LOCUS       gnlProkkaBMFJGOLO_372  11151 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMFJGOLO_372.
ACCESSION   gnlProkkaBMFJGOLO_372
VERSION     gnlProkkaBMFJGOLO_372
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 05:05:01
            Original ID  :: gnl|Prokka|BMFJGOLO_372
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11151
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11151
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[7238:10563]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7239..10563
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..11151
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11151
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             complement(2..2428)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:MMPL domain-containing transport protein (Score:
                     46.8; E-value: 2.1e-14)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg372_1"
                     /transl_table=11
                     /translation="MTQFFIGLYDYFERHKILFYLSLISCVLLMGFFALQVRFEENITQ
                     FFPDTKDSQNTIKVFDNLKIKDKIIIMLSSADTCHQVEPDSLIEAAGQLQQTLTEKAGG
                     TLIKGIFAQVDQSLIGGATDFVYEHLPLFLTDTDYQRFDSLLTEKGIQATMQKNYTNLL
                     SPAGIALRSYILRDPLGLGSEALKHLQDFQLEANYEIYDEHIFSKDGSTLLMFITPVFS
                     TGSTGKNDELIKILEEELQHIQGESPAIRAEYFGGPSVGVYNARQIKKDTILTSSLALL
                     IIIVFISLVFKRKRSIPLIITPVLFGGLFALFLIFFIKGSISAIAVGAGSAVMGIALSY
                     SIHMLAHQNHVSTVQQLIKEIAYPLTVGSFTTIGAFMGLIFTSSDLLRDFGLFASLALV
                     GTTLFCLIYLPHFLKGQADVKQGCILRIIEKINAYSYEKNKWLVGGILLITVICLFTSQ
                     KVGFNNDMMSLNYEPQHLKQSEEKLMQLFDSDEKTVLFVSVGKDMNQATETYAMTNQKL
                     LALKDQGLIKDYASASQFLISPQEQQLRLKKWKDYWTDEKQQQIREQLETAAAEYRFRP
                     GSFDPFYQWLNQPFGEYHYTAQEDDLSGKLLNEWQTSADSITMLISQIRISDQNKETVY
                     QHFSKDQDVVIFDRSYFANKWVSAINDDFYLILYISSFLIFFALWFSYGRIELTLMSFL
                     PMLVSWVIILGLMGILGIEFNIINIILSTFIFGIGDDFSIFIMDGLQNKYRTGQKVLNS
                     HKTAIFFSAFTTVVGMGALVFAKHPALQSISLISILGMIAVVLVAYTIQPLIFRFF"
     CDS             complement(2425..3615)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 81.1; E-value: 1.6e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg372_2"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.6e-29,
                     bitscore: 90.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEQTSTAYWHEKLKQLGIIVIIPSYNNGKTLADVITSVRFYAPE
                     ILVVNDGSTDETPEILNQEANLHIITHPVNQGKGVALKHGLSFAKKQGFRYAITIDSDG
                     QHFASDIPVLIEAIEKEPDTLLVGSRNLTSDNMPGKNTFANKFSNFWFTLETGIKLQDT
                     QSGYRLYPIQRMNVDKWYYTAKYEFELEALVFAAWGGNPVKNIPVHVYYPPQEERVSHF
                     RPFRDFTRISILNTVLVLVTFLWIVPRNFFRKLTWKNCKQFFSNHITHSPESNLRITAA
                     IMLGVFMGIVPAWGYQMLITLFLAHLFRLNKVIAIVAANISIPPMIPFLLYGSYVTGCK
                     VLGDPVNLHLNELSFENVKSVIEQYLIGSVIFAVVCSILAGTIAFILLTACRKKKI"
     CDS             complement(3751..4218)
                     /locus_tag="ctg372_3"
                     /transl_table=11
                     /translation="MLLDNFYTILSSESSDSTTWTIQIELNPAHTVYQGHFPEHPVVPG
                     VCLLQLIKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXNTSIFLQISFGYQSYRNASDSNRTDSQRDRRRQTPVTGGRYYKGKYCK"
     CDS             complement(4222..4782)
                     /locus_tag="ctg372_4"
                     /transl_table=11
                     /translation="MRRSLRFVSLTVLLFLGIQVQTSCSPRISGEGSTVPPVIELTQGE
                     ESQKYNIQLDFMKHHMSGMLIVRRMPDNEIRIVASTYFGLSLFDFSLHDDQFNVNSCIE
                     PMKKEKVLKLLEMDFRRLFLNGKDVRVKATKDNATQKRTSGKGFGKSVVYITGDTPGEP
                     AQIKIKHPWIRLTIRLDKLSKEI"
     CDS             complement(4757..5392)
