag gacgattacg gattgcacag cgcatggatt
    12181 gaaatattca ataaatcatt cggtagcgcc gacctggcag cttgcttgct gaaagtaagc
    12241 agccaaccgg gcgatacagt tacttatttt atcccgaaag gtgatatact taccttagtg
    12301 aaaccacgcc aacatgcact attctgggca gatggcgaac ctaaccgtgg tactttccat
    12361 accagcttca agctgaatcc ggaaacagct aattgggttg gtctgttcga ctccggcaaa
    12421 aagttgctcg accagattgt agtgcccgca ggcgctctcg gtcccaatca atcatacgct
    12481 cgtgtaagcg acggggcagc tgaatgggaa gtaaaaagtg gaagcggtga caaatacgtg
    12541 actccaagca ccaacaacaa gactcttgac agcaattcca agatggaaaa gtttgaagaa
    12601 cacgatgctg atggcgttgg aatgtccatt tctgccatga gcgtagtatt ctgcggattg
    12661 attcttctct ttattgcttt taagattgta ggaaaagtag ctgttaattt gagcaagcgc
    12721 aacgctatga aatctaaagg cattgacaag catgaagcta aggaactgtc acaggctccg
    12781 ggcgaagtat acgctgctat ttctatggca ttacacgaaa tgcaggatga ggtgcacgac
    12841 gtagaagaaa cggtgctgac catcacccgc gtaaaacgca gctactcacc atggagttcg
    12901 aagatttaca ctttgcgtga aactcctccc agaaagtaag tcacctttta aaaagttaaa
    12961 acgatgaaag aatataaata taaaatcaac ggtaactcat ataaagtaac catcggagat
    13021 attgaagata atatcgctca tgtagaagtg aacggtacac actataaagt agaaatggag
    13081 aaacagccga agcctgttgc gaaacccgtg acagtacgcc cgatgcctaa tgctcctgct
    13141 gctcctactc aagtagtgaa accgaccgct ccgtctaccg gaaaatcagg agtaaaatct
    13201 ccgctgccgg gtgtgatcct cgacatcaaa gtgaatgtag gcgatactgt aaagaaagga
    13261 cagaccatta tcatattgga agccatgaag atggaaaaca atatcaatgc ggataaggac
    13321 ggtaagatta ctgccatcaa cgtcaacaag ggagactctg ttcttgaagg taatgacctc
    13381 gtaattattg aataatatgg gagactttat aaacttttta ggaaataacc tggccgactt
    13441 ctggacatac acaggctttg ccaatgctac ggtagggcat gtagtcatga ttctcgttgg
    13501 cttggtattc atctatttgg caatagccaa agagttcgaa ccaatgctgc tgattcctat
    13561 cggttttggt atattgattg gtaatatacc ttttaatatg gatgccgggc tgaaagtcgg
    13621 tatttatgaa gaaggttctg tattgaatat attgtatcag ggagtgacct ccggctggta
    13681 tccgccactc atctttttgg gtatcggtgc catgacggac ttctcggcac ttatctctaa
    13741 tccaaaattg atgctgattg gtgcagctgc acagttcggt atcttcggtg catatatgat
    13801 cgcattggaa atgggtttcg acccaatgca agccggtgct atcggtatca ttggtggagc
    13861 agacggcccg acggccatct tcctttcttc caagctagca cctaacctga tgggagccat
    13921 tgcggtgtcc gcctactcct atatggcgtt ggttccggtg atacagccgc ctatcatgcg
    13981 tctgctcacc accaagaacg aacgtgtcat ccgcatgaaa ccgccgcgtg ccgtttctca
    14041 cacggagaag gtgattttcc cgatcatcgg tttgttgctg acttgtttcc tggttccttc
    14101 cggtctgcct ttgctgggta tgctgttctt cggtaacctg ttgaaagaaa gtggtgtaac
    14161 ccgccgtttg gctaatactg ccagtggtcc gttgattgat acaatcacta tcctgttggg