                     /locus_tag="ctg372_5"
                     /transl_table=11
                     /translation="MRTLLLYLSLFFLSIATVHAQSMKKMVQKTEFENRLAKEAQTVES
                     IESDFTQVKYLDVFDEKVTSKGKFYYQKSNKICMEYFRPMDYLIVINGSKLKIVSDGKK
                     SIMNLSSNKMMAQMQDMLTACMIGDLSKMSSNYQLEYFEDARYYLVKIKPTNKAVQAYI
                     AGIEIYLDKKDMSVHKLRLSETATNYTEYEFYNKKFNSLKNETKFAIR"
     CDS             complement(5404..6084)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235:polysaccharide deacetylase (Score: 120; E-value:
                     2.1e-36)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg372_6"
                     /transl_table=11
                     /translation="MMIVCLLLCLFLILSFLVYASYSIQSGIYLRSFCKKRTTEKVVAL
                     TFDDGPDPIQTPKVLKVLKEYQATACFFCIGHKIKGNEALLKSIVTEGHLIGNHSYSHS
                     GLFPLYGLSKMKKDLQTCQCELERVTSQPVTLFRPPFGVTNPTIAKAGRQLGYTSIGWS
                     IRTLDTQQSAPDKILARIRKRLEPGAIILLHDRMPGSDQLVKQILDLLKEQGYTVVRPD
                     KLLA"
     CDS             complement(6081..7226)
                     /locus_tag="ctg372_7"
                     /transl_table=11
                     /translation="MQPVYIQRIASIHPQGNHSQGNNPKVNDSPDVSANRPFLQACEPD
                     YKDIIANATLRRRMSRIVKMGVACGLECMGELSPEKIGGIITATGLGCLVDTEKFLNNL
                     LDNEERMLNPTPFIQSTFNTIGAQIALIHQIHTYNMTYVHRGLSFESALLDAMMKIEEG
                     SENILVGAMDEMTETSYIIQQRLGLLKGIEAGEGAQFFLLSREAGEHPLAEIRGLETFT
                     GQHTTEEISSRIIRFLQRNGLECQDIQWLVTGKNKKQSLQGDYHEQITGYKKSTMNEGK
                     STNQRSIINGNSIINEKDRIIKEIMMNESNSIYEELETNLFPESIHLSFKDECGEYPTA
                     SSYAVWKAVKTSINCTTPTNILIYNHHHSINHSLILIRKSV"
     CDS             complement(7239..8546)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (160-423). E-value:
                     8.4e-39. Score: 125.5. Matches aSDomain:
                     nrpspksdomains_ctg372_8_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 249.9; E-value:
                     7.7e-76)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg372_8"
                     /sec_met_domain="APE_KS2 (E-value: 1.2e-112, bitscore:
                     366.2, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIYVTGLGVVSGIGIGVSENIEALQQGKHGIGKVTLFPTALDVP
                     VSEVKRSNEELKQLLSLPPQRTVSRTALLGMIAAKEAMEDAGLNLRISSNQPKNQLLNQ
                     PVTSQKDQQPLRIGFISAPSVGGMDLSERFYESFKKNPKQGRLREVISHDCGASTELIA
                     SYLGINDFITTISTACSSAANAIMLGARLIKHGQLDAAIVGGTDALCRFTLNGFNSLMI
                     LDKIHCRPFDRSRTGLNLGEGAGYLVLQSESSLQRVPYCELSGYANTNEAYHQTGSSPE
                     GDGAFLSMSEAIASSGISPEDIDYINVHGTGTPGNDASEGMALRRIFGEHVPPFSSVKA
                     FIGHTLGASEGIEAVYSVLSIDKGMIYPNLNFTEAMPETELMSETGVKSETGLIPETSF
                     QEGLPIRHVLSNSFGFGGNDSSLLFSATNFPKRTNL"
     aSDomain        complement(7278..8066)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg372_8_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="8.40E-39"
                     /label="ctg372_8_PKS_KS.1"
                     /locus_tag="ctg372_8"
                     /protein_end="423"
                     /protein_start="160"
                     /score="125.5"
                     /tool="antismash"
                     /translation="LIASYLGINDFITTISTACSSAANAIMLGARLIKHGQLDAAIVGG
                     TDALCRFTLNGFNSLMILDKIHCRPFDRSRTGLNLGEGAGYLVLQSESSLQRVPYCELS
                     GYANTNEAYHQTGSSPEGDGAFLSMSEAIASSGISPEDIDYINVHGTGTPGNDASEGMA
                     LRRIFGEHVPPFSSVKAFIGHTLGASEGIEAVYSVLSIDKGMIYPNLNFTEAMPETELM
                     SETGVKSETGLIPETSFQEGLPIRHVLSNSFGFGGNDSSLL"
     CDS             complement(8550..8831)
                     /NRPS_PKS="Domain: PP-binding (22-68). E-value: 5.7e-11.