    14221 tctgacagta ggtgcttcta cacaagcatc cgaattcctg acgcttgact ctatcaagat
    14281 ctttgccctc ggtgcattgt catttgttat tgcaacggca tctggtgtca tcttcgttaa
    14341 gatcttcaat atcttcctga agaagggtaa taagatcaat ccgttgatcg gtaatgcagg
    14401 tgtttctgct gttcccgact ctgcacgtat ctcgcaagtg attggtttgg aatacgattc
    14461 gaccaactat ttgctgatgc acgctatggg tccgaacgtt gccggagtga tcggttcagc
    14521 tgttgctgcc ggtattctgc ttggattctt gatgtaagaa acattatata atagataaga
    14581 acacccgtgt tacattcagt tgtgacacgg gtgttcttta ttacagccat agtgttatct
    14641 tctctccgtt ctgaaacgat taaacgtcat aaaaaaggct gctaccagtg ttcaaaccgg
    14701 agcagcctct ttcttttatt tatggaataa tccggagatt attactgtgc caatttgttg
    14761 tcagaaccga gcacgttgat gattttgtgc ttgtacagtt tttccatgtt gtcacgagcc
    14821 gggccaagat acttacgtgg gtcgaattca gccggttttt cagcgaaagt cttacggata
    14881 gcagcagtca tagccagacg tgagtcagag tcgatgttga ttttgcaaac agcagactta
    14941 gcagctttac gcaattcttc ttccggaatg ccgatagcag ctttcagtgc accaccatat
    15001 ttgttgatag tttccacttc ttcttccgga actgaagatg atccgtgaag aacgataggg
    15061 aatcccggaa gtttttccat tacagcgtcc aatacttcga aagccaatgg aggaggaacc
    15121 atacggccag tcttcgggtc gatgtggcat tgttccggag taaatttgta agcaccgtga
    15181 gaagtaccga ttgagatagc caaagagtcg caaccagtgc gagtagcgaa gtcgattact
    15241 tcttcagggt cagtatatgt gtgatggtcg gaagaaactt catcttctac accagccaat
    15301 acgccaagtt caccttctac agttacgtca aactggtgag cgtattcaac aactttctta
    15361 gtcaatgcta cgttttcttc gtaaggaaga tgagaaccgt caatcatcac tgaagagaaa
    15421 cctgaatcga tacaagattt gcaagtttcg aatgtatctc cgtggtcaag atgaagaacg
    15481 atttccggat gtgcgcagcc taattcttta gcatattcta cagcaccctg tgccatgtaa
    15541 cgcaacaaag tagcgttagc atactgacga gcacctttag aaacctgaag aatcacagga
    15601 gatttagttt caacagcagc cttgatgata gcctgcattt gttccatatt gttgaagttg
    15661 aatgctggga tagcatatcc acctttgata gccttagcaa acatttctct tgtgtttacc
    15721 aatcctaaat ctttgtaatt taccattttg tttaaagttt attgttagtg aataaaaatt
    15781 ctacgcaaaa gtaagcatta tccatcgaat aacgaacatc ggaaagaaaa atatagtaga
    15841 aaaaggttta aatcagacac catttttctg caggaatatg agtgtgacat tagattgtaa
    15901 tgtctacctt gcaaataaac ggataaaaga cagtaacgcg tattgcttgt atccacgcag
    15961 tcatttatat atgaattaag agaaaaatcc tgttatatgc aggatatata ggtagtctgt
    16021 gccttatata gttgtataaa ccaatgatga tgacatactt attttataaa acagattacc
    16081 tttatcgaag ttttttccat aaaacctttt tctatttcac agaaaagcat tatctttgcg
    16141 ctctgaaaat gaccattaca ctatttctta ccaaaatagt aacagaatat aaattaaaaa
    16201 aacagatact gaaatgaaaa aaggccttca tccagaatca taccgtccgg tagtatttaa