                     Score: 34.7. Matches aSDomain:
                     nrpspksdomains_ctg372_9_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg372_9"
                     /sec_met_domain="PP-binding (E-value: 1.1e-11, bitscore:
                     34.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLDQTKRELMDEVKGKLIEELNLEEITPEDIDDEAPLFGDEGL
                     GLDSIDALEIILILEREYGIKIENPSEGKQIFYSVCTLTDYIIANRKA"
     aSDomain        complement(8628..8765)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg372_9_PP-binding.1"
                     /evalue="5.70E-11"
                     /label="ctg372_9_PP-binding.1"
                     /locus_tag="ctg372_9"
                     /protein_end="68"
                     /protein_start="22"
                     /score="34.7"
                     /tool="antismash"
                     /translation="LNLEEITPEDIDDEAPLFGDEGLGLDSIDALEIILILEREYGIKI
                     E"
     CDS             complement(8824..10563)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (122-373). E-value:
                     2.6e-29. Score: 94.2. Matches aSDomain:
                     nrpspksdomains_ctg372_10_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 172.1; E-value:
                     3.2e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg372_10"
                     /sec_met_domain="APE_KS2 (E-value: 2.5e-102, bitscore:
                     332.3, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQEAGRISDSPILAGMIDSVELEKRAKEQLEKRAKELDISSYTRL
                     EQLFILTIQEVISQSGVNLQESDCALLLSTTKGNIDLLSDQEKRTNSDKPSGSVQSTID
                     NPSFLQELSADSPTFLWKMAERIGHFFEAANQVEVISNACISGVSALVVAKRWIESGRY
                     KRVIVAGGDILSHFITSGFLSFRSVSAHRCRPYDIQRDGLSLGEACGAVLLETQGNTNH
                     IILSGGAISNDANHISGPSRTGDGLALAINQAMEEAGALPKDISFINAHGTATVYNDEM
                     ESKAIHLAGLSAVPVNSLKPYFGHTLGASGIIETILCIEQLKEGIYYGTLGYETLGVPM
                     PITVYSTHQPMPMKCCIKTASGFGGCNAALVLSLPDAHLKQKTDSPASCKAAVESANIV
                     TIKPGVLENQGTATVNSPETDFAPFIREAYKHLGENNMKFYKMDNLCKLGYVAAGYLLK
                     DTNYRPKEIGIILANASSSLDTDCKHQAIINKEGDKAASPAVFVYTLPNVVLGEICIRH
                     KIQGENTFFVCQQSNVASLEDYARIVMAKGKLRTCIIGWCELLDGHYQAEFKQLNNIST
                     IYE"
     aSDomain        complement(9445..10197)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg372_10_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.60E-29"
                     /label="ctg372_10_PKS_KS.1"
                     /locus_tag="ctg372_10"
                     /protein_end="373"
                     /protein_start="122"
                     /score="94.2"
                     /tool="antismash"
                     /translation="MAERIGHFFEAANQVEVISNACISGVSALVVAKRWIESGRYKRVI
                     VAGGDILSHFITSGFLSFRSVSAHRCRPYDIQRDGLSLGEACGAVLLETQGNTNHIILS
                     GGAISNDANHISGPSRTGDGLALAINQAMEEAGALPKDISFINAHGTATVYNDEMESKA
                     IHLAGLSAVPVNSLKPYFGHTLGASGIIETILCIEQLKEGIYYGTLGYETLGVPMPITV
                     YSTHQPMPMKCCIKTASGFGGCNAALVLS"
     CDS             complement(10770..11150)
                     /locus_tag="ctg372_11"
                     /transl_table=11
                     /translation="MSEIDSMQIVWHGEYVRYFEDGREAFGKQYGLDYMSIYREGYMVP
                     IVDLTCQFKQSLSFGEEAIIETRYIACEAAKIKFEYVIYRATDQSVVATGSTIQVFLNL
                     NKELELINPPFYLEWKKKWNIL"
ORIGIN
        1 tgaagaaccg gaaaatgagt ggctgaatgg tataggcaac caacactact gctatcatgc
       61 cgagaatgga aatcaatgaa atggattgca aagccggatg cttggcaaaa acaagtgctc
      121 ccatgccgac aactgtggtg aaagcagaga agaagatggc tgttttgtga gaattcagta
      181 ccttttggcc tgtacggtat ttgttttgta gcccgtccat aatgaagata ctgaaatcgt
      241 ctccaattcc aaagataaag gtggacagga taatgttgat gatgttgaac tcaatcccca
      301 aaattcccat caatcccagg atgattaccc agctaactag catcgggagg aaactcatca
      361 aggtaagttc gatacgtccg taggagaacc ataatgcgaa gaatatcagg aaagaagaga
      421 tatatagaat caggtaaaag tcgtcattga tggcagatac ccatttattg gcaaagtagg
      481 aacggtcgaa gatgactaca tcctggtctt tgctgaagtg ctgatatacg gtttccttat
      541 tctggtcgct gatccgtatc tggctgataa gcatggtgat ggaatcggca gaagtttgcc
      601 attcgttcag tagcttgccg gataaatcgt cttcttgagc ggtgtagtga tattcaccga
      661 aaggttggtt cagccattga taaaagggat cgaagcttcc cgggcggaaa cggtattcag
      721 cggcagctgt ttccagttgt tcacggattt gttgttgctt ttcatctgtc cagtagtctt
      781 tccatttttt caggcgtagc tgttgctctt gtggcgagat cagaaattgt gaggcggaag
      841 catagtcttt aatcagtccc tgatctttca gtgccaataa cttctgattg gtcattgcat
      901 aagtttcggt ggcctgattc atgtctttgc ctacgctgac aaaaagcact gtcttttcgt
      961 cgctgtcgaa gagctgcatt aatttctctt ccgattgttt gaggtgttga ggttcatagt
     1021 tgaggctcat catgtcgttg ttgaagccga ccttttgtga ggtaaacaaa cagataactg
     1081 taatgaggag aataccgcct accaaccatt tattcttttc gtaagaatat gcgtttattt
     1141 tctcgatgat gcgtaatata catccctgtt tgacgtctgc ctgtcctttc aggaaatgag
     1201 gcaggtaaat gaggcagaaa agagtagtac ctaccaatgc cagggaagcg aacaacccga
     1261 aatcgcgtaa cagatcggaa ctggtgaata tcaatcccat aaatgcgccg atggtagtga
     1321 aactacctac tgtaagcgga taggctatct ctttaatcag ttgttgcacg gtggaaacat
     1381 ggttctgatg tgccaacatg tggatggaat agcttagcgc aatacccatc actgccgaac
     1441 cggctcccac ggcaatggcc gatatacttc ctttgataaa gaaaatcaga aacagggcga
     1501 acaatcctcc gaagagtacc ggagtaataa tcaatggtat cgatcgcttc cgtttaaaca
     1561 cgagtgagat aaacactatg atgataagca gtgccagtga ggaagtcaaa atcgtatctt
     1621 tcttgatctg acgggcgttg tagactccca cggagggacc gccgaaatat tcagctcgaa
     1681 tggcaggaga ttctccctgt atgtgttgta gttcttcttc gagtattttt atcagttcgt
     1741 cattctttcc ggtgctgcct gtactgaata ccggggtaat gaacataagt aaggtggaac
     1801 cgtctttgga aaagatatgt tcgtcataaa tctcgtagtt ggcttccagt tggaagtctt