    16261 agatatgtca aatggtgaca tgtttttgtc tagatcaact gtagcaacta aagaaaccat
    16321 cgaattcgaa ggtgaaactt atccgttgct gaagattgaa atctcaaaca cttctcaccc
    16381 gttctataca ggtaaatcta cattggtaga tactgcaggt cgtgttgaca agttcatgag
    16441 ccgttacggt gaccgtaaga agaaataatt cgatctttcg tgaaagatga aaaaagagga
    16501 gattctcgca gagaatttcc tctttttcgt tttctatatt ccttaacgtc aagcatcatc
    16561 caacaagaaa tcggctatat gacgatgcct gacaccctcc acattatcct gccacaagct
    16621 gtccatgcta actacatatt taggataatg gtcgttaatg gcgagcaaag gagcaaactc
    16681 cctctcaaca gtggcctgtg aagctaactg atacgttact tgcacataaa tcttttcttc
    16741 ccgacggatg gctacaaaat ccacttcttt atcatcctgt ttgcctacat acacttcata
    16801 accccttctt ttcaactcca gacagaccag attctccaac atacctgcaa tcaaccggtc
    16861 acgatagccc atcacggaat aaatcaaaga aaggtcactt acaaaatact tttcattcgt
    16921 ctgcagaatt tcctttcctt taatatcata ccggggaata cgttgaatga taaaagcact
    16981 ttccaatgca ttcagataat tatagatggt attcatatcc accttccgtt gctgactttt
    17041 gaagtaatca gctatatttt tagcgttcag cttattgcct atattatcga aaacaaactt
    17101 cactacccgt tcgagcagtt ccacattccg gatattgtga cgctgcaccg tgtcacgaag
    17161 aatgacagaa gaatagatgt cgtagacaat tttatagata gcctcatatc cataatcggc
    17221 agtatgtatg gccggaaatc ctcccatacg gagatatttc tgaaattcct ccttccggtt
    17281 gagtgtcgga tcattggcct gcaagtcatg gaaagtcaga tattctctaa aagacaaggt
    17341 catgacatga aaagcgacat accgtcccgt taaataagtt gccagttcgg acgataacat
    17401 acgtgagttg gagccggtca cataaatatc cgtatccaaa tctaccagaa gtgagttgac
    17461 cactttttcc caaccgtcca cttcctgaat ttcatccaag agaatataat atttacccgc
    17521 atctcctgcc tgcccccgaa tataagcata caaagccttc gcctctttca gatctatcca
    17581 ctgaaaactt tcaaaattca gatagatgat acgttcttca cgaactcctc tcctcaacag
    17641 ttcgtcacga atcagacgca gcactaccga ctttccactg cgacgaatac ccgttatcac
    17701 ttttacaaac ggcttatcta taaaaggaac gatttgttcc atatactgtt cacgattaat
    17761 catattcaaa agtttttagg gttataagca caaagatata ctattttcgg aaagttttta
    17821 gggttataac cctaaataat tccataaatt cagattcttt tagggttata agccgaaaaa
    17881 taaataaaag aaatatgact aaatccgatt tattaccaaa taaagaaagt acctttaccc
    17941 gactaattaa taaaaaatgg aaataaccga tttaaaacaa atgacaaagg aagaagtttt
    18001 taatttcatc agacaacgcc tttctttcag taaagaactg caagaacaat tcagacatgt
    18061 gaataaagac gatctcgcaa aagaacatcg cagattcgaa atgtccggaa atgaatcaaa
    18121 gacaggccaa tgcacgattt tcaacacagc gattctgaac gagtttgccg atcttggcat
    18181 ctatgattat acttcttacc tttttctcga cttccacaat ggcactccaa ccgtttatct
    18241 caaatatttc tccgaaaatg aaaatttgga atatacattt accggatata ccacaacgga
    18301 aatcatcttt gcaattcttg aactgactat cttctccgga aagcccaaaa gaaatcgcag