     1861 gcaaatgttt cagggcttca cttcccagtc cgagcgggtc ccggagaata taacttctta
     1921 atgcgattcc ggcaggagag aggagattgg tatagttctt ctgcatggta gcttgtatac
     1981 ctttctctgt caatagggaa tcgaatcgtt gataatctgt atctgtcagg aaaagcggga
     2041 gatgctcgta gacaaagtct gtggctcctc cgatgaggct ttggtctact tgtgcgaaaa
     2101 ttcccttaat cagggttcct ccggcttttt cagtcagggt ttgttgcagt tgtccggcag
     2161 cttctatcag ggaatcaggt tctacctggt gacaggtatc tgccgaggat agcataatga
     2221 taatcttatc cttgattttg agattgtcga ataccttgat tgtgttttgg gaatctttgg
     2281 tgtcggggaa aaattgtgtg atgttctctt cgaaccttac ttgcagggca aagaacccca
     2341 tcaacaggac acaactgatg agtgacaaat agaacagaat cttgtgcctc tcaaaataat
     2401 catatagtcc gataaaaaac tgggtcatat cttttttttc ctacacgccg tgagcagaat
     2461 gaacgcgatg gttcctgcca gtatgctgca tacgactgca aagataacac ttcctattaa
     2521 atattgctct atgactgatt ttacattttc aaaagaaagt tcgtttaagt gtaggtttac
     2581 ggggtctccc agtactttac agccggttac ataacttccg tacagtaaaa atggtatcat
     2641 cggagggatg ctgatgttgg ctgctacaat agctatgact ttgtttaatc ggaacaaatg
     2701 tgccaaaaac aacgtaatca gcatttgata tccccatgcc ggaacgatgc ccataaatac
     2761 gccgagcatg atggctgccg taatccgcag gttagattcg ggggagtggg tgatgtgatt
     2821 ggagaaaaac tgcttgcaat tcttccaggt cagtttacga aagaagttcc gtggtacaat
     2881 ccaaaggaaa gtgacgagta ccaataccgt attcagaata ctgatacggg tgaaatcacg
     2941 gaacgggcgg aaatgagaaa cccgttcttc ctgtggcgga taataaacgt gtaccggaat
     3001 attttttacg ggattgcctc cccatgctgc aaaaacaagt gcttccagtt cgaactcata
     3061 tttggcagtg taataccact tgtccacatt cattcgttga atagggtaga ggcggtagcc
     3121 ggattgcgta tcttgtagtt tgataccagt ttcgagggtg aaccaaaagt tggaaaactt
     3181 attggcaaag gtattctttc ccggcatatt gtccgaggtc agattacggg agcctaccag
     3241 taacgtgtcc ggttcctttt ctatggcttc aatcaatacg ggaatgtccg aagcgaaatg
     3301 ctgtccgtcg gaatcaatgg tgatggcata tcggaatcct tgcttctttg cgaaagatag
     3361 tccatgtttc aaagctaccc cttttccttg attgacaggg tgggtgatga tgtgaagatt
     3421 agcttcctga ttcagtattt caggtgtttc atccgttgaa ccgtcattga caacaaggat
     3481 ttccggtgca taaaaacgta cacttgttat gacgtctgcc agtgtcttgc cattgttgta
     3541 actcgggatg atgacgatga tccctaattg tttcaacttt tcgtgccaat aggctgtact
     3601 tgtttgctcc ttcatgcttt tggggtaagt gcagctttta gtttaatgaa acattcatct
     3661 tttaccgtgc tttcctcctt tataatgttt ccttttcctg tgacctcctt tacaatttct
     3721 tcttttgcaa tatcctcttt cacaatgctt ttatttacag tatttccctt tatagtacct
     3781 tccgcctgta actggagttt gccttcttct gtctctttga gaatcagtac gattgctatc
     3841 cgaggcgttt ctataggatt gatagccgaa agaaatttgc aggaagatac ttgtgttann
     3901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc ttgataagtt gcaataaaca
     4081 aactccggga actaccggat gttcaggaaa atgtccctga taaacagtgt gggcaggatt
     4141 caactctatc tgaatagtcc aggtggttga atccgatgac tcggaggaaa ggatagtata
     4201 gaagttatca agtagcatat attaaatttc tttagatagt ttatccagac ggatcgttaa