    18361 ctaaaaaaaa gaattgcacg gaaagacaat gcgaggtcaa aagactttta tggctttcat
    18421 ttaggcacgg attacacgga tttcacggtt ccattagact aaaagccgcg aaatccgtgt
    18481 aatccgtacc taaataatat caatctaata gatggtttca cttttggctc cctccttttt
    18541 atcatcacat tatatttgcc acccgtatag catatttacc atctttatac catactctct
    18601 attctcatac catatttcct gcatttattt cctcttttcc atcctattcc gaaaaaaaca
    18661 tatatctttg tcacacgctt tctgcccatc agcgtgatga aacaggcaaa agcggttttt
    18721 attccttaat ggagtaaata acgtattgtc tctcaaactt aaaaattagc agttttttca
    18781 caccgagaga tgatacaaca gatactccac gtagatagtc gtatatcaac atatcgatta
    18841 gagatttgtt atatataaac gtttggcgtg ggtgtctgtt gtttatcatt atctggtgaa
    18901 gggtattgct aagccttaag tttagataat ggtacaacag cactcacgct tttattgtat
    18961 ccggtcggtt tcaacaatcc ttatacccca accaattccc cacccgaccg aaatcataaa
    19021 aatcgtgggt gttcgttgca cctctccgga caatacgtta tttactcctt tttttataac
    19081 acattaaaac aaaagcaata tgccaaaatg gattagtgta gaaaaagcag tgattaagta
    19141 tcacatcgaa aaagaagcga tcctgctttg ggtggaaatg ggacaattcc ctatgttata
    19201 catagacaat gttccgaacg ttgacgaaga atgtattctg gaactctttc gccgaagtaa
    19261 agccggcatt acagcagaat atattgatac gctggaacaa ctgtgcatag ataaaacaat
    19321 ggtctgcgag aaatacgccc acattattca attgaaagaa gaggaaattc agctgcagaa
    19381 ggaaataaat acgttgataa acgaaataca ggcagcaatg aagagacaaa atgaacggat
    19441 ccgggatttg aaaaaagcga ttggagagaa taataatgtt atacgtagcg acagttggat
    19501 aaaaagacta cgcaaaaaat tccaatagtg aataattatc agcgtaccaa ttaccatgtg
    19561 ggacacaacg taaacaatta gcatattgac acattattgc acggttttta ccacagagga
    19621 cacggagggc acagaggtga atttgtttta tgacttacgg ttgtaagcac aattttgatg
    19681 cgtaatcctc ctaccataaa gttgaaaaaa catgaaaaca tctgccacct gcaaccaaac
    19741 gcgtgtaatg cactagttga taaatagttg gagcgttgca gatacctgtg gcagataggt
    19801 tgcagataaa gtatctgcaa cacagtataa accttacata agctaattct ccaggagggc
    19861 aaaagtttat tgtatacatt aacttcccgt ttccaggcgg ggaactgtcg tttcctgcat
    19921 tagaaattac aatttccacg gtaggaaacg agagtttcta aggcgggaca ctacagtttc
    19981 cacgtaagga tactgtcgtt tccccgtaga gacaccacaa attctccata gagtcacccc
    20041 aattatccca tagctttgca caaaggaatc aagacttttt ctttgattat ataacgtgtt
    20101 gcagatactt tatctgcaac ctatctgcca caggtatctg caacgttcca actatttatt
    20161 aattagtgtg ttacacgcgt ttcgttgcag gtggcagatg tttttatgtt tttcaacttt
    20221 atagtaggaa aaactttcat tcatttctgc actgaaatga gcaaaatagt gcgattttag
    20281 tttatttctg cacacttctt tgctaaatgg gaatttatat ttcaccacaa aggacacgga
    20341 ggtttactat ttttattccc tatagagtaa tacagagtaa tcgtatttat cgctctgttt