     4261 ccgtatccac ggatgtttga tttttatttg tgccggttca cccggagtgt cgccggtaat
     4321 gtagaccact gattttccaa agccttttcc actggttctt ttttgggtag cattgtcttt
     4381 ggtggctttc acacggacgt cttttccatt taagaacaaa cgcctgaaat ccatctctaa
     4441 cagtttcaat accttttctt ttttcatggg ttcaatgcag ctgttgacat taaattgatc
     4501 gtcatgcaga gaaaaatcga aaaggcttaa cccgaagtag gtagacgcca cgatccggat
     4561 ttcgttatca ggcatacggc gtactatcag cataccactc atgtgatgtt tcatgaaatc
     4621 cagttggata ttgtattttt gtgattcttc cccttgtgtc agttcgataa caggaggcac
     4681 agtactgcct tccccgctta ttcgtggaga gcaggacgtt tgaacctgta ttcctaagaa
     4741 taacagaacc gtcaggctaa cgaatcgcaa acttcgtctc attcttcaga gagttgaact
     4801 ttttattata gaattcgtat tctgtgtagt ttgtagctgt ttcggacaga cggagtttgt
     4861 gcaccgacat atctttcttg tccaaataaa tttcgatacc ggcaatatag gcttgtactg
     4921 ctttgttagt cggcttaatt ttaaccaaat aatatcgtgc gtcttcaaaa tattccagct
     4981 ggtagttgga tgacatctta gacaggtcgc ctatcataca cgcagttagc atatcctgca
     5041 tctgtgccat cattttgttc gaacttaggt tcataatact tttcttgcca tccgatacaa
     5101 ttttgagttt actgccattt atcacgatga gataatccat cgggcggaag tattccatac
     5161 agattttatt gcttttttgg tagtagaact tccctttgga agtaaccttt tcgtcgaata
     5221 catcgagata tttcacttgg gtaaaatcgc tttcgataga ctctacggtt tgtgcctcct
     5281 ttgccaagcg gttttcaaac tcggtctttt gcaccatctt tttcatgctt tgtgcatgga
     5341 cggtggcgat agacaagaag aaaagcgata agtatagtaa taaagttctc atacattttt
     5401 attttatgcc aatagtttgt ccggacggac aacggtatat ccttgttctt ttagtaaatc
     5461 cagtatttgt ttcactaact ggtcgctgcc gggcatccgg tcgtgcaaca gaatgatggc
     5521 tcccggttca agacgtttcc gaatcctggc aagtattttg tccggagctg actgttgcgt
     5581 atctaatgta cggatgctcc atccgatcga ggtgtatcct aactgtcggc cagctttcgc
     5641 aatcgtagga ttagtgacac cgaatggcgg acgaaacaaa gtaaccggct gcgaagttac
     5701 tcgttctagt tcacactgac aagtttgcag gtcttttttc attttagaga gtccatatag
     5761 tggaaataaa ccggaatgac tatatgaatg atttccaatt agatgacctt ctgttactat
     5821 acttttcaat aaggcttcat ttccttttat cttgtgtccg atacagaaaa aacaggcagt
     5881 tgcttgatat tcttttagta ccttcaatac tttgggcgtt tgaatgggat cgggaccgtc
     5941 gtcaaaagtc agggcgacaa ctttttccgt agtacgtttt ttgcaaaacg accgtagata
     6001 aattcccgac tggatgctat aggaagcata aacgagaaag gacagtatca agaataaaca
     6061 tagaaggagg caaacaatca tcatacgctt ttccgaatta gaatcaatga gtgattgatg
     6121 gagtggtgat gattataaat caatatattg gtaggggtag tgcagtttat tgatgtcttt
     6181 actgctttcc atacggcata cgatgaggcg gtaggatatt ctccacattc gtccttaaaa
     6241 ctaagatgaa tactttccgg gaaaaggttg gtttcaagct cttcatagat agaattgctt
     6301 tcattcatca taatctcctt aattatccta tctttttcat ttatgatact attcccgttt
     6361 ataatacttc tctgattcgt actcttccct tcattcatag tactcttctt ataaccagtg
     6421 atttgctcgt ggtaatcacc ttgaagggat tgttttttgt tctttccggt aactaaccat
     6481 tgaatatcct gacactctaa tccgtttcgt tgtaaaaaac gaataattcg ggaactgatt
     6541 tcttctgtcg tatgttgtcc cgtgaaagtt tcaagtcctc gtatttctgc taacggatgc
     6601 tctccggctt cccggcttaa taggaagaat tgagcgcctt ctccggcttc tattcctttc
     6661 agcaggccca gtcgttgctg aatgatgtaa ctggtttctg tcatttcgtc catggctccc
     6721 accagtatat tctcgcttcc ttcttctatt ttcatcatgg catccagcaa agcgctttca
     6781 aaacttagtc cccggtgaac ataagtcatg ttataggtgt gtatttgatg aattaaagct
     6841 atttgtgcac caattgtatt gaatgtcgac tgaataaaag gagtaggatt cagcatccgc
     6901 tcttcattat ctaacaggtt gttcagaaac ttttccgtat caaccaggca gcccaaccct
     6961 gtggctgtga taattccccc tatcttctcg ggagatagtt cgcccataca ttccaatccg
     7021 caagctactc ccattttgac aatacggctc atgcgcctgc gcaaagttgc attggcaata
     7081 atatccttat aatcgggttc acaagcctga agaaaaggac ggtttgctga aacatcgggc
     7141 gaatcattta ctttcggatt atttccttgt gaatgatttc cttgtggatg gatagaagcg
     7201 atgcgttgaa tataaactgg ctgcataggc tcaaaaactt aaaggttcgt tcgttttgga
     7261 aaattcgttg cggaaaagag gagcgacgag tcgtttcccc caaagccgaa agaattggat
     7321 aatacatggc ggatcggcaa tccttcctgg aaagacgttt ccggtatcaa tcctgtttct
     7381 gattttactc ctgtttctga catcagctct gtttccggca tagcctccgt gaaattcaga
     7441 ttcggataaa tcatgccttt atctatggaa agaacggaat aaacagcttc aattccttcg
     7501 gaagctccta aggtgtgtcc gataaaagct tttaccgaac taaacggtgg aacatgttct
     7561 ccgaagattc ttcgcaatgc cataccttcc gatgcgtcat taccgggagt acctgtccca
     7621 tgtacgttga tataatcaat atcttcagga gaaatgccac tggaagcgat ggcttcactc
     7681 attgatagaa aggcgccatc tccttcggga gaacttcctg tttgatgata agcttcattt
     7741 gtattagcat aaccgcttag ttcacagtaa ggaactcttt ggagtgaact ttctgattga
     7801 agcactaaat aacccgcgcc ttctcccaaa tttaatccgg tacgcgaacg gtcaaaagga
     7861 cgacaatgta ttttgtccaa aatcatgaga gagttgaacc cattgagcgt aaaccggcaa
     7921 agtgcatccg tacctccgac gatagcagca tccagttgtc cgtgttttat cagtctcgct
     7981 cccaacataa tagcattggc tgccgatgaa caggcagtac tgatggtggt tataaaatca
     8041 ttgataccta aatacgaagc tattaattcg gtactggctc cgcagtcgtg tgaaatcact
     8101 tcccgcaatc gtccttgttt cgggtttttc ttgaacgatt catagaaacg ctcgcttaag
     8161 tccataccgc cgacagaagg ggcggaaata aaaccaatac gtaacggttg ctggtctttt
     8221 tgcgaggtta ctggctgatt cagtaactga ttttttggct gattggatga tatacgcaag
     8281 tttagtcctg catcttccat cgcttctttg gcggctatca tgcctagcaa tgctgtgcgt
     8341 gatactgtac gctgcggagg taaagataat agttgtttaa gttcttcatt gctacgtttc
     8401 acttcagata cgggtacatc gagagcagtc gggaaaagag ttacctttcc gatgccatgc
     8461 ttcccttgtt gtagtgcctc tatattttcg gaaactccga tgccgatgcc cgaaacaact
     8521 cccaatccgg tgacgtaaat cttcataagt taagctttcc gattagcaat gatgtagtca
     8581 gtcagtgtac ataccgagta gaagatttgt tttccttcac taggattctc tattttaatg
     8641 ccatattcac gttccaaaat caggatgatt tcgagtgcgt caatggagtc aaggccaaga
     8701 ccttcgtcgc caaacagagg ggcttcatcg tcaatatctt ccggagtgat ttcttcaagg
     8761 ttcaactctt cgattagttt acctttcact tcgtccatca gttctctttt ggtttgatct