    20401 tgcttacgga aagagagaga agaactctgt gtcctctgtg gtgaactcgt aaagttcccg
    20461 tttttttgtg ttccatataa aggttaagag gcaggatatg aaaagacagg aatattgaac
    20521 ataaataaac aggagttgtt ttagtatatt attcgctatt tatcaacgca aaacctctaa
    20581 acatcaacgt ggtatatgaa aaaggaattt ggattcgtcc tggcggctgc aatcttgctg
    20641 gctggctgcg gacagaaaaa agaaacgaca acgacaactg cacgtcccgt aaagactacg
    20701 attgtcgagt caagatcgat tatcagaaaa gatttctcgg gaatcgtgga agcggtggaa
    20761 tatgtgaagc tggctttccg ggtcaacgga caaatcattc agcttcctgt catcgaagga
    20821 cagaaagtga aaaaaggaca gctcatcgcg gctatcgacc ccagagacat tgcgttgcaa
    20881 tatgccgcca cgaaatcggc atacgaaacg gcttcggcac aagtggaacg taacaaacgg
    20941 ctcctctccc ggcaagcgat ctccgtgcag gaatatgaaa tcagcctcgc caacttccag
    21001 aaggcgaagt ctgaatacga actgtctgcc aacaatatgc gcgacaccaa gctgacagct
    21061 cctttcgacg gttctatcga aaaacgactg gtggaaaact atcagcgtgt caactccggt
    21121 gagggtatcg tgcagcttgt caatacacac aatctgcgta tcaaattcac cattccggat
    21181 gcgtatcttt atttgttgcg cgccaaagac ccgcgtttcc ttgtagagtt cgacacattt
    21241 aaaggacacg tgtttcaagc gaaactggaa gaatatcttg atatttctac ggatggcaca
    21301 ggaattccgg tcagcatcac gattgacgat ccgtcattcg accgcgatct gtatgctgtt
    21361 aaacccggtt tcacgtgcag catccgtttc acggcagatg taggcccgtt ggtgcaggat
    21421 agctggacga ttgtaccgct tagtgccgta ttcggtgaaa gcgaagggaa taaaatgtat
    21481 gtctgggtgg tagaagacaa taaagtccac aaacgggaag tgaccgtcaa cgccccgacc
    21541 ggagaagcac aggcgctcat ctcggaaggt ttgaaacccg gtgaaaaaat cgtcatagca
    21601 ggcgtatacc aactagtaga aggagaatct atcacaactg ttgacaggtg atagttgata
    21661 aatgattaag tatcatttat ccgctgtcat tcatcaatta tcaacgatca tttattatga
    21721 gtttagccaa atattcatta gataatacga aaatcatcta tttctttctt gctgtattgc
    21781 tgattggggg aatcacttcc ttcggcaagc tgggtaagaa agaggatgct cctttcgtca
    21841 taaagtcggc ggttattatg acccgctatc cgggtgccga accggcagaa gtggagcggt
    21901 tgattaccga gcctatctct cgtgagattc aaagtatgag cggtgtgtac aagataaaat
    21961 cagaatcgat gtacgggctc tcaaaaatca cattcgagtt gcaaccttcc ttgtcggcaa
    22021 gctccattcc gcagaagtgg gatgagttgc gacggaaggt gctaaatata cagccacagt
    22081 tgccaagcgg tgcttccgca ccgacggttt ccgatgattt cggcgacgtg ttcggtatct
    22141 attacggtct gacggcggac gacggttaca catacgaaga gatgcgcaac tgggcggaac
    22201 ggatcaagac gcaggtagtg acggcggacg gggtgatgaa agtcgccctg ttcgggacgc
    22261 agacggaggt ggtcaatatt tttatttcca ccaataagct cgtaggtatg ggcatcgacc
    22321 cgaaacagct tgccagtctg ttgcaatcgc agaaccagat tatcaatacc ggagaaatcc
    22381 gtgccggcga gcaacagctc cgggtgaccg ccaacggtat gtataccacc gtagacgata
    22441 tccgcaacca ggtgattacc accaaagccg gacaagtgaa actgggcgat atcgccgtca