     8821 aaattattca taaatcgttg atatattatt aagttgttta aattctgctt ggtaatgtcc
     8881 gtccagtagt tcgcaccagc ctatgatgca tgtgcgtaac ttacctttcg ccatcacaat
     8941 tcttgcgtaa tcctctaagg aagcaacgtt ggattgctgg cagacaaaga atgtattttc
     9001 tccctgaatt ttgtgtcgta tacagatttc tcccaatact acattgggga gagtgtagac
     9061 aaacacggca ggactggcgg ctttatctcc ttctttattg atgatagctt gatgtttgca
     9121 gtccgtatcc aaagaggaag atgcattggc tagaatgatt ccaatctctt tcggtcggta
     9181 gttggtatct ttcaataaat atccggcagc tacatatccc agcttacaaa ggttatccat
     9241 cttgtagaac ttcatattgt tttctcccag atgcttgtat gcttcccgga taaacggcgc
     9301 aaagtcagtc tccggagaat tgactgtagc tgttccttgg ttttctagca ctcccggttt
     9361 gatcgtgact atattggctg attctacggc agctttacag gatgccggag aatcggtttt
     9421 ctgtttcaaa tgagcatctg ggagagataa taccagtgca gcattacagc ctccgaaacc
     9481 agaagcggtt ttgatacaac atttcatcgg catcggctga tgagtgctat aaacggtgat
     9541 aggcatggga acacctagtg tctcatatcc taaagttccg tagtatattc cttcttttag
     9601 ttgctctatg caaagtatgg tttcaataat gcccgaagct cctaatgtat gcccgaaata
     9661 aggcttaagg ctattcaccg gaactgcaga taatcctgcc aaatgtatgg ctttggattc
     9721 catttcgtca ttataaaccg tagctgttcc gtgtgcattg ataaaactga tatctttagg
     9781 aagtgctccg gcttcttcca ttgcctgatt gatagccagc gccagtccgt ctcctgtccg
     9841 ggaaggaccg gatatatggt tggcatcatt gctgatcgct cctccggata gaataatatg
     9901 atttgtgttt ccttgcgttt ctaaaagaac agctccacag gcttcgccta gacttaatcc
     9961 gtcccgctgt atatcgtatg gccggcatcg gtgtgcgctg actgaccgga aagacaggaa
    10021 accgctggta ataaaatgag aaagaatatc cccgccagcg acaatcactc gtttgtaacg
    10081 ccctgattct atccatctct tggcaacaac cagtgccgag actccagata tacaggcgtt
    10141 ggagataact tctacctgat tggctgcctc aaaaaaatgc ccgattcgtt ctgccatttt
    10201 ccaaagaaaa gtcggactat cggctgataa ttcctgtaaa aaggaaggat tatcaattgt
    10261 tgattgtaca gaaccgcttg gcttgtccga attagttctt ttttcttgat cgctcaataa
    10321 atcaatattt cccttcgtag tagagagcaa caaagcacag tccgattctt gcagattcac
    10381 tcccgattgg gaaatcactt cctgaatagt caatataaac agttgctcca accgggtata
    10441 agaggaaata tccagctcct ttgcccgctt ttctaattgt tctttagctc tcttttccaa
    10501 ctcgacagaa tcaatcatcc ctgccagaat cggactgtca gaaatccgtc cggcttcctg
    10561 catacgaatc ccgcttcgat agtcatggat tgcttttttg ttttccgaaa taccgaaacc
    10621 taacgaacta atcagcgtat gggctgnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10741 nnnnnnnnnn nnnnnnnnnn ngtatatatt taaaggatat tccatttctt tttccattcc
    10801 agataaaacg gaggattgat aagctccagt tctttattca ggttcaggaa cacttgtatg
    10861 gtgcttccgg tggccactac actttggtcg gtagcccggt agataacgta ttcgaatttt
    10921 atcttggctg cctcacaggc aatatagcgt gtttcgataa tcgcttcttc accaaaggac
    10981 aatgattgct tgaactggca ggttaaatct acgatgggaa ccatgtagcc ttcccggtaa
    11041 atgctcatat aatccaaacc atactgtttg ccgaaagctt cccgcccatc ttcaaagtag
    11101 cgcacgtact cgccatgcca tacaatctgc atggagtcta tttcgctgaa c
//