    22501 tcgaaaaagg atacatggac cctccatcca acatcatgca cgtgaacggc aaacgtgcca
    22561 tcggcatcgg cgtctccacc gacccgcaac gggacgtggt gcagacgggc aagaacgtga
    22621 aagccaaact ggacgaattg ttgccactga tgcctgtggg actggaactg caaagcctgt
    22681 atctggagaa cgaaattgcc aacgaagcca acaacggatt tatcatcaat ctgatcgaat
    22741 cgattctgat tgtaattgtg attatcatgt tggtgatggg tttgcgcgca ggtatgctga
    22801 tcggctcgtc actgattttc tctattggcg gcacattgct tatcatgtct ttcttcggtg
    22861 tcgggctgaa ccgtacttca ttagcgggat ttatcatcgc catggggatg ctggtggata
    22921 acgccatcgt ggtaacggac aacgcacaga ttgccatcgc ccgcggagta gaccggcgga
    22981 aagcgctgat agacggcgca accggtccgc aatggggatt gcttggggct acgttcatcg
    23041 ctatctgttc gttcctcccg ctctaccttg ctccttctgc cgtggcggaa atcgtgaaac
    23101 cgctttttgt ggtgcttgcc atctcgctgg gattgagctg ggtgctcgcg ctgacgcaga
    23161 ccactgtttt cggtaatttc atcctgaaag cgaaagcaaa ggacggcacg aaagacccgt
    23221 atgacaaacc gttctatcac aaattcgcct ccatcctccg cacgctgatt cgcaggaaaa
    23281 cattgacact gggttcgatg gtagtgctct ttgttgcttc gctggttatc atgggaatga
    23341 tgccgcaaaa cttcttccct tctctcgata agccttattt ccgggcggac gtgttctatc
    23401 ccgacgggta tagcatcaat gacgtagtga aagagatgaa atccgtggaa gagcatctgg
    23461 caaagcagcc ggaagtgaag aaagtgtcga tcactttcgg tagcacgccg ttaaggtatt
    23521 acctggcttc tacttcggtg gggccgaaac cgaattttgc caatgtattg gttgaattga
    23581 cggacagtaa atatacaaaa gagtatgaag aagatttcga cgcgtacatg aaggcgaatt
    23641 atccgaatgc gattacccgt accagtctgt tcaaactgtc gcctgcggtg gatgccgcta
    23701 tcgaaatcgg gtttatcggt ccgaatgtgg acacgcttgt ggcactcacc aaccaggctt
    23761 tggagattat gcaccggaat ccggatttaa tcaatgtgcg caattcgtgg ggaaataaag
    23821 ttcctgtatg gaagcctgta tatagtcccg aacgggcgca accgttaggg gtatcgcgtc
    23881 agggaatggc acaaagtatc cagatcggaa ccacaggtat gacgcttgga gagtaccggc
    23941 agggggatca ggtgcttcct atcttattga aggataacac ggtggattcg ttccgcatca
    24001 acgacctgcg cacgttgccc gtgttcggca cggggaatga gacgaccagt ctggaacagg
    24061 tggtatcgga atttgatttc caatatcgtt tctcgaatgt gaaggattac aaccggcaaa
    24121 tggtgatgat ggcgcaatgc gatccgcgtc gcggagtgaa tgcgattgct gctttcaatg
    24181 aggtttggcc gctggtgcag aaagagatta aagtgccgaa ggggtataca atgaagtatt
    24241 tcggggaaca ggaaagtcag gtggagtcta acgaggcgtt ggccaagaat ttaccgttga
    24301 cgttcttcct gatgttcgtc acgctgttgt tcctgttcag gacgtatcgt aagccgacag
    24361 tgatcttgtt gatgttaccg cttattttta tcggtatcgt tttgggattg gtgttgctag
    24421 gcaagtcgtt cgacttcttc tccatccttg gtttgctcgg actgattggg atgaatatca
    24481 aaaatgcgat tgtactggtg gaacagattg atctggaggc aaagacgggc aaaaagccgt
    24541 tggatgctgt tgtcagt
//
